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Siler & Platycodon Formula Fang Feng Tong Sheng

Siler & Platycodon Formula Fang Feng Tong Sheng

Origins: Liu Siler & Platycodon Formula Fang Feng Tong Sheng San Wan-su, 1172

Siler and Platycodon Formula (Fang Feng Tong Sheng San) originated in the Formulas from the Discussion Illuminating the ’s Basic Questions ( Di Su Wen Xuan Ming Lun Fang), published in 1172 c.. by Liu Wan-su. Liu is believed by some to have derived his inspiration for this formula from Ge San (Cool the Diaphragm Powder) published earlier in the same century. General Signs/Symptoms Traditionally, this formula was chiefly prescribed when the patient exhibited simultaneous manifestations of both interior and exterior heat. These signs and symptoms are reviewed here: Signs of External Heat Signs of Internal Heat Fever and chills together, sinus and nasal symptoms, High fever, constipation, dark rough urination, bitter headache, sore throat, cough, slightly dark urine, taste in mouth, glomus in chest or diaphragm, cough slightly inhibited urine, slight thirst, mild sweating, that produces pain in chest, dyspnea, rectal bleeding red eyes, cough, and heat rash. from heat, carbuncles, boils or suddenly appearing acne, clenched jaw, and generalized myalgia. Liu Wan-su recommended use of this formula with all wind-heat disorders that were accompanied with specific heat signs like constipation, dark, rough urination, facial sores, red eyes, or when the presence of heat has generated wind, resulting in a clenched jaw or stiff tongue. Today, the formula is chiefly used to treat hot- type influenza, red sores such as boils, carbuncles, or acne, bleeding rectum (sometime called “intestinal wind”), acute conjunctivitis, and as a general detoxifying formula.

Traditional Actions 1. Disperses 2. Drains and 3. Eliminates 4. Drains 5. Supports , 6. Unblocks heat purges wind dampness nourishes bowels from the heat-toxin blood exterior from the interior Ingredients Latin English Percent of Formula Gan (guide) Glycyrrhizae (radix) Chinese Licorice Root 21% Ze Xie (deputy) Alismatis (rhizoma) Asian Water Plantain Rhizome 12% Jie Geng (deputy) Platycodi (radix) Platycodon Root, Balloon Flower Root 10% Dong Kui Zi (deputy) Malvae (semen) Malva Seed, Whorled Mallow Fruit 10% Huang (deputy) Scutellariae (radix) Chinese Skullcap Root, Scutellaria, Scute 8% Fang Feng (co-chief) Saposhnikoviae (radix) Siler Root 4% (Jiu) Da Huang (co-chief) Rhei (radix et rhizoma) Chinese Rhubarb Root (wine-washed) 4% Bo He (deputy) Menthae haplocalysis (herba) Chinese Mint 4% Lian Qiao (deputy) Forsythiae (fructus) Forsythia fruit 4% Jing Jie (deputy) Schizonepetae (herba) Schizonepeta 4% Zhi Mu (deputy) Anemarrhenae (rhizoma) Anemarrhena Rhizome 4% Chuan Xiong (assistant) Chuanxiong (rhizoma) Ligusticum Wallichii Rhizome 3% Dang (assistant) Angelicae sinensis (radix) Dong Quai, Tang Kuei Root 3% Bai Shao (assistant) Paeoniae alba (radix) Chinese White Peony Root 3% Bai (assistant) Atractylodis macrocephalae (rhizoma) White Atractylodes Rhizome 2% Shan Zhi Zi (deputy) Gardeniae (fructus) Gardenia Fruit 2% Sheng Jiang (guide) Zingiberis recens (rhizoma) Fresh Ginger 2%

Siler & Platycodon Formula Monograph © March 2012, Herbal Medicine Press Siler & Platycodon Formula 2 per day.per adult 2-3tablets, dose is 2-3times hours after the fever broken), has the aboutfebrile 24 (beginning disease febrile disease, and for of sequella applications not involving acute dropped for at least 24hours. For this dosage until the fever been has tablets 3-4hours every and continue influenza, adults shouldtake 3-4 For acute conditions, such febrile as D heat. Do not to use treat deficiency. Do notthe in use absence excess of than 8weeks) contraindicated. is Extended/long-term (more use treatment when the patient strong. is or moderate-length courses of forcan used be acute conditions conditions. The present formulation only for short-term acute in use The classical versionindicatedis the one under present discussion. this formula alittle is harsher than loose stools. The classical version of with caution when the patient has purgative action and should used be percentage substances of with This formula contains a small C wiry, or rapid and rolling. andRapid flooding, or rapid and P Red tip with yellow coating. T F pregnancy. use not Do ongue ormula ulse ontraindications • Unblocksbowels qiandnourishesblood • Supports • Drains dampness • Eliminates wind • Disperses heat• Disperses from theexterior osage • Drains andpurges heat andtoxin from theinterior

