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ARTHREXIN indometacin Consumer Medicine Information What is in this leaflet • swelling of the face, lips, tongue or other Tell your doctor if you currently have an parts of the body infection. This leaflet answers some common questions • rash, itching or hives on the skin ARTHREXIN may hide some of the signs of about ARTHREXIN. It does not contain all If you are allergic to aspirin or NSAID an infection. This may make you think, the available information. It does not take the mistakenly, that you are better or that it is place of talking to your doctor or pharmacist. medicines and use ARTHREXIN, the above symptoms may be severe. less serious than it might be. All medicines have risks and benefits. Your Do not take this medicine if you are Signs of an infection include fever, pain, doctor has weighed the risks of you taking swelling or redness. ARTHREXIN against the benefits they pregnant or intend to become pregnant. If you have not told your doctor about any expect it will have for you. Women considering pregnancy should not use ARTHREXIN unless advised to by their of the above, tell them before you start If you have any concerns about taking this doctor. ARTHREXIN may have a reversible taking ARTHREXIN. medicine, ask your doctor or pharmacist. inhibitory effect on fertility. Taking other medicines Keep this leaflet with the medicine. The safety of this medicine during pregnancy You may need to read it again. Tell your doctor or pharmacist if you are has not been established. taking any other medicines, including any that you get without a prescription from What ARTHREXIN is used for Do not breastfeed if you are taking this medicine. your pharmacy, supermarket or health ARTHREXIN contains the active ingredient, The active ingredient in ARTHREXIN food shop. indometacin. It belongs to a group of passes into breast milk and there is a Some medicines and ARTHREXIN may medicines called Non-Steroidal Anti- possibility that your baby may be affected. interfere with each other. These include: Inflammatory Drugs (NSAIDs). Do not take ARTHREXIN if: • aspirin, salicylates or other NSAID ARTHREXIN is used to relieve pain and • you have an active peptic ulcer (i.e. a medicines (e.g. ibuprofen) reduce inflammation (swelling, redness and stomach or duodenal ulcer) or have had • anticoagulants such as warfarin, a soreness) that may occur in the following peptic ulcers more than once before medicine used to prevent blood clots conditions: • you have severe heart failure • digoxin, a medicine used to treat heart • different types of arthritis including • you have recently had heart bypass failure or irregular heart beats rheumatoid arthritis, osteoarthritis, gouty surgery arthritis, ankylosing spondylitis and • lithium, a medicine used to treat mood degenerative joint disease of the hip • you have severe liver failure swings and some types of depression • gout • you experience asthma attacks, hives or • probenecid, a medicine used to treat gout rash or itching of the nose, throat or eyes • muscle and bone injuries such as sprains, • diuretics, also known as fluid or water with aspirin or other NSAIDs strains, low back pain (lumbago) and tablets tendonitis, such as tennis elbow • you are vomiting blood or material that • some medicines used to treat high blood looks like coffee grounds • pain and swelling after setting broken or pressure or heart conditions, including dislocated bones • you are bleeding from the back passage, ACE inhibitors or betablockers or have black sticky bowel motions or medicines used in combination with a • menstrual cramps (period pain) bloody diarrhoea thiazide diuretic Although ARTHREXIN can relieve the Do not take this medicine after the expiry • decongestants symptoms of pain and inflammation, it will date printed on the pack has passed or if not cure your condition. • ciclosporin, a medicine used to prevent the packaging is torn or shows signs of organ transplant rejection or suppress the Ask your doctor if you have any questions tampering. immune system about why this medicine has been If it has expired or is damaged, return it to • methotrexate, a medicine used to treat prescribed for you. your pharmacist for disposal. Your doctor may have prescribed it for arthritis and certain types of cancers If you are not sure whether you should another reason. These medicines may be affected by start taking this medicine, talk to your This medicine is not addictive. ARTHREXIN or may affect how well it doctor. works. You may need different amounts of It is available only with a doctor's Before you start to take it your medicines or you may need to take prescription. Tell your doctor if you have allergies to different medicines. There is not enough information to any other medicines, including aspirin and Your doctor and pharmacist have more recommend the use of this medicine for other NSAID