14Th International Congress

14th International Congress | 10-14 May The International Society for the Study of Fatty Acids & Lipids (ISSFAL) In collaboration with American Oil Chemists’ Society (AOCS)

PROGRAM (Subject to Change)

Monday, 10 May

08:00 - 08:45 (USA Eastern) 2021 Alexander Leaf Award 14:00 - 14:45 Paris 21:30 - 22:15 Adelaide Susan E. Carlson, PhD University of Kansas Medical Center | United States of America “Nutrition and DHA: Themes in My Life and Career ”

08:45– 10:05 (USA Eastern) 14:45 - 16:05 Paris Maternal & Infant Chair: Maria Makrides, SAHMRI, ISSFAL President | Australia 22:15 - 23:20 Adelaide Co-Chair: Yan Quin, BASF | Singapore 08:50 / 14:50 / 22:20 09:05 / 15:05 / 22:35 09:20 / 15:20 / 22:50 09:35 / 15:35 / 23:05 09:50 / 15:50 / 23:20 Prenatal Omega-3 supple- Long-chain polyunsaturated Human milk fatty acid com- Maternal Red Blood Cell Diet-induced fat accumula- mentation for the preven- fatty acids and lipid peroxi- position and maternal life- Long-chain Fatty Acid Sta- tion during adulthood is not tion of preterm birth - a dation products in donor style-related time trends: a tus Is Associated with a affected by early-life expo- double edged sword? human milk in the U.K.: comparison between the sure to infant formula with Results from the LIMIT two- two Ulm Birth Cohort Stud- Higher Risk of Premature added MFGM as a source centre cross sectional study ies. Birth in Urban South Africa: of phospholipids The Nuped Study Karen Best Simon Dyall Linda Siziba Elizabeth Symington Bert van de Heijning SAHMRI, Univ. of Adelaide University of Roehampton University Medicine ‐ Leipzig UNISA Danone Nutricia Research Australia United Kingdom Germany South Africa Netherlands All topical sessions will have 10 Minutes of Oral Presentation and 5 Minutes Q&A. There will be an additional 20 Minutes of Panel Q&A after the last presenter.

13:00 - 13:45 (USA Eastern) Very Long Chain PUFA in Macular Degeneration: 19:00 - 19:45 Paris Learning from the Young to Treat the Old 02:30 - 03:15 Adelaide (Tuesday) Prof. Martin-Paul Agbaga University of Oklahoma | United States of America 13:45 - 15:05 (USA Eastern) Eicosanoids & Lipid Mediators 19:45 - 21:05 Paris Chair: Saame ‘Raz’ Shaikh, Univ. of North Carolina |USA 03:15 - 04:20 Adelaide (Tuesday) Co-Chair: Abe Kasonga, Univ. of Pretoria | South Africa

13:50 / 19:50 / 03:20 14:05 / 15:05 / 03:35 14:20 / 15:20 / 03:50 14:35 / 15:35 / 04:05 14:50 / 15:50 / 04:20

Lipid mediator response New dose strategy for 4-F4-neuroprostane and Resolvin E1 has Oxidized lipids mediators may be modulated by omega-3 fatty acids using its potent biological action therapeutic potential for within surgical incisions in recreational running body surface area and a in cardiovascular improving glucose humans – a clinical study. independently of anti- novel omega-3 index, the diseases. homeostasis in a host- oxidative stress adaption EDD-index. genome dependent manner Linda Malan Linda Ljungblad Jean-Marie Galano Saame ‘Raz’ Shaikh Anthony Domenichiello North-West University Karolinksa Institute CNRS Univ. of North Carolina Nat’l. Institute on Aging South Africa Sweden France USA USA

For more information: www.issfalcongress.com PROGRAM (Subject to Change)

14th International Congress | 10-14 May The International Society for the Study of Fatty Acids & Lipids (ISSFAL) In collaboration with American Oil Chemists’ Society (AOCS)

Tuesday, 11 May

06:00 - 06:45 (USA Eastern) SFEL: La Médaille Chevreul 12:00 - 12:45 Paris 19:30 - 20:15 Adelaide Prof. Robert Gibson SAHMRI | Australia “Old and new adventures with fatty acids and their oxylipins: The road towards personalised clinical nutrition.”

