DOCSLIB.ORG

Sodium Disulfite/Bisulfite Allergy Manifesting from Dish Soap: Not Limited to Hairdressing Or Food Industries Sara A

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Sodium Disulfite/Bisulfite Allergy Manifesting from Dish Soap: Not Limited to Hairdressing Or Food Industries Sara A Sodium Disulfite/Bisulfite Allergy Manifesting from Dish Soap: Not Limited to Hairdressing or Food Industries Sara A. Kullberg, BA1,2; Sara A. Hylwa, MD1,3 1. Park Nicollet Contact Dermatitis Clinic; 2. University of Minnesota Medical School; and 3. University of Minnesota Department of Dermatology, Minneapolis, MN Background Patch Testing Discussion • Sulfites (sodium sulfite, sodium bisulfite, Final patch test reading (standard screening series, - Sodium metabisulfite has been recognized for its ability sodium metabisulfite, and potassium several supplemental series, few home products): to cause skin sensitization; other sulfite compounds are metabisulfite) are found extensively among • very strong (+++) reaction to sodium less well understood cosmetic, photography, pharmaceutical, and disulfite/bisulfite (1% in pet) (Fig. 2) - Preliminary studies demonstrate sulfite cross- food industries Reviewing home products, sulfites declared in: reactivity1 • This case demonstrates a novel source of • PalmOlive SoftTouch Almond Milk and Blueberry - Prevalence of sulfite allergy has increased over the sodium disulfite/bisulfite allergy in PalmOlive dish soap (sodium bisulfite) past 20 years2 liquid dish soap • Clairol Professional LiquiColor Gray Busters hair dye (sodium sulfite) New sources of sulfite allergy over the past 5 years3-5 : Case Presentation • rectal enemas Given exclusive • catheter systems • 62-year-old woman with 5- distribution of dermatitis • intravitreal injections year history of bilateral to the hands and hand dermatitis, inconsistency with Conclusion specifically on her palms wearing gloves washing and fingers with dishes (dying her hair she • Sodium bisulfite, a lesser known relative allergen of involvement of the nails exclusively wore gloves), sodium metabisulfite, can be sensitizing and found in her dish soap appeared seemingly inconspicuous sources such as liquid dish • Previous treatments: to be significantly soap • topical steroid ointments contributing to her Figure 2 • coal tar dermatitis References • flurandrenolide tape • Bactine cleansing spray 1. Oliphant T, Mitra A, Wilkinson M. Contact allergy to sodium sulfite and its • Neosporin Treatment and Follow Up relationship to sodium metabisulfite. Contact Dermatitis. 2012;66(3):128-30. • moisturizing creams Figure 1 2. Ralph N, Verma S, Merry S, et al. What Is the Relevance of Contact Allergy - Advised to switch to sulfite-free dish soap to Sodium Metabisulfite and Which Concentration of the Allergen Should • Worked as a caregiver We Use? Dermatitis. 2015;26(4):162-5. - Prescribed twice daily use of triamcinolone 0.1% 3. Borges AS, Val e j o Coelho MM, Fernandes C, et al. Systemic allergic • Affinity for PalmOlive Ultra ointment dermatitis caused by sodium metabisulfite in rectal enemas. Contact SoftTouch Almond Milk Dermatitis. 2018;78(6):429-430. and Blueberry Scent liquid - Follow up (1 week later): symptom improvement 4. Grosch E, Mahler V. Allergic contact dermatitis caused by a catheter system dish soap (Fig. 1) for washing - Repeat Open Application Testing of own Palm Olive containing sodium metabisulfite. Contact Dermatitis. 2017;76(3):186-187. dishes (with inconsistent dish soap: recurrence of hand dermatitis 5. Veramme J, de Zaeytijd J, Lambert J, et al. Contact dermatitis in patients undergoing serial intravitreal injections. Contact Dermatitis. 2016;74(1):18-21. glove use).
