BARCELONA, SPAIN SCIENTIFIC COMMITTEE Pere Ginès (Chair), Jordi Bruix, Xavier Forns, Juan Carlos García-Pagan, Miquel Navasa
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SCIENTIFIC COMMITTEE Pere Ginès (Chair), Jordi Bruix, Xavier Forns, Juan Carlos García-Pagan, Miquel Navasa. Liver Unit, Hospital Clínic, Barcelona BARCELONA, SPAIN SCIENTIFIC COMMITTEE Pere Ginès (Chair), Jordi Bruix, Xavier Forns, Juan Carlos García-Pagan, Miquel Navasa. Liver Unit, Hospital Clínic, Barcelona BARCELONA, SPAIN Coordination: Oasis Events & Travel Solutions Graphic design: Jordi Sunyer Welcome! The members of the Scientific Committee welcome you to the medite- rranean city of Barcelona to celebrate the 13th Edition of the Internatio- nal Meeting on Therapy in Liver Diseases. This edition of the meeting coincides with the 50th Anniversary of the founding of the Liver Unit at Hospital Clinic and in recognition of this, we have introduced a new section to the meeting, ‘Barcelona-Clinic Grand Rounds’. As with the previous meetings, we are covering all the major areas of clinical hepatology which are moving and advancing rapidly in terms of new therapies, and are fortunate to count on world leaders in their fields to present these new advances. The Scientific Committee would like to thank the sponsors who have shown their continued support for this meeting. We look forward to welcoming all participants to the best clinical meeting on therapy in liver disease in the stunning location of Barcelona. Scientific Chair Pere Ginès Scientific Committee Jordi Bruix Xavier Forns Juan Carlos Garcia-Pagan Miquel Navasa ENDORSED BY: Fundació Clínic per a la Recerca Biomèdica. Barcelona Faculty Paolo Angeli Alejandro Forner University Hospital of Padova, Padova (Italy) Hospital Clínic of Barcelona, Barcelona (Spain) Quentin Anstee Xavier Forns Freeman Hospital, Newcastle upon Tyne (UK) Hospital Clínic of Barcelona, Barcelona (Spain) Jesús M. Bañales Scott Friedman Biodonostia Institute, San Sebastián (Spain) Icahn School of Medicine at Mount Sinai, New York (USA) Susanne Beckebaum Peter Galle University Hospital Münster, Münster (Germany) Mainz University Hospital, Mainz (Germany) Thomas Berg Martina Gambato University Hospital of Leipzig, Leipzig (Germany) University Hospital of Padova, Padova (Italy) Annika Bergquist Juan Carlos García-Pagán Karolinska Institutet, Huddinge (Sweden) Hospital Clínic of Barcelona, Barcelona (UK) Ulrich Beuers Andrea di Gottardi Amsterdam University Medical Center, Amsterdam, (Netherlands) University Hospital of Bern, Bern (Switzerland) Jordi Bruix Pere Ginès Hospital Clínic of Barcelona, Barcelona (Spain) Hospital Clínic of Barcelona, Barcelona (Spain) María Buti Isabel Graupera Hospital Vall d’Hebron, Barcelona (Spain) Hospital Clínic of Barcelona, Barcelona (Spain) Paolo Caraceni Virginia Hernández-Gea Hospital of Bologna, Bologna (Italy) Hospital Clínic of Barcelona, Barcelona (Spain) Laurent Castera Patrick S. Kamath Hospital Beaujon, Clichy (France) Mayo Clinic, Rochester (USA) Olivier Chazouillères Aleksander Krag Hôpital Saint Antoine, Paris (France) Odense University Hospital, Odense, (Denmark) Jordi Colmenero Frank Lammert Hospital Clínic of Barcelona, Barcelona (Spain) University of