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Chemistry of Functional Organic Chemicals France-Japan Joint Forum Chemistry of Functional Organic Chemicals International Year of Chemistry – 2011 – 23 - 25 juin 2011 ISIS Université de Strasbourg France-Japan Joint Forum on Chemistry of Functional Organic Chemicals for Celebrating International Year of Chemistry – 2011 – organized by UDS, CNRS and JSPS With the support of: Région Alsace Conseil Général du Bas-Rhin Communauté Urbaine de Strasbourg Consulat Général du Japon à Strasbourg Scientific Coordinators: Jean-Pierre Sauvage, Kazuhiko Saigo Organizers : Jean-Marc Planeix, Yoichi Nakatani, Gilberte Chambaud, Régis Réau, Pascal Breuilles Secretariat: Francine Pinard, Satoko Tada, Bertrand Pinard, Mina Saito Video of the forum is available on Canal U, the web-TV of French Ministry of Higher Education and Research: http://www.canalc2.tv/ Program Timing Schedule Day One – Thursday 23rd June 2011 08:00 Registration Institut de Science et d'Ingénierie Supramoléculaires (ISIS), Université de Strasbourg (UDS) 08:40-09:10 Welcome remarks Chairpersons Jean-Marc Planeix, Yoichi Nakatani - Éric Westhof Vice-President "Recherche et formation doctorale", University of Strasbourg - Hiroshi Karube Consul General of Japan in Strasbourg - Régis Réau Director, Institute of Chemistry, CNRS - Henri Dreyfus Representative of the Mayor of Strasbourg - François Loos Vice-President, Conseil Régional d’Alsace - Kazuhiko Saigo Former Chair, 116th Committee of JSPS Vice-President, Kochi University of Technology - Motoyuki Ono President, Japan Society for the Promotion of Science (JSPS) 09:10-10:40 1st Session Chairperson: Paolo Samori - Jean-Marie Lehn “Perspectives in Chemistry: Towards Adaptive Chemistry” - Masakatsu Shibasaki “Recent Progress in Cooperative Asymmetric Catalysis” 10:40-11:00 Coffee break 11:00-12:30 1st Session Chairperson: Paolo Samori - Clément Sanchez “Rational Design of Nanostructured and Hierarchically structured Functional Solids” - Susumu Kitagawa “Gas Science/Technology of Porous Coordination Polymers” 1 12:30 Photo session 12:40-13:45 Lunch time ISIS 13:45-15:15 2nd Session Chairperson: Pierre Rabu - Jean-François Nirengarten “Fullerene-containing nanostructures for materials science and biological applications” - Masahiko Yamaguchi “Organic Synthesis from Small Helical Molecules towards Materials” 15:15-15:45 Coffee break 15:45-17:15 2nd Session Chairperson: Pierre Rabu - Wais Hosseini “Controlling movements in molecular turnstiles” - Takashi Kato “Self-Assembly of Molecular-Based Functional Materials” Day Two – Friday 24th June 2011 08:00 Registration ISIS 08:30-10:00 3rd Session Chairperson: Pierre Braunstein - Marc Fontecave “Lessons from Nature: highly selective radical-based chemistry in metabolic and biosynthetic pathways” - Yoshihisa Inoue “Bio-Supramolecular Photochirogenesis” 10:00-10:20 Coffee break 10:20-11:50 3rd Session Chairperson: Pierre Braunstein - Mihai Barboiu “Dynamic Interactive Systems – toward natural selection of functions” - Koji Suzuki “Creation of Sensing Molecules and Materials for Chemical Sensors” 11:50-13:00 Lunch time ISIS 13:00-15:15 4th Session Chairperson: Jean Weiss - Olivia Reinaud “Biomimetic molecular funnels with hat and boots” - Norio Teramae “Molecule Recognition Based on Abasic-site-binding Fluorescent Ligands” - Raymond Ziessel “Boron Dipyrromethene Dyes: A Toolbox for Molecular Photonics and Light Emitting Devices” 2 15:15-15:45 Coffee break 15:45-18:00 4th Session Chairperson: Jean Weiss - Yoshiki Chujo “Mainchain-Type Organoboron Polymers: Synthesis and Photoluminescence Properties” - Alain Deffieux “Ring Polymers and Related Chain Architectures: Synthesis and Molecular Imaging” - Takao Ikariya “Greener Molecular Transformation with Bifunctional Molecular Catalysts” Day Three – Saturday 25th June 2011 07:45 Registration ISIS 08:00-09:30 5th Session Chairperson: Dominique Matt - Didier Astruc “Green Catalysis inside Dendritic Nanoreactors” - Atsushi Takahara “Dynamics and Functional Properties of Precisely Designed Polymer Brushes” 09:30-09:45 Coffee break 09:45-11:15 5th Session Chairperson: Dominique Matt - Régis Réau “Organophosphorus and Organometallic Chemistry for the Design of pi-Conjugated Systems” - Tamejiro Hiyama “Carbon-Carbon Bond Forming Strategy through C–H and C–C Activation” 11:15-12:00 Special lecture - George M. Whitesides “Charge Transport by Tunneling through Self-Assembled Monolayers (SAMs)” 12:00-12:10 Closing remarks - Jean-Pierre Sauvage - Kazuhiko Saigo - Jean-Marc Planeix - Yoichi Nakatani 3 Forum Abstracts and CVs (Speakers) 4 1st Session Perspectives in Chemistry: Towards Adaptive Chemistry Jean-Marie Lehn ISIS, Université de Strasbourg and Collège de France, Paris Supramolecular chemistry explores the design of systems undergoing self-organization, i.e. systems