DOCSLIB.ORG

Big Data in Biology and Medicine

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Big Data in Biology and Medicine FOruM Big Data in Biology and Medicine Based on material from a joint workshop with representatives of the international Data-Enabled Life Science Alliance, July 4, 2013, Moscow, Russia O. P. Trifonova1*, V. A. Il’in2,3, E. V. Kolker4,5, A. V. Lisitsa1 1 Orekhovich Research Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Pogodinskaya Str. 10, Bld. 8, Moscow, Russia, 119121 2 Scientific Research Center “Kurchatov Institute,” Academician Kurchatov Sq. 1, Moscow, Russia 123182 3 Skobel’tsyn Research Institute of Nuclear Physics, Lomonosov Moscow State University, Leninskie Gory 1, Bld. 58, Moscow, Russia, 119992 4 DELSA Global, USA 5 Seattle Children’s Research Institute, 1900 9th Ave Seattle, WA 98101, USA *E-mail: [email protected] he task of extracting new dealing with the analysis of large Big Data world: either molecular knowledge from large data experimental data sets and com- biology in the “omics” format, or in- tsets is designated by the mercial companies developing in- tegrative biology in brain modeling, term “Big Data.” to put it simply, formation systems. the workshop or social sciences? the Big Data phenomenon is when participants delivered 16 short re- the tasks of working with large the results of your experiments can- ports that were aimed at discussing data sets can be subdivided into two not be imported into an excel file. how manipulating large data sets groups: (1) when data are obtained estimated, the volume of twitter is related to the issues of medicine interactively and need to be proc- chats throughout a year is several and health care. essed immediately and (2) when orders of magnitude larger than the workshop was opened by there is a large body of accumulat- the volume of a person’s memory Prof. eugene Kolker, who pre- ed data requiring comprehensive accumulated during his/her entire sented a report on the behalf of interpretation. the former category life. As compared to twitter, all the the Data-enabled Life Science of data is related to commercial sys- data on human genomes constitute Alliance (DeLSA, www.delsaglo- tems, such as Google, twitter, and a negligibly small amount [1]. the bal.org). the alliance supports the Facebook. repositories of genomic problem of converting data sets into globalization of bioinformatics ap- and proteomic data exemplify the knowledge brought up by the u.S. proaches in life sciences and the latter type of data. national Institutes of Health in 2013 establishment of scientific commu- Systems for handling large data is the primary area of interest of the nities in the field of “omics.” the arrays are being developed at the Data-enabled Life Science Alliance main idea is to accelerate transla- Institute for System Programming, (DeLSA, www.delsaglobal.org) [2]. tion of the results of biomedical re- russian Academy of Sciences, with Why have the issues of compu- search to satisfy the needs of the special attention on poorly struc- ter-aided collection of Big Data cre- community. tured and ambiguous data that are ated incentives for the formation Large data sets that need to be typical of the medical and biological of the DeLSA community, which stored, processed, and analyzed fields. collections of software utili- includes over 80 world-leading re- are accumulated in many scientific ties and packages, as well as dis- searchers focused on the areas of fields, in addition to biology; there tributed programming frameworks medicine, health care, and applied is nothing surprising about this fact. running on clusters consisting of information science? this new Large data sets in the field of high- several hundreds and thousands of trend was discussed by the partici- energy physics imply several dozen nodes, are employed to implement pants of the workshop “convergent petabytes; in biology, this number is smart methods for data search, technologies: Big Data in Biology lower by an order of magnitude, al- storage, and analysis. Such projects and Medicine.” though it also approaches petabyte as Hadoop (http://hadoop.apache. the total number of workshop scale. the question discussed dur- org/), Data-Intensive computing, participants was 35, including rep- ing the workshop was what russian and noSQL are used to run search- resentatives of research institutes researchers should focus on in the es and context mechanisms when VOL. 5 № 3 (18) 2013 | ActA nAturAe | 13 FOruM From problem to solution: the experts in the field of data processing, Data-Enabled Life Science Alliance-DELSA, are ready to beat back challenge of NIH handling data sets on a number of the analysis of the resulting data derived using genome, transcrip- modern web sites. will become the highest priority. tome and/or proteome profiling Prof. Konstantin Anokhin (Sci- extraction and interpretation techniques; composite, integrative entific research center “Kur- of information from existing data- measures may be used