Annual Report 2020 for Karolinska

Total Page:16

File Type:pdf, Size:1020Kb

Annual Report 2020 for Karolinska K 2021–2519 Annual report 2020 Introduction ........................................................................................................................................ 4 COVID-19 ............................................................................................................................................ 4 Vision and long-term strategies ......................................................................................................... 5 Organisation ....................................................................................................................................... 5 Karolinska Comprehensive Cancer Center ..................................................................................... 5 Board of Directors .......................................................................................................................... 6 The Cancer Theme .......................................................................................................................... 7 Management structure of the Cancer Theme ................................................................................ 7 Cancer Research KI ......................................................................................................................... 7 National and international networks ................................................................................................. 8 Care ................................................................................................................................................ 8 Education ........................................................................................................................................ 8 Research ......................................................................................................................................... 9 Key events during the year ................................................................................................................. 9 Care production and accessibility .................................................................................................... 10 Outcome data for the Cancer Theme’s activities 2018–2020 ...................................................... 11 First visit ....................................................................................................................................... 11 Standardized care pathway .......................................................................................................... 11 Surgeries ....................................................................................................................................... 13 Human Resources ............................................................................................................................. 13 Employees .................................................................................................................................... 13 Mentorship program ................................................................................................................ 14 Quality report ................................................................................................................................... 14 Quality management system ....................................................................................................... 14 Quality follow-up .......................................................................................................................... 14 Personalized care, follow-up of the experience of received care ................................................ 15 Patient satisfaction ................................................................................................................... 15 Nursing – Nutrition, pressure ulcers and falls .............................................................................. 15 Nutrition ................................................................................................................................... 15 Pressure ulcers ......................................................................................................................... 16 Fall ............................................................................................................................................ 16 Healthcare related infections and hygiene .................................................................................. 16 Healthcare related infections ................................................................................................... 16 Basic hygiene and clothing rules .............................................................................................. 17 Multiresistant bacteria ............................................................................................................. 17 1 Patient safety................................................................................................................................ 18 Environment ................................................................................................................................. 18 Business development ..................................................................................................................... 19 Green Cross .................................................................................................................................. 19 The work of the multidisciplinary team ....................................................................................... 20 Patient involvement ..................................................................................................................... 20 Palliative care ............................................................................................................................... 20 Contact nurses .............................................................................................................................. 20 My Care Plan ................................................................................................................................ 21 Cancer rehabilitation .................................................................................................................... 21 My Code ....................................................................................................................................... 21 Research, education and development............................................................................................ 22 Scientific Advisory Board .............................................................................................................. 22 Science for Life Laboratory ........................................................................................................... 22 Scientific production and technology development ................................................................ 23 Data driven Life Science initiative ............................................................................................ 23 Health Care ............................................................................................................................... 23 Test beds and tools for validating and implementing new technologies ................................ 23 Preclinical and translational research .......................................................................................... 24 Cancer papers from KI 2020 ..................................................................................................... 26 Caring sciences ......................................................................................................................... 27 Department of Breast cancer, Endocrine tumours and Sarcoma ............................................ 28 Breast cancer ........................................................................................................................ 28 Endocrine tumours ............................................................................................................... 29 Sarcomas .............................................................................................................................. 29 Department of Cell therapy and Allogeneic stem cell transplant ............................................ 29 Department of Haematology ................................................................................................... 30 Myeloma ............................................................................................................................... 30 Myeloid malignancies ........................................................................................................... 30 Lymphoma ............................................................................................................................ 30 Department of Head, Neck, Lung and Skin cancer ................................................................... 30 Head and neck cancer .......................................................................................................... 30 Lung cancer........................................................................................................................... 31 Melanoma ............................................................................................................................ 32 Department of Pelvic cancer ...................................................................................................
