DOCSLIB.ORG

MULTIMODAL IMAGING, COMPUTER VISION, and AUGMENTED REALITY for MEDICAL GUIDANCE a Dissertation Presented to the Graduate Faculty

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text

Load more

MULTIMODAL IMAGING, COMPUTER VISION, AND AUGMENTED REALITY FOR MEDICAL GUIDANCE A Dissertation Presented to The Graduate Faculty of The University of Akron In Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy Christopher Andrew Mela December, 2018 MULTIMODAL IMAGING, COMPUTER VISION, AND AUGMENTED REALITY FOR MEDICAL GUIDANCE Christopher Andrew Mela Dissertation Approved: Accepted: ________________________ ________________________ Advisor Interim Department Chair Dr. Yang Liu Dr. Rebecca K. Willits ________________________ ________________________ Committee Member Interim Dean of the College Dr. Brian Davis Dr. Craig Menzemer ________________________ ________________________ Committee Member Dean of the Graduate School Dr. Rebecca K. Willits Dr. Chand Midha __________________________ __________________________ Committee Member Date Dr. Ajay Mahajan __________________________ Committee Member Dr. Yi Pang __________________________ Committee Member Dr. Jiahua Zhu ii ABSTRACT Surgery is one of the primary treatment options for many types of diseases. Traditional methods of surgical planning and intraoperative lesion identification rely on sight as well as physical palpitation of the suspect region. Since these methods are of low specificity, doctors have begun relying upon medical imaging technologies to make diagnoses and to help plan and guide surgical procedures. Preoperative imaging technologies such as Magnetic Resonance Imaging (MRI) and X-ray Computed Tomography (CT) do well to aid in diagnostics and operative planning. However, compact technologies with high specificity and resolution that are convenient for intraoperative use are needed to aid in surgical guidance. Methods including fluorescence imaging, intraoperative microscopy and ultrasound have gained significant recent attention towards these ends. Discussed in this dissertation is the initial design, construction, programming, testing and expanding of a platform technology integrating multimodal medical imaging, computer vision and augmented reality. The platform combines a real-time, head-mounted stereoscopic fluorescence imaging system in-line with a near-eye display. The compact and light-weight assembly provides the user with a wide field-of-view, line-of-sight imaging system that simulates natural binocular vision. Additionally, an ultrasound iii imaging module is connected and incorporated into the display, along with a portable fiber microscopy system. Lastly, pre-operative MRI/CT imaging models are incorporated into the system for intraoperative registration and display onto the surgical scene. Novel software algorithms were developed to enhance system operations. Fluorescence detection while using a wearable imaging platform was improved through the incorporation of an optical point tracking regime with pulsatile illumination. Optical fiducial marker identification was added to aid in ultrasound and tomographic image registration. Additionally, stereoscopic depth-of-field measurements were used towards the implementation of a fluorescence-to-color video rate co-registration scheme. System testing was conducted on multiple fronts. Fluorescence imaging sensitivity was evaluated to determine minimum detectable concentrations of fluorescent dye. Surgical and medical diagnostic simulations were also conducted using optical tissue phantoms to evaluate device performance in relation to traditional methods, and to identify areas of improvement. System resolution was also analyzed both in planar spatial coordinates as well as depth-of-field measurements. The performance of various augmented reality displays was tested with respect to fidelity of fluorescence identification and resolution. Lastly, the system was tested for registration accuracy. In summary, we have developed a platform integrating intraoperative multimodal imaging, computer vision, and augmented reality, for guiding surgeries and other medical applications. iv ACKNOWLEDGEMENTS Special thanks to my advisor Dr. Yang Liu who took me on when few others would. Thanks to my lab mates, Tri Quang and Maziyar Askari, for working with me these past few years. Thanks as well to my committee members for, well, being on my committee. I’m sure reading this will be fun. Additional acknowledgements to Stephen Paterson, Visar Berki, Drs. Forrest Bao, Vivek Nagarajan and Narrender Reddy for their technical support at various times during my time at the University of Akron. More gratitude towards Charlotte LaBelle and Sandy Vasenda for assisting with my many and varied administrative needs, as well as to Dr. Daniel Sheffer who accepted my application and was the first person to welcome me at Akron. Thanks to our