Teaching the History & Social Aspects of Pharmacy
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The Vascular Plants of Massachusetts
The Vascular Plants of Massachusetts: The Vascular Plants of Massachusetts: A County Checklist • First Revision Melissa Dow Cullina, Bryan Connolly, Bruce Sorrie and Paul Somers Somers Bruce Sorrie and Paul Connolly, Bryan Cullina, Melissa Dow Revision • First A County Checklist Plants of Massachusetts: Vascular The A County Checklist First Revision Melissa Dow Cullina, Bryan Connolly, Bruce Sorrie and Paul Somers Massachusetts Natural Heritage & Endangered Species Program Massachusetts Division of Fisheries and Wildlife Natural Heritage & Endangered Species Program The Natural Heritage & Endangered Species Program (NHESP), part of the Massachusetts Division of Fisheries and Wildlife, is one of the programs forming the Natural Heritage network. NHESP is responsible for the conservation and protection of hundreds of species that are not hunted, fished, trapped, or commercially harvested in the state. The Program's highest priority is protecting the 176 species of vertebrate and invertebrate animals and 259 species of native plants that are officially listed as Endangered, Threatened or of Special Concern in Massachusetts. Endangered species conservation in Massachusetts depends on you! A major source of funding for the protection of rare and endangered species comes from voluntary donations on state income tax forms. Contributions go to the Natural Heritage & Endangered Species Fund, which provides a portion of the operating budget for the Natural Heritage & Endangered Species Program. NHESP protects rare species through biological inventory, -
Outline of Angiosperm Phylogeny
Outline of angiosperm phylogeny: orders, families, and representative genera with emphasis on Oregon native plants Priscilla Spears December 2013 The following listing gives an introduction to the phylogenetic classification of the flowering plants that has emerged in recent decades, and which is based on nucleic acid sequences as well as morphological and developmental data. This listing emphasizes temperate families of the Northern Hemisphere and is meant as an overview with examples of Oregon native plants. It includes many exotic genera that are grown in Oregon as ornamentals plus other plants of interest worldwide. The genera that are Oregon natives are printed in a blue font. Genera that are exotics are shown in black, however genera in blue may also contain non-native species. Names separated by a slash are alternatives or else the nomenclature is in flux. When several genera have the same common name, the names are separated by commas. The order of the family names is from the linear listing of families in the APG III report. For further information, see the references on the last page. Basal Angiosperms (ANITA grade) Amborellales Amborellaceae, sole family, the earliest branch of flowering plants, a shrub native to New Caledonia – Amborella Nymphaeales Hydatellaceae – aquatics from Australasia, previously classified as a grass Cabombaceae (water shield – Brasenia, fanwort – Cabomba) Nymphaeaceae (water lilies – Nymphaea; pond lilies – Nuphar) Austrobaileyales Schisandraceae (wild sarsaparilla, star vine – Schisandra; Japanese -
Evaluation on the Effects of Hydrocolloids on Sensory, Texture and Color Properties of Mulberry Pastille
242 October, 2019 AgricEngInt: CIGR Journal Open access at http://www.cigrjournal.org Vol. 21, No. 3 Evaluation on the effects of hydrocolloids on sensory, texture and color properties of mulberry pastille Nosrat Azimi1, Shadi Basiri2*, Ali Mortazavi3 (1. MSc of Food Science and Technology, Sabzevar Branch, Islamic Azad University; 2. Assistant professor, Agricultural Engineering Research Department , Khorasan Razavi Agricultural and Natural Resources Research Center, AREEO, Mashhad, Iran; 3. Professor, Food Science and Technology Department, Faculty of Agriculture, Ferdowsi University of Mashhad, Iran) Abstract: White mulberry is a fruit with high nutritional quality. The shelf life of Mulberry is short due to high moisture content. In this research, a new product from white Mulberry called pastille was