Saturday, April 14, 2018 High Congdon School of Health Sciences

Sponsored by:

synapse.cofc.edu Schedule

Time Event Room

8:00 Registration Lobby Breakfast Poster-Set-up

8:30 Opening Welcome Auditorium

8:45 - 9:45 Travel Awardees Oral Presentations Auditorium

10:00 - 11:00 Concurrent Session I Molecular Neurobiology Room 4090 and Drugs of Addiction Back-Yard-Brains Room 3027

11:00 - Noon Poster Session I Lobby

Noon - 1:00 Buffet Lunch 2nd Floor Ballroom

1:00 - 2:00 Concurrent Session II Cognition/Behavior & Room 4089 Injury/Repair Back-Yard-Brains Room 3027

2:15 - 3:15 Poster Session II Lobby

3:15 - 3:45 Flex Time Campus Tour Steering Committee Room 2047 Poster Judging Room 2062

3:45 - 4:45 Keynote Address Auditorium

5:00 - 5:15 Closing and Awards Auditorium

2 Congdon Hall of Health Sciences

FOURTH FLOOR

1 4 1 ANATOMY LAB 3 2 DEPT. OF PHYSICAL THERAPY ADMINISTRATION 4089 3 MEDICINAL AND PHARMACEUTICAL CHEMISTRY 4090 RESEARCH LAB 2 5 4 PHARMACOLOGY RESEARCH LAB

5 FRED WILSON SCHOOL OF PHARMACY FACULTY OFFICES

3 THIRD FLOOR 4

7 1 DEPT. OF PHYSICIAN 6 STANDARDIZED 5 6 ASSISTANT STUDIES CLIENT SUITE 2 ADMINISTRATION 3027 7 INFECTIOUS 2 SIMULATION LABS DISEASE LAB 1 8 3 CLINICAL SKILLS LAB 8 FRED WILSON SCHOOL OF 4 HISTORY AND PHARMACY PHYSICAL EXAM LAB ADMINISTRATION

5 BALLROOM

SECOND FLOOR 2

1 LOBBY 3 4 2047 2 PHYSICAL THERAPY NEUROSCIENCE LAB

3 VIRTUAL REALITY AND GAIT ANALYSIS LAB 2062 1 5 4 PHARMACY SKILLS LABORATORY SUITE

5 CALLICUTT AUDITORIUM

FIRST FLOOR

1 HUMAN BIOMECHANICS AND PHYSIOLOGY LAB 1 2 2 WILLED BODY PROGRAM 3 3 PHARMACY COLLABORATION SPACES AND 4 CLASSROOMS

4 MUSCULOSKELETAL LAB

HIGHPOINT.EDU

3 Notes

4 Keynote Speakers

Dr. Read Montague holds professorships in Physics at Virginia Tech, and in Psychiatry and Behavioral Medicine at Virginia Tech School of Medicine. He is the Director of both the Human Neuroimaging Laboratory and the Compu- tational Psychiatry Unit at Virginia Tech Carilion Research Institute where his team uses computational and experimental approaches to study decision-making, addiction, social exchanges, and the role of specific neurotransmitters and brain regions in cognition within normal and diseased patients. Dr. Montague is well regarded for his national and international speaking engagements, and his work has been featured on PBS’s “The Brain with David Eagleman,” in a Global TED talk, and in numerous scientific and popular articles.

Tim Marzullo, co-founder of Back-Yard-Brains, specializes in Neu- ro-Engineering with doctorate of Neuroscience from the University of Michigan. Before synthesizing and developing Back Yard Brains, Tim was a Lecturer at the University of Michigan and a research Engineer for NeurNexus Technologies, thus his “path to success” will be familiar, yet inspiring to students. His company is federally funded (National Institutes of Mental Health SBIR grant: -#2R44MH093334-03: Backyard Brains: Bringing Neurophysiology into secondary schools) and focused on outreach and neuroscience education.

