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Substance Activity

Substance Activity

2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance.

SUBSTANCE ACTIVITY

1- Anabolic (Addition for 2019) 3β-Hydroxy-5α-androstan-17-one Anabolic (Addition for 2019) 4-chlorometatandienone Anabolic (Addition for 2019) 5α-Androst-2-ene-17one Anabolic (Addition for 2019) 5α-Androstane-3α, 17α-diol Anabolic (Addition for 2019) 5α-Androstane-3α, 17β-diol Anabolic (Addition for 2019) 5α-Androstane-3β, 17α-diol Anabolic (Addition for 2019) 5α-Androstane-3β, 17β-diol Anabolic (Addition for 2019) 5β-Androstane-3α, 17β-diol Anabolic (Addition for 2019) 7α-Hydroxy-DHEA Anabolic (Addition for 2019) 7β-Hydroxy-DHEA Anabolic (Addition for 2019) 7-Keto-DHEA Anabolic (Addition for 2019) 17-Alpha-Hydroxy MALES Anabolic 19-Norandrosterone Anabolic (Addition for 2019) 19-Noretiocholanolone Anabolic (Addition for 2019) 20-Hydroxyecdysone Anabolic (Addition for 2019) Δ1- Anabolic (Addition for 2019) Acebutolol Beta blocker Acefylline Bronchodilator Acemetacin Non-steroidal anti-inflammatory Acenocoumarol Anticoagulant Acetanilid /antipyretic Pancreatic Acetophenazine Acetophenetidin (Phenacetin) Analgesic Acetylmorphine Adiphenine Antispasmodic Adrafinil Stimulant

30 November 2018 - Lausanne, 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Adrenochrome Haemostatic AICAR Anabolic Alclofenac Non-steroidal anti-inflammatory drug Alcuronium Aldosterone Hormone Alendronate Bisphosphonates (Addition for 2019) Narcotic Allopurinol Xanthine oxidase inhibitor (anti-hyperuricaemia)

Almotriptan 5-hydroxatryptamine (antimigraine) Alphadolone acetate Alphaprodine analgesic Anxiolytic Anxiolytic Alprenolol Beta blocker Althesin IV anaesthetic Althiazide Diuretic Alverine Antispasmodic Ambenonium Cholinesterase inhibition Ambucetamide Antispasmodic Amfepramone Stimulant Amfetaminil Stimulant Amidephrine Vasoconstrictor Diuretic Amineptine Tricyclic Aminoglutehthamide Aromatase inhibitor Aminoheptane Vasopressor Aminomethylbenzoic acid Anti-fibrinolytic Aminopicoline synthase inhibitor Aminopromazine Antispasmodic Aminopterin Immunosuppressant Amiphenazole Stimulant

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Amisometradine Diuretic Amisulpride Antipsychotic Amitriptylline Antihypertensive Ammonium Chloride (injection) Acidifying agent Ammonium Sulphate Nerve-blocking agent Ammonium Sulphide Nerve-blocking agent Amodiaquine Antimalarial Amopyroquine Antimalarial Tricyclic antidepressant Amperozide Antipsychotic Stimulant Amphetaminil Stimulant Ampyrone Non-steroidal anti-inflammatory drug Amrinone Vasodilator Amyl nitrate/nitrite Angina treatment Local anaesthetic Esters Anabolic (Addition for 2019) Anastrozole Aromatase inhibitor Andarine Selective Androgen Modulator Anabolic (Addition for 2019) Androstenediol Anabolic Androstenedione Anabolic Androsterone Anabolic (Addition for 2019) Anileridrine Opioid analgesic Central Nervous System stimulant Anisindione Anticoagulant Anisotropine Anticholinergic Antipyrine Non-steroidal anti-inflammatory drug Apazone (Azapropazone) Non-steroidal anti-inflammatory drug Apocodeine Opioid analgesic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Apomorphine Opioid analgesic Anti-arrhythmic Sedative Apronalide Sedative Arecoline Stimulant Argon Hypoxia Inducible Factor (HIF) Activator (Addition for 2019) Arsenic Stimulant/toxic Local anaesthetic Atenolol Beta blocker Selective noradrenaline re-uptake inhibitor Atracurium Muscle relaxant Azacyclonal Antipsychotic Azaperone Sedative Azapetine Vasodilator Azapropazone (Apazone) Non-steroidal anti-inflammatory drug Azathioprine Immunosuppressant Azosemide Diuretic (Addition for 2019) Antispasmodic Bambuterol Bronchodilator Bamifylline Bronchodilator Sedative Beclamide Sedative Stimulant Benactyzine Anticholinergic Benapryzine Anticholinergic Benazepril Antihypertensive Bendroflumethazide Diuretic Benorilate Non-steroidal anti-inflammatory drug Benoxaprofen Non-steroidal anti-inflammatory drug Benoxinate Local anaesthetic Benperidol Antipsychotic Anxiolytic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Sedative Benzonatate Antitussive Benzoylecgonine Stimulant/ metabolite Benzphetamine Stimulant Benzthiazide Diuretic Benztropine Anticholinergic Benzylpiperazine Stimulant blocker Betaprodine Opioid analgesic Betaxolol Beta blocker Bethanidine Antihypertensive Biperiden Anticholinergic Biphenamine Non-steroidal anti-inflammatory drug Biriperone Antipsychotic Bisoprolol Beta blocker Bitolterol Bronchodilator Bolandiol Anabolic Bolasterone Anabolic Boldenone Anabolic. Threshold substance: 0.015 micrograms free and conjugated boldenone per millilitre in urine from male Horses (other than geldings).