to quantify chatov Institute”), talked on the bases using novel analytical algo- the distance that separate any two fundamentally novel discipline of rithms will play a key role in science samples. However, as each human connectomics, which is focused on in future. the existence of a large organism has both individual genet- handling data sets by integrating number of open information sourc- ic predispositions and a history of data obtained at various organiza- es, including various databases and environmentalal exposure, the tra- tional levels. Large bodies of data search systems, often impedes the ditional concept of averaged norm will accumulate in the field of neu- search for the desired data. Accord- would not be appropriate for per- roscience because of the merging ing to Andrey Lisitsa (research In- sonalized medicine applications in of two fundamental factors. First, stitute of Biomedical chemistry, its true sense. Instead, Prof. Ancha an enormous amount of results ob- russian Academy of Medical Sci- Baranova introduced the concept of tained using high-resolution ana- ences), existing interactomics data- a multidimensional space occupied lytical methods has been accumu- bases coincide to no more than 55% by set of normal sample tissue and lated in the field of neurosciences. [3]. the goal in handling large data the tissue-specific centers within Second, the main concern of scien- sets is to obtain a noncontradictory this space (“the ideal state of the tists is whole-brain functioning and picture when integrating data tak- tissue”). the diseased tissues will be how its function is projected onto en from different sources. located at a greater distance from the system (mind, thought, action), the concept of dynamic profiling the center as compared to healthy rather than the function of individ- of a person’s health or the state of ones. the proposed approach allows ual synapses. Obtaining data on the an underlying chronic disease us- one to abandon binary (yes/no) pre- functioning of the brain as a system ing entire sets of high throughput dictions and to show the departure includes visualization techniques: data without reducing the dataset of a given tissue sample as a point in high-resolution computed tomog- to the size of the diagnostic biomar- an easily understandable line graph raphy, light microscopy, and elec- ker panels is being developed at the that places each sample in the con- tron microscopy. Megaprojects on research center of Medical Ge- text of other samples collected from brain simulation have already been netics of the russian Academy of patients with the same condition launched (e.g., the Human Brain Medical Sciences. the description and associated with survival and Project in europe); the investments of a normal human tissue requires other post-hoc measures. to obtaining new experimental data one to integrate several thousand Prof. Vsevolod Makeev (Institute will be devalued with time, while quantifiable variables that may be of General Genetics, russian Acad- 14 | ActA nAturAe | VOL. 5 № 3 (18) 2013 FOruM emy of Sciences) asserted in his re- Medical data need to be proc- Watson supercomputer in various port that we will be dealing with essed interactively so that a pre- contexts. this supercomputer was large data sets more frequently in liminary diagnosis can be made no designed by IBM to provide an- the near future. there will be two later than several minutes after swers to questions (theoretically types of data: data pertaining to the the data have been obtained. the any questions!) formulated using individual genome (the 1000 Ge- “Progress” company is currently the natural language. It is one of nomes Project), which are obtained developing a system for remote the first examples of expert sys- once and subsequently stored in monitoring of medical indicators tems utilizing the Big Data princi- databases to be downloaded when using mobile devices and the cel- ple. In 2011, it was announced that required. the second type of data lular network for data transfer the supercomputer will be used to pertains to the transcriptome or (telehealth, report by Oleg Gash- process poorly structured data sets proteome analysis, which is con- nikov). this method allows one to in order to solve medical and health ducted on a regular basis in order provide 24-hour out-of-hospital care problems [7]. to obtain an integrative personal monitoring of a patient, which is When analyzing the problem of omics profile [4]. there are several supposed to reduce medical serv- Big Data in biology and medicine, providers of such data in the case of ices costs in future. At this stage, one should note that the disciplines genomes; russian laboratories can techniques for forming alarm pat- have been characterized by the ac- use these repositories and employ terns are to be developed based on cumulation of large data sets that their own bioinformatics approach- accumulated data; algorithms are describe the results of observations es to arrive at new results [5].