5 Plenary Session — Travel Awardee Oral Presentations

1. Waugh, C. Escobedo, C. Kalantar, A. Ford, B. 2. Eppley KJ, Faust-Casey BK, Goodman JI, Gosine AE, Kraemer, B. Department of Biological Sciences, Bruce AA, Wilhelm JC. Department of Biology, Department Eastern Kentucky University of Psychology, Program of Neuroscience, of Charles- ton, Charleston, SC Activation of the p75 Neurotrophin Receptor in Degenerating Dopaminergic Neurons Subjected to Effects of Estrogen on Sensory Neuron Participation in Axon Oxidative Stress Regeneration Following Peripheral Nerve Injury.

The p75 neurotrophin receptor is a transmembrane protein Peripheral nerve injuries affect hundreds of thousands of people that promotes the death of neurons affected by various injuries each year in the alone. Despite the fact that periph- or pathological conditions. Tissue damage can lead to upreg- eral nerves have the ability to regenerate, functional recovery is ulation of pro-neurotrophins, ligands that bind and activate often very poor due to insufficient axon regeneration. Previous p75NTR. Upon activation, p75NTR is cleaved by TNF-α studies have shown that treatment with estrogen can significantly Converting Enzyme (TACE) and the gamma-secretase com- enhance the regeneration of motoneurons following peripheral plex, thereby releasing the intracellular domain of the recep- nerve injury; however, this has not yet been studied in sensory tor to activate downstream pro-apoptotic mediators. From neurons. Both sensory and motoneuron regeneration are nec- previous analyses of sympathetic neurons, we discovered that essary in order to obtain full functional recovery; therefore, the cleavage of p75NTR is induced by oxidative stress, a cellular present study examined the role of estradiol signaling in sensory condition associated with numerous types of pathological neuron participation and hypothesized that systemic estrogen conditions. Surprisingly, however, this mechanism of receptor treatment will increase the rate of axon regeneration in sensory activation did not require neurotrophins. Thus, ligand-inde- neurons following peripheral nerve injury. Male and female mice pendent activation of p75NTR in neurons subjected to oxida- were anesthetized and the common fibular branch of the right tive stress may underlie the ability of the receptor to promote sciatic nerve was cut and repaired using fibrin glue. Immediately degeneration of cells affected by a wide variety of pathological after transection surgery, mice were treated for two weeks with conditions. Whether oxidative stress-induced p75NTR activa- either estradiol-filled or unfilled (blank) capsules inserted in the tion contributes to neurodegeneration in the central nervous nape of their neck. Upon completion of estradiol or control system has not been explored. In the present study, we evaluate treatments, animals underwent a second surgery during which the contribution of p75NTR to oxidative stress-induced de- a retrograde tracer was applied 1.5mm distal to the original generation of midbrain dopaminergic neurons, a population of repair site in order to label the sensory neurons whose axons had cells particularly susceptible to Parkinson’s disease. To overcome regenerated at least that distance. Three days following retrograde limitations of primary cultured dopaminergic neurons for pro- labelling, all animals were sacrificed, and regeneration was quan- tein analysis, these investigations were conducted using LUH- tified by counting the number of neurons containing fluorescent MES cells, a population of conditionally-immortalized human tracer dye. Systemic estradiol treatment significantly increased the mesencephalic cells that can be differentiated to post-mitotic, number of labelled axons, and therefore indicates an increase in electrically active cells with morphological features and protein sensory neuron participation in axon regeneration. These findings expression profiles resembling mature dopaminergic neurons. demonstrate the ability of sensory axons to regenerate in a similar We have discovered that these dopaminergic cells abundantly manner as motoneurons, and show that estrogen treatment can express p75NTR and are susceptible to oxidative stress-asso- be used to increase the likelihood of full functional recovery ciated death induced by 6-hydroxdopamine (6-OHDA), a following peripheral nerve injury. compound commonly used to mimic the effects of Parkinson’s disease. Exposure of differentiated LUHMES cells to 6-OHDA resulted in proteolysis of p75NTR. Our preliminary analyses 3. Carter JS, Kearns AM, Weber RA, Reichel CM. also indicate that oxidative stress-induced cleavage of p75NTR Department of Biology, in dopaminergic cells does not require neurotrophins. Thus, ligand-independent stimulation of p75NTR proteolysis may Long term impact of acute stress on cognition, anxiety, and contribute to oxidative stress-associated degeneration of do- reinstated heroin seeking in male and female rats. paminergic neurons. Future studies will further elucidate the mechanisms through which p75NTR is activated by oxidative It has been suggested that withdrawal symptoms following stress, as well as evaluate the contributions of the receptor to substance use disorders (SUD) and post-traumatic stress disorder dopaminergic neurodegeneration. (PTSD) reciprocally exacerbate one another. Withdrawal symp-