Boldione Anabolic Anti-arrhythmic Brimonidine Occular antihypertensive Bromantan Stimulant Anxiolytic Bromfenac Non-steroidal anti-inflammatory drug Bromisovalum Sedative Bromocriptine agonist Bromophenethylamine Psychedelic Bromperidol Antipsychotic Anxiolytic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Bucetin Analgesic/antipyretic Bufexamac Non-steroidal anti-inflammatory drug Buflomedil Vasoactive agent Bufotenine (Specified Substance) Naturally occurring Diuretic Bunitrolol Beta adrenergic antagonist Bunolol Beta blocker Buphenine (Nylidrin) Sympathomimetic Bupranolol Beta blocker Bupropion Antidepressant Anxiolytic Sedative Local anaesthetic Sedative Nerve blocker Butanilicaine Local anaesthetic Butaperazine Antipsychotic Butoctamide Serotonin release stimulation Butofilolol Beta blocker Butoxycaine Local anaesthetic Cafedrine Analeptic Calusterone Anabolic Anxiolytic Candesartan Antihypertensive Natural , synthetic Psychotropic cannabinoids and other cannabimimetics Canrenone Diuretic Capsaicin Topical analgesic/irritant Anxiolytic Anticholinergic Carazolol Beta blocker Parasympathomimetic Carbazochrome Haemostatic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Carbetapentane (Pentoxyverine) Antitussive Carbidopa Di hydroxythenylalanine decarboxylase inhibitor Carbimazole Antihyperthyroidism Carbocysteine Mucoactive Sedative Carbuterol Bronchodilator Opioid analgesic Muscle relaxant Carphedon (Phenylpiracetam) Stimulant Carphenazine Antipsychotic Anxiolytic Carteolol Beta blocker Carticaine Local anaesthetic Carvedilol Beta blocker (Norpseudoephedrine) Stimulant Celecoxib Non-steroidal anti-inflammatory drug Celiprolol Beta blocker Cephaeline Emetic betaine Sedative Sedative Chloralbutanol Topical analgesic Anxiolytic Chlormerodrin Diuretic Chlormethiazole Sedative Anxiolytic Sedative Chlorophenesin Muscle relaxant Chlorophenyl piperazine Psychoactive Local anaesthetic Chloroquine Antimalarial Chlorphenoxamine Antipruritic Chlorphentermine Stimulant

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Sedative Antidiabetic Chlorprothixene Antipsychotic Chlorthalidone Diuretic Chlorthenoxazine Non-steroidal anti-inflammatory drug Chlorzoxazone Muscle relaxant Cicloprofen Non-steroidal anti-inflammatory drug Cilazapril Antihypertensive Cilostazol Vasodilator Cimaterol Beta agonist Local anaesthetic Cinchophen Non-steroidal anti-inflammatory drug Antidepressant Clibucaine Local anaesthetic Clidinium Anticholinergic Anxiolytic Clobenzorex Stimulant Clocapramine Antidepressant Clocortolone Corticosteroid Clofenamid Carbonate anhydrase inhibitor Sedative Clomiphene Oestrogen (Clomiprimine) Antidepressant Clomiprimine (Clomipramine) Antidepressant Anxiolytic Clonixin Non-steroidal anti-inflammatory drug Clopamide Dopamine antagonist Cloranolol Beta blocker Anxiolytic Clormecaine Local anaesthetic Clostebol Anabolic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Clothiapine Antidepressant Anxiolytic Anxiolytic Antipsychotic Cocaine Stimulant/local anaethestic Colchicine (Specified Substance) Rheumatic treatment/anti-cancer Conorphone Opioid analgesic Coroxon Anticoagulant Cortivazol Corticosteroid Cotinine metabolite Coumarin Anticoagulant Cropropamide Stimulant Crotehamide Stimulant Cyamemazine Antipsychotic Cyclandelate Vasodilator Sedative Cyclobenzaprine Muscle relaxant Cycloguanil Antimalarial Local anaesthetic Psychoactive Cyclopentolate Antimuscarinic Diuretic Cycrimine Anticholinergic Danazol Anabolic Dapsone Antileprotic Decamethonium Muscle relaxant Dehydrochloromethyltestosterone Anabolic Dehydrochlorotestosterone Anabolic Anxiolytic Demecolcine (Specified Substance) Rheumatic treatment/anti-cancer Anxiolytic Deoxycorticosterone Corticosteroid