A s ction d uring uring /C autions • Boils andcarbuncles • Boils • Bleeding, rectal • Bitter taste inmouth • Acne • Common cold, w/highfever • Cholesterol, high • Bronchitis, acute • Erysipelas • Cough • Constipation • Conjunctivitis, acute stances S in insights to efficientlyeliminate trapped heat.Together the sub difficultdisentangle. to strategiesdevised He that utilized these understanding that when heat trapped is the in body, it can be a major pathogenic factor. His insights were deepened by his (the 12 trapped heat. Its creator, Liu Wan-su, time his in visionary was Tong an ingenious San strategy part) is of to eliminate Every ingredient S in S G The version of S blood. andyin qi, assistant substances are added to protect the qiand ing thatthe other some of substances the in formula can consume factors have caused some damage to qiand fluids, and - recogniz dition, this formula of because use indicates that the pathogenic trappedis the in epithelial tissue (skin, intestines, bladder). In ad- either results from damage to the blood from heat, that or wind tion or prevent heat from moving out, and eliminate that wind and vent heat outward, drain dampness that can inhibit urina San) drain and purge heat from the interior, release the exterior codon). (jie geng Platycodon the one most) is (jie of powerful geng compensated for by more than doubling the percentage platy- of original formula eliminated. been and has been This omission has USA. Ephedra (ma huang) constituted only the about 3-4%of ephedra (ma huang), which currently is abanned substance the in modification the original. of The original formulation contained San ) underthis in paper discussion acarefully is Shen re-crafted • Glomusinchestor • Fever • Eyes, red andpainful • Hemorrhoids loss,• Hearing acute from ynergy of Ingredients eneral diaphragm wind-heat invasion th century) by being the first to perceive trapped heat as I ndications iler and P iler and P iler and P latycodon Formula (Fang Feng Tong Shen /M latycodon Formula (Fang Feng Tong odern latycodon Formula (Fang Feng A • Tinnitus, acute from wind- • Throat, sore • Sties • Sores, red, hot rashes, hot • Skin • Sinusinfections, withfever wind-heat • Rash, • Obesity symptoms• Menopausal • Mastitis • Jaw, tightness in • Influenza viral • Infection, • Itching • Hives • Hyperlipidemia pplications heat invasion

- - Siler & Platycodon Formula 3 ------), with with ), ) and and ) Fang Feng Feng Fang ( shi hua ). The replace The ). dong kui zi kui dong hua shi hua ) is the main purgative, purgative, main the is ) ) also assisting the Chi the assisting also ) ) and Chinese rhubarb rhubarb Chinese and ) ) protects the spleen from from spleen the protects ) ) replace talc ( talc replace ) ) as a mild purgative. mild a as ) ) is listed as a “guide” herb in herb “guide” as a is listed ) combine to hasfound ) been ) and talc ( talc and ) latycodon Formula latycodon ze xie ze P gan cao gan da huang da fang feng fang dong kui zi kui dong ) releases heat and dampness via dis dampness and heat releases ) da huang da gan cao gan cao gan gan cao gan ) has also retained its prominence. The The prominence. its retained also has ) iler and and iler ). In the original formulation, the two two the formulation, original the In ). S gan cao gan da huang da mulation. Not quite as cold nor as heavy as gypsum as heavy nor as cold quite Not mulation. drain ) can (zhi mu rhizome anemarrhena ), (shi the of virtue by entering warmers all three from heat Anemarrhena channels. kidney and stomach, lung, of benefits en - additional ) haszhi ( mu the rhizome the draining and fluids, generating yin, the riching yin Enriching downward. water driving by spleen ofAll clearing. heat strong body from the protects formula. this to essential are actions these of the chiefsubstances the each, 4% at only Though ( siler are formula ( were percentage highest the constituting substances ( root licorice sub these and explained, been has talc the for ment Licorice formula. of the part major a remain stances ( root sub two of these percentages high for justification stances, which are not the formula’s chiefs, is interest is chiefs, formula’s the not are which stances, recommend therefore He below.) Discussion” mula damp-draining/ and of purgative inclusion the ed formulation, present the In substances. unblocking ( rhubarb Chinese ( seed malva above, stated as while, ( rhizome alismatis ing. Liu Wan-su believed that once heat had become become had heat once that believed Wan-su Liu ing. usually would dampness that interior, the in bound believed He heat-clearing. with interfere and form the that and addressed be must dampness this that “For (See cleared. be to need of expulsion pathways ( seed malva the ( rhubarb nese ( root Licorice of assistant. role alsohas the it but formula, this Because Shen San Tong direc and channels multiple utilizing routes, parate primary 12 all enter to ability root’s licorice tions, all to formula the “guide” to is required channels assis As routes. these all through and channels these ( root licorice tant, of of other actions some the harsh the by damage supplements sweetness Its formula. the in substances herbs. of other actions the the harmonizes and qi ( root Licorice formula the in substances other with effectively most with Combined actions. focused powerful, for - - - - ), has in also been eliminated gypsum), gao (shi mula, moderate-length for safer formula the make to order out/purging clearing as when ofcourses treatment, ) possesses gao (shi Gypsum toxin. environmental acute is used best for and action cooling a strong as a is classified It disorders. heat -stage yangming recommended is therefore and substance, “very cold” heavy and “very cold” since use, short-term for only as- gypsum dam such easily ) can gao (shi substances must it Also, long. used too qi when stomach the age as such purgatives, when caution be used great with of part formula. the ) are huang (da Chinese rhubarb of influence gypsum cold the draw can Purgatives be can it where interior, the ) deeper into gao (shi ) (zhi mu rhizome Anemarrhena problematic. come for present gypsum) in the the gao (shi has replaced The other mineral substance from the original for original the from substance mineral other The for disseminating disseminating for materia medica in the substances the upon act to herbs other ascending qi and lung of is main sub one the It of part body. upper the from omitted substance ) is (hua shi another Talc is it problematic but banned, is not It original. the - contami to talc mine without is it difficult because ) was (hua shi talc Therefore, asbestos. from nation alismatis kui zi) and (dong seed malva with replaced kui of actions (dong The seed malva ). xie (ze rhizome unblock Both ). (hua shi talc similar to very zi) are (dong seed malva but dampness, drain and urination assists and swellings reduce can kui zi) additionally of that - assist action, The latter movements. bowel inclusion for ideal it makes movements bowel ing formula, Wan-su’s of version Liu modified in this - soft used a salt for ), xiao (mang mirabilitum because (dong seed Malva has also been omitted. stool, ening (mang mirabilitum than gentle more being kui zi), use. extended for safer formula the make ) helps xiao bland cold, ) is a sweet, xie (ze rhizome Alismatis dampness draining used for commonly substance It urine. the