CARNEGIE/DOE ALLIANCE CENTER Year Four Annual Report
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Brillouin Imaging for Studies of Micromechanics in Biology and Biomedicine: from Current State-Of-The-Art to Future Clinical Translation
Brillouin imaging for studies of micromechanics in biology and biomedicine: from current state-of-the-art to future clinical translation Christine Poon1,2, Joshua Chou2, Michael Cortie1 and Irina Kabakova1* 1 School of Mathematical and Physical Sciences, Faculty of Science, University of Technology Sydney, Ultimo 2007, Australia 2School of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney, Ultimo 2007, Australia *corresponding author: [email protected] Abstract: Brillouin imaging is increasingly recognized to be a powerful technique that enables non- invasive measurement of the mechanical properties of cells and tissues on a microscopic scale. This provides an unprecedented tool for investigating cell mechanobiology, cell-matrix interactions, tissue biomechanics in healthy and disease conditions and other fundamental biological questions. Recent advances in optical hardware have particularly accelerated the development of the technique, with increasingly finer spectral resolution and more powerful system capabilities. We envision that further developments will enable translation of Brillouin imaging to assess clinical specimens and samples for disease screening and monitoring. The purpose of this review is to summarize the state- of-the-art in Brillouin microscopy and imaging with a specific focus on biological tissue and cell measurements. Key system and operational requirements will be discussed to facilitate wider application of Brillouin imaging along with current challenges for translation -
Elastic Characterization of Transparent and Opaque Films, Multilayers and Acoustic Resonators by Surface Brillouin Scattering: a Review
applied sciences Article Elastic Characterization of Transparent and Opaque Films, Multilayers and Acoustic Resonators by Surface Brillouin Scattering: A Review Giovanni Carlotti ID Dipartimento di Fisica e Geologia, Università di Perugia, 06123 Perugia, Italy; [email protected]; Tel.: +39-0755-852-767 Received: 17 December 2017; Accepted: 5 January 2018; Published: 16 January 2018 Abstract: There is currently a renewed interest in the development of experimental methods to achieve the elastic characterization of thin films, multilayers and acoustic resonators operating in the GHz range of frequencies. The potentialities of surface Brillouin light scattering (surf-BLS) for this aim are reviewed in this paper, addressing the various situations that may occur for the different types of structures. In particular, the experimental methodology and the amount of information that can be obtained depending on the transparency or opacity of the film material, as well as on the ratio between the film thickness and the light wavelength, are discussed. A generalization to the case of multilayered samples is also provided, together with an outlook on the capability of the recently developed micro-focused scanning version of the surf-BLS technique, which opens new opportunities for the imaging of the spatial profile of the acoustic field in acoustic resonators and in artificially patterned metamaterials, such as phononic crystals. Keywords: acousto-optics at the micro- and nanoscale; photon scattering by phonons; elastic constants of films and multilayers 1. Introduction The problem of a detailed knowledge of the elastic constants of thin film materials has attracted much attention in recent years, because of the growing importance of single- and multi-layered structures in advanced applications such as in devices for information and communication technology (ICT). -
Best Celeb Video
