Schatzkis Ring. an Unusual Clinical and Radiological Presentation

Total Page:16

File Type:pdf, Size:1020Kb

Schatzkis Ring. an Unusual Clinical and Radiological Presentation Case Reports Sameer Pusalkar, MD, Tarek E. Abdellatif, MD. ABSTRACT Schatzki’s ring is a lower esophageal mucosal ring associated with a small sliding hiatus hernia. Most investigators described it as either an asymptomatic or symptomatic entity with chronic recurrent presentation of dysphagia. Barium swallow study in patients with Schatzki’s ring was described as a thin smooth circumferential constriction at the GE junction. This case report describes an unusual clinical and radiological presentation in a patient with Schatzki’s ring. Our adult male patient experienced sudden dysphagia, followed by spontaneous relief after an interval of 12 hours without specific treatment. Radiological findings were highly suggestive of lower esophageal malignancy. However, this possibility could be excluded by upper endoscopy and histopathological examination of biopsies taken from the lesion. The condition was diagnosed as Schatzki’s ring with unusual clinical and radiological presentation. Saudi Med J 2005; Vol. 26 (3): 467-469 chatzki’s ring is a lower esophageal mucosal Case Report. A 58-year-old, American male S ring associated with a small sliding hiatus presented with sudden and complete dysphagia, hernia.1,2 Most investigators described it as either which was followed by spontaneous relief after an asymptomatic or symptomatic entity with chronic interval of 12 hours. This was a single episodic and recurrent presentation of dysphagia.3 The presentation by the patient. Dysphagia did not incidence of symptomatic Schatzki’s ring is follow a particular type of solid food intake such as reported to be approximately 0.5% in patients meat. Also, patient did not have any associated undergoing routine upper gastrointestinal (GI) abdominal, thoracic or constitutional symptoms. barium examination.4 In barium swallow study, Clinical examination of the patient was Schatzki’s ring is described as a thin smooth unremarkable. Barium swallow was carried out circumferential constriction at the gastroesophageal shortly after presentation and this showed complete (GE) junction. We are reporting a case of Schatzki’s obstruction at the lower end of esophagus with an ring presented with unusual clinical and radiological irregular filling defect and shouldering sign manifestations that closely mimicked lower (Figures 1 & 2). These findings were highly esophageal carcinoma. This case report pays suggestive of lower esophageal malignancy. The attention to the importance of full investigations and patient was admitted, received no specific treatment close follow up of patients with Schatzki’s ring to but was put under observation and was given exclude the possibility of esophageal malignancy. intravenous fluids and nothing by mouth. Twelve From the Department of Radiology (Pusalkar) and Department of General Surgery (Abdellatif), Ghassan Najeeb Pharaon Hospital, Khamis Mushayt, Kingdom of Saudi Arabia. Received 30th August 2004. Accepted for publication in final form 4th December 2004. Address correspondence and reprint request to: Dr. Tarek E. Abdellatif, Consultant Surgeon and Laparoscopist, GNP-Hospital, PO 761, Khamis Mushayt, Kingdom of Saudi Arabia. Tel. +966 (7) 2200002 Ext. 604. E-mail: [email protected] 467 Schatzki’s ring … Pusalkar & Abdellatif hours following admission, the patient experienced spontaneous and complete relief of dysphagia. Follow-up radiological exposure was taken after relief of dysphagia revealed free passage of barium through the esophagogastric junction into the stomach. The next day of hospitalization, an esophagogastroscopy was performed which did not show any evidence of tumor mass, instead, it showed a constricting ring at the lower end of oesophagus accompanied by a sliding hiatus hernia, and a tiny ulcer over the crater of the ring (Figure 3); signs suggestive of gastro-esophageal reflux disease (GORD). Biopsies taken from the lesion site for histopathological examination revealed no signs of malignancy. The case was diagnosed as Schatzki’s ring of lower end of esophagus. The patient was Figure 1 - Barium swallow showing complete arrest of the dye at the discharged on the second day of admission free and esophagogastric junction and