Load more

Recommended publications
  • Intel Capital Leads Usd 38 Million Investment in Russian Ecommerce Business Kupivip
    INTEL CAPITAL LEADS USD 38 MILLION INVESTMENT IN RUSSIAN ECOMMERCE BUSINESS KUPIVIP Intel Capital invests in KupiVIP, one of Russia’s most recognizable fashion ecommerce brands, adding to its consumer Internet footprint in the country RUSSIA, June 21, 2012 – Intel Capital, Intel’s global investment and M&A organisation, today announced it has led a $38 million investment round in Moscow-based KupiVIP Holding, an operator of popular Russian fashion ecommerce websites. Acton Capital Partners and the European Bank of Reconstruction and Development joined the financing round along with existing investors Accel and Balderton. KupiVIP will use the investment to support further development of its ecommerce platforms and the scaling of operations. “Fashion ecommerce sites, customized to local cultural preferences and technology usage models, are major drivers of entrepreneurship and economic growth worldwide,” said Arvind Sodhani, President of Intel Capital and Executive Vice President of Intel. “With investments in similar sites from China to Brazil, Intel Capital brings significant experience from working with these types of businesses all over the world and we look forward to applying our expertise and global network to help KupiVIP take advantage of the great opportunities the Russian market has to offer.” Christian Morales, Vice President, Intel and General Manager of Intel Europe, Middle East and Africa added: “Ecommerce is growing very fast in Russia and we are very pleased to be contributing to it by investing in KupiVIP and bringing in our best technology to improve the customer’s experience”. Founded by Oskar Hartmann, KupiVIP Holding is the largest fashion ecommerce company in Russia, attracting more than 500,000 customers to its websites each day.
    [Show full text]
  • Utilizing Context for Novel Point of Interest Recommendation by Jason
    Utilizing Context for Novel Point of Interest Recommendation by Jason Matthew Morawski A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Software Engineering and Intelligent Systems Department of Electrical and Computer Engineering University of Alberta © Jason Matthew Morawski, 2017 ii Abstract Recommender systems are a modern solution for suggesting new items to users. One of their uses is for novel point of interest recommendation, recommending locations to a user which they have not visited. This can be applied to a location-based social network, which contains information about their users' travel history and social connections. Within this context, there are various challenges, such as data sparsity, that limit recommendation effectiveness. We propose an algorithm for personalized novel point of interest recommendation to overcome these challenges. Our solution leverages social, temporal, and spatial context, together with collaborative filtering and a classification algorithm. iii Preface Chapter 3 of this thesis has been submitted to ACM Transactions on Interactive Intelligent Systems as Jason Morawski, Torin Stepan, Scott Dick and James Miller, 2017. Novel Point of Interest Recommendation with Location-Based Social Networks. Portions of chapters 1 and 2 were also present it that paper. For the paper, I have conducted all of the research and experimentation. The contributions of Torin Stepan relate to his initial development of experimentation software which the current work has expanded upon. My supervisors, Scott Dick and James Miller provided editorial feedback and guidance for this work. iv Acknowledgements I would like to thank my supervisors, Scott Dick and James Miller for their efforts in guiding me through my graduate program.
    [Show full text]
  • Spot: Representing the Social, Spatial, and Temporal Dimensions of Human Mobility with A
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by IMT Institutional Repository #07 2013 IMT LUCCA CSA TECHNICAL REPORT SERIES 07 May 2013 RA Computer Science and Applications SPoT: Representing the Social, Spatial, and Temporal Dimensions of Human Mobility with a Unifying Framework Dmytro Karamshuk Chiara Boldrini Marco Conti Andrea Passarella IMT LUCCA CSA TECHNICAL REPORT SERIES #07/2013 © IMT Institute for Advanced Studies Lucca Piazza San Ponziano 6, 55100 Lucca Research Area Computer Science and Applications SPoT: Representing the Social, Spatial, and Temporal Dimensions of Human Mobility with a Unifying Framework Dmytro Karamshuk IMT Institute for Advanced Studies Lucca Chiara Boldrini IIT-CNR, Pisa Marco Conti IIT-CNR, Pisa Andrea Passarella IIT-CNR, Pisa SPoT: Representing the Social, Spatial, and Temporal Dimensions of Human Mobility with a Unifying Framework Dmytro Karamshuk, Chiara Boldrini, Marco Conti, Andrea Passarella IIT-CNR, Pisa, Italy Abstract Modeling human mobility is crucial in the analysis and simulation of oppor- tunistic networks, where contacts are exploited as opportunities for peer-to- peer message forwarding. The current approach with human mobility mod- eling has been based on continuously modifying models, trying to embed in them the mobility properties (e.g., visiting patterns to locations or specific distributions of inter-contact times) as they came up from trace analysis. As a consequence, with these models it is difficult, if not impossible, to modify the features of mobility or to control the exact shape of mobility metrics (e.g., modifying the distribution of inter-contact times). For these reasons, in this paper we propose a mobility framework rather than a mobility model, with the explicit goal of providing a flexible and controllable tool for model- ing mathematically and generating simulatively different possible features of human mobility.