Homburg, Homburg (Germany) Gonzalo Crespo Sabela Lens Hospital Clínic of Barcelona, Barcelona (Spain) Hospital Clínic of Barcelona, Barcelona (Spain) John Dillon Ansgar Lohse University of Dundee, Dundee (Scotland, UK) University Medical Center Hamburg- Eppendorf, Hamburg (Germany) Javier Fernández Hospital Clínic of Barcelona, Barcelona (Spain) Faculty María C. Londoño Vlad Ratziu Hospital Clínic of Barcelona, Barcelona (Spain) University of Pierre and Marie Curie, Paris (France) Mala Maini María Reig University College of London, London (UK) Hospital Clínic of Barcelona, Barcelona (Spain) Josep Mallolas Mar Riveiro Hospital Clínic of Barcelona, Barcelona (Spain) Hospital Vall d’Hebron, Barcelona (Spain) Michael Manns Sergio Rodríguez University Hospital of Hannover, Hannover (Germany) Hospital Clínic of Barcelona, Barcelona (Spain) Zoe Mariño Didier Samuel Hospital Clínic of Barcelona, Barcelona (Spain) Hospital Paul Brousse, Villejuif (France) Ezequiel Mauro Alberto Sánchez-Fueyo Italian Hospital of Buenos Aires, Buenos Aires (Argentina) King’s College London, London, (UK) Christophe Moreno Arun Sanyal Hospital Erasme, Free University of Brussels, Brussels (Belgium) Virginia Commonwealth University, Richmond, (USA) Miquel Navasa Mohammed Siddiqui Hospital Clínic of Barcelona, Barcelona (Spain) Virginia Commonwealth University, Richmond, (USA) Philip Newsome Elsa Solà University of Birmingham, Birmingham (UK) Hospital Clínic of Barcelona, Barcelona (Spain) George V Papatheodoridis Cristina Solé Kapodistrian University of Athens Medical School, Athens (Greece) Hospital Clínic of Barcelona, Barcelon (Spain) Albert Parés Frank Tacke Hospital Clínic of Barcelona, Barcelona (Spain) University Hospital Aachen, Aachen (Germany) Antonello Pietrangelo Michael Trauner University Hospital of Modena, Modena (Italy) Medical University of Vienna, Vienna (Austria) Elisa Pose María Varela Hospital Clínic of Barcelona, Barcelona (Spain) University Hospital of Central Asturias, Oviedo (Spain) Bogdan Procopet Dominique Valla University of Medicine and Pharmacy, Iuliu Hatieganu Cluj-Napoca (Romania) Hospital Beaujon, Clichy (France) Pierre-Emmanuel Rautou Fabien Zoulim Hospital Beaujon, Clichy, (France) University Hospital College, Lyon (France) Wednesday 25 September 08.00 - 08.05 WELCOME and OPENING of MEETING 11.50 - 12.15 Modulation of inflammation in the transplanted liver? Pere Ginès (Barcelona) Alberto Sánchez-Fueyo (London) 17.30 - 18.30 JUAN RODÉS STATE of the ART LECTURE: Chair: Pere Ginès (Barcelona) 08.05 - 10.35 SYMPOSIUM AUTOIMMUNE LIVER DISEASES 12.15 - 13-45 SYMPOSIUM Chair: Albert Parés (Barcelona) The future of hepatology after hepatitis C OPPORTUNITIES AND CHALLENGES IN THE JOURNEY Michael Manns ( Hannover) 08.05 - 08.30 Diagnosis and treatment of autoimmune hepatitis TOWARDS HCV ELIMINATION IN SPAIN variant syndromes Chair: María Buti (Barcelona) 18.30 - 19.30 SYMPOSIUM María C. Londoño (Barcelona) Introduction LONG-TERM ALBUMIN ADMINISTRATION IN 08.30 - 08.55 Autoimmune hepatitis: management of patients María Buti (Barcelona) DECOMPENSATED CIRRHOSIS: CLINICAL CASES AND non responding to standard immunosuppression ANALYSIS OF THE RECENT CLINICAL TRIALS Ansgar Lohse (Hamburg) Challenges and opportunities for