Vital Signs SUMMER 2015 | VOLUME 67

FEATURE STORIES Breast Cancer Page 4 Liver Damage Page 6 Q&A: New Leadership Page 8 Community Calendar Page 12

Shortage of Organs for Transplantation Requires that More Donors Step Forward Organ donation has been described as one of medicine’s greatest modern miracles — in many cases resulting in a long and healthy life for individuals who were near death. Each day in the United States, an average of 79 people receive life-saving transplants, according to federal statistics, but 21 others die while waiting for transplants that can’t take place because of the shortage of donated organs.

Continued on page 7 Vital Signs SUMMER 2015 | VOLUME 67

UCLA Baby App The new UCLA Baby app lets a woman keep track of everything during her pregnancy, from counting kicks to tracking weight and timing contractions. After entering the baby’s due date, the app will In This Issue provide tips, weekly milestones, to-do checklists and introductions to the UCLA care team, as well What’s New at UCLA as recommend tests and guides to classes, online 2 support groups and breastfeeding information. In Your Community The app is available for both the iPhone and Android. 3  UCLA offers services and support near you. For more information, go to: Breast Cancer uclahealth.org/babyapp 4  New therapies improve outlook for women with advanced breast cancer.

Liver Damage 6 Overuse of some nonprescription pain relievers and nutritional supplements Online Access 24/7 causes potential harm to liver. With myUCLAhealth, UCLA Health’s 7 Organ Transplant online patient portal, patients can request For organ transplantation to truly be appointments, view their medical history and successful, potential donors need to most test results, request prescription refills indicate their willingness to give. and communicate electronically with their Q&A: UCLA Health Leadership medical team. Patients may also designate a 8  Dr. John Mazziotta assumes new surrogate, such as an adult or child, to access roles as CEO of UCLA Health and their account. If you haven’t already signed up dean of the David Geffen School of Medicine at UCLA. for myUCLAhealth, you will receive an access code during your next doctor’s or hospital Children with Facial Deformities visit. Help with setting up myUCLAhealth 10 Coordinated care among different account is available 24/7; call (855) 364-7052. specialties is essential to achieve the best outcomes. For more information, go to: uclahealth.org/myuclahealth Caffeine and Exercise 11 Moderate coffee consumption can help to propel your workout and increase weight loss.

Community Calendar 1 2 Health and wellness for the community. Get the Care You Need, Right Away UCLA Health now offers same-day appointments, in 27 specialties, Monday through Friday. In most cases, depending on the level of care you need and the time of day when you call, you’ll be seen by a physician that day. Calls before noon will be offered same-day appointments; calls after noon will be offered next-day appointments. To make a same-day appointment, call 1-800-UCLA-MD1

For more information, go to: uclahealth.org/sameday

UCLAHEALTH.ORG 1-800-UCLA-MD1 (1-800-825-2631) HEAD AND NECK

Head and Neck Office Opens in Santa Monica

The new office combines state-of-the-art technology, world-class expertise and research-supported patient care with the convenience associated with community offices.

UCLA physicians see patients of all ages “Patients are able to see the same faculty and with all types of disorders of the head members who practice in Westwood, but and neck. These conditions involve a wide with the convenience of being closer.” range of concerns — from ear and sinus The office, which includes pediatric infections to associated hearing problems, otolaryngologist Alisha West, MD, and UCLA Head and Neck tonsil-related disorders, problems involving otolaryngologist Paul Kedeshian, MD, is in Santa Monica snoring, and thyroid disease. The medical part of the UCLA Head and Neck Cancer team also treats trauma to the facial bones Program, which provides comprehensive, 1131 Wilshire Blvd., Suite 302 and voice disorders. Head and neck cancers personalized care for benign and malignant Santa Monica, CA 90401 are also evaluated and treated. tumors of the head and neck. The head and Mon – Fri, 8 am – 5 pm In addition to office visits at the new facility, neck consultation clinic in Westwood sees head and neck physicians perform most more than 50,000 patient visits each year. (424) 259-6559 procedures at the nearby UCLA outpatient The UCLA Voice Center for Medicine and surgery center. Same-day appointments are the Arts, also in Westwood, sees patients UCLA Head and Neck available for patients who need them. with voice problems ranging from benign disorders, such as vocal nodules, polyps “This office offers the best of both worlds in Westwood and papillomas, to more complex disorders, for the Santa Monica community,” such as spasmodic dysphonia, airway Peter Morton Medical Building says Eddie Ramirez, MD, FACS, an stenosis and laryngeal cancer. otolaryngologist who sees children and 200 UCLA Medical Plaza, Suite 550 adults with conditions of the head and neck. Los Angeles, CA 90095 Mon – Fri, 7:30 am – 5:30 pm (310) 206-6688

UCLA Voice Center for Medicine and the Arts 924 Westwood Blvd., No. 515 Los Angeles, CA 90024 Mon – Fri, 8:30 am – 5:30 pm (310) 794-8634

