DOCSLIB.ORG

(12) Patent Application Publication (10) Pub. No.: US 2012/0308486A1 Singer Et Al

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
(12) Patent Application Publication (10) Pub. No.: US 2012/0308486A1 Singer Et Al US 2012O3O8486A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2012/0308486A1 Singer et al. (43) Pub. Date: Dec. 6, 2012 (54) FRAGRANCE AND/OR FLAVORING Publication Classification COMPOSITIONS CONTAINING (51) Int. Cl. DOXOLANES A6IR 8/49 (2006.01) C07D 317/12 (2006.01) C07D 31 7/72 (2006.01) (75) Inventors: Emilie Singer, Holzminden (DE); A61O 1704 (2006.01) Bernd Hölscher, Halle (DE) A2.3L 2/56 (2006.01) A61O 15/00 (2006.01) A61O II/00 (2006.01) (73) Assignee: SYMRISE AG, Holzminden (DE) CLID 3/50 (2006.01) A2.3L. I./226 (2006.01) (21) Appl. No.: 13/473,053 A61O 13/00 (2006.01) A61O 19/00 (2006.01) (52) U.S. Cl. ................. 424/49; 512/12: 512/9; 549/430; (22) Filed: May 16, 2012 549/341; 424/59; 514/772; 424/65; 510/103; 426,536 Related U.S. Application Data (57) ABSTRACT (60) Provisional application No. 61/486.998, filed on May The present invention primarily relates to the use of diox olanes of the following Formula (I) as fragrance and/or fla 17, 2011. Voring Substances, certain perfume and/or flavoring compo sitions comprising these dioxolanes and corresponding perfumed and/or flavored items. (30) Foreign Application Priority Data The present invention also relates to a method for producing the dioxolanes of Formula (I) and certain new dioxolanes May 17, 2011 (EP) ................................ 11 166440.5 according to Formula (I). US 2012/030848.6 A1 Dec. 6, 2012 FRAGRANCE AND/OR FLAVORING in the process. In the context of the present invention, there COMPOSITIONS CONTAINING fore, no fragrance Substances are sought which exclusively or DOXOLANES predominantly Smell of pineapple or impart a pineapple note. 0011 Furthermore these fragrance and/or flavoring sub stances preferably have positive secondary characteristics, 0001. The present invention primarily relates to the use of preferably odor-enhancing characteristics and/or have the dioxolanes of Formula (I) defined below as fragrance and/or flavoring Substance, certain fragrance and/or flavoring com capacity to have odor and/or taste-enhancing characteristics positions comprising these dioxolanes and correspondingly and/or in combination with other fragrance and/or flavoring perfumed and/or flavored items. Substances to round offorto increase their naturalness, fresh 0002 The present invention also relates to a method for ness, (mouth)fill, (radiant) power and/or radiance and/or the producing the dioxolanes of Formula (I) and certain new increase the diffusivity of a fragrance mixture. dioxolanes according to Formula (I). 0012. This object was achieved by the use of a compound 0003 Because of the general scarcity of natural fragrance according to Formula (I) components, the changes required to keep up with changing flavor preferences and the ever-increasing need for new fra grances, which on their own or in the form of compositions (I) constitute valuable fragrances or perfumes with interesting scents, there continues also to be a need for compounds with interesting fragrance qualities. 0004 Because of the increasing demand from consumers for new scents the perfume industry has a constant need for new fragrance substances with which to achieve novel effects in perfumes and in this way to create fashion trends. 