clinical collaborators at the Cleveland Clinic, in particular Dr. Frank Papay who made our collaborations possible. Additional thanks to Dr. Stephen Grobmyer who kindly brought our system into the surgery, and Drs. Edward Maytin, Maria Madajka and Eliana Duraes for collaborating with us on clinical imaging research. A big thanks to NASA, William Thompson at Glenn Research Center and Baraquiel Reyna at Johnson, as well as to the whole NASA Space Technologies Research Fellowship team. v TABLE OF CONTENTS Page LIST OF TABLES………………………………………………………………………xiv LIST OF FIGURES…………………………………………………………………….xix CHAPTER I. INTRODUCTION………………………………………………………………………1 1.1. Imaging for Surgical Oncology………………………………………………1 1.2. Intraoperative Fluorescence Imaging for Surgical Interventions…………….5 1.2.1. Fluorescent Dyes……………………………………………………5 1.2.2. Fluorescence Imaging in Surgery…………………………………..8 1.2.3. Instrumentation in Fluorescence Imaging…………………………..9 1.2.4. Fluorescence Imaging Systems……………………………………11 1.3. Augmented Reality in Medical Imaging…………………………………….14 1.4. Multimodal Imaging………………………………………………………..17 1.4.1. Ultrasound…………………………………………………………17 vi 1.4.2. Radiology………………………………………………………….18 1.4.3. MRI/CT……………………………………………………………18 1.5. Scope and Aims……………………………………………………………..19 II. STEREOSCOPIC IMAGING GOGGLES FOR MULTIMODAL INTRAOPERATIVE IMAGE GUIDANCE ……………………………………….25 2.1. Introduction………………………………………………………………….25 2.2. Materials and Methods………………………………………………………28 2.2.1. Imaging System Instrumentation………………………………….28 2.2.2. Image Acquisition, Processing, Registration and Display………..32 2.2.3. System Characterization…………………………………………..34 2.2.4. Image-Guided Surgery in Chicken Ex Vivo………………………36 2.2.5. Telemedicine………………………………………………………37 2.3. Results……………………………………………………………………….38 2.3.1. System Characterization…………………………………………..38 2.3.2. Image-Guided Surgeries in Chicken………………………………41 2.3.3. Telemedicine………………………………………………………46 2.4. Discussion…………………………………………………………………...47 2.4.1. Stereoscopy………………………………………………………..48 2.4.2. Characterization…………………………………………………...48 vii 2.4.3. Microscopy………………………………………………………..49 2.4.4. Ultrasound…………………………………………………………50 2.4.5. Future Work……………………………………………………….50 2.5. Conclusions………………………………………………………………….51 III. METHODS OF CHARACTERIZATION FOR A STEREOSCOPIC HEAD- MOUNTED FLUORESCENCE IMAGING SYSTEM……………………………….52 3.1. Introduction………………………………………………………………….52 3.2. Materials and Methods………………………………………………………57 3.2.1. Optical Imaging and Display……………………………………..57 3.2.2. Computation……………………………………………………….59 3.2.3. Fluorescence Detection Sensitivity……………………………….59 3.2.4. Fluorescence Guided Surgical Simulation………………………..64 3.2.5. Resolution Testing………………………………………………..67 3.2.6. Display Testing…………………………………………………….69 3.3. Results……………………………………………………………………….70 3.3.1. Fluorescence Detection Sensitivity……………………..............70 3.3.2. Fluorescence Guided Surgical Simulation………………………..76 3.3.3. Resolution Testing…………………………………………………77 3.3.4. Display Testing……………………………………………………78 viii 3.4. Discussion…………………………………………………………………..81 5.4.1. Dark Room Study…………………………………………………81 5.4.2. Tissue Phantom Study…………………………………………….82 5.4.3. Display Testing……………………………………………………84 3.5. Conclusions………………………………………………………………….85 IV. APPLICATION OF A DENSE FLOW OPTICAL TRACKING ALGORITHM WITH PULSED LIGHT IMAGING FOR ENHANCED FLUORESCENCE DETECTION ………………………………………………………………………….86 4.1. Introduction………………………………………………………………….86 4.1.1. Enhancing Fluorescence Imaging for Clinical Application……….86 4.1.2. Pulsed Light Imaging for Skin Cancer Therapy…………………..90 4.2. Materials and Methods………………………………………………………92 4.2.1. Computation……………………………………………………….92 4.2.2. Instrumentation……………………………………………………92 4.2.3. Illumination………………………………………………………..93 4.2.4. Fluorescent Point Tracking………………………………………..96 4.2.5. Fluorescence Sensitivity………………………………………….97 4.2.6. Fluorescent Point Tracking Accuracy ………………………......98 4.3. Results……………………………………………………………………..101 4.3.1. Pulsed Light Imaging…………………………………………….101 ix 4.3.2. Fluorescent Point Tracking Accuracy……………………………103 4.3.3. Fluorescence Sensitivity………………………………………...104 4.4. Discussion………………………………………………………………….106 4.4.1. Pulsed Light Imaging…………………………………………….106 4.4.2. Fluorescent Point Tracking Accuracy……………………………107 4.4.3. Fluorescence Sensitivity…………………………………………108 4.5. Conclusions…………………………………………………………….....109 V. MULTIMODAL IMAGING GOGGLE WITH AUGMENTED REALITY COMBINING FLUORESCENCE, ULTRASOUND AND TOMOGRAPHICAL IMAGING………………………………………………………………………..111 5.1. Introduction………………………………………………………………..111 5.1.1. Single and Multimode Imaging………………………………….111 5.1.2. Multimodal Image Registration………………………………….112 5.1.3. Augmented Reality Fluorescence Imaging System with Multimode Registration…………………………………………………………..116 5.2. Materials and Methods…………………………………………………….117 5.2.1. Optical
Recommended publications
  • Stereo Capture and Display At