Eddie Ramirez, MD, FACS

Vital Signs Summer 2015 Vol. 67 3 ONCOLOGY

New Treatment Option for Women with Advanced Breast Cancer

omen diagnosed with one of the Comprehensive Cancer Center. “For many Wmost common types of breast cancer years, people have been trying to target these now have an additional medication to help CDK4/6 receptors. What we have been able fight the disease. The U.S. Food and Drug to do is identify a type of cancer that might Administration (FDA) recently approved benefit from CDK4/6 inhibition.” palbociclib (Ibrance) for postmenopausal Palbociclib is used in combination with patients with breast cancer that has spread letrozole, a medication used to treat this to other areas of the body. type of breast cancer in postmenopausal The medication is aimed at women with a women. In the clinical trial, participants type of breast cancer known as estrogen treated with palbociclib plus letrozole lived receptor-positive/HER2-negative (ER+/ about 20 months without their disease HER2-). The ER+/HER2- subgroup progressing, compared to about 10 months represents about 60 percent of breast-cancer in participants receiving only letrozole. More cases, “so we believe this agent can have a than 80 percent of the patients in the study great impact,” says Dennis Slamon, MD, PhD, received some benefit from this treatment. director of the Revlon/UCLA Women’s In April 2013, the FDA granted the drug Cancer Research Program and Clinical/ “breakthrough therapy” status, allowing it Translational Research at UCLA’s Jonsson to be fast-tracked to early approval. Comprehensive Cancer Center. “I believe palbociclib will now become The medication represents a new strategy in a standard treatment approach for treating breast cancer. It’s the first in a class postmenopausal women with ER+/HER2- of medications that target proteins called metastatic breast cancer,” Dr. Slamon says. cyclin-dependent kinases 4 and 6 (CDK4/6). The drug did cause a decrease in infection- These proteins allow cancer cells to divide, fighting white blood cells. But that side effect but palbociclib disrupts them. Researchers is manageable, Dr. Finn says. “So much have known about these proteins for many cancer research is just hit and miss. You do years, but it was unclear who might be helped a study and hope to get something,” he says. by drugs that disrupted the proteins. In “This clinical study was based on a very studies that began in 2007, UCLA scientists strong scientific rationale. It wasn’t random. demonstrated that women with estrogen That is why we saw positive results. This type receptor-positive breast cancer could benefit of result is not often seen in cancer medicine.” from drugs that addressed CDK4/6. CDK4/6 medications are under investigation “Cell division is not well controlled; that’s for other types of cancers, Dr. Finn says. one of the hallmarks of cancer,” says Richard Finn, MD, of UCLA’s Jonsson To view a video about treatment options for women with breast cancer, go to: uclahealth.org/treatmentoptions

UCLAHEALTH.ORG 1-800-UCLA-MD1 (1-800-825-2631) Breast Cancer Myth & Fact

“If I find a lump in my breast,  I have cancer.” 80% of lumps in women’s breasts are caused by benign changes, cysts or other conditions.

“I’m too young to get  breast cancer.”

25% of women with breast cancer are younger than 50 years old.

“Only women with a family  history of breast cancer  are at risk.”

 80% of women diagnosed with breast cancer have no identifiable risk factors for the disease.

“Men can’t get breast cancer.”

Approximately 1,700 men will be diagnosed annually with breast cancer and 450 will die.

“ This clinical study was based on a very strong “A mammogram can cause breast cancer to spread.” scientific rationale. It wasn’t random. That is Radiation doses are regulated by why we saw positive results. This type of result the FDA and are low — equivalent is not often seen in cancer medicine.” of the amount the average person receives from their surrounding environment over three months.

Vital Signs Summer 2015 Vol. 67 5 GASTROENTEROLOGY

Nonprescription Supplements and Pain Relievers Contribute to Liver Damage The overuse of nutritional supplements and nonprescription pain relievers like acetaminophen is contributing to a growing incidence of serious liver damage caused by these chemical agents, a condition known as hepatotoxicity.

“A patient has a medical or dental procedure increased fivefold in the last decade. “We’re and afterward has a lot of pain, so he or she now starting to see the effects,” he says. starts taking large numbers of acetaminophen The most common supplement-induced and develops toxicity that is potentially liver injuries result from workout or fatal without a liver transplant,” says UCLA bodybuilding supplements, with weight-loss gastroenterologist Francisco Durazo, MD. supplements not far behind. Less common but still important to be aware of, he adds, Nutritional supplements are cause for similar are injuries from consuming large quantities concern. More than half of Americans of popular energy drinks. take supplements, Dr. Durazo notes, and consumption of herbal medications has It is important that patients talk with their physicians about any nonprescription products they are taking, and for physicians to offer counsel on the potential dangers of misuse, Dr. Durazo says. In the case of acetaminophen, patients also need to be aware that it can be present in other medications, from analgesics to cold remedies. Dr. Durazo cautions that certain factors can predispose someone to increased acetaminophen toxicity, including heavy alcohol use, fasting and medications that speed up the metabolism. When it comes to nutritional supplements — be they workout-enhancing supplements, weight-loss pills or energy-boosting drinks — the problem is compounded by misleading advertising and labeling, contends Fady M. Kaldas, MD, director of the liver-transplant service at the Dumont- UCLA Transplant Center. “There is a big market for people who want to move away from Western medicine and buy something

UCLAHEALTH.ORG 1-800-UCLA-MD1 (1-800-825-2631) TRANSPLANT

Continued from cover Shortage of Organs for Transplantation Requires that More Donors Step Forward

