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Current Medical Literature Ysis in Presence of Carbohydrates and of Aldehyds 36 Origin of Humin Formed by Acid Hydrolysis of Proteins. Hydrol¬ Current Medical Literature ysis in Presence of Carbohydrates and of Aldehyds. R. A. Gortner, St. Paul.—p. 177. 37 *Uric Acid Solvent Power of Normal Urine. H. D. Haskins, Port¬ AMERICAN land, Ore.—p. 205. 38 Penetration Acids. Further Observations on Blue marked Cell by Pigment Titles with an asterisk (*) are abstracted below. of Chromodoris Zebra. W. J. Crozier.—p. 217. Annals of Ophthalmology, St. Louis 39 Id. Data on Some Additional Acids. W. J. Crozier.—p. 225. 40 *Feeding Experiments on Substitution of Protein by Definite Mix¬ July, No. 3 XXV, , tures of Isolated Amino-Acids. H. H. Mitchell, Urbana, 111.— 1 Intradural Tumor of Optic Nerve. E. C. Ellett, Memphis, Term. p. 231. —p. 435. 41 *Digestibility and Utilization of Egg Proteins. W. G. Bateman, 2 Resume of Experiments on Effects of Different Conditions of Light¬ New Haven, Conn.—p. 263. ing on Eye. C. E. Ferree and G. Rand, Bryn Mawr, Pa. —p. 447. 23. Surgery and Renal Permeability.—Operative procedures H. 3 Spontaneous Absorption of Opacities in Crystalline Lens. S. under anesthesia cause an increase in the blood sugar content 457. Brown, Philadelphia.—p. associated with a reduction or 4 Sclerocorneal Trephining Operation for Glaucoma. Report of (hyperglycemia), impairment Forty-Five Operations. W. R. Parker, Detroit.—p. 467. of renal function. From this it is concluded by the authors 5 Epibulbar Sarcoma. E. B. Heckel, Pittsburgh.—p. 474. that diminished permeability of the kidneys is responsible 6 Six Cases Treated with Tuberculin, Including Cases of Keratitis, for the infrequent elimination of sugar in the urine after Choroiditis and Cyclitis. C. A. Clapp, Baltimore.—p. 478. 7 Optic Neuritis from Syphilitic Leptomeningitis. W. H. Wilder, operation. Chicago.—p. 489. 24. Comparative Study of Proteolysis.—It has been demon¬ 8 Miners' Nystagmus. F. L. Hoffman.—p. 503. strated that pepsin is the effective agent in pepsin hydro¬ chloric acid since acid alone in the Arkansas Medical Society Journal, Little Rock digestion hydrochloric concentrations ordinarily employed has very little proteolytic August, XIII, No. 3 effect. As a result of a series of experiments the conclusion 9 Arteriosclerosis. F. B. Little 45. Young, Rock.—p. seems to Frankel that results in 10 Common Fallacies in Technical Diagnosis of Indigestion. E. D. justified comparable proteol¬ Holland, Hot Springs.—p. 48. ysis studies are to be obtained only when the substrates are 11 Differentiation Between Upper (Central) and Lower (Peripheral) in solution ; otherwise deviations of 10 to 15 per cent, may be Motor Neuron Involvement. G. B. Fletcher, Little Rock.—p. 50. encountered in duplicate experiments. An examination of the of thirteen shows that there is a Boston Medical and Surgical Journal digestion proteins parallelism in the cleavage curves of all the proteins, if the August 24, CLXXV, No 8 cleavage is calculated as the ratio of the amino nitrogen 12 of Mind. B. P. Croft, 251. Hygiene Greenfield.—p. liberated at one time to that obtained on total 13 Mental Preparedness. J. J. Putnam, Boston.—p. 260. any hydrolysis 14 Meaning of Mental Hygiene Movement. W. ., White, Washing¬ of the protein with strong acid. Pepsin hydrochloric acid can ton, D. C—p. 264. liberate about 20 per cent, of the total amino nitrogen of a 15 Mental Heredity. Menace of Deficiency from Standpoint of in less than 100 hours. Trypsin acting on H. H. Goddard, Vineland, N. J.—p. 269. protein proteins a 70 16 Functions of Social Service in State Hospitals. H. Curtis, partially digested with pepsin effects cleavage of about Hathorne.—p. 271. per cent. The action of trypsin on native proteins can cause a cleavage of about 50 per cent, of the peptide linkages. of Medical and of Bulletin Chirurgical Faculty Further addition of trypsin may cause further disintegration Maryland, Baltimore of the protein. Erepsin following the action of pepsin is a June, VIII, No. 12 very effective agent in causing the disruption of the protein 17 Dispensary Abuse and Certain Problems of Medical Practice. molecule. In two series of experiments cleavage of about W. Baltimore,—p. 229. J. Williams, 85 per cent, of the protein could be demonstrated. The Florida Medical Association Journal, Jacksonville successive action of pepsin, trypsin and erepsin liberates August, III, No. 2 about 85 to 90 per cent, of the total amino nitrogen of the studied. 18 Lumbar Puncture and Examination of Spinal Fluid. R. N. Greene, protein Chattahoochee.—p. 33. 26. of Phenols.—The results of Dubin's investi¬ ' Physiology Reaction. E. 19 Interpretation of Wassermann W. P. Dey and G. in addition to the of Henson, 40. gation, confirming findings Folin, bring Jacksonville.