Editors •

Editor-in-Chief

JOSÉ MERINO, MD, MPHIL, FAAN Department of Neurology Georgetown University School of Medicine Washington, DC Specialties: Neurology, vascular neurology

Deputy Editor

OLGA CICCARELLI, MD, PhD, FRCP Dept. of Neuroinflammation UCL Institute of Neurology London, UNITED KINGDOM Specialties: Multiple sclerosis, neuroimaging, autoimmune diseases, clinical trials, outcome measures

Deputy Editor for Editorial Education and Associate Editor

BRADFORD B. WORRALL, MD, MSc, FAAN University of Virginia Dept. of Neurology Charlottesville, VA Specialties: Vascular neurology, genetics, ethical and methodological issues in translational research, epidemiology

1 Associate Editors • Neurology

PETER HEDERA, ANTHONY A. AMATO, REBECCA BURCH, MD, FAHS JOHN R. CORBOY, MD, FAAN JOSEP O. DALMAU, MD, PhD MD, PhD MD, FAAN Brigham and Women’s Hospital EDITOR, NEUROLOGY: EDITOR, NEUROLOGY: Vanderbilt University Brigham and Women’s Hospital Department of Neurology, CLINICAL PRACTICE NEUROIMMUNOLOGY & Dept. of Neurology Hale Building for Division of Headache and Pain NEUROINFLAMMATION University of Colorado Nashville, TN Transformative Medicine Boston, MA School of Medicine Catalan Institution of Research Boston, MA Specialties: Movement disorders, Specialties: Headache Medicine and Advanced Studies Dept. of Neurology neurogenetics, ataxia, essential Specialties: Neuromuscular, tremor, hereditary spastic EMG/NCV, diabetic neuropathy, Rocky Mountain Multiple (ICR EA) Hospital Clinic/IDIBAPS Sclerosis Center at CU Service of Neurology paraplegia, dystonia, Parkinson facial-scapulo-humoral dystrophy, disease, Huntington disease Lambert-Eaton syndrome, Aurora, CO Barcelona, SPAIN mitochondrial disorders, motor Specialties: Neurovirology, neuron disease, muscular Dept. of Neurology multiple sclerosis, neuroeducation, dystrophies, myasthenia gravis, Hospital of the University of diagnostics, therapeutics myopathies Pennsylvania Philadelphia, PA Specialties: Neuro-oncology and neuroimmunology

LINDA A. HERSHEY, BARBARA C. JOBST, MD, STEFAN M. PULST, MD, FAAN RENÉE SHELLHAAS, MD, MS MD, PhD, FAAN PhD, FAAN EDITOR, NEUROLOGY: Clinical Professor of Pediatrics University of Oklahoma Dartmouth-Hitchcock GENETICS Director of Research Epilepsy Center & Dept. of Michigan Medicine Pediatric Health Sciences Center. University of Utah Neurology Neurology Edmond, OK Dept. of Neurology Specialties: Dementia and Dartmouth-Hitchcock Salt Lake City, UT CS Mott Children’s Hospital Medical Center Ann Arbor, MI behavioral disorders, including Specialties: Genetics, movement Alzheimer disease, dementia Lebanon, NH disorders Specialties: Pediatric epilepsy, with Lewy bodies, mild cognitive Specialties: Epilepsy, epilepsy neonatal neurology impairment, vascular dementia, surgery, brain stimulation, self- progressive supranuclear palsy, management, cognition in epilepsy corticobasal degeneration, frontotemporal dementia, Huntington disease

2 Assistant Editors • Neurology

JONATHAN GRAFF-RADFORD, JENNIFER GRAVES, MD, MD PHD, MAS ASSISTANT EDITOR ASSISTANT EDITOR Mayo Clinic Associate Professor of Dept. of Neurology Neurosciences Rochester, MN Director of the UCSD Specialties: Mild cognitive Neuroimmunology Research impairment, Alzheimer disease, Program frontotemporal dementia, vascular cognitive impairment, dementia with Director Rady Children’s Lewy bodies Pediatric MS Center ACTRI La Jolla, CA Specialties: Multiple sclerosis, neuroimmunology, neuro- ophthalmology, epidemiology, genetics, digital health

3 Classification of Evidence and Biostatistics • Neurology

GARY S. GRONSETH, RICHARD J. KRYSCIO, PhD V. SHANE PANKRATZ, PhD SUE LEURGANS, PhD MD, FAAN ASSOCIATE EDITOR, BIOSTATISTICS BIOSTATISTICS ASSOCIATE EDITOR, BIOSTATISTICS Director, Biostatistics Shared Depts. of Neurological Sciences & CLASSIFICATION OF EVIDENCE University of Kentucky Resource Preventive Medicine EVALUATIONS Lexington, KY UNM Comprehensive Cancer Statistics, Rush Alzheimer’s University of Kansas Specialties: Clinical trials, ALS, Center Disease Center Medical Center Alzheimer disease, Parkinson disease, Kansas City, KS cancer, space-time Professor, Dept. of Internal Rush University Medical Center Medicine Chicago, IL Specialties: Biostatistics, clinical trials, epidemiology UNM Health Sciences Center Specialty: Biostatistics Albuquerque, NM Specialty: Biostatistics, longitudinal data analysis, clinical trials, causal analysis

4 Section Editors • Neurology

LEALANI MAE Y. ACOSTA, EDUARDO E. BENARROCH, GRETCHEN L. BIRBECK, BRIAN C. CALLAGHAN, STACEY L. CLARDY, MD, MD, MPH MD, FAAN MD, MPH, DTMH, FAAN MD, MS PhD, FAAN EDITOR, HUMANITIES IN EDITOR, BASIC SCIENCE IN EDITOR, WITHOUT BORDERS EDITOR, INNOVATIONS IN EDITOR, NEUROLOGY PODCAST NEUROLOGY THE CLINIC University of Rochester CARE DELIVERY University of Utah Vanderbilt University Medical Mayo Clinic Rochester, NY University of Michigan Imaging and Neuroscience Center Center Department of Rochester, MN Specialties: Tropical neurology, Dept. of Neurology Staff Neuroloist, VA Salt Lake Neurology Specialty: Autonomic epidemiology, health services Ann Arbor, MI City Health Care System Nashville, TN research Specialties: Neuromuscular, health Salt Lake City, UT Specialty: Cognitive services research, epidemiology Specialty: Autoimmune neurology, behavioral neurology neuroimmunology