formulated. Two hydrocolloid ingredients: guar (0%, 0.5% and 1%) and gelatin (0%, 1% and 2%) were used for pastille formulations. Parameters such as color parameters (L* a* b*), sensory evaluations and texture profile analysis (TPA) of samples were investigated. The results of texture evaluation showed that springiness, chewiness, adhesiveness and hardness increased by increasing gelatin, while cohesiveness decreased. Hardness and adhesiveness decreased by addition of the guar. Hardness and adhesiveness decreased with adding guar. Sensory evaluation showed that increasing of the hydrocolloids led to the decrease of acceptability scores. The parameters of a* and b* of pastille samples increased with increasing hydrocolloids concentration, however L* values decreased when the amount of hydrocolloids increased. Mulberry pastille including 1% guar and 1% gelatin having the lowest amount of hardness, adhesiveness, chewiness and suitable color characteristics, was determined as the best formulation among the other investigated samples. -
Celebrating the Rich History of Waxes Bladel, the Netherlands What’S Inside: Watertown, Connecticut, Usa
CELEBRATING THE RICH HISTORY OF WAXES BLADEL, THE NETHERLANDS WHAT’S INSIDE: WATERTOWN, CONNECTICUT, USA 2-3 – HERITAGE 4-5 – INNOVATION 6-7 – WORLD RESOURCES 8-9 – NATURAL/ORGANIC 10-11 – SILICONYL WAXES 12-13 – CUSTOM BLENDS 14-15 – EMULSIFYING WAXES 16-17 – KESTER WAXES 18-19 – MILKS 20-41 – WAX SPECIFICATIONS 42 – WAX PROPERTIES KOSTER WAX FACT: Koster Keunen was founded in the Netherlands and is world renowned for supplying quality waxes. 1852 OUR HISTORY OF TRADITION AND INNOVATION Founded in 1852 as a family business, Koster Keunen has evolved into the world’s leading processor, refiner and marketer of natural waxes. From the early days of sun bleaching beeswax for the candle industry, we now specialize in processing and formulating quality waxes for cosmetics, pharmaceutical, food, coatings, and various other technical industries worldwide. For over 150 years we have sought perfection, constantly introducing new and innovative processes and waxes, while investing in experienced, knowledgeable people and the best equipment to help meet this goal. As a family business we believe very strongly in the need for developing 3 superior quality products, and supporting our customers with excellent service, throughout the formulation and marketing processes. From our two facilities, in the USA and Holland, we offer a huge range of natural waxes, synthetic waxes and wax derivatives, enabling our customers to produce thousands of products that look, feel and work superbly KOSTERKEUNEN.COM / 1 860.945.3333 KOSTER WAX FACT: Koster Keunen was the first natural wax company to manufacture waxes using a Sandvik Pastillator, starting in 1988. 1852 UNIQUELY KOSTER KEUNEN Our greatest strength is the experience and scientific expertise we have fostered for the development of new and innovative products. -
API & Dosage Form Development
API and Dosage Development W I T H D A LT O N Peter Pekos [ C O M P A N Y V I S I O N ] "To make the impossible possible. Dalton Pharma Services uses its scientific and pharmaceutical expertise to bring customer ideas to life. We develop their new drug products, optimize the synthesis of therapeutic candidates, and manufacture them at the highest level of quality." [ S E R V I C E S ] Contract Research Custom Synthesis Medicinal and Flow Chemistry API Process Development Formulation Development cGMP API Manufacturing cGMP Sterile Filling Analytical and Microbiology Services FDA inspected, HC approved, & MRA with EMA API Form Development API Definition Active pharmaceutical ingredient (API) – the substance(s) in pharmaceutical drugs that is/are responsible for the beneficial health effects experienced by consumers. (1) API Selection Key factors that drive API selection (2): Crystallinity: Influences the dissolution rate and transport characteristics of the drug (3) Polymorphism: The ability of a drug substance to Solubility: take on more than one form/ The ability of a solute to dissolve in crystalline phase. Influences drug solvent. Influences desired dissolution and drug stability (i.e., concentration