body through the from damp-heat and (dong seed malva assists the and urine the unblocks of) in actions (hua shi talc the the kui zi) in replacing formulation. present the stances for unbinding the throat from pain, toxin, toxin, pain, from throat the unbinding for stances - ef the geng (jie ) enhances Platycodon phlegm. and (bo mentha ), qin huang scutillaria ( of like fects herbs and toxin eliminate ) to qiao (lian forsythia and he), throat. and warmer upper the from heat Siler & Platycodon Formula 4 uty,), he apowerful is mentha (bo substance leaf threeall warmers through the urine.finaldep The heat. It famous is for being able to clear heat from Gardenia adeputy zi)is for (zhi clearing internal common to do so. substance the one chiefs, as of though not it is external heat. It would justified be to regard this (lian qiao said) is to eliminate both internal and ing heat the in skin, throat, and heart that forsythia the skin can external. be It eliminat- by is virtue of ternal, but heat that trapped is the in throat and in to the throat. All heart fireis considered in- be to herb for toxic swellings/sores and agreat benefit urine. Forsythia (lian qiao considered) is a “sagely” chest and throat and 2)by draining it through the heart fire andso by1) does venting the it out of efits thegallbladder. a strongIt has action to clear from the upper warmer and throat, but- ben also especiallyis effective at clearing and venting heat (SchoolWarm of the in Disease) late 1600s. It comes amajor substance the in Wen BingSchool qiao deputies. as ) serve Forsythia (lian qiao) be herb.) and he forsythia Mentha (bo fruit (lian leaf three are assistants, and one an second is guide the remainingOf ingredients, three are deputies, the formula.part of tions, especially when (jing schizonepeta jie also ) is the flesh, these two herbs support one another’s ac- formation. For wind-heat and toxin expressing in rashes and resolve their in boils initial stages of trapped the in flesh andused windbe can to expel will not heal.will Siler (fang that wind ) expels feng is to used is resolve fire toxin and soresrepair that through its supplementation the spleen of and for the flesh.Licorice (gan cao ) nourishes the flesh rice (gan cao) and siler (fang) have feng an affinity fluid-generating properties this herb. of Both lico licorice root cao) (gan thought is to bring out the When combined with anemarrhena mu (zhi ), (shi gao) andboth anemarrhena gypsum mu (zhi ). It frequently is to used moderate the cold from for treating apainfully blocked throat (throat). bi created. Jie Geng Tang ahighly is effective formula platycodon), (jie geng the formula Jie Geng Tang is muscle pain and reduce spasms. Combined with Shao Yao Gan Cao Tang, to used stop cramping white peony (bai shao), the two make the formula: - - - than afew days or when the digestion weak. is important when the treatment course of more is mula and to “take it in” (absorb it).is especially This cao). It helps the to body tolerate the the rest for of middle warmer and harmonizes, like licorice (gan jiang) can release the exterior; protects it also the taken with ginger, which separate. was Ginger (sheng the formula ground was together into apowder and root jiang (sheng ). In Liu’s formulation, the rest of mula (Fang Feng Tong San the) is Shen “guide” ginger finalThe substance inS on the other. propertiesdamaging the heat-clearing of substances dampness on the one hand, and protect it from the ),zhu adirect is strategy to rescue the spleen from inclusion The assistantthe herb,of atractylodes (bai rashes are more speedily resolved. assistants, eliminated is wind and toxic sores and nourishing and invigorating the blood with these but addresses it also residing wind the in blood. By wind. This formulapulsion of treats externalwind, protect the blood. Strong blood facilitates the ex- with the already mentioned peony (bai shao), help (chuanticum xiong ) and angelica ( dang), gui along Two the remaining of