Medicaid Provider Manual

Total Page:16

File Type:pdf, Size:1020Kb

Medicaid Provider Manual MHS Health Wisconsin Medicaid Provider Manual MHS Health Wisconsin© 1 February, 2016 Introductory Information - MHS Health at-a-Glance .............................................................................................................. 3 MHS Health Wisconsin History ............................................................................................................................................... 5 Section 1 Secure Provider Portal ............................................................................................................................................ 7 • Registration on the portal • Changing Provider information on the portal Section 2 Other Resources for Network Providers ................................................................................................................. 9 • Quick Reference Guide Section 3 Guidelines for Providers ........................................................................................................................................ 13 • PCP, Specialist and hospital responsibilities • Reporting requirements Section 4 Quality Improvement Program ............................................................................................................................. 20 Section 5 Medical Records .................................................................................................................................................... 24 Section 6 Eligibility Verification/Member Enrollment .......................................................................................................... 26 Section 7 Routine, Urgent and Emergent Services ............................................................................................................... 28 Section 8 Covered Services ................................................................................................................................................... 30 Section 9 Health Check ......................................................................................................................................................... 33 Section 10 Medical Management ......................................................................................................................................... 36 • Authorization requirements • Services which do not require authorization Section 11 Pharmacy Benefit ................................................................................................................................................ 49 Section 12 Billing Information and Guidelines ...................................................................................................................... 50 • Claims submission and claim forms • EDI claims and EFT information • Payment protocol • Claim form completion guidelines • Emergency Department hospital claims adjudication process Section 13 Provider Complaints, Grievances and Appeals ................................................................................................... 97 Section 14 Member Services ............................................................................................................................................... 102 • Member complaints and grievances Section 15 Provider Credentialing ...................................................................................................................................... 108 Section 16 Transportation................................................................................................................................................... 112 2 Introductory Information - MHS Health at-a-Glance MHS Health Wisconsin and Network Health Plan Electronic Claim Submission More than 10,000 clinicians and 90 hospitals service MHS Clearinghouses and payor IDs: For all Health and Network Health Plan (NHP) members through MHS Health and NHP claims for the below BadgerCare Plus, Medicaid SSI, and Medicare Advantage - payors - 68069 Special Needs Plan (SNP), and our Ambetter from MHS Availity Allscripts/Payorpath Capario Health Wisconsin commercial plans. Claim Remedi Claimsource CPSI Location DeKalb First Health Care GatewayEDI MHS Health Wisconsin GHNonline IGI McKesson 10700 W. Research Dr., Suite 300, Milwaukee, WI 53226 MDonLine Physicians CC Practice Insight Smarta Data SSI Viatrack MHS Provider Inquiry Line RelayHealth Using Interactive Voice Recognition (IVR), check the (NDC/per Se) following: • Eligibility Provider Inquiry Line Emdeon WebMD Envoy • Claims information MHS/NHP.............................................. 39187 • 1-800-222-9831 Benefits Managed Health Services Advantage ...68056 • Authorization status Networks MHS/NHP/Advantage........... 