and drug premature degradation) (4) absorption (6) Density: Influences flow properties and Stability: compressibility (5) Influenced by moisture, excipients, temperature, pH, oxygen, light (7) Particle size distribution: Influences the ability of the drug to Density: cross blood barriers, enter cells, Influences flow properties and and absorbed by the human body compressibility (5) (2) The development stage and needs API & CTD Note: In any clinical application or new drug submission the 1) description of manufacturing (including flowcharts) is required along with 2) physiochemical characteristics (melting point, boiling point, denaturation temperature, solubility) (2.3.S.2, 2.3.S.3 and 2.3.P.3) (4) Once the API form is determined, the dosage form must be selected. -
Novel Dry Powder Inhaler Formulation Containing Antibiotic Using Combined Technology to Improve Aerodynamic Properties
Novel dry powder inhaler formulation containing antibiotic using combined technology to improve aerodynamic properties Rita Ambrus 1* , Edit Benke 1, Árpád Farkas 2, Imre Balásházy 2, Piroska Szabó-Révész 1 1Faculty of Pharmacy, Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Szeged, Hungary 2Centre for Energy Research, Hungarian Academy of Sciences, Budapest, Hungary *Corresponding author: [email protected] Abstract Dry Powder Inhaler (DPI) could offer a propellant-free, easy-to-use powder form ensuring better stability than liquid dosage forms. Therefore the development of traditional carrier-based and carrier-free new generation systems is a determinative factor in the field of DPI formulation. The purpose of our research work was to combine these two systems, utilizing their beneficial properties to produce a novel pulmonary drug delivery system containing ciprofloxacin hydrochloride (CIP). Co-spray drying, surface smoothing and the preparation of an interactive physical mixture were applied as the technological procedures of sample preparation. The carrier-based and carrier-free formulations, as well as the developed novel product were compared to each other. Structural investigations were made by X-ray powder diffraction and micrometric properties (habit, bulk density) were determined. Particle interactions were also evaluated to investigate surface free energy, cohesive-adhesive forces, and spreading coefficient. In vitro aerodynamic properties (mass median aerodynamic diameter, fine particle fraction (FPF) and emitted dose of DPIs were measured using Andersen Cascade Impactor. A novel in silico Stochastic Lung Model was also used to quantify the amount of particles deposited at the target area. The novel-formulated composition presented amorphous spherical particles with an average size of about 2 µm. -
Randomised, Double-Blind, Placebo-Controlled Study of A
J Pharm Pharmaceut Sci (www.cspsCanada.org) 15(2) 281 - 294, 2012 Randomised, Double-Blind, Placebo-Controlled Study of a Single Dose of an Amylmetacresol/2,4-dichlorobenzyl Alcohol Plus Lidocaine Lozenge or a Hexylresorcinol Lozenge for the Treatment of Acute Sore Throat Due to Upper Respiratory Tract Infection Damien McNally,1 Adrian Shephard,2 Emma Field3 1 Ormeau Health Centre, Belfast, UK; 2 Professional Relations, Reckitt Benckiser, Slough, UK; 3 Global Medical Affairs, Reckitt Benckiser Healthcare, Hull, UK. Received, January 31, 2012; Revised, February 24, 2012; Accepted, April 1, 2012; Published, April 2, 2012. ABSTRACT - Purpose: Sore throat is a frequent reason for seeking medical care but few prescription options are available. Lozenges are effective in delivering active ingredients to the throat. This study was conducted to determine the analgesic efficacy of two lozenges one containing amylmetacresol (AMC)/2,4- dichlorobenzyl alcohol (DCBA) and lidocaine and one containing hexylresorcinol versus placebo in patients with acute sore throat due to upper respiratory tract infection (URTI). Methods: This was a multicentre, randomised, double-blind, parallel group, placebo-controlled study. In total, 190 patients were randomised 1:1:1 to a single dose of AMC/DCBA + lidocaine, hexylresorcinol or placebo lozenge. Subjective ratings of throat soreness, difficulty swallowing, swollen throat, numbing, and sore throat relief were obtained up to 2 hours post dose. Patient and investigator global ratings and a consumer questionnaire -