Recommended publications
  • Karolinska Inatitutet) Stockholm, Sweden
    NO. IAEA-H-764-F • ' •/•••', TITLE I. '- Experimental Investigations on; the Interplay between natural and artificial radiation protection FINAL REPORT FOR THE PERIOD 1 .July; 1969; - 3OvJune 0.972 ' AIJTHOH(S) • !. L.Révésis INSTITUTE Dept. cf Tumor Biology Karolinslra Institutet (inst. Fiir TumiSrbiologi Karolinska Inatitutet) Stockholm, Sweden -#" IHTERMTIOML ATOMIC ACEWCY lÉMÉÍffiafeÉ^ i - INST. FOR TUMORBIOLOGI KAROUNSKAINSTITUTET m 10401 STOCKHOLM 60 DEPT. OF TUMOR BIOLOGY KAROLINSKA INSTÍ.TUTET S-104 01 STOCKHOLM 60 SWEDEN . CERTIFIED FINAL REPORT Research Contract Ho.: 764 Title of Research Project: Experimental investigations o'n the interplay between natural and artificial radiation protection. Institute where research is being carried out: Department of Tumor Biology» Royal Karolinska Institute Medical School, Stockholm, Sweden. Principal scientific investigator: László Révész, H.D., Professor. Time period covered: 1 July 1969 - 30 June 1972. The experimental investigations, carried put during the timé period covered by the original contract and the subsequent renewal contracts, closely followed the program outlined in our original grant application of 1968 and the comple- mentary plans indicated in the"subsequent renewal applications. The work carried out, the results obtained and:.the conclusions drawn are described in details in the publications which are listed in;this report (vide infra) and of which copies have been submitted to the Agency. The work can be summarized in the following.: . :::' í '::.,~>: "-r^-••'••'•'
    [Show full text]
  • Annual Report 2002 Contents
    Annual Report 2002 Contents 1 The year in brief 2 Akademiska Hus, summary 3Vision, business concept, success factors and objectives 4 Statement by the President 7 THE MARKET 8 Market shares 10 Higher education and research 12 PROPERTY OPERATIONS 12 Akademiska Hus property operations 16 Akademiska Hus i Lund AB 18 Akademiska Hus i Göteborg AB 22 Akademiska Hus i Linköping AB 24 Akademiska Hus i Stockholm AB 28 Akademiska Hus i Uppsala AB 30 Akademiska Hus i Norr AB 32 CONSTRUCTION PROJECTS 32 Projects 34 Awards for completed projects 34 Design Centre, Lund 36 Department of Nursing and the Neurotec Department, Huddinge 36 The Konradsberg Campus 38 The future 41 Sensitivity and risk analysis 42 Five-year summary 44 Financing 48 Environmental Report 52 Organisation and employees 53 The board’s mission 54 Board 55 Executive management 57 Definitions 58 Summary of results 59 Income statements 60 Balance sheets 62 Cash flow statements 63 Notes with accounting and evaluation principles 72 Audit report 73 Addresses The Administration Report comprises pages 2–3, 7, 12–15, 32–33 and 38–46. The year in brief Akademiska Hus is a leader in the development of higher At the year-end a number of construction projects were in education environments and offers universities and col- progress, the largest of which were the Institute of Educa- leges attractive study and research environments. The com- tion in Stockholm, the refurbishment of the Biomedical pany has approximately 80 per cent of the education and Centre in Uppsala and redevelopment and new construction research premises market at university locations and at the Karolinska Institute in Huddinge.
    [Show full text]
  • Clinical and MRI Features of Cerebral Small-Vessel Disease in Type 1
    Diabetes Care 1 Clinical and MRI Features of Lena M. Thorn,1–3 Sara Shams,4 Daniel Gordin,1–3,5 Ron Liebkind,6 Cerebral Small-Vessel Disease in Carol Forsblom,1–3 Paula Summanen,1–3,7 Stefanie Hagg-Holmberg,¨ 1–3 Type 1 Diabetes Turgut Tatlisumak,6,8,9 Oili Salonen,10 Jukka Putaala,6 Juha Martola,4,10 and 1–3,11 https://doi.org/10.2337/dc18-1302 Per-Henrik Groop, on behalf of the FinnDiane Study Group OBJECTIVE To assess the prevalence of cerebral small-vessel disease (SVD) in subjects with type 1 diabetes compared with healthy control subjects and to characterize the diabetes-related factors associated with SVD. RESEARCH DESIGN AND METHODS This substudy was cross-sectional in design and included 191 participants with type 1 diabetes and median age 40.0 years (interquartile range 33.0–45.1) and 30 1Folkhalsan¨ Institute of Genetics, Folkhalsan¨ Re- healthy age- and sex-matched control subjects. All participants underwent search Center, Helsinki, Finland clinical investigation and brain MRIs, assessed for cerebral SVD. 2Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, RESULTS Helsinki, Finland 3 Cerebral SVD was more common in participants with type 1 diabetes than in Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland healthy control subjects: any marker 35 vs. 10% (P = 0.005), cerebral microbleeds 4Department of Radiology, Karolinska University (CMBs) 24 vs. 3.3% (P = 0.008), white matter hyperintensities 17 vs. 6.7% (P = Hospital, and Department of Clinical Neurosci- 0.182), and lacunes 2.1 vs.