STEVEN GALETTA, MD, FAAN ARAVIND GANESH, MD, DAVID S. KNOPMAN, LUDWIG GUTMANN, MD, ROY H. HAMILTON, MD, MD, FAAN EDITOR, DISPUTES & DEBATES DPHIL (OXON) FAAN MS, FAAN DEPUTY EDITOR, DISPUTES & SCIENTIFIC INTEGRITY SENIOR CONSULTING EDITOR, ASSOCIATE EDITOR, EQUITY, NYU School of Medicine DEBATES ADVISOR HUMANITIES IN NEUROLOGY DIVERSITY, AND INCLUSION Dept. of Neurology SECTION NY, NY Department of Clinical Mayo Clinic Department of Neurology Neurosciences Dept. of Neurology University of Iowa Hospitals University of Pennsylvania Specialties: Neuro-ophthalmology, University of Calgary Rochester, MN and Clinics Philadelphia, PA idiopathic intracranial hypertension, multiple sclerosis, nystagmus, Calgary, CANADA Specialties: Behavioral neurology/ Iowa City, IA Specialties: Cognitive and ocular motility, optic nerve, optic neuropsychology, cognitive Neuromuscular Medicine behavioral neurology neuritis, visual fields, visual loss Specialities: Vascular and cognitive disorders, clinical trials, Clinical Neurophysiology neurology epidemiology, neuropsychology, Alzheimer disease, dementia with Professor of Neurology Lewy bodies, executive function, University of Iowa frontotemporal dementia, vascular Specialties: Neuromuscular dementia diseases, EMG/NCS, myopathies, neuropathies, ALS, neuromuscular junction disorders

5 Section Editors • Neurology

HOLLY E. HINSON, MD, MCR, JONATHAN P. HOSEY, MD, STEVEN KARCESKI, MD ADAM G. KELLY, MD, FAAN KEVIN A. KERBER, MD, MS FAAN FAAN EDITOR, PATIENT PAGE EDITOR, CONTINUING MEDICAL EDITOR, INNOVATIONS IN CARE ASSOCIATE EDITOR, EQUITY, EDITOR, SUPPLEMENTS Cornell Comprehensive EDUCATION DELIVERY DIVERSITY, AND INCLUSION St. Luke’s Neurology Associates Epilepsy Center Dept. of Neurology Dept. of Neurology SECTION Fountain Hill, PA Weill Cornell Medical College University of Florida College University of Michigan Associate Director of Clinical Specialties: Vascular neurology New York, NY of Medicine Health System Research, Neurocritical Care Gainesville, FL Ann Arbor, MI Program Specialties: Epilepsy, EEG, diagnostics Specialties: Cerebrovascular Specialties: Health services research, Associate Professor, Neurology diseases, medical decision making, neuro-otology and Emergency Medicine medical education Oregon Health & Science University Portland, OR Specialty: Neurocritical care

ARIANE LEWIS, MD JEFFREY C. MCCLEAN II, MD, NICTE I. MEJIA, MD, MPH, JOHN J. MILLICHAP, MD, JONATHAN W. MINK, DEPUTY EDITOR, DISPUTES & FAAN FAAN FAAN MD, PhD, FAAN DEBATES EDITOR, EQUITY, DIVERSITY, EDITOR, EQUITY, DIVERSITY, EDITOR, RESIDENT OMBUDSMAN NYU Langone Medical Center AND INCLUSION (EDI) AND INCLUSION (EDI) & FELLOW SECTION University of Rochester New York, NY Assistant Professor of Massachusetts General Epilepsy Center, Ann & Robert Dept. of Neurology Specialty: Neurocritical care Neurology, Uniformed Services Hospital H. Lurie Children’s Hospital Rochester, NY University of the Health Boston, MA of Chicago Specialties: Child neurology and Sciences Neurology Program Depts. of Pediatrics and movement disorders Director, San Antonio Uniformed Specialties: Movement disorders Neurology Services Health Education Northwestern University Consortium Feinberg School of Medicine Chicago, IL Chief of the Medical Staff, 959th Medical Group, Brooke Specialties: Pediatric epilepsy, Army Medical Center pediatric EEG, infantile seizures, febrile seizures, post-infectious/inflammatory Houston, TX epilepsy, epilepsy surgery Specialty: Neuromuscular medicine

6 Section Editors • Neurology

HEIDI GEORGE MOAWAD, MD JAMES W.M. OWENS, JR., JEFFREY B. RATLIFF, MD NICOLE ROSENDALE, MD JAMES E. SIEGLER III, MD EDITOR, HUMANITIES IN MD, PhD DEPUTY EDITOR, PODCASTS EDITOR, EQUITY, DIVERSITY, DEPUTY EDITOR, DISPUTES & NEUROLOGY EDITOR, CONTINUING MEDICAL Thomas Jefferson University AND INCLUSION (EDI) DEBATES Case Western Reserve University EDUCATION Dept. of Neurology ZSFG Neurology Hospital of University of School of Medicine University of Washington Philadelphia, PA San Francisco, CA Pennsylvania Dept. of Neurology Philadelphia, PA Clinical Assistant Professor, Specialties: Movement disorders, Specialty: Neurohospitalist Seattle Children’s Hospital Division of Medical Education medical education Specialty: Vascular neurology Seattle, WA John Carroll University Specialties: Pediatric neurology, Brecksville, OH epilepsy, sleep medicine, Specialties: Patient education, medical education medical communication, medical education, payment policy, professional development, neurodiversity

DAVID C. SPENCER, MD ROY E. STROWD III, MD EDITOR, PATIENT PAGE DEPUTY EDITOR, RESIDENT & Oregon Health & Science FELLOW SECTION University Wake Forest School of Medicine Dept. of Neurology Dept. of Neurology Portland, OR Dept. of Internal Medicine, Specialty: Epilepsy Section on Hematology & Oncology Winston Salem, NC Specialties: Neuro-oncology, primary brain tumors, leptomeningeal metastases, neurofibromatoses, medical education

7 Editorial Board • Neurology

ROGER L. ALBIN, MD CORRADO ANGELINI, CARMEL ARMON, OLIVER BANDMANN, BRENDA BANWELL, MD, University of Michigan MD, FMAA, FAAN MD, MSC, MHS, FAAN MD, PhD, FAAN FRCPC, FAAN Dept. of Neurology Dept. of Neurosciences Assaf Harofeh Medical Center Sheffield Institute of The Children’s Hospital of Ann Arbor, MI University of Padova Translational Neuroscience Philadelphia Tel Aviv University Sackler Padova, ITALY University of Sheffield Specialties: Movement disorders, Faculty of Medicine Perelman School of Medicine Sheffield,UNITED KINGDOM imaging, neuroanatomy, IRCCS Fondazione Dept. of Neurology University of Pennsylvania neurochemistry, neuropharmacology, San Camillo Hospital Tel Aviv, ISRAEL Specialties: Movement disorders, Philadelphia, PA essential tremor, Huntington Venice, ITALY genetics, genomics, dystonia, disease, Parkinson disease, tics, Academic Specialties: ALS, Huntington disease, Parkinson Specialties: Pediatric onset trinucleotide repeat diseases Specialties: Neuromuscular neuroepidemiology, clinical trials, disease, Tourette syndrome, , pediatric disorders, neurogenetics, evidence-based medicine pathogenesis multiple sclerosis neuropediatrics, metabolic disorders Practice Specialties: ALS, EMG, inpatient neurology (including stroke, epilepsy, status epilepticus)