Load more

Recommended publications
  • So2 and Wine: a Review
    OIV COLLECTIVE EXPERTISE DOCUMENT SO2 AND WINE: A REVIEW SO2 AND WINE: A REVIEW 1 MARCH 2021 OIV COLLECTIVE EXPERTISE DOCUMENT SO2 AND WINE: A REVIEW WARNING This document has not been submitted to the step procedure for examining resolutions and cannot in any way be treated as an OIV resolution. Only resolutions adopted by the Member States of the OIV have an official character. This document has been drafted in the framework of Expert Group “Food safety” and revised by other OIV Commissions. This document, drafted and developed on the initiative of the OIV, is a collective expert report. © OIV publications, 1st Edition: March 2021 (Paris, France) ISBN 978-2-85038-022-8 OIV - International Organisation of Vine and Wine 35, rue de Monceau F-75008 Paris - France www.oiv.int 2 MARCH 2021 OIV COLLECTIVE EXPERTISE DOCUMENT SO2 AND WINE: A REVIEW SCOPE The group of experts « Food safety » of the OIV has worked extensively on the safety assessment of different compounds found in vitivinicultural products. This document aims to gather more specific information on SO2. This document has been prepared taking into consideration the information provided during the different sessions of the group of experts “Food safety” and information provided by Member States. Finally, this document, drafted and developed on the initiative of the OIV, is a collective expert report. This review is based on the help of scientific literature and technical works available until date of publishing. COORDINATOR OIV - International Organisation of Vine and Wine AUTHORS Dr. Creina Stockley (AU) Dr. Angelika Paschke-Kratzin (DE) Pr.
    [Show full text]
  • Sulfite: Here, There, Everywhere
    Sulfite: Here, There, Everywhere Max T. Baker, PhD Associate Professor Department of Anesthesia University of Iowa Inadvertent Exposures Combustion of fossil fuels, Air pollutant Large quantities as sulfur dioxide are expelled from volcanos Kilauea on the Big Island Small quantities endogenously formed in mammals from sulfur-containing amino acid metabolism Deliberate Exposures As Preservative- Wine, Beer (dates to Roman times From burning sulfur candles) Fruits and Vegetables (reduce browning, extend shelf-life) Pharmaceuticals1 Reductant - Antioxidant - Antimicrobial What are Sulfites? Oxidized Forms of the Sulfur Atom Sulfur Dioxide, MW = 64, bp = - 10oC (gaseous) Sulfur (IV) - Oxidation state of 4 S = Atomic number 16 – electrons/shell, 2,8,6 Sodium Dioxide Readily Hydrates2 Sulfur Carbon Dioxide Dioxide (irritant) H O H2O 2 Sulfurous Unstable Carbonic low acid species acid pH high pH Bisulfite Bicarbonate anion anion Sulfite Carbonate dianion dianion Forms radical Doesn’t form radical Bisulfite Can Combine with SO2 to form Metabisulfite + excess Bisulfite Metabisulfite (disulfite, pyrosulfite) “Sulfite” usually added to drugs as sodium or potassium salts of: Sulfite, Bisulfite, or Metabisulfite Endogenous to Mammals Small quantities formed from sulfur-containing amino acid metabolism - cysteine, methionine3 + - + H2O + 2H + 2 e Sulfite Sulfate Rapidly detoxified by sulfite oxidase (SOX) to form sulfate – a two electron oxidation, molybdenum dependent Two Confirmed Sulfite Toxicities Neurological abnormalities from genetic sulfite oxidase deficiency3 Allergic reactions from exogenous exposure4 Oral, parenteral, inhalational exposure: dermatitis, urticaria, flushing, hypotension, abdominal pain and diarrhea to life- threatening anaphylactic and asthmatic reactions “The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people." - FDA Prevalence – 3-10% are sulfite sensitive among asthmatic subjects.
    [Show full text]
  • Reregistration Eligibility Decision (RED) for Inorganic Sulfites
    Reregistration Eligibility Decision – Inorganic Sulfites May 2007 Reregistration Eligibility Decision Inorganic Sulfites Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency 1801 South Bell Street Arlington, VA 22202 Introduction The Environmental Protection Agency (EPA) has completed its Reregistration Eligibility Decision (RED) for the inorganic sulfites case, which includes the chemicals sulfur dioxide and sodium metabisulfite. This assessment provides information to support the issuance of a Reregistration Eligibility Decision for inorganic sulfites. EPA’s pesticide reregistration process provides for the review of older pesticides (those initially registered prior to November 1984) under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) to ensure that they meet current scientific and regulatory standards. In this document, EPA presents the results of its review of the potential human health effects of dietary, drinking water and occupational/bystander exposure to inorganic sulfites, as well as its ecological risk findings. Evaluations performed by the World Health Organization (WHO), the International Agency for Research on Cancer (IARC), and the Agency for Toxic Substances and Disease Registry (ATSDR) were relied upon for this assessment, in addition to peer-reviewed evaluations performed by the Cosmetic Ingredient Review (CIR), the Organization for Economic Cooperation and Development-Screening Information Data Set (OECD-SIDS) and from other open literature sources. Based on this assessment, the Agency has determined that products containing sulfur dioxide or sodium metabisulfite are eligible for reregistration provided the necessary label changes are made. As a result of this assessment, one tolerance has been reassessed. I. Use Information The inorganic sulfites reregistration case includes the chemicals sulfur dioxide (CAS No.