    [Show full text]
  • Veterinary & Agricultural Sciences
    Veterinary & Agricultural Sciences Postgraduate Opportunities 2019 Influencing the world since 1583 The University of Edinburgh Veterinary & Agricultural Sciences Postgraduate Opportunities 2019 01 02 Introduction “ Edinburgh isn’t so much a city, more 04 Online learning masters programmes a way of life … I doubt I’ll ever tire of 15 Postgraduate professional development 16 On-campus taught masters and masters by research programmes exploring Edinburgh, on foot or in print.” 21 A world-class research experience Ian Rankin 22 Research opportunities Best-selling author and alumnus 26 About the Royal (Dick) School of Veterinary Studies 27 Our ethos 28 Graduate School 29 Community 30 Research and teaching environment 31 Facilities 32 Employability and graduate attributes 34 Applications and fees 36 Funding 38 Campus maps 40 Get in touch www.ed.ac.uk/medicine-vet-medicine/postgraduate The University of Edinburgh 02 Veterinary & Agricultural Sciences Postgraduate Opportunities 2019 03 For more than 400 years the University of Influencing the Edinburgh has been changing the world. Our TOP 50 staff and students have explored space, won We’re consistently ranked one of Nobel Prizes and revolutionised surgery. They’ve published era-defining books, run the country, the top 50 universities in the world. world since 1583 th made life-saving breakthroughs and laid the We’re 18 in the 2019 QS World foundations to solve the mysteries of the universe. University Rankings. Our distinguished alumni include NASA astronaut TH Piers Sellers, former MI5 Director-General Dame 4 Stella Rimington, Olympians Sir Chris Hoy and We’re ranked fourth in the UK for 14 Nov 2018 Katherine Grainger and historical greats such research power, based on the 2014 Postgraduate Open Day as philosopher David Hume, suffragist Chrystal Research Excellence Framework.* Macmillan, who founded the Women’s International www.ed.ac.uk/ postgraduate-open-day League for Peace and Freedom, and physicist and mathematician James Clerk Maxwell.
    [Show full text]
  • Nordic Brain Network (NBN)
    Kivipelto_NBN_Projects Prof. Miia Kivipelto has broad national, Nordic, and international collaborations, she is PI and/or co-investigator in several international collaborative projects: (role in projects as Principal Investigator (PI) or Co-investigator marked). • Nordic Brain Network (NBN): (PI: Miia Kivipelto) Professor Kivipelto and her team have recently established the ‘Nordic Brain Network’, which has increased the resources available to the field of cognitive impairment, dementia/Alzheimer’s disease and aging research and promoted collaboration among Nordic countries, with its members primarily working in Sweden and Finland. NBN is affiliated with two centers of Excellence at KI, Dept of NVS (Aging Research center and Center of Alzheimer Research), and University of Finland and National Institute for Health and Welfare in Helsinki, Finland. Memory clinics from Stockholm (Karolinska University Hospital) and from Kuopio are also involved. The NBN also collaborates with several other universities in Nordic countries and numerous international researchers from various regions in the world. http://www.nordicbrainnetwork.com/?page_id=205. Epidemiological Research • Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study (PI: Miia Kivipelto, main collaborators: Prof. Hilkka Soininen (Dept. Neurology, Univ. of Kuopio), Prof. Jaakko Tuomilehto and Prof. Tiina Laatikainen (National Institute of Health and Welfare, Helsinki) and The Aging Research Center (ARC), KI, Stockholm. The CAIDE study investigates lifestyle and cardiovascular risk factors for dementia, Alzheimer’s disease (AD) and structural brain changes using the follow-up period extending up to almost 30 years. • Kungsholmen Project (KP) and SNACK (two large population based studies) (Co- investigator: Miia Kivipelto). Close collaboration with the researchers in charge of the database: Professors Laura Fratiglioni and Bengt Winblad.