SERGIO BARANZINI, PhD FREDERIK BARKHOF, MD, PhD DAVID A. BENNETT, MD ANNE T. BERG, PhD ANDREA BERNASCONI, MD University of California, Institutes of Neurology and Rush Alzheimer’s Disease Center Ann & Robert H. Lurie Children’s Montreal Neurological Institute San Francisco Biomedical Engineering, UCL, Hospital of Chicago Montreal, Quebec Robert C. Borwell Professor Dept. of Neurology London of Neurological Sciences Northwestern University Subspecialty: Epilepsy, imaging of San Francisco, CA Dept. of Radiology & Nuclear Feinberg School of Medicine epilepsy Rush University Medical Center Specialties: Multiple sclerosis, Medicine Chicago, IL genomics, systems biology, Chicago, IL Specialties: Epidemiology, epilepsy bioinformatics, immunology Neuroscience Campus Specialties: Geriatric neurology, Amsterdam neurodegenerative disease, VU University Medical Hospital epidemiology, Alzheimer disease, Amsterdam, dementia with Lewy bodies, gait disorders, intelligence, THE NETHERLANDS natural history, pathogenesis Specialties: Neuroradiology, MRI, multiple sclerosis, dementia

8 Editorial Board • Neurology

FRANK BIRKLEIN, MD, PhD DENNIS BOURDETTE, AMY BRODTMANN, DEVIN L. BROWN, MD, MS JOHN C.M. BRUST, MD, FAAN University Medical Centre MD, FAAN MD, PhD, FRACP University of Michigan Columbia University Mainz Dept. of Neurology Oregon Health & Science The Florey Institute for Stroke Program Medical Center Mainz, GERMANY University Neuroscience and Mental Health The Cardiovascular Center New York Neurological Institute Dept. of Neurology Melbourne Dementia Research Ann Arbor, MI Specialties: Pain, autonomic New York, NY diseases, complex regional pain Portland, OR Centre Specialty: Stroke syndromes, neuropathic pain, Specialties: General neurology, Specialties: Multiple sclerosis, Austin Health, Eastern Health headache, movement disorders, peripheral nerve trauma, peripheral neuroimmunologic diseases, and Melbourne Health neuropathy, pathophysiology aphasia, apraxia, stroke, nutritional demyelinating disease Melbourne Brain Centre disorders, alcohol and substance Melbourne, AUSTRALIA abuse, coma, metabolic disorders, CNS infection, AIDS Specialties: Stroke, dementia, vascular cognitive impairment, cognitive neurology, frontotemporal dementia

BRUCE C.V. CAMPBELL, PhD FERNANDO CENDES, MD, PhD COLIN H. CHALK, SEEMANT CHATURVEDI, MD, ROBERT CHEN, MA, MDCM, FRCPC FAAN, FAHA MBBCHIR, MSc, FRCPC Royal Melbourne Hospital University of Campinas–UNICAMP Dept. of Neurology Dept. of Neurology Dept. of Neurology & Greenebaum Endowed University of Toronto Campinas, SP, BRAZIL Neurosurgery Professor of Neurology Parkville VIC, AUSTRALIA Toronto Western Hospital Specialties: Stroke and stroke Specialties: Imaging, functional McGill University, Room L7-313 University of Maryland School Toronto, Ontario, CANADA imaging, anatomic imaging, imaging Montreal General Hospital of Medicine Specialties: Movement disorders, epilepsy, EEG, partial seizures, Montreal, Quebec, CANADA Baltimore, MD epilepsy surgery neurophysiology, motor control, Specialties: Peripheral neuropathy, Specialties: Vascular neurology, transcranial magnetic stimulation, myasthenia gravis, medical stroke, carotid stenosis, intracranial deep brain stimulation education atherosclerosis, strong in young adults

9 Editorial Board • Neurology

KELVIN L. CHOU, MD, FAAN MARINOS C. DALAKAS, LISA M. DEANGELIS, ROBERT J. FOX, MD, FAAN ANSGAR J. FURST, MSc, PhD Professor, Neurology and MD, FAAN MD, FAAN Mellen Center for Stanford University Neurosurgery Professor of Neurology Dept. of Neurology Multiple Sclerosis School of Medicine (endowed Chair) Memorial Sloan-Kettering Cleveland Clinic Depts. of Neurology & Associate Chair of Faculty Cancer Center Cleveland, OH Neurological Sciences and Development & Finance, Director, Neuromuscular New York, NY Psychiatry & Behavioral Neurology Division Specialties: Multiple sclerosis Specialties: Neuro-oncology, cancer, and neuroimaging Sciences Michigan House Thomas Jefferson University gliomas, metastatic tumor, nerve Stanford, CA Ann Arbor, MI Philadelphia, PA tumors, paraneoplastic syndrome, US Dept. of Veterans Affairs, Specialties: Neuromuscular pediatric brain tumors, primary brain Palo Alto, CA disorders, autoimmune neurology, tumor, radiation necrosis, spinal immunotherapies cord tumor Specialties: Neuroimaging of traumatic brain injury and Alzheimer disease

STEVEN GALETTA, MD, FAAN JEROEN J.G. GEURTS, PhD M. MARIA GLYMOUR, PETER J. GOADSBY, MD, DSc LARRY B. GOLDSTEIN, NYU School of Medicine VU University Medical Center ScD, MS University of California MD, FAAN Dept. of Neurology Amsterdam, Dept. of Epidemiology and San Francisco Kentucky Neuroscience Institute New York, NY THE NETHERLANDS University of Kentucky Biostatistics Headache Center Lexington, KY Specialties: Neuro-ophthalmology, Specialties: Multiple sclerosis, University of California Dept. of Neurology idiopathic intracranial hypertension, cognition, grey matter atrophy, San Francisco Specialties: Stroke, TIA, multiple sclerosis, nystagmus, cognitive rehabilitation San Francisco, CA University of California cardiovascular/stroke, clinical trials, ocular motility, optic nerve, optic San Francisco epidemiology, arterial dissection, neuritis, visual fields, visual loss Specialty: Epidemiology San Francisco, CA cerebral venous thrombosis, embolism, stroke in young adults, Specialty: Headache subarachnoid hemorrhage

10 Editorial Board • Neurology

NICOLE R. GONZALES, MD CLIFTON L. GOOCH, RENZO GUERRINI, MD, FRCP AMANDA C. GUIDON, MD OSKAR HANSSON, MD, PhD University of Texas MD, FAAN Children’s Hospital A. Meyer Department of Neurology, Clinical Memory Research Unit, University of South Florida Division of Neuromuscular Lund University, Sweden UT Health Science Center University of Florence Tampa, FL Medicine Houston, TX Neuroscience Dept. Memory Clinic, Skåne University Specialties: Neuromuscular, Florence, ITALY Director, MGH Myasthenia Hospital Specialty: Vascular neurology EMG/NCV, clinical trials, carpal Gravis Clinic Malmö, SWEDEN tunnel syndrome, chronic Specialties: Pediatric inflammatory demyelinating epilepsy, genetics of epilepsy, Program Director, Partners Specialties: Dementia, , diabetic neuropathy, neurophysiology of epilepsy, Neuromuscular Medicine neurocognitive disorders, Lambert-Eaton syndrome, motor myoclonus, brain malformations, Fellowship dementia biomarkers and imaging neuron disease, myasthenia gravis, genetic malformations of cortical peripheral nerve trauma, peripheral development Massachusetts General Hospital neuropathy, multifocal motor Boston, MA neuropathy, chemotherapy-induced Specialties: Neuromuscular and peripheral neuropathy electrodiagnostic medicine, myasthenia gravis, neurologic complications of cancer immunotherapy