irregular filling defect. was given omeprazole for treatment of GORD and lower esophageal ulcer. Follow up of the patient for about one year did not report any recurrence of the symptoms or abnormal radiological or endoscopic findings. Discussion. Schatzki’s ring was first described in literature by Schatzki and Gary in 1953.5 The exact pathogenesis of these rings is unknown. Most investigators believe that Schatzki’s ring is an annular ring-like stricture caused by scarring as a result of reflux esophagitis.4,6 The luminal diameter of mucosal ring is the primary factor that determines the presence or absence of dysphagia.7 In 1963, Schatzki reported that if the luminal diameter of ring is less than 13 mm, patients regularly experience intermittent dysphagia to solid food.8 Some patients may present with acute food impaction causing an obstruction. It occurs that a large piece of meat becomes stuck at the level of Figure 2 - Barium swallow showing shouldering sign at the ring, hence the term steakhouse syndrome. On the esophagogastric junction which mimics carcinoma of the lower esophagus. other hand, the clinical course of Schatzki’s ring shows that if the patient passes or regurgitates the food bolus the symptoms resolve. Perforation of esophagus is an extremely rare, but important complication of Schatzki’s ring and occurs after meat impaction with only one such case reported until date.9 There is no age bar for the development of Schatzki’s ring and it can also present in children.10 In our case, patient did not give history of specific type of solid food intake shortly before development of dysphagia. Also, he had a complete relief of dysphagia without regurgitation of food. Thus, the patient did not receive any of specific treatment for Schatzki’s ring but only for the associated GE reflux and the tiny ulcer at lower end of the esophagus. Barium swallow study in patients with Schatzki’s ring at the time of dysphagia is Figure 3 - Esophagogastroscopy showing constricting ring at the expecting to show a thin smooth circumferential esophagogastric ring with a tiny ulcer over its crater. constriction at the GE junction.5 In our case we 468 Saudi Med J 2005; Vol. 26 (3) www.smj.org.sa Schatzki’s ring … Pusalkar & Abdellatif describe a rare radiological presentation of episodic References Schatzki’s ring in which barium swallow findings 1. Chapman AH. The salivary glands, pharynx and esophagus. closely mimicked lower esophageal malignancy In: Sutton D, editor. Textbook of radiology and imaging. regarding the presence of irregular filling defect and New York, Edinburgh, London, Madrid: Churchill shouldering sign. However, endoscopy and Livingston; 1998. p. 803-804. histopathological examination of tissues taken from 2. Hendrix TR. Schatzki ring, epithelial junction and hiatus hernia: An unresolved controversy. Gastroenterology 1980; the site of lesion excluded malignancy. There is no 79: 584-585. reported evidence of association of Schatzki’s ring 3. Zaveri JP, Nathani RR, Shah RL. Schatzki’s ring: An and esophageal malignancy.7 Generally, treatment obscure cause of dysphagia (case report). J Post Grad Med 1987; 33: 99-101. of Schatzki’s ring is offered only in the 4. Johnson AC, Lester PD, Johnson S, Sudarsanam D, Dunn symptomatic group of patients and the choices of D. Oesophagogastric ring: why and when we see it, and treatment include dilatation and rupture of ring or what it implies: a radiologic-pathologic correlation. South Med J 1992; 85: 946-952. excision of ring with repair of hiatus hernia. The 5. Schatzki R, Gary JE. Dysphagia due to diaphragm-like recurrence rate of symptoms is considerably high localized narrowing in the lower esophagus (lower after dilatation. On the other hand, surgical option is esophageal ring). Am J Roentgenol 1953; 70: 911-922. 6. Bugden WF, Delmonico JE Jr. Lower esophageal Web. J reserved only for patients with reflux as Thorac Surg 1956; 31: 1-18. predominant complaint rather than dysphagia with 7. Marshall JB, Kretschmar JM, Diaz-Arias AA. the realization that there will be a sizable failure Gastroesophageal reflux as a pathogenic factor in the rate. Radiological and endoscopic follow up of our development of symptomatic lower esophageal rings. Arch Inter Med 1990; 150: 1669-1672. patient for one year did not show recurrence of 8. Schatzki R. The lower esophageal ring: Long-term follow symptoms and even the ulcer in the lower up of symptomatic and asymptomatic rings. Am J esophagus healed completely. Roentgenol Radium Ther Nucl Med 1963; 90: 805-810. 