    [Show full text]
  • Use of SO2 in High-Ph Wines Sulfur Dioxide Dosage
    Purdue extension FS-52-W Commercial Winemaking Production Series Use of SO2 in High-pH Wines Sulfur dioxide dosage By Christian Butzke Wine pH and alcohol destroy the vitamin thiamin, which is essential for the growth of Enology Professor How much free sulfur dioxide (SO2) must a winemaker add or measure to prevent Brettanomyces yeast and certain wine Department of Food Science malolactic fermentation or Brettanomyces bacteria. Only proper concentrations of Purdue University growth if a wine’s pH is 3.95? The answer free SO2 provide additional capacity to bind more products of oxidative aging, [email protected] is between 79 and 112 mg/L, depending on the alcohol content of the wine. The to cleave thiamin, or to kill unwanted SO -sensitive microbes. Brettanomyces requirements for free SO2 concentrations 2 in wine increase exponentially with pH, thrives at higher pH, at temperatures so at pH 4.0 they are 10 times higher greater than 55˚F, in larger ullages, and than at pH 3.0. This does not leave room at residual yeast nutrient levels. Luckily for rule-of-thumb or routine sulfite the thiamin break-up — given proper additions/adjustments. Sulfites added amounts of free bisulfite — occurs faster at a higher pH. Ethanol acts synergistically to wine in the form of either SO2 gas or potassium metabisulfite salt exist and enhances the bacteria-killing effect essentially in two forms: ionized bisulfite of molecular SO2, so high-alcohol wines require less SO protection (see dosage (free SO2) and sulfur dioxide gas 2 charts based on wine alcohol content (molecular SO2).
    [Show full text]
  • Safety Assessment of Sulfites As Used in Cosmetics
    Safety Assessment of Sulfites as Used in Cosmetics Status: Re-Review for Panel Consideration Release Date: August 22, 2019 Panel Meeting Date: September 16-17, 2019 The 2019 Cosmetic Ingredient Review Expert Panel members are: Chair, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V. Belsito, M.D.; Curtis D. Klaassen, Ph.D.; Daniel C. Liebler, Ph.D.; James G. Marks, Jr., M.D., Ronald C. Shank, Ph.D.; Thomas J. Slaga, Ph.D.; and Paul W. Snyder, D.V.M., Ph.D. The CIR Executive Director is Bart Heldreth, Ph.D. This safety assessment was prepared by Wilbur Johnson, Jr., Senior Scientific Analyst © Cosmetic Ingredient Review 1620 L Street, NW, Suite 1200 ♢ Washington, DC 20036-4702 ♢ ph 202.331.0651 ♢ fax 202.331.0088 ♢ [email protected] Distributed for Comment Only -- Do Not Cite or Quote Commitment & Credibility since 1976 Memorandum To: CIR Expert Panel Members and Liaisons From: Wilbur Johnson, Jr. Senior Scientific Analyst Date: August 22, 2019 Subject: Re-Review of the Safety Assessment of Sulfites The CIR Expert Panel first reviewed the safety of Sulfites in 2003. The Panel concluded that Ammonium Bisulfite, Ammonium Sulfite, Potassium Metabisulfite, Potassium Sulfite, Sodium Bisulfite, Sodium Metabisulfite, and Sodium Sulfite are safe as used in cosmetic formulations. The original report is included for your use (identified as sulfit092019orig in the pdf). Minutes from the deliberations of the original review are also included (sulfit092019min_orig). Because it has been at least 15 years since the safety assessment was published, in accordance with CIR Procedures, the Panel should consider whether the safety assessment of Sulfites should be reopened.