NOAM Y. HAREL, MD, PhD JUDITH U. HARRER, MD ADAM HARTMAN, MD, FAAN GEOFFREY L. HEYER, MD REINHARD HOHLFELD, MD Neurology and Rehabilitation Neurologische Privatpraxis in National Institute of Dept. of Neurology Institute for Clinical Medicine der Villa Pfahler Neurological Disorders Dell Medical School Neuroimmunology Icahn School of Medicine at Ingbert, GERMANY & Stroke Austin, Texas Klinikum der LMU München Neuroscience Center München, GERMANY Mount Sinai Dept. of Neurology Specialty: Pediatric neurology Rockville, MD Specialties: Immunopathogenesis Investigator, Spinal Cord RWTH Aachen University Hospital Aachen, GERMANY Subspecialties: Pediatric neurology, and treatment of neuro- Damage Research Center epilepsy, ketogenic diet immunological disorders Specialties: Cardiovascular/stroke, James J. Peters VA Medical stroke in the young, neuroimaging, Center perfusion imaging, and transcranial Bronx, NY ultrasound Specialties: Neurorehabilitation, spinal disorders

11 Editorial Board • Neurology

REBECCA ICHORD, MD NATHALIE JETTÉ, MD, GLEN C. JICKLING, MD, LARRY JUNCK, MD LALIT KALRA, FRCP, PhD Perelman School of Medicine MSC, FRCPC MAS, FRCPC University of Michigan Dept. of Stroke Medicine University of Pennsylvania Icahn School of Medicine at University of California Davis Dept. of Neurology and Rogel Academic Neurosciences Mount Sinai Dept. of Neurology Cancer Center Centre PO41 Dept. of Neurology Dept. of Neurology Sacramento, CA Ann Arbor, MI Children’s Hospital of Philadelphia Institute of Psychiatry New York, NY Philadelphia, PA Specialties: Vascular neurology and Specialties: Neuro-oncology, King’s College London Specialties: Epilepsy, epidemiology, gene expression gliomas, brain metastases, CNS Specialties: Child neurology, London, UNITED KINGDOM health services research lymphomas, brain radiation injury, child stroke neurosarcoidosis, bioethics, Specialty: Stroke medicine neurological consequences of climate change

PETER B. KANG, MD, FAAN MIRA KATAN, MD, MS JOEP KILLESTEIN, MD, PhD CHRISTOPHER J. KLEIN, MD DAVID S. KNOPMAN, MD, FAAN University of Florida College Dept. of Neurology Amsterdam University Mayo Clinic of Medicine Division of Stroke Medical Center Peripheral Neuropathy Mayo Clinic Division of Pediatric Neurology University Hospital Zurich Dept. of Neurology, Research Laboratory Dept. of Neurology Gainesville, FL Zürich, SWITZERLAND MS Center Amsterdam Rochester, MN Rochester, MN Amsterdam, Subspecialties: Pediatric neurology, Subspecialties: Blood biomarkers Subspecialties: Genetics, genetics, neuromuscular disorders in the field of stroke and migraine, THE NETHERLANDS neuropathy Specialties: Behavioral neurology/ blood biomarker discovery using Specialities: Multiple sclerosis, neuropsychology, cognitive OMICs methods, biomarker progressive multifocal disorders, clinical trials, implementation in clinical care, leukoencephalopathy, epidemiology, neuropsychology, acute treatment of stroke, stroke neuroimmunology, Alzheimer disease, dementia with outcome research body fluid biomarkers Lewy bodies, executive function, frontotemporal dementia, vascular dementia

12 Editorial Board • Neurology

SUSAN M. LANDAU, PhD MARK S. LEDOUX, RICHARD J. LEVENTER, RICHARD B. LIPTON, ALBERTO LLEÓ, MD, PhD MD, PhD, FAAN Helen Wills Neuroscience MBBS, BMedSci, FRACP, PhD MD, FAAN Neurology Dept. Institute University of Tennessee Dept. of Neurology Dept. of Neurology Hospital de la Santa Creu i Health Science Center Royal Children’s Hospital Albert Einstein College University of California, Sant Pau Dept. of Neurology Melbourne, AUSTRALIA of Medicine Berkeley Barcelona, SPAIN Memphis, TN Berkeley, CA Specialties: Brain development, Bronx, NY 10461 Specialties: Cognitive disorders, Subspecialties: General neurology, brain malformations, neurogenetics, Specialties: Neuroimaging in Specialties: Headache, health dementia Alzheimer disease and aging movement disorders, neurogenetics pediatric neurology services, neurodegenerative disease, clinical trials, epidemiology, Alzheimer disease, migraine, tension headache

WARREN D. LO, MD SVETLANA LORENZANO, KENNETH J. MACK, JENNIFER JUHL MAJERSIK, ANDREW L. MAMMEN, MD, Nationwide Children’s Hospital MD, PhD, MSC MD, PhD, FAAN MD, MS, FAAN, FAHA PhD Columbus, OH Dept. of Neurology and Mayo Clinic University of Utah Muscle Disease Unit Specialties: Child neurology; Psychiatry Dept. of Neurology/Child Department of Neurology Laboratory of Muscle Stem Cells pediatric stroke, infant rehabilitation Policlinico Umberto and Adolescent Salt Lake City, UT and Gene Regulation Hospital Sapienza University Rochester, MN Specialties: Vascular neurology, National Institute of of Rome Specialties: Chronic daily headache, clinical trials, epidemiology, Musculoskeletal and Skin Rome, ITALY chronic migraine, transformed cost-effectiveness analyses Diseases migraine, headache, pediatric Specialties: Stroke/vascular National Institutes of Health neurology, cerebrovascular diseases, neurology, genetics, migraine, acute stroke, acute ischemic tics, Tourette syndrome Bethesda, MD stroke, intracerebral hemorrhage, Specialty: Neuromuscular medicine thrombolysis, imaging, molecular biomarkers, translational research, clinical trials