9. Buckley K, Buonomo C, Husain K, Nurko S. Schatzki ring in children and young adults: clinical and radiological Acknowledgment. The authors would like to thank Mrs. findings. Pediatr Radiol 1998; 28: 884-886. Andrea Fernandez and Mrs. Nelia Enriquez from the 10. Miller S. Hines C Jr, Ochsner JL. Spontaneous perforation department of imaging for their assistance in preparing this of the esophagus associated with a lower esophageal ring. manuscript. Am J Gastroenterol 1988; 83: 1405-1408. www.smj.org.sa Saudi Med J 2005; Vol. 26 (3) 469.
Recommended publications
  • Annular Pancreas Causing Gastric Outlet Obstruction in Adult: a Case Study
    IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 15, Issue 4 Ver. IX (Apr. 2016), PP 05-06 www.iosrjournals.org Annular Pancreas Causing Gastric Outlet Obstruction in Adult: A Case Study Dr Shyam Charan Baskey1, Dr Ramchandra Besra1,Dr Niranjan Mardi1, 2 2 Dr Shital Malua , Dr Pankaj Bodra 1Senior Resident,1Ex Senior Resident, 1Junior Resident1, 2Associate Professor Department of Surgery, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand India, Pin- 834009 Abstract: Annular pancreas is one of rare congenital anomalies that rarely manifest in adult. We hereby discuss our experiences with one of the presentation of annular pancreas. A 20 years male presented with pain abdomen symptom of gastric outlet obstruction, radiological investigation reported as chronic pancreatitis, on high level of suspicion exploratory laprotomy done with finding of annular pancreas. Bypass surgery done. Patients discharged uneventful. Key words: Annular pancreas, gastric outlet obstruction, CT scan, exploratory laprotomy. I. Introduction Annular pancreas is a congenital anomaly that consists of a ring of pancreatic tissue partially or completely obstructing second part of duodenum. It is formed due to failure of the ventral bud to rotate. Thus, it elongates and encircles the upper part of the duodenum, it can present in a wide range of clinical severities and can affect neonates to the elderly like peptic ulcer, pancreatitis, obstructive jaundice, gastric outlet obstruction etc, thereby making the diagnosis difficult, although diagnosis of annular pancreas can be made preoperatively by upper gastrointestinal endoscopy, CT scan, Endoscopic retrograde cholangiopancreatography (ERCP) and Magnetic resonance cholangiopancratography (MRCP).
    [Show full text]
  • Dysphagia What Is Dysphagia? Dysphagia Is a General Term Used to Describe Difficulty Swallowing
    Dysphagia What is Dysphagia? Dysphagia is a general term used to describe difficulty swallowing. While swallowing may seem very involuntary and basic, it’s actually a rather complex process involving many different muscles and nerves. Swallowing happens in 3 different phases: Insert Shutterstock ID: 119134822 1. During the first phase or oral phase the tongue moves food around in your mouth. Chewing breaks food down into smaller pieces, and saliva moistens food particles and starts to chemically break down our food. 2. During the pharyngeal phase your tongue pushes solids and liquids to the back of your mouth. This triggers a swallowing reflex that passes food through your throat (or pharynx). Your pharynx is the part of your throat behind your mouth and nasal cavity, it’s above your esophagus and larynx (or voice box). During this reflex, your larynx closes off so that food doesn’t get into your airways and lungs. 3. During the esophageal phase solids and liquids enter the esophagus, the muscular tube that carries food to your stomach via a series of wave-like muscular contractions called peristalsis. Insert Shutterstock ID: 1151090882 When the muscles and nerves that control swallowing don’t function properly or something is blocking your throat or esophagus, difficulty swallowing can occur. There are varying degrees of Dysphagia and not everyone will describe the same symptoms. Your symptoms will depend on your specific condition. Some people will experience difficulty swallowing only solids, or only dry solids like breads, while others will have problems swallowing both solids and liquids. Still others won’t be able to swallow anything at all.
