Supply Issues Update for Primary and Secondary Care: May 2021
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COMMERCIAL-SENSITIVE Supply Issues Update for Primary and Secondary Care: May 2021 This report has been produced by the Department of Health and Social Care (DHSC) Medicine Supply Team. We aim to produce this report monthly to provide an update on current primary and secondary care medicine supply issues that we are working on. This information is confidential to the NHS; please do not upload to websites in the public domain. Please do share with relevant colleagues and networks. Where it has been stated ‘a Serious Shortage Protocol (SSP) has been issued’, this will be found here. Tenecteplase (Metalyse) 10,000 units Contents powder and solvent for solution for injection New Issues ............................................................. 3 .......................................................................6 Injectables ......................................................... 3 Tetracosactide 1mg depot injection ..............6 Calcitonin (salmon) 50units/1ml solution for Urokinase (Syner-KINASE) 25,000IU injection injection ampoules ........................................ 3 .......................................................................6 Diamorphine 5mg and 10mg injection .......... 3 Verteporfin (Visudyne) 15mg powder for Orals ................................................................... 3 solution for infusion .......................................6 Irbesartan 300 mg/hydrochlorothiazide 12.5 Orals ...................................................................6 mg (CoAprovel) tablets .................................. 3 Cloral betaine 707mg tablets .........................7 Naftidrofuryl 100mg capsules ....................... 4 Chloral hydrate 143.3mg/5ml oral solution ..7 Others ................................................................ 4 Colestipol (Colestid) orange and plain 5g Fluticasone (Flixotide) 100microgram granules sachets ............................................7 Accuhaler ....................................................... 4 Colestyramine (Questran) Powder for Oral Gemeprost (Cervagem) 1mg pessary ............ 4 Suspension .....................................................7 Ongoing Issues ....................................................... 4 Contraceptive products (oral) ........................7 Injectables ......................................................... 4 Docusate sodium 100mg capsules .................8 Adrenaline Auto-Injectors (AAIs) ................... 4 Donepezil 10mg orodispersible tablets .........8 Bleomycin 15,000I.U. injection ...................... 5 Fentanyl (Abstral) 800microgram sublingual tablets ............................................................8 Diazepam (Diazemuls) 10mg/2ml emulsion for injection ................................................... 5 Fluoxetine 10mg tablets ................................8 Human normal Immunoglobulin (IVIg 10%) .. 5 Fluoxetine 30mg capsules ..............................8 Lorazepam 4mg/ml solution for injection ..... 5 Fluoxetine 40mg capsules ..............................9 Mitomycin 2mg and 10mg powder for Haloperidol 5mg/5ml oral solution sugar free solution for injection/infusion ....................... 5 .......................................................................9 Phenobarbital 30mg/ml solution for injection Histamine (H2) antagonists............................9 ....................................................................... 6 Hormone Replacement Therapy products Ranitidine 50mg/2ml injection ...................... 6 (HRT) ........................................................... 10 Somatropin 200microgram MiniQuick Irbesartan 150 mg/hydrochlorothiazide 12.5 (Genotropin) device ....................................... 6 mg (CoAprovel) tablets ............................... 10 1 COMMERCIAL-SENSITIVE Isosorbide mononitrate (Isotard) 50mg Ciprofloxacin (Ciproxin) 100mg/50ml solution modified release tablets .............................. 10 for infusion (Bayer) ..................................... 14 Isosorbide Mononitrate (Imdur) 60mg Coal tar (Psoriderm) emulsion (Dermal) ..... 14 modified release tablets .............................. 11 Desmopressin (DDAVP) 0.01% w/v intranasal Itraconazole 10mg/ml oral suspension ....... 11 solution (Ferring) ........................................ 14 Mianserin 10mg tablets ............................... 11 Efavirenz (Sustiva) 50mg, 100mg & 200mg Moclobemide 150mg and 300mg tablets.... 11 capsules and 600mg tablets (Bristol Myers Squibb) ........................................................ 14 Phenelzine sulphate (Nardil) 15mg tablets . 11 Estradiol hemihydrate (Elleste Solo MX) Phillips' Milk of Magnesia 415mg/5ml 40microgram and 80microgram patches (magnesium hydroxide) oral suspension ..... 