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Peptide agonist Deserpidine Antipsychotic Antidepressant Desonide Corticosteroid Desoximethasone (Desoxymethasone) Corticosteroid Desoxyephedrine Stimulant Desoxymethasone (Desoximethasone) Corticosteroid Desoxymethyltestosterone Anabolic Desoxyvinyl-testosterone Anabolic (Addition for 2019) Antitussive Narcotic Opioid analgesic Antitussive Opioid analgesic Diacerein Antiarthritic Diamorphine () Narcotic Diaveridine Folic acid antagonist Muscle relaxant Dibenzepin Psychoactive Dibucaine Local anaesthetic Dichlorisone Corticosteroid Dichlorphenamide Carbonic anhydrase inhibitor Dicumarol Anticoagulant Diethylpropion Anorexic Opioid analgesic Diethyltryptamine Psychedelic Diflorasone acetate Corticosteroid Diflucortolone Corticosteroid Diflunisal Analgesic Digitoxin Anti-arrhythmic Opioid analgesic Dihydrocodeinone Opioid analgesic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Ergot Opioid analgesic Diisopropylamine Vasodilator Dimefline Respiratory stimulant Dimethindene Antipruritic Dimethisoquin Local anaesthetic Dimethylamphetamine Stimulant Dimethyltryptamine Psychedelic Diphenadione Anticoagulant Opioid agonist Opioid analgesic Opioid analgesic Diprophylline Bronchodilator Dipyridamole Antiplatelet Anti-arrhythmic Disulfiram Aldehyde dehydrohenase inhibitor Dixyrazine Antipsychotic Donepezil Cholinesterase inhibitor Dopexamine Beta 2 adrenergic receptor agonist Dothiepin Antidepressant Doxacurium Muscle relaxant Antidepressant Drofenine Antispasmodic Dromostanolone Anabolic Droperidol Antipsychotic Drospirenone Diuretic Drostanolone Anabolic Duloxetine Antidepressant Dyclonine Oral anaesthetic Dyphylline Muscle relaxant Ecgonine methyl ester Cocaine metabolite Efaproxiral Haemoglobin modifier

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Eletriptan Migraine relief Sedative Emepronium Antispasmodic Enciprazine Anxiolytic Endorphins Endogenous Endogenous pain relief Stimulant Epibatidine Analgesic Epi- Anabolic (Addition for 2019) Epiternbolone Anabolic Epitestosterone Anabolic (Addition for 2019) Eplerenone Diuretic (Addition for 2019) Ergonovine (Specified Substance) Vasoconstrictor Ergotamine (Specified Substance) alkaloid Erythrityl tetranitrate Blood vessel relaxant Erythropoietin (EPO), recombinant EPO Erythropoiesis and synthetic analogues Esmolol Beta blocker Anxiolytic Estranediol Anabolic. Threshold substance: Free and conjugated 5alpha-estrane-3beta, 17alpha-diol, 0.045 micrograms per millilitre in urine in male Horse (other than geldings). Etafedrine Adrenergic Etamiphylline Bronchodilator Etamivan Stimulant Etanercept Tumor necrosis factor inhibition Ethacrynic acid Diuretic Ethamivan Respiratory stimulant Ethamsylate Haemostatic Ethaverine Vasodilator Sedative Ethiazide Diuretic Sedative