13 Editorial Board • Neurology

RANDOLPH S. MARSHALL, KIMFORD J. MEADOR, JOHN W. MILLER, MD, NILS MUHLERT, PhD PHILLIP L. PEARL, MD, FAAN MD, MS, FAAN MD, FAAN, FRCPE PhD, FAAN University of Manchester Boston Children’s Hospital Dept. of Neurology Dept. of Neurology & University of Washington School of Psychological Harvard Medical School Columbia Presbyterian Neurological Sciences UW Regional Epilepsy Center Sciences Boston, MA Medical Center Stanford Neuroscience Dept. of Neurology Manchester, UNITED KINGDOM Specialties: Child neurology, New York, NY Health Center Seattle, WA Subspecialties: Multiple sclerosis, epilepsy, pediatric epilepsy Specialties: Neurology, vascular Stanford University School Specialties: Clinical epilepsy, clinical cognition, neuropsychology, MRI neurometabolism/metabolic neurology of Medicine neurophysiology, epilepsy surgery, diseases, neurotransmitter diseases, neurogenetics Palo Alto, CA experimental models of epilepsy Specialties: Behavioral neurology, neuropsychology, epilepsy, epilepsy surgery, epilepsy and pregnancy, neuropharmacology of cognition, neurophysiology of cognition, clinical neurophysiology, clinical trials, attention, consciousness, neglect syndrome

TONI S. PEARSON, MD JOEL S. PERLMUTTER, KATHRYN M. REXRODE, MARIA A. ROCCA, MD INGRID E. SCHEFFER, Dept. of Neurology MD, FAAN MD, MPH Neuroimaging Research Unit, AO, MBBS, PhD, FRACP Washington University School Washington University Chief, Division of Women’s Health Institute of Experimental Florey Institute of Medicine School of Medicine Neurology, Division of Dept. of Medicine, Brigham and University of Melbourne St. Louis, MO Dept. of Neurology Neuroscience, San Raffaele Women’s Hospital Specialities: Child neurology, St. Louis, MO Scientific Institute, Vita-Salute Austin Health and Royal Associate Professor of Medicine, Children’s Hospital pediatric movement disorders Specialties: Movement disorders, San Raffaele University imaging, functional imaging, Harvard Medical School Milan, ITALY Melbourne, AUSTRALIA chorea, dystonia, Parkinson disease, Subspecialties: Stroke, Specialties: Multiple sclerosis, Specialties: Epilepsy, pediatric progressive supranuclear palsy epidemiology, women’s health, headache, NMOSD, neuroimaging, epilepsy, genetics, epilepsy sex differences cognition, clinical trials classification, clinical research, women in science

14 Editorial Board • Neurology

DAVID SCHIFF, MD, FAAN KEVIN N. SHETH, MD, FAAN HITOSHI SHINOTOH, MD, PhD ERIC EDWARD SMITH, MD, LUCIANO A. SPOSATO, Neuro-Oncology Center Yale School of Medicine & Neurology Clinic Chiba MPH, FRCPC MD, MBA Yale New Haven Hospital Chiba, JAPAN Calgary, AB, CANADA Dept. of Clinical Neurological Depts. of Neurology, New Haven, CT Sciences Neurological Surgery, Subspecialties: Movement Specialties: Stroke, dementia and Medicine Subspecialties: Vascular neurology disorders, dementia, PET University Hospital (stroke) and neuroscience London Health Sciences Centre University of Virginia critical care Charlottesville, VA The Western Ontario University Specialties: Neuro-oncology, London, ON, CANADA gliomas, primary brain lymphoma, Subspecialties: Epidemiology, brain metastasis, spinal cord tumors, cardioembolic stroke, atrial and neurological complications of fibrillation cancer therapy

MICHAEL STRUPP, MD, LIU LIN THIO, MD, PhD EDWIN TREVATHAN, MD, JACK W. TSAO, MD, Dphil, KENNETH L. TYLER, MD, FAAN FRCP Washington University MPH, FAAN FAAN University of Colorado School Dept. of Neurology School of Medicine Amos Christie Chair in Global Dept. of Neurology of Medicine and German Center for Vertigo Dept. of Neurology Health University of Tennessee Health Aurora, CO 80045 and Balance Disorders St. Louis, MO Professor of Pediatrics and Science Center Specialties: CNS infection, Neurology Ludwig Maximilians University, Subspecialties: Pediatric neurology, Neurology Service neurovirology, history of neurology Munich pediatric epilepsy, epilepsy surgery, Director, Vanderbilt Institute for Memphis Veterans Affairs Munich, GERMANY EEG, ketogenic diet, cellular Global Health Medical Center neurophysiology Memphis, TN Specialties: Vertigo, dizziness, Vanderbilt University Medical balance disorders, gait disorders, Center Specialties: Concussion, phantom limb neuro-otology, neuro-ophthalmology, pain, chemodenervation, dementia nystagmus, downbeat nystagmus, Nashville, TN cerebellar ataxia, pharmacotherapy, Subspecialties: General child post-lumbar puncture headache neurology, epilepsy, epidemiology/ neuroepidemiology, global health/ public health, health policy; maternal- child health

15 Editorial Board • Neurology

ANGELA VINCENT, FRCPath FRANCOIS J.G. KATJA E. WARTENBERG, NICOLE I. WOLF, MD, PHD E. ANN YEH, MD FMedSci FRS VINGERHOETS, MD MD, PhD Amsterdam University University of Toronto Nuffield Dept. of Clinical Service de Neurologie (BH13) Neurocritical Care and Medical Centers Hospital for Sick Children Neurosciences Stroke Unit Dept of Child Neurology Division of Neurology. CHUV Level 5/6 West Wing Dept. of Neurology Amsterdam, Toronto, ON CANADA Lausanne, SWITZERLAND John Radcliffe Hospital THE NETHERLANDS University of Leipzig Specialties: Child neurology, Specialty: Movement disorders demyelination, inflammatory brain Oxford, UNITED KINGDOM Specialties: Child neurology, Leipzig, GERMANY disease, multiple sclerosis, ADEM, leukodystrophies, neurogenetics, Specialties: Antibody-mediated optic neuritis, transverse myelitis neurological disorders Specialty: Neurocritical care neurometabolic disorders, MRI

16 Classification of Evidence Review Team • Neurology

GARY S. GRONSETH, MD MELISSA J. ARMSTRONG, RICHARD BARBANO, MD, RICHARD M. DUBINSKY, JEFFREY J. FLETCHER, SECTION EDITOR MD, MSc, FAAN PhD, FAAN MD, MPH, FAAN MD, MSc Dept. of Neurology University of Rochester University of Kansas Bronson Methodist Hospital University of Kansas University of Florida Professor of Neurology Dept. of Neurology Kalamazoo, MI Medical Center Gainesville, FL Chief, Movement Disorders Div. Kansas City, KS Kansas City, KS Specialties: Vascular neurology, Specialties: Movement disorders, Specialties: Movement disorders, neurocritical care Specialties: Biostatistics, Associate Chair of Community evidence-based guidelines, patient neuroepidemiology, evidence-based clinical trials, epidemiology Outreach and Regional Dev. engagement medicine, clinical trials Rochester, NY Specialties: Botulinum toxins, dystonia, movement disorders