    [Show full text]
  • Ammonium Hydrogen Sulfite Water As an Authorized Food Additive and Establish Compositional Specifications and Use Standards for This Additive
    Amendment to the Ordinance for Enforcement of the Food Sanitation Act and the Specifications and Standards for Foods, Food Additives, Etc. The government of Japan will designate ammonium hydrogen sulfite water as an authorized food additive and establish compositional specifications and use standards for this additive. Background Japan prohibits the sale of food additives that are not designated by the Minister of Health, Labour and Welfare (hereinafter referred to as “the Minister”) under Article 12 of the Food Sanitation Act (Act No. 233 of 1947; hereinafter referred to as “the Act”). In addition, when specifications or standards for food additives are stipulated in the Specifications and Standards for Foods, Food Additives, Etc. (Public Notice of the Ministry of Health and Welfare No. 370, 1959), Japan prohibits the sale of those additives unless they meet the specifications or the standards pursuant to Article 13 of the Act. In response to a request from the Minister, the Committee on Food Additives of the Food Sanitation Council under the Pharmaceutical Affairs and Food Sanitation Council (hereinafter referred to as “the Committee”) has discussed the adequacy of the designation of ammonium hydrogen sulfite water as a food additive. The conclusion of the Committee is outlined below. Outline of conclusion The Minister should designate ammonium hydrogen sulfite water as a food additive unlikely to cause harm to human health pursuant to Article 12 of the Act and should establish compositional specifications and use standards for this additive pursuant to Article 13 of the Act (see Attachment for the details). Attachment Ammonium Hydrogen Sulfite Water 亜硫酸水素アンモニウム水 Standards for Use (draft) Permitted for use in grape juice used for wine production and grape wine only.
    [Show full text]
  • INTERNATIONAL ŒNOLOGICAL CODEX Ammonium Hydrogen
    INTERNATIONAL ŒNOLOGICAL CODEX Ammonium Hydrogen Sulfite COEI-1-AMMHYD: 2007 AMMONIUM HYDROGEN SULFITE Ammonium bisulfite NH4HSO3 = 99.07 (Oeno 14/2000 modified by Oeno 3/2007) 1. OBJECTIVE, ORIGIN AND SCOPE OF APPLICATION This product falls in the category of preservatives and is used exclusively for fermentation operations. It makes available sulfur dioxide and ammonium ions, which can be directly assimilated by the yeast. There are regulatory restrictions on the amount of ammonium that can be added and on sulfur dioxide content. 2. LABELING The concentration of this product, as well as the safety and storage conditions, should be indicated on the label. 3. CENTESIMAL COMPOSITION NH3 17.16 SO2 64.67 4. PROPERTIES Ammonium hydrogen sulfite always takes an aqueous solution form. This solution emits a piquant sulfur dioxide odor. 5. SOLUBILITY Water at 60 °C 847 g/l Alcohol, 95% by vol. Slightly soluble 6. IDENTIFYING CHARACTERISTICS Aqueous solutions of ammonium hydrogen sulfite produce reactions of ammonium (release of ammonia in the presence of sodium hydroxide when heated) and sulfur dioxide (filter paper soaked in potassium iodate and starch turns blue). E-COEI-1-AMMHYD 1 INTERNATIONAL ŒNOLOGICAL CODEX Ammonium Hydrogen Sulfite COEI-1-AMMHYD: 2007 TESTS 7.1. Sulfur Ash As quantified as indicated in the Annex, the proportion of ammonium hydrogen sulfite ash should not be greater than 0.2 per 100. 7.2. Preparing the Solution for Tests Prepare a 10 pp 100 (m/v) solution. 7.3. Iron To 5 ml of the solution prepared for testing under paragraph 2, add 1 ml of concentrated hydrochloric acid (R), one drop of 2 pp 100 potassium permanganate (R) and 2 ml of 5 pp 100 potassium thiocyanate (R).
