Registration Lead Centre Co‐lead Centre Lead Last Name Lead First Name Lead Institution Co‐Lead(s) Project Title Research Keywords No. 11601 Genome Ontario Beiko Rob Dalhousie University Andrew McArthur Rapid prediction of antimicrobial resistance from metagenomics samples: data, metagenomic profiling, phenotype prediction, antimicrobial Atlantic Genomics Fiona Brinkman models, and methods resistance 11602 Genome Beiko Rob Dalhousie University Graham Gagnon Comprehensive real‐time analysis of sequences in a hurry (CRASH): Algorithms, Comparative microbial genomics, multi‐omic analysis, real‐time Atlantic Fiona Brinkman software and databases to support real‐time metagenomic analysis of sequence 11603 Genome Bertrand Erin Dalhousie University Rob Beiko From next generation sequencing to quantitative proteomic assay development microbial community and microbiome function, protein Atlantic Douglas Campbell in microbial systems dynamics, multiomic analyses, interdisciplinary knowledge 11604 Genome Bielawski Joe Dalhousie University Hong Gu Novel analytical methods for personalized predictive care of complex diseases Metagenomics, Human genetics, Inflammatory bowel disease, Atlantic Toby Kenney associated with dysbiosis of the human microbiome Predictive modeling, Personalized clinical care 11605 Genome Hu Ting Memorial University Guangju Zhai Evolutionary computing approach to detecting and characterizing heterogeneity Gene‐gene interaction; Epistasis; Heterogeneity; Genetic Atlantic and epitasis in genome‐wide association studies association 11606 Genome Langille Morgan Dalhousie University Daniel Gaston Creation of a human microbiome interaction knowledge base microbiome, metagenomics, human genetics, interactions, Atlantic disease 11607 Genome Myles Sean Dalhousie University A tool to maximize the impact of genotype imputation Next‐generation DNA sequencing; Genome‐wide association Atlantic studies; 11608 Genome Pena‐Castillo Lourdes Memorial University Michael Woods Characterizing and analyzing genetic variation of the Newfoundland population Human genetic variation, population genomics, population Atlantic genetics, 11201 Genome Dinu Irina University of Alberta A bioinformatics platform for handling and analysis of large data generated by Microbiome, OMICS, multivariate continuous phenotypes, high Alberta biotechnologies, including complex study designs dimensionality 11202 Genome Han Jie University of Alberta Hasan Uludag Tools and Methodologies for the Analysis and Validation of Cancer Networks and Cancer genomics, gene network, Signaling pathway, Drug target Alberta Pathways toward Personalized Medicine identification, Personalized medicine 11203 Genome Hazes Bart University of Alberta Paulo Nuin Next generation sequencing pipeline for clinical diagnostics and surveillance Mitochondrial disease diagnostics, Haplotype determination, Alberta Viral pathogen diagnostics, genotyping, Single Nucleotide 11204 Genome Long Quan University of Calgary Method development for large structural variants discovery using related species Plant genome sequencing; Structural variants discovery; False Alberta positive control; Mutational trajectory; 11205 Genome Long Quan University of Calgary Method development for genomic variant discovery leveraging within‐host Genomic variant discovery; False positive control; Private Alberta population genetics mutation; Precision medicine 11206 Genome Schriemer David University of Calgary Marc Strous Development of informatics solutions for microbiome research using the Mass Pan‐omics, microbiome. Alberta Spec Studio 11207 Genome Tieleman Peter University of Calgary Justin MacCallum MD Access Biochemistry, biophysics, biotechnology, platform technology Alberta 11208 Genome Winsor Robin Cybera Jason DeKoning Container based, interoperable genomics workflow for analytics Genomics workflows, reproducible analytics Alberta Jordan Engbers 11209 Genome Wishart David University of Alberta Novel Informatics Tools for Multi‐omics Biomarker Discovery and Validation Biomarker identification, biomarker databases, disease Alberta identification 11210 Genome Wishart David University of Alberta Automated Compound Identification and Quantification for Multiple Metabolomics, compound identification, compound Alberta Metabolomics Platforms quantification, automation 11211 Genome Yang Rong‐Cai University of Alberta Development of Virtual Cross Platform (VCP) for multiple trait genomic selection Statistical genomics, computational biology, cereal breeding, Alberta in plant breeding genomic selection, quantitative genetics, bioinformatics 11101 Genome BC Birol Inanc BC Cancer Agency New