GARY M. FRANKLIN, DAVID S. GLOSS, MD, JOHN J. HALPERIN, MD, FAAN JASON LAZAROU, MD, FRCPC STEVEN R. MESSÉ, MD, FAAN MD, MPH, FAAN MPH, TM Overlook Medical Center Mount Sinai Hospital Division of Stroke and University of Washington Charleston Area Medical Center Dept. of Neurosciences Toronto, ON, CANADA Neurocritical Care Seattle, WA Neurology Summit, NJ 07902 Specialties: General neurology, Hospital of the University Specialties: Neuroepidemiology Charleston, WV Specialties: Neuroinfectious EMG and NCS, EEG of Pennsylvania and health services research Specialties: Epilepsy, biostatistics, diseases, neuroimmunology, Dept. of Neurology clinical neurophysiology neuromuscular disease, Philadelphia, PA evidence-based medicine Specialty: Vascular neurology

PUSHPA NARAYANASWAMI, MBBS, DM, FAAN ALEX RAE-GRANT, MD, FRCP(C), FAAN Harvard Medical School/Beth Israel Deaconess Neurological Institute Cleveland Clinic Medical Center Mellen Center for Multiple Sclerosis Dept. of Neurology Cleveland, Ohio Boston, MA Specialty: Multiple sclerosis Specialties: Neuromuscular disorders and health services

17 Editors • Neurology: Clinical Practice

Editor Associate Editors

JOHN R. CORBOY, MD, FAAN DAVID C. ANDERSON, MD, FAAN RICHARD BARBANO, MD, PhD, FAAN LUCA BARTOLINI, MD University of Colorado University of Minnesota University of Rochester EDITOR, PRACTICE CURRENT Rochester, NY School of Medicine Saint Paul, MN Clinical Epilepsy Section and Division of Dept. of Neurology & Co-director Specialties: General neurology, stroke, and Specialties: Botulinum toxins, dystonia, Neuroimmunology and Neurovirology Rocky Mountain Multiple Sclerosis medical education movement disorders National Institute of Neurological Center at CU Disorders and Stroke Aurora, CO The Warren Alpert Medical School of Specialties: Neurovirology, multiple sclerosis, Brown University neuroeducation, diagnostics, therapeutics Director, Pediatric Epilepsy Program Providence, RI Specialties: Epilepsy, child neurology, and neuroinflammation

ARAVIND GANESH, MD, DPHIL (OXON) GARY R. CUTTER, PhD HAITHAM M. HUSSEIN, MD, MSC DEPUTY EDITOR, PRACTICE CURRENT CONTRIBUTING EDITOR CONTRIBUTING EDITOR Department of Clinical Neurosciences University of Alabama at Birmingham Medical Director Calgary, CANADA School of Public Health Regions Hospital Comprehensive Stroke Specialities: Vascular and cognitive neurology Dept. of Biostatistics Center Birmingham, AL HealthPartners Neurosciences Specialties: Clinical trials, epidemiologic St. Paul, MN studies, and evaluation research Specialties: Behavioral neurology/ neuropsychology, ethics, general neurology, stroke/vascular neurology, clinical trials, imaging, arterial dissection, cerebral venous thrombosis, infarction, intracerebral hemorrhage, subarachnoid hemorrhage, vasculitis, diagnostics, therapeutics

1 Editorial Board • Neurology: Clinical Practice

JAMES L. BERNAT, MD, FAAN JOSÉ BILLER, FACP, FAAN MURRAY FLASTER, MD, PhD LYELL K. JONES, JR., MD, BARBARA S. KOPPEL, FAAN Geisel School of Medicine at Loyola University Chicago Lancaster General Hospital MD, FAAN Dartmouth and Dartmouth- Dept. of Neurology Lancaster, PA Dept. of Neurology Dept. of Neurology Hitchcock Medical Center Maywood, IL Mayo Clinic, Rochester, MN Specialties: Vascular neurology, New York Medical College Hanover, NH Rochester, MN Specialties: Ischemic and neurointensive critical care, stroke, New York, NY Specialties: Bioethics, professional hemorrhagic cerebrovascular transient ischemic attack (TIA), Specialties: Neuromuscular, Specialties: AIDS and CNS conduct and misconduct, coma diseases (children, adults), carotid general neurology EMG/NCS, neurology education, infections, epilepsy, illicit and disorders of consciousness, artery disease, transient ischemic health policy, healthcare economics substance use, cocaine, alcohol brain death medicine, neurology attacks, CNS vascular malformations, and other neurotoxins, neurologic education clinical trials in stroke, neurology of systemic diseases, acute care complications of vitamin neurology/neurohospitalist medicine, deficiencies headache medicine

HEIDI MOAWAD, MD JOHN P. NEY, MD, MPH MARC R. NUWER, MD, TAMARA PRINGSHEIM, AMY A. PRUITT, MD, FAAN Case Western Reserve Acute and Specialty Care PhD, FACP, FAAN MD, MSc University of Pennsylvania University Service Line University of California Mathison Centre for Mental Philadelphia, PA Cleveland, OH Edith Nourse Rogers Los Angeles Health Research and Education Specialties: Neuro-oncology, Specialties: Patient education, VA Medical Center Dept. of Neurology Calgary, AB, CANADA complications of solid organ and Bedford, MA patient care, education, CAM, Reed Neurological Subspecialties: Movement hematopoietic cell transplantation, payment policy, healthcare policy, Specialties: Areas-cost of care, disorders, neuropsychiatry/ neuro-infectious diseases, Research Center neurological complications of professional development burden of illness, budget-impact, Los Angeles, CA neurology and mental health, cost-effectiveness, comparative headache medical illnesses effectiveness, health technology Specialties: CPT coding, evaluation assessment, health economics, and management services, health policy, health outcomes intraoperative monitoring, ICU EEG research, health services research, monitoring, epilepsy monitoring, evidence review, meta-analytic epilepsy patient care, EEG, evoked techniques, clinical neurophysiology, potentials, health care public policy, intraoperative neurophysiological health care reform monitoring, pain, neuromuscular, EEG, EMG, neurological procedures including botulinum toxin therapies

2 Editorial Board • Neurology: Clinical Practice

TERRY ROLAN, MD SATY SATYA-MURTI, ANURADHA SINGH, MD JACK W. TSAO, MD, TISSA WIJERATNE, Harry S. Truman Memorial MD, FAAN Chief of Neurology, DPhil, FAAN MD, FRACP, FAAN Veterans’ Hospital Health Policy Consultant Bellevue Hospital Center Memphis Veterans Affairs Neurology University of Columbia, MO Santa Maria, CA New York, NY Medical Center and Rajarata, Sri Lanka University of Tennessee Specialties: Movement disorders, Specialties: Coverage and related Specialties: Epilepsy, epilepsy University of Melbourne Health Science Center traumatic brain injury, evidence assessment, insurance seizure disorders, EEG, neuro- Stroke Unit and Research Unit neurotoxicology, sports neurology, coverage for new or emerging oncology, neuroradiology, Memphis, TN Dept. of Neurology Western neurology, and medicine in technologies, intersections neuromuscular disorders, general Subspecialties: Concussion, austere environments (interdisciplinary) of neurology with neurology, genetic disorders traumatic brain injury, Hospital other health care specialties, health chemodenervation, Melbourne, AUSTRALIA policy with emphasis on Medicare, phantom limb pain cognitive bias in clinical and Specialties: Advocacy, global forensic sciences issues in clinical practice, neurology education, stroke in the developing world, TIA, movement disorders, pain, stroke/vascular neurology, clinical trials, education, epidemiology, Parkinson disease, stroke in young adults