DAILY STAR SUNDAY, June 25, 2017 19 Euan enlists celebs for ultimate wedding video ■ EXCLUSIVE by EMILY HALL [email protected] A BEST man spent two years asking stars to record good luck messages for a happy couple. Formula One racer Jenson FORTUNE: The KLF Button and Doctor Who actor Matt Lucas were among the big names who joined in the fun. £1m KLF Euan Gibson sent out more BEST MAN’S than 2,000 requests to A-listers including George Clooney, cash ‘not David Beckham and Brad Pitt. He even sent Barack Obama 200 emails asking the former US President to do a cameo in lost in fi re’ the video for his best pal Tim Hockley, who married girl- BARMY band The KLF friend Charlotte Baker in salvaged every penny of France last weekend. the £1million they famously Guests were amazed by the burned as a stunt because video, played at the reception, the metallic silver strips on featuring funnyman Jason STAR TURN the notes stayed intact. Manford, 36, and Dom Joly, 49, The group wanted to make and sports presenter Gabby a statement against capital- Logan, 44. ism by torching everything Radio host and Strictly star they had earned from hits Jeremy Vine, 52, sent footage like Justifi ed And Ancient, from the dance fl oor and Alan 3am Eternal and What Fletcher, 60 inset below – Karl Time Is Love after deleting Kennedy in Neighbours – joked their entire back catalogue he loved weddings as he was of songs. married to Susan three times Founder members Bill in the soap. -
The British Academy Television Awards Sponsored by Pioneer
The British Academy Television Awards sponsored by Pioneer NOMINATIONS ANNOUNCED 11 APRIL 2007 ACTOR Programme Channel Jim Broadbent Longford Channel 4 Andy Serkis Longford Channel 4 Michael Sheen Kenneth Williams: Fantabulosa! BBC4 John Simm Life On Mars BBC1 ACTRESS Programme Channel Anne-Marie Duff The Virgin Queen BBC1 Samantha Morton Longford Channel 4 Ruth Wilson Jane Eyre BBC1 Victoria Wood Housewife 49 ITV1 ENTERTAINMENT PERFORMANCE Programme Channel Ant & Dec Saturday Night Takeaway ITV1 Stephen Fry QI BBC2 Paul Merton Have I Got News For You BBC1 Jonathan Ross Friday Night With Jonathan Ross BBC1 COMEDY PERFORMANCE Programme Channel Dawn French The Vicar of Dibley BBC1 Ricky Gervais Extra’s BBC2 Stephen Merchant Extra’s BBC2 Liz Smith The Royle Family: Queen of Sheba BBC1 SINGLE DRAMA Housewife 49 Victoria Wood, Piers Wenger, Gavin Millar, David Threlfall ITV1/ITV Productions/10.12.06 Kenneth Williams: Fantabulosa! Andy de Emmony, Ben Evans, Martyn Hesford BBC4/BBC Drama/13.03.06 Longford Peter Morgan, Tom Hooper, Helen Flint, Andy Harries C4/A Granada Production for C4 in assoc. with HBO/26.10.06 Road To Guantanamo Michael Winterbottom, Mat Whitecross C4/Revolution Films/09.03.06 DRAMA SERIES Life on Mars Production Team BBC1/Kudos Film & Television/09.01.06 Shameless Production Team C4/Company Pictures/01.01.06 Sugar Rush Production Team C4/Shine Productions/06.07.06 The Street Jimmy McGovern, Sita Williams, David Blair, Ken Horn BBC1/Granada Television Ltd/13.04.06 DRAMA SERIAL Low Winter Sun Greg Brenman, Adrian Shergold, -
Elastic Properties of Taurine Single Crystals Studied by Brillouin Spectroscopy
International Journal of Molecular Sciences Article Elastic Properties of Taurine Single Crystals Studied by Brillouin Spectroscopy Dong Hoon Kang 1, Soo Han Oh 1, Jae-Hyeon Ko 1,* , Kwang-Sei Lee 2 and Seiji Kojima 3 1 Nano Convergence Technology Center, School of Nano Convergence Technology, Hallym University, 1 Hallymdaehakgil, Chuncheon 24252, Korea; [email protected] (D.H.K.); [email protected] (S.H.O.) 2 Center for Nano Manufacturing, Department of Nano Science & Engineering, Inje University, Gimhae 50834, Korea; [email protected] 3 Division of Materials Science, University of Tsukuba, Tsukuba 305-8573, Japan; [email protected] * Correspondence: [email protected]; Tel.: +82-33-248-2056 Abstract: The inelastic interaction between the incident photons and acoustic phonons in the taurine single crystal was investigated by using Brillouin spectroscopy. Three acoustic phonons propagating along the crystallographic b-axis were investigated over a temperature range of −185 to 175 ◦C. The temperature dependences of the sound velocity, the acoustic absorption coefficient, and the elastic constants were determined for the first time. The elastic behaviors could be explained based on normal lattice anharmonicity. No evidence for the structural phase transition was observed, consistent with previous structural studies. The birefringence in the ac-plane indirectly estimated from the split longitudinal acoustic modes was consistent with one theoretical calculation by using the extrapolation of the measured dielectric functions in the infrared range. Citation: Kang, D.H.; Oh, S.H.; Ko, Keywords: taurine; elastic constant; Brillouin scattering; acoustic mode J.-H.; Lee, K.-S.; Kojima, S. Elastic Properties of Taurine Single Crystals Studied by Brillouin Spectroscopy. -