To help address this shortage, it is also be performed using living donors — important for individuals to indicate their particularly involving the kidney. At willingness to be an organ donor upon UCLA, nearly half of all kidney transplants their death, says Gabriel Danovitch, MD, are from living donors. “In people who medical director of UCLA’s Kidney and have passed a careful series of tests and Pancreas Transplant Program. “It reduces evaluations, it is perfectly safe to have the stress on surviving family members one kidney removed, and these living during that time of decision if they donors can go on to lead a full, active and know what their loved one wanted,” unrestricted life,” Dr. Danovitch says. “It Dr. Danovitch says. “And the knowledge can be extremely gratifying not just for the that some good may come out of the recipients, but for donors who experience situation can provide some solace the blessing of seeing someone they care during this time of loss.” about get their health back. We all know it’s often even more satisfying to give the that’s herbal or ‘natural,’” Dr. Kaldas says. Dr. Danovitch says there continue to be perfect gift than to get the perfect gift.” “A lot of people think that it has to be good misconceptions around organ donation, for them if it’s natural.” although he believes they are less widely Although living donors are usually close held than in the past. One is that less of an relatives, increasingly transplants are However, the supplement industry is not effort will be made to save the lives of those performed involving friends, distant regulated by the U.S. Food and Drug who have signed an organ-donor card. relatives and strangers or anonymous Administration, and products typically “That is absolutely not true,” Dr. Danovitch donors, particularly as issues of don’t need to show evidence of safety or says. “The medical team’s job is to keep compatibility are more easily overcome. efficacy to be sold. There have been cases you alive, and that is separate from those UCLA’s kidney transplant program has in which popular weight-loss supplements whose job it is to fulfill the family’s wishes been among the most active in the country have been removed from the market after after death.” There are well-defined criteria in carrying out kidney exchanges, which reports of adverse events but return as for determining death, he adds, and organ increase the donor pool by matching rebranded products with similar ingredients. donation cannot occur until those criteria patients who have an incompatible Patients with hepatotoxicity from supplements have been met. donor with other incompatible donor- recipient pairs. typically experience nausea, vomiting, Some people also hold the mistaken belief abdominal pain and fatigue, along with that society’s most privileged members elevated liver-function tests, UCLA surgeon will be more likely to receive their organs, Keri E. Lunsford, MD, PhD, explains. but Dr. Danovitch, who has been active Patients may assume their physician wants nationally on organ-allocation issues, says to know only about the prescription that there are strict criteria in this regard medications they are taking and neglect as well, and the process is designed to be to volunteer that they also are taking blind to socioeconomics or race. “For supplements, Dr. Lunsford says. And organ donation to be successful many doctors don’t ask, “assuming that a in any society, there needs to be supplement is like a multivitamin and not a trusting relationship between a big deal.” She advises that patients tell the medical community involved their physicians about the use of any in transplantation and the public supplements, even if the doctor doesn’t ask. at large, and we have shown ourselves to be trustworthy, as illustrated by the rising authorization rates,” he says. Although most organs come from deceased donors, transplantation can

Vital Signs Summer 2015 Vol. 67 7 Dr. John Mazziotta Assumes Leadership of UCLA Health

John Mazziotta, MD, PhD, is the new CEO of UCLA Health and dean of the David Geffen School of Medicine at UCLA. A neurologist, he is the founder of UCLA’s Ahmanson-Lovelace Brain Mapping Center and former chair of the Department of Neurology. His perspective after some 30 years at UCLA gives D r. Mazziotta a clear view of the institution and the direction in which he would like to lead.

UCLAHEALTH.ORG 1-800-UCLA-MD1 (1-800-825-2631) INTERVIEW

What are the opportunities that lie ahead? for the patient surrounds him or her in a of examples of the incredible work that is cost-effective way. No one has done this in being done at UCLA, the kind of work we When there is a significant change in academic medicine. The first one to do it will want to support and advance even further. leadership, there is the opportunity to be the role model for the rest of the country, examine the governance and structure of Your office is in the Center for the perhaps for the rest of the world. I want the organization. It is like starting with Health Sciences building, on the UCLA UCLA to be that role model. In the areas of a clean slate and makes it possible to ask campus, which is undergoing a significant research, we have identified six themes in questions such as, “How do we change the transformation. What is happening here? which we want to particularly invest and structure to become more effective, efficient excel: cancer; immunology; cardiovascular This has been the single-largest renovation and responsive?” It is good to have a chance medicine; neuroscience; metabolism; and project in the history of the University of to engage in self-examination. Today’s degeneration, regeneration and repair. California, to transform this building into a healthcare environment is undergoing space for high-intensity research laboratories. dramatic change, and we need to be prepared What are some examples of how we The building has been seismically retrofitted, to adapt to that without changing the beliefs already excel in the research areas you and now it is being reassembled into clean, that are embedded in our core mission. have identified? open spaces with a all-new infrastructure. What are your priorities as you take on There are many, but let’s highlight one: There will be a floor devoted to each of the your new roles? cancer. Within this past year, three new six research themes that I mentioned. Other cancer therapies developed at UCLA have areas will be used to facilitate different kinds We should strive to be the best in the world been approved by the U.S. Food and Drug of public-private partnerships. We will at the things we choose to do. We can’t be Administration. These therapies are the partner with established organizations and the best in the world at everything, but, results of years of investigation led by businesses in the private sector to do joint when we pick a subset of those things, we UCLA researchers, and they offer new research projects, possibly startup companies. should pick the ones in which we can be alternatives for patients with such cancers as As a university, we’re not a bottom-line the very best. It means taking the steps to melanoma, non-small-cell lung cancer and organization that focuses only on the money make UCLA the role model nationally for estrogen-receptor-positive breast cancer. that can be made from these opportunities. enabling an academic medical center to I will highlight one other. In the area of Rather, we will pursue intellectual property truly deliver patient-centered and integrated cardiovascular research, our scientists have that can lead to societal benefit, even if it isn’t care. Instead of being compartmentalized developed an entirely novel therapeutic necessarily a financial winner. That’s going to into the “department of the eyeball” and approach to fighting vascular plaques — a be a very exciting activity. the “department of the nervous system,” synthetic protein that is designed to mimic where the patient must go from one center HDL, or “good cholesterol.” This therapy was to another to receive care, we want to brought to clinical trial, which resulted in a create a system where whatever is needed licensing agreement. These are just a couple

