Id: 41 Autor: Bacellar, Renato Clark. Título: Brazil's Contribution to Tropical Medicine and Malaria: Personalities and Institutions

Total Page:16

File Type:pdf, Size:1020Kb

Id: 41 Autor: Bacellar, Renato Clark. Título: Brazil's Contribution to Tropical Medicine and Malaria: Personalities and Institutions 1/21 Id: 41 Autor: Bacellar, Renato Clark. Título: Brazil's contribution to tropical medicine and malaria: personalities and institutions. Fonte: Rio de Janeiro; s.n; 1963. 377 p. il. (Col. P. G). Símbolo: Col. P. G. Resumo(s): Relata os progressos da Medicina no Brasil, desde a descoberta do Pais em 1500, enfocando o aparecimento de instituicoes e escolas medicas - Instituto Adolfo Lutz, Instituto Butantan, Escola de Manguinhos, Escola Baiana,etc. Aponta ainda importantes vultos da Historia da Medicina Brasileira tais como Adolfo Lutz, Vital Brasil, Oswaldo Cruz e outros. Apresenta uma breve historia da febre amarela no Brasil e a contribuicao brasileira ao estudo da malaria.(MAM) - Pt Descritores: MEDICINA TROPICAL/história MALARIA/história ACADEMIAS E INSTITUTOS/história PESQUISADORES/história -BRASIL HISTORIA DA MEDICINA Descritores Locais: INSTITUTO OSWALDO CRUZ INSTITUTO ADOLFO LUTZ INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO INSTITUTO BUTANTAN Tipo de publicação: BIOGRAFIA Localização: BR1273.1; 610.9, B121b, Col. P. G Região não DeCS: SAO PAULO; RIO DE JANEIRO 2/21 Id: 10822 Autor: Portugal, Henrique Furtado. Título: Vital Brazil (1865-1950): subsídios para a biografia Vital Brazil / Vital Brazil (1865-1950): contributions to biography Vital Brazil. Fonte: São Paulo; Edições Movimento-Perspectiva; 1965. 104 p. Resumo(s): Coletânea de documentos e trechos extraídos da "Memória Histórica do Instituto Butantan" e dos "Anais Paulistas de Medicina e Cirurgia", sobre a história do ofidismo no Brasil, o surgimento do Instituto Butantan e sobre a vida e obra de Vital Brasil. Fundador do Instituto Butantan, descobridor do soro anti-ofídico, Vital Brasil nasceu em Minas Gerais na cidade de Campanha em 1865 e faleceu em Säo Paulo em 1950. A coletânea, patrocinada pelo governo de Minas Gerais, objetiva a divulgaçäo das fontes principais, sobre a obra do cientista mineiro, em homenagem ao centenário de seu nascimento.(JGC) - Pt Descritores: Saúde Pública/historia Academias e Institutos/historia Soros imunes/historia Leis Decretos -Brasil Descritores Locais: Instituto Butantan Ofidismo Tipo de publicação: BIOGRAFIA Localização: BR1273.1; 614.0981, P853v Indivíduo como tema: Brazil, Vital 3/21 Id: 9857 Autor: Teixeira, Luiz Antonio. Título: The Oswaldo Cruz Institute and its relationship with other biomedical research centers in Säo Paulo. Fonte: Parassitologia;47(3-4):345-351, Dec. 2005 . Resumo(s): It deals with the relationships between the Oswaldo Cruz Institute, a biomedical institution which was founded in Rio de Janeiro (Brazil) in the beginning of the 20th century, and other similar institution s founded in Säo Paulo during the same period, especially the Butantan and the Biological Institutes. The analyses comprehends the three first decades of the 20th century.(AU) - En Descritores: Ciência/história Saúde Pública/história História da Medicina -Brasil Descritores Locais: INSTITUTO OSWALDO CRUZ INSTITUTO BUTANTAN Localização: BR1273.1 4/21 Id: 9603 Autor: Fonseca Filho, Olympio da. Título: Primórdios da microscopia óptica no Brasil: alguns pioneiros / The origins of optical microscopy in Brazil: some pioneers Fonte: J. bras. med;14(2):131-134, fev. 1968. Resumo(s): Recorda os primeiros passos do emprego do microscópio como fundamento científico da nossa medicina clínica e experimental. Lembra que no Brasil se fizeram talvez as primeiras tentativas de introduçäo da técnica da microtomia, no começo do século