96822 • Authorization requests Please have your NPI or Tax Identification Number or the member’s Medicaid ID number. Paper Claim Submission and Correction MHS Health Wisconsin Medical Services FAX lines: Attn: Claims Department P.O. Box 3001 Prior authorization requests: Farmington, MO 63640-3801 866-467-1316 Notification of Pregnancy Form: 866-681-5125 Refund Overpayment (on Provider check stock) MHS Health Wisconsin NurseWise® 24-hour Nurse Advice Line 6417 Paysphere Circle Chicago, IL 60674-6417 800-280-2348 Return checks Behavioral Health - Cenpatico 800-589-3186 MHS Health Wisconsin Attn: Returned Checks PO Box 3001 Pharmacy Benefit for Medicaid only Farmington, MO 63640-3801 For Medicaid, please bill the following as fee-for-service to the State: Prescription drugs, radiopharmaceuticals, To request a review of a “medical code denial” injectable biopharmaceuticals and other injectables MHS Health Wisconsin administered in a home health facility, an MD office, a Attn: Medical Review Unit skilled nursing facility, and most outpatient environments. PO Box 3001 Farmington, MO 63640-3800 Visit the website at www.mhswi.com to: Administrative Claim Appeal • Obtain a list of MHS Health and NHP patients and their MHS Health Wisconsin benefit and eligibility details, including other insurance, Attn: Appeals Department member care gaps, PCP and eligibility history. PO Box 3000 • Search for network Providers (updated weekly) Farmington, MO 63640-3800 • Submit and view authorizations Medical Necessity Claim Appeal • Use code-auditing software MHS Health Wisconsin • Submit claims including other insurance payment Attn: Medical Necessity Appeals • Export, download and check claim status, payment 10700 W. Research Dr., Suite 300 history, payment amounts & dates which are updated Milwaukee, WI 53226 every 24 hours Member Services- 888-713-6180 3 MHS Health and NHP refers to the BadgerCare Plus, Medicaid SSI members of MHS Health Wisconsin and Network Health Plan 4 MHS Health Wisconsin History MHS Health Wisconsin is one of the State’s oldest Medicaid plans, created in 1984, solely to manage the healthcare of the Medicaid population. Today, the MHS Health network consists of more than 10,000 clinicians and 94 hospitals. We serve our members through these programs: • BadgerCare Plus • BadgerCare Plus Childless Adults Program • Medicaid SSI • Medicare Advantage, Special Needs Plan (SNP) • Ambetter Marketplace Plan MHS Health Wisconsin is a wholly-owned subsidiary of Centene Corporation, St. Louis, MO. Centene Corporation, a Fortune 500 company, is a diversified, multi-national healthcare enterprise that provides a portfolio of services to government-sponsored healthcare programs, focusing on under-insured and uninsured individuals. The Company operates local health plans and offers a range of health insurance solutions. It also contracts with other healthcare and commercial organizations to provide specialty services including behavioral health management, care management software, correctional healthcare services, dental benefits management, in-home health services, life and health management, managed vision, pharmacy benefits management, specialty pharmacy and tele health services. Our beliefs MHS Health Wisconsin believes that successful managed care is the delivery of appropriate, medically necessary services and not the elimination of such services. We believe in providing healthcare that is managed by a local team to conveniently service your needs. Our philosophy is to provide access to high-quality, culturally-sensitive healthcare services to our members. We do so by combining the talents of primary care Providers and specialty Providers with an experienced, highly successful managed care administrator. We take privacy seriously At MHS Health Wisconsin, we take the privacy and confidentiality of our members’ health information seriously. We have processes, policies and procedures that comply with the Health Insurance Portability and Accountability Act of 1996 (HIPAA), the HITECH amendment to HIPAA and State privacy law requirements. HIPAA does permit Providers to share information such as telephone numbers, addresses and so forth when such information is in regard to a current member. This is considered part of treatment, payment, and health care operations and is allowable under HIPAA. It is the policy of MHS Health Wisconsin to conduct its business affairs in accordance with the standards and rules of ethical business conduct and to abide by all applicable federal and State laws. If you have any questions about our privacy practices, please call the MHS compliance officer at: 1-800-222-9831. MHS Health and Betty Brinn MHS Health Wisconsin and the market have changed in many ways since 1984. Yet, we are essentially the same organization that Maxicare Health
