With Schizophrenia and Bipolar Disorders Profiles in Samples From
Human Endogenous Retrovirus Expression Profiles in Samples from Brains of Patients with Schizophrenia and Bipolar Disorders Oliver Frank, Michelle Giehl, Chun Zheng, Rüdiger Hehlmann, Christine Leib-Mösch and Wolfgang Seifarth J. Virol. 2005, 79(17):10890. DOI: Downloaded from 10.1128/JVI.79.17.10890-10901.2005. Updated information and services can be found at: http://jvi.asm.org/content/79/17/10890 http://jvi.asm.org/ These include: REFERENCES This article cites 58 articles, 18 of which can be accessed free at: http://jvi.asm.org/content/79/17/10890#ref-list-1 on September 17, 2013 by GSF Forschungszentrum F CONTENT ALERTS Receive: RSS Feeds, eTOCs, free email alerts (when new articles cite this article), more» Information about commercial reprint orders: http://journals.asm.org/site/misc/reprints.xhtml To subscribe to to another ASM Journal go to: http://journals.asm.org/site/subscriptions/ JOURNAL OF VIROLOGY, Sept. 2005, p. 10890–10901 Vol. 79, No. 17 0022-538X/05/$08.00ϩ0 doi:10.1128/JVI.79.17.10890–10901.2005 Copyright © 2005, American Society for Microbiology. All Rights Reserved. Human Endogenous Retrovirus Expression Profiles in Samples from Brains of Patients with Schizophrenia and Bipolar Disorders Oliver Frank,1* Michelle Giehl,1 Chun Zheng,1 Ru¨diger Hehlmann,1 Christine Leib-Mo¨sch,1,2 and Wolfgang Seifarth1 Medical Clinic III, Faculty of Clinical Medicine Mannheim, University of Heidelberg, D-68305 Mannheim, Germany,1 Downloaded from and GSF Research Center for Environment and Health, Institute of Molecular Virology, D-85764 Oberschleissheim, Germany2 Received 9 March 2005/Accepted 20 May 2005 The detection and identification of retroviral transcripts in brain samples, cerebrospinal fluid, and plasma of individuals with recent-onset schizophrenia and schizoaffective disorders suggest that activation or upregu- lation of distinct human endogenous retroviruses (HERVs) may play a role in the etiopathogenesis of neuro- psychiatric diseases.
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