    [Show full text]
  • The Gastrointestinal Tract Frank A
    91731_ch13 12/8/06 8:55 PM Page 549 13 The Gastrointestinal Tract Frank A. Mitros Emanuel Rubin THE ESOPHAGUS Bezoars Anatomy THE SMALL INTESTINE Congenital Disorders Anatomy Tracheoesophageal Fistula Congenital Disorders Rings and Webs Atresia and Stenosis Esophageal Diverticula Duplications (Enteric Cysts) Motor Disorders Meckel Diverticulum Achalasia Malrotation Scleroderma Meconium Ileus Hiatal Hernia Infections of the Small Intestine Esophagitis Bacterial Diarrhea Reflux Esophagitis Viral Gastroenteritis Barrett Esophagus Intestinal Tuberculosis Eosinophilic Esophagitis Intestinal Fungi Infective Esophagitis Parasites Chemical Esophagitis Vascular Diseases of the Small Intestine Esophagitis of Systemic Illness Acute Intestinal Ischemia Iatrogenic Cancer of Esophagitis Chronic Intestinal Ischemia Esophageal Varices Malabsorption Lacerations and Perforations Luminal-Phase Malabsorption Neoplasms of the Esophagus Intestinal-Phase Malabsorption Benign tumors Laboratory Evaluation Carcinoma Lactase Deficiency Adenocarcinoma Celiac Disease THE STOMACH Whipple Disease Anatomy AbetalipoproteinemiaHypogammaglobulinemia Congenital Disorders Congenital Lymphangiectasia Pyloric Stenosis Tropical Sprue Diaphragmatic Hernia Radiation Enteritis Rare Abnormalities Mechanical Obstruction Gastritis Neoplasms Acute Hemorrhagic Gastritis Benign Tumors Chronic Gastritis Malignant Tumors MénétrierDisease Pneumatosis Cystoides Intestinalis Peptic Ulcer Disease THE LARGE INTESTINE Benign Neoplasms Anatomy Stromal Tumors Congenital Disorders Epithelial Polyps
    [Show full text]
  • Identifying the LINX® Reflux Management System Patient
    Identifying the LINX® Reflux Management System Patient Gastroesophageal Reflux Disease, or GERD is a chronic What is GERD? digestive disease, caused by weakness or inappropriate relaxation in a muscle called the lower esophageal sphincter (LES). Normally, the LES behaves like a one-way valve, allowing food and liquid to pass through to the stomach, but preventing stomach contents from flowing back Symptoms of GERD into the esophagus. • Heartburn • Chest pain • Regurgitation • Dysphagia (difficulty swallowing) • Dental erosion and bad breath • Cough • Hoarseness • Sore throat • Asthma Complications * GERD can lead to potentially serious complications including: • Esophagitis (inflammation, irritation or swelling of the esophagus) • Stricture (narrowing of the esophagus) • Barrett’s esophagus (precancerous changes to the esophagus) • Esophageal cancer (in rare cases)** Diagnosing GERD • Response to medication • Endoscopy/EGD • Bravo pH monitoring *LINX is not intended to cure, treat, prevent, mitigate or diagnose these symptoms or complications **0.5% of Barrett’s esophagus patients per year are diagnosed with esophageal cancer ® Who is the LINX Reflux Management System patient? • Diagnosed with GERD as defined by abnormal pH testing • Patients seeking an alternative to continuous acid supression therapy LINX Reflux Management System patient workup • Objective reflux – pH testing • Anatomy – EGD • Esophageal function – Manometry Restore don’t reconstruct1* • Requires no alteration to stomach anatomy • Preserved ability to belch and vomit2† • Removable • Preserves future treatment options1‡ Patient benefits at 5 years1 • 85% of patients were off daily reflux medications after treatment with LINX Reflux Management System§ • Elimination of regurgitation in 99% of patients¶ • 88% elimination of bothersome heartburn** • Patients reported significant improvement in quality of life†† • Patients reported a significant improvement in symptoms of bloating and gas€ References 1.