Recommended publications
  • Centene Completes Acquisition of Wellcare, Creating a Leading Healthcare Enterprise Focused on Government- Sponsored Healthcare Programs
    January 23, 2020 Centene Completes Acquisition of WellCare, Creating a Leading Healthcare Enterprise Focused on Government- Sponsored Healthcare Programs ST. LOUIS, Jan. 23, 2020 /PRNewswire/ -- Centene Corporation (NYSE: CNC) ("Centene") announced today that it has completed its acquisition of WellCare Health Plans, Inc. ("WellCare"). Centene now provides access to high-quality and affordable healthcare to its more than 24 million members across all 50 states, or 1 in 15 individuals across the nation. The Company will continue to place great emphasis on long-term growth by prioritizing its people, systems and capabilities so that it can better serve its members, providers and government partners. "We are pleased to have completed this transformational acquisition to create a leading healthcare enterprise committed to helping people live healthier lives through access to high- quality and affordable healthcare solutions," said Michael F. Neidorff, Centene's Chairman, President and Chief Executive Officer. "Through the integration planning process, it has become even more apparent that our goals, cultures and values are aligned. Centene is committed to building on our mission to further improve the health of the communities we serve. We look forward to Centene's next chapter where we will continue to drive growth and create value for shareholders." Pursuant to the terms of the merger agreement, as announced on March 27, 2019, WellCare became a wholly owned subsidiary of Centene. Under the terms of the merger agreement, WellCare shareholders received a fixed exchange ratio of 3.38 shares of Centene common stock and $120 in cash for each share of WellCare common stock. With the completion of the transaction, the previously announced divestitures of Centene's Illinois Medicaid and Medicare Advantage plans, WellCare's Missouri Medicaid and Medicare Advantage plans and WellCare's Nebraska Medicaid plan have also closed.
    [Show full text]
  • Business Ethics and Conduct Policy a GUIDE to CONDUCT in the WORKPLACE
    Business Ethics and Conduct Policy A GUIDE TO CONDUCT IN THE WORKPLACE BUSINESS ETHICS AND CONDUCT POLICY | 1 Dear Employee, Since its foundation in 1984, Centene has built an honorable reputation and an exceptional culture through the hard work and integrity of its employees. We have achieved significant growth and success by upholding this reputation and acting with the highest values and principles. We will continue to succeed if we all work to understand the values contained in this Code of Conduct and direct our individual behavior by them. This guide was established to shape, illustrate and defend the values that each employee is expected to uphold. The purpose of this guide is to help you choose wisely when you represent Centene and its subsidiaries to others, as well as when dealing with your fellow workers. Every decision you make, every action you take, can affect employee morale, the perception of our company and the sustainable results we achieve. Each of us are integral to the company’s reputation, and Centene holds employees accountable to always take personal responsibility to choose what is right. Our company’s success depends on a reputation for integrity and high ethical standards in everything we do. Thank you for reading and understanding and adhering to the code of conduct contained within this guide. Michael F. Neidorff Chairman, President and Chief Executive Officer A SOLID COMMITMENT Table of Contents About the Code of Conduct 5 Antitrust & Competition 12 Financial Records & Controls 14 Fraud and Abuse 16 Inside Information 20 Trade Secrets & Confidential Information 22 Media Relations 24 Ethics & Electronic Communications 28 Compliance Helpline Conflicts of Interest 30 To report suspected violations of Gifts and Bribes 32 the code or seek advice regarding a Political Activities 34 specific situation call: Healthcare Laws 38 1-800-345-1642 (toll-free) Harassment & Discrimination 40 Enterprise Risk Management 42 Waivers 43 or go to Reporting Procedures 44 www.mycompliancereport.