passado, na época de Von Martius para quem o Baräo de Capanema construiu o primeiro micrótomo de que se tem notícia. Relata o nome de alguns dos pioneiros, lembra o nascimento das Escolas de Manguinhos, do Instituto Butantä e a açäo dos pesquisadores da Bahia. (AU) - En Descritores: Microscopia/história Medicina Clínica/história História da Medicina -Brasil Ciência/história Descritores Locais: INSTITUTO BUTANTAN INSTITUTO OSWALDO CRUZ Localização: BR1273.1 Região não DeCS: RIO DE JANEIRO, RJ 5/21 Id: 9532 Autor: Bertolli Filho, Cláudio. Título: Cultura institucional e história: o Instituto Butantan / Institutional culture and history: the Instituto Butantan Fonte: Cadernos de História da Ciência;11(1):145-166, jan./jun. 2005. Resumo(s): Coloca em tela a potencialidade do estudo da cultura das instituições, tendo como pano de fundo o Instituto Butantan.(AU) - Pt Descritores: Academias e Institutos/história Academias e Institutos/organizaçäo & administraçäo -dCiência/história Saúde Pública/história Brasil Descritores Locais: INSTITUTO BUTANTAN Localização: BR1273.1 6/2 1 Id: 9531 Autor: Ibañez, Nelson; Fan Hui Wen; Fernandes, Suzana C. G. Título: Instituto Butantan: história institucional - desenho metodológico para uma periodizaçäo preliminar / Instituto Butantan: institutional history - a methodological design for a preliminary periodization Fonte: Cadernos de História da Ciência;11(1):115-144, jan./jun. 2005. Resumo(s): A partir do evolver histórico do Instituto Butantan no século XX, em Säo Paulo, propõe um desenho metodológico para elaboraçäo de uma periodizaçäo preliminar, para o estudo de sua história institucional.(AU) - Pt Descritores: Academias e Institutos/história Ciência/história Saúde Pública/história -Brasil Academias e Institutos/organizaçäo & administraçäo Descritores Locais: INSTITUTO BUTANTAN Localização: BR1273.1 7/21 Id: 9527 Autor: Canter, Henrique Moisés. Título: Museu Histórico: origem e memória / Historical Museum: origin and memory Fonte: Cadernos de História da Ciência;1(1):63-81, jan./jun. 2005. Resumo(s): Apresenta a construçäo e a atuaçäo do Museu Histórico e a recuperaçäo do acervo de interesse institucional, com o objetivo de resgatar o esforço em recuperar parte da história do Instituto Butantan.(AU) - Pt Descritores: Museus/história Academias e Institutos/história -Brasil Saúde Pública/história Ciência/história Descritores Locais: INSTITUTO BUTANTAN MUSEU HISTÓRICO Localização: BR1273.1 8/21 Id: 9466 Autor: Sant´Anna, Oswaldo Augusto. Título: O espelho partido / The broken mirror Fonte: Cadernos de História da Ciência - Instituto Butantan;Cadernos de História da Ciência - Instituto Butantan;11(1): 50-60, jan. jun. 2005. Resumo(s): Reflexäo sobre produçäo de conhecimento em instituições de pesquisa que utiliza a biologia celular como modelo para ilustrar conceitos como memória e organicidade, examinando-se a lógica celular como mínima identidade da vida, ampliada para os organismos e as instituições.(AU) - Pt Descritores: Ciência/história História da Medicina -Brasil Saúde Pública/história Descritores Locais: INSTITUTO BUTANTAN Localizaçã o: BR1273.1 9/21 Id: 9465 Autor: Prado, José Amaral do. Título: Etapas da produçäo da vacina antivariólica no Instituto Butantan / Phases in the production of the vaccine against smallpox in the Instituto Butantan Fonte: Cadernos de História da Ciência - Instituto Butantan;Cadernos de História da Ciência - Instituto Butantan;11(1):27-33, jan. jun. 2005. Resumo(s): Resgate iconográfico das técnicas de produçäo da vacina antivariólica no Instituto Butantan.