    [Show full text]
  • Chapter 19: Undeclared Major Food Allergens and Food Intolerance Substances
    CHAPTER 19: UNDECLARED MAJOR FOOD ALLERGENS AND FOOD INTOLERANCE SUBSTANCES This guidance represents the Food and Drug Administration’s (FDA’s) current thinking on this topic. It does not create or confer any rights for or on any person and does not operate to bind FDA or the public. You can use an alternative approach if the approach satisfies the requirements of the applicable statutes and regulations. If you want to discuss an alternative approach, contact the FDA staff responsible for implementing this guidance. If you cannot identify the appropriate FDA staff, call the telephone number listed on the title page of this guidance. UNDERSTAND THE POTENTIAL HAZARD • Food Allergens Food allergies are a significant public health No minimum threshold has been established for concern. Allergic reactions vary in severity from allergenic ingredients, for either intentionally or gastrointestinal disturbances and skin irritation, unintentionally added allergens. However, there are to anaphylaxis, shock and death. Consumers with emerging data on levels of major food allergens that allergies must avoid food containing allergenic may be tolerated by a large majority of individuals materials to avoid these reactions. Because of in the allergic population and that can be used in this, consumers rely on food labels to disclose manufacturer’s risk assessment of allergen cross- the presence of allergenic ingredients. Successful contact hazards. avoidance requires that food manufacturers de- velop, implement, and maintain the necessary • Labeling: controls to ensure allergens that are intended to be present in a food are declared on the label and that The Food Allergen Labeling and Consumer Protection the presence of unintended allergens is prevented.
    [Show full text]
  • Sethness Products Company
    SETHNESS PRODUCTS COMPANY SULFITE IN SETHNESS CARAMEL COLORS Sethness Caramel Colors are 100% Caramel Color. Sethness Caramel Colors do not contain any post manufacturing "sulfiting agents" typically added to food products as oxygen scavengers. These sulfiting agents are used to enhance the stability of the final product. Sulfiting agents used for stabilization are readily determined by both digestive and non- digestive methods. Sethness Caramel Colors do not contain any stabilizing sulfites. The sulfite found in Sethness Caramel Colors comes from one of two sources: 1. When Caramel Color is tested to contain above 50 ppm of sulfite, then sulfite is used as a necessary and allowed process reactant (as defined by 21 CFR 73.85) to assist in the formation of the color bodies generated in the process of manufacturing Caramel Colors. These are Class II (E150b) and Class IV (E150d) Caramel Colors. This sulfite is incorporated into the Caramel Color as a part of the polymer chains. When a Sethness Caramel Color is analyzed for free sulfite using a non-digestive method, the result is nil. 2. When Caramel Color is tested to contain less than 50 ppm of sulfite, then t h e sulfite result is assumed to be from residual levels in the carbohydrate source. Also, the test for sulfite is such that it will not give a result that is conclusively free of sulfites. Therefore, we have set our sulfite limits to be within the limit of detection and accuracy of the test and possible residual sulfites from the carbohydrate source. These are Class I (E150a) and Class III (E150c) Caramel Colors.
    [Show full text]
  • Sulfur Dioxide and Some Sulfites, Bisulfites and Metabisulfites
    SULFUR DIOXIDE AND SOME SULFITES, BISULFITES AND METABISULFITES 1. Exposure Data 1.1 Chemical and physical data 1.1.1 Synonyms and structural and molecular data Sulfr dioxi Chem. Abstr. Serv Reg. No.: 7446-09-5 Replaced CAS Nos.: 8014-94-6; 12396-99-5; 83008-56-4; 89125-89-3 Chem. Abstr. Name; Sulfur dioxide IUPAC Systematic Name: Sulfur dioxide Synonyms: Sulfurous acid anhydride; sulfurous anhydride; sulfurous oxide; sulfur oxide (S02); sulfur superoxide; sulphur dioxide 0=8=0 S02 MoL. wt: 64.07 Sodium sulfte Chem. Abstr. Serv Reg. No.: 7757-83-7 Altemate CAS No.: 10579-83-6 Replaced CAS No.: 68135-69-3 Chem. Abstr. Name: Sulfurous acid, di sodium salt IUPAC Systematic Name: Sulfurous acid, disodium salt Synonyms: Anhydrous sodium sulfite; disodium sulfite; sodium sulphite o 1/ Na · 0 - 8 - 0 · Na Na2S0J MoL. wt: 126.04 Sodium bisulfe Chem. Abstr. Serv Reg. No.: 7631-90-5 Replaced CAS Nos.: 57414-01-4; 69098-86-8; 89830-27-3; 91829-63-9 Chem. Abstr. Name: Sulfurous acid, monosodium salt IUPAC Systematic Name: Sulfurous acid, monosodium salt -131- 132 lARe MONOGRAPHS VOLUME 54 Synonyms: Hydrogen sulfite sodium; monosodium sulfite; sodium acid sulfite; sodium bisulphite; sodium hydrogen sulfite; sodium sulfite (NaHS03) o Il HO - S - a · Na NaHS03 MoL. wt: 104.06 Sodium metabisulfte Chem. Abstr. Serv Reg. No.: 7681-57-4 Altemate CAS No.: 7757-74-6 Replaced CAS No.: 15771-29-6 Chem. Abstr. Name: Disulfurous acid, disodium salt IUPAC Systematic Name: Pyrosulfurous acid, disodium salt Synonyms: Disodium disulfite; disodium metabisulfite; disodium pyrosulfite; sodium disulfite; sodium metabisulphite; sodium pyrosulfite oIl Il0 Na · 0- S - a - S - a · Na .Na2S20S MoL.