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Ethinylestradiol Oestrogen Opioid analgesic Ethopropazine Antimuscarinic Anti-epileptic Ethoxzolamide Carbonic anhydrase inhibitor Anxiolytic Ethylamphetamine Stimulant Ethylestrenol Anabolic Ethylisobutrazine Sedative Opioid analgesic Ethylnorepinephrine Bronchodilator Local anaesthetic Anxiolytic Etilefrine Stimulant Anabolic (Addition for 2019) Anxiolytic Etodolac Non-steroidal anti-inflammatory drug Stimulant Sedative Etoricoxib Non-steroidal anti-inflammatory drug Opioid analgesic Exemestane Aromatase inhibitor Famprofazone Stimulant Febaramate Muscle relaxant Anticonvulsant Antihypertensive Fenbufen Non-steroidal anti-inflammatory drug Fenbutrazate Stimulant Fencamfamine Stimulant Fencamine Stimulant Fenclofenac Non-steroidal anti-inflammatory drug

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Fenclozic acid Non-steroidal anti-inflammatory drug Fenethylline (Fenetylline, Phenethylline, Stimulant Phenetylline) Fenetylline (Fenethylline, Phenethylline, Stimulant Phenetylline) Fenfluramine Stimulant Fenoldopam Vasodilator Fenoprofen Non-steroidal anti-inflammatory drug Fenozolone Psychoactive Fenpiprane Gastrointestinal disorders Fenproporex Stimulant Fenspiride Non-steroidal anti-inflammatory drug Opioid analgesic Fentiazac Pain relief Feprazone Non-steroidal anti-inflammatory drug Flavoxate Antispasmodic Anti-arrhythmic Floctafenine Non-steroidal anti-inflammatory drug Flouroprednisolone (Fluprednisolone) Corticosteroid Fluandrenolide (Fluandrenolone, Corticosteroid Fludroxycortide) Fluandrenolone (Fluandrenolide, Corticosteroid Fludroxycortide) Fluanisone Sedative Anxiolytic Fludrocortisone (Fluorocortisone) Corticosteroid Fludroxycortide (Fluandrenolide, Corticosteroid Fluandrenolone) Non-steroidal anti-inflammatory drug Flumethazide Diuretic Antihypertensive Corticosteroid Anxiolytic Fluocinolone Corticosteroid

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Fluocinolone acetonide Corticosteroid Fluocinonide Corticosteroid Fluocortolone Corticosteroid Fluopromazine (Triflupromazine) Antipsychotic Fluoresone Anti-epileptic Fluorocortisone (Fludrocortisone) Corticosteroid Fluorometholone Corticosteroid Fluorophenethylamine Stimulant Fluoroprednisolone Corticosteroid Antidepressant Fluoxymesterone Anabolic Flupenthixol Antidepressant Fluphenazine Antipsychotic Analgesic Fluprednisolone (Flouroprednisolone) Corticosteroid Anxiolytic Flurbiprofen Non-steroidal anti-inflammatory drug Fluspirilene Antipsychotic Anxiolytic Antidepressant Formebolone Anabolic Formestane Aromatase inhibitor Fosinopril Antihypertensive Anticonvulsant Furazabol Anabolic Furazadrol Anabolic (Addition for 2019) Furfenorex Stimulant Galantamine Alzheimer - alkaloid Gallamine Muscle relaxant Gamma amino butyric acid (GABA) Amino acid Gamma-Butyrolactone (GBL) Sedative Gamma-Hydroxybutyrate (GHB) Sedative

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Anxiolytic Gestrinone Anabolic Sedative Growth Factors Growth promotion Growth Hormone (GH) - or analogues Growth promotion Guanabenz Sedative Guanadrel Antihypertensive Guanethidine Antihypertensive Guanoclor Sympatholytic Guanoxan Sympatholytic GW1516 Anabolic Haemaglobin analogues Oxygen transport Halcinonide Corticosteroid Halobetasol Corticosteroid Halodrol Anabolic (Addition for 2019) Neuroleptic Harmaline Psychoactive Heptaminol Stimulant Heroin (Diamorphine) Narcotic Hexafluorenium Muscle relaxant Sedative Hexocyclium Antimuscarinic Local anaesthetic Homatropine Anticholenergic Homophenazine Psychiatric drug Hydralazine Vasodilator; afterload reducer Opioid analgesic Hydroflumethiazide Diuretic Opioid analgesic Opioid analgesic Hydroxyamphetamine Stimulant Hydroxyephedrine (Oxilofrine) Stimulant

