Nutrigenetics of Japanese Vegetarians with Polymorphism In
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Macronutrients and Human Health for the 21St Century
nutrients Editorial Macronutrients and Human Health for the 21st Century Bernard J. Venn Department of Human Nutrition, University of Otago, Dunedin 9054, New Zealand; [email protected] Received: 30 July 2020; Accepted: 4 August 2020; Published: 7 August 2020 Abstract: Fat, protein and carbohydrate are essential macronutrients. Various organisations have made recommendations as to the energy contribution that each of these components makes to our overall diet. The extent of food refining and the ability of food systems to support future populations may also impact on how macronutrients contribute to our diet. In this Special Issue, we are calling for manuscripts from all disciplines to provide a broad-ranging discussion on macronutrients and health from personal, public and planetary perspectives. Keywords: macronutrient; fat; protein; carbohydrate; acceptable macronutrient distribution range; starch; sustainability The macronutrients, fat, protein and carbohydrate provide energy and essential components to sustain life. Fat is composed of glycerol and fatty acids; protein is an agglomeration of amino acids; and carbohydrate is simple sugars occurring either as monosaccharides or chains of connected monosaccharides (e.g., starch) whose bonds are either hydrolysed in the human small intestine to monosaccharides or are resistant to hydrolysis (dietary fibre). To maintain longevity and health, a combination of these macronutrients is required in our diet. It is elusive as to whether there is a combination of macronutrients that provides optimal health. When expressed as a percentage of energy to the diet, human populations have historically survived on diets with greatly differing proportions of these macronutrients. For example, the animal-based diet of an Alaskan Inuit group was found to comprise 33% protein, 41% fat and 26% carbohydrate [1]. -
Antimicrobial Activities of Stearidonic and Gamma-Linolenic Acids
Park et al. Botanical Studies 2013, 54:39 http://www.as-botanicalstudies.com/content/54/1/39 RESEARCH Open Access Antimicrobial activities of stearidonic and gamma-linolenic acids from the green seaweed Enteromorpha linza against several oral pathogenic bacteria Nam-Hee Park1†, Jae-Suk Choi2†, Seon-Yeong Hwang1, Yang-Chun Kim1, Yong-Ki Hong3, Kwang Keun Cho4 and In Soon Choi2,5* Abstract Background: We found that the edible green seaweed Enteromorpha linza displayed potent antimicrobial activity against Prevotella intermedia and Porphyromonas gingivalis. To elucidate the active component of E. linza, isolation procedures were performed. Results: The main active compound was isolated by polarity fractionation, Sephadex LH-20 gel chromatography, and reverse-phase high-performance liquid chromatography (RP-HPLC). The active compounds were eluted at isocratic 95% acetonitrile by RP-HPLC and identified as unsaturated fatty acids, stearidonic acid (SA, C18:4 n-3) and gamma-linolenic acid (GLA, C18:3 n-6) by gas chromatography–mass spectrometry, 1H nuclear magnetic resonance (NMR) spectroscopy, and 13C NMR spectroscopy. The yields of SA and GLA from dried seaweed tissue were 6.33 × 10-3% and 6.47 × 10-3%, respectively. The minimal inhibitory concentration values of SA and GLA were 39.06 μg/mL against P. intermedia and 9.76 μg/mL against P. gingivalis, respectively. SA and GLA were also active against several other oral pathogens, including Aggregatibacter actinomycetemcomitans, Candida albicans, Fusobacterium nucleatum subsp. vincenti, and Streptococcus mutans, at micromolar concentrations. Conclusions: These data suggest that the E. linza extracts SA and GLA are useful antimicrobial agents for the prevention and/or treatment of periodontitis. -
NUTRITION DIET PROJECT Instructions TOTAL POINTS / 60