bioinformatics for new sequencing technologies: Genome characterization genome assembly; transcriptome assembly; sequence alignment; and variation detection using long reads variant 11102 Genome BC Birol Inanc BC Cancer Agency Caren Helbing Mining the bullfrog genome for novel cancer drugs and antibiotics anticancer drug discovery; cancer therapy; antimicrobial compound 11103 Genome BC Borchers Christoph University of Victoria MADpipe – Multiple and parallel reaction monitoring Assay Design and analysis Automation, information integration, workflow, targeted pipeline proteomics, absolute quantification 11104 Genome BC Breden Felix Simon Fraser University Jamie Scott iReceptor: Integration of Adaptive Immune Receptor Repertoire Data for Immune repertoires; vaccines, therapeutics, cancer Biomedical Research and Patient Care immunotherapy; 11105 Genome BC Brinkman Ryan BC Cancer Agency Cedric Chauve Automated analysis of big flow cytometry data International Mouse Phenotyping Consortium, Inflammatory Sara Mostafavi Bowel Disease, gene function, immunology, personalized 11106 Genome BC Chindelevitch Leonid Simon Fraser University William Hsiao Calibrated multi‐variant genomic analysis for public health microbiology infectious disease, epidemiology, genomic evolution, WGS, data Cedric Chauve integration 11107 Genome BC Friedman Jan University of British Inanc Birol Improving the sensitivity of whole genome sequencing as a clinical test for Clinical testing, structural variants, trinucleotide repeats, copy Columbia genetic causes of intellectual disability number 11108 Genome BC Hallam Steve University of British Global scale metabolic pathway reconstruction from environmental genomes Metagenomics, environmental genomics, microbial systems Columbia ecology, biological engineering, bioeconomy 11109 Genome BC Hancock Bob University of British Fiona Brinkman Integrative Network‐based Analysis of Host‐Pathogen Interactions Molecular interactions, data integration, host‐pathogen Columbia interactions, 11110 Genome BC Hirst Martin University of British Steven Jones Epigenomic Tool Development Epigenomics, DNA methylation, Histone Modification, Software Columbia Development 11111 Genome BC Ontario Hsaio William University of British Andrew McArthur Genomic Epidemiology Application Ontology (GenEpiO) Genomic Epidemiology, Antimicrobial Resistance, Ontology Genomics Columbia Development 11112 Genome BC Huntsman David University of British Robust clustering of genomic data for cancer subtype discovery Class discovery, cancer subtype, clustering, unsupervised Columbia learning, cluster 11113 Genome BC Lorincz Matt University of British Mohammad Mahdi An interactive cloud‐enabled visual platform for systematic analysis of large‐scale epigenomics, transcriptomics, next generation sequencing, Columbia Karimi sequencing datasets differential 11114 Genome BC Paci Irina University of Victoria Connectivity tools for bridging bioinformatics, biomolecular simulations and Data analysis, protein‐ligand interaction, genetic expression, risk Omics‐informed drug design and diagnosis alleles, 11115 Genome BC Pavlidis Paul University of British An interactive web‐based system for exploration of complex phenome‐genome whole genome sequencing, whole exome sequencing, Human Columbia datasets genetics, deep phenotyping, genome‐phenome analysis 11116 Genome BC Poon Art University of British Kamphir ‐ an open‐source software package for phylodynamics with approximate phylodynamics, virus evolution, molecular epidemiology, Columbia Bayesian computation speciation, network modeling 11117 Genome BC Poon Art University of British Kive: A new framework for the automation and version control of bioinformatic translational bioinformatics, clinical genomics, next‐generation Columbia pipelines and data sequencing 11118 Genome BC Ritland Kermit University of British Sequencing error and identification of true haplotype Bioinformatics, haplotype inference Columbia 11119 Genome BC Sahinalp Cenk Simon Fraser University Colin Collins Novel Algorithms for Detecting the Clonal Composition and Monitoring the Clonality detection, monitoring tumor evolution, copy number Clonal Evolution of Tumors via Liquid Biopsies variation detection, liquid biopsy analysis, potential application to 11120 Genome BC Shah Sohrab University of British Genome analytics for cancer population dynamics at single cell resolution Single cell sequencing, statistical modeling, Bayesian statistics, Columbia tumour evolution, cancer population dynamics 11121 Genome BC Tebbutt Scott University of British RNA‐seq tools for cell type‐specific deconvolution in peripheral whole blood