John Mazziotta, MD

Vital Signs Summer 2015 Vol. 67 9 PEDIATRICS

Coordinated Care Improves Outlook for Children with Facial Deformities For children born with facial abnormalities, treatment often involves multiple surgeries and other consultations from a wide variety of medical and dental specialists, in some cases stretching from infancy to early adulthood. For these young patients and their families, the coordinated effort of a team of experts is essential for both convenience and optimal care, says Wayne Ozaki, MD, DDS, a pediatric plastic surgeon and director of UCLA Craniofacial Surgery.

“Most of these patients need more than just The team meets regularly to discuss cases, a single operation from a plastic surgeon,” and patients and their families typically are Dr. Ozaki says. “If they are going to many able to have all of their consultation needs different specialists who aren’t working met in a single day. The clinic is one of the together, they’re getting disjointed care.” largest of its kind in the United States, and has pioneered new treatments to improve The UCLA Craniofacial Clinic team includes outcomes for the most challenging patients. experts from more than a dozen specialties, including pediatrics, plastic surgery, oral Approximately 200,000 children are born surgery, orthodontics, pediatric dentistry, each year with facial deformities. The most neurosurgery, ophthalmology, head and neck common is cleft lip or palate, which occurs surgery, audiology, maxillofacial prosthetics, when the baby’s lip or mouth fails to form speech pathology, social work and genetics. properly during gestation. Other congenital

UCLAHEALTH.ORG 1-800-UCLA-MD1 (1-800-825-2631) EXERCISE

abnormalities seen by the UCLA Craniofacial Clinic include craniosynostosis (an abnormal A Cup of Joe for More Get Up and Go head shape resulting from the premature fusion of two or more bones of the skull) and Everyone knows that the prescription for weight loss relies heavily on craniofacial microsomia (abnormalities of proper diet and exercise, but could an optimal and well-timed dose of facial symmetry, including misshapen ears and jaws). Beyond congenital conditions, the caffeine confer an additional benefit? “There has been a great deal of clinic’s doctors treat pediatric patients with interest in the effects of caffeine on exercise and weight loss, and for trauma-related injuries, such as those from the most part it appears that in moderation, caffeine can contribute in a car accidents, faces disfigured from cancer treatment, and vascular malformations. positive way,” says Daniel Vigil, MD, a UCLA sports-medicine physician. In most cases, Dr. Ozaki notes, these The latest evidence comes from a recent and thus more enjoyable, it might increase deformities are not merely cosmetic concerns. study finding that among athletes, the frequency of workouts — another “There are functional issues as well,” he says. exercising after consuming a moderate potential benefit. “Kids with clefts of the lip and palate can’t amount of coffee resulted in their burning eat very well, and hearing and speech can be One of the concerns some people have 15 percent more calories for three hours affected. For a child with craniosynostosis, about caffeine prior to exercise is that post-workout than non-coffee drinkers. the head can’t grow in a normal way, and it will make them dehydrated. “We Dr. Vigil explains that the positive effect there are increased pressures on the brain, now know that caffeine doesn’t cause relates to faster and deeper breathing in along with the abnormal head shape.” dehydration, especially if you start out the hours following the exercise, which well hydrated,” Dr. Hove says. Treatment often is a multistage process that results in more calories burned. He notes includes surgeries at various developmental that other studies have found that caffeine Dr. Vigil warns against taking the milestones, as well as rehabilitative services. can promote the preferential burning of fat evidence too far. The optimal intake For example, Dr. Ozaki explains, a newborn over carbohydrates, which could also be of coffee for an average-weight person with a cleft lip and palate may have a surgical beneficial to weight-loss efforts. seeking to achieve the exercise-related lip repair at 3 months, a palate repair at benefit is about two-to-three cups roughly Jason Hove, MD, a UCLA family medicine 10-to-12 months, nose-lip revision surgery at one-to-two hours before the workout. physician with an expertise in exercise age 5, a bone graft at age 8 to use bone from “Someone who is already drinking four physiology, points out that one well- his or her hip to repair the cleft in their gums, or five cups a day isn’t likely to get a known benefit of consuming caffeine and then surgeries to fix the misshapen nose benefit from drinking more,” he notes. prior to exercise is its ability to boost and jaw as the child gets older. Because of the Similarly, people who aren’t coffee endurance. “What it comes down to is complexity of these and other cases seen at drinkers shouldn’t feel the need to start, perceived exertion — how hard you think the clinic, patients typically are seen at least since the benefits are only marginal. you’re working,” Dr. Hove says. “There is annually until age 21. some evidence that caffeine makes it easier “We need to keep in mind that diet makes “At different stages, these patients may need for people to exercise longer and harder, up about 80 percent of the weight-loss to see different experts,” Dr. Ozaki says. which is going to burn more calories.” equation,” Dr. Hove says. “Of course, “By having everyone here and working Dr. Hove adds that if the caffeine makes exercise is certainly important for fitness together, we can better meet our goal of the physical activity seem less grueling as well as for losing weight, and if caffeine giving every child a chance to feel normal can be used to enhance that effect, that is and good about themselves.” going to be beneficial.”