6 toms, induced by cessation of substance abuse behavior, culmi- reward pathway, incentivizes certain behaviors and discourages nate as stressors and lead to persistent and compulsive relapse others by varying dopamine levels. Recently, a novel area known behavior. In addition, PTSD can be triggered by, and contrib- as the rostromedial tegmental nucleus (RMTg) was found to ute to, withdrawal-induced stress responses further increasing send a inhibitory GABAergic projection to the reward pathway. relapse potential. Previous work has shown that rats potentiate Therefore, the RMTg has been indicated as a potential “brake” substance-seeking behavior when exposed to scents associated mechanism for this well-researched circuit. Past research shows with restraint stress, a model used to mimic PTSD in rodents. that inactivation of the RMTg through Designer Receptors We examined the effects of restraint stress on heroin seeking and Exclusively Activated by Designer Drugs (DREADDs) increases anxiety related behaviors during withdrawal in male and female self-administration in rats in the presence of negative stimuli, rats. Rats in the stress group were restrained in a plastic tube indicating that the RMTg is necessary to process aversion. How- that did not allow for mobility with exposure to a scent (Group: ever, the DREADD mediating drug clozapine-n-oxide (CNO), Stress). Unstressed rats were exposed to the odor in a neutral when administered peripherally in non-DREADD animals, had cage with no restraint (Group: NoStress). All animals under- a similar effect, likely due to the production of its metabolite, went heroin self-administration (SA) and extinction followed clozapine. Also, data from our lab indicates that Sox2 gene by non-cued reinstatement testing with exposure to each scent. expression is highly concentrated within the RMTg, potentially During SA, active lever presses and intake (mg/kg) did not differ providing a new, more specific target for our research. Therefore, between stress groups, but females had higher intake than males. we hypothesized that the deactivation of the RMTg through On day 1 of extinction, females pressed the active lever more DREADDs and localized intracranial CNO injections will cause than males, without regard to stress group. For testing, the paired an increase in self-administration without the clozapine effects. odor (or a novel odor) was placed into the operant chamber We also predicted that activating the RMTg optogenetically and lever responding was recorded. NoStress male rats respond- (using a Cre-driven Sox2 promotoer) would result in conditioned ed above extinction values in response to paired and unpaired place avoidance (CPA) in a mice model. Sprague-Dawley rats scents indicating a lack of discrimination between odors. Stress were placed into a cocaine self-administration paradigm com- males differentiated between the odors by exhibiting the greatest bined with a progressive shock to determine if inactivation of the reinstatement responding to the paired odor. There were no dif- RMTg caused an increase in self-administration. Male Cre-Sox2 ferences in responding to odors for females. A subset of rats went mice were administered a channelrhodopsin viral vector into through an abstinence period before extinction, during which the RMTg and optical fibers were placed into the VTA. A CPA they experienced a battery of behavioral tests. Object recogni- paradigm was then used to determine if RMTg activation causes tion tests demonstrated that stressed males had a higher recog- avoidance of a aversive environment. Our results indicate that nition index relative to all other groups. On an elevated plus DREADD inactivation does cause an increase in shock toler- maze, stressed rats spent more time on the open arms than their ance in the cocaine self-administration paradigm. We also saw unstressed counterparts. Defensive burying trials showed that significant CPA in animals presumed to have correct injection stressed rats had a shorter latency to bury and spent more time sites and optical fiber placements. These results indicate that the burying a paired odor-contaminated dish than unstressed rats, RMTg plays a role in the inhibition of the dopaminergic circuit with males burying for more time than females. Future studies and could be used as a novel treatment target for human drug are necessary to examine the effects of heroin self-administration addicts. It also implicates Sox2 as a novel target for stimulation on behavior compared to rats taking saline. of the RMTg that can be used to increase specificity of future experiments.