    [Show full text]
  • An Abstract of the Thesis Of
    AN ABSTRACT OF THE THESIS OF María del Pilar Alessandri for the degree of Master of Science in Food Science and Technology presented on September 25, 2018. Title: Nutritional and Genetic Aspects of Sulfite Excretion During Fermentation by Wine Strains of Saccharomyces cerevisiae Abstract approved: ______________________________________________________ Alan T. Bakalinsky Reductive sulfate assimilation, the biological process by which sulfur- containing amino acids and key derivatives are synthesized from sulfate, is broadly shared among bacteria, fungi, and plants. It is the major, if not sole source of methionine and cysteine for Saccharomyces cerevisiae during wine fermentation. Two obligate intermediates formed in the process, sulfite and hydrogen sulfide, are important in winemaking because both compounds can be excreted during fermentation and influence wine quality. Hydrogen sulfide is highly undesirable if it exceeds threshold concentrations and is not reabsorbed by the yeast or lost by evaporation. Winemakers commonly add and monitor levels of sulfite for use as a mild antioxidant and antimicrobial agent because most wine yeasts do not excrete more than 10-30 mg/L. However, too much sulfite, whether excreted or added, can inhibit the Oenococcus oeni-mediated malolactic fermentation (MLF) that typically follows the alcoholic fermentation in the production of red and some white wines. Deliberate exploitation of the natural ability of yeast to excrete high amounts of sulfite could potentially replace the need for additions made by winemakers for the production of white wines that are neither aged nor undergo the MLF. This is relevant to organic winemaking because unlike the sulfite additions that are disallowed by current USDA regulations, sulfite produced by yeast is permissible.
    [Show full text]
  • Coei-1-Potanh: 2000
    INTERNATIONAL ŒNOLOGICAL CODEX Potassium Anhydrous Sulfite COEI-1-POTANH: 2000 POTASSIUM ANHYDROUS SULFITE Potassium pyrosulfite Potassium disulfite Potassium metabisulfite Kalii metabisulfis K2S2O5 = 222.3 SIN No. 224 (Oeno 34/2000) 1. OBJECTIVE, ORIGIN AND SCOPE OF APPLICATION Potassium anhydrous sulfite, commonly called potassium metabisulfite, is used because of the sulfur dioxide it makes available. Potassium metabisulfite, which is sold in powdered form, contains 52- 55% by weight SO2. There are regulatory limits restricting the sulfur dioxide content of wines. 2. LABELING The label should indicate the product's purity as well as its safety and storage conditions. 3. CENTESIMAL COMPOSITION Sulfur dioxide 57.63 Potassium 35.17 4. SOLUBILITY Water at 20 °C 454.5 g/l Alcohol, 95% by vol. insoluble 5. IDENTIFYING PROPERTIES 5.1. 5 ml of aqueous 10 pp 100 (m/v) solution treated with 5 ml of 1/10 diluted sulfuric acid (R) releases sulfur dioxide and reduces iodine and potassium permanganate. 5.2. The 10 pp 100 (m/v) aqueous solution is acidic as indicated by methyl red (R) of (pHapproximately 5). E-COEI-1-POTANH 1 INTERNATIONAL ŒNOLOGICAL CODEX Potassium Anhydrous Sulfite COEI-1-POTANH: 2000 5.3. The 1 pp 100 (m/v) aqueous solution produces potassium- based reactions. 6. TESTS 6.1. Preparing the Test Solution in a Concentration of 10 pp 100 Prepare a solution in a concentration of 10 pp 1000 (m/v). 6.2. Preparing a Test Solution in a Concentration of 1 pp 100 Prepare a 1 pp 100 (m/v) solution by diluting the previous solution (6.1) to 1/10.
    [Show full text]