    Stereo Capture and Display At

    Creation of a Complete Stereoscopic 3D Workflow for SoFA Allison Hettinger and Ian Krassner 1. Introduction 1.1 3D Trend Stereoscopic 3D motion pictures have recently risen to popularity once again following the success of films such as James Cameron’s Avatar. More and more films are being converted to 3D but few films are being shot in 3D. Current available technology and knowledge of that technology (along with cost) is preventing most films from being shot in 3D. Shooting in 3D is an advantage because two slightly different images are produced that mimic the two images the eyes see in normal vision. Many take the cheaper route of shooting in 2D and converting to 3D. This results in a 3D image, but usually nowhere near the quality as if the film was originally shot in 3D. This is because a computer has to create the second image, which can result in errors. It is also important to note that a 3D image does not necessarily mean a stereo image. 3D can be used to describe images that have an appearance of depth, such as 3D animations. Stereo images refer to images that make use of retinal disparity to create the illusion of objects going out of and into the screen plane. Stereo images are optical illusions that make use of several cues that the brain uses to perceive a scene. Examples of monocular cues are relative size and position, texture gradient, perspective and occlusion. These cues help us determine the relative depth positions of objects in an image. Binocular cues such as retinal disparity and convergence are what give the illusion of depth.
  • Fluorescein Angiography Findings in Both Eyes of a Unilateral Retinoblastoma Case During Intra-Arterial Chemotherapy with Melphalan