the current Chair: Rafael Bañares (Madrid) patient profile 08.55 - 09.20 Primary sclerosing cholangitis: more than an Zoe Mariño (Barcelona) 18:30h Welcome and introduction unique disease? Rafael Bañares (Madrid) Annika Bergquist (Huddinge) Challenges and opportunities for the future patient profile 18:35h Case report: long-term albumin administration 09.20 - 09.45 Advances in the treatment of primary sclerosing Marina Berenguer(Valencia) in refractory ascites cholangitis Marta Tonon (Padova) Michael Trauner (Vienna) The changing role of the hepatologist in this scenario Joaquín Cabezas (Santander) 18:45h Case report: The MACHT study 09.45 - 10.10 Novel therapies for primary biliary cholangitis Cristina Solé (Barcelona) Olivier Chazouillères (Paris) 13.45 - 15.00 LUNCH 18:55h Case report: The ANSWER study 10.10 - 10.35 The pruritus of cholestasis: pathogenesis 15.00 - 17.00 HOT TOPICS in HEPATOLOGY Manuel Tufoni (Bologna) and treatment Chair: Dominique Valla (Clichy) Ulrich Beuers (Amsterdam) 19:05h Description of the clinical studies, comparison among 15.00 - 15.30 Liver disease related to checkpoint inhibitors and them, and future perspectives 10.35 - 11.00 Coffee Break biotherapies Rafael Bañares (Madrid) Didier Samuel (Paris) 11.00 - 12.15 ADVANCES in LIVER TRANSPLANTATION 19:20h Q&A’s / Discussion Chair: Miquel Navasa (Barcelona) 15.30 - 16.00 Hot topics in alcoholic liver disease All Christophe Moreno (Brussels) 11.00 - 11.25 Management of patients at risk of cardiovascular 19:25h Conclusions and end of Symposium events in liver transplantation 16.00 - 16.30 Microvesicles as biomarkers in liver disease Rafael Bañares (Madrid) Gonzalo Crespo (Barcelona) Pierre-Emmanuel Rautou (Clichy) 11.25 - 11.50 Liver transplantation for alcoholic liver disease. 16.30 - 17.00 Hyperferritinemia and iron overload in metabolic What are the limits? syndrome Susanne Beckebaum (Münster) Antonello Pietrangelo (Modena) 17.00 - 17.30 Coffee Break 13th International Meeting On Therapy In Liver Diseases 13th International Meeting On Therapy In Liver Diseases 08.00 - 08.05 WELCOME and OPENING of MEETING 11.50 - 12.15 Modulation of inflammation in the transplanted liver? Pere Ginès (Barcelona) Alberto Sánchez-Fueyo (London) 17.30 - 18.30 JUAN RODÉS STATE of the ART LECTURE: Chair: Pere Ginès (Barcelona) 08.05 - 10.35 SYMPOSIUM AUTOIMMUNE LIVER DISEASES 12.15 - 13-45 SYMPOSIUM Chair: Albert Parés (Barcelona) The future of hepatology after hepatitis C OPPORTUNITIES AND CHALLENGES IN THE JOURNEY Michael Manns ( Hannover) 08.05 - 08.30 Diagnosis and treatment of autoimmune hepatitis TOWARDS HCV ELIMINATION IN SPAIN variant syndromes Chair: María Buti (Barcelona) 18.30 - 19.30 SYMPOSIUM María C. Londoño (Barcelona) Introduction LONG-TERM ALBUMIN ADMINISTRATION IN 08.30 - 08.55 Autoimmune hepatitis: management of patients María Buti (Barcelona) DECOMPENSATED CIRRHOSIS: CLINICAL CASES AND non responding to standard immunosuppression ANALYSIS OF THE RECENT CLINICAL TRIALS Ansgar Lohse (Hamburg) Challenges and opportunities for the current Chair: Rafael Bañares (Madrid) patient profile 08.55 - 09.20 Primary sclerosing cholangitis: more than an Zoe Mariño (Barcelona) 18:30h Welcome and introduction unique disease? Rafael Bañares (Madrid)