Whole blood transcriptome; Leukocyte counts and differentials; Columbia Deconvolution; Cell‐specific gene expression; Immune cell profiles 11122 Genome BC Upton Chris University of Victoria A database to support comparative genomics analyses of human and animal viral Bioinformatics, virology, poxvirus, African swine fever virus, pathogens. monkeypox 11123 Genome BC Wasserman Wyeth University of British Discovery, Characterization, and Design of cis‐Regulatory Elements Controlling Gene Regulation, Human Genetics, Gene Therapy, Development, Columbia Human Gene Expression Vision 11301 Genome Ontario Babu Mohan University of Regina James Vasblom An Integrated Application Suite for the Analysis and Reporting of Pathways and Bioinformatics, Computational biology, Neurological disorders, Prairie Genomics Variants for Neurological Disorders Quantitative Genetics, Network/Integrative biology 11302 Genome Beavis Ronald University of Manitoba Proteome‐to‐Genome PTM Annotation Pipeline and User Interface Genome analysis, proteomics, post‐translational modifications, Prairie personalized medicine, single nucleotide variants 11303 Genome Kusalik Anthony University of Christopher Eskiw Development of Computational Techniques for the Comprehensive Analysis of Hi‐ Software Development, Three‐Dimensional Genome Organization Prairie Saskatchewan C Datasets 11304 Genome McQuillan Ian University of Brian Eames Machine‐learning processes to identify GRNs underlying skeletal health Machine learning, Gene regulatory networks, musculoskeletal Prairie Saskatchewan health 11305 Genome Pemberton Trevor University of Manitoba Inference and interpretation of genomic autozygosity patterns in next generation Autozygosity; consanguinity; genomics; identity by descent; Prairie genomics data inbreeding 11306 Genome Plummer Francis University of Manitoba Jason Cassidy Understanding HIV resistance: develop deep learning algorithm for predicting HIV resistance, Genome wide SNPs analysis, genomics and gene Prairie Ma Lou susceptibility to HIV infection and disease expression 11307 Genome Sharpe Andrew University of Isobel Parkin Implementation of bioinformatics for improved analysis of complex genomes and Next generation sequencing, genetic mapping analysis, structural Prairie Saskatchewan acceleration of crop breeding variation (PAV and SV), epigenomic sequence data 11308 Genome Wu Fang‐Xiang University of Developments of Bionetwork‐Based Methodologies for Drug Repositioning drug repositioning, drug discovery, complex diseases, Prairie Saskatchewan biomolecular networks, genomic data 11309 Genome Xu Wayne University of Manitoba Jim Davie Diverse genomic data integration pipeline program and a large data sharing Genomic data format, Next‐generation sequencing, GeneChip, Prairie platform data sharing platform 11501 Genome Badard Thierry Université Laval Jacques Corbeil Location analytics and machine learning algorithms to predict antibiotic Drugs resistance, spatiotemporal metadata, global health Quebec resistance monitoring, 11502 Genome Blanchette Mathieu Université McGill Josée Dostie Bioinformatics platform for the analysis of chromosome conformation in cancer Bioinformatics, Chromatin structure, 3D genomics, Cancer, Quebec Genome rearrangements, Gene regulation. 11503 Genome Bourque Guillaume Université McGill GenomeProfiler: a public web app for interactive visualization and supervised Genomics, epigenomics, ChIP‐seq Quebec machine learning 11504 Genome Bureau Alexandre Université Laval Arnaud Droit ClusterCoseg: a bioinformatics tool to detect genomic regions involved in 3D genome structure, genomic sequencing, pedigrees, rare Quebec complex diseases in family studies variants, 11505 Genome Butler Greg Université Concordia ― D2K: a next generation platform for omics big data to knowledge, a pilot study annotation, machine learning, provenance network, graph Quebec mining, information visualization 11506 Genome Chakravarty Mallar Douglas A full connectomics platform for psychosis and mental health Schizophrenia, mental health, magnetic resonance imaging Quebec 11507 Genome Genome Prairie Charest Hugues Université de Montréal Susan Detmer An integrated monitoring system for human, avian and swine influenza Respiratory pathogens, influenza viruses, zoonotic infections, Quebec surveillance active surveillance of emerging pathogens 11508 Genome Charette Steve Université Laval Sylvain Moineau PhaGoSafe: A webserver to assess the therapeutic potential of phages against Drug resistance, phage therapy, big data management, genotype Quebec bacterial infections through genomic information to phenotype, ontology optimization 11509 Genome