DUID/DRE Toxicology Scope of Testing

Effective Date:3/23/2020 8150B 8151B 8152B* 1480B 9560B Compound Description DUID/DRE Panel DUID/DRE Panel Expanded Drug Designer Opioids Synthetic ProofPOSITIVE with alcohol Screen Add-on Cannabinoids 10-Hydroxycarbazepine X 11-Hydroxy Delta-9 THC X X 2-Furanylfentanyl X X 4-ANPP X X 4-cyano-CUMYL-BINACA X 4-fluoro-MDMB-BINACA X 5-fluoro-EDMB-PINACA X 5-fluoro-MDMB-PICA X 5-fluoro-MDMB-PINACA / 5-fluoro-EMB-PINACA X 5-fluoro-MMB-PINACA X 5-fluoro-NA-PIC X 5-fluoro-QU-PINAC X 6-Monoacetylmorphine - Free X X 7-Amino Clonazepam X X 7-Amino Flunitrazepam X 9-Hydroxyrisperidone X ADAMANTYL-FUBINACA X ADMB-CHMINACA X ADMB-FUBICA X ADMB-FUBINACA X AMB-CHMINACA X AMB-FUBINACA X Acetone X Acetyl Fentanyl X X Acryl Fentanyl X X Alfentanil X Alpha-Hydroxyalprazolam X X Alprazolam X X Amitriptyline X Amobarbital X X Amoxapine X Amphetamine X X Amphetamines X X Aripiprazole X Barbiturates X X Benzodiazepines X X Benzoylecgonine X X Blood Alcohol Concentration (BAC) X Brompheniramine X Buprenorphine - Free X X Buprenorphine / Metabolite X X Bupropion X Buspirone X Butabarbital X X Butalbital X X

3/23/2020 12:47:46 PM 200 Welsh Rd. Horsham, PA 19044-2208 Page 1 of 5 8150B 8151B 8152B* 1480B 9560B Compound Description DUID/DRE Panel DUID/DRE Panel Expanded Drug Designer Opioids Synthetic ProofPOSITIVE with alcohol Screen Add-on Cannabinoids Butylone X Butyrylfentanyl X X CUMYL-THPINACA X Caffeine X Cannabinoids X X Carbamazepine X Carbamazepine-10,11-Epoxide X Carfentanil X X Carisoprodol X X Carisoprodol / Metabolite X X Chlordiazepoxide X X Chlorpheniramine X Chlorpromazine X Citalopram / Escitalopram X Clobazam X X Clomipramine X Clonazepam X X Clonazolam X Clonidine X Clozapine X Cocaethylene X X Cocaine X X Cocaine / Metabolites X X Codeine - Free X X Cyclobenzaprine X Cyclopropylfentanyl X X Delorazepam X Delta-9 Carboxy THC X X Delta-9 THC X X Desalkylflurazepam X X Desipramine X Desmethylclomipramine X Desmethyldoxepin X Desmethylsertraline X Desmethyltrimipramine X Dextro / Levo Methorphan X Dextrorphan / Levorphanol X Diazepam X X Dibutylone X Diclazepam X Dicyclomine X Dihydrocodeine / Hydrocodol - Free X X Diltiazem X Diphenhydramine X Doxepin X Doxylamine X Duloxetine X EDDP X X Ephedrine X X Estazolam X X Eszopiclone / Zopiclone X Ethanol X Etizolam X Fentanyl X X

3/23/2020 12:47:46 PM 200 Welsh Rd. Horsham, PA 19044-2208 Page 2 of 5 8150B 8151B 8152B* 1480B 9560B Compound Description DUID/DRE Panel DUID/DRE Panel Expanded Drug Designer Opioids Synthetic ProofPOSITIVE with alcohol Screen Add-on Cannabinoids Fentanyl / Acetyl Fentanyl X X Flubromazolam X Flunitrazepam X Fluoxetine X Fluphenazine X Flurazepam X X Fluvoxamine X Gabapentin X Haloperidol X Hydrocodone - Free X X Hydromorphone - Free X X Hydroxybupropion X Hydroxyethylflurazepam X X Hydroxytriazolam X X Hydroxyzine X Iloperidone X Imipramine X Isobutyrylfentanyl X X Isopropanol X Ketamine X LSD X Lamotrigine X Levetiracetam X Lorazepam X X Loxapine X MDA X X MDEA X X MDMA X X MDMB-CHMCZCA X MDMB-CHMICA X MDMB-CHMINAC X MDMB-FUBICA X MDMB-FUBINACA / EMB-FUBINACA X MMB-CHMICA X MMB-CHMINACA X MMB-FUBICA X MMB-FUBINACA X Maprotiline X Meperidine X Meprobamate X X Mescaline X Mesoridazine X Metaxalone X Methadone X X Methadone / Metabolite X X Methamphetamine X X Methamphetamine / MDMA X X Methanol X Methaqualone X Methocarbamol X Methoxyacetylfentanyl X X Methylphenidate X Mexiletine X Midazolam X X