    [Show full text]
  • View Annual Report
    30 Years of Excellence 2014 annual review As we commemorate our 30th year of service, our commitment to quality healthcare with dignity has never wavered. 30 years of exCELLENCE TABLE OF CONTENTS Centene Corporation is a diversified, multi-national 1 2014 at a Glance 3 Letter from the Chairman healthcare enterprise that provides a portfolio of 6 Company and Financial Summary services to government-sponsored healthcare programs, 7 Nationwide Presence 8 2014 Highlights focusing on under-insured and uninsured individuals. 10 30 Years of Transformation Centene offers unique, cost-effective coverage solutions 12 Continuum of Care 14 The Growing Sophistication for low-income populations through locally based of Healthcare health plans and a wide range of specialty services. 15 Technology for More Personalized Care 16 Clinical Programs Reflecting Founding Beliefs 17 Focus on the Member 18 Quarterly Financial Information 19 Selected Financial Information 20 Corporate Information 2014 aT A GLANCE 56 percent increase in diluted earnings per common share $15.7 billion (from continuing operations) premium and service revenues $1.2 billion total operating cash flow 4.1 million managed care membership 13,400 employees 76 percent stock price growth in 2014 LEttER FROM THE CHAIRMAN For over 30 years, Centene Corporation’s Centene’s growth is a testament to our strategies of steadfast devotion to our founding values and beliefs diversification, financial discipline and successful execution. Moreover, our deep commitment to the members, clients has driven our company’s success. From our humble and communities we serve continue to shape our success. beginnings as a nonprofit Medicaid pilot in Milwaukee, In 2014, Centene’s membership grew 41 percent to 4.1 million managed care members, while premium and service revenue Centene has grown to a multibillion dollar enterprise, grew 49 percent to $15.7 billion.
    [Show full text]
  • TRICARE® Provider Resources
    ® TRICARE W Provider Resources A Wholly-Owned Subsidiary of Centene Corporation Health Net Federal Services, LLC (HNFS) Resources Resource Services Provided A secure portal for TRICARE transactions: • Verify eligibility (plan type, copayments/cost-shares, deductibles, catastrophic cap, other health insurance) • Submit authorization and referral requests, and check status • Notify HNFS of inpatient hospital admissions • Use XPressClaim® to electronically submit claims • Submit claims-related supporting documentation • Sign up for electronic remittance advice statements and electronic funds transfer • Check claims status and view claims data reports for all your TRICARE patients • Make demographic and provider specialty updates • Access primary care manager (PCM) panel “PCM Enrollee Roster” information • View patient medication lists and Prescription Monitoring Program status • Send secure electronic mail through Ask Us www.tricare-west.com • Access your Secure Inbox A public portal with interactive tools: • View HNFS’ West Region Network, Non-Network and Mental Health Care Provider Directories • Submit authorization and referral requests, and check status (no log in option) • Verify eligibility (no log in option) • Determine prior authorization and referral requirements based on beneficiary status and plan type • View the Benefits A–Z and copayment/cost-share guides • Access provider resources: TRICARE Provider Handbook, TRICARE Provider News newsletter, provider webinar schedule, forms, FAQs, and more • Find links to the TRICARE CHAMPUS
    [Show full text]
  • Sunshine Health Is a Managed Care Organization (MCO) Contracted With
    Sunshine Health is a Managed Care Organization (MCO) contracted with the Florida Agency for Health Care Administration (AHCA) to serve Medicaid and other government services program members. Sunshine Health has developed the expertise to work with Medicaid members to improve their health status and quality of life. Our number one priority is the promotion of healthy lifestyles through preventive healthcare. Sunshine Health works to accomplish this goal by partnering with the Primary Care Providers (PCPs) who oversee the healthcare of Sunshine Health members. Medicaid is the state and federal partnership that provides health coverage for selected categories of people with low incomes. Its purpose is to improve the health of people who might otherwise go without medical care for themselves and their children. Medicaid is different in every