    [Show full text]
  • UK Guidelines on Oesophageal Dilatation in Clinical Practice
    Gut Online First, published on February 24, 2018 as 10.1136/gutjnl-2017-315414 Guidelines UK guidelines on oesophageal dilatation in Gut: first published as 10.1136/gutjnl-2017-315414 on 24 February 2018. Downloaded from clinical practice Sarmed S Sami,1 Hasan, N Haboubi,2 Yeng Ang,3,4 Philip Boger,5 Pradeep Bhandari,6 John de Caestecker,7 Helen Griffiths,8 Rehan Haidry,9 Hans-Ulrich Laasch,10 Praful Patel,5 Stuart Paterson,11 Krish Ragunath,12 Peter Watson,13 Peter D Siersema,14 Stephen E Attwood15 ► Additional material is ABSTRACT 1.3 Obtain oesophageal biopsy specimens in published online only. To view These are updated guidelines which supersede the young patients with dysphagia or history please visit the journal online of food impaction to exclude eosinophilic (http:// dx. doi. org/ 10. 1136/ original version published in 2004. This work has gutjnl- 2017- 315414). been endorsed by the Clinical Services and Standards oesophagitis (GRADE of evidence: moder- Committee of the British Society of Gastroenterology ate; strength of recommendation: strong). For numbered affiliations see 1.4 Perform barium swallow in patients with end of article. (BSG) under the auspices of the oesophageal section of the BSG. The original guidelines have undergone suspected complex strictures (such as Correspondence to extensive revision by the 16 members of the Guideline post-radiation therapy or history of Professor Stephen E Attwood, Development Group with representation from individuals caustic injury) in order to establish the Department of Surgery, Durham across all relevant disciplines, including the Heartburn location, length, diameter and number University, Durham DH13HP, UK; Cancer UK charity, a nursing representative and a of strictures (GRADE of evidence: low; seaattwood@ gmail.