4. Tomberlin JS, Pullmann D, Jhou TC, Vento PJ. Department of Psychology and Program of Neuroscience, College of Charleston; Department of Neurosciences, Concurrent Session I: Medical University of , Charleston, SC You have the option to attend: Investigating the Function of the Rostromedial Tegmental Nucleus (RMTg) through Optogenetic and Chemogenetic Oral Presentations for Molecular Neurobiology combined with Methodology. Drugs of Addiction. Room 4090 Learning is mediated through the dopaminergic mesolimbic pathway, which connects the ventral tegmental area (VTA) to Workshop with demonstrations for Back-Yard-Brains. cortical areas in the forebrain. This circuit, also known as the Room 3027

7 Poster Session I: Abstracts Molecular Neurobiology and Drugs of Addiction

1. Adonay Teklezghi, Karl T. Schmidt, Zoe McElligott. 21. Cunnane KA, Ferreira DW, Vazquez AA, Romero-Sandoval, UNC-Chapel Hill. EA. School of Medicine. Ethanol Withdrawal Affects Activity of Noradrenergic Genetic induction of CD163 in macrophages decreases Neurons. pain and inflammation and promotes wound healing.

3. Barboreck R, Combs K, Knick M, Halsell S. 23. Elder NH, El Bejjani R. . James Madison University. Engineering a Luminopsin Tool to Study the Identifying the Molecular Components of Caenorhabditis elegans Nervous System. Cold Nociception in Drosophila melanogaster. 25. Fisher C, Nazemi A, Kaur A. UNC Asheville. 5. Barman N, Siecinski SK, Morgenlander WR, Zhao C, Inducing Gene Expression of Major Urinary Proteins Corcoran D, Kwee LC, Arvai S, Gregory S. . (MUPs) in female mouse liver cell line Hepa1-6. The role of miR-149-5p in the T-cell mediated immune response of multiple sclerosis. 27. Gonzalez EN, Amat S, Christie JM. Max Planck Florida Institute. 7. Barnes CB, Wallace C, Jacobowitz BS, and Fordahl SC. Using Viral Vectors to Target Cell Types in The University of at Greensboro. the Cerebellum. The effect of dietary saturated vs. unsaturated fat on dopamine neurotransmission. 29. Greengrove EL, Dorn LE, McIntosh SE, Marshall SA. . 9. Beck K., McDonnell M. Wake Forest University. Increase in hippocampal microglia after non-dependent The effect of BaCl2 on the resting membrane potential ethanol binge. of the superior flexor muscle of crayfish, Procambarus clarkia. 31. Guerrero R, Brown Q, El Bejjani R. Davidson College. A novel role for Notch in mechanosensory neuron 11. Bland KM, Casey ZO, Handwerk CJ, Holley ZL, Vidal GS. connectivity in C. elegans. James Madison University. Exploring a role for integrin beta 3 in dendritic spine 33. Imam ER, Wu S, Flinchum KA, Page GE, Buckthought A. pruning in cerebral cortex. Roanoke College. Combination of cues in 3D vision: Interaction between 13. Bolton PG, Arjune K, Phillips T, Zarubin V, Mickley binocular rivalry and motion parallax. Steinmetz KR. . Examining the N1, an event-related potential (ERP) 35. Isabella R Grifasi, Scot E McIntosh, S. Alex Marshall. waveform, and cortisol responses to motivational stimuli: High Point University. A pilot study. Alterations in glial activation following binge-like ethanol consumption. 15. Burgos Aguilar C, Ferris MJ, Sexton LL, Childers SR, Xiao R, Howlett AC. Wake Forest University. 37. Jackson TB, Chao YS, Eid M, Pullman D, Jhou TC. mGluR2/3 Agonist LY379268 on G protein activation College of Charleston; Medical University of South Carolina. and CREB phosphorylation. Examining the role of serotonin agonism at the rostromedial tegmental nucleus towards behaviors of 17. Carpenter M, Awalt K, Mans K, Mans R. cocaine-averse rats. Southern University. Behavior and Biochemical Aspects of Learning and 39. Jones T, Lom B. Davidson College. Memory in Danio rerio. Early Developmental, Low-Dose BPA Exposure does not Significantly Impact Zebrafish Locomotor Activity. 19. Carter JS, Kearns AM, Weber RA, Reichel CM. College of Charleston. 41. Kasiah J, Suess GJ, Williams BF, Chassiang B, Frantz KJ. Long term impact of acute stress on cognition, anxiety, Georgia State University. and reinstated heroin seeking in male and female rats. Influence of Antibiotic Cocktail on Gut Microbiota in Adolescent and Adult Male Rats.

