MRPL15 Antibody Cat. No.: 15-522

MRPL15 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse

Recombinant fusion containing a sequence corresponding to amino acids 1-296 of IMMUNOGEN: human MRPL15 (NP_054894.1).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:500 - 1:2000

POSITIVE CONTROL: 1) U-87MG

2) HeLa

3) MCF7

4) A-549

5) Mouse heart

6) Mouse kidney

PREDICTED MOLECULAR Observed: 36kDa WEIGHT:

Properties

September 26, 2021 1 https://www.prosci-inc.com/mrpl15-antibody-15-522.html PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: MRPL15

HSPC145, L15mt, MRP-L15, MRP-L7, RPML7, 39S L15, mitochondrial, ALTERNATE NAMES: mitochondrial large ribosomal subunit protein uL15m

GENE ID: 29088

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Mammalian mitochondrial ribosomal are encoded by nuclear and help in protein synthesis within the . Mitochondrial (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic BACKGROUND: ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by . This encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A corresponding to this gene is found on 15q.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 26, 2021 2 https://www.prosci-inc.com/mrpl15-antibody-15-522.html