    [Show full text]
  • The GI Maladies – When and How to Treat, When to Refer Linda M
    The GI Maladies – When and How to Treat, When to Refer Linda M. Woodin, MSN, CRNP, BC Nurse Practitioner, Harrisburg Gastroenterology, Ltd. Harrisburg, PA GERD – symptoms or mucosal damage produced by the abnormal reflux of gastric contents into the esophagus PATHOPHYSIOLOGY: 1. Lower esophageal sphincter 2. Intragastric pressure 3. Poor esophageal clearance 4. Altered esophageal mucosal barrier TREAT OR TEST? 20% of patients will reflux barium on UGI (false +) PPI Precautions: o With Clopidogrel o Long-term use UGI or referral for endoscopy for: o Non-responders o > age 65 o Red-flag conditions – dysphagia, odynophagia, chest pain, weight loss, anemia, melena, hematochezia, > 1 year of symptoms, bisphosphonates, NSAIDs, low-dose ASA , history of Barrett’s esophagus NON-CARDIAC CHEST PAIN Non-cardiac chest pain requires further diagnostics – UGI and/or EGD MOST COMMON CAUSES: Erosive esophagitis Odynophagia (including pill odynophagia) (minocycline, erythromycin) Esophageal spasm Achalasia = insufficient LES relaxation with loss of esophageal peristalsis and esophageal dilation (bird-beak appearance on UGI) If normal EGD -> esophageal manometry and 24 hour esophageal pH DYSPHAGIA/ODYNOPHAGIA: Dysphagia or odynophagia requires further diagnostics – barium swallow and/or EGD MOST COMMON CAUSES: o Esophagitis o Esophageal dysmotility o Hiatal hernia o Schatzki’s ring o Achalasia (LES insufficient relaxation with esophageal dilation o Medications (bisphosphonates, tetracyclines) HELICOBACTOR PYLORI Asymptomatic, but can cause chronic gastritis, PUD, gastric cancer (MALT – Mucosal Associated Lymphoid Tissue) TESTING: H pylori antibody IGG – does not reflect acute infection o Urea breath test – reliable o H. pylori fecal antigen – reliable o Testing during EGD – culture, modified Giemsa, rapid urease TREATING: o What drugs? o How much? o How long? If active infection detected, treatment and confirmation of eradication required If eradication unsuccessful, need to change treatment regimen Treating H.
    [Show full text]
  • Removal of Esophageal Variceal Bands to Salvage Complete Esophageal Obstruction
    CASE REPORT Clin Endosc 2018;51:491-494 https://doi.org/10.5946/ce.2018.011 Print ISSN 2234-2400 • On-line ISSN 2234-2443 Open Access Removal of Esophageal Variceal Bands to Salvage Complete Esophageal Obstruction Ala’ A Abdel Jalil, Ghassan Hammoud, Jamal A Ibdah and Sami Samiullah Division of Gastroenterology & Hepatology, University of Missouri-Columbia, Columbia, MO, USA Esophageal varices develop in almost half of the patients with cirrhosis, and variceal hemorrhage constitutes an ominous sign with an increased risk of mortality. Variceal banding is considered an effective and mostly safe measure for primary and secondary prophylaxis. Although adverse events related to banding including dysphagia, stricture formation, bleeding, and ligation-induced ulcers have been described, complete esophageal obstruction is rare, with only 10 reported cases in the literature. Among those cases, 6 were managed conservatively; 1 patient had esophageal intraluminal dissection from an attempt to remove the bands using biopsy forceps but ultimately recovered with conservative management. Three patients developed strictures following removal of the bands, requiring repeated sessions of dilation therapy. We report on a patient who developed absolute dysphagia and complete esophageal obstruction after variceal banding. We successfully used the endoloop cutter hook to release the bands intact and restore luminal integrity. Clin Endosc 2018;51:491-494 Key Words: Band ligation; Cirrhosis; Dysphagia; Esophageal obstruction; Endoscopy INTroDUCTION first variceal
    [Show full text]
  • Esophageal Intramural Pseudodiverticulosis with Food Impaction
    attila_8990.qxd 1/6/2006 3:41 PM Page 37 BRIEF COMMUNICATION Esophageal intramural pseudodiverticulosis with food impaction Tan Attila MD, Norman E Marcon MD FRCPC T Attila, NE Marcon. Esophageal intramural pseudodiverticulosis Pseudodiverticulose oesophagienne intramurale with food impaction. Can J Gastroenterol 2006;20(1):37-38. avec bouchon de nourriture Esophageal intramural pseudodiverticulosis is a rare condition of La pseudodiverticulose oesophagienne intramurale est une affection rare, unknown etiology originally described in 1960. It is characterized by d’étiologie inconnue, qui a été décrite pour la première fois en 1960. Elle multiple, flask-shaped outpouchings of pinhead size in the wall of the se caractérise par une multitude de diverticules de la grosseur d’une tête esophagus. Very small outpouchings on endoscopy and tiny collec- d’épingle, en forme de fiole, qui se trouvent dans la paroi de l’œsophage. tions of barium outside of the esophagus wall on esophagography are La présence de très petits diverticules à l’endoscopie et de minuscules typical diagnostic findings. During the era of widespread endoscopic amas de baryum à l’extérieur de la paroi de l’œsophage, à l’oesophagogra- and radiological evaluation of esophageal disorders, approximately phie, est un signe diagnostique caractéristique. À l’époque où l’évaluation 200 cases were published in the literature. A 52-year-old man with endoscopique et radiologique des troubles de l’œsophage était pratique esophageal intramural pseudodiverticulosis with food impaction is courante, on a fait état d’environ 200 cas dans la documentation médi- reported. The patient’s symptoms of dysphagia resolved with endo- cale.
