A Retrospective Cross Sectional Study on the Relation Between Nidana and Lakshana with Special Reference to Amavata a Thesis Submitted To
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A retrospective cross sectional study on the relation between nidana and lakshana with special reference to amavata A thesis submitted to The Late Vd. P.G. Nanal dept of Ayurveda Tilak Maharashtra Vidyapeeth, Pune For the Degree of Doctor of Philosophy (Ph.D.) In Samhita- Siddhanta subject Under the Board of Ph.D. Studies Submitted by Dr. Sri Nagesh K.A. Under the Guidance of Dr. Abhijit H.Joshi December 2016 C E R T I F I C A T E This is to certify that the thesis entitled “A retrospective cross sectional study on the relation between nidana and lakshana with special reference to amavata” which is being submitted herewith for the award of the Degree of Vidyavachaspati (Ph.D.) in Samhita siddhanta of Tilak Maharashtra Vidyapeeth, Pune is the result of original research work completed by Shri Dr.Sri Nagesh K.A. under my supervision and guidance. To the best of my knowledge and belief the work incorporated in this thesis has not formed the basis for the award of any Degree or similar title of this or any other University or examining body upon him. Dr. Abhijit H. Joshi Signature of the Research Guide Place: Pune Date: DECLARATION I hereby declare that the thesis entitled “A retrospective cross sectional study on the relation between nidana and lakshana with special reference to amavata” completed and written by me has not previously been formed as the basis for the award of any Degree or other similar title upon me of this or any other Vidyapeeth or examining body. [Dr. Sri Nagesh K.A.] Signature of the Research Student Place: Pune Date: iii ACKNOWLEDGEMENT I express my heartfelt and sincere gratitude to my beloved parents Smt. Susheela and Shree. N. Anantharamu, for supporting and inspiring me to go ahead with this work. I express my sincere thankfulness to my guide, Dr. Abhijit H.Joshi ji, Registrar and Head, Dept of Ayurveda, TMV, Pune, who supported during crisis and guided at every level with his immense knowledge and simplicity. I am thankful to my wife, Smt. Namrata rao K.S., whose immense love, care, support and suggestions have been materialistic in undertaking the study and completion of this work. I am sanctified by the blessings of His holiness Sri Sri Ravishankar ji, who provided all I needed. I am greatful to Dr. Deepak J. Tilak ji, Vice chancellor, Dr. S.P. Sardeshmukh ji, Dean of Tilak Maharashtra Vidyapeeth, Pune for providing me an opportunity to pursue my PhD. I express my gratitude to Dr. B.A.Venkatesh, Principal, SSCASR, Bengaluru for supporting me during the course of study. I express my gratitude to Dr.Sarbeswar kar, Academic dean, SSCASR, Bengaluru for providing me all the conveniences during the whole course of study. I would like to express my heartfelt gratitude to Dr. Rajesh Bhat, Assistant Professor, SDM Institute of Ayurveda and Hospital, Bengaluru who stood with me during difficult times and constantly inspired me for the completion of my work. I am obliged to Smt. Mahalakshmi, my mother-in-law, who checked my delay and inspired me to conclude my work at the earliest. I would like to express my sincere thankfulness to Dr. Sajitha. K., Vice-principal, SSCASR, Bengaluru for guiding me to undertake the study. i I would like to express my gratitude to my friends, Mr.Sreekar hegde, Dr. Nikhila B. hiremath, Dr.K.Savitha R. Shenoy, Dr.Ranjith kumar shetty, Dr.Sriharsha K.V., Dr. Varuni S.J., Dr. Naveen B.S., Dr. Soumyashree, Dr. Praveen kumar H., Dr. Santosha dixit, Dr. Jalindar dhamale and Dr. Arun sooraj for helping me in completing with observational study, data entry and contribution towards the subject. I would like to express my sincere gratitude to Dr. Keerthi Anil Keskar, Dr. Seethal Peenickal, Dr. Viroopakshayya L. Viraktamath, PG Scholars, Dept of PG studies in Samhita Siddhanta, SSCASR, Bengaluru for helping me for data entry and other works when it was most needed. I am thankful to Smt. Sushama pathak, Mr. Sachin, staff, Department of Ayurveda, Tilak Maharashtra Vidyapeeth, Pune for their endurance in responding to our doubts and clarifications. I am indebted to Medical superintendent, Chief administrative officer and MRD section of Sri Sri College of Ayurvedic Science and Research Hospital, Bengaluru for supporting for collection of data from patients. I would like to express my heartfelt thanks to Dr. Lancy D’Souza, Statistical and research consultant, Associate professor, University of Mysore for helping me in research work and statistical analysis by repeatedly guiding and checking the mistakes. I am obliged to Vidwan Shree Gangadhar Bhat, Maharaja Sanskrit College, Mysore for guiding me with inputs in the subject. I am appreciative to Mahamahopadhyaya Vidwan Shree Subraya sharma, Bengaluru for the positive inputs regarding the subject. I am indebted