0005. Despite a whole range of fragrance substances already being available the perfume industry also continues to including the stereosiomers, wherein have a general need for new fragrance Substances, in particu 0013 R1 and R2 in each case and independently of one lar those which, in addition to their primary, that is to say odor, another is either hydrogen or methyl, preferably hydrogen, characteristics also have positive secondary characteristics, and Such as for example a higher stability under certain applica 0014) a) R3 and R4—together with the ketal carbon atom tion conditions, a high extension, a high radiant power, good of the dioxolane ring form a ring with a total of 5, 6, 7 or diffusivity (e.g. a good spatial effect), fullness, power and/or 8 ring carbonatoms, where the ring optionally contains one naturalness, odor-enhancing characteristics or also improved or two double bonds and/or optionally 1 to a maximum of dermatological characteristics compared with fragrance Sub 3 oxygen atoms, and wherein the ring is optionally Substi stances with comparable primary odor characteristics. tuted by one or a plurality of branched or unbranched, 0006. The perfume industry thus has a basic need for more bridged or unbridged, alkyl groups, alkenyl groups, fragrance Substances that are suitable for the production of cycloalkyl groups, cycloalkenyl groups, aryl groups, aryl fragrance compositions or perfumed items. There is in par alkyl groups, alkoxy alkyl groups or alkoxy aryl groups, ticular a need for fragrances which through the abovemen tioned technical characteristics lead to increased use of fra and wherein R3 and R4 together comprise in total 3 grance compositions and perfume oils. through 30 carbon atoms, 0007 WO 02/085294 describes various acetals for block 0.015 or ing or reducing the unpleasant odor of certain acids. The 0016 b) R3 is either hydrogen oran organic radical with 1 acetals disclosed there can, according to WO 02/085294, be through 15 carbon atoms, wherein the organic radical used in various compositions, inter alia in the area of body optionally contains 1 to a maximum of 3 oxygen atoms, care and in cleaning agents. preferably R3 is either hydrogen or a saturated or unsatur 0008 DE 25 41 438 describes dioxolane aldehyde fra ated, aromatic oraliphatic, branched or unbranched, cycli grance substances, which were obtained there by the hydro cal or linear, bridged or unbridged structure element with 1 formylation of the corresponding dioxolanes. The various through 15 carbon atoms, wherein the structure element dioxolanes disclosed in DE 2541 438 served there as starting optionally contains 1 to a maximum of 3 oxygenatoms and materials for the production of the dioxolane aldehyde fra the structure element is optionally substituted by 1 to a grance substances. The only dixolane described in DE 2541 maximum of 3 alkyl- and/or alkenyl groups and/or by one 438 with regard to odor is 2-hexyl-4-vinyl-1,3-dioxolane, or two hydroxy groups, which according to DE 25 41 438 has a fruity odor of pine 0017 and apple. 0018 R4 contains an organic radical with 2 through 15 0009 EP 1992 606A1 discloses certain alkene acetals as carbonatoms, wherein the organic radical optionally contains fragrance Substances. The fragrance Substances disclosed in 1 to a maximum of 3 oxygen atoms, preferably R4 is a EP 1992 606 A1 are derived from 4-pentenals, and have in saturated or unsaturated, aromatic or aliphatic, branched or particular a 2.3,3-trimethyl-4-pentenyl structure element. unbranched, cyclical or linear, bridged or unbridged structure 0010 So the primary object was to find fragrance and/or element with 2 through 15 carbon atoms, wherein the struc flavoring Substances having an interesting sensory profile and ture element optionally contains 1 to a maximum of 3 oxygen which are Suitable for use as fragrance Substances in perfum atoms and the structure element is optionally substituted by 1 ery or as flavoring Substances for flavoring consumable to a maximum of 3 alkyl-and/or alkenyl groups and/or by one preparations, without themselves imparting a pineapple note or two hydroxy groups US 2012/030848.6 A1 Dec. 6, 2012 0019 and wherein at least one of the following conditions 0033 or applies: 0034 2. R4 a mono-, bi- or tricyclic alkyl system, which is 0020 i. where R4 is a branched or unbranched alkyl radi optionally substituted by one, two or a cal with 4 through 15 carbon atoms with optionally one, 0035 plurality of alkyl radicals, hydroxy radicals or two or a plurality of double bonds, at position3 to position alkoxy radicals, wherein the alkyl radicals are preferably 4 of R4 a carbon-carbon single bond is present selected from the group consisting of methyl, ethyl, propyl. 