11 (Viatris) ........................................................ 15 Pioglitazone 15mg/metformin 850mg Fosamprenavir (Telzir) 50mg/ml oral (Competact) tablets ..................................... 11 suspension (ViiV Healthcare) ...................... 15 Prazosin (Hypovase) 1mg tablets ................ 12 Gabapentin 400mg capsules (Tillomed) ..... 15 Promethazine 25mg tablets ........................ 12 Lacidipine 2mg tablets (Teva) ..................... 15 Ranitidine oral preparations ........................ 12 Losartan 100mg / Hydrochlorothiazide Rifampicin 300mg/isoniazid 150mg (Rifinah) 12.5mg tablets (Teva) ................................. 15 tablets .......................................................... 12 Methadone (Physeptone) 5mg tablets Tapentadol (Palexia) 20mg/ml oral solution (Martindale) ................................................ 15 ..................................................................... 12 Mirtazapine 45mg tablets (Teva) ................ 15 Trifluoperazine 1mg/5ml syrup ................... 12 Neomycin 500mg tablets (Advanz Pharma) 15 Tuberculosis medications ............................ 12 Pregabalin 25mg, 50mg and 225mg capsules Voriconazole 40mg/ml powder for oral (Tillomed) .................................................... 16 suspension ................................................... 12 Repaglinide (Prandin) 500microgram, 1mg & Other ................................................................ 13 2mg tablets (Novo Nordisk) ........................ 16 Desmopressin (Desmospray) Sodium bicarbonate 500mg capsules (Teva) 10micrograms/actuation nasal spray .......... 13 .................................................................... 16 Desmopressin (Octim) Tramadol (Zydol) 50mg capsules x 30 pack 150microgram/actuation nasal spray ......... 13 (Grunenthal) ............................................... 16 Fentanyl (Instanyl) 100 microgram and 200 Tramadol 50mg capsules (Teva) ................. 16 microgram nasal sprays ............................... 13 Tramadol 37.5mg / Paracetamol 325mg Fludroxycortide 0.0125% cream .................. 13 tablets (Teva) .............................................. 16 Metronidazole (Acea) 0.75% gel .................. 13 Resolved .............................................................. 17 Vaccines ........................................................... 13 Acetazolamide SR (Diamox SR) 250mg capsules (23/4/21) ...................................... 17 Pneumovax 23 pre-filled syringes ............... 14 Atracurium besilate solution for injection Discontinuations .................................................. 14 vials and ampoules (all strengths) (4/21) ... 17 Alfuzosin (Xatral) 2.5mg tablets (Sanofi) ..... 14 Balneum Bath Additive (4/4/21) ................. 17 Amisulpride (Solian) 100mg/ml oral solution Balneum Plus bath oil (26/4/21) ................. 17 (Sanofi) ......................................................... 14 2 COMMERCIAL-SENSITIVE Cimetidine 200mg/5ml oral solution (sugar Granisetron (Sancuso) 3.1mg/24 hours free) (9/4/21) ............................................... 17 transdermal patches (20/4/21) .................. 17 Crisantaspase (Erwinase) injection (6/4/21)17 Mianserin 30mg tablets (16/4/21).............. 17 Diltiazem (Zemtard) 240mg Capsules (5/5/21) Repaglinide 1mg and 2mg tablets (5/5/21) 17 ..................................................................... 17 Sodium cromoglycate (Intal) 5mg inhaler Dorzolamide (Eydelto) 20mg/mL preservative (5/5/21) ....................................................... 17 free eye drops (16/4/21) ............................. 17 Voriconazole 200mg powder for solution for Enalapril 5mg tablet (15/4/21) .................... 17 infusion (21/4/21) ....................................... 17 Ethinylestradiol 30microgram/drospirenone Zonisamide 25mg capsules (14/4/21) ........ 17 3mg (Yasmin) tablets (10/4/21)................... 17 Zonisamide 50mg capsules (14/4/21) ........ 17 Ethinylestradiol 35 microgram/cyproterone Appendix ............................................................. 18 2mg tablets (Dianette) tablets (22/3/21) .... 17 Table 2: HRT availability and anticipated Ferrous fumarate 322mg/Folic Acid 0.35mg resolution dates .......................................... 18 (Pregaday) tablets (26/4/21) ....................... 17 Information provided: w/c 3 May 2021 New Issues Injectables Calcitonin (salmon) 50units/1ml solution for injection ampoules • Essential Pharma, sole supplier is out of stock until March 2022. • Calcitonin (salmon) 100units/1ml solution for injection ampoules remain available and can support the uplift in demand. Diamorphine 5mg and 10mg injection • There have been intermittent supplies of diamorphine 5mg and 10mg injections