(AU) - Pt Desc ritores: Vacina Antivariólica/história Varíola/prevençäo & controle -Brasil Saúde Pública/história Ciência/história Descritores Locais: INSTITUTO BUTANTAN Localização: BR1273.1 Região não DeCS: SÃO PAULO, ESTADO 10 /21 Id: 9464 Autor: Soares, Murilo A; Solosando, Aline. Título: Apontamentos acerca da luta contra a varíola / Notes on smallpox control Fonte: Cadernos de História da Ciência - Instituto Butantan;1(1):13-26, jan. jun. 2005. Resumo(s): Apresenta uma recuperaçäo histó rica da varíola e sua trajetória no Brasil até a erradicaçäo na década de 80.(AU) - Pt Descritores: Varíola/prevençäo & controle Política de Saúde/história Vacina Antivariólica/história -Saúde Pública/história Brasil Ciência/história Descritores Locais: INSTITUTO BUTANTAN Localização: BR1273.1 Região não DeCS: SÃO PAULO, ESTADO 11/21 Id: 9116 Autor: Gadelha, Carlos; Azevedo, Nara. Título: Inovaçäo em vacinas no Brasil: experiência recente e constrangimentos estruturais / Vaccine innovations in Brazil: recent experiences and structural constraints Fonte: Hist. cienc. saude;10(supl.2); 697-724, 2003. Resumo(s): Oferece elementos para a discussäo atual sobre inovaçäo focalizando duas experiências na história de nosso desenvolvimento científico e tecnológico: as vacinas contra a hepatite B (HB) e contra a meningite (Haemophilus influenzae tipo b- Hib), geradas, respectivamente, no Instituto Butantan e em Bio-Manguinhos, unidade técnico-científica da Fundaçäo Oswaldo Cruz(FIOCRUZ) responsável pela produçäo industrial de imunobiológicos. A análise dessas experiências oferece balizamentos críticos para a reflexäo sobre o desenvolvimento científico e tecnológico na área de vacinas, bem como sobre o papel das lideranças e modelos institucionais adotados até o presente, sugerindo-se a necessidade de elaboraçäo de uma nova política de C&T capaz de superar as barreiras da dependência e construir uma capacitaçäo tecnológica local como fonte básica de competitividade e desenvolvimento em saúde.(AU) - Pt Nota Interna: Inclui bibliografia Descritores: VACINAS/provisäo & distribuiçäo DESENVOLVIMENTO TECNOLOGICO PROGRAMAS DE IMUNIZAÇAO POLITICA DE SAUDE -BRASIL Descritores Locais: INSTITUTO BUTANTAN FUNDAÇAO OSWALDO CRUZ BIO-MANGUINHOS Localização: BR1273.1 12/21 Id: 8733 Autor: Teixeira, Luiz Antonio. Título: Repensando a história do Instituto Butantan / Rethinking about the history of Instituto Butantan Fonte: In: Dantes, Maria Amélia M.Espaços da ciência no Brasil: 1800-1930. Rio de Janeiro, FIOCRUZ, 2001., il. Resumo(s): Tata
Recommended publications
  • Impact of the Household Environment Risk for Maintenance of Natural Foci
    medRxiv preprint doi: https://doi.org/10.1101/2021.05.18.21257380; this version posted May 22, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license . 1 Impact of the household environment risk for maintenance of natural foci of Leishmania infantum transmission to human and animal hosts in endemic areas for visceral leishmaniasis in Sao Paulo State, Brazil Patricia Sayuri Silvestre Matsumoto1, Roberto Mitsuyoshi Hiramoto2 Virgínia Bodelão Richini Pereira3 Valéria Medina Camprigher4, Helena Hilomi Taniguchi5, José Eduardo de Raeffray Barbosa6, Luiz Ricardo Paes de Barros Cortez7, Elivelton da Silva Fonseca8, Raul Borges Guimarães9 and José Eduardo Tolezano10* 1 Parasitology and Mycology Center, Adolfo Lutz Institute (IAL), Sao Paulo, Sao Paulo, Brazil; [email protected] 2 Parasitology and Mycology Center, Adolfo Lutz Institute (IAL), Sao Paulo, Sao Paulo, Brazil; [email protected] 3 Adolfo Lutz Institute, Regional Laboratories Center II Bauru, Bauru, Sao Paulo, Brazil; [email protected] 4 Center for Zoonoses Control of Bauru. Health Secretariat of Bauru; [email protected] 5 Parasitology and Mycology Center, Adolfo Lutz Institute (IAL), Sao Paulo, Sao Paulo, Brazil; [email protected] 6 Bioterium nucleos, Adolfo Lutz Institute (IAL), Sao Paulo, Sao Paulo, Brazil; [email protected] 7 Center for Zoonoses Control of Bauru.