0021 or 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1.1- 0022 ii. where R4 is a branched or unbranched alkyl radi dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 3-me cal with 2 through 15 carbon atoms with optionally one, thylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1,1- two or a plurality of double bonds, R3 is not hydrogen, dimethylpropyl, 1,2-dimethylpropyl, 1-methylpentyl, 0023 as a fragrance and/or flavoring substance for impart 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1-dim ing, enhancing and/or modifying one, two or a plurality of ethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dim scents and/or flavors, wherein no scent and/or flavor of pine ethylbutyl, 2,3-dimethylbutyl, 3.3-dimethylbutyl, 1-ethylbu apple is imparted. tyl, 2-ethylbutyl, 1.1.2-trimethylpropyl. 1.2.2- 0024. To clarify: condition i. means that between the two trimethylpropyl, 1-ethyl-1-methylpropyl and 1-ethyl-2- carbon atoms at positions 3 and 4 of R4 in particular no methylpropyl. carbon-carbon double bond is present. 0036 or 0025 Preference is for compounds of Formula (I), 0037 3. R4 is a branched or unbranched alkyl radical with wherein 2 through 15 carbon atoms with one, two or a plurality of 0026 R1 and R2 in each case and independently of one another is either hydrogen or methyl, preferably hydrogen, double bonds or a ring system with 5, 6 or 7 carbon atoms and with one, two or a plurality of double bonds, 0038 and wherein at least one of the following conditions 0027 a) R3 and R4 together result in a cyclical alkyl applies: system with 5, 6, 7 or 8 carbon atoms, which is optionally substituted by one or a plurality of branched or unbranched 0039 i.
Load more

Recommended publications
  • (12) United States Patent (10) Patent No.: US 6,239,087 B1 Mao Et Al
    USOO6239087B1 (12) United States Patent (10) Patent No.: US 6,239,087 B1 Mao et al. (45) Date of Patent: May 29, 2001 (54) DETERGENT COMPOSITIONS (56) References Cited CONTAINING FRAGRANCE PRECURSORS U.S. PATENT DOCUMENTS AND THE FRAGRANCE PRECURSORS THEMSELVES 2,448,660 9/1948 Croxall et al. ....................... 568/600 2,490,337 12/1949 Croxall et al. ....................... 568/594 (75) Inventors: Hsiang Kuen Mao, Kobe (JP); Joseph 5,288,423 * 2/1994 Behan et al...... ... 252/174.11 Paul Morelli; Henry Cheng Na, both 5,447,644 9/1995 Guenin et al. ........................ 252/8.6 5,500,138 3/1996 Bacon et al. ......................... 510/102 of Cincinnati, OH (US); Robert Ya-Lin 5,500,154 3/1996 Bacon et al. ......................... 510/102 Pan, Kobe (JP); Mark Robert Sivik, 5,656,584 * 8/1997 Angell et al. ........................ 510/441 Fairfield, OH (US) 5,668,862 9/1997 Price et al. ........................... 568/594 (73) Assignee: The Procter & Gamble Company, 5,731,282 3/1998 Duquesne ............................. 510/423 Cincinnati, OH (US) OTHER PUBLICATIONS Rothman et al., “Enol Esters XVI: Enol Ethers in Synthe Notice: Subject to any disclaimer, the term of this sis”: Eastern Regional Research Laboratory, Philadelphia, patent is extended or adjusted under 35 Pennsyvania, pp. 376-377, (Jun. 1972). U.S.C. 154(b) by 0 days. Dejarlais et al., “Preparation of Some Ethyl Higher-Alkyl Appl. No.: 09/155,140 Acetals and Their Conversion to Vinyl Ethers': Northern (21) Regional Research Laboratory, Peoria, Illinois, pp. 241-243, (22) PCT Fed: Mar. 22, 1996 (May 1961). (86) PCT No.: PCT/US96/04060 * cited by examiner S371 Date: Sep.