    [Show full text]
  • Paolo Parini, MD, Phd – Curriculum Vitae
    1 1 Paolo Parini, MD, PhD – Curriculum Vitae 2 3 4 - Date of birth: July 20, 1964 Personnr.: 640720-5738 5 - Place of birth: Rimini, Italy 6 - Citizenship: Italian, Swedish 7 - Addresses: Karlbergsv. 41 Dept. of Laboratory Medicine, C1 74 8 S-113 37 Stockholm Karolisnka University Hospital Huddinge 9 Sweden SE-141 86 Huddinge 10 +46 (0)834 79 75 Sweden 11 Mobile: +46 (0)70 456 21 92 Tel. +46 (0)8 58589310¸ Fax +46 (0)8 58581260 12 - E-mail: [email protected], 13 - Languages: Italian, English, and Swedish. 14 15 Education and Degrees 16 17 - Karolinska Institutet, Stockholm, Sweden. Professor in Clinical Chemistry. 2012. 18 - Karolinska Institutet, Stockholm, Sweden. Associate Professor. 2007. 19 - Karolinska Institutet, Stockholm, Sweden. Philosophy Doctor in Internal Medicine. 1994-1999. 20 - University of Bologna, Italy. School of Specialization in “Gastroenterology and digestive Endoscopy” 21 Specialist (final evaluation: 70/70 cum laude), 1990-1994. 22 - University of Bologna, Italy. Medical Doctor (final evaluation: 110/110 cum laude), 1983-1990. 23 - Scientific High School “A. Einstein”; Rimini, Italy. Graduated (final evaluation: 56/60), 1978-1983. 24 25 Present Position 26 27 28 - Director of Research, Education, Development and Innovation, at the Inflammation and Infection Theme, 29 Karolinska University Hospital, Stockholm, Sweden 30 - Professor in Clinical Chemistry at the Department of Medicine and at the Department of Laboratory Medicine, 31 Karolinska Institutet, Stockholm, Sweden 32 - Senior Consultant at the Patient Area Endocrinology and Nephrology, Inflammation and Infection Theme, 33 Karolinska University Hospital, Stockholm, Sweden 34 - Visiting Professor, Department of Pharmacological and Biomolecular Sciences, University of Milano 35 36 Post-doctoral activities 37 - Oct.
    [Show full text]
  • Karolinska Institutet, Core Facility SMILE (Stockholm Medical Image Laboratory and Education)
    Karolinska Institutet, Core facility SMILE (Stockholm Medical Image Laboratory and Education) http://smile.ki.se/ - New user registration guide - List of available educational Courses for SMILE Users - Further educational resources - Introduction to facility and services Facility Manager: Scientific Director: Andy Triantafyllos Paparountas Ph.D., MBA Professor Birgitta Janerot Sjöberg CLINTEC CLINTEC email: [email protected] phone: 08-524 83801 Address: SMILE, Karolinska University Hospital Huddinge, Medical Radiation Physics and Nuclear Medicine C2-76, 141 85 Stockholm New User registration Application + Free online courses 1. a: SMILE new user registration b: SMILE new user Computing Rules Circular 2. Only For non-KI academic users: KI affiliate account required! 3. Register in the KI invoicing system iLab (free online courses can be requested through this platform ) iLab invoicing system help connection details will be provided at the iLab registered email Andy Paparountas, Karolinska Institute Core Facility SMILE 28/08/2020 3 http://smile.ki.se/ NVIDIA Online courses (page 1 of 2) free for SMILE Core Facility Users upon registering on iLab as SMILE’s users -students (BSc, MSc, PhD) only need to register on iLab as users to access the courses to access the GPU-Server for hands-on training addition of Project_ID in iLab is required contact your supervisor -post docs and employees need to register on iLab as users and register 1 or more chargeable Project_ID in iLab access to both NVIDIA courses + GPU Server (-prerequisites
    [Show full text]
  • Anna Hägg Translating Swedish University Webpages Into English
    Estetisk-filosofiska fakulteten Anna Hägg Translating Swedish University Webpages into English A study of translation strategies Engelska C-uppsats Termin: Vårterminen 2011 Handledare: Elisabeth Wennö Karlstads universitet 651 88 Karlstad Tfn 054-700 10 00 Fax 054-700 14 60 [email protected] www.kau.se Abstract Titel: Translating Swedish University Webpages into English. A study of translation strategies. Författare: Anna Hägg Antal sidor: 31 Abstract: The focus of this paper is on university webpages and the translation of these. With the help of existing translation strategies, it aims to map out the strategies used in Swedish webpages in English with a focus on names and words/expressions for which there are no direct equivalents in English. The study shows that the most common strategies regarding the translation of names were translating word for word and using the nearest equivalent. Regarding language-specific expressions, the most common strategies were using cultural equivalents and reduction. Not surprisingly, additions in the text were most often matters of importance to an international audience, and the most common omissions were matters that only had a local interest. Nyckelord: University webpages, translation, translation strategies, Swedish, English Table of Contents 1. Introduction and aims ...................................................................................................... 1 1.1. Introduction .............................................................................................................