8 43. Lakhani A, Lom B. Davidson College. 63. Shook EN, Kuchera M. Davidson College. Slitrk1 Knockdown Reduces Rohon-Beard Neurons in Exploring brain-like representations in recurrent neural the Developing Zebrafish Spinal Cord. networks trained on a spatial navigation task.

45. Lawlor M, Nowling D, Cowen M, Ghate P, and Lizarraga 65. Smith KA, Saunders CJ, Silver WL. Wake Forest University. SB. University of South Carolina. How to Irritate an Earthworm: A molecular Investigation Cellular mechanisms associated with RAB3GAP1 into the presence of TRP channels in E. hortensis. dysregulation and relevance to Warburg Microsyndrome pathology. 67. Tomberlin JS, Pullmann D, Jhou TC, Vento PJ. College of Charleston; Medical University of South Carolina. 47. Mans RA, Payne CH and Hinton KD. Investigating the Function of the Rostromedial Georgia Southern University - Armstrong Campus. Tegmental Nucleus (RMTg) through Optogenetic Ex vivo activation of cholinergic receptors inhibits GSK- and Chemogenetic Methodology. 3β in the telencephalon of adult zebrafish (Danio rerio). 69. Wallace CW, Barnes CN, Jacobowitz BS, Fordahl SC. 49. Mcfaddin JA, Siemsen BM, McGinty JF. University of North Carolina at Greensboro. College of Charleston; Medical University of South Carolina. Enduring effects of saturated fat on dopamine The effect of chemogenetic activation of prelimbic corti- neurotransmission are not reversed by replacement cal neurons projecting to the nucleus accumbens core on with omega-3-rich flaxseed oil. relapse to cocaine-seeking. 71. Woodlief K, Odom JH, Coller M, Newman AH, Nader 51. Megan Andres, Savannah Moore, Cory Duckworth, Natalie MA. Wake Forest School of Medicine. Macy, Vy Tran, Ryan A. Shanks Ph.D., Steven A. Lloyd The effects of dopamine D3R partial agonists and antago- Ph.D. University of North Georgia. nists on drug seeking, cognition, and analgesia in female Effects of adolescent prescription stimulants and stress cynomolgus monkeys self-administering oxycodone. on adult addiction susceptibility. 73. Colbert, S and Ackerman KM. High Point University. 53. Moore NS, Mans KB. Effects of Nicotine on Zebrafish Retinal Development. Georgia Southern University - Armstrong Campus “Light” Sleeping: The Effects of Chronic Sleep 75. Zhang J, Rife TK. James Madison University. Deprivation on Zebrafish Brain Biochemistry Using Dual Luminescense-Based Reporter Gene Assay: Luciferase and beta-Galactosidase to explore the func- 55. Owens HG, Driscoll GJ, Collazo A, Birgbauer E. tions of tau and alpha-synuclein. . Examining the role of Lysophosphatidic Acid as a Potential Axon Guidance Molecule in the Chicken Visual System.