    [Show full text]
  • Potential Use of Polymers and Their Complexes As Media for Storage and Delivery of Fragrances T ⁎ ⁎ Rajnish Kaura,1, Deepak Kukkarb,1, Sanjeev K
    Journal of Controlled Release 285 (2018) 81–95 Contents lists available at ScienceDirect Journal of Controlled Release journal homepage: www.elsevier.com/locate/jconrel Review article Potential use of polymers and their complexes as media for storage and delivery of fragrances T ⁎ ⁎ Rajnish Kaura,1, Deepak Kukkarb,1, Sanjeev K. Bhardwajc,1, Ki-Hyun Kimd, , Akash Deepc, a Department of Physics, Panjab University, Sector 14, Chandigarh 160014, India b Department of Nanotechnology, Sri Guru Granth Sahib World University, Fatehgarh Sahib, Punjab 140406, India c Central Scientific Instruments Organization (CSIR-CSIO), Sector 30 C, Chandigarh 160030, India d Department of Civil and Environmental Engineering, Hanyang University, Seoul 04763, Republic of Korea ARTICLE INFO ABSTRACT Keywords: The use of fragrances is often essential to create an elegant, welcoming, or exhilarating environment. Through Polymeric complexes encapsulation, the release and delivery of fragrances are customized in many consumer products. For such Porous materials purposes, cost-effective techniques have been developed and employed with the use of various polymers and Composite porous organic materials to efficiently impart fragrances to foods and various other consumer products. After Adsorption capacities entrapment or uptake/storage of fragrant molecules within a polymeric complex, the properties can be in- Fragrance delivery vestigated by automated thermal desorption (ATD) analysis. For efficient delivery, fragrances are adsorbed (or entrapped) in some media (e.g., fabric or paper). The release of such entrapped fragrances usually is achieved by spraying. Fragrances can be also loaded in a media by purging aroma gases or by adding fragrance essence directly into a liquid medium. Porous materials, such as zeolites, have been traditionally used for air purification as well as in cosmetics and similar applications.
    [Show full text]
  • Cellulose As a Delivery System of Raspberry Juice Volatiles and Their Stability
    molecules Article Cellulose as a Delivery System of Raspberry Juice Volatiles and Their Stability Josipa Vukoja 1, Anita Pichler 1, Ivana Ivi´c 1, Josip Šimunovi´c 2 and Mirela Kopjar 1,* 1 Faculty of Food Technology, Josip Juraj Strosmayer University, F. Kuhaˇca18, 31000 Osijek, Croatia; [email protected] (J.V.); [email protected] (A.P.); [email protected] (I.I.) 2 Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC 27695, USA; [email protected] * Correspondence: [email protected] Academic Editors: Encarna Gómez-Plaza and Rocio Gil-Muñoz Received: 8 May 2020; Accepted: 3 June 2020; Published: 5 June 2020 Abstract: Formulation of delivery systems for active ingredients is of increasing importance for the food industry. For that purpose, we selected cellulose as a carrier polymer of raspberry volatiles. Freeze-dried cellulose/raspberry complexes were prepared by complexation of raspberry juice (constant amount) and cellulose (2.5%, 5%, 7.5% and 10%). In our study, cellulose was shown as a good carrier of raspberry juice volatiles. Thirty-nine volatiles were detected in raspberry juice while 11 of them were lost during preparation of the complexes. Berry flavor note was the dominant one in raspberry juice (40% of overall flavor), followed by citrus and woody notes (each around 18% of overall flavor) and floral, fruity, and green (each around 8% of overall flavor). Cellulose/raspberry complexes had different flavor profiles, but a berry flavor note was still the dominant one in all complexes. These results suggest an efficient plant-based approach to produce value-added cellulose/volatile dry complexes with possible utility as food flavoring ingredients.