    [Show full text]
  • Migration and Tuberculosis Transmission in A
    Pescarini et al. BMC Medicine (2018) 16:62 https://doi.org/10.1186/s12916-018-1055-1 RESEARCH ARTICLE Open Access Migration and tuberculosis transmission in a middle-income country: a cross-sectional study in a central area of São Paulo, Brazil Julia Moreira Pescarini1,3*, Vera Simonsen2, Lucilaine Ferrazoli2, Laura C. Rodrigues3, Rosangela S. Oliveira2, Eliseu Alves Waldman1† and Rein Houben3,4† Abstract Background: Little is known about the impact of growing migration on the pattern of tuberculosis (TB) transmission in middle-income countries. We estimated TB recent transmission and its associated factors and investigated the presence of cross-transmission between South American migrants and Brazilians. Methods: We studied a convenient sample of cases of people with pulmonary TB in a central area of São Paulo, Brazil, diagnosed between 2013 and 2014. Cases with similar restriction fragment length polymorphism (IS6110- RFLP) patterns of their Mycobacterium tuberculosis complex isolates were grouped in clusters (recent transmission). Clusters with both Brazilian and South American migrants were considered mixed (cross-transmission). Risk factors for recent transmission were studied using logistic regression. Results: Isolates from 347 cases were included, 76.7% from Brazilians and 23.3% from South American migrants. Fifty clusters were identified, which included 43% South American migrants and 60.2% Brazilians (odds ratio = 0.50, 95% confidence interval = 0.30–0.83). Twelve cross-transmission clusters were identified, involving 24.6% of all clustered cases and 13.8% of all genotyped cases, with migrants accounting for either an equal part or fewer cases in 11/12 mixed clusters. Conclusions: Our results suggest that TB disease following recent transmission is more common among Brazilians, especially among those belonging to high-risk groups, such as drug users.
    [Show full text]
  • Vital Brazil E a Autonomia (Vital) Para a Educação Introdução Imagine Se
    Vital Brazil e a autonomia (vital) para a educação Sandra Delmonte Gallego Honda1 Universidade Nove de Julho - UNINOVE Resumo: O presente artigo tem o objetivo de explanar de forma sucinta a biografia de Vital Brazil e relacionar suas contribuições na medicina e na educação brasileira. A educação, conforme é sabido, sofre defasagens consideráveis no cerne de alunos de escolas públicas que almejam adentrar em cursos superiores considerados, ainda hoje, elitistas, tal qual a medicina, que nos serve de protagonista neste trabalho. Buscou-se, assim, conjugar a biografia de Vital Brazil com as colocações de Paulo Freire em "Pedagogia do Oprimido" (2010), concluindo que a autonomia e a perseverança do educando diante das opressões e obstáculos são de suma importância para a concretização e a construção do indivíduo. Palavras-chave: Educação brasileira; pedagogia do oprimido; Vital Brazil Abstract: This paper its purpose explain a summarized form the Vital Brazil's biography and relate to their contributions in medicine with the Brazilian education. The education, as is known, suffers considerable gaps at the heart of public school students that aims to enter in university courses considered, even today, such elitists which medicine that serves the protagonist of this paper. It attempted to thus combine the biography of Vital Brazil with the placement of Paulo Freire in "Pedagogy of the Oppressed" (2010) concluding that the autonomy and perseverance of the student in front of oppression and obstacles are of paramount importance to the implementation and construction of the individual. Keywords: Brazilian education; pedagogy of the oppressed; Vital Brazil Introdução "A única felicidade da vida está na consciência de ter realizado algo útil em benefício da comunidade”.