06:45– 08:20 (USA Eastern) 12:45 - 14:20 Paris SFEL Sessions 20:15 - 21:50 Adelaide Chairs: Phillipe Guesnet & Claire Bourlieu-Lacanal INRAE | France

06:50 / 12:50 / 20:20 07:10 / 13:10 / 20:40 07:30 / 13:30 / 21:00 An overview of milk polar lipids physico- Milk sphingolipids: towards joint effects on lipid Impact of dairy components addition on meta- chemical attributes and nutritional interest metabolism, intestinal health and gut microbiota bolic and microbiota programming: where do we stand? Claire Bourlieu-Lacanal Marie-Caroline Michalski Marion Lamaire INRAE INRAE INRAE France France France

10:00 - 10:45 (USA Eastern) Nutrition and Saturated Fats 16:00 - 16:45 Paris 23:30 - 00:15 Adelaide Prof. Arne Astrup Novo Nordisk Foundation & Univ. of Copenhagen | Denmark

10:45– 12:05 (USA Eastern) 16:45 - 18:05 Paris Cardiovascular Chair: Robert Block, Univ. of Rochester | USA 00:15 - 01:35 Adelaide Co-Chair: Logesh Rajan, JSS College of Pharmacy | India 10:50 / 16:50 / 00:20 11:05 / 17:05 / 00:35 11:20 / 17:20 / 00:50 11:35 / 15:35 / 23:05 11:50 / 15:50 / 23:20

Circulating omega-3 fatty Omega-3 Fatty Acid Role of Eicosapentanae- Omega-3 fatty acids Omega-3 Fatty Acids acid levels and total and Levels and Left noic acid (EPA) in Heart reduce oxidative stress and Aspirin Interact in cause-specific mortality: Ventricular Diastolic failure Prediction: The in cultured, lipopolysac- Primary Cardiovascular prospective evidence Function in Patients with Multi-Ethnic Study of charide-stimulated mac- Disease Prevention from 17 cohorts in the Heart Failure with Atherosclerosis rophages from patients Fatty Acids and Preserved Ejection with abdominal aortic Outcomes Research Fraction: a Substudy aneurysm Consortium from the Aldo-DHF Randomized Controlled Trial William Harris Clemens von Schacky Venugopal Mudgundi Fraser Russell Robert Block Fatty Acid Research Inst. Univ. of Munich Univ. of Rochester Univ. of the Sunshine Coast Univ. of Rochester USA Germany USA Australia USA PROGRAM (Subject to Change)

14th International Congress | 10-14 May The International Society for the Study of Fatty Acids & Lipids (ISSFAL) In collaboration with American Oil Chemists’ Society (AOCS)

Wednesday, 12 May

08:00 - 08:45 (USA Eastern) Long Chain n-3 Fatty Acids in Pregnancy: 14:00 - 14:45 Paris 21:30 - 22:15 Adelaide Potential for Prevention of Pre-Term Birth Prof. Sjurdur Olsen Statens Serum Institut | Denmark

08:45 - 10:05 (USA Eastern) 14:45 - 16:05 Paris Nutrition Chair: Jeannine Baumgartner, ETH | Switzerland 22:15 - 23:35 Adelaide Co-Chair: To be announced

08:50 / 14:50 / 22:20 09:05 / 15:05 / 22:35 09:20 / 15:20 / 22:50 09:35 / 15:35 / 23:05 09:50 / 15:50 / 23:20

The Structure-Activity Assessing the effect of Conversion of dietary Krill oil reduced osteoar- Additional oral Relationship of Dietary omega-3 docosapentae- polyunsaturated fats thritic knee pain in adults presentation TBD. EPA in Nutritional and noic (DPA) on inflamma- between humans and with mild to moderate Health Benefits tion, using the Caco-2 gut rodents: A review of knee osteoarthritis: A 6- epithelium model month multicentre, ran- allometric scaling models domized double-blind,

placebo-controlled trial Tiantian Zhang Luke Durkin Jay Whelan Welma Stonehouse Ocean University of China Univ. of Southampton Univ. of Tennessee CSIRO China United Kingdom United States Australia

13:00 - 13:45 (USA Eastern) 2021 Early Career Award 19:00 - 19:45 Paris 02:30 - 03:15 Adelaide (Thursday) Prof. Ameer Taha University of California, Davis | USA “Metabolism, turnover and the role of oxidized linoleic acid metabolites in brain”

13:45– 15:05 (USA Eastern) 19:45 - 21:05 Paris Obesity & Diabetes Chairs: Ken Stark, Univ. of Waterloo | Canada 03:15 - 04:20 Adelaide (Thursday) Co-chair: Xinyan Bi, Singapore Inst. of Food and Biotechnology Innovation | Singapore

13:50 / 19:50 / 03:20 14:05 / 20:05 / 03:35 14:20 / 20:20 / 03:50 14:35 / 20:35 / 04:05 14:50 / 20:50 / 04:20

