Archives of Clinical Case Studies and Case Reports

Short Communication **Corresponding author Eyal Levit, MD, FFAD, FACMS, Associate Clinical Pro- fessor of Dermatology Columbia University, College of Physicians and Surgeons, Department of Dermatology, NY, USA

Lennox Ksido, Sophia K Levit, Michelle J Volis and Eyal Levit* Received: 03 Nov 2020 Accepted: 11 Nov 2020 Associate Clinical Professor of Dermatology Columbia University, College Published: 17 Nov 2020 of Physicians and Surgeons, Department of Dermatology, NY, USA Copyright © 2020 Eyal Levit OPEN ACCESS

Prevalence Cholinergic Urticaria is seen in 0.2% of the general population (usually in young adults) and accounts for about 11% of all urticaria types. It is predominantly found in males. Age of Onset The individuals often diagnosed are between the ages of ten to thirty years old. Triggers It is triggered by increased body temperature, exercise, sweating, and emotional stress. Morphology The rash appears as 1-4 millimeter lasting for about 15-60 minutes. Location Cholinergic urticaria is often found on the trunk and limbs of individuals. Symptoms Figure 1: A 31 year old male patient came in with no signs of a rash Symptoms may include burning, itching, tingling, and a warm sensation. Treatment Treatments vary and the conditions improve with time. Treatments in- clude a low diet, H1/H2 blockers, Botox, sweat reducing med- ications, UVB light, cooling skin, beta blockers, immunosuppressant’s, desensitization (regular exercise, autologous sweat), and an EpiPen in the case of . Subtypes Subtypes include idiopathic urticaria, sweat , pore occlusion, and . Prognosis There is a slow resolution over a number of years.

Figure 2: The patient performed physical exercise for three minutes and the temperature of the examination room was raised

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Figure 3: A rash formed after increasing the body temperature through physical activity Figure 5: Summarized table of cholinergic urticaria References 1. Alsamarai A, M Hasan AA, Alobaidi AH (2012) Evaluation of differ- ent combined regimens in the treatment of cholinergic urticaria. The World Allergy Organization journal 55: 88-93. 2. Marina Abajian, Nicole Schoepke, et al. (2014) Physical Urticarias and Cholinergic Urticaria Immunology and Allergy Clinics of North America 34: 73-88.

Figure 4: The gentlemen had acquired hyperhidrosis, a factor often fol- lowed by cholinergic urticaria after exercising for a couple of minutes. The rash appeared as a minute 1-4 millimeter red papules surrounded by a white halo.

Cite* this article: Lennox Ksido, Sophia K Levit, Michelle J Volis and Eyal Levit (2020) Cholinergic Urticaria. Archives of Clinical Case Studies and Case Reports 1: 99-100.

*Copyright: ©2020 Eyal Levit. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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