3 Editors • Neurology: Neuroimmunology & Neuroinflammation

Editor Deputy Editor

JOSEP O. DALMAU, MD, PhD SCOTT S. ZAMVIL, MD, PhD, FAAN Catalan Institution of Research and Advanced Dept. of Neurology and Program in Immunology Studies (ICREA) Hospital Clinic/IDIBAPS Service University of California, San Francisco of Neurology San Francisco, CA University of Barcelona Specialties: Neuroimmunology, multiple sclerosis, Barcelona, SPAIN neuromyelitis optica, experimental models of autoimmunity Dept. of Neurology Hospital of the University of Pennsylvania Philadelphia, PA 19104 Specialties: Neuro-oncology and neuroimmunology

Associate Editors

MICHAEL T. HENEKA, MD DENNIS KOLSON, MS, FRIEDEMANN PAUL, MD MARINOS C. DALAKAS, MD, Chair, Dept. of MD, PhD Charité University Medicine FAAN Neurodegenerative Disease University of Pennsylvania Berlin Professor of Neurology and Geriatric Psychiatry Dept. of Neurology (endowed Chair) NeuroCure Clinical Research Philadelphia, PA University of Bonn Center and Experimental and Director, Neuromuscular Bonn, GERMANY Specialty: Neurovirology Clinical Research Center, Max Division Delbrueck Center for Molecular Specialties: Neurodegenerative and Thomas Jefferson University Medicine and Charité – cerebrovascular diseases Philadelphia, PA University Medicine Berlin Berlin, GERMANY Specialties: Neuromuscular disorders, autoimmune neurology, Specialties: Neuroimmunology, immunotherapies multiple sclerosis, neuromyelitis optica, neuroimaging, optical coherence tomography

1 Editorial Board • Neurology: Neuroimmunology & Neuroinflammation

ROHIT AGGARWAL, MD, MS SERGIO BARANZINI, PhD SUSANNE BENSELER, MD, PhD JEFFREY L. BENNETT, SÉVERINE BOILLÉE, PhD Dept. of Medicine Dept. of Neurology Pediatric Rheumatology MD, PhD, FAAN INSERM U1127 Division of Rheumatology and University of California Alberta Children’s Hospital University of Colorado Denver UPMC Sorbonne Universities Clinical Immunology San Francisco Calgary, AB, CANADA Dept. of Neurology ICM Institute University of Pittsburgh San Francisco, CA Aurora, CO Specialties: Childhood inflammatory Salpêtrière hospital Pittsburgh, PA Specialties: Multiple sclerosis, brain diseases, vascular stroke, Specialties: Neuroimmunology, Paris, FRANCE Specialties: Rheumatology, genomics, systems biology, immunotherapy, CNS vasculitis, rare neuromyelitis optica, multiple specific disease: polymyositis and bioinformatics, immunology diseases research methodology sclerosis, B cell immunology, Specialties: ALS, motor neuron dermatomyositis neuro-ophthalmology degeneration, microglia

MATTHIS C. BROUWER, WOLFGANG BRÜCK, MD DAVID B. CLIFFORD, MD, FAAN RUSSELL C. DALE, MBCHB, OSCAR H. DEL BRUTTO, MD MD, PhD University Medical Center Dept. of Neurology and Medicine MRCP, PhD School of Medicine Dept. of Neurology Göttingen Washington University, St. Louis The Children’s Hospital Universidad Espiritu Santo– Academic Medical Center Göttingen, GERMANY St. Louis, MO at Westmead Ecuador Amsterdam, Samborondon, ECUADOR Specialties: Multiple sclerosis and Specialties: Neurologic infectious University of Sydney THE NETHERLANDS other neuroinflammatory disorders disease, neuropharmacology, HIV, Clinical School Specialties: Neurocysticercosis, Specialties: Neurologic infectious PML, Alzheimer disease epidemiology diseases, bacterial meningitis, brain Westmead, AUSTRALIA abscess, HIV, encephalitis Specialties: Pediatric neuroimmunology, pediatric movement disorders

2 Editorial Board • Neurology: Neuroimmunology & Neuroinflammation

THOMAS G. FORSTHUBER, MD KAZUO FUJIHARA, MD JEFFREY M. GELFAND, MD, JOSEPH EL KHOURY, MD MARKUS P. KUMMER, PhD University of Texas, Dept. of Multiple Sclerosis MAS, FAAN Massachusetts General Klinische Neurowissenschaften San Antonio Therapeutics University of California, Hospital Klinik and Poliklinik für San Antonio, TX San Francisco Harvard Medical School Neurologie Fukushima Medical University Charlestown, MA Specialties: Neuroimmunology, School of Medicine MS and Neuroinflammation AbbVie Deutschland GmbH MS, EAE Center, Division of Specialties: Infectious diseases, & Co. KG MS & NMO Center Neuroinflammation and Glial neurodegeneration, Alzheimer Ludwigshafen, GERMANY disease, microglia, innate immunity Southern TOHOKU Research Biology, Dept. of Neurology Specialties: Basic research in Institute for Neuroscience and Weill Institute for Alzheimer disease, diagnostic, Fukushima, JAPAN Neurosciences cell-based assays, transfection, Specialties: Neuroimmunology, San Francisco, CA retrovirus neuromyelitis optica spectrum Specialities: Neuroinflammation, disorders, multiple sclerosis, autoimmune neurology, autoimmune encephalitis neuroimmunology, multiple sclerosis, leukoencephalopathy, neurodegenerative disease, diagnostics, therapeutics, clinical research, clinical trials, medical education

JUN LI, MD, PHD, FAAN, ANDREW MCKEON, MD, LIN MEI, MD, PhD RICHARD M. RANSOHOFF, MD CHRISTOPHER POWER, MD FANA D(ABMLI) Dept. of Neurosciences Visiting Scientist, Dept of Cell University of Alberta Professor and Chairman, Depts. of Neurology, and Cleveland Brain Health Initiative Biology Depts. of Medicine (Neurology), Department of Neurology, Laboratory Medicine and School of Medicine Medical Microbiology & Harvard Medical School Pathology Immunology, and Psychiatry Scientific Director of Case Western Reserve University Boston, MA Mayo Clinic Translational Neuroscience Cleveland, OH Specialties: Neuroinflammation, 6-11 Heritage Medical Rochester, MN Initiative, Specialty: Molecular mechanisms neuroimmunology, Research Centre Chief in Neurology, Specialties: Autoimmune neurology, of neuromuscular disorders neurodegeneration University of Alberta paraneoplastic neurological Edmonton, AB, CANADA Wayne State University School disorders, clinical laboratory of Medicine and Detroit Medical immunology Specialties: NeuroAIDS- Center neurovirology, MS-neuroimmunology Detroit, MI Specialty: Neuromuscular disease