Corbeil Jacques Université Laval François Laviolette Predictive Computational Phenotyping of multiomic Cancer Data Cancer, breast, head and neck, glioblastoma, clinical Quebec management 11510 Genome Dendukuri Nandini CR‐CUSM Jyothi Prabhu Development of an integrated approach through latent class modelling for breast cancer, sub‐types, prognosis Quebec T. S. Sridhar identification of breast cancer subtypes of clinical relevance 11511 Genome Dewar Ken Université McGill Roger Lévesque Tomorrow's Genome: next‐day reporting for clinical and food pathogen bacterial pathogens, infectious diseases; food and water borne Quebec outbreaks pathogens; genetic diversity; epidemiology 11512 Genome Droit Arnaud CHU de Québec Steve Bilodeau Predicting the molecular causes of transcription‐based diseases Epigenomics, Transcriptional regulation, Genetic variations, Non‐ Quebec coding 11513 Genome Dubé Marie‐Pierre ICM ― Post‐Hit: A public data portal for functional annotation of genomic regions Annotation, contextualization, variant interpretation, data Quebec integration, gene 11514 Genome Dubé Marie‐Pierre ICM ― A phenotype manager to improve genetic association studies Phenomics, cohort, ontology, data management, genetic Quebec association 11515 Genome Gravel Simon Université McGill Jacek Majewski A Modelling Toolbox for Clonal and Spatial Evolution of Tumors Cancer, clonal evolution, sub‐population, metastasis, spread Quebec 11516 Genome Greenwood Celia Institut Lady Davis Aurélie Labbé System‐wide environmental perturbations transform understanding of Gene‐environment interaction, prediction models Quebec relationships between high‐dimensional data, exposures, and phenotypes 11517 Genome Grundberg Elin Université McGill Tomi Pastinen The iGENE portal‐ An integrative GENomics and Epigenomics tool for next‐ Disease genomics and epigenomics, population variation, Quebec generation complex disease bioinformatics integrative 11518 Genome Hallett Michael Université McGill Sein‐sense: software that enables women to explore their breast cancer Breast cancer, bioinformatics, precision medicine, systems Quebec biology, patient empowerment 11519 Genome Jacques Pierre‐Étienne Université de Development of an efficient bioinformatics tool to help the characterization of Bioinformatics tool development, epigenomic data set Quebec Sherbrooke epigenomic private data sets using thousands of publicly available data sets characterization, 11520 Genome Jenna Sarah UQAM Abdoulaye Banire MyMs (My‐oMics), my artificial personal research assistant specialized in Intelligent omics, bioinformatics workflows, artificial research Quebec Diallo genomics assistant 11521 Genome Kleinman Claudia Université McGill Integrating genome‐wide data to model dynamic biological processes Transcriptomics, Epigenomics, Differentiation, Development Quebec 11522 Genome Lakhal‐Chaieb Lajmi Université Laval Karim Oualkacha Rare variants association tests with censored traits Rare variants, censored traits, cure fraction Quebec 11523 Genome Lamoureux Guillaume Université Concordia Yoshua Bengio Predicting protein‐protein interactions with deep learning protein‐protein interactions, proteomics, interaction networks, Quebec protein 11524 Genome Landry Christian Université Laval Nicolas Bisson Predicting the function of driver fusion proteins in cancer for better therapy Cancer; Protein fusion; Evolution; Protein structure; Driver Quebec development and prognosis mutation; Passenger mutation; Genomics; Therapy; Precision 11525 Genome Lang Franz Université de Montréal Gertraud Burger A novel iterative method to assembly genomes from multiple‐genome or Iterative genome assembly; error correction; multi‐genome or Quebec metagenomic data metagenomic NGS data; genome finishing with mate‐pairs and/or 11526 Genome Lathrop Mark Université McGill Audrey V. Grant Optimization of complexity reduction of pathogen whole genome sequencing Infectious diseases, virulence, Plasmodium genetics, human Quebec data and human genotype or sequencing data for the investigation of human‐ genetics, 11527 Genome Laviolette François Université Laval Marc Pouliot A Machine Learning Tool for Rheumatoid Arthritis Diagnosis Arthritis, learning algorithm development, diagnostic, biomarkers Quebec 11528 Genome Lemieux Sebastien Université de Montréal ― Development of an integrated set of tools for k‐mer profiling of large RNA‐Seq Cancer, leukemia. Quebec cohorts 11529 Genome Major François Université de Montréal Computation of cell‐specific microRNA::mRNA regulatory networks enables the MicroRNA‐mediated gene regulation, gene regulatory networks, Quebec design of efficient RNAi‐based