assistant substances,- ligus lesser degree, forsythia (lian qiao). (jingschizonepeta jie), jiang) ginger ( sheng , and to a to release exterior heat along with siler (fang), feng throat present. is It an essential the is strategy part of treat wind-heat invasions, especially when sore (jingschizonepeta jie) and forsythia ( lian qiao) to the body.part of It frequently is combined with for releasing the exterior and cooling the upper primary pathogenic factor. He believed that ex all - contended that it heat, was not cold, that the was thoughtof on externally-contracted diseases. He thinking departed from the Lun school reallywas his core abranch just of theories. off His work.) But approach his to treating epidemic disease the Wen School greatly revered Liuand his ential Wen Bing School by some 500 years. (In fact, febrile with cold disease herbs, preceding the influ- He proponent the was chief for treating epidemic formula than simply treating hot-type influenza. Liu Wan-su envisioned abroader application his of Formula Discussion iler and P latycodon For - - Siler & Platycodon Formula 5 - - - - laty i iler and P and iler latycodon For latycodon iii Formula latycodon ii - (Fang Formula latycodon iler and P and iler Fang Feng Feng (Fang Formula latycodon iler and P and iler iler and P and iler pplications A iler and P and iler tching ) as a basic strategy for releasing releasing Shen for ) as strategy San basic a Tong from heat releasing body by the from heat trapped - drain by and terrain, external and bowels, chest, the be trapped. may heat where dampness the out ing spleen the protect to was important it also felt He ofall body fluids, asas blood well replenish qi and when consumed or damaged become can which born have centuries few The last heat. is excess there fully. more formula this vision for broad Liu’s out S era, modern the In treat to Shen) is used San frequently Tong Feng (Fang pathogenic involve that ofa wide variety conditions signs with of interior in the trapped toxin or heat applications Some common exterior. in the heat fe and chills, sweating, with poisoning food include body, the from toxins of environmental removal ver, tendency a and/or constipation with inflammation chronic arteriosclerosis, bronchitis, boils, develop to with inflammation sinus dermatitis, hot-type acne, - hem urination, dark or constipation accompanying itching. wind-heat and heat, summer orrhoids, ) to treat migraines, migraines, Sheng treat ) to San Tong Feng (Fang mula and intensity lower reported 80% of participants the of frequency symptoms. lower I were itching with patients 40 elderly a 1992 study, In S with treated were ofAll participants the Sheng). San Tong Feng of 35 out itching. pattern wind-heat diagnosed with relief. complete 40 reported the Modern Modern as such applications, of a number Besides traditional more, and conjunctivitis, influenza, hot-type boils, - appli the for studies has conducted research modern ofcation S areas: following Sheng) in the San Tong Migraines and Headaches per with 27 patients in 1977, conducted a study In S using a 1989 study In sistent headaches were treated with S with treated were headaches sistent 19 Sheng). San Tong Feng (Fang Formula codon after recurrence no with recovery complete reported improvement marked showed 5 Another 6 months. frequency. and intensity reduced with - - - Fang Feng Feng (Fang Formula latycodon Fang Feng Tong Tong Feng (Fang Formula latycodon iler and P and iler iler and P and iler Liu saw S Liu saw ers the water, it will be cooked into dampness and and dampness into will it be cooked water, the ers thinking, Liu’s In stagnation. create can dampness where in conditions factor is a common dampness needs water the Frequently, is present. heat excess to out drained dampness the and be unblocked to the address to Failure heat. the clear successfully of the clearing in incomplete result may dampness a to a blaze from it transforming merely often heat, heat relocated: be also simply