Letter from the Executive Director of Research
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MELBOURNE HEALTH RES EARCH WEEK 2013 Letter from the Executive Director of Research Research Week is one of the highlights of the Melbourne Health calendar. It provides a focus on research where all members of our staff and the community can reflect on the value of research and celebrate the advances in medical science. The week-long program includes an address in the Opening Session by clinician and researcher, Professor Kate Leslie who is the Head of Research in the Department of Anaesthesia and Pain Management. Activities continue with a formal symposium, plenary talks, and interactive research education. Light relief comes in the form of the annual Great Debate. We continue to inform visitors to the hospital with a community engagement booth in the hospital foyer. I would like to thank the Research Week Committee who managed to pull together a wonderful program. Thank you to – Dr Giovanna D’Abaco Ms Carol Jewell Ms Catherine Lander Professor Danny Liew Ms Angela Magira Professor Terry O’Brien Dr Angela Watt In addition, the efforts of those involved in selecting the suitable abstracts and in the adjudication of the Awards and those coordinating and chairing sessions during Research Week are greatly appreciated. Melbourne Health Research Week is successful because of the generous contributions of time, energy and expertise by so many people – thank you. Professor Ingrid Winship Executive Director Research DAY 1 – THURSDAY 23 MAY 2013 Opening Session 1.00 – 2.00 pm, Charles La Trobe Lecture Theatre, Function and Convention Centre, Ground Floor, RMH (Lunch at 12.30 pm) Welcome address: Professor Ingrid Winship, Executive Director of Research, Melbourne Health Key Note Lecture: Professor Kate Leslie, Head of Research, Department of Anaesthesia and Pain Management., “Multi-centre perioperative clinical trials” Plenary Presentation: 1 - Dr Bruce Campbell, “Predicting hemorrhage after thrombolysis using advanced imaging” DAY 2 – FRIDAY 24 MAY 201 3 Research Symposium Concurrent Sessions: 9.15 – 10.15 am , Seminars Room 1 & 2, Function and Convention Centre, Ground Floor (Morning Tea at 10.15 am) Session 1, Seminar Room 1 Session 2, Seminar Room 2 2 Zhen Zeng, Characterization of the 6 Scott Wilson, A novel method to profile the electrophysiological properties of Nav1.1 and cardiovascular stability of dialysis patients by Nav1.2 expressed in HEK293T cell lines continuous measurement using a median hybrid 3 Rejhan Idrizi, Investigating the role of betacellulin preprocessing filter algorithm in the plasma of schizophrenia patients treated 7 Jonathan Goh, Review of optic nerve sheath with the antipsychotic clozapine fenestrations: indications and outcomes 4 Nadia Warner, The dual selection and persistence 8 Sangeetha Ramdave, Association between of an immune escape, drug-resistant, defective CYP2C19 variants and efficacy of Clopidogrel in HBV strain patients after neurointerventional procedures 5 Ping Zheng, Sodium selenate reduces 9 Michael Wong, Characterisation of catheter-tissue neurodegeneration and behavioural impairments contact force during epicardial RF ablation in an in the post-kainic acid status epilepticus rat model ovine model of temporal lobe epilepsy Concurrent Sessions: 10.30 – 11.30 am Session 3, Seminar Room 1 Session 4, Seminar Room 2 10 Sarah Hanieh, The effect of intermittent antenatal 14 Louise Weir, Direct-to-CT model halved RMH iron supplementation on infant outcomes in rural stroke thrombolysis door-to-needle times to 25 Vietnam: a cluster randomised trial minutes in just four months 11 Jacqueline Osborne, Investigating practices relating 15 Vilija Jokubaitis, Predictors of 12-month to malnutrition in Victorian cancer services: results confirmed disability progression after onset of from the point prevalence study clinically isolated syndrome (CIS) suggestive of 12 Natalie Marijanovic, Identifying risk factors for multiple sclerosis hypoglycaemic episodes in hospital inpatients 16 Tomas Kalincik, Relapse incidence in women and 13 Sheena Sullivan, Evidence not shown for waning men throughout the course of multiple sclerosis: of influenza vaccine effectiveness during the 2012 an MSBase cohort study influenza season in Victoria, Australia 17 Aleisha Gorski, Impact of an emergency general surgical service on time to theatre 2 Poster Viewing Session 11.45 am – 12.45 pm, Function and Convention Centre, Ground Floor, RMH (Lunch at 12.00 pm) Melbourne Health Research Week 2013 will display over 130 posters showcasing research in many fields including Infectious Disease, Cancer, Immunology, Nephrology, Cardio-respiratory, Neurosciences, Aged Care, Mental Health, Youth Health, Anaesthesia and Pain Management, Surgery, Emergency, Genetics, Endocrinology, Quality