To view a video For more information about coffee and about the UCLA Pediatric exercise, go to: Craniofacial Program, uclahealth.org/ go to: uclahealth.org/ coffeeandexercise pediatriccraniofacial

Vital Signs Summer 2015 Vol. 67 11 Community Health Programs

JULY, AUGUST, SEPTEMBER 2015 COMMUNITY HEALTH PROGRAMS UCLA Health offers community programs and events to help our neighbors lead healthier lives through wellness education and the prevention of illness and injury. Scan the QR code on the left with your smartphone or go to uclahealth.org/calendar for more information.

AGING AND MEMORY CARE ASTHMA CANCER

Brain Boot Camp Asthma Update Colorectal Cancer: Recent Advances in This intensive course teaches healthy lifestyles Gerard Frank, MD, UCLA pulmonologist, will Detection and Treatment and enhances memory ability for people with discuss the differences between allergic and Zev Wainberg, MD, UCLA GI Oncology program, age-related memory concerns. nonallergic asthma and how to treat them. will discuss care of colorectal cancer patients When: Sessions scheduled on individual basis When: Thursday, August 6 / Noon – 1:30 pm from initial diagnosis through treatment of early Where: UCLA Longevity Center, Where: OASIS, Macy’s 3rd Level, 10730 W Pico Bl disease, management of metastatic cancer, traditional treatments (chemotherapy and 10945 Le Conte Ave, Ste 3119 RSVP: (800) 516-5323 biological therapy) and targeted biological agents Info: (310) 794-4055 being tested in clinical trials and emerging in Cost: $300 for 3 hours BRAIN ANEURYSM the clinic. Memory Care When: Tuesday, July 14 / 7 – 9 pm Brain Aneurysm Support Group This weekly program offers caregivers and people Where: Ronald Reagan UCLA Medical Ctr, Rm B130 The Brain Aneurysm Support Group is for patients experiencing memory loss the opportunity to learn Info: (310) 794-6644 memory techniques as well as strategies to lower diagnosed with an unruptured brain aneurysm, stress and stimulate the mind and the body. those having survived a ruptured aneurysm Novel Therapies in Cancer Treatment — and all caregivers, providing them information and Myths and Facts about Clinical Trials When: Call for dates and times education relating to the diagnosis, research, Where: UCLA Longevity Center, treatment options and recovery process. Lee Rosen, MD, UCLA Drug Development Program, will present how new drugs are 10945 Le Conte Ave, Ste 3119 When: Third Saturday, every other month, developed, how clinical trials are conducted Info: (310) 794-0680 starting May 16 / 9:30 – 10:30 am and when they can/should be used in cancer Where: Ronald Reagan UCLA Medical Ctr, 6th Fl, treatment. Classes of drugs just entering the ALZHEIMER’S DISEASE Conf Rm 6236 clinical arena and UCLA’s extensive list of Info: [email protected] clinical trials for a wide variety of cancer Beyond Alzheimer’s Support Group types will be discussed. Do you have a loved one with a memory problem When: Tuesday, August 11 / 7 – 9 pm or dementia? Is the stress of being a caregiver Where: Ronald Reagan UCLA Medical Ctr, Rm B130 overwhelming to you? A support group may be Info: (310) 794-6644 your answer. DID YOU MISS A LECTURE When: Tuesday and Thursdays (except holidays) / YOU WANTED TO ATTEND? Complementary Therapies for 6:30 – 8 pm Cancer Patients You can find videos of some of our past Where: UCLA Medical Center, Santa Monica, Lisa Kring, LCSW, Eileen Zegar, LAS, Dipl O.M., lectures and learn about hyperbaric 1250 16th St, Board Rm G210 Sibel Kantarci and Michael Sieverts will provide medicine, urinary incontinence, mindful Info: (310) 319-3222 information in the areas of meditation, awareness or sleep disorders. acupressure, Qi Gong and Reiki, and give Alzheimer’s Disease and Dementia Info: uclahealth.org/programvideos demonstrations on integrative therapeutic Learn how Alzheimer’s Disease and dementia are options to help improve the quality of life, diagnosed, differentiated from other health health, and wellness of cancer patients. conditions, managed and treated. When: Tuesday, September 29 / 7 – 9 pm When: Tuesday, September 8 / 2 – 3:30 pm Events in gold are offered near Where: Ronald Reagan UCLA Medical Ctr, Rm B130 Where: Westside Family YMCA, our UCLA offices in Malibu, Info: (310) 794-6644 11311 La Grange Av, Los Angeles Palos Verdes, Porter Ranch, RSVP: (800) 516-5323 Redondo Beach, Santa Clarita, Simi Valley, Thousand Oaks, Torrance and Westlake Village.