capable of generating well-defined functional supramolecular architectures by self-assembly from their components, thus behaving as programmed chemical systems. Chemistry may therefore be considered as an information science, the science of informed matter . The design of molecular information-controlled functional self-organizing systems also provides an original approach to nanoscience and nanotechnology Supramolecular chemistry is intrinsically a dynamic chemistry in view of the lability of the interactions connecting the molecular components of a supramolecular entity and the resulting ability of supramolecular species to exchange their constituents. The same holds for molecular chemistry when the molecular entity contains covalent bonds that may form and break reversibility, so as to allow a continuous change in constitution by reorganization and exchange of building blocks. These features define a Constitutional Dynamic Chemistry (CDC) on both the molecular and supramolecular levels. CDC takes advantage of dynamic constitutional diversity to allow variation and selection in response to either internal or external factors to achieve adaptation. The merging of the features: - information and programmability, - dynamics and reversibility, -constitution and structural diversity, points towards the emergence of adaptive and evolutive chemistry. Lehn, J.-M., Supramolecular Chemistry: Concepts and Perspectives, VCH Weinheim, 1995. Lehn, J.-M., Toward complex matter: Supramolecular chemistry and self-organization, Proc. Natl. Acad. Sci. USA, 2002, 99, 4763. Lehn, J.-M., From supramolecular chemistry towards constitutional dynamic chemistry and adaptive chemistry, Chem. Soc. Rev., 2007, 36, 151. 5 Jean-Marie Lehn Professor ISIS – Université de Strasbourg Address: 8, allee Gaspard Monge, 67000 Strasbourg, France Phone: +33 (0)3 68 85 51 45 /44 Fax: 33 (0)3 68 85 51 40 E-mail: [email protected] http://www-isis.u-strasbg.fr Jean-Marie LEHN was born in Rosheim, France in 1939. In 1970 he became Professor of Chemistry at the Université Louis Pasteur in Strasbourg and from 1979 to 2010 he was Professor at the Collège de France in Paris. He is presently Professor Emeritus at the University of Strasbourg. He shared the Nobel Prize in Chemistry in 1987 for his studies on the chemical basis of “molecular recognition” (i.e. the way in which a receptor molecule recognizes and selectively binds a substrate), which also plays a fundamental role in biological processes. Over the years his work led him to the definition of a new field of chemistry, which he has proposed calling “supramolecular chemistry” as it deals with the complex entities formed by the association of two or more chemical species held together by non-covalent intermolecular forces, whereas molecular chemistry concerns the entities constructed from atoms linked by covalent bonds. Subsequently, the area developed into the chemistry of "self-organization" processes and more recently towards "adaptive chemistry". Author of more than 850 scientific publications, Lehn is a member of many academies and institutions. He has received numerous international honours and awards. 6 1st Session Recent Progress in Cooperative Asymmetric Catalysis Masakatsu Shibasaki Institute of Microbial Chemistry, Tokyo We have been very much interested in highly atom economical asymmetric catalysis, that is, catalytic asymmetric induction just through proton transfer conditions. To realize asymmetric catalysis of this type, we believe that asymmetric two-center catalysis or cooperative asymmetric catalysis plays a key role. In this symposium, practical catalytic asymmetric synthesis of ranirestat (a highly potent aldose reductase inhibitor under clinical development for the treatment of diabetic complications), α β3-3-adrenoreceptor agonist, R207910 (a promising potent antitubeculosis drug candidate of both drug-sensitive and drug-resistant Mycobacterium tubeculosis), and development of direct catalytic asymmetric aldol reaction of thioamides is presented. 7 Masakatsu Shibasaki Director: Institute of Microbial Chemistry Emeritus Professor: The University of Tokyo & Hokkaido University Address: 3-14-23, Kamiosaki, Shinagawa-ku, Tokyo, 141-0021, Japan Phone: +81 (0)3 34 47 77 79 Fax: +81 (0)3 34 41 75 89 E-mail: [email protected] http://www.bikaken.or.jp/research/group/shibasaki/shibasaki- lab/index.html Masakatsu Shibasaki was born in 1947 in Saitama, Japan, and received his PhD. from the University of Tokyo in 1974 under the direction of the late Professor Shun-ichi Yamada before doing postdoctoral studies with Professor E. J. Corey at Harvard University. In 1977 he returned to Japan and joined Teikyo University as an associate professor. In 1983 he moved to Sagami Chemical Research Center as a group
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