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Management of the 'Young' Patient with Hip Disease

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Management of the 'Young' Patient with Hip Disease ARTHROPLASTY OF THE LOWER EXTREMITIES Management of the ‘Young’ Patient with Hip Disease SCOTT A. RITTERMAN, MD; LEE E. RUBIN, MD ABSTRACT abnormalities lead to impingement within the joint, altered Although hip arthritis typically affects older patients, biomechanics and ultimately cartilage loss.2 Secondary there is a rapidly growing population of “young” patients osteoarthritis can be due to an identifiable cause such as experiencing debilitating symptoms from hip disease. trauma to the femoral head, post-infection arthritis, slipped Most commonly, osteoarthritis and avascular necrosis af- capital femoral epiphysis, or hip dysplasia. fect this population, but a variety of other primary struc- As we age, the water content of cartilage increases with tural and metabolic causes can also occur. The expecta- a concomitant decrease in protein content, both leading to tions of these younger patients are often distinct from degeneration. The progressive loss of the cartilage matrix geriatric patients, and the challenges in optimizing their leads to recurrent bouts of inflammation as bone contacts care are unique in this demanding population. Selection bone, and reactive bone called osteophyte forms around the of the implant, bearing surface, and surgical technique joint. In the subchondral bone, hardening and cyst formation can all impact the success and longevity of total hip re- occurs. Repeated bouts of inflammation also extend into the placement. A consideration for respecting the native peri-articular soft tissues leading to deformity and contrac- bone stock is an important consideration that can poten- tures of the capsule, supporting ligaments, and tendons. Put tially reduce some of the future challenges of revision ar- together, these changes lead to pain, stiffness, and gait dis- throplasty in this young population. turbances. Its commonality among close relatives hints at a 1 KEYWORDS: total hip replacement (THA), neck sparing genetic predisposition, which is not currently understood. arthroplasty (NSA) Avascular Necrosis Avascular necrosis, also known as osteonecrosis, is the most common reason for advanced hip arthritis in the young pa- Diagnosis and Management of Hip Disease tient.3,4 Avascular necrosis occurs when the bone in the fem- in the Young Patient oral head loses its blood supply. The weakened bone leads Advanced arthritis of the hip joint can lead to profound to cyst formation and collapse of the bony architecture with changes in quality of life. Debilitating pain, stiffness, and a resulting deformation in the shape of the femoral head. altered gait biomechanics all affect the ability to stay mo- This painful process results in a rapidly progressing arthritis. bile and maintain gainful employment; these concerns are Common causes are alcohol abuse, prolonged use of corti- magnified in the younger patient with hip disease. While hip costeroids, hypercoagulable states (ie. Sickle cell disease5 or arthritis typically affects older patients, there is a significant lupus) and trauma to the hip resulting in altered blood flow subset of active patients in their 30s, 40s, and 50s who are to the femoral head. Smoking is also postulated to have a affected and were previously thought of as, “too young for a role in the microvascular manifesations of the disease. hip replacement.” Over the last several decades, advances Many other cases are idiopathic in nature. Initial treat- in hip replacement surgery are allowing us to rethink that ment begins with medical management and may include position. Two major causes of advanced arthritis in young anti-inflammatory medication. Some studies have demon- patients are primary (idiopathic) osteoarthritis and avascular strated bisphosphonate use may delay or prevent femoral necrosis. Most of the remaining cases are caused by inflam- head collapse; further studies have not supported it. Though matory arthropathies, infections, trauma and congenital or many have been investigated, there is no single pharmaco- developmental anatomical abnormalities.1 logical agent that can prevent the naturally advancing course of osteonecrosis.4 Osteoarthritis If significant pain relief is not achieved with conservative Osteoarthritis is a chronic degenerative condition that is care, most patients turn to surgical management. When associated with, but not caused by, aging. It can be catego- diagnosed early before collapse of the femoral head, a core rized into primary or secondary causes. Primary osteoarthri- decompression can be performed to preserve the joint. In tis remains idiopathic in nature. While its exact pathophys- this procedure, a canal is drilled into the femoral head with iology is unknown, some