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Hydroxygamma amino butyric acid (hydroxy-GABA) Hydroxytestosterone Anabolic Hyoscyamine (Atropine isomer) Anticholenergic Ibandronate Bisphosphonates (Addition for 2019) Psychoactive indole Anti-arrhythmic Iloprost Vasodilator Antidepressant Indapamide Diuretic Indoprofen Non-steroidal anti-inflammatory drug Indoramin Antihypertensive Infliximab Therapeutic antibody Iprindole Antidepressant Iproniazid Antidepressant Anxiolytic Irbesartan Antihypertensive Isoaminile Antitussive Isocarboxazid Antidepressant Isoetharine Beta 2 adrenergic receptor agonist Analgesic Isometheptane Stimulant Isometheptene Sympathomimetic Isoprenaline (Isoprotorenol) Bronchodilator Isopropamide Anticholinergic Isoprotorenol (Isoprenaline) Bronchodilator Isopyrin (Ramifenazone) Pain relief Isosorbide dinitrate Vasodilator Isoxicam Non-steroidal anti-inflammatory drug Kebuzone Non-steroidal anti-inflammatory drug Anxiolytic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Krypton Hypoxia Inducible Factor (HIF) Activator (Addition for 2019) Labetalol Beta blocker Anticonvulsant Lenperone Anxiolytic Leptazole (Pentylenetetrazole) Stimulant Letosteine Mucolytic Letrozole Aromatase inhibitor Levobunolol Beta blocker Levodopa Di hydroxythenylalanine substitute Opioid analgesic Levophacetoperane Boosts brain uptake of catecholamines Opioid analgesic LGD-4033 Anabolic (Addition for 2019) Anti-arrhythmic Lithium Mood stabiliser Respiratory stimulant Opioid analgesic Lofepramine Antidepressant Anxiolytic Anxiolytic Anxiolytic Lornoxicam Non-steroidal anti-inflammatory drug Losartan Antihypertensive Loxapine Antipsychotic Lucanthone Radiation sensitizer Lumiracoxib Non-steroidal anti-inflammatory drug Mabuterol Beta agonist Madol Anabolic (Addition for 2019) Maprotiline Antidepressant Mazindol Anorexic MDA (Methylenedioxyamphetamine) Stimulant

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. MDEA Stimulant (Methylenedioxyethylamphetamine) MDMA Stimulant (Methylenedioxymethamphetamine) Mono-amine oxidase inhibitor Mebeverine Antispasmodic Sedative Mecamylamine Nicotine antagonist Meclofenoxate Stimulant Meconine (Specified Substance) Opioid Anxiolytic Medrysone Corticosteroid Non-steroidal anti-inflammatory drug Mefenorex Stimulant Mefexamide Stimulant Mefruside Diuretic Meldonium Antiischaemia Melperone Antipsychotic Memantine N-methyl D-asparate receptor antagonist Meparfynol Anxiolytic Mepazine Antipsychotic Mepenzolate Muscle relaxant Meperidine () Opioid analgesic Muscle relaxant Mephentermine Stimulant Anticonvulsant Mephobarbital Sedative Mepindolol Beta blocker Meprednisone Corticosteroid (Meprobromate) Anxiolytic Meprobromate (Meprobamate) Anxiolytic Local anaesthetic Opioid analgesic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Meralluride Diuretic Merbaphen Diuretic Mercaptomerin Diuretic Mersalyl Diuretic Mesalamine (Mesalazine) Non-steroidal anti-inflammatory drug Mesalazine (Mesalamine) Non-steroidal anti-inflammatory drug Mesocarb Stimulant Mesoridazine Neuroleptic Mestanolone Anabolic Mesterolone Anabolic Anxiolytic Metaproterenol Bronchodilator Metaraminol Stimulant Muscle relaxant Opioid analgesic Methacholine Hypotensive Methallenestril Oestrogen Stimulant Methandienone Anabolic Methandriol Anabolic Methandrostenolone Anabolic Methantheline Antimuscarinic Sedative Sedative Methasterone Anabolic Methazolamide Diuretic Methcathinone Psychoactive Methenolone Anabolic Methimazole Antihyperthyroidsim Methixene Antispasmodic Sedative Methotrexate Immunomodulator

