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Praglia-Padua, Italy, October 21-23, 2004

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Praglia-Padua, Italy, October 21-23, 2004 1st Biannual Meeting of the Congress Venue Abbazia di Praglia Via Abbazia, 7 ASSOCIATION Bresseo di Teolo, Padua, Italy for EUROPEAN CARDIOVASCULAR PATHOLOGY October 21-23, 2004 THURSDAY OCTOBER 21, 2004 PRESIDENT Anton E. Becker, Amsterdam-NL 09:00 VULNERABLE PLAQUE UNIVERSITY OF PADUA Plaques at high risk of myocardial infarction and sudden death A. Van der Wal, Amsterdam-NL PROGRAM COMMITTEE CHAIR Triggers and clinical markers of acute coronary syndromes Patrick J. Gallagher, Southampton-UK F. Crea, Roma-I In vivo detection of vulnerable plaque: invasive imaging A.N.M.C.O. R. De Caterina, Chieti-I LOCAL ORGANIZING COMMITTEE In vivo detection of vulnerable plaque: non invasive imaging J. Narula, Orange-USA Gaetano Thiene, chair Interventional treatment of acute coronary syndromes Annalisa Angelini E.S.C.-WG17 B. Reimers, Mirano Venezia-I Cristina Basso 12:15 Key note lecture Experimental Atherogenesis Fiorella Calabrese H-A. Lehr, Mainz-D University of Padua Medical 17:00 OPENING CEREMONY AND MASTER LECTURE School, Padua - I Aula Magna, Palazzo del Bo’ FACULTY OF MEDICINE, UNIVERSITY OF PADUA Therapeutic weapons against atherothrombosis V. Fuster, New York-USA FRIDAY OCTOBER 22, 2004 G.S.I.P.C. 09:00 HEART VALVE DISEASE Surgical anatomy of cardiac valves A. Cook, London-UK The current pathology spectrum of valve disease S.I.A.P.E.C.-I.A.P. P. Bruneval, Paris-F Clinical non–invasive assessment of heart valve disease: morphological and functional aspects R. Scognamiglio, Padua-I Surgical treatment: valve repair S.I.C. O. Alfieri, Milan-I Surgical treatment: valve replacement and outcome G. Gerosa, Padua-I ORGANIZING SECRETARIAT 17:00 Key note lecture Advances in cardiovascular imaging A.R.C.A. R. Fattori, Bologna-I Associazione Ricerche Cardiopatie Aritmiche SATURDAY OCTOBER 23, 2004 Chiara Carturan Via A. Gabelli, 86 09:00 STEM CELLS Joint Symposium of the Association for European Cardiovascular 35121 Padua - I Pathology and Society for Cardiovascular Pathology Phone +39 049 8272286 Development of cardiac muscle cell diversity Fax +39 049 8272284 A. Moorman, Amsterdam-NL Human and mouse stem cells in repair of the injured heart: functional aspects e-mail: [email protected] Ministero della Salute C. Murry, Seattle-USA website: http://anpat.unipd.it/ARCA/ Endothelial and smooth muscle progenitor cells and their roles in tissue regeneration R.N. Mitchell, Boston-USA TRAVEL AGENCY For Italian Participants Only Factors affecting functional outcome after autologous skeletal myoblast PETRARCA TOURS The Meeting has been transplantation Cristina Da Valle registered for Continuing J-T. Vilquin, Paris-F Piazza Eremitani, 3 Infarct remodelling after intramyocardial progenitor cell injection treatment in Medical Education 35121 Padua - I of the Italian Ministry of patients with acute myocardial infarction Health and obtained 16 C. Stamm, Rostock-D Phone +39 049 654788 credit hours. Number of 12:30 Key note lecture Molecular genetics of sudden death Fax +39 049 8750938 participants is limited to 50. G.A.Danieli, Padua-I e-mail: [email protected] with support of: CONTENTS Welcome Message page 05 AECVP Council 07 con General Information 08 Social Programme 09 ten Scientific Programme 10 Business Meeting 15 Abstracts 17 ts Contributors 103 3 WELCOME MESSAGE It is a great pleasure to welcome the European scientists working in presi wel the field of cardiovascular pathology. The Association for European PRESIDENT Anton E. Becker, Amsterdam-NL Cardiovascular Pathology, recently founded, will held in the Abbey of Praglia the first biannual Meeting, with 3 days of full immersion of Symposia, Free communications and Posters. A Joint Symposium has dent co been planned with the Society for Cardiovascular Pathology, which is PROGRAM COMMITTEE CHAIR the “sister” society on the other side of the Atlantic Ocean. Patrick J. Gallagher, Southampton-UK It is particularly a great honour for the University of Padua to give hospitality to this scientific event, considering that anatomy, phisiology organ me and pathology of the heart and great vessels first developed in this old gymnasium in the XVI-XVIII centuries, thanks to the contributions of LOCAL ORGANIZING COMMITTEE Andreas Vesalius, William Harvey and Giovanni Battista Morgagni. The tradition of the study and treatment of cardiovascular diseases izingGaetano Thiene, chair me culminated recently in the heart transplantation, carried out in Padua Annalisa Angelini for the first time in Italy in 1985, which resulted in the turning of the Cristina Basso role of the cardiac pathologist from postmortem to in vivo investigation. traveFiorella Calabrese ssa Pathology evolved tremendously in the last decades with the advent University of Padua Medical School, Padua- I of immunohistochemistry and molecular biology, to play a crucial role both in the care of the patient and in basic science research. Keeping the pace of clinical advances represents the major challenge for the lagen ge pathologist, especially in the