RESEARCH AND TRIALS UCLA conducts research for a wide range of medical disorders. Go online to learn more information about opportunities to participate in research and clinical trials. uclahealth.org/calendar

UCLAHEALTH.ORG 1-800-UCLA-MD1 (1-800-825-2631) Community Health Programs JULY, AUGUST, SEPTEMBER 2015

COPD HEART DISEASE

JULY, AUGUST, SEPTEMBER 2015 COMMUNITY HEALTH PROGRAMS Living With COPD WomenHeart West Los Angeles COPD affects an estimated 24 million people This peer-led support group is part of in the U.S. and over half have symptoms and WomenHeart, a national coalition for women don’t know it. Maryum Merchant, MD, UCLA with heart disease. Sessions will provide peer pulmonologist, will cover the basics of COPD, support, advocacy and education by leading including causes, risk factors, symptoms, professionals in the field. treatment options and how to manage an When: Monday, July 13 & September 14 / 7 pm exacerbation of COPD. Where: UCLA Cardiac Rehab Center, When: Wednesday, July 29 / 6 – 7:30 pm 200 UCLA Medical Plaza, Ste 206C Where: Camarillo Health Care District, Info: (310) 825-0014 3639 E Las Posas Rd, Bldg. E, Ste 117 FEATURED EVENT RSVP: (800) 516-5323 KIDNEY DISEASE 20TH ANNUAL UCLA RESEARCH Kidney Smart Classes CONFERENCE ON AGING This two-hour class focuses on how your kidneys The 2015 Research Conference on Aging, Living with function, ways to manage your diet and health to cosponsored by the UCLA Multicampus This ADA-certified eight-hour self-care class will promote healthy kidneys, and information about Program in Geriatric Medicine and kidney disease. Gerontology and the UCLA Longevity Center, help you gain important skills, knowledge and will demonstrate UCLA’s diverse research confidence to successfully manage your diabetes. When: July 16, July 30, August 13, August 27, efforts to enhance productive and healthy A physician referral is required. This class is September 10 and September 24 / 2 – 4 pm lifestyles for older adults. Research topics covered by most medical insurance policies. Where: 1821 Wilshire Bl, Suite 200, Santa Monica ranging from basic biology to public policy Info: (310) 794-1299 or Info & RSVP: (888) 695-4363 or kidneysmart.org will be presented. The event provides [email protected] the opportunity to network with others MEMORY conducting and interested in aging research Learning to Manage Gestational and will feature presentations from a Diabetes (ONGOING) diverse group of researchers in aging. This specialized 90-minute diabetes education Brain PETS: Scans for Early class is designed for expectant mothers who have Diagnosis and Treatment When: July 9 / 8 am – Noon been diagnosed with gestational diabetes, and it Daniel Silverman, MD, PhD, UCLA nuclear Where: Ackerman Grand Ballroom, offers information on meal planning, blood sugar 208 Westwood Plaza medicine physician, will talk about the loss many monitoring and long term health planning. This underlying causes for people with memory and geronet.ucla.edu/rcoa Info: class is covered by most medical insurance other thinking disabilities, and how and when to policies. A physician referral is required. use medical imaging of the brain to make the When/Where: Class is available weekly in earliest, most accurate diagnosis possible. Santa Monica, Westwood and Torrance CANCER (CONTINUED) When: Saturday, September 26 / 10 – 11:30 am RSVP: (310) 794-1299 or Where: Aegis of Granada Hills, 10801 Lindley Av [email protected] Colon Cancer Screening RSVP: (800) 516-5323 Michael Jean, MD, UCLA gastroenterologist, DIGESTIVE DISORDERS will discuss the risks, benefits and alternatives MIDWIFE SERVICES of different screening options for colon cancer. Nutrition for Common UCLA Midwives When: Monday, August 10 / 3:30 – 5 pm Digestive Disorders Where: Summerhill Villa, 24431 Lyons Av, Come and meet the UCLA Midwives and discuss Nancee Jaffe, RD, UCLA dietitian, will provide Santa Clarita UCLA services offered and ask questions. simple dietary and lifestyle tips to help manage When: Tuesdays, July 7, July 21, August 4, August RSVP: (800) 516-5323 common digestive conditions, such as diarrhea, 18, September 1 & September 15 / 1:15 – 2 pm constipation, gas/bloating and acid reflux. Where: 200 UCLA Medical Plaza, Rm 447 What Role Does Stress Play in When: Thursdays, 10:30 – 11:30 am Cancer Therapy? 1st Thursday – Diarrhea, RSVP: (310) 794-7274 2nd Thursday – Constipation, Shahryar A. Ashouri, MD, UCLA oncologist, will 3rd Thursday – Gas/bloating, discuss how stress and your immune system MULTIPLE SCLEROSIS 4th Thursday – Acid Reflux (GERD) play a role in cancer management. Where: Peter V Ueberroth Bldg, REACH to Achieve Program (ONGOING) When: Thursday, September 24 / 6:30 – 8 pm Conference Rm 1420, 10945 Le Conte Av This weekly wellness program focuses on fitness, Where: Cancer Support Community Valley/ RSVP: (800) 516-5323 memory, emotional well-being, recreation, Ventura/Santa Barbara, 530 Hampshire Rd, nutrition and health education for individuals Westlake Village with multiple sclerosis. RSVP: (800) 516-5323 Where: Marilyn Hilton MS Achievement Center Info & Application: (310) 267-4071

WEBINARS ON DEMAND If you missed one of our UCLA MDChat Webinars, visit our Webinars On Demand library to view programs led by UCLA physicians. For more info visit: uclahealth.org/uclamdchat

Vital Signs Summer 2015 Vol. 67 13 Community Health Programs JULY, AUGUST, SEPTEMBER 2015

MULTIPLE SCLEROSIS (CONTINUED) PODIATRY (CONTINUED)