medicines, foods, dyes or information on medicines to be careful with children under the age of 2 years preservatives. or avoid while taking ARTHREXIN. Before you take ARTHREXIN Tell your doctor if you have, or have had, Use in the elderly any of the following medical conditions: Elderly patients may be more sensitive to the When you must not take it • stomach ulcers or other stomach effects or side effects of this medicine. Do not take ARTHREXIN if you have an problems allergy to: • heartburn or indigestion How to take ARTHREXIN • any medicine containing indometacin • bowel or intestinal problems such as Follow all directions given to you by your • aspirin or any other NSAID medicines ulcerative colitis doctor and pharmacist carefully. • any of the ingredients listed at the end of • kidney or liver disease They may differ from the information contained in this leaflet. this leaflet • diabetes If you do not understand the instructions Many medicines used to treat headache, • high blood pressure or heart disease period pain and other aches and pains contain on the box/bottle, ask your doctor or • history of chest pain (angina), heart pharmacist for help. aspirin or other NSAID medicines. problems or stroke How much to take If you are not sure if you are taking any of • history of swelling in the feet or ankles these medicines, ask your doctor or Your doctor will tell you how many capsules pharmacist. • a tendency to bleed or other blood you need to take each day. The dose will problems Some of the symptoms of an allergic reaction depend on the condition being treated and may include: • psychiatric problems your response to the treatment. Your initial • shortness of breath • seizures or fits (epilepsy) dose will be maintained or adjusted until a satisfactory response is noted. • wheezing or difficulty breathing • Parkinson's disease • asthma • eye disease ARTHREXIN Published by MIMS July 2021 1 The dose varies from patient to patient. The While you are taking ARTHREXIN Do not be alarmed by the following list of usual dose is between 50 mg and 200 mg per side effects. day, given in divided doses. Things you must do You may not experience any of them. Elderly patients may need smaller doses. If you are about to be started on any new Ask your doctor or pharmacist to answer Tell your doctor of any changes in your medicine, remind your doctor and any questions you may have. condition, as you may require a change in pharmacist that you are taking Tell your doctor or pharmacist if you the dose of ARTHREXIN. ARTHREXIN. notice any of the following and they worry The dose for menstrual cramps (period pain) Tell any other doctors, dentists and you: is usually one 25 mg capsule every eight pharmacists who treat you that you are • stomach upset or pain including nausea hours, starting with the onset of bleeding or taking this medicine. (feeling sick), vomiting, cramps, loss of cramps. If you are going to have surgery, tell the appetite How to take it surgeon or anaesthetist that you are • heartburn or indigestion (possible taking this medicine. symptoms of an ulcer in the tube that Swallow the capsules whole with a full ARTHREXIN may cause prolonged bleeding glass of water. carries food from the throat to the and may need to be stopped before surgery. stomach) ARTHREXIN may also be taken with food, If you become pregnant while taking this Some of the stomach upset, such as nausea milk or an antacid, if advised by your doctor medicine, tell your doctor immediately. or pharmacist. and heartburn, may be reduced by taking the Tell your doctor if you get an infection capsules with food or an antacid, if advised This may help reduce the possibility of while taking ARTHREXIN. by your doctor or pharmacist. stomach and bowel problems. ARTHREXIN may hide some of the signs of • constipation, diarrhoea When to take it an infection and may make you think, mistakenly, that you are better or that it is • hearing disturbances such as buzzing or Take ARTHREXIN with or immediately ringing in the ears after food. less serious than it might be. • headache, dizziness, light-headedness How long to take it Signs of an infection include fever, pain, swelling or redness. may occur in the first few days of Continue taking your medicine for as long treatment. If this worries you or as your doctor tells you to. If you are about to have any blood tests, continues, contact your doctor tell your doctor that you are taking this Depending on your condition, you may need medicine. • tiredness this medicine for a few days, a few weeks or • change in mood such as depression, for longer periods. Keep all of your doctor's appointments so that your progress can be checked. anxiety or irritability As with other NSAID medicines, if you are ARTHREXIN can increase blood pressure in These are the more common side effects of using ARTHREXIN for arthritis, it will not some people, so your doctor will want to ARTHREXIN.