The People Make the Place Annual Review 2008
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Complete Concerts and Recording Sessions Brighton Festival Chorus 27 Apr 1968 Concert Dome Concert Hall, Brighton Brighton Festival Belshazzar's Feast Walton William Walton Royal Philharmonic Orchestra Baritone Thomas Hemsley 11 May 1968 Concert Dome Concert Hall, Brighton Brighton Festival Kyrie in D minor, K 341 Mozart Colin Davis BBC Symphony Orchestra 27 Oct 1968 Concert Dome Concert Hall, Brighton Brighton Philharmonic Society Budavari Te Deum Kodály Laszlo Heltay Brighton Philharmonic Orchestra Soprano Doreen Price Mezzo-Soprano Sarah Walker Tenor Paul Taylor Bass Brian Kay 23 Feb 1969 Concert Dome Concert Hall, Brighton Brighton Philharmonic Society Symphony No. 9 in D minor, op.125 Beethoven Herbert Menges Brighton Philharmonic Orchestra Soprano Elizabeth Harwood Mezzo-Soprano Barbara Robotham Tenor Kenneth MacDonald Bass Raimund Herincx 09 May 1969 Concert Dome Concert Hall, Brighton Brighton Festival Mass in D Dvorák Václav Smetáček Czech Philharmonic Orchestra Soprano Doreen Price Mezzo-Soprano Valerie Baulard Tenor Paul Taylor Bass Michael Rippon Sussex University Choir 11 May 1969 Concert Dome Concert Hall, Brighton Brighton Festival Liebeslieder-Walzer Brahms Laszlo Heltay Piano Courtney Kenny Piano Roy Langridge 25 Jan 1970 Concert Dome Concert Hall, Brighton Brighton Philharmonic Society Requiem Fauré Laszlo Heltay Brighton Philharmonic Orchestra Soprano Maureen Keetch Baritone Robert Bateman Organ Roy Langridge 09 May 1970 Concert Dome Concert Hall, Brighton Brighton Festival Mass in B Minor Bach Karl Richter English Chamber Orchestra Soprano Ann Pashley Mezzo-Soprano Meriel Dickinson Tenor Paul Taylor Bass Stafford Dean Bass Michael Rippon Sussex University Choir 1 Brighton Festival Chorus 17 May 1970 Concert Dome Concert Hall, Brighton Brighton Festival Fantasia for Piano, Chorus and Orchestra in C minor Beethoven Symphony No. -
Trustees' Annual Report and Financial Statements 31 March 2016
THE FRANCIS CRICK INSTITUTE LIMITED A COMPANY LIMITED BY SHARES TRUSTEES’ ANNUAL REPORT AND FINANCIAL STATEMENTS 31 MARCH 2016 Charity registration number: 1140062 Company registration number: 6885462 The Francis Crick Institute Accounts 2016 CONTENTS INSIDE THIS REPORT Trustees’ report (incorporating the Strategic report and Directors’ report) 1 Independent auditor’s report 12 Consolidated statement of financial activities 13 Balance sheets 14 Cash flow statements 15 Notes to the financial statements 16 1 TRUSTEES’ REPORT (INCORPORATING THE STRATEGIC REPORT AND DIRECTORS’ REPORT) The trustees present their annual directors’ report together with the consolidated financial statements for the charity and its subsidiary (together, ‘the Group’) for the year ended 31 March 2016, which are prepared to meet the requirements for a directors’ report and financial statements for Companies Act purposes. The financial statements comply with the Charities Act 2011, the Companies Act 2006, and the Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK (FRS102) effective 1 January 2015 (Charity SORP). The trustees’ report includes the additional content required of larger charities. REFERENCE AND ADMINISTRATIVE DETAILS The Francis Crick Institute Limited (‘the charity’, ‘the Institute’ or ‘the Crick) is registered with the Charity Commission, charity number 1140062. The charity has operated and continues to operate under the name of the Francis Crick -
Staff Changes Emma Bennett Joined the Academy As Exhibits Regularly in the UK and Europe
Council Election Nobel Prize Congratulations to the following Fellows who Dr Sydney Brenner were elected to serve as new members of FRS HonFMedSci was awarded The Council with effect from 21 November 2002. Nobel Prize in Physiology or Medicine for 2002 for his research into genetic regulation of organ development and Professor Carol Black programmed cell death. Though now based in California, President, The Royal College of Physicians and Professor of Sydney Brenner’s discoveries whilst working in Cambridge, Rheumatology, Royal Free and University College Medical School UK, laid the foundation for this year’s prize which was awarded jointly to H Robert Horvitz