    Fluorescein Angiography Findings in Both Eyes of a Unilateral Retinoblastoma Case During Intra-Arterial Chemotherapy with Melphalan

    Int J Ophthalmol, Vol. 12, No. 12, Dec.18, 2019 www.ijo.cn Tel: 8629-82245172 8629-82210956 Email: [email protected] ·Letter to the Editor· Fluorescein angiography findings in both eyes of a unilateral retinoblastoma case during intra-arterial chemotherapy with melphalan Cem Ozgonul1, Neeraj Chaudhary2, Raymond Hutchinson3, Steven M. Archer1, Hakan Demirci1 1Department of Ophthalmology and Visual Sciences, W.K. was inserted into the left femoral artery, advanced into the Kellogg Eye Center, MI 48105, USA internal carotid and up to the origin of the ophthalmic artery. 2Department of Radiology, University of Michigan, MI 48109, Once the catheter tip position was confirmed at the origin USA of the ophthalmic artery by fluoroscopy, 5 mg melphalan 3Department of Pediatric Hematology/Oncology, University of was infused in a pulsatile fashion over 30min. There was Michigan, MI 48109, USA no anatomical variant of orbital vascular structure. During Correspondence to: Hakan Demirci. Department of the 2nd IAC, following the infusion of melphalan, sodium Ophthalmology and Visual Science, W.K. Kellogg Eye Center, fluorescein dye at a dose of 7.7 mg/kg was injected through the 1000 Wall St, Ann Arbor, MI 48105, USA. hdemirci@med. same microcatheter. Real-time FA was recorded by using the umich.edu RetCam III (Clarity Medical Systems, Pleasanton, California). Received: 2018-11-01 Accepted: 2019-04-09 FA was repeated 4wk later during the 3rd IAC in the same manner, before infusion of the chemotherapy. In both sessions, DOI:10.18240/ijo.2019.12.24 there was no catheterization or injection of contrast material into the untreated carotid and ophthalmic artery.
  • Risk Factors for Adverse Reactions of Fundus Fluorescein Angiography

    Risk Factors for Adverse Reactions of Fundus Fluorescein Angiography

    Original Article Risk factors for adverse reactions of fundus fluorescein angiography Yi Yang1, Jingzhuang Mai2, Jun Wang1 1Department of Ophthalmology, 2Epidemiology Division, Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangzhou 510080, China Contributions: (I) Conception and design: All authors; (II) Administrative support: All authors; (III) Provision of study materials or patients: Y Yang; (IV) Collection and assembly of data: All authors; (V) Data analysis and interpretation: Y Yang, JZ Mai; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Yi Yang. Department of Ophthalmology, Guangdong General Hospital, #106, Zhongshan Second Road, Guangzhou 510080, China. Email: [email protected]. Background: To explore the difference between the outcomes of correlations between a series of variables and adverse reactions (ARs) to fluorescein from univariate and multivariate analysis and to evaluate the nausea effects in different age groups. Methods: A retrospective study of patients undergoing consecutive fluorescein angiography between March 2010 and February 2012 was conducted. No patients were excluded on the ground of age, presence of atopy, allergy history, previous procedures without severe allergic ARs, asymptomatic hypertension and kidney failure with serum creatinine levels lower than 250 μmol/L or with renal dialysis. Results: A total of 829 patients were enrolled and 22.2% of them had ARs. The majority of reactions were nausea (12.1%) which occurred less when age became old (P<0.0001). When the correlations between a series of variables and ARs were assessed separately, age (P<0.0001), prior reactions (P<0.0001) and motion sickness (P=0.0062) were highly and cardio/cerebrovascular disease (P=0.0015), diabetes (P=0.0001) and renal disease (P=0.0219) were lowly related to ARs.
  • Spring Programme 2011

