Feb/Mar, 2021 SMART PAGES SINCE 2006 DBUSINESSETR - POLITICS OI- COMMUNITYT “Building Business to Business and Business to Community Relationships” INSIDE THIS ISSUE EXCLUSIVE Anthony Adams Why I want to be Everyone’s Mayor in Detroit pg. 11 Kizzmekia Corbett Lead Scientific Researcher, Coronavirus Vaccine pg. 4 www.detroitsmartpages.com | [email protected] Commonly asked questions about COVID-19 VACCINES 1. What are the differences and second time, it really develops that (LNP) carrier, essential for efficient vaccine at an alternate site. similarities between the Moderna full, long term memory. delivery of the mRNA, were FDA If you have ever had a severe and Pfizer vaccines? 4. What are the common side approved only a couple years ago. reaction to the Pfizer or Moderna • Both vaccines are about 95% ef- effects of the vaccine? Additional vaccines for rabies, Zika COVID-19 vaccines, or any of their fective. Pfizer and Moderna had a The most common side effects and influenza remain under devel- components, you cannot receive fair and comparable spread of races that have been reported with the opment and it is likely we will see the vaccine. and ethnicities included in the clin- COVID-19 vaccine include: other mRNA vaccines approved in • If you have had an anaphylactic ical trials. There does not appear • Injection site pain the near future. reaction to any vaccine or in- to be any significant differences in • Tiredness 8. Will this be a once a year vaccine jectable, you cannot receive the vaccine effectiveness between the • Headache or once you have both doses will it COVID-19 vaccine at Beaumont at two brands. • Muscle pain be for life? this time without an approval/eval- • For the Pfizer vaccine, the first • Chills We don’t yet know how long the uation from an allergist. However, and second dose should be approx- • Joint pain protection from the vaccine will you can be evaluated by an allergist imately 21 days apart and is recom- • Fever last. Once more data is available, or immunologist to see if you can mended for ages 16 and up. • Injection site swelling we will be able to determine how safely receive the vaccine at an • For the Moderna vaccine, the first • Injection site redness frequently we will need booster alternate clinic. and second dose should be approx- • Nausea vaccine doses. The vaccine appointment may imately 28 days apart and is recom- • Feeling unwell be scheduled after your allergist mended for ages 18 and up. • Swollen lymph nodes 9. How long after administration of approves if you meet the state’s • Both vaccines have the same side 5. What are the side effects of the the second dose of the vaccine can distribution criteria. Please bring effects listed with the CDC. The second dose? we consider it to be fully effective? your allergist’s written approval to most common side effects include Based on the study data, some Protection begins building soon af- the vaccine appointment. tiredness, headache and chills. individuals may have somewhat in- ter the first dose, and studies sug- • If you have had any other kind • Pfizer’s vaccine must be kept at creased symptoms with the second gest maximum protection begins of anaphylactic reaction, such as much lower temperatures than the dose compared with the first. These about 7 to 14 days after the second to food or the environment, you Moderna vaccine. symptoms should still be manage- dose. can receive the vaccine at one of 2. How do COVID-19 mRNA able with simple over-the-counter 10. Do I need to continue wearing our vaccine clinics if you meet the vaccines work? interventions such as ibuprofen. a mask and social distancing after state’s distribution criteria. Howev- mRNA, or messenger RNA, is ge- 6. What if you’re asymptomatic I receive both doses of the vaccine? er, you will be asked to remain in netic material that contains in- and don’t know you’re COVID-19 It’s important for everyone to observation for 30 minutes instead structions for making proteins. positive and you receive the vac- continue using all the tools avail- of 15 minutes. mRNA vaccines for COVID-19 cine? What will happen? able to us to help stop this pandem- 12. I have had allergic reactions to contain synthetic mRNA. Inside CDC is recommending even those ic, like covering your mouth and vaccines in the past. Should I get the body, the mRNA enters human who have had COVID-19 and have nose with a mask, washing hands Moderna or Pfizer? cells and instructs them to produce antibodies receive the vaccine, so often, and staying at least 6 feet Severe allergic reactions from the “spike” protein found on the this is not a problem. However, we away from others. Experts need to either vaccine are very low