and John E Sulston. Professor Nancy Rothwell MRC Research Professor, University of Manchester Professor Julia Goodfellow Chief Executive, the Biotechnology and Biological Sciences Research Council Professor Colin Bird Sir Douglas Black Formerly Dean of Medicine and Provost of Faculty Group of Medical and Veterinary Medicine, University of Edinburgh Sir Douglas Black: died September 13, 2002. It is with Medical School much sadness that we record the passing of a distinguished Honorary Fellow. The Black report was widely Professor Jonathan Cohen regarded as the most authoritative publication on the link Dean, Brighton & Sussex Medical School between poor health and social deprivation. That it became Professor Thomas Kirkwood so influential was at least in part due to the then Professor of Medicine, University of Newcastle Upon Tyne Government’s efforts to suppress its publication. Council is pleased to announce the appointment of Sir John Skehel, Sir Douglas was a widely respected and much loved FRS FMedSci, as Shadow Vice-President with responsibility for Professor of Medicine at Manchester and later President of non-clinical affairs. -
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(~2C i ~c Co P / The Arts Council of Great Britai n Twenty fourth The Arts Council of Great Britai n s 105 Piccadilly annual report and account London W1 V OA U year ended 31 March 1969 01-629949 5 ARTS COUNCIL OF GREAT BRITAIN REFERENCE ONLY DO NOT REMOVE . FROM THE LIBRA] Membership of the council, committees and panels Council The Lord Goodman (Chairman ) Professor Sir William Coldstream, CBE, DLitt (Vice-Chairman ) The Hon . Michael Asto r Frederic R . Cox, OB E Colonel William Crawshay, DSO, T D Miss Constance Cumming s Cedric Thorpe Davie, OBE, LL D Peter Hall, CB E The Earl of Harewoo d Hugh Jenkins, M P Professor Frank Kermod e J. W. Lambert, DSC Sir Joseph Lockwoo d Colin H. Mackenzie, CMG DrAlun Oldfield-Davies, CB E John Pope-Hennessy, CB E The Hon . Sir Leslie Scarman, OB E George Singleton, CB E Sir John Witt Scottish Arts Counci l Colin H. Mackenzie, CMG (Chairman ) George Singleton, CBE (Vice-Chairman ) Neill Aitke n J . S . Boyl e Colin Chandler J. B . Dalby, OB E Cedric Thorpe Davie, OBE, LL D Professor T . A. Dun n David A . Donaldson, RSA, R P The Earl Haig, OB E Douglas Hall, FM A Clifford Hanley William Hannan, M P R . D . Hunter, MB E Ronald Macdonald Neil Paterso n Alan Reiach, OB E Professor D . Talbot Rice, CBE, TD, DLitt, FS A Dame Jean Roberts, DBE, DL, J P Alan Roger Ivison S . Wheatley Thomas Wilso n Welsh Arts Counci l Colonel William Crawshay, DSO, TD (Chairman ) Alex J . -
Life Changing Science
LIFE CHANGING SCIENCE The Francis Crick Institute Annual Review 2017/18 AN INSTITUTE FOR DISCOVERY Our commitment to excellence, our emphasis on multidisciplinary research, our focus on young and emerging talent and our novel ways of partnership working are some of the factors that set the Crick apart. Front cover Vaccinia virus infection (green) disrupts a layer of epithelial cells (red/blue). Courtesy of Michael Way, Group Leader at the Crick. INTRODUCTION 2 Who we are Our year at a glance 2 Introduction by Paul Nurse 4 The Francis Crick Institute is a biomedical Progress against our strategy 6 discovery institute dedicated to understanding the RESEARCH HIGHLIGHTS 10 Cancer-causing mutation fundamental biology underlying health and disease. suppresses immune system 11 Our work is helping to build an understanding of Predicting lung cancer’s return 12 New understanding of human why disease develops and to translate discoveries embryo development 14 Chemical attraction could improve into new ways to prevent, diagnose and treat cancer immunotherapy 16 illnesses such as cancer, heart disease, stroke, Genes linked to malaria parasites’ persistence 17 infections and neurodegenerative diseases. Architecture of our ‘second brain’ 18 Cause of infertility side-stepped in mice 19 Mechanism for spinal cord development discovered 20 A new layer of complexity in embryo development 21 Two DNAs wedded with this ring 22 Unravelling how DNA gets copied 23 Telomerase’s dark side discovered 24 REVIEW OF THE YEAR 26 New group leaders arrive 27 Joined-up thinking 30 Focusing on the molecules of life 32 CryoEM at the Crick 34 Bringing academia and industry closer together 36 The people making research happen 38 Patterns in art and science 40 Rewarding research 42 Appointments 43 Supporting new discoveries 44 Our vision What’s inside Our vision is to be a world- We bring together outstanding scientists Science feature 32 leading multidisciplinary from all disciplines and carry out research Sophisticated microscopy is being biomedical research institute. -