    [Show full text]
  • Designated Lists Can Be Viewed Here
    INGREDIENT DISCLOSURE 7055 Lindell Rd, Las Vegas, NV 89118 800.293.4698 | www.bradyindustries.com Ingredient Disclosure Designated List Links SB 258, Cleaning Product Right to Know Act of 2017 List Description 1 CA Prop 65 2 EU CMRs 3 EU Endocrine Disruptors 4 IRIS Neurotoxicants 5 IRIS Carcinogens 6 EU PBTs 7 Canada PBTs 8 EU Respiratory Sensitizers 9 IARC Carcinogens 10 ATSDR Neurotoxicants 11 US EPA Priority Chemicals List 12 US NTP Reproductive or Developmental Toxicants 13 US EPA PBTs 14 WA PBTs 15 US NTP Carcinogens 16 CA NLs 17 CA MCLs 18 CA TACs 19 CA Priority Pollutants 20 CA Non-Cancer Hazards 21 CA Priority Chemicals 22 Marine Priority Action Chemicals 23 EU Fragrance Allergens NFC Nonfunctional Constituents N/A Not Applicable Fragrance Allergen Ingredient CHEMICAL NAME CAS NUMBER 1-Phenylethanone 98-86-2 3-(1,3-Benzodioxol-5-yl)-2-methylpropanal 1205-17-0 Acetaldehyde 75-07-0 a-Isomethyl ionone 127-51-5 Amyl Cinnamal 122-40-7 AmylCinnamyl Alcohol 101-85-9 Anise Alcohol 105-13-5 Benzophenone 119-61-9 Benzyl alcohol 100-51-6 Benzyl benzoate 120-51-4 Benzyl Cinnamate 103-41-3 Benzyl Salicylate 118-58-1 BHA 25013-16-5 Biphenyl 92-52-4 Butylphenyl Methylpropional (Lilial) 80-54-6 Cinnamal 104-55-2 Cinnamyl Alcohol 104-54-1 Citral 5392-40-5 Citronellol 106-22-9 Citronellol (3,7-Dimethyloct-6-en-1-ol) 106-22-9 Coumarin 91-64-5 Cyclotetrasiloxane 556-67-2 Diethyl phthalate 84-66-2 Estragole (1-Allyl-4-methoxybenzene) 140-67-0 Eugenol (4-Allyl-2-methoxyphenol) 97-53-0 Farnesol 4602-84-0 Geraniol 106-24-1 Hexanedioic Acid, Bis(2-ethylhexyl)
    [Show full text]
  • Annex I: Clinical Evidence Regarding Sensitisation to Individual Fragrance Chemicals and to Natural Extracts
    Annex I: Clinical evidence regarding sensitisation to individual fragrance chemicals and to natural extracts Contents Single chemicals ............................................................................. 2 Catalogue of single chemicals evaluated ............................................. 5 Natural extracts / essential oils ........................................................68 Catalogue of natural extracts / essential oils evaluated ........................68 References ....................................................................................99 1 Single chemicals Often, results with the single constituents of the FM I or, yet more rarely, FM II, are presented in one paper. As the main ordering is by allergen, core information on these studies is presented in a tabular format and referenced by a unique acronym in the single sections, to avoid redundancy. Regarding nomenclature, terms which are often not officially an INCI Name but Perfuming Name as listed by CosIng are used. Table 1: Background information on studies reporting results with (all) single constituents of the FM I (amyl cinnamal, cinnamyl alcohol, cinnamal, eugenol, geraniol, hydroxycitronellal, isoeugenol, EVERNIA PRUNASTRI) Reference Country Study period, Comments by Patients reviewers Larsen 2002 c 7 industrial countries Prior to 2002 Test concentrations (1) worldwide n=218 patients with identified as non- known contact allergy irritating in serial to fragrance dilution testing in 20 ingredients healthy volunteers Utrecht 1999 Utrecht, The Netherlands
    [Show full text]
  • Dictionary of Contact Allergens: Chemical Structures, Sources And
    51_943_1106* 05.11.2005 12:17 Uhr Seite 943 Chapter 51 Dictionary of Contact Allergens: 51 Chemical Structures, Sources and References Christophe J. Le Coz, Jean-Pierre Lepoittevin 51.1 Introduction This chapter has been written in order to familiarize the reader with the chemical structure of chemicals implicated in contact dermatitis, mainly as haptens respon- sible for allergic contact dermatitis. For each molecule, the principal name is used for classification. We have also listed the most important synonym(s), the Chemical Abstract Service (CAS) Registry Number that characterizes the substance, and its chemical structure. The reader will find one or more relevant literature references. As it was not possible to be exhaustive, some allergens have been omitted since they were obsolete, extremely rarely implicated in contact dermatitis, their case reports were too imprecise or they are extensively treated in other chapters of the textbook. From a practical chemical point of view, acrylates, cyanoacrylates and (meth)acry- lates, cephalosporins, and parabens have been grouped together. 1. Abietic acid CAS Registry Number [514–10–3] Abietic acid is probably the major allergen of colophony, along with dehydroabietic acid,by way of oxidation products.Its detection in a material indicates that allergen- ic components of colophony are present. Suggested Reading Bergh M, Menné T, Karlberg AT (1994) Colophony in paper-based surgical clothing. Contact Der- matitis 31 : 332–333 Karlberg AT, Bergstedt E, Boman A, Bohlinder K, Lidén C, Nilsson JLG,Wahlberg JE (1985) Is abiet- ic acid the allergenic component of colophony? Contact Dermatitis 13 : 209–215 Karlberg AT, Bohlinder K, Boman A, Hacksell U, Hermansson J, Jacobsson S, Nilsson JLG (1988) Identification of 15-hydroperoxyabietic acid as a contact allergen in Portuguese colophony.