therapeutics genome‐wide identification of microRNA targets, stoichiometric 11530 Genome Major François Université de Montréal Computation and analysis of genome‐wide RNA dynamics maps RNA structure and dynamics, structure‐activity relationships, Quebec pattern discovery, differential genome‐wide analysis, RNA‐ 11531 Genome Nadon Robert Université McGill Vladimir Estimation and Correction of Bias in High‐Throughput Functional Genomics Data High‐throughput screens; RNAi; off‐target effects; systematic Quebec Makarenkov error in screening technologies 11532 Genome Najafabadi Hamed Université McGill An integrated framework for normalization of ChIP‐seq data without control Protein‐DNA interaction, transcription factors, chromatin, Quebec libraries using public genomics databases epigenome, sequence analysis 11533 Genome Ontario Najmanovich Rafael Université de Gabriel Wainer Integration of omics datasets in multi‐scale modelling of whole cells using Multiscale cellular modeling Quebec Genomics Sherbrooke Discrete Event Systems Specification 11534 Genome Najmanovich Rafael Université de DrugIT: A citizen‐science game for drug discovery Drug design Quebec Sherbrooke 11535 Genome Najmanovich Rafael Université de AdFx: A ResearchKit‐based mobile app to monitor adverse effects of drugs and Drug toxicity, Personalized medicine Quebec Sherbrooke drug combinations 11536 Genome Oualkacha Karim UQAM Lajmi Lakhal‐Chaieb Biostatistical methods for MethylC‐Seq data DNA methylation, experimental errors, MethylC‐Seq data, spatial Quebec correlation, low coverage. 11537 Genome Pechmann Sebastian Université de Montréal Integrative framework for the characterization of auxiliary factors in biological Integrative genomics, network biology, systems biology, Quebec systems biological 11538 Genome Genome BC Porth Ilga Université Laval Yousry A El‐Kassaby A community resource for tree breeders and researchers based on an integrative Population genomics, quantitative genomics, selective breeding, Quebec database, analysis and reporting system of functional genomic data in a web‐ transcriptomics, web‐based application 11539 Genome Rivière Jean Baptiste CR‐CUSM Software development for detecting genetic mosaicism in human disease Genomics; Bioinformatics; Human Disease; Mosaicism Quebec 11540 Genome Salavati Reza Université McGill A general platform for analysis of parasite genome sequences towards drug Computational analysis, pathogenic parasite genomes, essential Quebec target discovery genes, targets for chemotherapeutics 11541 Genome Sato Masahiko CHU de Québec Sachiko Sato Cell lineage database: A next generation of bioinformatics resource for cell Single cell lineage tracking analysis, Automated live cell imaging, Quebec biological and genomic research Cell lineage database, In silico characterization of cultured cells, 11542 Genome Serohijos Adrian Université de Montréal Developing Novel Tools for Detecting Adaptive Evolution in Genomes by Molecular evolution, Biophysics, Neutrality Test, Detecting Quebec Integrating Protein Biophysics with Population Genetics Selection, Protein evolution 11543 Genome Serohijos Adrian Université de Montréal Developing a multiscale and predictive framework for microbial evolution Bacterial Evolution, viral evolution, antibiotic resistance, Quebec neutralizing antibody, protein biophysics 11544 Genome Shapiro Jesse Université de Montréal Luis Barreiro A toolkit for genome‐wide association studies in bacteria host‐pathogen interactions, co‐evolution, natural selection, Quebec microbiology, 11545 Genome Soudeyns Hugo CHUSJ Abdoulaye Banire VIRGO: an integrated computational environment for viral bioinformatics Virology; human immunodeficiency virus (HIV); hepatitis C virus; Quebec Diallo influenza 11546 Genome Stromvik Martina Université McGill Towards a sustainable and food secure future: Developing an integrated Plant ‘omics analyses and digital agriculture for a sustainable and Quebec computational toolset for plant ‘omics analyses and digital agriculture food 11547 Genome Thomson Axel CR‐CUSM Sébastien Lemieux Development of cancer sample deconvolution methods to define stromal content Cancer, prognostic test, tumour signatures, deconvolution, Quebec in tumor types with known microenvironment involvement to improve tumour stroma 11548 Genome Waldispühl Jérôme Université McGill Computational methods and databases to identify small RNA‐binding molecules ncRNA, small molecule, binding, structure, gene regulation, drug Quebec regulating gene expression target. 