Living Well Heel and Ankle Pain This 12-week program helps those newly Gary Briskin, DPM, will discuss the common diagnosed with multiple sclerosis to better causes of ankle and heel pain, including plantar understand MS and develop fitness and other fasciitis, arthritis, tendonitis and tendon tears. lifestyle practices to manage symptoms and Surgical and nonsurgical therapies, including enhance well-being. arthroscopy and shockwave, will be explored. Where: Marilyn Hilton MS Achievement Center When: Tuesday, August 18 / 5:45 – 6:45 pm Info & Application: (310) 481-1130 Where: 2121 Wilshire Bl, Ste 101, Santa Monica Free From Falls RSVP: (310) 828-0011 (date subject to change) FEATURED EVENT This eight-week program is designed for people Ankle Arthritis and Ankle Replacement with multiple sclerosis who walk and may be at Bob Baravarian, DPM, will discuss the latest WALK WITH A DOC risk for falling. Learn how to reduce fall risks, and advances in conservative and surgical treatment Join UCLA Health and walk toward a exercises to improve balance and mobility. of foot and ankle arthritis, including injection healthier lifestyle. Enjoy the opportunity to Where: Marilyn Hilton MS Achievement Center joint lubrication, arthroscopic cleanup, joint walk and chat with friends, neighbors and Info & Application: (310) 481-1130 preservation surgery, fusion surgery and ankle local UCLA Health physicians. Move at your replacement surgery. own pace (even if you need a walker or a When: Tuesday, September 15 / 5:45 – 6:45 pm wheelchair), and take an opportunity to PAIN TREATMENT chat with local UCLA Health physicians Where: 2121 Wilshire Bl, Ste 101, Santa Monica and others from the community. You don’t Back, Hip, Arm and Leg Pain RSVP: (310) 828-0011 (date subject to change) need any special gear and there are no J. Pablo Villablanca, MD, UCLA diagnostic special rules. Put on a pair of comfortable neuroradiologist, will explore the common OVARY SYNDROME shoes, head towards the beach and make cause of pain in the back, hips, arms and legs, strides to better health! the significance of specific symptoms, and PCOS Awareness Symposium When: Saturday, July 4, August 1 and the range of treatment options. Medical experts in Polycystic Ovary Syndrome September 5 / 10 am When: Wednesday, August 19 / 2 – 3:30 pm (PCOS) partner with PCOS Challenge Inc. to Where: Miramar Park, 201 Paseo De La Playa, Where: Belmont Village, 10475 Wilshire Bl discuss current scientific and clinical topics Redondo Beach (Meet at the dolphin statue RSVP: (800) 516-5323 regarding the origins, diagnosis and in the center of the park.) management of PCOS. Info: [email protected] PLASTIC SURGERY When: Saturday, July 25 / 9 am – 5 pm Where: Ronald Reagan UCLA Medical Ctr, B Level, Tamkin Auditorium Optimizing Nasal Appearance WEIGHT LOSS Jason Roostaeian, MD, UCLA plastic surgeon, will Info: pcoschallenge.org/symposium discuss the latest techniques and technologies and Weight Loss available to improve the appearance of your nose. TRIGEMINAL NEURALGIA Jennifer Chew, MD, UCLA internal medicine When: Thursday, July 30 / 7 – 8:30 pm Trigeminal Neuralgia (TN) physician, will address the growing epidemic Where: The Santa Monica Synagogue, 1448 18th St of obesity in the US, as well as the health RSVP: (800) 516-5323 Support Group ramifications directly related to obesity seen For patients diagnosed with TN and other facial in the primary-care setting. She will look at PODIATRY pain syndromes and their families to learn about the challenges of weight loss and offer diagnosis, investigation and treatment options. healthy approaches. Bunion and Bunion Surgery When: Third Saturday of every month starting, When: Tuesday, September 29 / 1 – 2:30 pm Bob Baravarian, DPM, will discuss bunions and May 16 / 10:45 – 11:45 am Where: Torrance-South Bay Family YMCA, the latest surgical and nonsurgical treatments for Where: Ronald Reagan UCLA Medical Ctr, 2900 W Sepulveda Blvd this common condition. 6th Fl, Conf Rm 6236 RSVP: (800) 516-5323 When: Tuesday, July 21 / 5:45 – 6:45 pm RSVP: [email protected] Where: 2121 Wilshire Bl, Ste 101, Santa Monica WELLNESS RSVP: (310) 828-0011 (date subject to change) VISION CARE East-West Primary Care Your Eyes — A User’s Manual Felicia Yu, MD, UCLA internal medicine clinical Events in gold are offered near Gavin Bahadur, MD, UCLA ophthalmologist, instructor, will give an introduction to the our UCLA offices in Malibu, will give an interactive and informative session primary-care model offered at the UCLA Center Palos Verdes, Porter Ranch, about the treatment of common eye conditions, of East-West Medicine, which combines Western including cataracts, glaucoma, macular medicine and traditional Chinese medicine. Redondo Beach, Santa Clarita, degeneration, dry eyes and others. Simi Valley, Thousand Oaks, When: Wednesday, September 2 / 7 – 8:30 pm When: Thursday, September 17 / Noon – 1:30 pm The Santa Monica Synagogue, 1448 18th St Torrance and Westlake Village. Where: Where: Santa Monica Family YMCA, 1332 6th St RSVP: (800) 516-5323 RSVP: (800) 516-5323

RESEARCH AND TRIALS UCLA conducts research for a wide range of medical disorders. Go online to learn more information about opportunities to participate in research and clinical trials. uclahealth.org/calendar

UCLAHEALTH.ORG 1-800-UCLA-MD1 (1-800-825-2631) Community Health Programs JULY, AUGUST, SEPTEMBER 2015

it begins with

UCLA HEALTH 50-PLUS IS A PROGRAM offering educational lectures, a walking Scan to find out program, information on community and health resources, membership amenities, more, or go to: a free community flu shot clinic and special events. To sign up, call (800) 516-5323. uclahealth.org/calendar