    [Show full text]
  • Belarusian Institute for Strategic Studies Website of the Expert Community of Belarus «Nashe Mnenie» (Our Opinion)
    1 BELARUSIAN INSTITUTE FOR STRATEGIC STUDIES WEBSITE OF THE EXPERT COMMUNITY OF BELARUS «NASHE MNENIE» (OUR OPINION) BELARUSIAN YEARBOOK 2010 A survey and analysis of developments in the Republic of Belarus in 2010 Minsk, 2011 2 BELARUSIAN YEARBOOK 2010 Compiled and edited by: Anatoly Pankovsky, Valeria Kostyugova Prepress by Stefani Kalinowskaya English version translated by Mark Bence, Volha Hapeyeva, Andrey Kuznetsov, Vladimir Kuznetsov, Tatsiana Tulush English version edited by Max Nuijens Scientific reviewers and consultants: Miroslav Kollar, Institute for Public Affairs, Program Director of the Slovak annual Global Report; Vitaly Silitsky, Belarusian Institute for Strategic Studies (BISS, Lithuania); Pavel Daneiko, Belarusian Economic Research and Outreach Center (BEROC); Andrey Vardomatsky, NOVAK laboratory; Pyotr Martsev, BISS Board member; Ales Ancipenka, Belaru- sian Collegium; Vladimir Dunaev, Agency of Policy Expertise; Viktor Chernov, independent expert. The yearbook is published with support of The German Marshall Fund of the United States The opinions expressed are those of the authors, and do not necessari- ly represent the opinion of the editorial board. © Belarusian Institute for Strategic ISSN 18224091 Studies 3 CONTENTS EDITORIAL FOREWORD 7 STATE AUTHORITY Pyotr Valuev Presidential Administration and Security Agencies: Before and after the presidential election 10 Inna Romashevskaya Five Hundred-Dollar Government 19 Alexandr Alessin, Andrey Volodkin Cooperation in Arms: Building up new upon old 27 Andrey Kazakevich
    [Show full text]
  • Intel Capital Invests in Russian Companies Altergeo and Sapato
    Intel Capital Invests in Russian Companies AlterGeo and Sapato RUSSIA, June 9th, 2011- Intel Capital, Intel Corporation’s global investment organization, has today announced two new investments in Russian companies as part of its ongoing commitment to support technological innovation in the country. Intel Capital announced it has led a round of investment in AlterGeo, geo-location social networks in Russia with underlined location identification technology. The investment funds will be used to continue developing new and innovative services, grow the business’ user base and build a local business customer acquisition platform in what is one of the fastest growing sectors in the region. Intel Capital has also signed an agreement to invest in Sapato.ru, a leading ecommerce retailer in Russia specializing in footwear. Sapato is the country’s first online multi-brand shoe store with more than 200 brands and 5700 models. The announcement marks Intel Capital’s first investment in the ecommerce sector in Russia. The funds will be used to drive scale within the business, increase marketing efforts and streamline operations. “Innovation has been central to Russia’s development over the last few years. Our investments in these companies are proof of our continued commitment to the region and to supporting its entrepreneurial talent.” said Arvind Sodhani, President of Intel Capital and Executive Vice President of Intel. “Our support for these companies will give them access to global resources, knowledge and expertise to help drive their own growth and success.” Christian Morales, General Manager, Europe, Middle East, Africa of Intel Corporation commented, “We are really looking forward to working with two companies with such great potential.