    [Show full text]
  • We Gratefully Acknowledge the Following Authors From
    We gratefully acknowledge the following Authors from the Originating laboratories responsible for obtaining the specimens, as well as the Submitting laboratories where the genome data were generated and shared via GISAID, on which this research is based. All Submitters of data may be contacted directly via www.gisaid.org Authors are sorted alphabetically. Accession ID Originating Laboratory Submitting Laboratory Authors EPI_ISL_1009676, EPI_ISL_1009677, Diagnósticos da América - DASA Instituto de Medicina Tropical de Sao Paulo Brazil-UK Centre for Arbovirus Discovery Diagnosis Genomics and Epidemiology (CADDE) Genomic Network - Instituto de Medicina Tropical EPI_ISL_1009678 EPI_ISL_1060880, EPI_ISL_1060899 CDL Laboratorio Santos e Vidal LTDA. Instituto de Medicina Tropical de Sao Paulo Brazil-UK Centre for Arbovirus Discovery Diagnosis Genomics and Epidemiology (CADDE) Genomic Network - Instituto de Medicina Tropical EPI_ISL_1068157 Laboratorio de Ecologia de Doencas Transmissiveis na Laboratorio de Ecologia de Doencas Transmissiveis na Valdinete Nascimento, Victor Souza, André Corado, Fernanda Nascimento, George Silva, Ágatha Costa, Debora Duarte, Karina Pessoa, Matilde Mejía, Amazonia, Instituto Leonidas e Maria Deane - Fiocruz Amazonia, Instituto Leonidas e Maria Deane - Fiocruz Luciana Gonçalves, Maria Júlia Brandão, Michele Jesus, Felipe Naveca on behalf of the Fiocruz COVID-19 Genomic Surveillance Network Amazonia Amazonia EPI_ISL_1079161 IAL Regional de Bauru Instituto Adolfo Lutz, Interdiciplinary Procedures Center, Claudio Tavares
    [Show full text]
  • COVID-19 in Latin America the Implications of the First Confirmed
    Travel Medicine and Infectious Disease xxx (xxxx) xxxx Contents lists available at ScienceDirect Travel Medicine and Infectious Disease journal homepage: www.elsevier.com/locate/tmaid COVID-19 in Latin America: The implications of the first confirmed case in Brazil ARTICLE INFO Keywords: 2019-New coronavirus COVID-19 SARS-CoV-2 Outbreak Transmission Latin America Over the past weeks the spread of the Coronavirus Disease 2019 passenger flights scheduled to 103 destinations in 30 countries, and52 (COVID-19), caused by the Severe Acute Respiratory Syndrome domestic flights, connecting not only with major cities in Latin America Coronavirus 2 (SARS-CoV-2) [1], has been steady in Asia and other but also with direct flights to North America, Europe, Africa andthe regions in the world. Latin America was an exception until February 25, Middle East (Dubai). There are also buses that offer a service to and 2020, when the Brazilian Ministry of Health, confirmed the first case. from the metropolitan centers of Paraguay, Argentina, Uruguay and This first case was a Brazilian man, 61 years-old, who traveled from Bolivia. Brazil also connects with the countries of Chile, Argentina and February 9 to 20, 2020, to Lombardy, northern Italy, where a sig- Bolivia through some rail connections. The main seaport of Brazil is in nificant outbreak is ongoing. He arrived home on February 21,2020, Rio de Janeiro, where many international cruises also arrive. Thus, over and was attended at the Hospital Albert Einstein in São Paulo, Brazil. At the course of the next few days, a significant expansion in the region this institution, an initial real-time RT-PCR was positive for SARS-CoV- would be possible.