—p. to of 20 Diagnosis and Treatment of Syphilis. J. E. Gammon, Jacksonville. light some interesting observations. The elimination —p. 43. phenols from day to day is quite constant. Withdrawing R. 21 Few Facts Concerning Complement. J. Bean, Jacksonville.— water from the diet causes an increased phenol elimination. p. 48. After Eck fistula, the free phenols represent as high as 97 Journal of Biological Chemistry, Baltimore per cent, of the total, the latter, as also the former, exhibiting August, XXVI, No. 1 a tendency to decrease. After intestinal obstruction, there 22 Quantitative Comparison of Casein, Lactalbumin and Edestin for is an increase in both free and total phenols, the former con¬ T. B. and L. B. Mendel, Growth or Maintenance. Osborne stituting as low as 55 per cent, of the latter. In pancreatic New Conn.—p. 1. Haven, there is an increase in both free and total 23 *Effect of Surgical Procedures on Blood Sugar and Renal Per¬ insufficiency, meability. A. A. Epstein, J. Reiss and J. Branower, New phenols with an accompanying decrease in the percentage of York.—p. 25. free phenols. After excluding the bile, both free and total of Proteins Toward Pro- 24 *Comparative Study of Behavior Purified but with an increase in the of E. M. New Haven, 31. phenols increase, percentage teolytic Enzymes. Frankel, Conn.—p. The of 25 Metabolism of Sulfur. Relative Eliminations of Sulfur and free phenols. feeding phenol and p-cresol results Nitrogen in Dog in Inanition and Subsequent Feeding. B. normally, with but slight variations, in the elimination of Lewis, Urbana, 111.—p. 61. about 65 per cent, and 40 per cent., respectively. After Eck H. 69. 26 ^Physiology of Phenols. Dubin, Philadelphia.—p. fistula, about the same excretion is noted. After intestinal 27 ^Influence Carbohydrate, Protein and Fat on Blood of Ingested and exclusion of Sugar in Phlorizin Diabetes. F. A. Csonka, Pittsburgh.—p. 93. obstruction, pancreatic insufficiency, bile, 28 Researches on Pyrimidins. Synthesis of Thymine-4-Aldehyd. there is in both cases a drop in the amount excreted. The T. B. Johnson and L. H. Cretcher, Jr., New Haven, Conn.— feeding of tyrosin results normally in an excretion of about 99. p. ' 14 per cent., as phenols. After Eck fistula, the 29 Cerebronic Acid. Relation of Cerebronic and Lignoceric Acids. practically P. A. Levene and C. J. West, New York.—p. 115. same amount is eliminated. 30 Dialysis of Trypsin and Proteoclastic Action of Protein Cleavage After exclusion of bile and pancreatic juice, about 20 per Products. C. Funk, New York.—p. 121. cent, of ingested tyrosin is eliminated. Feeding of any of 31 Influence of Alcohol and Glycerol on Rate of Solution of Ethyl the three substances causes an increase in the conjugation at Casein by Sodium Hydroxid. Robertson and K. Miyaké, Berkeley, Calif.—p. 129. all times—p-cresol to a greater degree than phenol, and the 32 Chondrosamine. P. A. Levene, New York.—p. 143. latter to a greater extent than tyrosin. Tyrosin, phenol 155. 33 Synthesis of Hexosamines. P. A. Levene, New York.—p. and p-cresol, fed in amounts of 5 gm., 1 gm. and 1 gm., 34 Action of Glucal. J. O. Balear, Chicago.—p. 163. Physiologic were all eliminated within hovrs. 35 Formation of d-Lactic Acid by Autolysis of Pus. H. Ito, Japan. respectively, twenty-four —p. 173. No unchanged tyrosin could be demonstrated in the urine or Downloaded From: http://jama.jamanetwork.com/ by a University of Manitoba User on 06/19/2015 feces. Fasting reduces the phenols to a low level; the injec¬ amino-acids have specific functions in metabolism aside from tion of phlorizin during fasting causes an increase in the that of serving simply as material for the synthesis of body output of phenols. It is impossible to free the urine entirely protein. of phenols by the use of calomel. The bile appears to have 41. Utilization of Egg Proteins.—Raw egg-white, Bateman some influence on the conjugating function of the liver. The says, is a decidedly indigestible substance. It may cause phenols can be taken as an index of intestinal putrefaction. diarrhea in dogs, rats, rabbits and man when ingested in 27. Phlorizin Diabetes.—Following the ingestion of 20 gm. any large quantity. Its utilization by the body is poor since of glucose the blood sugar reached the maximum at the it is used only to the extent of 50 to 70 per cent. Subjects second hour, and declined to the original level at the fourth can acquire a certain tolerance for the native protein after hour. In another experiment, it was shown that of 16 gm. ingesting it for several days so that it no longer causes diar¬ of glucose given to a phlorizinized dog, 94 per cent, was rhea and is somewhat better utilized. Raw egg-white can excreted during the first five hours as extra glucose. The be made digestible through coagulation by heat; by pre¬ curve of the blood sugar content runs parallel with the curve cipitation with alcohol, chloroform, or ether; by incubation of the extra glucose.
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