risk and surface of SARS-CoV-2, the virus ask you wait 90 days after the first understand more about the pro- there shouldn’t need to be a prefer- that causes COVID-19. The body onset of symptoms to schedule tection that COVID-19 vaccines ence for one over the other due to recognizes the spike protein as an your first vaccination. provide before deciding to change allergies. According to the CDC, invader, and produces antibodies 7. I understand that the COVID-19 those recommendations. most of all severe allergic reactions against it. If the antibodies later en- vaccine is the first mRNA approved 11. If someone is vaccinated can occur within 15 minutes of vacci- counter the actual virus, they are vaccine in the U.S., but that they they still be a carrier of COVID-19 nation, which is when patients are ready to recognize and destroy it have been researching MRNA vac- and bring it into their household? in the observation area of the vac- before it causes illness. cines for decades. I would like to We are hopeful that vaccinated in- cine clinics. Allergic reactions to 3. Why did I need to get two doses get vaccinated, but I would like dividuals will be less likely to carry food or environmental causes are of the vaccine? What happens if I to know first why none of the oth- the virus that causes COVID-19; not a factor in getting vaccinated don’t get my second shot? er MRNA vaccines have been ap- however, additional studies are for COVID-19. There are some viruses and bacte- proved, but this one has. needed to confirm. 13. Can I choose which type of ria that we vaccinate against that We are fortunate that recent ad- What if I have allergies or have had vaccine I want when I make my one dose of the vaccine just doesn’t vances over the past few years an allergic reaction to a appointment? provide full immunity in order to allowed this technology to be vaccine in the past? The number and type of vac- prevent illness if you were to be immediately utilized to rapidly Thanks to new information, cines receives vary week to week, exposed to it, whereas priming the develop COVID-19 vaccines with Beaumont re-vamped the process depending on what the State of system allows your immune sys- very promising efficacy results for determining who can safely be Michigan sends. Therefore, you are tem to react to it once, create some without compromising safety. For vaccinated at one of our vaccine not able to select the type of vaccine memory and, when exposed to it a example, the lipid nanoparticle clinics, and who should receive the you receive when scheduling. www.detroitsmartpages.com FEBRUARY/MARCH 2021 | PAGE 2 W A Y N E C O U N T Y S E N I O R S Kizzmekia Corbett-Lead Scientist, Vaccine Research Center (VRC), Coronavirus Virus Kizzmekia “Kizzy” Shanta Cor- called Proj- viral immunologist, at the NIH. Her that messenger RNA (mRNA) encod- bett an American viral immunolo- ectSEED, research aims to uncover mecha- ing S protein could be used to excite gist at the Vaccine Research Center spent her nisms of viral pathogenesis and host the immune response to produce (VRC) at the National Institute of Al- summer immunity. She specifically focuses protective antibodies against corona- lergy and Infectious Diseases, Nation- holiday on development of novel vaccines virus disease 2019. To manufacture al Institutes of Health (NIAID NIH) working in for coronaviridae. Her early research and test the COVID-19 vaccine Cor- based in Bethesda, Maryland. Ap- research considered the development of Severe bett’s team partnered with Moderna, pointed to the VRC in 2014, she is cur- laborato- Acute Respiratory Syndrome (SARS) a biotechnology company, to rapidly rently the scientific lead of the VRC’s ries, one of and Middle East Respiratory Syn- enter animal studies. Subsequent- Coronavirus Team, with research ef- which was drome (MERS) vaccine anti- ly, the vaccine entered Phase 1 clin- forts aimed at propelling novel corona- at UNC’s gens. During this time, she identified ical trial only 66 days after the virus virus vaccines, including a COVID-19 Kenan Labs a simple way to make spike proteins sequence was released. The trial, vaccine. In December 2020, the Insti- with organic chemist James Mor- that are stabilized in a conformation to be completed in at least 45 peo- tute’s Director Anthony Fauci said: kin. In 2005, she was a summer intern that renders them more immunogenic ple, is a dose escalation study in the “Kizzy is an African American sci- at Stony Brook University in Gloria and manufacturable, in collaboration form of two injections separated by entist who is right at the forefront Viboud’s lab where she studied Yersin- with researchers at Scripps Research 28 days.