Docosahexaenoic acid plus Baseline omega-3 status CLA isomers prevents Erythrocyte n-6 polyun- Plasma phospholipid fatty is associated with nerve weight gain but exacer- hydroxytyrosol supplemen- saturated fatty acids, gut acid patterns are associ- regeneration following 1- bates dysplipidemia tation prevents metabolic microbiota and incident ated with adiposity and year of omega-3 nutrition posed by Western diet in disturbance in white adi- type 2 diabetes: a pro- the metabolic syndrome therapy in patients with ApoE null Mice with co- pose tissue in mice fed a spective cohort study in black South Africans: a diabetic neuropathy administration of conven- high-fat diet through PPAR- cross-sectional study tional PPAR agonist. γ and Nrf2 up-regulation and SREBP-1c and NF-kB down-regulation Evan Lewis Suresh Mohankumar Rodrigo Valenzuela Zelei Miao Alice Ojwang Univ. of Toronto JSS College of Pharmacy Univ. of Toronto Westlake University Technical Univ. of Kenya Canada India Canada China Kenya

For more information: www.issfalcongress.com PROGRAM (Subject to Change)

14th International Congress | 10-14 May The International Society for the Study of Fatty Acids & Lipids (ISSFAL) In collaboration with American Oil Chemists’ Society (AOCS)

17:00 - 19:35 (USA Eastern) 23:00 - 01:35 Paris AOCS/ISSFAL Joint Session on Nutrition Chair: RJ Scott Lacombe, Univ. of Texas | USA 06:30 - 09:05 Adelaide (Thursday) Co-chair: Martha Belury “Clinical and pre-clinical studies of polyunsaturated fatty acids” 17:10 / 23:00 / 06:40 17:35 / 23:35 / 07:05 18:00 / 00:00 / 07:30 18:25 / 00:35 / 07:55 18:50 / 00:50 / 08:20 19:15 / 01:15 / 08:45

High-oleic Ready-to- Associations of n-3 Effect of n-3 Long- Modulation in Dietary Elucidating the Effects Dietary Alpha-linolenic use Therapeutic Food Fatty Acid Status Dur- chain Polyunsaturated Linoleic Acid Intake of Dihomo-γ-linolenic Acid Is Necessary for with or Without Do- ing Early Pregnancy Fatty Acids on Cogni- Results in Differential Acid (DGLA) and the the Increase in Eicosa- cosahexaenoic Acid with Perinatal Depres- tion in Adults with Transcriptomic Re- Dgla-rich Green Micro- pentaenoic Acid Fol- Supports Normal sion at 12 Months Autism Spectrum Dis- sponse to Ethanol alga in a Zebrafish lowing Docosahex- Growth and Recovery Postpartum in Urban order: A Randomized Binge Model of Gut Inflam- aenoic Acid Intake in Malnourished Mala- South Africa: The Crossover Trial mation wian Children: A Ran- Nuped Study domized Controlled Trial RJ Scott Lacombe Ester Osuna Lotte Lauritzen Check Chen Ekaterina Novichkova Adam Metherel Univ. of Texas ETH Univ. of Copehagen NIAAA Ben Gurion University Univ. of Toronto USA Switzerland Denmark USA Israel Canada

Thursday, 13 May

10:00 - 10:45 (USA Eastern) Cataloging EPA and DHA Science: 16:00 - 16:45 Paris 23:30 - 00:15 Adelaide Introducing GOED’s Clinical Studies Database Aldo Bernasconi, VP of Data Science, GOED | USA Moderator: Ellen Schutt, Executive Director, GOED | USA

10:45 - 12:05 (USA Eastern) 16:45 - 18:05 Paris Lipid Metabolism Chair: Richard Bazinet, Univ. of Toronto, ISSFAL Imm’d. Past President | Canada 00:15 - 02:35 Adelaide (Friday) Co-chair: Zhen Wang, Wilmar International | China

08:45 / 14:45 / 22:15 09:00 / 15:00 / 22:30 09:15 / 15:15 / 22:45 09:30 / 15:30 / 23:00 09:45 / 15:45 / 23:15

Acute injection of DHA Plasma unesterified Acyl-CoA synthetase 6 is FADS2 Function Loss at Accretion and triglyceride emulsions eicosapentaenoic acid is required for brain the Major Cancer Pharmacokinetics of Di- after hypoxic-ischemic converted to docosahexaenoic acid Hotspot 11q13 Locus Deuterated Linoleic Acid brain injury in mice docosahexaenoic acid retention and Alters Fatty Acid in Human Patients with a increases EPA and EPA- (DHA) in the liver and neuroprotection during Metabolism Neurodegenerative derived pro-resolving supplies the brain with aging Disease mediators in brain and DHA in the presence or blood absence of dietary DHA