state. Sunshine Health is a wholly owned subsidiary of Centene Corporation which provides Medicaid managed care services to members in designated counties of Florida. Centene and its wholly owned health plans have a long and successful track record offering Medicaid managed care services. For more than 20 years, Centene has provided comprehensive managed care services to the Medicaid population and currently operates health plans in Georgia, Indiana, Ohio, Massachusetts, South Carolina, Texas, Mississippi, and Wisconsin. Sunshine Health serves our Florida members consistent with our core philosophy that quality healthcare is best delivered locally. Sunshine Health is a physician-driven organization that
    [Show full text]
  • Centene's Missouri Subsidiary Announces Successful
    CENTENE’S MISSOURI SUBSIDIARY ANNOUNCES SUCCESSFUL REPROCUREMENT OF MANAGED CARE CONTRACT ST. LOUIS (March 3, 2015) —Centene Corporation (NYSE: CNC) today announced the Missouri Division of Purchasing and Materials Management has selected its Missouri subsidiary, Home State Health, to continue providing managed care services to MO HealthNet Managed Care beneficiaries. Under the new contract, Home State Health will serve MO HealthNet Managed Care families and children in 54 counties, commencing July 1, 2015. “Home State Health is pleased to continue our work in Missouri, collaborating and engaging with local providers to align innovative programs designed to transform the health of the communities we serve,” said Shannon Bagley, Home State President and CEO. “We have developed partnerships in the community that help simplify the health care experience and empower our members to engage in support systems that were once beyond their reach.” “We look forward to continuing our work with the state and the healthcare providers in our network to improve health outcomes and reduce the cost of healthcare delivery in Missouri,” said K. Rone Baldwin, Executive Vice President, Insurance Group at Centene. “Home State Health’s focus on wellness, prevention, early detection and ongoing health management has resulted in healthier families and children in Missouri.” Since inception in 2012, Home State Health’s membership increased by more than 45% and its network of providers has grown to over 14,000 primary care physicians and specialists. Centene employs more than 2,000 in Missouri and has 10 separate office locations throughout the state, including a new claims processing center in Ferguson and two Home State Health office locations in Chesterfield and Jefferson City.
    [Show full text]
  • Clinical Policy
    Clinical Policy: Lumasiran (Oxlumo) Reference Number: CP.PHAR.473 Effective Date: 11.23.20 Last Review Date: 02.21 Coding Implications Line of Business: Commercial, HIM, Medicaid Revision Log See Important Reminder at the end of this policy for important regulatory and legal information. Description Lumasiran (Oxlumo™) is an RNAi therapeutic targeting glycolate oxidase (GO). FDA Approved Indication(s) Oxlumo is indicated for the treatment of primary hyperoxaluria type 1 (PH1) to lower urinary oxalate levels in pediatric and adult patients . Policy/Criteria Provider must submit documentation (such as office chart notes, lab results or other clinical information) supporting that member has met all approval criteria. It is the policy of health plans affiliated with Centene Corporation® that Oxlumo is medically necessary when the following criteria are met: I. Initial Approval Criteria A. Primary Hyperoxaluria Type 1 (must meet all): 1. Diagnosis of PH type 1 confirmed by one of the following (a or b): a. Genetic testing confirming presence of mutations in the AGXT gene; b. Liver biopsy confirming AGT enzyme deficiency; 2. Prescribed by or in consultation with an endocrinologist, hepatologist, or nephrologist; 3. Documentation of one of the following (a or b): a. Urinary oxalate (UOx) excretion > 0.70 mmol/1.73 m2/24 h, confirmed on repeat testing; b. Spot urinary oxalate-to-creatinine (UOx:Cr) molar ratio greater than normal for age (see Appendix D for reference ranges), confirmed on repeat testing; 4. Documentation of estimated glomerular filtration rate (eGFR) > 30 mL/min/1.73 m2; 5. Failure of at least three months of pyridoxine (vitamin B6) at up to maximally indicated doses, unless contraindicated or clinically significant adverse effects are experienced; *Failure is defined as not achieving a >30% reduction in urinary oxalate excretion after a minimum of 3 months at maximum dose.