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Methotrimeprazine Antipsychotic Methoxyphenamine Non-steroidal anti-inflammatory drug Methscopolamine (Methyl ) Muscarinic antagonist Methsuximide Anticonvulsant Methyclothiazide Diuretic Methyl Scopolamine (Methscopolamine) Muscarinic antagonist Methylaminorex Stimulant Methylatropine Anticholinergic Methylchlorthiazide (Methylclothiazide) Diuretic Methylclothiazide (Methylchlorthiazide) Diuretic Methyldienolone Anabolic Methyldihydromorphinone Opioid analgesic Methyldopa Antihypertensive Methylenedioxyamphetamine (MDA) Stimulant Methylenedioxyethylamphetamine Stimulant (MDEA) Methylenedioxymethamphetamine Stimulant (MDMA) Methylephedrine Stimulant Methylergonovine Vasoconstriction Methylhexaneamine Stimulant Methylmethcathinone Psychoactive Methylnortestosterone Anabolic Stimulant Methylprylon () Sedative Methylpseudoephedrine Stimulant Methyltestosterone Anabolic Methyltrienolone Anabolic Methyprylon (Methylprylon) Sedative Methysergide 5-hydroxytryptamine receptor antagonist Meticrane Diuretic Metipranolol Beta blocker

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Metocurine Muscle relaxant Metolazone Diuretic Metoprolol Beta blocker Metrenperone Antipyretic Metyrapone Hydrocortisone synthesis inhibitor Anxiolytic Anti-arrhythmic Psychoactive Antihypertensive Mibolerone Anabolic Midodrine Vasopressor Milrinone Phosphodiesterase 3 inhibitor Vasodilator Mirtazepine Antidepressant Mivacurium Muscle relaxant Modafanil Stimulant Mofebutazone Non-steroidal anti-inflammatory drug Molidustat Hypoxia Inducible Factor (HIF) Activator (Addition for 2019) Molindone Antipsychotic Corticosteroid Montelukast Leucotriene receptor antagonist - treatment

Moperone Antipsychotic Moprolol Beta blocker Morphedrine Stimulant Opioid analgesic Mosapramine Antipsychotic Moxaverine Phosphodiesterase inhibition Muscarine (Specified Substance) Parasympathomimetic Myoinositol tripyrophosphate Pyrophosphate (Addition for 2019) Nabumetone Non-steroidal anti-inflammatory drug

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Nadolol Beta blocker Nadoxolol Anti-arrhythmic Naepaine Local anaesthetic Naftidrofuryl Vasodilator Opioid analgesic Opioid receptor agonist and antagonist Opioid receptor antagonist Nandrolone (Nortestosterone) Anabolic Sympathomimetic Naratriptan 5-hydroxytryptamine agonist (migraine treatment)

Nebivolol Beta blocker Mast cell stabiliser Psychoactive Nefopam Non opioid analgesic Neridronate Bisphosphonates (Addition for 2019) Nialamide Antidepressant Antihypertensive Nicotine Stimulant Nicoumalone Anticoagulant Anti-angina Nifenalol Beta blocker Non-steroidal anti-inflammatory drug Nikethamide Stimulant Non-steroidal anti-inflammatory drug Anxiolytic Antihypertensive Anxiolytic Nomifensine Dopamine re-uptake inhibitor Nonivamide Topical analgesic/irritant Norandrostenediol Anabolic Norandrostenedione Anabolic Norbolethone Anabolic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Norclostebol Anabolic Norcocaine Cocaine metabolite Nordiazepam Tranquiliser Norethandrolone Anabolic Norfenefrine Stimulant Norfenfluramine Stimulant Norfluoxetine Fluoxetine metabolite Normethandrolone Anabolic Norpseudoephedrine (Cathine) Stimulant Nortestosterone (Nandrolone) Anabolic Antidepressant Noscapine Antitussive Nylidrin (Buphenine) Sympathomimetic Octadecafluoronaphthalene Artificial gas carriers in blood (Perfluorodecalin) Octopamine Stimulant Antipsychotic Olmesartan Antihypertensive Olpadronate Bisphosphonates (Addition for 2019) Olsalazine Gut anti-inflammatory Psychoactive Opromazine Orciprenaline Bronchodilator (Specified Substance) Opioid analgesic Osterine Selective Androgen Receptor Modulator Oxabolone Anabolic Oxaflumazine Psychosedative Oxandrolone Anabolic Oxaprozin Non-steroidal anti-inflammatory drug Anxiolytic Anticonvulsant Oxethazaine Topical anaesthetic Oxilofrine (Hydroxyephedrine) Stimulant