    [Show full text]
  • CE122/14 (Eng.) 13 April 1998 ORIGINAL: ENGLISH
    122nd Session Washington, D.C. June 1998 Provisional Agenda Item 4.8 CE122/14 (Eng.) 13 April 1998 ORIGINAL: ENGLISH HANTAVIRUS Since 1993, when an outbreak of hantavirus pulmonary syndrome was detected for the first time in the southwestern United States of America, several outbreaks or sporadic cases have been notified in Argentina, Brazil, Canada, Chile, Paraguay, and Uruguay. Outbreaks of this disease produce high case-fatality rates and have aroused widespread fear in the affected communities and great concern among the national health authorities. In light of this situation, the 40th Directing Council of the Pan American Health Organization (September 1997) adopted a resolution (CD40.R14) calling on the Member States to strengthen the mechanisms for collaboration among the countries and promote information, education, and communication geared toward the community to ensure the adoption of good environmental sanitation practices. That same resolution requests the Secretariat to create a task force to issue recommendations on surveillance, diagnosis, treatment, and prevention of the infection. The task force met in March 1998 to review and approve the guidelines on hantavirus. This document summarizes the historical background and current epidemio- logical situation of hantavirus infection. It also reports on PAHO activities to date in this area and presents a proposal for ongoing activities. The Executive Committee is requested to review this document and to make recommendations on the progress of the surveillance and detection activities
    [Show full text]
  • Yellow Fever in Rio De Janeiro and the Pasteur Institute Mission (1901-1905): the Transfer of Science to the Periphery
    Medical History, 1990, 34: 144-163. YELLOW FEVER IN RIO DE JANEIRO AND THE PASTEUR INSTITUTE MISSION (1901-1905): THE TRANSFER OF SCIENCE TO THE PERIPHERY by ILANA LOWY * Science, a purely European enterprise, began to be exported to peripheral countries in the nineteenth century. The rapid expansion ofbacteriology is a striking example of this. But at the same time, the transformation of bacteriology into a well-established and codified scientific discipline hampered the diffusion ofbacteriological knowledge, because the laboratory practice that developed in peripheral countries in the first wave of enthusiasm for the "miracle-making" science often failed to conform to the discipline's new, more stringent professional standards. The problem was ofparticular importance in bacteriology, in whose birth the techniques which allowed appropriate visualization, isolation, and characterization ofmicro-organisms played a crucial role. Indeed, debates on technical aspects of bacteriological investigation were at the heart of early controversies in this field. The story ofthe search for the agent ofyellow fever in Rio de Janeiro illustrates this evolution ofbacteriology. In the 1880s and 90s numerous enthusiastic Latin American adepts ofthe new science started to look for the aetiological agents oftropical diseases. In Brazil, a favourite target of bacteriological studies was yellow fever. However, the efforts of many bacteriologists notwithstanding, both the epidemiology of the disease and the nature of its aetiological agent remained for long mysterious. There were a dozen or so triumphant announcements of the isolation of the "yellow fever germ" in the 1880s and 90s. Many of them came from physicians working in Rio de Janeiro, a city which suffered from regular outbreaks.
    [Show full text]
  • Spread of Human Retrovirus Infections in Individuals at the Second and Third Decades of Life in São Paulo, Brazil
    Open Access Austin Journal of HIV/AIDS Research Rapid Communication Spread of Human Retrovirus Infections in Individuals at the Second and Third Decades of Life in São Paulo, Brazil Caterino-de-Araujo A* and Campos KR Centro de Imunologia, Instituto Adolfo Lutz, Abstract Coordenadoria de Controle de Doenças, Secretaria de The authors comment the spread of the human immunodeficiency virus 1 Estado da Saúde de São Paulo, São Paulo, SP, Brazil (HIV-1) and the human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and *Corresponding author: Adele Caterino-de- HTLV-2, here named HTLV) in the last years (from 2010 to 2016) in individuals Araujo, Instituto Adolfo Lutz, Centro de Imunologia, at the second and third decades of life in Brazil and in São Paulo city. Data on Coordenadoria de Controle de Doenças, Secretaria de the age and gender of 1,715 HIV-1-infected individuals whose blood samples Estado da Saúde de São Paulo, São Paulo, SP, Brazil were sent to Instituto Adolfo Lutz for HTLV-1/-2 infections determination were analyzed, and they were compared with the facts described in the Brazilian Received: December 12, 2017; Accepted: December 27, scientific literature. These retroviruses in adolescents and young adults is on 2017; Published: December 29, 2017 the increase, and the unprotected sexual contact has been presently pointed as the probable risk factor associated with these retroviruses spread in this parcel of population. These data are of concern, and the surveillance study on these viruses is justified for properly controlling the retroviruses spread in the country. Keywords: Human retroviruses; HIV-1; HTLV; Risk factors; Surveillance Abbreviations The study population was divided into five age-groups (G1: 16 to 25 years, G2: 26 to 30 years, G3: 31 to 40 years, G4: 41 to 50 years, and AIDS: Acquired Immune Deficiency Syndrome; ELISA: Enzyme G5: >50 years old), and according to the gender.