    [Show full text]
  • Spatiotemporal Characterization of Contact Patterns in Dynamic Networks
    Ref. Ares(2014)1430495 - 05/05/2014 Mobile Opportunistic Traffic Offloading (MOTO) D3.2: Spatiotemporal characterization of contact patterns in dynamic networks Document information Edition 13 Date 29/04/2014 Status Edition Editor UPMC Contributors UPMC, TCS, CNR, INNO D3.2 Spatiotemporal characterization of contact patterns in dynamic networks Contents 1 Executive summary 4 2 Introduction 4 3 Contact patterns under a unifying framework 5 3.1 The SPoT Mobility Framework . .5 3.1.1 The social and spatial dimensions of human mobility . .6 3.1.2 From meeting places to geographical locations . .7 3.1.3 The temporal dimension of user visits to meeting places . .8 3.2 Analysis of real user movements . .9 3.3 Testing the framework flexibility . 10 3.4 Testing the framework controllability . 10 3.4.1 Validation . 11 3.5 Final remarks . 12 4 Impact of duty cycling on contact patterns 13 4.1 Problem statement . 13 4.2 The case of exponential intercontact times . 14 4.2.1 Computing N ....................................... 14 4.2.2 Computing the detected intercontact times . 15 4.2.3 Validation . 15 4.3 The effect of duty cycling on the delay . 17 4.4 Energy, traffic, and network lifetime . 17 4.5 Final remarks . 20 5 Contacts and intercontacts beyond one hop 20 5.1 Defining a new vicinity for opportunistic networks . 21 5.2 The limits of the binary assertion . 23 5.2.1 Datasets . 23 5.2.2 Binary assertion illustration . 25 5.2.3 Missed transmission possibilities . 25 5.3 κ-vicinity analysis . 26 5.3.1 The seat of κ-vicinities: connected components .
    [Show full text]
  • Безопасность Данных Мобильных Приложений. Мифы И Реальность Юрий Чемёркин Multi-Skilled Security Expert Зао «Перспективный Мониторинг»
    БЕЗОПАСНОСТЬ ДАННЫХ МОБИЛЬНЫХ ПРИЛОЖЕНИЙ. МИФЫ И РЕАЛЬНОСТЬ ЮРИЙ ЧЕМЁРКИН MULTI-SKILLED SECURITY EXPERT ЗАО «ПЕРСПЕКТИВНЫЙ МОНИТОРИНГ» Компания «Перспективный мониторинг» была создана в 2007 году как исследовательское подразделение группы компаний «ИнфоТеКС». Сегодня в компании развиваются направления: Коммерческий Центр мониторинга информационной безопасности (SOC). Threat Intelligence и разработка правил для средств защиты информации. Разработка средств мониторинга и аналитики. Практики безопасной разработки ПО. Исследования защищённости информационных систем. Безопасность мобильных устройств, приложений и сетей. http://amonitoring.ru PENTESTER & DEVELOPERS https://youtu.be/Nh11A41klL4?t=50s APP INSECURITY. WARNING Everything presented further contains information for educational purposes and only with using only your data & licenses. Moreover, to each app presented here was not applied any techniques and actions such as: modifying, decompiling, disassembling, decrypting and other actions with the object code of any Program, aimed at obtaining source codes of any Program Also, as known, the User may make a modification of the Software solely for his or hers own use and reverse engineering for debugging such modifications. ITR RESEARCH RESULTS. WHY CONSUMER UNINSTALLED MOBILE APPS https://www.itr.co.uk/mobile-app/ MOBILE APPS BING BANG – Y2011 - Y2014 - Y2017 Y2011 – viaForensics, which runs the appWatchdog web page, checked whether an app encrypted passwords, user names, or actual email content before storing it on the phone. A full pass meant that all three were stored in encrypted form. An app received a warning if the user name was left in plain text but password and content were encrypted. If either the password or content was stored in plain text, the app failed http://www.cbsnews.com/news/want-to-protect-your-emails-dont-use-these-11-android-and-iphone-email-apps/ Y2014 – Researchers find data leaks in Instagram, Grindr, OoVoo and more.