Inula Helenium: a Literature Review on Ethnomedical Uses, Bioactive Compounds and Pharmacological Activities
Lucrări Ştiinţifice Seria Medicină Veterinară, 63 (1) / 2020, USAMV Iaşi Inula helenium : A literature review on ethnomedical uses, bioactive compounds and pharmacological activities Victoria BUZA *1 , Maria-Cătălina MATEI 1, Laura Cristina ȘTEFĂNUȚ 1 1 University of Agricultural Sciences and Veterinary Medicine, Faculty of Veterinary Medicine, Department of Preclinical Sciences, 3-5 Mănăștur Street, Cluj-Napoca, Romania e-mail: [email protected] Abstract Dynamic growth of antimicrobial and anthelmintic resistance throughout the years has caused increased interest in natural alternatives to synthetic drugs. Elecampane (Inula helenium L.), a widely distributed herbaceous plant, is one of the most researched and well-known member of the genus Inula, family Compositae. I. helenium has been included in the Chinese Pharmacopeia, Russian Pharmacopeia and Pharmacopeias of some European countries. This review is an up-to-date summary of the existing knowledge on Inula helenium’s ethnomedicinal uses, secondary metabolites and pharmacological activities. Initially used in the treatment of respiratory and digestive diseases in both humans and animals, the roots of elecampane have been also proven to possess a cytotoxic and antiproliferative effect on cancer cell lines, as well as anti-inflammatory, antioxidant, antibacterial, antifungal and anthelmintic activities. The main bioactive compounds isolated from elecampane roots known to be responsible for their pharmacological activities are inulin, sesquiterpene lactones such as alantolactone and isoalantolactone, thymol derivatives, phenolic acids and flavonoids. This review suggests that I. helenium’s secondary metabolites have a strong therapeutic potential. However, further in vitro and in vivo studies of isolated I. helenium bioactive compounds are required in order to understand their mechanism of action, pharmacokinetics and potential adverse effects. -
Manufacture and Characteristics of Pastilles and Their Coating by Crystallization Process
MANUFACTURE AND CHARACTERISTICS OF PASTILLES AND THEIR COATING BY CRYSTALLIZATION PROCESS DISSERTATION zur Erlangung des akademischen Grades Doktor-Ingenieur (Dr.-Ing.) genehmigt durch die Mathematisch-Naturwissenschaftlich-Technische Fakultät (Ingenieurwissenschaftlicher Bereich) der Martin-Luther-Universität Halle-Wittenberg von Herrn M.Sc. Jung-Woo Kim geb. am 20.08.1972 in KyoungNam / Süd Korea Dekan der Fakultät: Prof. Dr. Ludwig Staiger Gutachter: 1. Prof. Dr. -Ing. habil. Joachim Ulrich 2. Prof. Dr. habil. Karsten Mäder 3. Dr. -Ing. Ulrich Teipel Halle (Saale), den 15. 12. 2003 urn:nbn:de:gbv:3-000006229 [http://nbn-resolving.de/urn/resolver.pl?urn=nbn%3Ade%3Agbv%3A3-000006229] CONTENTS CONTENTS 1. INTRODUCTION ……………………………………………......…………... 1 2. TECHNICAL BACKGROUND AND THEORY ………………………….. 3 2.1. Melt solidification ……………………………………………………..... 3 2.1.1. Technical background of melt solidification processes ………..…. 3 2.1.2. Approximation of crystallization rate ………………………..…… 5 2.1.3. Degree of deformation ………………………………………..…... 5 2.2. Porosity ……………………………………………………………..…... 7 2.3. Nucleation and crystal growth in solution …………………………..….. 11 2.3.1. Nucleation ……………………………………………………..….. 11 2.3.1.1. Types of nucleation …………………………………..……... 11 2.3.1.2. Kinetic of nucleation …………………………………..……. 12 2.3.1.3. Surface nucleation ……………………………………..……. 14 2.3.2. Growth rate …………………………………………………..…… 16 2.3.2.1. Theory of crystal growth ………………………………..…... 16 2.3.2.2. Kinetic of crystal growth ………………………………..…... 17 2.4. Agglomeration mechanism ………………………………………...…….. 19 2.5. Interfacial tension …………………………………………………..……. 21 2.6. Seeding technology ………………………………………………..…….. 23 3. STATE OF ART AND OBJECTIVES OF THESIS ………………....…….. 24 3.1. State of art …………………………………………………………..…... 24 3.1.1. Crystallization time of drops ………………………………..…….. 24 3.1.2. Coating mechanism in a crystallization process ……………..…… 25 3.1.2.1. -
Best Prices in Europe!