ITMAT 11 Annual International Symposium Monday and Tuesday, October 17-18, 2016 Perelman School of Medicine, University of Penns
ITMAT 11th Annual International Symposium Monday and Tuesday, October 17-18, 2016 Perelman School of Medicine, University of Pennsylvania Smilow Center for Translational Research (SCTR) The Arthur Rubenstein Auditorium 3400 Civic Center Boulevard, Philadelphia, PA Translational Science in the Era of Precision Medicine Monday, October 17 (Day 1) 8:00 AM Registration and Breakfast: Smilow Lobby 8:45 Introduction J. Larry Jameson, MD, PhD, Executive Vice President, University of Pennsylvania for the Health System, and Dean, Perelman School of Medicine, University of Pennsylvania Session 1: Precision Medicine Initiatives at Scale Session Chairs: Sir Keith Peters, FRCP, FRS, FMedSci, Emeritus Regius Professor of Physic, University of Cambridge, Consultant in Clinical Science and Translational Medicine to the Francis Crick Institute and Senior Consultant in R&D to GlaxoSmithKline and Jonathan A. Epstein, MD, Executive Vice Dean and Chief Scientific Officer, Perelman School of Medicine, University of Pennsylvania 9:00 Genes, Genomes and the Future of Medicine Richard Lifton, MD, PhD, President, Rockefeller University 9:30 Precision Medicine and Global Health Ezekiel J. Emanuel, MD, PhD, Vice Provost for Global Initiatives, Chair, Department of Medical Ethics and Health Policy, University of Pennsylvania 10:00 Precision Medicine in the UK: from 100,000 Whole Genomes to 65 Million Patients Professor Sir John Savill, MB ChB, PhD, FRS, Chief Executive, Medical Research Council UK 10:30 COFFEE: Smilow Lobby Session 2: The Biology of Senescence Session Chairs: Virginia M.-Y. Lee, PhD, Professor of Pathology and Laboratory Medicine, Director, The Center for Neurodegenerative Disease Research at the Perelman School of Medicine of the University of Pennsylvania and Nancy M. -
Llio Evans SOPRANO
Llio Evans SOPRANO Welsh soprano, Llio Evans, gained a first-class honours degree at the Royal Welsh College of Music and Drama before going on to study with Dennis O'Neill at the Wales International Academy of Voice. A winner of numerous awards including Osborne Roberts Memorial Prize, Dame Anne Evans Award, and the Russell Sheppard Intercollegiate Award, Llio is a British Youth Opera and Welsh National Youth Opera alumna and a former Alvarez Young Artist at Garsington Opera where she was a recipient of the Leonard Ingrams Award. Delayed due to COVID-19, Llio returns to Longborough Festival Opera as Melanto Il ritorno d’Ulisse in patria in summer 2021. Highlights in recent season include Celia Iolanthe for English National Opera; Iris Semele for Garsington Opera; Zerlina Don Giovanni or Longborough Festival Opera; The Little One in the UK premiere of The Golden Dragon (Peter Eötvös) for Music Theatre Wales; and the soprano role in Waxwings for English Touring Opera. She also sang the soprano solo in Janáček The Danube with the BBC National Orchestra of Wales. Operatic roles include Clorinda La Cenerentola (HighTime Opera); Blonde Die Entführung aus dem Serail (Pop-Up Opera); Yum-Yum The Mikado, Gretel Hansel and Gretel (Co-Opera Co.); and Susanna The Marriage of Figaro and Pamina The Magic Flute (Opera’r Ddraig). Roles understudied include Despina Così fan tutte and Mimi Vert-Vert (Garsington Opera); and Ilia Idomeneo (English Touring Opera). A regular on the concert platform, highlights include Mendelssohn Elijah (St John's Smith Square, Three Choirs Festival with Philharmonia Orchestra), Bach Schweigt stille, plaudert nicht (Ensemble Cymru) and Arwel Hughes' Gweddi with the BBC National Orchestra of Wales conducted by Owain Arwel Hughes for BBC Radio 3. -
1 TREORCHY Ramah Chapel JHD TJ 2 PENTRE St Peter's Church JHD