Senior Scholars (ONGOING) Understanding Medicare Fit Feet After 50 UCLA Longevity Center’s program for adults Learn what Medicare covers, what it doesn’t and Learn foot care tips and how to keep your feet over 50 to audit undergraduate courses. how to fill in the gaps. healthy after 50. Attend courses taught by UCLA’s distinguished When: Wednesday, August 5 / 7 – 8:30 pm When: Wednesday, September 9 / 7 – 8:30 pm professors and enjoy intergenerational learning. Where: The Santa Monica Synagogue, 1448 18th St Where: Santa Monica Bay Woman’s Club, When: Sign up for Fall Quarter classes in August RSVP: (800) 516-5323 1210 4th St Where: Locations vary on UCLA Campus RSVP: (800) 516-5323 Info: www.semel.ucla.edu/longevity/srscholars or Bone Health [email protected] or (310) 794-0679 Bone Health is a key component for remaining Posture and Ergonomics Cost: $150 for one course functional and independent as we age. Carolyn Oudiz, PT, UCLA physical therapist, will Erin Atkinson Cook, MD, UCLA geriatrician, discuss optimal posture in standing, sitting and Memory Training Course will talk about the diagnosis, prevention, lying down, and setting up a home computer area (QUARTERLY) and treatment of osteoporosis. and general stretches to do at a computer. Learn practical memory-enhancing techniques in When: Wednesday, August 12 / 7 – 8:30 pm When: Thursday, September 17 / 10 – 11:30 am a course designed for people with mild memory Where: Santa Monica Bay Woman’s Club, Where: Santa Monica Family YMCA, 1332 6th St concerns; not for those with dementia. 1210 4th St RSVP: (800) 516-5323 When: Two hours per week for four weeks RSVP: (800) 516-5323 Where: Locations vary  Osteoporosis — Info & Cost: (310) 794-0680 or  Ups and Downs of Strengthening Bones [email protected] or longevity.ucla.edu Blood Pressure Milica Simpson, MD, UCLA family medicine, Gopi Manthripragada, MD, UCLA cardiologist, will address how to keep your bones healthy as Westside Walkers: will explore what blood pressure means for you age, treatments for osteoporosis and how to Free Mall Walking Program your health, including causes, symptoms, reduce falls and fractures. Sign in at Macy’s storefront on level 2.5, Westside diagnosis and guidelines to treat high When: Monday, September 28 / Noon – 1 pm blood pressure. Pavilion on Pico Blvd between Overland Ave and Where: Malibu Senior Center, Westwood Blvd, West Los Angeles. When: Thursday, August 20 / 10 – 11:30 am 23825 Stuart Ranch Rd When: Tuesdays and Thursdays / 8 – 10 am Where: The Canterbury, RSVP: (800) 516-5323 Info: (800) 516-5323 5801 Crestridge Rd, Rancho Palos Verdes RSVP: (800) 516-5323 Fitness U UCLA S.A.I.L. (Stay Active and Independent Introduction to Qi Gong for Life), a fitness and education program led Qi Gong is an ancient Chinese system of exercise by UCLA physical therapists, is designed for that is used to awaken the body’s innate healing healthy seniors. powers by combining movement, massage, When: Mondays and Wednesdays / 2 – 3 pm meditation and breathing to improve strength, balance and posture. Where: YMCA Santa Monica/Westside Auditorium, 2019 14th St, Santa Monica When: Tuesday, August 25 / 1 – 2 pm Info & Enrollment: (424) 259-7140 Where: YWCA Santa Monica/Westside, 2019 14th St Cost: $40 per month for unlimited participation. First-time participants should arrive at 1:30 pm RSVP: (800) 516-5323 for physical therapy screening.

WEBINARS ON DEMAND If you missed one of our UCLA MDChat Webinars, visit our Webinars On Demand library to view programs led by UCLA physicians. For more info visit: uclahealth.org/uclamdchat

Vital Signs Summer 2015 Vol. 67 15 nonprofit organization u.s. postage PAID 405 Hilgard Avenue ucla Box 956923, Wilshire Center, Suite 1850 Los Angeles, CA 90095-6923

U.S.News & World Report’s Best Hospital Survey ranks UCLA the No. 5 hospital in the country and the Best in the West.

UCLA Medical Group awarded GOLD LEV E L ACHIEVEMENT Gold Level Achievement for clinical CALIFORNIA DEPARTMENT of MANAGED HEALTH CARE quality by the California Department of Managed Health Care.

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CHIEF MARKETING OFFICER Pattie Cuen DIRECTOR, MARKETING COMMUNICATIONS Judi Goodfriend EDITOR David Greenwald CALENDAR EDITOR Tiffani Q. Mendinueto MEDICAL EDITOR Robert Oye, md CONTRIBUTORS You have the power to make a difference! By making a gift to Partners for Care, you help Dan Gordon Shari Roan us fulfill our mission to deliver outstanding, compassionate care to every patient who ADVISORY BOARD comes through our doors. Share your power by becoming a member of UCLA Health’s Matteo Dinolfo, md Bernard Katz, md Partners for Care today. Janet Pregler, md Gary Small, md For more information about Partners for Care, or to make a gift, go to: uclahealth.org/pfc DESIGN or contact Brian Loew, director of development, Patient Programs, at (310) 794-7620 Donenfeld & Associates

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