    [Show full text]
  • Fragrance Composition Duftstoffzusammensetzung Composition Parfumante
    (19) TZZ¥ ¥ZZ_T (11) EP 3 279 300 B1 (12) EUROPEAN PATENT SPECIFICATION (45) Date of publication and mention (51) Int Cl.: of the grant of the patent: C11B 9/00 (2006.01) A61K 8/34 (2006.01) 27.03.2019 Bulletin 2019/13 A61Q 5/02 (2006.01) A61Q 19/10 (2006.01) C07C 29/145 (2006.01) C07C 31/125 (2006.01) (2006.01) (2006.01) (21) Application number: 17184231.3 C11D 3/50 D06M 13/144 C07B 61/00 (2006.01) (22) Date of filing: 30.05.2013 (54) FRAGRANCE COMPOSITION DUFTSTOFFZUSAMMENSETZUNG COMPOSITION PARFUMANTE (84) Designated Contracting States: • Asada, Takahiro AL AT BE BG CH CY CZ DE DK EE ES FI FR GB Wakayama, 640-8580 (JP) GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO • Toki, Naotoshi PL PT RO RS SE SI SK SM TR Wakayama, 640-8580 (JP) (30) Priority: 01.06.2012 JP 2012126075 (74) Representative: Hoffmann Eitle Patent- und Rechtsanwälte PartmbB (43) Date of publication of application: Arabellastraße 30 07.02.2018 Bulletin 2018/06 81925 München (DE) (62) Document number(s) of the earlier application(s) in (56) References cited: accordance with Art. 76 EPC: WO-A1-2010/091969 DE-A1-102010 002 104 13796988.7 / 2 857 482 US-A1- 2011 081 393 (73) Proprietor: KAO CORPORATION • Masahiro Manabe ET AL: "The counterion Tokyo 103-8210 (JP) releasing effect and the partition coefficient of branched alkanols in ionic micellar solution", (72) Inventors: COLLOID & POLYMER SCIENCE, vol. 280, no. 10, • Ueda, Junko 1 October 2002 (2002-10-01), pages 929-935, Wakayama, 640-8580 (JP) XP055477085, DE ISSN: 0303-402X, DOI: • Ataka, Yoshiharu 10.1007/s00396-002-0710-3 Wakayama, 640-8580 (JP) Note: Within nine months of the publication of the mention of the grant of the European patent in the European Patent Bulletin, any person may give notice to the European Patent Office of opposition to that patent, in accordance with the Implementing Regulations.
