KPNA5 Antibody Cat. No.: 26-913

KPNA5 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human KPNA5.

TESTED APPLICATIONS: ELISA, WB

KPNA5 antibody can be used for detection of KPNA5 by ELISA at 1:312500. KPNA5 APPLICATIONS: antibody can be used for detection of KPNA5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. 1205 - Jurkat Cell Lysate

PREDICTED MOLECULAR 61 kDa WEIGHT:

Properties

PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

September 30, 2021 1 https://www.prosci-inc.com/kpna5-antibody-26-913.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: KPNA5 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: KPNA5

ALTERNATE NAMES: KPNA5, IPOA6, SRP6

ACCESSION NO.: NP_002260

PROTEIN GI NO.: 39812229

GENE ID: 3841

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the complex (NPC) which consists of 60-100 and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic sequences known as nuclear localization signals (NLSs). KPNA5 belongs to the alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus.The transport of molecules between the nucleus and the cytoplasm in eukaryotic BACKGROUND: cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus. Publication Note: This RefSeq record includes a subset of the publications that are available for this . Please see the Gene record to access additional publications.

REFERENCES: 1) Singh, A.P., (2007) Cell 131 (3), 492-504.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 30, 2021 2 https://www.prosci-inc.com/kpna5-antibody-26-913.html