    Spring Programme 2011

    Faculty of Radiologists Royal College of Surgeons in Ireland Combined Spring Meeting 8th & 9 th April 2011 Venue: Castlemartyr Hotel, Co. Cork. Programme Faculty of Radiologists, Royal College of Surgeons in Ireland CPD Credits Awarded: 5 Royal College of Radiologists credits are applied for. Friday 8 th April 2011 3.30-4.30pm Registration 4.30-5.30pm Stroke in 2011, Moderator: Dr. Ian Kelly, Waterford Regional Hospital 4.30-5.00pm Acute Stoke Imaging. Dr Noel Fanning, Cork University Hospital, Cork 5.00-5.30pm Stroke: A clinical perspective. Dr. George Pope, John Radcliffe Hospitals, Oxford 5.30-6.30pm Moderator: Dr. Adrian Brady, Dean, Faculty of Radiologists Belfast to Bosnia and Autopsy to Virtopsy Dr. Jack Crane, State Pathologist, NI 8pm Dinner Saturday 9 th April 2011 8.30-9.00am Registration 9.00-10.00am Liver hour. Moderator: Dr John Feeney, AMNCH, Dublin 9.00-9.30am Liver imaging pre metastatectomy. Dr. Peter MacEneaney, Mercy University Hospital, Cork 9.30-10.00am Parenchymal and focal liver biopsy - when and how. Dr Stephen J Skehan St Vincent's University Hospital, Dublin 10.00-11.00am Paediatric Hour. Moderator: Dr. Stephanie Ryan, The Children’s University Hospital Temple Street, Dublin 10.00-10.30am Paediatric Abdominal Emergencies. Dr Eoghan Laffan, The Children’s, University Hospital Temple Street, Dublin 10.30-11.00am Non Accidental Injury. Dr Conor Bogue, Cork University Hospital, Cork 11.00-11.30am Tea/Coffee Break and Poster Exhibition 11.30-12.30pm MSK Hour. Moderator: Dr Orla Buckley, AMNCH, Dublin 11.30-12.00pm Image guided joint interventions.
  • National Correct Coding Initiative's (Ncci) General

    National Correct Coding Initiative's (Ncci) General

    NATIONAL CORRECT CODING INITIATIVE’S (NCCI) GENERAL CORRESPONDENCE LANGUAGE AND SECTION-SPECIFIC EXAMPLES (FOR NCCI PROCEDURE TO PROCEDURE (PTP) EDITS AND MEDICALLY UNLIKELY EDITS (MUE)) EFFECTIVE: April 1, 2017* *INCLUDES 2017 HCPCS/CPT CODES Current Procedural Terminology (CPT) codes, descriptions and other data only are copyright 2016 American Medical Association. All rights reserved. CPT® is a registered trademark of the American Medical Association. Applicable FARS\DFARS Restrictions Apply to Government Use. Fee schedules, relative value units, conversion factors and/or related components are not assigned by the AMA, are not part of CPT, and the AMA is not recommending their use. The AMA does not directly or indirectly practice medicine or dispense medical services. The AMA assumes no liability for the data contained or not contained herein. TABLE OF CONTENTS Section Page Introduction 5 General Correspondence Language for NCCI PTP Edits and Medically Unlikely Edits (MUEs) Standard preparation/monitoring services for anesthesia 8 HCPCS/CPT procedure code definition 8 CPT Manual or CMS manual coding instruction 8 Mutually exclusive procedures 9 Sequential procedure 9 CPT “Separate procedure” definition 9 More extensive procedure 9 Gender-specific procedures 10 Standards of medical/surgical practice 10 Anesthesia service included in surgical procedure 10 Laboratory panel 10 Deleted/modified edits for NCCI 11 Misuse of column two code with column one code 11 Medically Unlikely Edits (MUE) (Units of Service) 11 Deleted/modified edits
  • Virtopsy and Living Individuals Evaluation Using Computed