to all the patients who supported me by providing their valuable information for the study. I am thankful to all those who directly and indirectly helped me in the research work. -Dr. Sri Nagesh K.A. ii ABSTRACT Dosha being a primary factor for the disease expects complimentary circumstances for its manifestation. Nidana is a causative factor and it can be observed in different views. It can cause either being distant or nearer. Lakshana is an expression of the disease. Among karya karana sambandha, nidana means kaarana and karya being a disease proper itself. Lakshana is the indicator for the presence of the disease. Kaarana is multifaceted as every step in the manifestation of disease requires a causative factor. In amavata, right from the time of consumption of ahara, following the unsuitable vihara, movement of dosha from one location to another, selection of suitable location for the sthana samshraya and the development of lakshana expect reasons at every level. Viruddha ahara, viruddha vihara, mandagni, nishchalatva, vyayama after snigdha ahara are the reasons explained for amavata. Lakshanas being angamarda, aruchi, trishna, alasya, gaurava, jwara, apaka and anga shoonata. The study was to find the specificity of the nidana for the development of a specific lakshana. The nidana and its relation with lakshana will be critically analyzed literally as well as observed over the patients with classical amavata lakshana. Nidana will be identical with disease based on dravya, guna and karma following samya-vaishamya siddhanta. Disease should have the symptoms based on the samprapti thus; they have connectivity with the reason consumed. AIM: 1. To study the relation between nidana and lakshana with special reference to Amavata. OBJECTIVE: 1. To study the correlation between nidana and lakshana. iv MATERIALS AND METHODS: Materials: Literary study: References from various Ayurvedic classics, other ancient texts, reputed journals, articles and suitable websites will be collected and analyzed. Observational study: Diagnosed cases of Amavata of either sex will be collected for the study. A detailed proforma will be prepared considering different reasons pertaining to Amavata in Ayurvedic classics for the assessment. Methodology: The present study is a retrospective cross sectional study. Diagnosed cases of Amavata of either sex will be collected for the study between the age group of 30 to 60 years by a non randomized method. The causative factors in each case will be collected and compared with the symptom produced. RESULT ASSESSMENT: Result will be assessed based on the data obtained, analysis of the data based on the conceptual study and suitable statistical methods. DISCUSSION: Discussion will be based on the literary research made on the concepts, observations and the results obtained. CONCLUSION After discussion, outcome of the study will be concluded. Key words: Nidana, Lakshana, Amavata, Karya-kaarana, Roga, Ahara, Vihara, Dosha, Vata, Ama v CONTENT Sl. No Content Page number 1. Acknowledgement i 2. Declaration iii 3. Abstract iv 4. Key words v 5. Introduction 1-5 Review of Literature 6-61 Chapter 1: Nidana vivechana 6-19 6. Nirukti of nidana 8 7. Specialty of word ‘nidana’ 8 8. Types of nidana 9 9. Nidana paryaya 13 10. The basis for the different classification of 14 Nidana 11. Relation of Nidana with dosha and Dushya 14 12. Analysis on the synonyms 15 13. Characteristics of nidana 19 Chapter 2: Lakshana vivechana 20-27 14. Synonym of Lakshana 20 15. Critical analysis of synonyms 21 16. Hetutva for lakshana 22 17. Whether all the poorvaroopa continue as roopa? 22 18. What is the meaning of swaroopa? 23 19. Whether the vyadhi and roopa both one and the 24 same? 20. Are Aruchi etc lakshanas or vyadhi? 25 21. Lakshana bheda 25 Chapter 3: Karya Kaarana Siddhanta 28-51 22. Definition of Kaarana 28 23. Types of kaarana 28 24. Satkarya vada 29 25. Karya-kaarana siddhanta according to 34 contemporary literatures 26. Tarka 34 27. Ramanuja darshana- advaita 38 28. Nakulisha pashupata (Vaishnava) darshana 40 29. Sankhya darshana 40 30. Bauddha darshana 41 31. Naiyayika (nyaya) and Vaisheshika darshanas 41 32. Advaita- Vedanta darshana 42 33. Vyadhytpadaka pratibandhaka bhava 46 34. Nidana 46 35. Dosha 47 36. Dushya 48 37. Anubandha 49 Chapter 4: Review on Amavata 52-61 38. Nidana and Samprapti of Amavata 52 39. Symptoms of Amavata 53 40. Ama 53 41. Analysis of Amavata nidana 54 42. Characteristics and types of Viruddha 56 43. Ahetu 59 Chapter 5: Materials And Methods 62-67 44. Materials 62 45. Sources of data 63 46. Methodology 64 47. Aim and Objective 64 48. Research design 64 49. Method of collection of data 64 50. Inclusion and Exclusion criteria 65 51. Sample and Sampling method 65 52 Observations 66 53 Statistical analysis 66 Chapter 6: Observation 54. Observation 68-95 Chapter 7: Results 55. Results 96-107 Chapter 8: Discussion 108-135 56. Discussion on Nidana vivechana 108 57.