11549 Genome Waldispühl Jérôme Université McGill Crowdsourcing genomic databases Databases, RNA, annotation Quebec 11550 Genome Wang Edwin Université McGill André Nantel Detecting of early breast and ovarian cancers by developing a network‐based Cancer diagnosis, genome sequencing Quebec algorithm 11551 Genome Wilhelm Brian Université de Montréal Sébastien Lemieux Development of a cancer genomics VM Cancer genomics, human‐computer interface, data‐mining Quebec techniques, 11552 Genome Xia Jianguo Université McGill Next generation bioinformatics platform to integrate gut microbiota, metabolism Gut microbiota, metabolism, immune systems, diet, host‐ Quebec and host immunity environment interactions 11553 Genome Yergeau Etienne INRS‐Institut Armand‐ Julien Tremblay Harnessing the predictive power of metagenomes for agriculture, forestry and Soil microbiome, soil microbial ecology, nutrient cycling, soil Quebec Frappier the environment health, ecosystem services 11401 Ontario Arts Eric Western Greg Gloor New genetic tools and bioinformatics to resolve copy number variation and Plasma lipoprotein a, cardiovascular disease, large segment Genomics unresolved genomic regions: Apo(a) gene as test case genome cloning/sequencing 11402 Ontario Awadalla Philip OICR Novel Methods for Data Integration for Deeply Characterized Population Cohorts Prospective population cohorts, longitudinal data, Genomics endophenotypes, outcome, mutation load, dominance 11403 Ontario Bickel David U of Ottawa Leveraging advances in Bayesian statistical methods to interpret genomics data biostatistics, statistical bioinformatics, empirical Bayes data Genomics analysis, 11404 Ontario Boutros‐1 Paul OICR Enhanced and Automated Visualization of Complex Genomic Data Bioinformatics, computational biology, cancer biology, genomics Genomics 11405 Ontario Boutros‐2 Paul OICR Automatic Optimization of Computational Pipelines Bioinformatics, computational biology, cancer biology, genomics Genomics 11406 Ontario Boutros‐3 Paul OICR Improving the Statistical Robustness of Data‐Mining Bioinformatics, computational biology, cancer biology, genomics Genomics 11407 Ontario Boutros‐4 Paul OICR Enhancing the quality‐control of DNA Sequencing data Bioinformatics, computational biology, cancer biology, genomics Genomics 11408 Ontario Boutros‐5 Paul OICR Techniques for Generalizable Biomarker Discovery Bioinformatics, computational biology, cancer biology, genomics Genomics 11409 Ontario Bratman Scott UHN Benjamin Haibe‐ RadioGenomics and PharmacoGenomics: Integrated prediction tools for Oncology, radiotherapy, genomics, radiogenomics, biomarker Genomics Kains combining radiotherapy with systemic agents 11410 Ontario Brudno Michael Sick Kids James Dowling RNAseq in patient‐derived ex‐vivo models: next generation diagnostics beyond Diagnostics; ex‐vivo disease models; genetic testing; Genomics whole exomes 11411 Ontario Brudno Michael Sick Kids Rebecca Weksberg EpigenCentral: consolidated epigenetic landscape for neuro‐developmental Bioinformatics, epigenetics, neurodevelopmental disorders, Genomics disorders genetic mutations 11412 Ontario Brudno Michael Sick Kids PatientKind: a Social Network for Rare Disease Patients Rare disease; social networks; medical informatics Genomics 11413 Ontario Chang Belinda U of Toronto Development of a phylomedicine toolkit for identifying disease‐associated Phylomedicine, disease variant prediction, SNVs, in silico Genomics mutations using genome data diagnosis, retinal dystrophies 11414 Ontario Dehne Frank Carleton U InSiPS: The in silico protein synthesizer Protein‐protein interaction; synthetic biology; protein design Genomics 11415 Ontario Doxey Andrew Waterloo Josh Neufeld MetIndicate: a machine‐learning framework for metagenomic biomarker Comparative metagenomics, bioinformatics, machine‐learning, Genomics discovery and diagnostics human gut microbiome, diagnostics 11416 Ontario Evans Kenneth Indoc Research Igor Jurisica Indoc QC+BioInfo – Powering Incorporation of QC Metrics and Biological QA/QC metrics, biological pathway Genomics Information in Downstream Analysis 11417 Ontario Feng Zeny U of Guelph Sanjeena Dang Novel computational and statistical tools for microbiome data analysis Microbiome, sequencing data analysis, computational statistics, Genomics statistical 11418 Ontario Ferretti Vincent OICR Ivan Borozan vINFER: An integrative framework for the characterization of the human virome Metagenomics, virome, sequence analysis, bioinformatics Genomics platform 11419 Ontario Ferretti Vincent OICR Brian O'Connor Dockstore: A platform for sharing cloud‐agnostic tools with the research Genomics, bioinformatics, computational biology, data science Genomics community 11420 Ontario Gingras Anne‐Claude LTRI, Mt Sinai A navigatable