NUTRITION DIET PROJECT ▪ 9.2C Analyze current research and scientific studies to interpret nutritional principles, research the accuracy of health claims for a variety of processed foods and/or dietary supplements, and analyze personal daily diet to determine if meeting daily values for amino acids, vitamins, and minerals. ▪ 10.1C Distinguish between facts and myths regarding nutrition practices, products, and physical performance. Activity Grade Level Summative Assessment Diet Project 9th & 10th Summative Rubric Instructions 1) Using the time given in class, you are to research your assigned diet plan to find the following information from the rubric. You will also design an interactive visual display based on what you find. Your visual display should have all of the content from the rubric present in a creative manner. You will use this during your group presentation. 2) After you are finished with your research and your visual display, your group must grade your diet with the “Is Your Diet Healthy?” 3) After completing this step, you are going to use the Venn Diagram to compare and contrast your assigned diet with the governmental guidelines of the MyPlate. 4) You must use at least 4 valid references. Reference List 1. _________________________________________________________________ 2. _________________________________________________________________ 3. _________________________________________________________________ 4. _________________________________________________________________ Group Members: _______________________________ -
Comparison of Fatty Acid Profiles in Vegans and Omnivores
Aus dem Bundesinstitut für Risikobewertung und Aus dem Institut für Sozialmedizin, Epidemiologie und Gesundheitsökonomie der Medizinischen Fakultät Charité – Universitätsmedizin Berlin DISSERTATION Comparison of fatty acid profiles in vegans and omnivores zur Erlangung des akademischen Grades Doctor medicinae (Dr. med.) vorgelegt der Medizinischen Fakultät Charité – Universitätsmedizin Berlin von Alessa Longrée aus Mülheim an der Ruhr Datum der Promotion: 18.12.2020 Table of Contents i Table of Contents I. List of tables ........................................................................................................... iv II. List of figures ........................................................................................................... v III. List of abbreviations .............................................................................................. vi 1 Abstract ..................................................................................................................... 1 2 Zusammenfassung................................................................................................... 2 3 Introduction .............................................................................................................. 4 Definition of veganism and veganism in Germany ............................................ 4 Potential health benefits of vegan diets ............................................................. 5 Risk factors for cardiometabolic diseases ................................................... -
Value of Wholegrain Rice in a Healthy Human Nutrition
agriculture Review Value of Wholegrain Rice in a Healthy Human Nutrition Marina Carcea Research Centre on Food and Nutrition (CREA-AN), Council for Agricultural Research and Economics (CREA), Via Ardeatina, 546, 00178 Rome, Italy; [email protected]; Tel.: +39-06-5149-4429 Abstract: Rice is one of the most widely consumed cereals in the world. The husks of harvested, unprocessed rice are not digested by humans and need to be removed to obtain edible grains, whereas the bran can be partially (brown rice) or totally removed (white rice). Brown rice is a wholegrain cereal and, as such, is known to have beneficial effects on human health. Recent epidemiological studies have shown that the consumption of whole grains can reduce the risk of metabolic disorders, cardiovascular diseases, and some types of cancer. However, white rice is preferred for reasons connected to appearance, taste, palatability, ease of cooking, tradition, safety, shelf-life, and lack of awareness about its benefits and availability. In this review, the latest scientific reports regarding the nutritional composition of brown rice and the evolution of the technology for its production will be briefly reviewed together with research on nutritional implications of brown rice consumption also in relation to cancer development in humans. A specific chapter is devoted to pigmented rice which, thanks to its composition, has attracted the growing interest of consumers worldwide. The need for further studies to help promote the consumption of wholegrain rice are also discussed. Keywords: brown rice; nutritional quality; brown rice technology; pigmented rice; glycemic re- sponse; cancer Citation: Carcea, M. -