believe that minor developmental the hope of reducing the intraosseous pressure to relieve MARCH 2013 RHODE ISLAND MEDICAL JOURNAL 26 ARTHROPLASTY OF THE LOWER EXTREMITIES pain, and stimulate a healing response in the femoral head low functional demands, it will not suffice for patient with by increasing blood flow. Typically these techniques relieve advanced arthritis in their 30s. For this reason, in the past pain, but often only delay eventual femoral head collapse. many surgeons were reluctant to perform joint replacement Unfortunately, many of these patients will still develop fem- surgeries in young patients for fear of condemning them to oral head collapse and the associated findings of acute-onset multiple revisions over a lifetime of use. With current tech- severe arthrosis associated with debilitating pain, and will nology, we can now provide young and active patients with then need a hip replacement. long lasting pain relief with the confidence that we will be able to revise these prostheses in the future if needed. Presentation and Management The ideal hip replacement prosthesis for a young patient Common symptoms of hip arthritis include pain in the groin, would be easily integrated, forming a long lasting bond with especially while weight bearing and increasing with use. The the host bone, yet be easily removed if needed. Most mod- arthritic hip is typically stiff in the morning and the patient ern hip prostheses are made of titanium and are cementless. may note difficulty getting up from a chair after a prolonged They use biological ingrowth for osseous integration of both time seated. There is a noted decreased range of motion and the femoral and acetabular components. The prosthesis is activity tolerance, with particular difficulty in donning socks typically coated with thousands of tiny particles that give and tying shoelaces. The resulting disuse of the hip second the surface a roughened appearance. Between these tiny me- to pain leads to atrophy of the musculature. Muscle weak- tallic pores are spaces where the host bone actually grows ness, in addition to avoiding weight bearing on the affected onto the prosthesis. extremity, can lead to the development of an antalgic limp. A Bearing surfaces are the parts of the prostheses that glide cane or crutch may be used to offload body weight, and pain across one another to allow motion at the joint. In the past, may also be referred to the lower back or ipsilateral knee. many different products were used including ivory, glass, Nonsurgical management of arthritis is typically geared plastic and metal. Today popular choices include either toward the inciting factor whether that is stopping an of- a metal (cobalt-chrome) on plastic (called polyethylene), fending agent (steroids, alcohol), or the use of disease modi- ceramic on plastic, ceramic on ceramic. Metal on metal fying anti-rheumatic drugs (DMARDs) in inflammatory ar- remains an option, but has fallen out of favor due to poor thropathies. Virtually all patients with arthritis can benefit clinical performance and implant recalls. from other nonsurgical interventions such as weight loss, As the bearing surfaces rub against each other, the ma- activity modification and anti-inflammatory medications. terials begin to wear, shedding tiny micron-sized particles, Each patient is affected differently and it is difficult to know each at a different rate. Previously, plastic wear particles the expected rate of progression in each. generated when the head of the prosthesis rubbed on the Patients in significant pain and discomfort will typically plastic liner were responsible for a phenomenon termed seek the help of a hip specialist. For those who quickly ‘osteolysis.’ Osteolysis is an inflammatory condition led progress to debilitating arthritis, a replacement may be the by an activated macrophage response to ingested plastic only option regardless of age. In the past, younger patients particles which leads to periprosthetic bone loss result- had limited surgical options. Hip arthrodesis, or fusion, had ing in implant loosening or fracture.8 This has largely (but poor results with limited functionality and frequently lead not completely) been solved with the highly engineered to atrophy of hip musculature and pericapsular contractures “cross-linking” of the polyethylene molecules that makes it making reversal difficult. Deficient hip abductors predispose almost a thousand times more resistant to wear. to dislocation as well. 3 Healthy, young, active patients with Ceramic bearings are quickly becoming the preferred advanced arthritis are ideal candidates for a replacement due bearing surface in the young and active patient.6,9,10 These to their good muscle tone and ability to remodel bone and en- bearings have lower wear rates than metal on plastic com- joy predictable increases
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