57. Sammons KM, Okafor ZC, Cleland CL. James Madison University. Contributions of Aδ Nociceptors to the Nociceptive Withdrawal Response in Intact Unanesthetized Rats. Concurrent Session II:

59. Savage JT, Baldwin KT, Eroglu C. You have the option to attend: Duke University Medical Center. What is the role of PTPRZ1 in astrocyte development? Oral Presentations for Cognition/Behavior combined with Injury/Repair. 61. Schein H, Mans KA. Armstrong Campus. Room 4089 The effects of vibration stress on zebrafish brain biochemistry. Workshop with demonstrations for Back-Yard-Brains. Room 3027

9 Poster Session II: Abstracts Cognition/Behavior and Injury/Repair

2. Abiodun S, Addicott M. Duke University. The Effects of Transcranial Magnetic Stimulation 24. Dorn AY, Underly RG, Moharty S, Bhat NR, Shih AY. on Insula-Based Functional Connectivity. College of Charleston; Medical University of South Carolina. The Developmental Impact of DDAH1 in Mural Cells. 4. Adams CV, Triblehorn J, Gudz T, Novgorodov S. College of Charleston; Medical University of South Carolina. 26. Duryee ML, Zens, MM, Sparrock L, Franssen RA, Franssen, Molecular mechanisms of mitochondrial dysfunction in CL. Longwood University. regulated necrotic cell death: Implications for stroke and The Trials and Triumphs of a New Interdisciplinary traumatic brain injury. Neuroscience Studies Minor.

6. Allison Usry. . 28. Eagle AK, Lever LC, Franssen CL. Longwood University. Factors influencing age of first sexual encounter. Spit Happens! Salivary Cortisol Responses of Wilderness Therapy Clients as an Efficacy Measure. 8. Bagnell AM, Cheon S, Lizarraga SB. University of South Carolina-Columbia. 30. Eceiza A, Lahue C, Kaur A. UNC Asheville. Characterizing the Impact of the Gene ASH1L in the Cloning Vomeronasal Type-2 Receptors for Expression Regulation of Neuronal Gene Expression. and Analysis in a Cell Culture Model System.

10. Barhorst KA, Belanger KH, Doyle H, Ghosh A, Ramirez JJ. 32. Eppley KJ, Faust-Casey BK, Goodman JI, Gosine AE, Bruce Davidson College. AA, Wilhelm JC. College of Charleston. The effects of cholinergic degeneration on septal Effects of Estrogen on Sensory Neuron Participation in facilitation of long-term potentiation in the perforant Axon Regeneration Following Peripheral Nerve Injury. path in rats. 34. Fruchterman TC, Elliot CN, Sparrock LS, Franssen RA. 12. Beck ME, Borckart JJ, Carpenter LA, Gwynette MF, Joseph Longwood University. JE, Lester S, Lohnes L. College of Charleston; The Medical Individual variation in maternal response tied to University of South Carolina. differential expression of oxytocin and estrogen in Learning Enhancement through Neurostimulation several brain regions. (LENS): The Effect of Transcranial Direct Current Stimulation (tDCS) and Social Training in Autistic 36. Gaudin VA, Cleland CL. James Madison University. Spectrum Disorder. Escape responses from looming stimuli in Phidippus audax. 14. Benz I and Grider MH. High Point University. ISRIB as a Potential Therapeutic Drug for 38. Hathaway S., Cely C., Mulloy S., Tibbetts E., Fahrbach S. Neuronal Injury. Wake Forest University. Impact of social experience on synaptic density in the 16. Bodner KA, Riley MP, Hochschuler JL, Gendle MH. mushroom bodies of the paper wasp Polistes fuscatus. . Potential cognitive-enhancing effects of oral 40. Hudson, J.B., Schmidt, K.T., McElligott, Z.A. phosphatidylserine in middle-age adults. UNC-Chapel Hill. An inexpensive and customizable system for measuring 18. Brown, TA. Ferrum College. consummatory behaviors in mice. Coping Skills in Freshmen Versus Seniors. 42. Jesse Meagher, He Zheng. Max Planck Florida Institute. 20. Crisp A, Thompson SG, Godwin K. . Cellular Activity in the Primary Somatosensory Cortex Hemispheric Lateralization in Pun Processing. Underlying Animal’s Perception and Decision-Making.