may heat The smolder. in heat throat; in the heat becomes often lungs in the heat. intestinal becomes often stomach the tempt to put the fire out or keep it from spreading— it keep from or out fire the put to tempt if overpow heat the heat, contacts water the once Liu believed strongly in looking for signs of for damp in looking strongly Liu believed ), because it is clearing both deep-lying and and deep-lying both is it clearing because Shen), San all unblock that substances includes heat, superficial of the out body: the vents it of pathways major the unblocks it layer, skin the releases body and upper urination. disinhibits and bowel, the cesses in the body eventually produce or transform transform or produce body eventually in the cesses could that strategies emphasized he and heat into of part As he his strategy body. the from heat clear route. exit an had heat the that sure make would S - suf Without conductive. and cooling is both Water has interior the in trapped is that heat water, ficient has that is water Dampness exit. its for medium no heat pathogenic to exposure by either turbid become Our movement. insufficient from stale growing by or - at heat—an to as a response water bodies solicit ness, because he believed that heat cannot be cleared be cleared cannot heat that believed he because ness, be difference The properly. if flowing is not water When is movement. “body fluids” and “water” tween - suf about talking are we body fluids, talk about we nourishment provide to moisture thin clear, ficient talking are we “water” talk about we When tissues. to of - nourish instead its but fluid, same the about course to ability its to referring are we capacity, ing is or “stagnates” water pathology, In conduct. and - “path called are territories associated its “blocked;” “damaged,” are hand, other the on Body fluids, ways.” - terri their associated “insufficient;” or “consumed,” body damage can heat Pathogenic tissues. are tories need fluids Body stagnate. to water cause and fluids need pathways water replenished; or be preserved to be unblocked. to 6 Menopausal Symptoms formula on body fat accumulation and elevated tri- A Taiwanese clinical study, that included 3,432 glyceride levels due to a high fructose diet. An experi- women, ages 39-70 years, documented treatments mental group of female rats were fed a high fructose ormula for menopausal symptoms with 20 possible TCM diet that had been proven to raise triglyceride levels F formulas. These women were treated based on their and cause weight gain. This study concluded that rats TCM diagnosis. Several different formulas and who had been fed a fructose-loaded diet, did not gain single herb modifications were adminstered for 1-3 weight or experience elevated triglyceride levels when weeks, at a variable dosage of 1-4 times daily. Siler fed -tsusho-san (Siler and Platycodon For- latycodon and Platycodon Formula (Fang Feng Tong Sheng mula/Fang Feng Tong Sheng San). The formula was iv

& P San) was the fourth most often prescribed formula. shown to inhibit triglyceride synthesis in the liver, enhance lipolysis in adipocytes, and enhance thermo- iler Obesity and Reduced Cholesterol S genesis of brown adipose tissue, which prevented a A study for treatment of simple obesity conducted rise in triglyceride levels and body fat accumulation.viii in Japan in 2005 showed a reduction in liver lipids contributing to fatty liver, total cholesterol, and Constipation triglycerides as a result of simultaneous administra- A study, conducted by the National Health Insurance tion of Siler and Platycodon Formula (Fang Feng Research Institute in Taiwan to determine the most Tong Sheng San) and colestimide. There was also a commonly prescribed herbal medicine for constipa- reduction of body mass (weight loss). No undesir- tion, gathered information on over 150,000 patients. able side effects were reported.v A combination of Siler and Platycodon Formula (Fang Feng Tong Sheng San) and Ma Zi Ren Wan, Another