Indian Journal of Biotechnology Vol 12, January 2013, pp i-iv

Supplementary Matter:

Table S1—Top 10 differentially expressed

Table S2—List of up regulated genes with their product

Accession ID Reporter Gene product

W68291;W68403 1 R06263;R06321 4 Hydroxymethylbilane synthase AA130187; AA130278 9 Wilms tumor 1 R87763; R87840 6 Intercellular adhesion molecule 5, telencephalin AA425900 10 Uracil-DNA 2 R83223; R83224 8 Ras and Rab interactor 2 AA416890; AA469896 13 Sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) AA629591 12 Testis enhanced gene transcript (BAX inhibitor 1) AA669359 16 Ribosomal protein L36a-like R66139;R67753 18 Chemokine (C-X3-C motif) ligand 1 N66208;N99208 20 Protein phosphatase 1, regulatory (inhibitor) subunit 8 AA977094 28 N64014 19 Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha AA678335 22 AI261807 34 AI000188 31 AI298976 36 Chemokine (C motif) ligand 2 AI300241 35 Myogenic factor 3 AI017508 42 AI350226 38 Suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) AA954967 41 AI269361 45 AI923692 53 AI347137 48 Discs, large (Drosophila) homolog-associated protein 4 AA424747;AA424871 65 AA436152;AA436278 68 Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A N80949;N68256 63 Lipase, hepatic AA055811;AA055862 69 Glycoprotein A33 (transmembrane) N91990;N63845 72 Phytanoyl-CoA hydroxylase (Refsum disease) N68327 73 Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 T61078;T61180 86 Carbamoyl-phosphate synthetase 1, mitochondrial R22624;R22625 92 Cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) (ii) INDIAN J BIOTECHNOL, JANUARY 2013

Table S3—List of top down regulated genes with their gene product

Accession ID Reporter Gene product

H78560;H79047 2 H18070 3 Mitochondrial translational initiation factor 2 H77651;H77652 5 GATA binding protein 6 AA455145;AA464328 7 Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B AA099153;AA099251 11 Tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) AA086471;AA112727 15 H46254;H46316 14 Solute carrier family 6 (neurotransmitter transporter, GABA), member 1 AA055584;AA055585 17 Kruppel-like factor 6 AA071235;AA071486 21 Aurora kinase B AA035383;AA035384 23 Succinate dehydrogenase complex, subunit D, integral membrane protein AA931884 26 AA677655 24 Klotho AA988746 29 WD repeat and SOCS box-containing 2 AA953508 25 AI014441 30 Tumor protein D52-like 1 AA971406 27 KIAA0241 protein AI005540 32 KIAA0261 AI244615 33 AI146610 43 Sterile alpha motif domain containing 4 AI300907 37 Hypothetical protein LOC201191 AI371874 47 AI346457 40 Pleiomorphic adenoma gene-like 2 AI049531 44 AI873645 50 Cyclin-dependent kinase 5 AI860008 49 Interleukin 15 AI890760 51 AI922893 54 AI936324 55 AI924973 52 AA031513;AA031514 61 Matrix metalloproteinase 7 (matrilysin, uterine) AA455941;AA456408 60 N-acylaminoacyl-peptide R19952;R45056 57 Protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) AI926993 56 Acid phosphatase, prostate T69284;T69359 62 Mannose-binding lectin (protein C) 2, soluble (opsonic defect) AA458503;AA442995 59 Nuclear receptor interacting protein 1 AA427717;AA429281 67 N52474;N75691 58 Folate hydrolase (prostate-specific membrane antigen) 1 AA017382;AA017383 70 Staphylococcal nuclease domain containing 1 AA418077;AA418223 66 GTP binding protein overexpressed in skeletal muscle H20856;H20908 81 Excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) R43734 64 Laminin, alpha 4 T62482;T62627 80 SP110 nuclear body protein AA485141 78 Src-like-adaptor T71878;T71879 83 Complement component 2 AA279147 84 Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) AA436871;AA442629 75 Syntaxin 3A N98563;W24246 77 Interferon-induced protein with tetratricopeptide repeats 5 AA233549;AA233663 82 D component of complement (adipsin) KHURANA-KAUL et al.: GENETIC DIVERSITY IN J. CURCAS L. (iii)

Table S3—List of top down regulated genes with their gene product

Accession ID Reporter Gene product

AA489602;AA497020 74 TNF receptor-associated protein 1 AA036974;AA036975 79 Amine oxidase, copper containing 3 (vascular adhesion protein 1) AA279755;AA279883 88 CD69 antigen (p60, early T-cell activation antigen) AA489785;AA489918 76 AA987573 97 Proteasome (prosome, macropain) 26S subunit, ATPase, 3 R12237;R39954 71 Discs, large homolog 4 (Drosophila) AA455521;AA464403 89 E2F transcription factor 5, p130-binding AA043227;AA043228 95 Calponin 3, acidic AW009108 117 AA668959 96 Protein kinase, cGMP-dependent, type I AA922917 99 Dystonin AA879118 102 AI016726 100 9 open reading frame 23 AA036881 94 Chemokine (C-C motif) receptor 1

Fig. S1—RG Density plot of 20 arrays of probe level data before normalization

Fig. S2—RG Density plot of 20 arrays of probe level data after normalization (iv) INDIAN J BIOTECHNOL, JANUARY 2013

Fig. S3—MA plots of 20 arrays of probe level data after normalization