    [Show full text]
  • Spread” of Jungle Yellow Fever
    doi: 10.5216/rpt.v47i1.52274 OPINION ARTICLE THE ‘SPREAD” OF JUNGLE YELLOW FEVER Fernando Dias de Avila-Pires ABSTRACT The saga of yellow fever has been recounted by several science historians. It is a chronicle of errors, fight for recognition, historical mis-interpretations, and human experiments that would be unacceptable today. But it is also a record of forecasts that would be later confirmed by sound field work and through laboratory and clinical research. It is also an example of the contribution of local native lore to sound scientific discoveries. In this paper we try to demonstrate how we are advancing towards the natural foci of the jungle cycles of a zoonosis, not the reverse. KEY WORDS: Yellow fever; geographical distribution; epizootiology; epidemics. The saga of yellow fever has been recounted by several science historians and is now known in great detail. It is a chronicle of errors (Nogush, 1920), fight for recognition, historical mis-interpretations, and experiments that would be unacceptable today (Kelly, 1906; de Kruif, 1926; Delaporte, 1989). But it is also a record of forecasts that were to be confirmed by sound field work (Lutz, 1930) and laboratory and clinical research. It is also an example of the contribution of local lore to scientific discoveries (Balfour, 1914). The reader of this paper deserves to be spared tiresome repetitions. It is enough to recall that it arrived in Brazil, in the State of Pernambuco in the year of 1685, and in Rio de Janeiro, in 1894. A few references will be enough to introduce the subject of the present contribution to the knowledge of the jungle cycle of yellow fever in Brazil.
    [Show full text]
  • Downloads.Ibge.Gov.Br/Downloads Geociencias.Html
    Lorenz et al. Malar J (2015) 14:408 DOI 10.1186/s12936-015-0934-6 RESEARCH Open Access Spatial and temporal epidemiology of malaria in extra‑Amazonian regions of Brazil Camila Lorenz1,2*†, Flávia Virginio1,2†, Breno S. Aguiar4, Lincoln Suesdek1,2,3 and Francisco Chiaravalloti‑Neto4 Abstract Background: Mosquitoes, Plasmodium parasites, and humans live in sympatry in some extra-Amazonian regions of Brazil. Recent migrations of people from Amazonia and other countries to extra-Amazonian regions have led to many malaria outbreaks. Lack of relevant expertise among health professionals in non-endemic areas can lead to a neglect of the disease, which can be dangerous given its high fatality rate. Therefore, understanding the spatial and temporal epidemiology of malaria is essential for developing strategies for disease control and elimination. This study aimed to characterize imported (IMP) and autochthonous/introduced (AU/IN) cases in the extra-Amazonian regions and identify risk areas and groups. Methods: Epidemiological data collected between 2007 and 2014 were obtained from the Notifiable Diseases Information System of the Ministry of Health (SINAN) and from the Department of the Unified Health System (DATA‑ SUS). High malaria risk areas were determined using the Local Indicator of Spatial Association. IMP and AU/IN malaria incidence rates were corrected by Local Empirical Bayesian rates. Results: A total of 6092 malaria cases (IMP: 5416, 88.9 %; AU/IN: 676, 11.1 %) was recorded in the extra-Amazonian regions in 2007–2014. The highest numbers of IMP and AU/IN cases were registered in 2007 (n 862) and 2010 (n 149), respectively.
