COLQ (NM 080539) Human Untagged Clone Product Data

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for SC305790

COLQ (NM_080539) Human Untagged Clone Product data:

Product Type: Expression Plasmids Product Name: COLQ (NM_080539) Human Untagged Clone Tag: Tag Free Symbol: COLQ Synonyms: CMS5; EAD Vector: pCMV6-Entry (PS100001) E. coli Selection: Kanamycin (25 ug/mL) Cell Selection: Neomycin Fully Sequenced ORF: >NCBI ORF sequence for NM_080539, the custom clone sequence may differ by one or more nucleotides

ATGGTTGTCCTGAATCCAATGACTTTGGGAATTTATCTTCAGCTTTTCTTCCTCTCTATCGTGTCTCAGC CGACTTTCATCAACAGCGTTCTTCCAATCTCAGCAGCCCTTCCCAGCCTGGATCAGAAGAAGCGTGGTGG CCACAAAGCATGCTGCCTGCTGACGCCTCCTCCACCACCACTGTTCCCACCACCATTCTTCAGAGGTGGC CGAAGTCCGGGTCCACCGGGGCTTCCTGGCAAGACAGGACCAAAGGGAGAAAAGGGGGAGCTTGGCCGAC CAGGAAGGAAGGGTAGACCTGGCCCCCCAGGTGTTCCTGGCATGCCTGGGCCCATCGGTTGGCCAGGCCC TGAAGGACCCAGGGGTGAAAAAGGTGACCTGGGTATGATGGGCTTGCCAGGGTCAAGAGGACCAATGGGC TCCAAGGGCTACCCTGGATCCAGAGGGGAAAAGGGATCCAGAGGTGAAAAGGGTGACCTGGGTCCCAAAG GAGAAAAGGGTTTCCCAGGATTTCCTGGAATGTTGGGGCAGAAAGGTGAAATGGGTCCAAAAGGTGAACC TGGGATAGCAGGACACCGAGGACCCACAGGAAGACCAGGAAAACGAGGCAAGCAGGGACAGAAAGGGGAT AGTGGAGTTATGGGCCCACCAGGCAAGCCTGGGCCTTCTGGTCAACCTGGCCGTCCGGGGCCCCCAGGCC CCCCACCTGCAGGACAACTTATAATGGGACCCAAAGGGGAAAGAGGATTTCCCGGGCCTCCAGGAAGATG TCTTTGTGGACCCACTATGAATGTGAATAACCCTTCCTACGGGGAATCTGTGTATGGGCCCAGTTCCCCG CGAGTTCCTGTGATTTTTGTGGTCAACAACCAGGAGGAGCTTGAGAGGCTGAACACCCAAAACGCCATTG CCTTCCGCAGAGACCAGAGATCTCTGTACTTCAAGGACAGCCTTGGCTGGCTCCCCATCCAGCTGACCCC TTTCTACCCTGTGGATTACACTGCAGACCAGCACGGCACCTGTGGGGATGGGCTCCTGCAGCCTGGGGAG GAGTGTGACGACGGTAACAGCGATGTGGGTGACGACTGCATCCGCTGTCACCGTGCCTACTGTGGAGATG GTCACCGGCATGAGGGTGTGGAGGACTGTGACGGCTCTGACTTTGGCTACCTGACATGCGAGACCTATCT CCCTGGGTCATATGGAGACCTGCAATGCACCCAGTACTGCTACATCGACTCCACGCCCTGCCGCTACTTC ACCTGA

Restriction Sites: SgfI-MluI ACCN: NM_080539

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 COLQ (NM_080539) Human Untagged Clone – SC305790

OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. RefSeq: NM_080539.3, NP_536800.2 RefSeq Size: 2905 bp RefSeq ORF: 1266 bp Locus ID: 8292 UniProt ID: Q9Y215 Protein Families: Druggable Genome, Transmembrane Gene Summary: This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (III) is the only variant missing exon 3. Exon 3 encodes the proline-rich attachment domain; as a result, isoform III is the only isoform lacking this domain.