Denny Kollareth Adam Metherel Jessica Ellis Kumar Kothapalli Genevieve James Columbia University Univ. of Toronto East Carolina University Univ. of Texas Univ. of Texas USA Canada USA USA USA

EAST: 01:00 GMT (13 May) Meet the Professors (Two Sessions) WEST: 17:00 GMT (13 May) Eastern & Western Hemisphere Details regarding the “Meet the Professors” sessions will be announced. ALL POSTER PRESENTATIONS WILL BE AVAILABLE ONLINE FROM 15 APRIL THROUGH 14 MAY For more information: www.issfalcongress.com PROGRAM (Subject to Change)

14th International Congress | 10-14 May The International Society for the Study of Fatty Acids & Lipids (ISSFAL) In collaboration with American Oil Chemists’ Society (AOCS) Friday, 14 May

06:00 - 06:45 (USA Eastern) N-3 Polyunsaturated Fats & The Resolu- 12:00 - 12:45 Paris 19:30 - 20:15 Adelaide tion of Neuroinflammation Prof. Sophie Laye National Institute of Agricultural Research (INRA) |France 06:45– 08:05 (USA Eastern) Neuroscience 12:45 - 14:05 Paris Chairs: Adina Michael-Titus, Univ. of London | United Kingdom 20:15 - 21:35 Adelaide Co-chair: Julia Kelliher, Penn State University | USA

06:50 / 12:50 / 20:20 07:05 / 13:05 / 22:35 07:20 / 13:20 / 20:50 07:35 / 13:35 / 21:05 07:50 / 13:50 / 21:20 Supplementation with oil Effect of omega-3 A combined n-3 fatty A new perspective on Ketones from MCT im- rich in eicosapentaenoic LCPUFA acid and flavan-3-ol roles of polyunsaturated prove processing speed acid, but not in docosahex- supplementation on supplement does not fatty acids and in MCI as a function of aenoic acid, improves glob- cognition in children and improve cognition or carotenoids in exudative improved white matter al cognitive function in energetics. adolescents: an brain structure in older age-related macular healthy, young adults: A expanded systematic age: The Cognitive degeneration randomised controlled trial literature review with Ageing, Nutrition and focus on DHA/EPA dose Neurogenesis (CANN) and omega-3 index. trial

Inge van der Wurff Philippa Jackson Anne Marie Minihane Jetty Chung-Yung Lee Stephen Cunnane Open University Northumbria University Univ. of East Anglia Univ. of Hong Kong University of Sherbrooke Netherlands United Kingdom United Kingdom Hong Kong SAR Canada

11:00– 11:45 (USA Eastern) Application of Lipidomics to the 17:00 - 17:45 Paris 00:30 - 01:15 Adelaide (Saturday) Identification of Bioactive Lipid Mediators Prof. Valerie O’Donnnell Cardiff University | Wales 11:45 - 13:05 (USA Eastern) 17:45 - 19:05 Paris Lipidomics Chairs: Anna Nicolaou, Univ. of Manchester | United Kingdom 01:15 - 02:35 Adelaide (Saturday) Co-Chair: Klaudia Steckel, Univ. of Waterloo | Canada

11:50 / 17:50 / 01:20 12:05 / 17:05 / 01:35 12:20 / 17:20 / 01:50 12:35 / 17:35 / 02:05 12:50 / 17:50 / 02:20 Challenges in the Solvent-mediated (SM) Determining the A Cross-talk betwen Lipid particles as development of dried spot covalent adduct absorption and tissue lipidomics and MRI interfacial reservoirs of methods for separating chemical ionization incorporation kinetics of hepatic fat fraction antioxidants in Pickering and measuring the level (CACI-)MS/MS for linoleic acid-derived 13- investigating the effect of emulsions of free fatty acids in identification of fatty acid hydroxyoctadecadienoic high concentrate Omega breast milk methyl esters with acid in rats -3 in Non-alcoholic fatty unusual double bond liver disease positions on a Shimadzu triple quadrupole mass spectrometer

Chang Gao Donghao Wang Zhichao Zhang Rachel Yu Claire Berton-Carabin SAHMRI Cornell University Univ. of California, Davis BASF Wageningen University Australia USA USA China Netherlands

13:00– 13:45 (USA Eastern) 19:00 - 19:45 Paris Closing Session & ISSFAL 2022 Prof. Richard Bazinet, ISSFAL Immediate Past President 02:30 - 03:15 Adelaide (Saturday) Bernadette Delplanque, ISSFAL 2022 Congress Chair 9-13 July 2022