Temperature Dependence of Brillouin Light Scattering Spectra of Acoustic Phonons in Silicon Kevin S
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by UT Digital Repository Temperature dependence of Brillouin light scattering spectra of acoustic phonons in silicon Kevin S. Olsson, Nikita Klimovich, Kyongmo An, Sean Sullivan, Annie Weathers, Li Shi, and Xiaoqin Li Citation: Applied Physics Letters 106, 051906 (2015); doi: 10.1063/1.4907616 View online: http://dx.doi.org/10.1063/1.4907616 View Table of Contents: http://scitation.aip.org/content/aip/journal/apl/106/5?ver=pdfcov Published by the AIP Publishing Articles you may be interested in Off-axis phonon and photon propagation in porous silicon superlattices studied by Brillouin spectroscopy and optical reflectance J. Appl. Phys. 116, 033510 (2014); 10.1063/1.4890319 Raman-Brillouin scattering from a thin Ge layer: Acoustic phonons for probing Ge/GeO2 interfaces Appl. Phys. Lett. 104, 061601 (2014); 10.1063/1.4864790 Brillouin light scattering spectra as local temperature sensors for thermal magnons and acoustic phonons Appl. Phys. Lett. 102, 082401 (2013); 10.1063/1.4793538 Acoustics at nanoscale: Raman–Brillouin scattering from thin silicon-on-insulator layers Appl. Phys. Lett. 97, 141908 (2010); 10.1063/1.3499309 Mechanical properties of diamond films: A comparative study of polycrystalline and smooth fine-grained diamonds by Brillouin light scattering J. Appl. Phys. 90, 3771 (2001); 10.1063/1.1402667 This article is copyrighted as indicated in the article. Reuse of AIP content is subject to the terms at: http://scitation.aip.org/termsconditions. Downloaded to IP: 128.83.205.53 On: Mon, 27 Jul 2015 18:08:39 APPLIED PHYSICS LETTERS 106, 051906 (2015) Temperature dependence of Brillouin light scattering spectra of acoustic phonons in silicon Kevin S. -
Ebook Download Little Britain, Best of TV Series 2 Pdf Free Download
LITTLE BRITAIN, BEST OF TV SERIES 2 PDF, EPUB, EBOOK Matt Lucas | none | 03 Oct 2005 | BBC Audio, A Division Of Random House | 9781846070594 | English | London, United Kingdom Little Britain, Best of TV Series 2 PDF Book Oh for f- rickygervais. This website uses cookies to improve your experience. Come On Down! We made a more cruel kind of comedy than I'd do now. Kimberly: What, yes, you know, or yes, there are nuts? The intimidated shopkeeper claims he is on his lunh hour and so calls for his wife to serve him, but she refuses claiming she "has no arms or legs. Happy birthday. Hello, Mr. Subscribe to: Post Comments Atom. The card is for a year-old. More on this story. Walliams has also said he would "definitely do it differently" in today's cultural landscape. With a glass eye. Please enter a valid email address. Keith Lemon actor sorry for playing 'offensive' black characters. Yes, Meera. Which she thin sips elegantly. You said it was the last bastion of moral cowardice. Mike: Well, which? Made in Chelsea is low-brow TV at its finest. Metacritic Reviews. Title: Little Britain — More You Might Like. For your security, we've sent a confirmation email to the address you entered. Featured Post. Her sketch is rumoured to include a Zoom parish meeting, which will no doubt be doomed to technical failure. Meera 20 episodes, Little Britain USA. If you don't get the confirmation within 10 minutes, please check your spam folder. Our massive preview has details on the most promising new shows and your Some of the shows pulled from streaming services were made by household names here. -
Surface Brillouin Scattering in Opaque Thin Films and Bulk Materials