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Oxolamine Antitussive Oxprenolol Beta blocker Oxybuprocaine Local anaesthetic Opioid analgesic Oxyguno Anabolic (Addition for 2019) Oxymesterone Anabolic Topical Oxymetholone Anabolic Opioid analgesic Oxypertine Neuroleptic Oxyphencyclimine Antimuscarinic Oxyphenonium Antimuscarinic Paliperidone Antipsychotic Pamidronate Bisphosphonates (Addition for 2019) Palmitoylethanolamid Analgesic (Addition for 2019) Pancuronium Muscle relaxant Papaverine (Specified Substance) - muscle spasm treatment Anticonvulsant Anabolic Paramethasone Corticosteroid Pargyline Mono-amine oxidase inhibitor Antidepressant Pemoline Stimulant Pempidine Ganglionic blocker Penbutolol Beta blocker Penfluridol Antipsychotic Pentaerythritol Tetranitrate Vasodilator Narcotic Pentetrazol Stimulant Pentifylline Vasodilator Sedative Pentoxyverine (Carbetapentane) Antitussive

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Pentylenetetrazole (Leptazole) Stimulant Perfluorocarbons Artificial gas carriers in blood Perfluorodecalin Artificial gas carriers in blood (Octadecafluoronaphthalene) Perfluorooctylbromide Artificial gas carriers in blood Perfluorotripropylamine Artificial gas carriers in blood Periciazine (Pericyazine) Antipsychotic Pericyazine (Periciazine) Antipsychotic Perinodopril Antihypertensive Hypnotic Perphenazine Tranquiliser/phenothiazine derivative Pethidine (Meperidine) Opioid analgesic Anticonvulsant Phenacetin (Acetophenetidin) Analgesic Tranquiliser Opioid analgesic Phenazone Analgesic Phenazopyridine Analgesic Anaesthetic Phendimetrazine Stimulant Psychoactive Phenethylline (Fenethylline, Fenetylline, Stimulant Phenetylline) Phenetylline(Fenethylline, Fenetylline, Stimulant Phenethylline) Central Nervous System Phenindione Anticoagulant Phenmetrazine Stimulant Sedative Phenoxybenzamine Antihypertensive Phenprocoumon Anticoagulant Phenpromethamine Stimulant Muscle relaxant

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Phentermine Anticonvulsant Phentolamine Vasodilator Phenyliprazine Antidepressant Phenylpiracetam (Carphedon) Stimulant Stimulant Antitussive Pholedrine Stimulant Stimulant Opioid analgesic Antipsychotic Anxiolytic Pindolol Beta blocker Pipamazine Anti-emetic/mild tranquiliser Pipamperone Antipsychotic Pipecuronium Muscle relaxant Pipenzolate Antimuscarinic Anxiolytic Methysticum (Kava) Anti-psychotic Piperacetazine Sedative Anticholinergic Piperidolate Anticholinergic Local anaesthetic Piperoxan Adrenergic blocker Pipotiazine Antipsychotic Pipradol (Pipradrol) Stimulant Pipradrol (Pipradol) Stimulant Piquindone Antipsychotic Piracetam Stimulant Diuretic Pirprofen Non-steroidal anti-inflammatory drug Pizotifen Antimigraine Polythiazide Diuretic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Practolol Beta blocker Anabolic (Added for 2019) Anxiolytic Vasodilator Pridinol Muscle relaxant Anticonvulsant Probenecid Diuretic Procarbazine Chemotherapy Procaterol Beta adrenergic receptor agonist Prochlorperazine Antipsychotic Procyclidine Anticholinergic Cholecystokinin antagonist Proguanil Antimalarial Prolintane Stimulant Pronethalol Anti-arrhythmic Anti-arrhythmic Sedative Anaesthetic Proparacaine () Local anaesthetic Tranquiliser Propionylpromazine Tranquiliser Opioid receptor agonist IV anaesthetic Local anaesthetic Propoxyphene Opioid analgesic Stimulant Propyphenazone Non-steroidal anti-inflammatory drug Proquazone Non-steroidal anti-inflammatory drug Prostanozol Anabolic Prothipendyl Antipsychotic Protokylol Sympathomimetic Protriptyline Stimulant antidepressant

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Sedative Proxymetacaine (Proparacaine) Local anaesthetic Proxyphylline Bronchodilator Stimulant Psilocin Psychedelic Pyridostigmine Anticholinesterase Sedative Anti-psychotic Quinalbarbital (Secobarbitone) Sedative Quinbolone Anabolic Quinisocaine Topical anaesthetic Ractopamine Beta agonist RAD140 Anabolic (Addition for 2019) Raloxifene Oestrogen receptor modulator Ramifenazone (Isopyrin) Pain relief Opioid analgesic Reproterol Bronchodilator Reserpine Tranquiliser Rimiterol Bronchodilator Risedronate Bisphosphonates (Addition for 2019) Antipsychotic Ritodrine Tocolytic Rofecoxib Non-steroidal anti-inflammatory drug Local anaesthetic Roxadustat Hypoxia Inducible Factor (HIF) Activator (Addition for 2019) Salicylamide Non-steroidal anti-inflammatory drug SARM LGD-4033 Anabolic (Addition for 2019) SARM YK-11 Anabolic (Addition for 2019) SARM S-4 Anabolic (Addition for 2019) Secobarbitone (Quinalbarbital) Sedative Selegiline Stimulant Antidepressant

