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888.267.4436 [email protected] www.origene.com Name: Catalog: CF504201 Product Data Sheet - CARRIERFREE

Components: • (CF504201)

Amount: 100ug

Immunogen: Full length human recombinant protein of human ACD(NP_001075955) produced in HEK293T cell.

Host: Mouse

Isotype: IgG2b

Species Reactivity: Human

Guaranteed Applications:

Suggested WB 1:2000, IF 1:100, Dilutions:

Buffer: PBS (pH7.3), 8% Trehalose

Purification: Purified from mouse ascites fluids by affinity chromatography

Storage Condition: Shipped at room temperature. Upon delivery store at -20C. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.

Reconstitution: Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)

Target

Target Name: Homo sapiens adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 1

Alternative Name: PIP1; PTOP; TINT1; TPP1

Database Link: NP_001075955

Function: This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. © 2015 OriGene Technologies, Inc. 9620 Medical Center Dr., Suite 200, Rockville, MD 20850 tripeptidyl-peptidase I. [provided by RefSeq].