    Virtopsy and Living Individuals Evaluation Using Computed

    Virtopsy and Living Individuals Evaluation Using Computed Tomography in Forensic Diagnostic Imaging Giuseppe Lo Re, MD, Sergio Salerno, MD, Maria Chiara Terranova, MD Antonella Argo, MD, Antonio Lo Casto, MD, Stefania Zerbo, MD, and Roberto Lagalla, MD The applications of forensic radiology involve both Virtopsy both studies on living people À to demonstrate bone age, search for foreign bodies, such as voluntary injection of drug ovules or surgical sponges accidentally forgotten, to assess gunshot wounds, to evaluate injuries by road accidents, and cases of violence or abuse (both in adults and in children). Computed tomography is the most used imaging tool used in forensic pathology and its indications are mainly focused on cases of unnatural deaths or when a crime is suspected. It is preferred over the standard autopsy in selected cases, such as in putrefied, carbonized or badly damaged bodies; or as a preliminary evaluation in mass disasters. Semin Ultrasound CT MRI 40:67-78 © 2018 Elsevier Inc. All rights reserved. Introduction also preserving evidence in an undisturbed state. Diag- nostic imaging plays a pivotal role in the preliminary he applications of forensic radiology (FR) involve both evaluation in the “safety screening” prior to forensic À T studies on living people and cadavers to demonstrate assessment of the remains; thus, preventing dangers to bone age, search for foreign bodies, such as voluntary injec- the workers who handle the corpses, or in case of infec- tion of drug ovules or surgical sponges accidentally forgot- tion surveillance, such as pulmonary tuberculosis, con- ten, to assess gunshot wounds, to evaluating injuries by road firmed by CT examination before autopsy.16-18 accidents and cases of violence or abuse (both in adults and Although the costs and availability of CT scanners and 1-3 in children).
  • 2Nd Quarter 2001 Medicare Part a Bulletin

    2Nd Quarter 2001 Medicare Part a Bulletin

    In This Issue... From the Intermediary Medical Director Medical Review Progressive Corrective Action ......................................................................... 3 General Information Medical Review Process Revision to Medical Record Requests ................................................ 5 General Coverage New CLIA Waived Tests ............................................................................................................. 8 Outpatient Hospital Services Correction to the Outpatient Services Fee Schedule ................................................................. 9 Skilled Nursing Facility Services Fee Schedule and Consolidated Billing for Skilled Nursing Facility (SNF) Services ............. 12 Fraud and Abuse Justice Recovers Record $1.5 Billion in Fraud Payments - Highest Ever for One Year Period ........................................................................................... 20 Bulletin Medical Policies Use of the American Medical Association’s (AMA’s) Current Procedural Terminology (CPT) Codes on Contractors’ Web Sites ................................................................................. 21 Outpatient Prospective Payment System January 2001 Update: Coding Information for Hospital Outpatient Prospective Payment System (OPPS) ......................................................................................................................... 93 he Medicare A Bulletin Providers Will Be Asked to Register Tshould be shared with all to Receive Medicare Bulletins and health care
  • Bilateral Exudative Retinal Detachment in a Patient with Cerebral Venous Sinus Thrombosis: a Case Report

    Bilateral Exudative Retinal Detachment in a Patient with Cerebral Venous Sinus Thrombosis: a Case Report

