Rabbit Anti-NUFIP1/FITC Conjugated Antibody

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Rabbit Anti-NUFIP1/FITC Conjugated antibody

SL19541R-FITC

Product Name: Anti-NUFIP1/FITC Chinese Name: FITC标记的NUFIP1蛋白抗体 bA540M5.1; Nuclear FMRP interacting protein 1; Nuclear fragile X mental retardation Alias: interacting protein 1; nuclear fragile X mental retardation protein interacting protein 1; NUFIP. Organism Species: Rabbit Clonality: Polyclonal React Species: Human,Mouse,Rat,Chimpanzee, ICC=1:50-200IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 70kDa Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human NUDT9 Lsotype: IgG Purification: affinity purified by Protein A Storage Buffer: 0.01Mwww.sunlongbiotech.com TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. background: This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association Product Detail: with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12. [provided by RefSeq, Feb 2012] Function: NUFIP1 contains 1 C2H2- type zinc finger and binds RNA. It interacts with FMR1. NUFIP1 may be associated with preinitiation complexes, open transcription complexes, and elongation complexes. It may facilitate ATP-dependent dissociation of hyperphosphorylated pol II from open transcription complexes.

Subcellular Location: Nuclear

Database links:

Entrez Gene: 26747 Human

Omim: 604354 Human

SwissProt: Q9UHK0 Human

Unigene: 525006 Human

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.