Complementary Analytical Platforms of NMR Spectroscopy and LCMS Analysis in the Metabolite Profiling of Isochrysis Galbana
marine drugs Article Complementary Analytical Platforms of NMR Spectroscopy and LCMS Analysis in the Metabolite Profiling of Isochrysis galbana Muhammad Safwan Ahamad Bustamam 1, Hamza Ahmed Pantami 2 , Awanis Azizan 1 , Khozirah Shaari 1,2, Chong Chou Min 3, Faridah Abas 1 , Norio Nagao 3, Maulidiani Maulidiani 4, Sanjoy Banerjee 1, Fadzil Sulaiman 1 and Intan Safinar Ismail 1,2,* 1 Natural Medicine and Products Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia; [email protected] (M.S.A.B.); [email protected] (A.A.); [email protected] (K.S.); [email protected] (F.A.); [email protected] (S.B.); [email protected] (F.S.) 2 Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia; [email protected] 3 Department of Aquaculture, Faculty of Agriculture, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia; [email protected] (C.C.M.); [email protected] (N.N.) 4 Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, Kuala Nerus 21030, Terengganu, Malaysia; [email protected] * Correspondence: safi[email protected]; Tel.: +60-3-9769-7492 Abstract: This study was designed to profile the metabolites of Isochrysis galbana, an indigenous and Citation: Bustamam, M.S.A.; less explored microalgae species. 1H Nuclear Magnetic Resonance (NMR) spectroscopy and Liquid Pantami, H.A.; Azizan, A.; Shaari, K.; Chromatography-Mass Spectrometry (LCMS) were used to establish the metabolite profiles of five Min, C.C.; Abas, F.; Nagao, N.; different extracts of this microalga, which are hexane (Hex), ethyl acetate (EtOAc), absolute ethanol Maulidiani, M.; Banerjee, S.; (EtOH), EtOH:water 1:1 (AqE), and 100% water (Aq). -
Hernandez V. Mimi's Rock, Corp
Case 3:21-cv-04065-JCS Document 1 Filed 05/28/21 Page 1 of 38 KUZYK LAW, LLP 1 Michael D. Braun (SBN 167416) 2 [email protected] 1999 Avenue of the Stars, Ste. 1100 3 Los Angeles, CA 90067 Telephone: (213) 401-4100 4 Facsimile: (213) 401-0311 5 Counsel for Plaintiff 6 7 UNITED STATES DISTRICT COURT 8 NORTHERN DISTRICT OF CALIFORNIA OAKLAND DIVISION 9 10 11 ALFREDO HERNANDEZ on behalf of CASE NO.: himself and all others similarly situated, 12 CLASS ACTION Plaintiff, COMPLAINT FOR DAMAGES, 13 v. EQUITABLE, DECLARATORY, AND INJUNCTIVE RELIEF 14 MIMI’S ROCK, CORP. DEMAND FOR JURY TRIAL 15 Defendant 16 17 18 19 20 21 22 23 24 25 26 27 28 COMPLAINT FOR DAMAGES, EQUITABLE, DECLARATORY, AND INJUNCTIVE RELIEF Case 3:21-cv-04065-JCS Document 1 Filed 05/28/21 Page 2 of 38 1 Plaintiff Alfredo Hernandez (“Plaintiff”), on behalf of himself and all others similarly 2 situated, brings this class action against Mimi’s Rock Corp. (“MRC” or “Defendant”), and on the 3 basis of personal knowledge, information and belief, and the investigation of counsel, alleges as 4 follows: 5 INTRODUCTION 6 7 1. This is a proposed class action on behalf of a nationwide and California class of 8 consumers seeking redress for Defendant’s deceptive practices associated with the advertising, 9 labeling and sale of its Dr. Tobias Omega 3 Fish Oil Triple Strength dietary supplement (“Product” 10 or “Supplement”). 11 2. Fish is a major source of healthful long-chain omega-3 fats and are rich in other 12 nutrients, high in protein, and low in saturated fat. -
Brown Seaweed Padina Gymnospora Is a Prominent Natural