Best Prices in Europe! 2013 6.Edition 2016 Bonbons Page 3-13 Caramels Page 14 Chocos Page15-22 Gum Page 23 Ice Page 24 Lollipops Page 25-32 Mints Page 33-34 Pastilles Page 35 Fruits & Nuts Page 36-41 Page 2 Bonbon All Natural Genuine handmade sweets without E-numbers, artificial colouring or flavouring – based on natural ingredients only. Choose from many delicious flavours, with or without filling. The sweets are wrapped in 100% bio- degradable cellophane. Facts Bonbon All Natural Type Double twist sweet Shape Oval 100% natural sweets, no artificial additives, Quality pure fruit only Net weight 5 g Filled: Choco/mint, Strawberry/cream, Hazelnut/cream, Lemon Lime, Strawberry/ fruit, Raspberry/fruit, Blood Orange, Apple, Liquorice/aniseed, Mixed Bonbons (Choco/ mint, Hazelnut/cream, Lemon Lime, Flavours Strawberry/fruit, Blood Orange, Liquorice/ aniseed) Unfilled: Lemon Lime, Liquorice, Eucalyptus, MixedFruits (Lemon Lime, Raspberry, Apple, Orange, Ice-mint) Flavours can be mixed, minimum 30 kgs Mix per flavour Delivery time 15 working days ex works Minimum 12 months from the date of Shelf-life production Store in a dark and dry location at a Storage temperature of 13-18°C Foil 100% biodegradable cellophane made Quality from Swedish wood pulp Dimensions (LxW) 60 mm x 89 mm incl. closure Colour White Full width printing: 87-88 mm. Logo in the Advertising surface centre max width: 30 mm Printing 1-4 Pantone Shipping Minimum order 30 kgs (approx. 6.000 sweets) Inner packing 5 kgs in bulk per box Page 3 Bonbon All Natural Gold / Silver Genuine handmade sweets without E-numbers, wrapped in silver or gold foil, artificial colouring or flavouring – based on natural ingredients only. -
Field Checklist
14 September 2020 Cystopteridaceae (Bladder Ferns) __ Cystopteris bulbifera Bulblet Bladder Fern FIELD CHECKLIST OF VASCULAR PLANTS OF THE KOFFLER SCIENTIFIC __ Cystopteris fragilis Fragile Fern RESERVE AT JOKERS HILL __ Gymnocarpium dryopteris CoMMon Oak Fern King Township, Regional Municipality of York, Ontario (second edition) Aspleniaceae (Spleenworts) __ Asplenium platyneuron Ebony Spleenwort Tubba Babar, C. Sean Blaney, and Peter M. Kotanen* Onocleaceae (SensitiVe Ferns) 1Department of Ecology & Evolutionary Biology 2Atlantic Canada Conservation Data __ Matteuccia struthiopteris Ostrich Fern University of Toronto Mississauga Centre, P.O. Box 6416, Sackville NB, __ Onoclea sensibilis SensitiVe Fern 3359 Mississauga Road, Mississauga, ON Canada E4L 1G6 Canada L5L 1C6 Athyriaceae (Lady Ferns) __ Deparia acrostichoides SilVery Spleenwort *Correspondence author. e-mail: [email protected] Thelypteridaceae (Marsh Ferns) The first edition of this list Was compiled by C. Sean Blaney and Was published as an __ Parathelypteris noveboracensis New York Fern appendix to his M.Sc. thesis (Blaney C.S. 1999. Seed bank dynamics of native and exotic __ Phegopteris connectilis Northern Beech Fern plants in open uplands of southern Ontario. University of Toronto. __ Thelypteris palustris Marsh Fern https://tspace.library.utoronto.ca/handle/1807/14382/). It subsequently Was formatted for the web by P.M. Kotanen and made available on the Koffler Scientific Reserve Website Dryopteridaceae (Wood Ferns) (http://ksr.utoronto.ca/), Where it Was revised periodically to reflect additions and taxonomic __ Athyrium filix-femina CoMMon Lady Fern changes. This second edition represents a major revision reflecting recent phylogenetic __ Dryopteris ×boottii Boott's Wood Fern and nomenclatural changes and adding additional species; it will be updated periodically. -
Novel Amphiphilic Block Copolymers and Their Self-Assembled Injectable Hydrogels for Gene Delivery" (2007)
Iowa State University Capstones, Theses and Retrospective Theses and Dissertations Dissertations 2007 Novel amphiphilic block copolymers and their self- assembled injectable hydrogels for gene delivery Ankit Agarwal Iowa State University Follow this and additional works at: https://lib.dr.iastate.edu/rtd Part of the Cell Biology Commons, and the Chemical Engineering Commons Recommended Citation Agarwal, Ankit, "Novel amphiphilic block copolymers and their self-assembled injectable hydrogels for gene delivery" (2007). Retrospective Theses and Dissertations. 15544. https://lib.dr.iastate.edu/rtd/15544 This Dissertation is brought to you for free and open access by the Iowa State University Capstones, Theses and Dissertations at Iowa State University Digital Repository. It has been accepted for inclusion in Retrospective Theses and Dissertations by an authorized administrator of Iowa State University Digital Repository. For more information, please contact [email protected]. Novel amphiphilic block copolymers and their self-assembled injectable hydrogels for gene delivery by Ankit Agarwal A dissertation submitted to the graduate faculty in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Major: Chemical and Biological Engineering Program of Study Committee: Surya K Mallapragada, Major Professor Balaji Narasimhan Jacqueline V Shanks Marit Nilsen-Hamilton Michael J. Wannemuehler Iowa State University Ames, Iowa 2007 Copyright © Ankit Agarwal, 2007. All rights reserved. UMI Number: 3283092 UMI Microform 3283092