3 Editorial Board • Neurology: Neuroimmunology & Neuroinflammation

CHRISTINE STADELMANN, MD ISRAEL STEINER, MD LAWRENCE STEINMAN, JESPER TEGNÉR, PhD, MSC SILVIA N. TENEMBAUM, MD Institute of Neuropathology Rabin Medical Center MD, FAAN Unit of Computational Medicine National Pediatric Hospital University Medical Center Dept. of Neurology Stanford University Center for Molecular Medicine Dr. J.P. Garrahan Goettingen Petach Tikva, ISRAEL School of Medicine Dept. of Neurology L8:05 Karolinska University Dept. of Neurology and Buenos Aires, ARGENTINA Goettingen, GERMANY Specialties: Neuroinfections, Hospital neuroimmunology Neurological Sciences Specialties: Pediatric Specialties: Neuroimmunology, Solna, SWEDEN Beckman Center for Molecular neuroimmunology, multiple neuropathology, multiple sclerosis, Medicine Specialties: Bioinformatics, sclerosis, neuromyelitis optica neuromyelitis optica, models of CNS Stanford, CA genomics, neuroscience, molecular spectrum disorders, ADEM, optic autoimmunity and demyelination biology, cell biology, genetics neuritis, pediatric neuroimaging Specialties: Inflammation, neuromyelitis optica, multiple sclerosis, pediatric

MAARTEN J. TITULAER, ARI WAISMAN, MD HUGH J. WILLISON, GREGORY WU, MD, PhD MD, PhD University Medical Center Mainz MBBS, PhD Washington University Erasmus University Institute for Molecular Medicine University of Glasgow College School of Medicine Medical Center Mainz, GERMANY of Medical, Veterinary and Life Dept. of Neurology Dept. of Neurology Specialties: Autoimmunity, Sciences, Institute of Infection, St. Louis, MO 63110 Rotterdam, inflammation, multiple sclerosis, Immunity Inflammation Specialties: Neuroimmunology, THE NETHERLANDS psoriasis, colitis, IL-17 and Th17, University Dept. of Neurology, multiple sclerosis, experimental Specialties: Neuroimmunology, cytokine signaling and regulation, Ground Floor Neurology Block, models of autoimmunity, autoimmune and paraneoplastic immune and glia cells, blood brain optic neuritis barrier Southern General Hospital encephalitis, neuromuscular Glasgow, UNITED KINGDOM junction disorders Specialties: Autoimmune neuropathy, Guillain-Barré syndrome, glycobiology, neuroimmunology

4 Editors • Neurology: Genetics

Editor Deputy Editor

STEFAN M. PULST, MD, FAAN MASSIMO PANDOLFO, MD, FAAN University of Utah Service de Neurologie, Dept. of Neurology Hospital Erasme Salt Lake City, UT Université Libre de Bruxelles Specialties: Genetics, movement disorders Brussels, BELGIUM Specialties: Spastic paraplegia, Huntington disease, ataxia

Associate Editors

ALEXANDRA DURR, MD, PhD SUMAN JAYADEV, MD MARGHERITA MILONE, RAYMOND P. ROOS, MD, FAAN ICM and Genetic Dept. University of Washington MD, PhD University of Chicago Hopital de la Salpetriere Medicine Memory and Brain Mayo Clinic Medical Center Paris, FRANCE Wellness Center Dept. of Neurology Chicago, IL Rochester, MN Specialties: Spastic paraplegia, Harborview Medical Center Specialties: , Huntington disease, ataxia Seattle, WA Specialties: Muscular dystrophies, prion disease, neurovirology/ mitochondrial disorders, and neuroimmunology Specialties: Neurodegeneration, hereditary myopathies neuroinflammation

1 Editorial Board • Neurology: Genetics

HILARY COON, PhD GIOVANNI COPPOLA, MD CHANTAL DEPONDT, MD, PhD BRENT L. FOGEL, MD, PhD, ANTHONY J. GRISWOLD, PhD University of Utah Semel Institute for Dept. of Neurology FAAN University of Miami Miller Neuroscience and Human Hôpital Erasme David Geffen School of School of Medicine Utah Autism Research Project Behavior Medicine University of Miami, FL Salt Lake City, UT Université Libre de Bruxelles California, Los Angeles Specialties: Bioinformatics, Specialties: Biostatistics, suicide, Depts. of Psychiatry & Brussels, BELGIUM developmental disorders, Alzheimer autism spectrum disorders, Neurology Specialties: Epilepsy, UCLA Depts. of Neurology and Human Genetics disease statistical genetics, genetic David Geffen School of Medicine pharmacogenetics, ataxia, epidemiology, child psychiatry, neurogenetics Los Angeles, CA obesity, pulmonary fibrosis, nicotine #3506C Gonda Neuroscience Specialities: Neurogenetics, dependence and Genetics Research Center genomics, cerebellar ataxia, University of California spastic paraplegia, leukodystrophy, Los Angeles precision health Los Angeles, CA Specialities: Genetics, genomics, neurodegeneration

ORHUN H. KANTARCI, MD JULIE R. KORENBERG, DAVIDE PAREYSON, MD SHOJI TSUJI, MD, PhD DINEKE S. VERBEEK, Mayo Clinic MD, PhD Rare Neurodegenerative and University of Tokyo Graduate MSC, PhD Dept. of Neurology University of Utah Neurometabolic Diseases Unit School of Medicine Neurology University Medical Center Rochester, MN Salt Lake City, UT Tokyo, JAPAN Groningen Dept. of Clinical Neurosciences Specialties: Muscular dystrophies, Specialties: Pediatrics, Down Specialty: Molecular genetics Dept. of Genetics mitochondrial disorders, and syndrome, Williams syndrome IRCCS Foundation Groningen, THE NETHERLANDS hereditary myopathies C. Besta Neurological Institute Specialties: Movement disorders, Milan, ITALY with special attention on the Specialities: Inherited neuropathies, spinocerebellar ataxias spinal and bulbar muscular atrophy, clinical neurogenetics

2 Editorial Board • Neurology: Genetics

DAVID VISKOCHIL, MD, PhD JULIANE WINKELMANN, MD JUAN I. YOUNG, PhD University of Utah, Salt Lake Helmholtz Zentrum München University of Miami City, UT German Research Centre for Dept. of Human Genetics Dept. of Pediatrics~Division of Environmental Health Miami, FL 33136 Medical Genetics Director of the Institute for Specialties: Epigenetics, Salt Lake City, UT Neurogenomics pathophysiology, cognitive disorders, neurogenetics, Specialties: Molecular genetics Neuherberg, GERMANY Rett syndrome Specialty: Neurogenomics

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