    [Show full text]
  • Departments of Pediatrics, Uppsala University, and Pediatric Radiology,, Karolinska Institutet, S
    J.P. chanoinex, J.J. ~ody~,G. Van Vliet, F. Delange. Depts. of Pediatrics and Radioisotopes, St Pierre Hos- Departments of Pediatrics, Uppsala pital, Dept.of Medicine, Inst. J Bordet, Children Hos- University, and Pediatric Radiology,, 23 pital,. Free University of Brussels, Belgium. 26 Karolinska Institutet, S: t Garan's MONOMERIC CALCITONIN (CT) DEFICIENCY IN PATIENTS WITH Children's Hospital, Stockholm, Sweden. CONGENITAL NON GOITROUS HYPOTHYROIDISM (CH) DURING METHODS FOR BONE MATURITY ASSESSMENT TO EARLY INFANCY. EVALUATE PRENATAC HYPOTHYROIDISM. CT deficiency has been reported in children and adolescents with Delayed skeletal maturation in newborn infants wit Cll;bbt whether it is also deficient in CH patients during infancy congenital hypothyroidism (CH) is considered t has not been investigated. Plasma extraction of CT has much impro- reflect the degree of intrauterine hormone deficien ved the sensitivity and specificity of CT radioimmunoassays for cy. Bone development was assessed by X-ray during th the measurement of the monomeric CT form, the active form of this flrst month of life in 63 infants who had positiv hypocalcemic hormone. To further analyze CT secretion in early in- screening tests for CH. Serum hormone analysis con fancy, we measured CT and Calcium (Cn) values in I) normal infants firmed the diagnosis in 46 infants while the remainin aged 0-2 yrs (gr. NL-I, n=39) and 2-5 yrs (gr. NL-2, n=12) and 2) 17 infants were euthyroid at follow-up. Therapy wa CH infants aged 0-2 yrs (gr. CH-I, n=6) and 2-5 yrs (gr. CH-2,114) initiated in CH patients at the same age as radiogram Results are shown in the table (Mean !: SEM):( XX pC0,OI as compa- were taken: 14.5i5.7 (x*SD) vs 15.0'5.5 days.
    [Show full text]
  • Stockholm Academic Forum (Staf)
    100.000 Stockholm Academic Forum (Staf) is the Staf is run by Higher education Higher education Students come peak collaborative body and collective CEO Maria students in staff and faculty from 70 + voice of the City of Stockholm and its 18 Fogelström Stockholm: in Stockholm: countries universities and higher education institutions. Kylberg 100.000 20.400 OUR MEMBERS Stockholm School KTH Stockholm University Karolinska Institute Konstfack Södertörn University of Economics Royal Institute of www.su.se www.ki.se University of Arts, www.sh.se www.hhs.se Technology Crafts and Design www.kth.se www.konstfack.se P Sophiahemmet Stockholm School Beckmans College Royal Institute The Royal College Stockholm University of Theology of Design of Art of Music University of the Arts www.shh.se www.ths.se www.beckmans.se www.uniarts.se www.kmh.se www.kkh.se Swedish Defence Ersta Sköndal Bräcke The Swedish The Swedish School University College of The Erica University University College Red Cross of Sport and Health Music Education Foundation www.fhs.se www.esh.se University College Sciences, GIH www.smi.se www.ericastiftelsen.se www.rkh.se www.gih.se OUR MISSION OUR BRANDS • To strengthen Stockholm’s position as a leading academic destination in Sweden and abroad • To support the role of academia in society. www.staforum.se www.sdcn.se www.studyinstockholm.se Social Responsibility Staf is committed to offering all people equal opportunities and support Equality their ability to realize their full potential. In order to combat discrimination, In Stockholm, 10 out of 18 university we strive to carry out work that is free from all forms of prejudice and as a deans are women.