    [Show full text]
  • A 2012 Update on Internet in Russia the RUSSIAN WEB UNTANGLED
    ]A INDEPENDENT TECHNOLOGY RESEARCH SECTOR UPDATE JUNE 2012 DIGITAL MEDIA 2012 Update on Internet in Russia THE RUSSIAN WEB UNTANGLED Relentless Audience Growth Russia’s Internet audience is now the largest in Europe at 51m monthly users, ahead of Germany which it passed in Q4 2011. Yet with online penetration below 60% outside Moscow and St. Petersburg, we forecast continued strong growth in Internet audience in the rest of the country (the “regions”). Online Monetisation Powering Ahead Now that Russia has achieved European leadership in online audience, e- commerce and digital advertising are in its sight. While local issues remain, the Russian Internet ecosystem continues to develop, and audience monetisation is ramping up. Distinctive Development Path The vibrant local Internet community, largely centred in Moscow and St. Petersburg, continues to invent Russian-specific ways to define the web, with social and logistics as key areas of home-grown innovation. Local champions continue to dominate the Internet in key categories, and have actually improved their leadership in the past year compared to their international peers. Investment Activity Mirroring Market Development Foreign investments in the Russian Internet space have increased markedly in the past year, as funds and strategics alike are increasingly keen to position themselves in such a fast-growing opportunity. Conversely, the local investors’ ecosystem has continued to develop, and several sophisticated specialist funds have emerged that are now also looking to invest abroad. Conclusions GUILLAUME BONNETON [email protected] We foresee continued double-digit growth in key metrics for the remainder of London: +44 207 101 7578 this decade.
    [Show full text]
  • The Rise of Security Assistants Over Security Audit Services Yury Chemerkin Multi-Skilled Security Expert Advanced Monitoring Yury Chemerkin
    THE RISE OF SECURITY ASSISTANTS OVER SECURITY AUDIT SERVICES YURY CHEMERKIN MULTI-SKILLED SECURITY EXPERT ADVANCED MONITORING YURY CHEMERKIN I have ten years of experience in information security. I‘m a multi-skilled security expert on security & compliance and mainly focused on privacy and leakage showdown. Key activity fields are EMM and Mobile &, Cloud Computing, IAM, Forensics & Compliance. I published many papers on mobile and cloud security, regularly appears at conferences such as CyberCrimeForum, HackerHalted, DefCamp, NullCon, OWASP, CONFidence, Hacktivity, Hackfest, DeepSec Intelligence, HackMiami, NotaCon, BalcCon, Intelligence-Sec, InfoSec NetSysAdmins, etc. LINKEDIN: HTTPS://WWW.LINKEDIN.COM/IN/YURYCHEMERKIN TWITTER: @YURYCHEMERKIN EMAIL: [email protected] MOBILE PROTECTION & ISSUES 1. Data 2. App 3. OS 4. Device 5. Network 6. Compliance MOBILE PROTECTION & ISSUES 1. Data 2. App 3. OS 4. Device 5. Network 6. Compliance UNDERSTANDING DATA PROTECTION Different apps contain the same data values (same passwords, passport data, so on…) Some apps provides a worse protection level than other to protect particular data item If you use the same data (values), the worst app is your max protection level equals the minimum (worst) Valuable data is not only credentials, location, passport and bank data Valuable data is main data of app, like pics of Instagram, chats of Viber UNDERSTANDING DATA PROTECTION OVER DIFFERENT APPS. NETWORK DATA ITEMS Travel Data, Location Data, User Profile Data Uber Taxi, No Protection Yandex Meridian, Taxi Cris Taxi SSL Pinning Bucuresti, Taxi apps (RU) UNDERSTANDING DATA PROTECTION OVER DIFFERENT APPS. NETWORK DATA ITEMS Any data MITM with crafted cert (trust British to root certs) Airways, and Android Anywayanyday, Sberbank SSL Pinning Delta, Aeroflot, and iOS Sberbank ‘British Airways for iOS & Android’ have all data SSL Pinned, except booking data that MITMed with preinstalled/crafted CERT MOBILE PROTECTION & ISSUES 1.