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Sibutramine Stimulant Sildenafil Vasodilator (Specified Substance) Anti-arrhythmic Spironolactone Diuretic Stanozolol Anabolic Stenbolone Anabolic Strychnine Muscular convulsions Anticonvulsant Opioid analgesic Sulforidazine Antipsychotic Sulindac Non-steroidal anti-inflammatory drug Sulpiride Antipsychotic Sumatriptan Serotonin agonist - migraine treatment Synephrine (Specified Substance) Stimulant Tamoxifen Oestrogen receptor modulator Tranquiliser Tenoxicam Pain relief Tepoxalin Non-steroidal anti-inflammatory drug Terazocin (Terazosin) Alpha adrenergic blocker Terazosin (Terazocin) Alpha adrenergic blocker Testolactone Aromatase inhibitor Testosterone Anabolic. Threshold substance: 0.02 micrograms free and conjugated testosterone per millilitre in urine from geldings, or 0.055 micrograms free and conjugated testosterone per millilitre in urine from fillies and mares (unless in foal).

Tetrahydrogestrinone (THG) Anabolic (Specified Substance) Opioid alkaloid THG (Tetrahydrogestrinone) Anabolic Thiethylperazine Anti-emetic Thiopropazate Antipsychotic Thioproperazine Cataleptic Antipsychotic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Thiothixene Antipsychotic Thozalinone Psychoactive Thymosin (snythetic fragments) Anabolic Tiaprofenic Acid Non-steroidal anti-inflammatory drug Tibolone Anabolic Timolol Beta blocker Local anaesthetic Tofenacin Antidepressant Non-steroidal anti-inflammatory drug Tolmetin Non-steroidal anti-inflammatory drug Tolvaptan Vaptans (Addition for 2019) Tolycaine Local anaesthetic Torasemide Diuretic Toremifene Oestrogen receptor modulator Analgesic Sympathomimetic Tranylcypromine Mono-amine oxidase inhibitor Antidepressant Trena Anabolic (Addition for 2019) Trenbolone Anabolic Trestolone Anabolic (Addition for 2019) Diuretic Anxiolytic Triflumeprazine Phenothiazene Antipsychotic Trifluoromethylphenyl piperazine Psychoactive Trifluperidol Antipsychotic Triflupromazine (Fluopromazine) Antipsychotic Trihexylphenidyl (Trihexyphenidyl) Acetylcholine inhibitor Trihexyphenidyl (Trihexylphenidyl) Acetylcholine inhibitor Local anaesthetic Trimeprazine Antipruritic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Trimetazidine Angina treatment Antidepressant Tripamide Antihypertensive Stimulant Tulobuterol Bronchodilator Anxiolytic Valdecoxib Pain relief Sedative Anticonvulsant Vardenafil Vasodilator Antidepressant Venom – naturally derived and synthetic Anti-arrhythmic Viloxazine Antidepressant Warfarin Anticoagulant Xipamide Diuretic Xenon Hypoxia Inducible Factor (HIF) Activator (Addition for 2019) Adrenergic Zeranol Oestrogen agonist Zicotinide Analgesic Zilpaterol Beta agonist/repartitioning agent Zimeldine Antidepressant Zoledronate Bisphosphonates (Addition for 2019) Hypnotic Zomepirac Non-steroidal anti-inflammatory drug Hypnotic Zuclopenthixol Antipsychotic

30 November 2018 - Lausanne, Switzerland 2019 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. BANNED METHODS

1. Manipulation of Blood and Blood Components (i.e. Blood Doping, ozone haemotherapy)

 Withdrawal, manipulation and re-infusion of homologous, heterologous, or autologous, blood products or blood cells into the circulatory system with the exception of those performed for lifesaving purposes or the use of veterinary regenerative therapies for the treatment of musculoskeletal injury or disease.

2. Gene Doping

 Any form of genetic modification

30 November 2018 - Lausanne, Switzerland

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