    [Show full text]
  • Anatomical Description During Standard Upper Endoscopy
    Resident Corner Page 1 of 2 Anatomical description during standard upper endoscopy Ahmad Najdat Bazarbashi, Kelly E. Hathorn, Marvin Ryou Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Boston, MA, USA Correspondence to: Ahmad Najdat Bazarbashi, MD. Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Boston, MA, USA. Email: [email protected]. Received: 15 January 2019; Accepted: 27 February 2019; Published: 18 March 2019. doi: 10.21037/aos.2019.03.01 View this article at: http://dx.doi.org/10.21037/aos.2019.03.01 In this video (Figure 1), we demonstrate standard upper endoscopy performed on a 50-year-old patient with history of gastroesophageal (GE) reflux disease and dyspepsia. We highlight the common anatomical landmarks of the upper Video 1. Anatomical description during gastrointestinal tract (Table 1, Figure 2) and endoscopic standard upper▲ endoscopy techniques for successful esophageal intubation, gastric Ahmad Najdat Bazarbashi*, Kelly E. Hathorn, retroflexion, duodenal access and tissue sampling using Marvin Ryou biopsy forceps. Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Essentials of endoscopic reporting Boston, MA, USA Esophagus Figure 1 Anatomical description during standard upper endoscopy (1). Z line: regular vs. irregular; Available online: http://aos.amegroups.com/post/view/1550051583 Location of GE junction from incisors (example: 40 cm); Ease of scope passage through GE junction; extension to distal extension), malignant appearing, If varices present: grade, size, location, red wale sign or anterior vs. posterior wall or lesser curvature vs. greater white nipple sign (stigmata of bleeding); curvature, extension into esophagus or GE junction, Hiatal Hernia: size, from GE junction to diaphragmatic spontaneous bleeding or contact bleeding; pinch (example 35–40 cm), Hill classification; If gastritis is present: location, patchy vs.
    [Show full text]
  • Tom Frazierfrazier Objectivesobjectives
    TomTom FrazierFrazier ObjectivesObjectives AchalasiaAchalasia EverythingEverything inin ddsepddsep Pathophysiology SomeSome extrasextras Epidemiology VideoVideo Symptomatology Diagnosis Complications Treatment PathophysiologyPathophysiology degeneration of the myenteric inhibitory neurons imbalance between excitatory and inhibitory elements Intact cholinergic, excitatory neural function ? autoimmune response to a viral insult in genetically susceptible individuals HSV/Zoster/others Circulating autoantibodies Inflammatory infiltrate class II HLA DQw1 The American Journal of Gastroenterology Vol. 100, 6 Pages: 1404-1414 The American Journal of Gastroenterology Vol. 100, 6 Pages: 1404-1414 HistopathologyHistopathology ofof AchalasiaAchalasia Mild normal inflammation Loss of Severe inflammtion ganglion cells Walzer N, Hirano I. Gastroenterology Clinics - Volume 37, Issue 4 (December 2008) SecondarySecondary formsforms ofof achalasiaachalasia Achalasia Achalasia secondary to cancer Postoperative (antireflux fundoplication, bariatric (pseudoachalasia) gastric banding) Squamous cell carcinoma of the esophagus Allgrove's syndrome (AAA syndrome) Adenocarcinoma of the esophagus Eosinophilic esophagitis Gastric adenocarcinoma Hereditary cerebellar ataxia Lung carcinoma Familial achalasia Leiomyoma Sjogren's syndrome LyLymphomamphoma Sarcoidosis Breast adenocarcinoma Post vagotomy Hepatocellular carcinoma Autoimmune polyglandular syndrome type II Reticulum cell sarcoma Lymphangiomphangioma Achalasia with generalized motility disorder