3/23/2020 12:47:46 PM 200 Welsh Rd. Horsham, PA 19044-2208 Page 3 of 5 8150B 8151B 8152B* 1480B 9560B Compound Description DUID/DRE Panel DUID/DRE Panel Expanded Drug Designer Opioids Synthetic ProofPOSITIVE with alcohol Screen Add-on Cannabinoids Mirtazapine X Mitragynine X Morphine - Free X X N-Ethyl Pentylone X NA-FUBIC X NA-FUBIM X Norbuprenorphine - Free X X Norclozapine X Nordiazepam X X Norfentanyl X X Norflunitrazepam X Norfluoxetine X Norketamine X Normeperidine X Norpropoxyphene X Norpseudoephedrine X X Nortriptyline X O-Desmethyltramadol X X O-Desmethylvenlafaxine X Olanzapine X Opiates X X Oxazepam X X Oxycodone - Free X X Oxycodone / Oxymorphone X X Oxymorphone - Free X X Paroxetine X Pentobarbital X X Perphenazine X Phenazepam X Phencyclidine X X Pheniramine X Phenobarbital X X Phentermine X X Phenylethylmalonamide (PEMA) X Phenylpropanolamine X X Phenytoin X Primidone X Promazine X Promethazine X Propoxyphene X Pseudoephedrine X X Psilocin X Quetiapine X Risperidone X Risperidone and 9-Hydroxyrisperidone - Total X Ritalinic Acid X Scope Statement X Secobarbital X X Sertraline X Sufentanil X THF-F X Tapentadol X Tapentadol - Free X Temazepam X X

3/23/2020 12:47:46 PM 200 Welsh Rd. Horsham, PA 19044-2208 Page 4 of 5 8150B 8151B 8152B* 1480B 9560B Compound Description DUID/DRE Panel DUID/DRE Panel Expanded Drug Designer Opioids Synthetic ProofPOSITIVE with alcohol Screen Add-on Cannabinoids Thioridazine X Topiramate X Tramadol X X Tramadol / Metabolite X X Trazodone X Triazolam X X Trifluoperazine X Trihexyphenidyl X Trimipramine X U-47700 X X U-49900 X U-51754 X Valeryl Fentanyl X X Venlafaxine X Verapamil X Xylazine X Zaleplon X Ziprasidone X Zolpidem X X Zonisamide X cis-3-Methylfentanyl X X mCPP X meta-Methylmethoxyacetylfentanyl X ortho-Fluorofentanyl X para-Fluorobutyrylfentanyl X X para-Fluorofentanyl X para-Fluoroisobutyrylfentanyl X X para-Methylmethoxyacetylfentanyl X trans-3-Methylfentanyl X X

* The new Novel Psychoactive Substances (NPS) have created challenges due to their evolving development, increasing emergence, and sometimes cessation. NMS Labs is constantly evaluating information from the media, drug user forums, and forensic casework to identify emerging NPS. NMS Labs develops advanced lab testing to report these findings to our clients. In addition to the compounds listed above, NMS Labs has identified several additional NPS substances that may be detected in casework.

As of 3/20/20, NMS Labs identified Bromazepam, Delorazepam, Deschloroetizolam, Flualprazolam, Meclonazepam, Pyrazolam, 25B-NBOME, 25C-NBOME, 25I-NBOME, 3-Fluorophenmetrazine, 3-MeO-PCP, Ethylone, Eutylone, Pentylone, N-Ethyl Hexedrone, Isotonitazene, Tianeptine, 4-Chloro-Alpha-PVP, alpha-PHP, MPHP, U-49900, U-48800/U-51754, m/p- Methylmethoxyacetylfentanyl, p,o-Fluorofentanyl, and Tetrahydrofuranfentanyl as compounds that may be detected in forensic cases. In situations where NMS Labs may detect the presence of these compounds, the client will be notified and may consult with us on next steps given the case history and testing capabilities at the time. At NMS Labs, we are dedicated and proactive in identifying NPS in response to the latest information uncovered in our forensic death investigative work to provide our clients with greater awareness and identification of the drugs most relevant to public health and safety. As such, this list of compounds will be dynamic.

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