LTBP1 (Human) Recombinant Protein (Q01)
Catalog # : H00004052-Q01 規格 : [ 10 ug ] [ 25 ug ] List All
Specification Application Image
Product Human LTBP1 partial ORF ( NP_000618, 403 a.a. - 500 a.a.) Enzyme-linked Immunoabsorbent Assay Description: recombinant protein with GST-tag at N-terminal. Western Blot (Recombinant Sequence: CPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPA protein) KEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLS Antibody Production Host: Wheat Germ (in vitro) Protein Array Theoretical MW 36.52 (kDa):
Preparation in vitro wheat germ expression system Method:
Purification: Glutathione Sepharose 4 Fast Flow
Quality Control 12.5% SDS-PAGE Stained with Coomassie Blue. Testing:
Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Store at -80°C. Aliquot to avoid repeated freezing and thawing. Instruction:
Note: Best use within three months from the date of receipt of this protein.
MSDS: Download
Datasheet: Download
Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array Page 1 of 2 2019/9/17 Gene Information
Entrez GeneID: 4052
GeneBank NM_000627 Accession#:
Protein NP_000618 Accession#:
Gene Name: LTBP1
Gene Alias: MGC163161
Gene latent transforming growth factor beta binding protein 1 Description:
Omim ID: 150390
Gene Ontology: Hyperlink
Gene Summary: The protein encoded by this gene belongs to the family of latent TGF- beta binding proteins (LTBPs). The secretion and activation of TGF- betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other TGF-beta1-BP-1 Designations:
Gene Pathway TGF-beta signaling pathway
Related Disease Aortic Aneurysm, Abdominal Colonic Neoplasms Colorectal Neoplasms Disease Progression Esophageal Neoplasms Genetic Predisposition to Disease Head and Neck Neoplasms Hepatitis C, Chronic Laryngeal Neoplasms Liver Cirrhosis Mouth Neoplasms Ovarian cancer Ovarian Neoplasms Pharyngeal Neoplasms Rectal Neoplasms Tobacco Use Disorder
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