    [Show full text]
  • Surgical Treatment of Gastroesophageal Reflux Disease
    Surgical Treatment of Gastroesophageal Reflux Disease a, b Robert B. Yates, MD *, Brant K. Oelschlager, MD KEYWORDS Gastroesophageal reflux disease Laparoscopic antireflux surgery Hiatal hernia Fundoplication KEY POINTS Gastroesophageal reflux disease is abnormal distal esophageal acid exposure that results in bothersome symptoms. It is caused by the failure of endogenous antireflux barriers, including the lower esophageal sphincter and esophageal clearance mechanisms. Appropriate preoperative patient evaluation increases the likelihood that gastroesopha- geal reflux disease–related symptoms will improve after laparoscopic antireflux surgery. In patients that have a clinical history suggestive of gastroesophageal reflux disease, diag- nostic testing should include ambulatory pH monitoring, esophageal manometry, esoph- agogastroduodenoscopy, and upper gastrointestinal series. Correct construction of the fundoplication reduces the risk of postoperative dysphagia caused by an inappropriately tight fundoplication, posterior herniation of gastric fundus, and slipped fundoplication. Recurrent symptoms of gastroesophageal reflux disease should be evaluated with esophageal manometry and ambulatory pH testing. Reoperative antireflux surgery should be performed by experienced gastroesophageal surgeons. INTRODUCTION Gastroesophageal reflux disease (GERD) is the most common benign medical condition of the stomach and esophagus. GERD is defined by abnormal distal esophageal acid exposure that is associated with patient symptoms. Most patients
    [Show full text]
  • New Duration of Use and Dose Limits for Proton Pump Inhibitors (Ppis)
    New duration of use and dose limits for Proton Pump Inhibitors (PPIs) Beginning June 1, 2017, Washington Apple Health (Medicaid), administered by the Health Care Authority (Agency) will limit PPIs to one tablet/capsule per day for 2 months during any 12-month period. The Agency may authorize more than 2 months per year and/or more than one tablet/capsule per day for patients taking certain medications or who have one of the chronic medical conditions listed below: Chronic medical conditions include: Pathological gastric acid hypersecretion, such as Zollinger-Ellison syndrome Barrett’s esophagus Esophageal stenosis/stricture or Schatzki ring Recent erosive/ulcerative esophagitis or duodenal/gastric ulcer Concurrent medications include: Chronic NSAID use (including aspirin greater than or equal to 325 mg per day) Chronic low-dose aspirin with history of a GI bleed Chronic high-dose systemic steroid Antiplatelet or anticoagulant Bisphosphonate where there are pre-existing esophageal disorders Pancreatic enzyme Cancer Therapies Why are we adopting these interventions? PPIs are commonly prescribed to treat gastroesophageal reflux disease (GERD) or heartburn and symptoms are generally well controlled after 60 days of PPI therapy, even when cases are more severe. PPIs are known to cause rebound acid reflux when patients try to abruptly discontinue using the PPI. This rebound reflux is often mistaken for continued need of the PPI and has led to overutilization. Overutilization is defined as using a PPI for longer than the FDA-recommended time period of 4 to 8 weeks. To avoid rebound acid reflux the PPI should be gradually discontinued and supplemented with a histamine-2 receptor blocker (H2RA) e.g.
    [Show full text]