22. Doddapaneni D, Asede D, Bolton MM. Max Planck 44. Leung K, Peterson S, Benowitz L. Davidson College. Florida Institute for Neuroscience. The Role of Complement in Retinal Ganglion Cell Properties of neurons in the anterior intercalated Survival and Regeneration after Optic Nerve Crush. cell cluster.

10 46. Mavi S, Pegelow M, Wentzel M, Cleland C. 66. Thomas MD, Gaudin VA, Cleland CL. James Madison University. James Madison University. The effect of noxious stimulation on the nociceptive tail Escape Behavior of the Grammostola rosea Tarantula and foot withdrawal response in unrestrained rats. and Phidippus regius Jumping Spider in Response to Heat Stimuli. 48. McElwain VJ, Borckardt J, Carpenter L, Gwynette F, Lester S, Lohnes L, Joseph J. College of Charleston; 68. Wagner SW. Georgia Southern University. Medical University of South Carolina. Developing Sensory Behavioral Assays for Zebrafish The Effect of Combination Therapies on Task switching Autism Model. in Autistic Adolescents. 70. Waugh, C. Escobedo, C. Kalantar, A. Ford, B. Kraemer, B. 50. Meghan Pavelka, Samantha Everett, Zoe Kaplan, Sarah Eastern Kentucky University. Snouse, Charles Fennell, Leslie Sargent Jones, and Mark C. Activation of the p75 neurotrophin receptor in Zrull. Appalachian State University. degenerating dopaminergic neurons subjected to The IMPULSE neuroscience journal: an educational tool oxidative stress. for undergraduates of all disciplines. 72. Webb, LC, Grider M. High Point University. 52. Miranda Dougherty. Ferrum College. Neuroprotection Following Injury: The Role of Stress In Season and Out of Season. Integrated Stress Response Inhibitor (ISRIB).

54. Moseley SM, Powell PG, Howell SM, Zial EA. 74. Muhr J, Gentry M. and Ackerman KM. James Madison University. High Point University. Male Physiological Response to Female Voices During Establishing a Damage Paradigm to Examine Retinal High and Low Fertility. Neuron Regeneration at a PUI.

56. O’Connor SA, Ross TP. College of Charleston. 76. Zeher AM, Cleland CL. James Madison University. The Role of Executive Functions in Verbal Fluency: An Antennae pointing and the escape response in the cricket Examination of the Controlled Oral Word Association Test. Acheta domesticus.

58. Patrick DeZego, Eileen Reed, Sam Kim, Abby Anderson, Glen McKinney, Christina Benedict, Emily Adams, Sophie Gonzalez, John Lewis, Tommy Noonan, Cecil Saunders, Wayne Silver. Wake Forest University. The sixth sense and the earthworm, Eisenia Hortensis.

60. Roig JR, Torregrossa LJ, Park S. . Bodily self disturbances as a specific predictor for schizophrenia.

62. Sprouse A and Grider MH. High Point University. Relative contributions of apoptosis and necrosis in PC12 stroke model.

64. Stefanowska-Cieslak M, Driscoll G, Birgbauer E. Winthrop University. Investigating Semaphorin 3A as a Possible Repulsive Axon Guidance Molecule in the Chick Visual System.

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Oak HOllOw Center 41 The Aldridge VillAge 41 55 40 45 46 43 44

42 HPU EstatE and RoPEs CoURsE

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