    [Show full text]
  • 2020 ESHG Report to the Community (PDF)
    Environmental, Social, Health, and Governance Report to the Community 2020 LETTER FROM THE CHAIRMAN MICHAEL F. NEIDORFF Chairman, President, & Chief Executive Officer As the leader in government-sponsored healthcare, we understand that our role in serving our members has never been more essential — particularly as we consider the impact of COVID-19 Centene is a multi-national healthcare enterprise founded in 1984 on the belief that everyone deserves access to affordable, quality and pressing issues across the country. healthcare with dignity. Centene holds a unique position to Today, we offer a comprehensive portfolio of innovative health solutions to more than 25 million members, across all 50 states and address the environmental, social, and internationally, that help members get, and stay, healthy. At the health barriers that impact our most intersection of Centene’s growth and our impact on communities, exists our core beliefs and values. Center to those values is our vulnerable populations. Supported by commitment to remove barriers to health and invest in local partnerships. In adherence to that commitment, Centene launched a a culture of sound corporate range of initiatives and programs that address specific community challenges through collaborations with governments, healthcare, and governance, our commitment to the community partners. secure and responsible management of information and data remains strong. Our progress toward improving healthcare access, quality, and affordability TABLE OF CONTENTS continued in 2020. To address the increased rate of infections and deaths from COVID-19 impacting communities of color, Centene and the National Minority 1 Letter from the Chairman Quality Forum (NMQF) partnered to assess COVID-19’s impact on racial 4 Environmental, Social, Health, and Governance Oversight minorities and rural communities.
    [Show full text]
  • Medicaid Managed Care Savings Meta-Review
    wakely.com Centene Corporation Medicaid Managed Care Savings Meta-Review June 15, 2020 Prepared by: Wakely Consulting Group, LLC Taylor Pruisner, FSA, MAAA Director and Senior Consulting Actuary Sam Rickert, FSA, MAAA Senior Consulting Actuary Ryan Link, FSA, MAAA Consulting Actuary page i Table of Contents Executive Summary ........................................................................................................ 1 Background, Definitions, and Programmatic History ....................................................... 2 Methodology, Assumptions, and Results ........................................................................ 5 Disclosures and Limitations ............................................................................................. 7 Medicaid Managed Care Savings Meta-Review Centene Corporation Page 1 Executive Summary This report summarizes the results from Wakely’s recent analyses of achieved programmatic savings in four different state Medicaid managed care programs. In each analysis, the capitation rates net of premium taxes were compared to estimated costs for those same members if they had been covered by traditional fee for service (FFS) Medicaid. Across four Medicaid managed care programs encompassing a total of 30 rating years, Wakely found significant, and increasing, savings relative to estimated costs under a FFS program. These programmatic savings, taken with the ability to generate additional federal funding through premiums taxes, indicate that Medicaid managed care programs offer states
    [Show full text]
  • FACT SHEET: CENTENE CORPORATION General Context
    FACT SHEET: CENTENE CORPORATION General Context More than half of all Medicaid beneficiaries nationally receive most or all of their care from risk-based managed care organizations (MCOs) that contract with state Medicaid programs to deliver comprehensive Medicaid services to enrollees. Although not all state Medicaid programs contract with MCOs, a large and growing majority do, and states are also rapidly expanding their use of MCOs to reach larger geographic areas, serve more medically complex beneficiaries, deliver long-term services and supports, and, in states that have expanded Medicaid under the Affordable Care Act (ACA), to serve millions of newly eligible low-income adults. Total Medicaid MCO spending in the US (FY2014) was $162B, which comprised 34% of total Medicaid spending.1 Centene 1. Centene Corporation, a publically traded Fortune 500 company (#186), is a diversified, multi-national healthcare enterprise that provides a portfolio of services to government sponsored healthcare programs, focusing on under- insured and uninsured individuals. Centene (ticker: CNC) operates in 25 states2 and as of March 2016, provides Medicaid MCO services in 17 states.3 However, Centene is only providing Medicaid MLTSS in Arizona, Texas, and Georgia.4 2. Centene also operates in integrated care programs in Florida and Ohio. 3. Centene reports that its 2015 revenues were $21.3B, earnings were $356M, and $7.3M in total assets.5 4. In Centene Corporation’s 2015 annual report, they sought to increase managed care membership in the U.S. The report expressed that managed care membership increased by 5.1 million members. The report also highlights Centene’s interest in expanding access to underserved populations including Medicaid/CHIP (150,000 enrollees,) Foster Care (83,000 enrollees,) Medicare (One Special Needs Plan,) LTSS and I/DD (75,000 enrollees.)6 5.