    [Show full text]
  • Deal Notes 2011
    FIRST HALF DEAL NOTES 2011 M&A and Investments Review for the Marketing, DEAL NOTES Media, Technology, and Service Industries 1H11 Marketing, Media, Technology and Service Industries Transaction Activity Up 241 Percent; Deal Value Up 193 Percent on a Year-Over-Year Basis 1H11 Review: 1,353 Transactions Totaling $63.3 Billion Digital Media/Commerce Most Active and Highest Value Segment in 1H11 With 577 Transactions and $29.9 Billion in Deal Value Mergers and acquisitions and investment activity in the Marketing, Media, Technology and Service industries MARKETING, MEDIA, TECHNOLOGY & SERVICE INDUSTRIES 1H11 M&A AND INVESTMENT ACTIVITY grew 241 percent in the first half of 2011, while ($ in Millions) aggregate transaction value increased 193 percent, compared to 1H10. During the first half of 2011, Petsky Digital Media/ Commerce Prunier tracked 1,353 transactions for a total of $63.3 $29,937 billion across six broad segments: Digital Advertising, Agency/Consulting, Marketing Technology, Digital Digital Agency/ Advertising Consulting Media/Commerce, Software & Information and $2,937 $2,639 Marketing Services. Digital Media/Commerce was the most active and highest value segment with 577 transactions worth $29.9 billion in deal value. While strategic buyers accounted for approximately half of the combined M&A and investment activity, their Marketing Software & transactions represented 64 percent of the total value. Technology Information $9,338 Marketing $15,060 Venture and growth capital investors announced 705 Services transactions worth $13.8 billion. While there were $3,369 only 37 private equity buyout transactions, the deals accounted for $9.0 billion in value. (Continued on page 2) IN THIS ISSUE MARKETING, MEDIA, TECHNOLOGY & SERVICE INDUSTRIES M&A and Investments Overview 1 M&A AND INVESTMENT ACTIVITY: 2Q10 - 2Q11 Monetizing Facebook: Advertisers, Developers Look to Capitalize ($ in Billions) on Explosive Growth in Facebook Applications Platform 3 The DMP Debate: The Benefits of Pure Play vs.
    [Show full text]
  • Application of Online Marketing Methods and SEO Technologies for Web Resources Analysis Within the Region
    Application of Online Marketing Methods and SEO Technologies for Web Resources Analysis within the Region Volodymyr Kuchkovskiya, Vasyl Andrunyka, Maksym Krylyshyna, Lyubomyr Chyrunb, Anatolii Vysotskyic, Sofia Chyrunc, Nataliia Sokulskad, Ilona Brodovskae a Lviv Polytechnic National University, S. Bandera Street, 12, Lviv, 79013, Ukraine b Ivan Franko National University of Lviv, University Street, 1, Lviv, 79000, Ukraine c Anat Company, Chervona Kalyna Avenue, 104, Lviv, 79049, Ukraine d Hetman Petro Sahaidachnyi National Army Academy, Heroes of Maidan Street, 32, Lviv, 79012, Ukraine e Limited Liability Company Financial Company Absolute Finance, E. Konovaltsya Street, Kyiv, 01133, Ukraine Abstract This article presents the content analysis methods for information Web resources within a particular region. The model describes content analysis for processing Web resources in online marketing and simplifies the content automation management technology. The main problems of semantic and syntactic content analysis and functional services for textual content management are analysed. The rapid growth of Internet and e-business facilitates the publication and moderation of articles, which offers an intelligent system of marketing decisions to distribute content from a specific region to a particular target audience. The article describes developing information technology for processing Web resources of e-commerce based on online marketing and SEO methods. A new approach to the e-business processes application and implementation to such intelligent
    [Show full text]
  • 104 Social Network As the Tool for Commercializing Media Content
    Social Network as the Tool for Commercializing Media Content Kamoliddin Tursunpulatovich Beknazarov1 1. PhD doctoral student of University of Journalism and Mass Communication of the Republic of Uzbekistan, Tashkent, Uzbekistan [email protected] Abstract: The article describe the feature of the Internet in front of other communication channels is that communication is possible both with Internet users (interpersonal interaction), and with the information provided (machine interaction), development of the interactivity of the Internet, users have the opportunity to use audio-visual channels for transmitting information through the Internet. [Beknazarov K.T. Social Network as the Tool for Commercializing Media Content. Rep Opinion 2020;12(3):104-107]. ISSN 1553-9873 (print); ISSN 2375-7205 (online). http://www.sciencepub.net/report. 8. doi:10.7537/marsroj120320.08. Keywords: internet, communication, news channel, public. 1. Introduction - the third is a full-fledged independent online Already, it is safe to say that online publications media. and Internet representations of news agencies have On the Internet, such an integral feature of the become quite an effective communication channel. An media as periodicity is manifested in a new way. We important argument in favor of electronic resources is can say that the generally accepted idea in the media the fact that today, for most journalists of traditional community about the regularity of publications publications, the Internet has become one of the main (publication, broadcast) of print media, radio and sources of information. According to the Public television programs in the new environment “does not Opinion Foundation, in the fall of 2010, the work”. True, the daily, weekly, monthly frequency of proportion of Internet users among the adult content updates is transferred from the parent offline population of the country is 40% (or 12 million publications to their online versions, but even in this people).
    [Show full text]