Japanese study, published in 2001, found with added da huang, was found to be the most com- that Fang Feng Tong Sheng San (Siler and Platy- mon 3-herbal prescription.ix codon Formula) was very effective in suppressing fat accumulation and body weight gain in mice that Formula Comparisons had ovariectomy-induced obesity. The results of the Siler and Platycodon Formula and Yin Chiao study indicate that weight control may have been Formula achieved by enhancement of the thermogenesis of Both of these formulas can treat exterior wind-heat brown adipose tissue, stimulated by administration symptoms and toxic heat symptoms affecting the of Siler and Platycodon Formula (Fang Feng Tong head, eyes, and skin. Yin Chiao Formula (Yin Qiao Sheng San). vi San) specifically treats early-stage wind-heat invasion when the primary symptom are mild sore throat, red Obesity and Metabolic Syndrome eyes, wind-heat skin inflammation, headache, or con- A Japanese study completed in 2005 studied 81 junctivitis, in the early stage of onset. When a wind- obese women who had been diagnosed with im- heat invasion has penetrated the exterior and caused paired glucose tolerance (IGT). The results of the interior yangming heat symptoms such as constipa- study showed that the administration of Bofu- tion and heat in the blood level with skin eruptions, tsusho-san (Siler and Platycodon Formula/Fang and is not completely resolved on the exterior, then ) produced a significant weight Feng Tong Sheng San the use of Siler and Platycodon Formula (Fang Feng and body fat reduction, as well as inches lost in the Tong Sheng San) is a more appropriate treatment. waist and hips as measured before and after the 24- week trial. In addition to weight loss, decreases in Siler and Platycodon Formula and Zhong Gan total cholesterol, triglycerides and specifically LDL Ling Formula (“bad”) cholesterol were noted. The HDL (“good”) These two formulas can treat similar wind-heat cholesterol value increased in the group treated and toxic-heat symptoms, including swollen lymph with Bofu-tsusho-san.vii glands, conjunctivitis, severe cold and hot-type influ- enza. If additional interior heat symptoms are pres- High triglycerides (hypertriglyceridemia) ent such as constipation and blood-level heat, com- A study conducted and published in Japan in 2001 bined with unresolved exterior wind-heat symptoms was designed to study the effects of a Kampo herbal then Siler and Platycodon Formula (Fang Feng Tong Siler & Platycodon Formula 7 - is Sheng San) Tong Feng (Fang latycodon Mulberry and and Mulberry and Formula latycodon iler and P and iler iler and P and iler . Formula and Pinellia with Fritillaria Use with Nourish Siler and Platycodon Use in a 2:1 ratio. Formula Essence tion, so if the manifestations are more generalized, generalized, more are so if manifestations the tion, S formula. preferred the S Formula Lycium treating for effective highly are of formulas Both these Formula Lycium and Mulberry influenza. hot-type - dislodg for strategy direct ) is a more San Bai (Xie superior is and tissue, lung the flu virus from the ing such respiratory, chiefly are manifestations the when body aches accompanying with cough, or as wheezing Bai (Xie Lycium and Mulberry pulse. racing and stagna damp or constipation address ) does not San ombinations - C elieve elieve elieve elieve seful optis R U optis R (Huang Lian Jie Jie Lian (Huang Formula oxicity T ) usually does not need to be combined, be combined, to need does Sheng not ) usually San Tong Feng (Fang Formula latycodon latycodon Formula and C and Formula latycodon elieve elieve Vol. 117, Issue 1, pp. 77-86, 2001. 77-86, pp. 1, Issue 117, Zasshi , Vol. Yakurigaku Nihon rats,” in fructose-loaded accumulation body fat , Vol. 73, Issue 7, 7, Issue 73, Vol. , Association Medical of the Chinese Journal Taiwan,” in Insurance Health National the under Constipation 2010. July 375-383, pp. Vol. 109, pp. 63-66, 2010. 