physical map of a human cell Subcellular Organization, Protein Interactions, Protein Networks, Genomics Collaborative Projects, Dissemination 11421 Ontario Genome BC Goldenberg Anna Sick Kids Sara Mostafavi Inferring disease trajectories and their causes Machine Learning, Time Series Analysis Genomics 11422 Ontario Goldenberg Anna Sick Kids A new pipeline for functional gene annotation via omics data integration Machine learning, gene regulation Genomics 11423 Ontario Golding Brian McMaster Ben Evans Tracking the Response to Climate Change with Genomics Monitoring climate change effects on native and invasive species Genomics Ian Dworkin using genomic data: developing and standardizing a database and 11424 Ontario Golding McMaster McMaster Hendrik Poinar Determining changes in emerging pathogen genomes Emerging Bacterial Diseases: finding the characteristics that Genomics Gerry Wright enable these bacteria and learning the nature of these changes. 11425 Ontario Graber Tyson CHEO Marcel Turcotte Deploying a standardized, modular, and accessible analysis workflow for Genome, transcriptome, translatome, ribosome, functional Genomics Tommy Alain ribosome profiling and downstream functional analysis. analysis 11426 Ontario Gupta Radhey McMaster Development of a Web‐Based Microbial Identification Tool Based Upon Conserved Signature Indels, Conserved Signature Proteins, Genomics Conserved Signature Indels and Proteins which are Specific for Different Microbial Identification, Metagenomics, Comparative Genomics, 11427 Ontario Genome Quebec Haibe‐Kains Benjamin UHN Morag Park Pancancer Tumor Microenvironment, Anticancer Therapy, Genomics inference of crosstalk between epithelial and stromal cells Pharmacogenomics 11428 Ontario Haibe‐Kains‐1 Benjamin UHN Anna Goldenberg Integrative pharmacogenomic framework for prediction of synergistic anticancer Pharmacogenomics, Anticancer Therapy, Biomarkers Genomics drug combinations in vitro 11429 Ontario Haibe‐Kains‐2 Benjamin UHN Anna Goldenberg Computaonal plaorm for robust drug response predicon across cancer model Pharmacogenomics, Anticancer Therapy, Biomarkers Genomics systems 11430 Ontario Hoffman Michael UHN Semi‐automated genome annotation: the next generation epigenomics, chromatin, ChIP‐seq, ATAC‐seq Genomics 11431 Ontario Ingalls Brian Waterloo John Parkinson Systems modelling of metabolic behaviour in microbiomes: exploiting Microbomes (1), metabolomics (1), metabolic networks (1), Genomics David McMillen metabolomics datasets metagenomics 11432 Ontario Ioshikhes Ilya U of Ottawa Interaction of eukaryotic gene regulatory elements Bioinformatics, gene regulation, chromatin, transcription, miRNA Genomics 11433 Ontario Jaffray David Techna Inst. UHN Trevor Pugh Interpreting integrated clinical genomics data to support cancer care Cancer, data integration, machine learning, genome Genomics interpretation 11434 Ontario Jurisica Igor PMCC, UHN Comprehensive Signalling Biology Platform for Precision Medicine Dynamic modeling, physical protein‐protein interactions, Genomics signaling cascades, cancer, arthritis, curation. 11435 Ontario Kari Lila U of Waterloo Paul Hebert Extracting Signal from Noise: Big Biodiversity Analysis Metabarcoding, biodiversity, genomic signatures, data mining, Genomics bioinformatics 11436 Ontario Kelvin David UHN Computational methods for bacterial transcriptomic analysis in complex systems Microbiome, gene expression, computational biology Genomics 11437 Ontario Kim Philip U of Toronto A structural platform enabling drug discovery for personalized medicine Structural biology, disease mutations, drug discovery Genomics 11438 Ontario Genome Quebec Lerner‐Ellis Jordan Mt. Sinai Bartha Knoppers Collaborative Network for Clinical Genomics: CONCErt Medical Genomics, Phenotype‐Genotype, Personalized Medicine, Genomics Patient Aid, Patient Consenting and Governance Policies 11439 Ontario Liang Ping Brock Development of tools and databases for more accurate and faster variant analysis Personal genome, genome variants, structural variation, database Genomics in personal genomes 11440 Ontario Mazalek Alexandra Ryerson Paul Boutros Grasping mtDNA: tangible visualization tools for enhancing genome data analyses Genomics, computational biology, molecular biology, Genomics Matthew Kyan of mitochondrial DNA, 11441 Ontario McConkey Brendan U of Waterloo Determining specificy of responses in high‐throughput datasets Differential gene expression, meta analysis, statistical contrasts, Genomics pathway specificity 11442 Ontario Meyre David McMaster Testing the potential of candidate gene wide association study (CANWAS) to Cardio‐metabolic traits; Genome‐wide