    [Show full text]
  • Tetravalent Dengue Vaccine
    Tetravalent Dengue Vaccine - Butantan Institute Developing Countries Vaccine Manufacturers Network Hanoi, Vietnam 7-9th, Ocotber, 2013 Dengue Epidemiology and Clinical Disease • Mosquito-borne flavivirus disease - tropical and subtropical areas • The incidence of dengue has increased 30-fold over the last 50 years • Up to 50-100 million infections annually in over 100 endemic countries Instituto Butantan | 1 Dengue Vaccine Development • Based on the complexity of dengue immunology and pathogenesis several challanges to vaccine development have been identified; • In spite of these challenges, vaccine development has made remarkable progress in recent years, and the current dengue vaccine pipeline is advanced, diverse and, in overall, promising; Instituto Butantan | 2 Instituto Butantan | 3 PROSPECTS FOR A DENGUE VACCINE • Goals of Immunization • First, the vaccine must be protective against each of the four DENV serotypes; • Second, the DENV vaccine should provide lifelong protection; • Third, immunization should be safe and well tolerated; • Fourth, universal coverage should be a goal in endemic regions; • Fifth, the cost of the vaccine must be affordable to the countries most in need of it. Instituto Butantan | 4 Dengue Vaccine Development at Butantan • The production of a live attnuated tetravalent dengue vaccine in Brazil is the result of a partnership between the Laboratory of Infectious Diseases at The National Institutes of Allergy and Infectious Diseases - NIH and Butantan Institute. Instituto Butantan | 5 A live attenuated dengue vaccine approach was chosen by NIH for several reasons: 1) First, live vaccines are expected to stimulate both cellular and humoral immune responses, therefore are able to induce a strong memory response and durable immune response; 2) Second, LA vaccines for other related flaviviruses such as yellow fever and Japanese encephalitis virus have been successfully developed; 3) Third, LA vaccines can be very economical to produce, helping to ensure that the countries most in need of a dengue vaccine will have access.
    [Show full text]
  • Hypervirulent Klebsiella Pneumoniae As Unexpected Cause of Fatal Outbreak in Captive Marmosets, Brazil Juliana Mariotti Guerra, Natália Coelho Couto De A
    Hypervirulent Klebsiella pneumoniae as Unexpected Cause of Fatal Outbreak in Captive Marmosets, Brazil Juliana Mariotti Guerra, Natália Coelho Couto de A. Fernandes, Alessandra Loureiro Morales dos Santos, Joana de Souza Pereira Barrel, Bruno Simões Sergio Petri, Liliane Milanelo, Monique Ribeiro Tiba-Casas, Alcina Maria Liserre, Cláudia Regina Gonçalves, Cláudio Tavares Sacchi, José Luiz Catão-Dias, Carlos Henrique Camargo. After the sudden death of captive marmosets in São signs, including anorexia, prostration, fever, cough, Paulo, Brazil, we conducted a histologic and microbio- dyspnea, mucopurulent discharge, meningitis, pneu- logic study. We found hyperacute septicemia caused monia, peritonitis, and sepsis are strongly associated by hypermucoviscous sequence type 86 K2 Klebsiella with sporadic infections of K. pneumoniae in common pneumoniae. We implemented prophylactic antimicrobial marmosets research colonies (5,6). therapy, selected dedicated staff for marmoset interac- Despite the well-recognized zoonotic importance tions, and sanitized the animals’ fruit to successfully con- of hvKp and the public health risk of emerging multi- trol this outbreak. drug-resistant strains (7–9), information is incomplete about the genotypic and phenotypic characterization lebsiella pneumoniae is an opportunistic bacteria of the etiologic agent essential to adequately diagnose that is a normal part of the nasopharyngeal and K and treat this pathogen in captive and wild nonhu- gastrointestinal tract microbiome of humans and ani- man primates. The aim of this study was to report an mals (1). The hypermucoviscous variant of K. pneu- epizootic among common marmosets in a wildlife moniae (hvKp), initially described in Southeast Asia, rehabilitation center in Brazil and to describe the se- has emerged as a pathogen affecting young and rotype, sequence typing, virulence properties, and re- healthy persons worldwide (2).
    [Show full text]