    [Show full text]
  • Impact of Proposed Acquisition of Wellcare by Centene
    ASIPP® FACT SHEET 2019 Impact of Proposed Acquisition of Wellcare by Centene KEY POINTS 1. The Centene Corporation acquisition of WellCare is disastrous to the entire medical community but would be particularly impactful on interventional pain management where we have seen patients denied access to most pain management procedures leading to escalating opioid usage due to lack of non-opioid treatments. 2. If Centene Corp is able to buy Wellcare, the company would be cementing its position atop the Medicaid managed-care market. 3. A combined Cente-Wellcare would more than double Centene’s Medicare Advantage membership. As we have revealed to you, Medicare Advantage is having substantial issues, specifically with Centene and Wellcare. 4. The Justice Department successfully blocked a merger between Aetna and Humana, and another between Anthem and Cigna, saying the combination would reduce competition. 5. Centene serves about 2 million Affordable Care Act exchange members in 22 states - the most of any insurer, yet their quality of the services they provide are the worst with top payment for the executive team and minimum payments to patients and providers. REQUESTED ACTIONS On behalf of the American Society of Interventional Pain Physicians (ASIPP), the North American Neuromoducation Society (NANS), and the Society of Interventional Pain Management Surgery Centers (SIPMS), we are rquesting Congress to ask the Department of Justice to look into Centene’s proposed $17 billion acquisition of Wellcare. This merger will drastically and adversely affect interventional pain management, and could even lead to the end of interventional pain management for not only Medicaid patients but also dual eligible Medicare.
    [Show full text]
  • Clinical Policy: Inebilizumab-Cdon (Uplizna)
    Clinical Policy: Inebilizumab-cdon (Uplizna) Reference Number: CP.PHAR.458 Effective Date: 09.10.20 Last Review Date: 09.20 Coding Implications Line of Business: WellCare Medicaid Revision Log See Important Reminder at the end of this policy for important regulatory and legal information. Description Inebilizumab-cdon (Uplizna ™) is an anti-CD19 monoclonal antibody. FDA Approved Indication(s) Uplizna is indicated for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in adult patients who are anti-aquaporin-4 (AQP4) antibody positive. Policy/Criteria Provider must submit documentation (such as office chart notes, lab results or other clinical information) supporting that member has met all approval criteria. It is the policy of health plans affiliated with Centene/WellCare Corporation® that Uplizna is medically necessary when the following criteria are met: I. Initial Approval Criteria A. Neuromyelitis Optica Spectrum Disorder (must meet all): 1. Diagnosis of NMOSD; 2. Prescribed by or in in consultation with a neurologist; 3. Age ≥ 18 years; 4. Member has positive serologic test for anti-AQP4 antibodies; 5. Member has experienced at least one relapse within the previous 12 months; 6. Member meets one of the following (a or b): a. History of at least one relapse requiring rescue therapy† during the previous 12 months; b. History of two relapses requiring rescue therapy† during the previous 24 months; † Rescue therapies include: IV corticosteroids, IV immunoglobulin, and/or plasma exchange 7. Baseline expanded disability status scale (EDSS) score of ≤ 8; 8. Failure of rituximab (Ruxience™ and Truxima® are preferred) at up to maximally indicated doses, unless contraindicated or clinically significant adverse effects are experienced; *Prior authorization may be required for rituximab 9.
    [Show full text]