field of cardiovascular diseases which are the major causes of morbility and mortality in the Western countries. I wish all the attendants stimulating and fruitfull scientific debates as well as a pleasant stay in the Euganei Hills of Francesco Petrarca and cy ORGANIZING SECRETARIAT Tito Livio. A.R.C.A. Associazione Ricerche Cardiopatie Aritmiche Ms Chiara Carturan Via A. Gabelli, 86 Gaetano Thiene 35121 Padua-I Chairman, Phone +39 049 8272286 Local Organizing Committee Fax +39 049 8272284 e-mail: [email protected] website: http://anpat.unipd.it/ARCA/ TRAVEL AGENCY PETRARCA TOURS Ms Cristina Da Valle Piazza Eremitani, 3 35121 Padua-I Phone +39 049 654788 Fax +39 049 8750938 e-mail: [email protected] 5 AECVP COUNCIL OFFICERS Anton E. Becker , Amsterdam-NL President Gaetano Thiene, Padua-I Vice-President aec Allard C. van der Wal, Amsterdam-NL Secretary Treasurer COUNCIL MEMBERS Mark Kockx, Antwerp-B vpc Hans-Anton Lehr, Mainz-D oun Patrick Bruneval, Paris-F STANDING COMMITTEES Educational Committee cil Patrick J. Gallagher, Southampton-UK Chair Chris Ihling, Frankfurt-D C. James Kirkpatrick, Mainz-D Membership Committee Annalisa Angelini, Padua-I Chair Michiel Knaapen, Antwerp-B Simon Kim Suvarna, Sheffield-UK Nominating Committee Margaret Burke, Harefield-UK Chair Ulrik Baandrup, Aarhus-DK Mat J.A.P. Daemen, Maastricht-NL 6 7 GENERAL INFORMATION DATES and VENUE: From Thursday 21 October to Saturday 23 October 2004. BADGES: Name badges will be needed for admission to the scientific sessions. Please, wear your badge visibly. The Meeting will take place in the Benedictine Abbey of Praglia, that lies at the foot of the Euganean Hills, 12 km DELEGATE BRIEFCASES: Please ensure that your briefcase is clearly labelled with assocfrom Padua. your name or business card. How to reach Praglia CERTIFICATE of ATTENDANCE: Certificate of attendance will be available at the It is easily accessible by car and bus service. Registration Desks on Saturday 23 October. iationThe Venice-Marco Polo Airport is close to Padua approximately 30 minutes and the most convenient way to TRANSFER SERVICE: During the days of the meeting, transfer service will be reach the Congress venue is by using the bus service. provided to the registered participants by bus from Abano – from Venice Airport: take the bus ACTV for Teolo (that Terme to Praglia in the morning and back to Abano Terme for stop also at the Padua station). at the end of each daily programme. More information will – from Padua Railway Station: 5 minutes walk to the SITA be available at the Secretariat Desk during the meeting. Bus Station, take the bus for Teolo-Vò-Noventa Vicentina (bus stop: Praglia) CLIMATE: The temperature in October is approximately 15°C in the europOtherwise, by car: daytime, but cooler at night. – from Venice: highway A4 Milano-Venezia, Padova Ovest exit. Proceed toward Terme Euganee and then to Colli SOCIAL PROGRAM: Thursday, October 21, 2004 – h. 17:00 Euganei (km.18); Visit to Palazzo del Bo’ and Anatomical Theatre waived ean – from Bologna: highway A13 Padova-Bologna, Terme Euganee exit, toward Montegrotto Terme, Colli Euganei, Friday, October 22, 2004 – h. 21:00 Monterosso (km.14) Congress Dinner euro 50 cardioOFFICIAL LANGUAGE: The official language of the Meeting is English. POST-CONGRESS PROGRAM: Sunday, October 24, 2004 Tour to Venice Laguna Islands REGISTRATION FEE: Members waived and lunch at the Cipriani Locanda in Torcello euro 120 Non members Euro 120 vascuYoung investigators (<35 yrs) waived Lunch is not included in the registration fee, that will cost Euro 25 each larACCREDITATION: The meeting has been registered for Continuing Medical Education of the Italian Ministry of Health and obtained 16 credit hours. FOR ITALIAN L’accreditamento è stato richiesto per la sola categoria dei pathomedici per un numero limitato di 50 partecipanti. Ai fini PARTICIPANTS ONLY: dell’attestazione dei crediti formativi ECM è necessaria l’effettiva presenza al 100% di tutte e tre le giornate con riconsegna al termine del congresso della documentazione logy debitamente compilata e firmata. La rilevazione della pre- senza avverrà tramite firma su modulo cartaceo disponibile presso il Desk Segreteria. 8 9 THURSDAY OCTOBER 21, 2004 THURSDAY OCTOBER 21, 2004 09:00 Registration P06 Late results on survival and rehospitalization in patients undergoing different treatment for severe ischemic mitral regurgitation with multivessel coronary SYMPOSIUM VULNERABLE PLAQUE artery disease (P.Buja, G.Tarantini, F.DelBianco, M.Napodano, G.Isabella, Chairpersons: A.E. Becker, Amsterdam-NL; S. Iliceto, Padua-I R.Razzolini, A.Ramondo, G.Gerosa, S.Iliceto; Padua-I) P07 Alveolar gas exchange improvement in prevention of adrenaline-induced 10:00 Plaques at high risk of myocardial infarction and sudden death S01 myocardial injury (V.A.Ohanyan, A.B.Semerjyan; Yerevan-AR) A. Van der Wal, Amsterdam-NL P08 Myocardial production and secretion of chromogranin A in hypertrophic cardiomyopathy (M.Pieroni, C.Chimenti, A.Santagostino, A.Maseri, A.Corti, 10:20 Triggers and clinical markers of acute coronary syndromes S02 A.Frustaci; Milan-I, Rome-I) F.
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