    Bilateral exudative retinal detachment in a patient with cerebral venous sinus thrombosis: a case report Liang Li The second Xiangya Hospital, Central South University Ling Gao ( [email protected] ) Second Xiangya Hospital https://orcid.org/0000-0002-9850-2038 Case report Keywords: exudative retinal detachment, cerebral venous sinus thrombosis, elschnig spot, retinal capillary ischemia Posted Date: June 6th, 2019 DOI: https://doi.org/10.21203/rs.2.9789/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 1/8 Abstract Background: Cerebral venous sinus thrombosis (CVST) is a rare cerebrovascular disease, it’s ocular symptoms often characterized by a subacute bilateral visual loss, or diplopia and paralysis of eye movements. Fundus examination usually presents as bilateral papilledema and other ocular signs are rare. We report a case of bilateral multiple retinal detachments and nally diagnosed as CVST. Case presentation: A 49-year old woman with progressive headache and bilateral vision deterioration visited our clinic. Ophthaomological examinations including medical history, best-corrected visual acuity, intraocular pressure, slit-lamp biomicroscopy, fundus ophthalmoscopy, uorescein angiography and Optical coherence tomography and head Magnetic Resonance Venogram (MRV) was also performed. Blood tests for ruling out systemic diseases were also performed. Fundus exam revealed bilateral multiple retinal detachment with sub-retinal uid and blurred disc margin. Fluorescein angiography (FA) revealed early hypouorescence in the background stage, multiple pinpoint leakages at the level of retinal pigment epithelium (RPE), and late pooling to outline the boundary of retinal detachment, with some of the leakage shaped as multiple circles in the late stage of FA.
  • Fast-Response Switchable Lens for 3D and Wearable Displays

    Fast-Response Switchable Lens for 3D and Wearable Displays

    Fast-response switchable lens for 3D and wearable displays Yun-Han Lee, Fenglin Peng, and Shin-Tson Wu* CREOL, The College of Optics and Photonics, University of Central Florida, Orlando, Florida 32816, USA *[email protected] Abstract: We report a switchable lens in which a twisted nematic (TN) liquid crystal cell is utilized to control the input polarization. Different polarization state leads to different path length in the proposed optical system, which in turn results in different focal length. This type of switchable lens has advantages in fast response time, low operation voltage, and inherently lower chromatic aberration. Using a pixelated TN panel, we can create depth information to the selected pixels and thus add depth information to a 2D image. By cascading three such device structures together, we can generate 8 different focuses for 3D displays, wearable virtual/augmented reality, and other head mounted display devices. ©2016 Optical Society of America OCIS codes: (230.3720) Liquid-crystal devices; (080.3620) Lens system design. References and links 1. O. Cakmakci and J. Rolland, “Head-worn displays: a review,” J. Display Technol. 2(3), 199–216 (2006). 2. B. Furht, Handbook of Augmented Reality (Springer, 2011). 3. H. Ren and S. T. Wu, Introduction to Adaptive Lenses (Wiley, 2012). 4. K. Akeley, S. J. Watt, A. R. Girshick, and M. S. Banks, “A stereo display prototype with multiple focal distances,” ACM Trans. Graph. 23(3), 804–813 (2004). 5. S. Liu and H. Hua, “A systematic method for designing depth-fused multi-focal plane three-dimensional displays,” Opt. Express 18(11), 11562–11573 (2010).
  • New Phase in Forensic Odontology

    New Phase in Forensic Odontology

    International Journal of Dental and Health Sciences Review Article Volume 02,Issue 06 VIRTOPSY: NEW PHASE IN FORENSIC ODONTOLOGY Yogish.P 1, Asha Yogish 2 1.Assisstant Professor in Department of Oral Pathology and Microbiology, Sharavathi Dental College and Hospital, Shivamogga. 2.Postgraduate student in Department of Oral Medicine and Radiology, Coorg Institute of Dental Sciences, Virajpet. ABSTRACT: Nowadays, technological advances are becoming more and more important in forensic sciences. Yet autopsy is still one of the very traditional methods. This also applies for dental autopsies, in which visual, photographic and radiological evidences are collected. Virtual Autopsy appears as a helpful and complementary tool for dental and medical cadaveric examination. Using high-tech radiological approaches, Virtual Autopsy may provide, through images, an efficient and more accurate view on the individual case. This critical review aims to update on the origin, applications of virtopsy and also the role of dentists in this field. Keywords: Autopsy; Radiology; Forensic Odontology INTRODUCTION: Death is an inevitable part of life and at psychiatry and behavioural science, few occasions scientific examination of questioned documents, toxicology and bodies after death becomes mandatory. physical anthropology. Modern day investigations have reached a point of sophistication interconnecting Forensic pathology is a discipline of the involvement of many different Forensic science which deals with disciplines to serve problems including pathologic and
  • Introduction