of Care and Medical Imaging. Presenters will be on-hand to discuss their projects. The Great Debate 1:00 – 2:00 pm, Charles La Trobe Lecture Theatre, Function and Convention Centre, Ground Floor, RMH (Lunch at 12.00 pm) “Happy 165th birthday, RMH! You've come a long way...for the better or for worse?” The Royal Melbourne Hospital turned 165 this year but should we be celebrating? Are things better in 2013 compared with the time of the new Melbourne Hospital in 1848? Or could we spare more time with our patients then? Melbourne Health has called together some of the greatest minds of our eminent institution to use their collective intellect to tackle this most challenging issue in the form of a Great Debate. Master of Ceremonies (MC) › Professor Ingrid Winship, Executive Director of Research The proceedings will be presided over by a panel of distinguished judges: › Dr Gareth Goodier, Chief Executive › Ms Christine Fitzerbert, Executive Director of Human Resources › Ms Sharon McGowan, Executive Director Communications and Community Relations › Mr Colin Holland, Executive Director, Finance and Logistics Team for the Affirmative – “Team – For the better” › A/Professor Peter Morley, Director of Medical Education › Ms Sally Campbell, Executive Director Corporate and Information Services › Professor Louis Irving, Head Respiratory and Sleep Disorders Medicine Team for the Negative – “Team – For the worse” › A/Professor Genie Pedagogos, Consultant Nephrologist › Dr Dan Steinfort, Respiratory Physician › Dr Sam Hume, Director of Physician Education and ID Physician 3 DAY 3 – SATURDAY 25 MAY 2013 Surgical Research Forum 8.30 – 9.30 am, Ewing Lecture Theatre, Level 5, Clinical Sciences Building Chaired by Professor Andrew Kaye 18 Rose Shakerian, Does consultant-led care within an acute care surgical unit improve patient outcomes at a level 1 trauma centre? 19 Andrew Nichols, DTI tractography reveals changes in the optic radiations of patients with persistent visual impairment following surgery for optic chiasm compression 20 Chunyan Ma, The role of TGF-β-Smad1/5 signalling in tumour cell endothelialisation 21 Wayne Ng, Murine Orthotopic Bioluminescent Glioma Stem Cell Xenograft Model 22 Jingyi Sheng, TGF-β and autoimmune diseases in human and mice 23 Stanley Stylli, The Tks5 adaptor protein – a regulator of invadopodium function and metastasis in cancer cells DAY 4 – MONDAY 27 MAY 2013 How to Undertake Small Clinical Studies Pt. 1 19.00 am – 12.00 pm, 7 East Seminar Room, Main Building, RMH Study designs and basic epidemiological and statistical concepts This session is coordinated by the Melbourne EpiCentre. Registration is required for this session as there are limited places. To register, please send an email to: [email protected] or telephone 9342 8772. DAY 5 – TUESDAY 28 MAY 2013 How to Undertake Small Clinical Studies Pt. 2 9.00 am – 12.00 pm, I.T. Training Room, Basement, Main Building, RMH Data analysis using Microsoft Excel This session is coordinated by the Melbourne EpiCentre. Registration is required for this session as there are limited places. To register, please send an email to: [email protected] or telephone 9342 8772. 4 DAY 6 – WEDNESDAY 29 MAY 201 3 Allied Health Research Skills 1pm - 3.00 pm, Seminar Room 1, Function and Convention Centre, Ground Floor, RMH Research Skills Workshop The aim of this informal interactive workshop, chaired by Professor Danny Liew, is to guide allied health clinicians who want to build research into their everyday practice. Two case studies will be presented to illustrate how to go about gaining approval for quality assurance applications and formal ethics /research governance applications. A panel of experienced researchers will also share their wisdom and experience on the topic. 3.15pm – 4.30pm, Seminar Room 1, Function and Convention Centre, Ground Floor, RMH Research Symposium The workshop will be followed by a short symposium consisting of three presentations illustrating different approaches to developing and progressing clinical relevant research. This will include a brief background of their research, their progress to date and the lessons they have learnt in the process. DAY 7 – THURSDAY 30 MAY 2013 RMH Academic Research Centre Symposium Genomics Advancing Translational Research 9.00 am – 12.30 pm, Charles La Trobe Lecture Theatre, Function and Convention Centre (Lunch at 12.30 pm) Chair: Professor Patricia Desmond Opening Address: Professor James Angus Key Note Lecture: Dr Gareth Goodier, What it means to be a world leading academic medical centre in the 21st century The opening of the RMH Academic Research Centre Symposium 2013 is followed by a series of presentations from experts in various disciplines with research using genetics in Medicine, Radiology, Obstetrics and Gynaecology, Surgery,