association studies; High‐ Genomics identify novel genes predisposing to cardio‐metabolic diseases throughput candidate gene studies; Integrative Biology; Missing 11443 Ontario Morris Quaid U of Toronto Robust software and methods for reconstructing the evolutionary history of Cancer, evolution Genomics tumours 11444 Ontario Moses Alan U of Toronto Brendan Frey Computational methods for image‐based proteomics Drug discovery, cell biology, proteomics Genomics 11445 Ontario Neufeld Josh U of Waterloo Andrew Doxey Metabolic and GeNomic Exploration Tool (MAGNET) Genome analysis, environment, human microbiome Genomics 11446 Ontario Parkinson John Sick Kids Accurate taxonomic partitioning of functions encoded by microbiomes Microbiomes; Community composition and function; Genomics Inflammatory Diseases; Bioremediation; Livestock production 11447 Ontario Perkins Theodore OHRI/U of Ottawa Bayesian Data Integration for Robust Personalized Medicine Personalized Medicine, Biomarker Discovery, Data Integration Genomics 11448 Ontario Pond Gregory McMaster Judith‐Anne W. Establishment of biostatistics framework for developing new human biomarkers Biostatistics, biomarkers, laboratory assessments Genomics Chapman and maintaining quality control 11449 Ontario Provart Nicholas U of Toronto Manuel Corpas A BioJS‐Powered Visualization Dashboard for Precision Genomic Medicine visualization, visual analytics, precision genomics, interoperability Genomics 11450 Ontario Genome BC Provart Nicholas U of Toronto Carl Douglas ePlants for Accessing and Integrating Multi‐Level ‘Omics Data for 15 systems biology, agriculture Genomics Agronomically‐Important Species for Hypothesis Generation 11451 Ontario Pugh Trevor PMCC, UHN Methods to infer cell types in tumour biopsies using public, large‐scale cancer genomics, immunotherapy, molecular pathology Genomics transcriptomics data 11452 Ontario Pugh Trevor PMCC, UHN Canadian Atlas of Single Cell Expression (CASCE) Cell biology, data‐sharing, gene expression Genomics 11453 Ontario Reimand Juri OICR Using networks to interpret variation in whole‐genome sequencing data Genome variation, network analysis, cancer drivers, functional Genomics analysis 11454 Ontario Rodrigue Nicolas Carleton U Modeling the departures from the mutation‐selection balance in DNA sequence Phylogenetics, molecular evolution, mutation‐selection balance, Genomics evolution amino acid constraints, adaptation 11455 Ontario Rogan Peter Western Luis Rueda Biochemically‐inspired machine learning to predict chemotherapy response in Chemotherapy, pharmacogenomics, bladder cancer, breast Genomics solid tumours cancer 11456 Ontario Ross Heather J. UHN Cedric Manlhiot Optimizing the usability and utilization of complex clinical and genomic data in a clinical care; decision support tools; predictive models; data Genomics clinical visualization 11457 Ontario Sankoff David University of Ottawa Algorithms, analyses and implementation of ancestral angiosperm genome Land plants, evolution, chromosome, paleopolyploidy, Genomics reconstruction, with a focus on agriculturally important genera and families rearrangements 11458 Ontario Shlien Sick Kids Algorithms for deep integration of whole genome and transcriptome data in RNA‐sequencing, integrative data analysis Genomics human cancer 11459 Ontario Simpson Jared OICR Rapid genome assembly using long read sequencing Bioinformatics, genomics, algorithms, sequence analysis, genome Genomics assembly 11460 Ontario Stein Lincoln OICR A protein structure‐based pathway and network analysis platform for genomic genomics, protein structure, Reactome, biological networks and Genomics data pathways 11461 Ontario Stein Lincoln OICR Paul Boutros Gene Network Methods for Molecular Biomarker Discovery Cancer, genome, biomarker, network, prognosis and drug‐ Genomics sensitivity 11462 Ontario Weaver Donald Toronto Western/UHN David Dyment An In Silico High Throughput Strategy for Genetic Epilepsies Computer‐aided drug design, in silico high throughput screening, Genomics drug repurposing, orphan indications, epilepsy 11463 Ontario Wong Andrew Waterloo WeMineTM on Cloud: A Pattern Discovery Tool to Reveal Functionality, Discover Biosequence analysis; Proteomics; Protein‐Protein Interactions; Genomics Biomarkers and Predict Interactions in Biosequences Protein‐ DNA Interactions; Biomarkers Discovery 11464 Ontario Xu Wei UHN, PMCC Andrew Paterson Methodology Development and Implementation for Microbiome Data: Genetics and Genomics, Sequencing, Microbiome data, Genomics Hierarchical Modeling on Clustered Taxa Counts with Repeated Measures Environmental risk factors, taxonomic structure