Revista Brasileira de Farmacognosia 26 (2016) 714–719 ww w.elsevier.com/locate/bjp Original Article Brown seaweed Padina gymnospora is a prominent natural wound-care product a a a a b,c Alegna P. Baliano , Elisangela F. Pimentel , Aline R. Buzin , Tainã Z. Vieira , Wanderson Romão , b a a a d Lilian V. Tose , Dominik Lenz , Tadeu U. de Andrade , Marcio Fronza , Tamara P. Kondratyuk , a,∗ Denise C. Endringer a Laboratório de Obtenc¸ ão e Análise de Produtos Naturais, Programa de Pós-graduac¸ ão em Ciências Farmacêuticas, Universidade Vila Velha, Vila Velha, ES, Brazil b Departamento de Química, Universidade Federal do Espirito Santo, Vitória, ES, Brazil c Instituto Federal do Espírito Santo, Campus Vila Velha, Vila Velha, ES, Brazil d Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo Hawaii, USA a b s t r a c t a r t i c l e i n f o Article history: Seaweeds are related to anti-inflammatory, anti-bacterial and anti-noceptive effects. This work aimed Received 13 April 2016 to verify the potential of seaweed Padina gymnospora (Kützing) Sonder 1871 to improve wound healing Accepted 11 July 2016 in vitro. P. gymnospora was collected at a bethonic area in Espirito Santo. Methanolic extract of P. gym- Available online 16 August 2016 nospora was obtained by percolation. To determine cytotoxicity, colorimetric MTT tests were performed against normal fibroblasts (L929), macrophages (RAW 264.7) and human ovarian carcinoma (OVCAR-3) Keywords: −1 cell lines using concentration range of 12–110 g ml . To evaluate in vitro wound healing, monolayer of Padina gymnospora −1 fibroblasts L929 was seeded and artificial wounded. -
Fatty-Acids-Cardiovascular-Disease Research-Protocol
Evidence-based Practice Center Systematic Review Protocol Project Title: Omega 3 Fatty Acids and Cardiovascular Disease -- Update I. Background and Objectives for the Systematic Review The Office of Dietary Supplements (ODS), the National Institutes of Health (NIH), has a long history of commissioning AHRQ-based systematic reviews and research methodology reports for nutrient-related topics (http://ods.od.nih.gov/Research/Evidence-Based_Review_Program.aspx). Omega-3 fatty acids (n-3 FA) and their potential relationship to a broad range of health outcomes formed the basis for nine of these systematic reviews published between 2004 and 2006 and also served as examples for several methodological reports (1-14). The purpose of the current systematic review is twofold: a) to update an earlier review of the state-of-the science on the topic of the effects of n-3 FA on cardiovascular disease (CVD) (15), and b) to use this new review to collect additional information that would enhance the usefulness of this report for policy and clinical applications. Since the publication of the original n-3 FA systematic reviews in the mid-2000s the topic of n-3 FA and health has remained controversial and dynamic. This topic has been evaluated by several expert panels as they were considering whether recommendations or reference values for intakes of n-3 FA were warranted, either through naturally occurring sources of n-3 FA (e.g., fish consumption) and/or through the use of dietary supplements and fortified foods (16-19). The n-3 FA (including alpha- linolenic acid [ALA], stearidonic acid [SDA], eicosapentaenoic acid [EPA], docosapentaenoic acid [DPA], and docosahexaenoic acid [DHA]) are a group of long chain polyunsaturated fatty acids that serve as precursors for bioactive compounds such as eicosanoids and are integral components of cell membranes. -
Jns Journal of Nutritional Science
JNS JOURNAL OF NUTRITIONAL SCIENCE REVIEW ARTICLE https://doi.org/10.1017/jns.2017.62 . Long-chain n-3 PUFA in vegetarian women: a metabolic perspective Graham C. Burdge1*, Sze-Yen Tan2 and Christiani Jeyakumar Henry2 1Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK 2Clinical Nutrition Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, Singapore and Department of Biochemistry, National University of Singapore, Singapore (Received 5 June 2017 – Final revision received 14 September 2017 – Accepted 9 October 2017) https://www.cambridge.org/core/terms Journal of Nutritional Science (2017), vol. 6, e58, page 1 of 8 doi:10.1017/jns.2017.62 Abstract Vegetarian diets have been associated with health benefits, but paradoxically are low in EPA and DHA which are important for development, particularly of the central nervous system, and for health. Humans have limited capacity for synthesis of EPA and DHA from α-linolenic acid, although this is greater in women than men. Oily