63-66, pp. 109, Obstetrics, Vol. and of Gynecology Journal International Vol. 4, pp. 92- pp. 4, , Vol. y Aromaticas Medicinales Plantas de Caribe y del Latinoamericano Boletin syndrome,” metabolic with subjects 2005. September 97, Vol. 17, Issue 4, pp. 17-24, 2001. 17-24, pp. 4, Issue 17, , Vol. Eastern Medicine in mice,” obesity induced Vol. 19, pp.1029-1034, 2005. pp.1029-1034, 19, , Vol. Vivo In Diet”, a High-fat Fed in Mice Lipids Liver and Plasma Morimoto, Y, Sakata, M, Ohno, A, Maegawa, T, Tajima, S, “Effects of bofu-tsusho-san, a traditional Chinese medicine, on medicine, Chinese “Effectstraditional a of bofu-tsusho-san, S, Tajima, T, Maegawa, A, Ohno, M, Sakata, Y, Morimoto, optis R Volume 6, Issue 17, 1989. 17, Issue 6, , Volume Medicine of Chinese Journal Hioki, C., Yoshida, T., “Usefulness of a Japanese Herbal Medicine, “Bofu-tsusho-san” with tailor-made diet therapy in therapy diet tailor-made with “Bofu-tsusho-san” Medicine, Herbal of“Usefulness a Japanese T., Yoshida, C., Hioki, does not address address does not Pian) Jie Lian (Huang oxicity Formula oxicity iler and P and iler iler and P and iler Volume 1, Issue 33, 1992. 33, Issue 1, , Volume Medicine Chinese of Traditional Journal Heilongjiang Jong, M-S, Hwang, S-J, , Y-C, Chen, T-J, Chen, F-J, Chen, F-P, “Prescriptions of Chinese Herbal Medicine for for Medicine of“Prescriptions Chinese Herbal F-P, Chen, F-J, Chen, T-J, Chen, Y-C, Chen, S-J, Hwang, M-S, Jong, Akiko, O., Michiko, S., Yasuo, M., Sigeru, T., “Effects of Bofu-tsusho-san (Fang Feng Tong Sheng San) on ovariectomy- on San) Sheng Tong Feng “Effectsof (Fang Bofu-tsusho-san T., Sigeru, M., Yasuo, S., Michiko, O., Akiko, Chen, L-C, , B-R, Chen, I-C, Shao, C-H, “Use of Chinese herbal medicine among menopausal women in Taiwan,” Taiwan,” in women menopausal of among “Use medicine Chinese herbal C-H, Shao, I-C, B-R, Chen, Wang, L-C, Chen, For influenza when phlegm in lungs is severe influenza when phlegm For the yin from protect to use long term For damage Volume 2, Issue 82, 1977. 82, Issue 2, , Volume Medicine of Chinese Journal Tianjin Sakamoto, S, Takeshita, S., Sassa, S, Suzuki, S., Ishikawa, Y., Kudo, H., “Effects of Colestimide and/or Bofu-tsusho-san on “Effects Bofu-tsusho-san and/or of Colestimide H., Kudo, Y., Ishikawa, S., Suzuki, S, Sassa, S., Takeshita, S, Sakamoto, ix vi vii v ii iii iv i viii any external wind-heat symptoms because the heat heat the because symptoms wind-heat external any internalized completely become has already pathogen levels. yangming and shaoyang the to T S clinical certain for be made may emphasis However, aspects so of heat. many trapped addresses it since manifestations: - particu also shao- targets symptoms, Du Pian) as heat, gallbladder and liver by caused those larly The symptoms. heat level blood and aswell yangming involve could formula this by addressed symptoms Gener burners. all three or burners of three any the These two formulas treat some of the same interior of interior same some the treat formulas These two asboils, such symptoms level blood and yangming glands. swollen and sties, rash, heat hives, carbuncles, C T C severe. more is much heat the ally S is the more appropriate formula. formula. appropriate more is the Sheng San) Endnotes Siler & Platycodon Formula 8 Scott, J., Monda, L.,and Heuertz, J. Clinical Guide toCommonly Used Chinese Herbal Formulas, 5 Schied, V., Bensky, D., Ellis, A., and Barolett, Chinese Herbal R. Medicine: Formulas &Strategies, 2nd ed.Seattle, WA: Ellis, A. Notes from South Mountain: AGuide toConcentrated Herb Granules. Berkeley, CA:Thin Moon, 2003. Chen, J. &Chen, T. Chinese Medical. and Industry, Herbology Pharmacology City of CA, MedicineArt of Press, 2004. Chen, J. &Chen, T. Chinese Herbal Formulas and Applications. Industry, City of CA, MedicineArt of Press, 2009. Bensky, D., Clavey, S., Stoger, E., &Gamble, A. Chinese Herbal Medicine: Materia Medica R ef cine Press, 2009. Eastland Press, 2009. land Press, 2004. erences

, 3 rd ed.Seattle, WA:- East th ed., Herbal Medi-