    [Show full text]
  • –Strategic Research Networks- Research Report JSPS Core-To-Core Program FY2013
    (様式7) 別紙3 FY2013 JSPS Core-to-Core Program –Strategic Research Networks- Research Report Project No. 22002 Research Theme Cooperative international framework in TGF-b family signaling Duration of Project April 1st, 2010 - March 31st, 2015 ( 60 months) Core Institution in Japan University of Tokyo, Graduate School of Medicine Implementing Organizations Country Japan Core Institution The University of Tokyo, Graduate School of Co-Chair (name and title) Kohei MIYAZONO (Professor) Number of Cooperating Institutions 6 University of Tsukuba Yamanashi University University of Toyama Cooperating Institutions Showa Pharmaceutical University Tokyo University of Pharmacy and Life Sciences Ehime University Country Sweden Core Institution Uppsala University, Ludwig Cancer Institute Co-Chair (name and title) Carl-HENRIK HELDIN (Director) Number of Cooperating Institutions 4 Karolinska Institute Umeå University Cooperating Institutions Lund University The University of Gothenburg Matching Fund Funding from Ludwig Institute for Cancer Research Country the Netherlands Core Institution Leiden University Medical Center Co-Chair (name and title) Peter TEN DIJKE (Professor) Number of Cooperating Institutions 0 Cooperating Institutions Matching Fund Country Core Institution Co-Chair (name and title) Number of Cooperating Institutions Cooperating Institutions Matching Fund 1 (様式7) 別紙3 Result of Program Implementation Before we started this JSPS core-to-core program, we had exchanged some senior and young researcher between Japan and Sweden/Netherlands in order to conduct the collaborative research projects. We also had TGF-β meetings in Sweden and the Netherlands at which only a limited number of students were able to participate from Japan. However, since we started this program, the number of exchanged researchers between Japan and Sweden/Netherlands significantly increased, which greatly helped conducting the collaborative research projects.
    [Show full text]
  • ISOMA 2019 International Symposium of Military Academies May 20TH-23RD
    Welcome to Military Academy Karlberg ISOMA 2019 International Symposium of Military Academies May 20TH-23RD Page 1 ISOMA 2019 - Stockholm Welcome! It is an honor to welcome you all to The Swedish Mi- litary Academy Karlberg, together with The Swedish Defence University, and the 6th International Symposium of Military Academies, ISOMA (formerly ISoDoMA). ISOMA works within the framework of the International Association of Military Academies, IAMA, whose mission is to promote knowledge and competency sharing in the field of education between member military academies. The last time the Symposium took place was in Canada in 2017 and the Royal Military College Sa- int-Jean was the organizer for that fifth symposium. The lectures and the discussions gave us all fresh knowledge and ideas to develop our officer training. Our world is currently facing several tough chal- lenges and much uncertainty. We have to adapt and follow the trends in our armed forces, and this certainly applies to the training for the next generation of officers. Therefore the main theme this year is Managing adaptation in military education and training. I strongly believe that the ISOMA symposiums will play an important role in fulfilling our educational mission. Since 1792 when the academy first started, the name ’Karlberg’ has been associated with education and training of officers; it is the oldest military academy in the world that is still housed in its original buildings with an unbroken chain of education. I hope that your stay here at Karlberg will stimulate new knowledge & ideas, and give you the opportunity to learn from each other, share experiences and establish future collaboration by meeting colleagues from around the world.
    [Show full text]