    Introduction

    RIMS, IMPHAL ANNUAL REPORT 2014-15 INTRODUCTION 1. DESCRIPTION : The Regional Institute of Medical Sciences (RIMS), Imphal was established in the year 1972. It is an institution of regional importance catering to the needs of the North Eastern Region in the field of imparting undergraduate and post graduate medical education.The Institution brings together educational facilities for the training of personnel in all important branches of medical specialities including Dental and Nursing education in one place. The Institute is affiliated to the Manipur University, Canchipur, Imphal. 2. MANAGEMENT : The Institute was transferred to the Ministry of Health & Family Welfare, Government of India from North Eastern Council, Shillong (under Ministry of DoNER, Government of India) w.e.f. 1st April, 2007. Under the existing administrative set-up, the highest decision making body is the Board of Governors headed by the Union Minister of Health & Family Welfare as the President and the Director of the Institute as the Secretary. The Executive Council is responsible for the management of the Institute. The Secretary, Ministry of Health & Family Welfare, Government of India is the Chairman of the Executive Council while the head of the Institute remains as Secretary. Thus, the institute is managed at two levels, namely the Board of Governors and the Executive Council. A. Board of Governors : 1. Hon’ble Union Minister, - President Health & Family Welfare, Government of India. 2. Hon’ble Chief Minister, Manipur. - Vice-President 3. A Representative of the Planning Commission, - Member Government of India. 4. Health Ministers of the Beneficiary States - Member 5. Secretary, Ministry of Health & Family Welfare, - Member Government of India.
  • Initial Observations Comparing MDCT and 3.0T MRI Findings with Autopsy Findings

    Initial Observations Comparing MDCT and 3.0T MRI Findings with Autopsy Findings

    Utility of Postmortem Autopsy via Whole- Body Imaging: Initial Observations Comparing MDCT and 3.0T MRI Findings with Autopsy Findings Jang Gyu Cha, MD1 Dong Hun Kim, MD1 Objective: We prospectively compared whole-body multidetector computed Dae Ho Kim, MD2 tomography (MDCT) and 3.0T magnetic resonance (MR) images with autopsy Sang Hyun Paik, MD1 findings. Jai Soung Park, MD1 Materials and Methods: Five cadavers were subjected to whole-body, 16- Seong Jin Park, MD1 channel MDCT and 3.0T MR imaging within two hours before an autopsy. A radi- Hae Kyung Lee, MD1 ologist classified the MDCT and 3.0T MRI findings into major and minor findings, Hyun Sook Hong, MD1 which were compared with autopsy findings. 3 Duek Lin Choi, MD Results: Most of the imaging findings, pertaining to head and neck, heart and 4 Kyung Moo Yang, MD vascular, chest, abdomen, spine, and musculoskeletal lesions, corresponded to 4 Nak Eun Chung, MD autopsy findings. The causes of death that were determined on the bases of 4 Bong Woo Lee, MD MDCT and 3.0T MRI findings were consistent with the autopsy findings in four of 4 Joong Seok Seo, MD five cases. CT was useful in diagnosing fatal hemorrhage and pneumothorax, as well as determining the shapes and characteristics of the fractures and the direc- Index terms: tion of external force. MRI was effective in evaluating and tracing the route of a Computed tomography (CT) metallic object, soft tissue lesions, chronicity of hemorrhage, and bone bruises. Magnetic resonance (MR) Whole-body imaging Conclusion: A postmortem MDCT combined with MRI is a potentially powerful Forensic autopsy tool, providing noninvasive and objective measurements for forensic investiga- DOI:10.3348/kjr.2010.11.4.395 tions.