    [Show full text]
  • OPINION on Fragrance Allergens in Cosmetic Products
    SCCS/1459/11 Scientific Committee on Consumer Safety SCCS OPINION on Fragrance allergens in cosmetic products The SCCS adopted this opinion at its 15th plenary meeting of 26-27 June 2012 SCCS/1459/11 Opinion on fragrance allergens in cosmetic products _________________________________________________________________________________________ About the Scientific Committees Three independent non-food Scientific Committees provide the Commission with the scientific advice it needs when preparing policy and proposals relating to consumer safety, public health and the environment. The Committees also draw the Commission's attention to the new or emerging problems which may pose an actual or potential threat. They are: the Scientific Committee on Consumer Safety (SCCS), the Scientific Committee on Health and Environmental Risks (SCHER) and the Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) and are made up of external experts. In addition, the Commission relies upon the work of the European Food Safety Authority (EFSA), the European Medicines Agency (EMA), the European Centre for Disease prevention and Control (ECDC) and the European Chemicals Agency (ECHA). SCCS The Committee shall provide opinions on questions concerning all types of health and safety risks (notably chemical, biological, mechanical and other physical risks) of non-food consumer products (for example: cosmetic products and their ingredients, toys, textiles, clothing, personal care and household products such as detergents, etc.) and services (for example: tattooing, artificial sun tanning, etc.). Scientific Committee members Jürgen Angerer, Ulrike Bernauer, Claire Chambers, Qasim Chaudhry, Gisela Degen, Elsa Nielsen, Thomas Platzek, Suresh Chandra Rastogi, Vera Rogiers, Christophe Rousselle, Tore Sanner, Jan van Benthem, Jacqueline van Engelen, Maria Pilar Vinardell, Rosemary Waring, Ian R.
    [Show full text]
  • WO 2017/172568 Al 5 October 2017 (05.10.2017) P O P C T
    (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2017/172568 Al 5 October 2017 (05.10.2017) P O P C T (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61L 9/013 (2006.01) A61K 8/46 (2006.01) kind of national protection available): AE, AG, AL, AM, CUB 9/00 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, (21) Number: International Application DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, PCT/US20 17/024230 HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, (22) International Filing Date: KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, 27 March 2017 (27.03.2017) MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (25) Filing Language: English RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (26) Publication Language: English TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: 62/3 13,83 1 28 March 2016 (28.03.2016) US (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (71) Applicant: THE PROCTER & GAMBLE COMPANY GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, [US/US]; One Procter & Gamble Plaza, Cincinnati, Ohio TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, 45202 (US).
    [Show full text]
  • Halal Positive List (Eng).Pdf
    Attachment of Decree Number: SK12/DIR/LPPOM MUI/VI/20 HALAL POSITIVE LIST OF MATERIALS Halal Positive List of Materials consists of non-critical materials, in terms of their halalness status, commonly used in processing industries. This material list was made based on the assessment of LPPOM MUI refer to the literature, abundance in nature, and consideration of commercially production scales. Companies that using materials listed in Halal Positive List of Materials will get advantages as follows: 1. In selection process of new materials, materials listed in Halal Positive List of Materials already get material approval from LPPOM MUI automatically prior to use. 2. In process of incoming material checking, materials listed in Halal Positive List of Materials does not require the suitability checking of the material name, manufacture's name and country of origin. 3. In product registration process, materials listed in Halal Positive List of Materials does not require supporting document. If the materials use trade name which is different with material name, the material specification document is still required. During the audit process, the auditor may check the supporting documents of material when necessary. In Halal Positive List of Materials, there is a description of materials that are prohibited from being used for food or cosmetics according to Indonesia Food and Drug Administration (BPOM) regulation (PERKA BPOM No. 07/2018 and PERKA BPOM No. 18/2015). So that it can be used as a reference for companies in order to meet regulations regarding the use of materials for products marketed in Indonesia. The "x" sign in the column Prohibited used based on BPOM Regulation indicates that the material is not allowed to be used for the mentioned product category.