fish and, to a lesser extent, dairy foods and meat are the primary sources of EPA and DHA in the diet. Exclusion of these foods from the diet by vegetarians is associated consistently with lower EPA and DHA status in vegetarian women compared with omnivores. The purpose of the present review was to assess the impact of low EPA and DHA status in vegetarian pregnancies on the development and health of children. EPA and DHA status was lower in breast milk and in infants of vegetarian mothers than those born to omnivore mothers, which suggests that in the absence of pre-formed dietary EPA and DHA, synthesis from α-linolenic acid is an important process in determining maternal EPA and DHA status in pregnancy. -
Omega-3, Omega-6 and Omega-9 Fatty Acids
Johnson and Bradford, J Glycomics Lipidomics 2014, 4:4 DOI: 0.4172/2153-0637.1000123 Journal of Glycomics & Lipidomics Review Article Open Access Omega-3, Omega-6 and Omega-9 Fatty Acids: Implications for Cardiovascular and Other Diseases Melissa Johnson1* and Chastity Bradford2 1College of Agriculture, Environment and Nutrition Sciences, Tuskegee University, Tuskegee, Alabama, USA 2Department of Biology, Tuskegee University, Tuskegee, Alabama, USA Abstract The relationship between diet and disease has long been established, with epidemiological and clinical evidence affirming the role of certain dietary fatty acid classes in disease pathogenesis. Within the same class, different fatty acids may exhibit beneficial or deleterious effects, with implications on disease progression or prevention. In conjunction with other fatty acids and lipids, the omega-3, -6 and -9 fatty acids make up the lipidome, and with the conversion and storage of excess carbohydrates into fats, transcendence of the glycome into the lipidome occurs. The essential omega-3 fatty acids are typically associated with initiating anti-inflammatory responses, while omega-6 fatty acids are associated with pro-inflammatory responses. Non-essential, omega-9 fatty acids serve as necessary components for other metabolic pathways, which may affect disease risk. These fatty acids which act as independent, yet synergistic lipid moieties that interact with other biomolecules within the cellular ecosystem epitomize the critical role of these fatty acids in homeostasis and overall health. This review focuses on the functional roles and potential mechanisms of omega-3, omega-6 and omega-9 fatty acids in regard to inflammation and disease pathogenesis. A particular emphasis is placed on cardiovascular disease, the leading cause of morbidity and mortality in the United States. -
The Polar Lipidome of Cultured Emiliania Huxleyi: a Source of Bioactive Lipids with Relevance for Biotechnological Applications
biomolecules Article The Polar Lipidome of Cultured Emiliania huxleyi: A Source of Bioactive Lipids with Relevance for Biotechnological Applications Susana S. Aveiro 1 ,Tânia Melo 2, Ana Figueiredo 1, Pedro Domingues 1 , Hugo Pereira 3, Inês B. Maia 4 , Joana Silva 5, M. Rosário Domingues 1,2 , Cláudia Nunes 6 and Ana S. P.Moreira 1,6,* 1 Mass Spectrometry Center, LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal; [email protected] (S.S.A.); [email protected] (A.F.); [email protected] (P.D.); [email protected] (M.R.D.) 2 ECOMARE, CESAM—Centre for Environmental and Marine Studies, Department of Chemistry, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal; [email protected] 3 Green Colab—Associação Oceano Verde, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal; [email protected] 4 Centre of Marine Sciences, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal; [email protected] 5 Allmicroalgae Natural Products S.A., Apartado 9, 2449-909 Pataias, Portugal; [email protected] 6 CICECO—Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal; [email protected] * Correspondence: [email protected]; Tel.: +351-234-401-505 Received: 14 September 2020; Accepted: 5 October 2020; Published: 12 October 2020 Abstract: Polar lipids from microalgae have aroused greater interest as a natural source of omega-3 (n-3) polyunsaturated fatty acids (PUFA), an alternative to fish, but also as bioactive compounds with multiple applications.