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Power List 2018 APRIL 2018 # 40 Editorial Upfront In My View Sitting Down With Stop and look at how far Preparing for the EU’s new What can algae teach us Sophie Kornowski-Bonnet, the industry has come data protection regulation about medicine design? Roche Partnering 09 10 – 11 20 – 21 50 – 51 100 Power List 2018 www.themedicinemaker.com Continuous Growth Fibra-Cel® disks—3-D growth matrix for perfusion and continuous processes Suspend your disbelief: > Less susceptible to shear forces, The three-dimensional Fibra-Cel matrix clogging, and fouling entraps anchorage dependent and > Ideal for secreted product and vaccine suspension cells—for optimized growth production conditions and increased yields. > Suitable for GMP production > For use in autoclavable, sterilize-in- place or BioBLU® Single-Use Vessels www.eppendorf.com/Fibra-Cel Fibra-Cel® is a registered trademark owned by Imerys Minerals California, Inc., USA and licensed to Eppendorf, Inc., USA. Eppendorf®, the Eppendorf Brand Design and BioBLU® are registered trademarks of Eppendorf AG, Germany. All rights reserved, including graphics and images. Copyright © 2018 by Eppendorf AG. tmm_epp_ad_210x266_2018_04.indd 1 28.03.18 13:34 Online this Month The Power List The 2018 Power List, starting on page 24 of this issue, features 100 of the most inspirational professionals involved in A Scientist Walks into a Bar... format to the public”. Generally, drug development. The list was compiled it involves scientists speaking on a based on reader nominations and And gives a presentation as part variety of topics, from medicine, to feedback from a judging panel – but any of Pint of Science, a global science neuroscience, to robotics and more, in list will always be subjective. If there are festival. Taking place in May, the bars and pubs. Find out what’s on near names you would like to see on the 2019 Pint of Science festival aimsto deliver you by visiting the website. list then let us know by nominating now. “interesting and relevant talks on the latest science research in an accessible http://tmm.txp.to/0418/pintofscience http://tmm.txp.to/2019/powerlist Easy as B to D? The Trump Administration’s plans to move Medicare Part B drugs into the Part D system, and to change Part D formulary standards to require a minimum of one drug per category rather than two, would mean additional delays and cost barriers for patients. Angus Worthing, Government Affairs Committee Chair, American College of Rheumatology, gives his thoughts on the matter... http://tmm.txp.to/0418/worthing www.themedicinemaker.com ISSUE 40 - APRIL 2018 Contents Editor - Stephanie Sutton [email protected] Deputy Editor - James Strachan [email protected] Deputy Editor - Roisin Mcguigan [email protected] Content Director - Rich Whitworth [email protected] Publisher - Richard Hodson [email protected] Bringing the future Sales Manager - Helen Conyngham [email protected] Head of Design - Marc Bird [email protected] closer to you. Junior Designer - Hannah Ennis [email protected] Digital Team Lead - David Roberts [email protected] Digital Producer Web/Email - Peter Bartley [email protected] Digital Producer Web/App - Abygail Bradley [email protected] Audience Insight Manager - Tracey Nicholls [email protected] Traffic & Audience Database Coordinator - Hayley Atiz [email protected] Traffic and Audience Associate - Lindsey Vickers [email protected] Traffic and Audience Manager - Jody Fryett [email protected] Traffic Assistant - Dan Marr [email protected] Events Manager - Alice Daniels-Wright [email protected] Marketing Manager - Katy Pearson [email protected] Financial Controller - Phil Dale [email protected] Accounts Assistant - Kerri Benson [email protected] Chief Executive Officer - Andy Davies [email protected] Chief Operating Officer - Tracey Peers [email protected] Senior Vice President, North America - Fedra Pavlou [email protected] 14 Change of address: [email protected] Hayley Atiz, The Medicine Maker, Texere Publishing, Haig House, Haig Road, Knutsford, Cheshire, WA16 8DX, UK General enquiries: www.texerepublishing.com 03 Online This Month Upfront [email protected] +44 (0) 1565 745200 [email protected] 10 In the NIR Future Distribution: 09 Editorial The Medicine Maker (ISSN 2055-8201), is published monthly by Texere Publishing, How Far We’ve Come, by 11 T rials of a Medicine Maker Haig House, Haig Road, Knutsford, Cheshire Stephanie Sutton WA16 8DX, UK Single copy sales £15 (plus postage, cost 12 Gearing up for GDPR available on request [email protected]) Non-qualified annual subscription cost is £110 plus postage 13 Let’s Get Ready to Serialize! Reprints & Permissions – [email protected] The opinions presented within this publication are those of the authors On The Cover and do not reflect the opinions of The Medicine Maker or its publishers, Texere Publishing. Authors are required to disclose any relevant financial APRIL 2018 # 40 14 Blast From the Past arrangements, which are presented at the end of each article, where relevant. © 2018 Texere Publishing Limited. All rights reserved. Editorial Upfront In My View Sitting Down With How far the industry Preparing for Europe’s data What can algae teach us Sophie Kornowski-Bonnet, has come protection regulation about molecular warfare? Roche 09 10 – 11 18 – 19 50 – 51 Balloons, representing the Reproduction in whole or in parts is prohibited. 100 Power List The Power2018 List Power Listers, lift drug 15 Business in Brief 2018 Celebrating the diverse personalities and passions in drug development 24 – 49 development UP! www.themedicinemaker.com 16 Fame and FOYAs Want to know more? Made better. By science. Visit www.capsugel.com Bringing the future closer to you. Want to know more? Made better. By science. Visit www.capsugel.com QUALITY BY DESIGN THROUGH QUALITY MANUFACTURE COMING QUALITY OF SERVICE CLEAN Here’s a little secret… our hygienicyour furnitureclean room and contaminant equipment free. helps keep T: 01603 788 833 | W: teknomek.co.uk | E: [email protected] 24 50 In My View Feature Reports 18 Algae are experts at molecular 24 The Power List 2018 16 The Medicine Maker x CRB warfare and there is much we Our annual Power List celebrates Keeping Fit with Age can learn from them when it the people and personalities comes to designing new driving drug development medicines, says Andrew Dahl. forward, from Masters of the Bench, to Industry Influencers, Sitting Down With 24 Personalized healthcare is a to Business Captains, to really exciting area, according to Champions of Change. 50 Sophie Kornowski-Bonnet, Sophie Kornowski-Bonnet, and Global Head, Roche Partnering. it goes hand in hand with digital technologies. www.themedicinemaker.com Kelsey Kehrli Data Review Scientist PSG | Active ingredients Dynamic people Meet the experts you’ll enjoy working with and discover why we’re one of the biggest names in small molecule APIs. DCAT Week, March 19–22, Lotte NY Palace, New York CPhI North America, April 24–26, Booth 613, Philadelphia www.cambrex.com Custom development Generic APIs Controlled substances & manufacturing How Far We’ve Come Editorial Stop, for just a moment, to contemplate the marvels that pharma has achieved hriving in today’s world is a challenge for both individuals and companies; lower wages butt up against higher living costs, lower profits clash with Thigher operating costs. Add political uncertainty to the mix, and it’s no surprise that depression, anxiety and low self-esteem are reaching record levels. In the midst of this turmoil, what’s our reaction? Taking time out to revel in how far we have come – and celebrating the individuals that make change possible. In March, I had the opportunity to visit Roche headquarters in Basel. As well as touring some of the labs, I also delved into the “Roche Archives” – a vault of company history, including building plans, staff photographs, published articles, and legal documents (even the original document founding the company, signed in 1896). There was also an old machine for making Kelsey Kehrli Data Review Scientist cough medicine, old diagnostic systems, company awards, PSG Roche coat hangers, Roche teddy bears… Countless objects and documents, each with their own part to play in Roche’s success story (photos on page 14). Several big pharma companies apparently maintain such archives – but only rarely are they the subject of a tour. My guide, Active ingredients Alexander Bieri, seemed pleasantly surprised by my wonder at | this room of history. But how can you not be awed by a century- old bottle of medicine (Sirolin)? Roche stores a sample of every Dynamic people medicine ever made by the company, from simple small molecule drugs to the more complex biopharmaceuticals that dominate global pipelines today. The result is an incredible visual reminder Meet the experts you’ll enjoy working of how far the industry has come. with and discover why we’re one of the Yes, it is well accepted that manufacturing processes in pharma tend to lag behind those in other industries. It is also biggest names in small molecule APIs. well accepted that the prices of medicines are spiraling beyond society’s
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