SURFACE BRILLOUIN SCATTERING IN OPAQUE THIN FILMS AND BULK MATERIALS Clemence Sumanya A thesis submitted to the Faculty of Science, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Doctor of Philosophy. Johannesburg, 2012 ii Abstract Room temperature elastic properties of thin supported TiC films, deposited on silicon and silicon carbide substrates and of single Rh-based alloy crystals, Rh 3Nb and Rh 3Zr, are investigated by the Surface Brillouin Scattering (SBS) technique. Velocity dispersion curves of surface acoustic waves in TiC films of various thicknesses, deposited on each substrate (Si and SiC) were obtained from SBS spectra. Simulations of SBS spectra of TiC thin hard films on germanium, silicon, diamond and silicon substrates have been carried out over a range of film thickness from 5 nm to 700 nm. The simulations are based on the elastodynamic Green's functions method that predicts the surface displacement amplitudes of acoustic phonons. These simulations provide information essential for analysis of experimental data emerging from SBS experiments. There are striking differences in both the simulated and experimental SBS spectra depending on the respective elastic properties of the film and the substrate. In fast on slow systems (e.g. TiC on silicon), the Rayleigh mode is accompanied by both broad and sharp resonances; in slow on fast systems (e.g TiC on SiC), several orders of Sezawa modes are observed together with the Rayleigh mode. The velocity dispersion of the modes has been obtained experimentally for both situations, allowing the elastic constants of the films to be determined. Effects of two deposition conditions, RF power and substrate bias, on the properties of the films are also considered. -
David Walliams Biography Example
David Walliams Introduction David Walliams (August 1971 – present) is a well-known celebrity who has appeared on many TV shows and now has branched out in to writing his own children’s books. How did this quiet boy from London become a household name? Read on to find out more. Point 1 Point Early life David Walliams was born in the London borough of Merton on the date of August 20th 1971. He grew up in Surrey. His full name is David Edward Williams. His mum’s name is Kathleen Williams, who was a lab technician at a school, and his dad’s – name is Peter Williams, who was a London transport engineer. Schooling Williams was educated at Collingswood Boy’s School in Wallington and Reigate Grammar School. Whilst he was at school, Point 2 Point he joined the Navy cadets just because he liked the uniform. He graduated with a Bachelor of Arts from the University of Bristol (1989-1992) where he spent three years. During the holidays, he worked at the National Youth Theatre where he – met his future comedy partner Matt Lucas. When Williams joined the National Youth Theatre, he changed his name to David Walliams as there was already another member of Equity, the actor’s union, going by his birth name. Point 3 Point and television and At the age of 24, David wrote for the Ant and Dec show from 1995 to 1997. He also performed in a Science fiction series – called Phantasmagoria in 1999 but mainly rose to fame in a series of BBC shows. -
Raman Spectroscopy and the Lattice Vibrations Cdcl2 and Cdbr2
SOLID STATE STUDIES: RAMAN SPECTROSCOPY AND THE L E ATTIC VIBRATIONS OF CdC12 AND CdBr2 A thesis presented for the degree of Doctor of Philosophy in Physics in the University of Canterbury, Christchurch, New Zealand. by D.J. Lockwood 1969 'rli::::.St6 1Q_C.., \ 7 (o . l-�17 To My Parents, God Bless Them. ii 1 B S T R A C T The fundamental lattice vibrations of the trigonal CdC1 structure (D 5 ) have been analyzed group theoret 2 3d ically, and symmetry coordinates have been constructed. The primitive cell has nine normal modes of vibration. All six optical modes are either infrared or Raman active, so a complete vibrational analysis is possible. esults of far-infrared measurements on a ourier-transform spectrometer together with Raman spectra recorded by argon laser excitation are presented for both CdC12 and CdBr2 • Symmetry assignments of