    [Show full text]
  • List of 1500+ Chemicals with CAS Numbers Used in Fragrances And
    List of 1500+ Chemicals with CAS Numbers Used in Fragrances and Perfumes Acetal 105-57-7 Acetaldehdye phenethyl propyl acetal 7493-57-4 Acetaldehyde 75-07-0 Acetaldehyde ethyl cis-3-hexenyl acetal 28069-74-1 Acetaldehyde ethyl hexyl acetal 54484-73-0 Acetaldehyde ethyl isoeugenyl acetal 84029-92-5 Acetaldehyde ethyl linalyl acetal 40910-49-4 Acetaldehyde ethyl phenethyl acetal 2556-10-7 Acetaldehyde trans-3-hexenyl acetal 60763-40-8 Acetalpyrazine, 2- 22047-25-2 Acetanisole 100-06-1 Acetate C-11 112-19-6 Acetate C-12 112-66-3 Acetate C-7 112-06-1 Acetate C-8 112-14-1 Acetate C-9 143-13-5 Acethoxy-3-ethoxybenzaldehyde, 4- 72207-94-4 Acetic Acid 64-19-7 Acetoin 513-86-0 Acetone 67-64-1 Acetophenone 98-86-2 Acetovanillone 498-02-2 Acetoxy-1-ethynyl-2- sec-butylcyclohexane, 1- 37172-05 Acetoxy-3-butanone, 2- 4906-24-5 Acetoxy-3-ethoxybenzaldehyde, 4- 72207-94-4 Acetoxy-3-pentyltetrahydropyran, 4- 18871-14-2 Acetoxydihydrotheaspirane, 6- 57893-27-3 Acetoxyphenyl)-2-butanone, 4-(p- 3572-06-3 Acetyl carene 3608-11-5 Acetyl cedrene 32388-55-9 Acetyl isovaleryl 13706-86-0 Acetyl propionyl 600-14-6 ACETYL VALERYL 96-04-8 Acetyl-1,1,2,3,3,6-hexamethylindan, 5- 15323-35-0 Acetyl-1-methylpyrrole, 2- 932-16-1 Acetyl-2,5-dimethylthiophene, 3- 2530-10-1 Acetyl-2-5dimethylfuran, 3- 10599-70-9 Acetyl-2-thiazoline, 2- 29926-41-8 Acetyl-3,5(or 6)-dimethylpyrazine, 2- 54300-08-2 Acetyl-3-ethylprazine, 2- 32974-92-8 Acetyl-3-isopropyl-1,1,2,6-tetramethylindane 68140-48-7 Acetyl-3-methylpyrazine, 2- 23787-80-6 Acetyl-5-methylfuran, 2- 1193-79-9 Acetyl-6-t-butyl-1,
    [Show full text]
  • The Complementary Roles of Dynamic Headspace and Sorptive Extraction in the Analysis of Fragranced Consumer Products Using TD–GC–MS
    Application Released: November 2017 Application Note 135 The complementary roles of dynamic headspace and sorptive extraction in the analysis of fragranced consumer products using TD–GC–MS Summary Background to the sampling equipment This Application Note describes the analysis of three fragranced In this study, three sampling procedures were used, to consumer products – fabric conditioner, washing detergent and establish how well they performed for each sample: washing powder – using three sampling approaches in • Method A – Dynamic headspace sampling using the conjunction with analysis by thermal desorption–gas Micro-Chamber/Thermal Extractor™ (µ-CTE™) (Figure 1). chromatography–mass spectrometry (TD–GC–MS). As well as ™ comparing the analyte ranges covered by dynamic headspace • Method B – Headspace sorptive extraction using HiSorb sampling, headspace sorptive extraction and immersive sorptive probes (Figure 2). extraction, the ability of Markes’ re-collection technology to • Method C – Immersive sorptive extraction using HiSorb streamline method development and validation is discussed. probes. These three methods are outlined in Figure 3. Introduction The success of many personal care and household cleaning products has long depended on the precise mix of aroma- active compounds that they release. For example, manufacturers are continuously developing new formulations that offer different (or longer-lasting) fragrances, while consumers loyal to a well-established brand can notice even the slightest variation in fragrance quality. In addition, there has been increasing concern over the presence of potentially harmful compounds – such as allergens – in fragrance formulations. These factors have led to an ongoing need to monitor the volatile and semi-volatile organic compounds (VOCs and SVOCs) released by fragranced consumer products.
    [Show full text]