1947 TOTAL NO DATE VENUE ARTISTS REMARKS PROCEEDS CHOIR CON ACC AUD 1 1 Sun July TREORCHY Cas Powell, Jack A collection of £12 made for Choir Funds JHD TJ 20 Hughes, D. Davies, choir funds – the start of a Ramah Chapel Eddie Hughes glorious future! 2 2 Sun July PENTRE Olive Jones & organists A £2.2.0 from the church to Choir Funds JHD TJ 27 Nancy Dotter, Myra choir funds St Peter’s Church Lewis, Bryn Howells 3 3 Sun Aug CWMPARC Leslie Edwards, Idris A £7 collection for the choir Choir Funds JHD TJ 10 Higgon, Tom Griffiths. funds Salem Chapel Eddie Hughes 4 4 Mon PORTHCAWL Hilda Edwards, Idris The first “away” concert JHD TJ Sept 14 Higgon, Eddie Hughes. The Pavilion D. Davies 5 5 Sun Dec TREORCHY Hilda Edwards, Idris Organised by the Chapel JHD TJ 9 Higgon, D. Davies Fellowship Bethlehem Chapel 1948 TOTAL NO DATE VENUE ARTISTS REMARKS PROCEEDS CHOIR CON ACC AUD 6 1 Sun TREORCHY Linda Parker, William The Choir’s First Celebrity JHD TJ April 1 Parsons Concert Bethlehem Chapel Sat May Adjudicators Dr The Whitsun Eisteddfod. £20 won for 7 2 TREORCHY nd JHD TJ 18 Sumpsion & Ivor Owen Awarded 2 Place (behind Choir Funds Parc & Dare Hall Pendyrus) on Nidaros Sat June Adjudicator: Prof Semi-National Eisteddfod. £40 won for 8 3 LLANHARAN st JHD TJ 26 Joseph Lewis Awarded 1 Place for Choir Funds Eisteddfod Field (Guildhall School Mus) performance of Nidaros 9 4 Sun TREHERBERT Miss Bick, Tom £10 to church JHD TJ June 27 Griffiths, Idris Higgon funds Blaen-y-Cwm Chapel 10 5 Sun July TREORCHY Sam Griffiths, Haydn First appearance of Sam £15 to chapel JHD TJ 2 Parfitt, Master John Griffiths as choir soloist funds Ramah Chapel Hughes 11 6 Sun July CWMPARC W. -
Institute of Contemporary British History
Origins of the National Institute for Health Research Edited by Paul Atkinson and Sally Sheard Department of Public Health and Policy University of Liverpool © Department of Public Health and Policy, University of Liverpool. All rights reserved. This material is made available for personal research and study only. We give permission for this file to be downloaded for such personal use. For reproduction or further distribution of all or part of this file, permission must be sought from the copyright holder. Published by: Department of Public Health and Policy, University of Liverpool, 2018. ISBN: 978-1-9999209-3-7 Origins of the National Institute for Health Research Transcript of a Witness Seminar held at the University of Liverpool in London on 28 February 2018 Acknowledgements: The convenors would like to thank the witnesses for their contributions, and the staff at the University of Liverpool in London and Ubiqus for their support. Photographs: Department of Public Health and Policy, University of Liverpool. Contents Introduction…………………………………………………………………………………………p1 Contributors……………..………………………………………………………………………….p4 Areas for Discussion……...………………………………………………………………………...p6 Witness Seminar Transcript…………………………………………………………………….…..p8 Instructions for Citation This document has also been published online. References to this Witness Seminar should refer readers to the online version, following the format below: [Witness name], in The Origins of the National Institute for Health Research, held 28 February 2018 at the University of Liverpool in London, published by the Department of Public Health and Policy, University of Liverpool, 2018, https://www.liverpool.ac.uk/psychology-health-and- society/research/ governance-of-health/witness-seminars/ [page number of reference]. Introduction There has been publicly-funded health research in the UK for just over 100 years, but the idea that the National Health Service needs to commission some of it is only a generation old. -
Newsletter Monday 4Th March, 2019