the observed frequencies are made on the basis of the shift in frequency in going from chloride to bromide and the polarization behaviour. �eaks in the second-order axial infrared absorption spectra are assigned to allowed fundamental combinations. The lattice frequencies of CdC12 are consistent with those of the isomorphic crystals of CoC1 and MnC1 , which have also 2 2 been investigated by infrared absorption. An unsuccessful attempt was made to measure the electronic Raman spectra 2+ 2+ of Fe and Co ions in CdC12 and Cd.Br2 • The Raman spectra were measured on a Raman system comprising a 5 watt argon laser and a double monochromator, with photoelectric detection. The construction of the Raman spectrometer, and the associated signal processing electronics, is described in detail. -
Jackie Clune to Join Cast of Multi Award-Winning
A STAR STUDDED L E S M I S É R A B L E S OPENS NEXT DOOR AT THE GIELGUD THEATRE FOR 16 WEEKS ONLY CONTINUING THE SHOW’S RECORD-BREAKING RUN IN A SPECTACULAR AND INTIMATE STAGING OF THE LEGENDARY CONCERT MICHAEL BALL, ALFIE BOE, CARRIE HOPE FLETCHER, MATT LUCAS LEAD A CAST AND ORCHESTRA OF OVER 65 THE NEW PRODUCTION RE-OPENS THE NEWLY REFURBISHED QUEEN’S THEATRE IN DECEMBER 2019 Cameron Mackintosh today (6 February 2019) announces that for 16 weeks only Michael Ball (Javert), Alfie Boe (Jean Valjean), Carrie Hope Fletcher (Fantine) and Matt Lucas (Thénardier) will lead a large cast and orchestra of over sixty-five in the concert version of Les Misérables. Katy Secombe also joins to play Madame Thénardier and for three performances a week, the role of Jean Valjean will be played by John Owen-Jones. Further casting will be announced shortly. This spectacular staging of the legendary concert, previously seen in London at the Royal Albert Hall and the O2 Arena, will run from 10 August – 30 November 2019 at the intimate Gielgud Theatre next door to the current home of Les Misérables at the Queen’s Theatre. Public booking opens at 12noon (GMT) on Thursday 7 February 2019. Cameron Mackintosh said: “The success of Les Misérables continues to amaze me and break new ground. Despite the fact the show continues to play to 95% capacity we have been obliged to close the production at the Queen’s Theatre for 16 weeks this Autumn to do much needed work. -
In My Essay I Will Be Exploring the Reasons As to Why British Comedy Is Characterized the Way It Is
What are the British Actually Laughing At? An attempt to understand British comedy In my essay I will be exploring the reasons as to why British comedy is characterized the way it is. This will be done by taking into account the ways in which the British and American comedy industries contrast. I will evaluate the opposing commercial devices employed, the cultural differences, and the few similarities that these industries share. The British techniques, such as “sarcasm and irony”1 are vastly different to those used by the Americans who offer a more slapstick approach. This has resulted in both industries producing films and television programs that actually share little in common with each other, despite their popularity on both sides of the Atlantic. The British tend to approach situations with a mindset that comes across as significantly crude, cold and dismissive when juxtaposed with the classic American sunny disposition. I will explore this by comparing the UK and US versions of The Office. The general British national denial of emotions has moulded the route that comedy has taken, pushing comedy to become a way to stifle sentiment and a crutch for the population to lean on when feeling vulnerable. Yet interestingly, amongst both British and American audiences, an expectation appears concerning body image and weight, raising the question “are 2 comedians funnier when they are fat?”1F This has created a stereotype that links to the root of the need for comedy. The fact that both countries share this harsh stereotype lends something to the fact that all humans crave the desire to take pity upon or diminish the confidence of another through laughter, in order to feel better about oneself.