Newsletter Monday 4th March, 2019 WORLD BOOK DAY Headteacher’s Welcome World Book Day is on Thursday WORLD-RENOWNED CONDUCTOR VISITS LEWKNOR 7th March this year and instead of asking the children to come to school dressed as their favourite book character, the teachers and I thought it would be a lovely idea to invite all parents / grandparents / nannies / childminders to school to read a story to their child and perhaps some other children. We thought it would be a good Famous conductor Owain Arwel Hughes, who way to end the school week so has worked with Pavarotti and has performed parents etc are invited to bring for the Queen, took time off from his busy a story book to school on schedule to visit the Upper Juniors. Friday 8th March from 2.30pm. If you are short on books or Mr Hughes talked about his extraordinary life ideas for a good story, we have performing all around the world and the plenty at school that you can children took notes (see picture below), which borrow. they later used when they wrote their biographies of the composer. If you would like to take part, please would you contact Vicky in the office so that we can organise the children in advance. Thank you. Top picture: Mr Hughes with the children in Upper Juniors Above left: Mr Hughes shows the children his box of batons LEWKNOR C of E PRIMARY SCHOOL HIGH STREET LEWKNOR OXFORDSHIRE OX49 5TH Head Teacher: Mrs D Cole Telephone: 01844 351542 E-mail: [email protected] Website: www.lewknor.eschools.co.uk Top left: The children busy at work taking notes about Mr Hughes’s life The children learned many fascinating facts about Mr Hughes, who is the grandfather of Elektra and Top right: Callum has a turn at conducting! Clemmy. -
Sergei Rachmaninov
BIS-CD-1279 STEREO D D D Total playing time: 67'59 RACHMANINOV, Sergei Vasilievich (1873-1943) Symphony No. 2 in E minor, Op.27 (1906-07) (Boosey & Hawkes) 67'21 1 I. Largo – Allegro moderato 25'08 2 II. Allegro molto 10'11 3 III. Adagio (solo clarinet: John Cushing) 16'09 4 IV. Allegro vivace 15'34 Royal Scottish National Orchestra (leader: Edwin Paling) conducted by Owain Arwel Hughes The Royal Scottish National Orchestra is supported in this recording project by The Royal Bank of Scotland. 2 t resurrexit. Ten years earlier Sergei Rachmaninov, the pride of the Moscow Conser- vatory, had experienced a complete fiasco with the première of his Symphony No.1 in E D minor, Op.13 – an event which caused him to fall silent as a composer for three years. Seven years earlier, the psychotherapeutic treatment he received from Nikolai Dahl, a doctor and amateur musician, had restored his creative courage. Six years earlier, he had re- conquered the concert stage with his Piano Concerto No. 2 in C minor, Op.18. The year was thus 1907; Russia was in the grip of revolutionary unrest, and Rachmaninov, having com- pleted a two-year period as conductor at the Bolshoi Theatre in Moscow, was in Dresden with his wife and children: only now did the 34-year-old composer face the trauma of a new sym- phony. His Symphony No. 2 in E minor, Op. 27, like the great majority of his works, is in a minor key; only in the third movement and – per aspera ad astra – in the finale does it break jubilantly into the major. -
Sir Edward William Elgar (1857 - 1934)
SIR EDWARD WILLIAM ELGAR (1857 - 1934) Symphony No. 2 in E flat major, Op. 63 [56.35] Symffoni Rhif 2 mewn E meddalnod Fwyaf, Op. 63 1 I Allegro vivace e nobilmente [19.00] 2 II Larghetto [14.15] 3 III Rondo (Presto) [8.20] 4 IV Moderato e maestoso [15.00] published by Edwin F. Kalmus & Co. ALUN HODDINOTT (b. 1929) Investiture Dances, Op. 66 [8-22] 5 I Allegro [2.32] 6 II Andante [3.36] 7 III Presto [2.14] published by Oxford University Press Total CD duration: [64.59] CERDDORFA GENEDLAETHOL IEUENCTID CYMRU NATIONAL YOUTH ORCHESTRA OF WALES Conducted by OWAIN ARWEL HUGHES EDWARD ELGAR (1857 - 1934) Symphony No 2 in E flat Major, Op. 63 1 Allegro vivace e nobilmente 2 Larghetto 3 Rondo (Presto) 4 Moderato e maestoso The premiere of Elgar's First Symphony was one his greatest triumphs and, in the year that followed, it went on to receive over one hundred performances. Consequently, it was with some confidence that Elgar looked forward to the premiere of his Second Symphony, two and a half years later. Yet at the premiere, conducted by the composer at Queen's Hall, London, on 24 May 1911, many of the seats were empty and its reception lacked enthusiasm. "What is the matter with them?" Elgar asked the orchestral leader, W.H. Reed, "They sit there like a lot of stuffed pigs." With hindsight, it is not difficult to understand the audience's reaction. The Second Symphony is one of Elgar's finest achievements, but it is also one of his most complex and ambivalent.