DECLARATION FOR HEALTH SCIENCES GRADUANDS

AT THE TIME OF BEING ADMITTED AS A MEMBER OF THE HEALTH PROFESSION:

I solemnly pledge to serve humanity

My most important considerations will be the health of patients and the health of their communities

I will not permit considerations of age, gender, race, religion, ethnic origin, sexual orientation, disease, disability or any other factor to adversely affect the care I give to patients

I will uphold human rights and civil liberties to advance health, even under threat

I will engage patients and colleagues as partners in healthcare

I will practise my profession with conscience and dignity

I will respect the confidentiality of patients, present or past, living or deceased

I will value research and will be guided in its conduct by the highest ethical standards

I commit myself to lifelong learning

I make these promises solemnly, freely and upon my honour.

12 13 FACULTIES OF ENGINEERING & THE BUILT ENVIRONMENT, HEALTH SCIENCES AND SCIENCE

ORDER OF PROCEEDINGS

Academic Procession. (The congregation is requested to stand as the procession enters the hall and is invited to participate in the singing of Gaudeamus)

The Vice-Chancellor will constitute the congregation.

The National Anthem.

The University Dedication will be read by a representative of the SRC.

Musical Item.

Welcome by the Deputy Vice-Chancellor, Professor S Klopper.

Professor Klopper will introduce the guest speaker, Derek Hanekom MP, Minister of Science & Technology.

Address by Derek Hanekom.

The graduands and diplomates will be presented to the Vice-Chancellor by the Deans of the faculties.

The Vice-Chancellor will congratulate the new graduates and diplomates.

Professor Klopper will make closing announcements and invite the congregation to stand.

The Vice-Chancellor will dissolve the congregation.

The procession, including the new graduates and diplomates, will leave the hall. (The congregation is requested to remain standing until the procession has left the hall)

12 13 NAMES OF POSTGRADUATE DIPLOMA 2. FACULTY OF ENGINEERING AND GRADUANDS/DIPLOMATES IN NURSING THE BUILT ENVIRONMENT Dean: Professor F W Petersen *Lorraine Susan Bosch An asterisk * denotes that the degree or Madelie Ruby Crous diploma will be awarded in the absence of Shamiela January POSTGRADUATE DIPLOMA the candidate. Vuyelwa Kili IN ENGINEERING *Zoleka Monica Mahlanyana *Nodathini Cecilia Nkalai In Water Quality Engineering: *Nomonde Australia Tshayingwe *Raymond Joseph Swarts 1. FACULTY OF HEALTH SCIENCES

Acting Dean: Professor S Kidson POSTGRADUATE DIPLOMA IN POSTGRADUATE DIPLOMA OCCUPATIONAL HEALTH IN PROJECT MANAGEMENT

Before presenting the graduands, the Dean *Vernon Jacques Julius *David Michael Peinke will invite all graduating students in the *Sundesh Kripanath Maharaj Faculty to stand and to make the Faculty Declaration (see page 12). All members of DEGREE OF BACHELOR the congregation who treat or will be treat- OF ARCHITECTURAL STUDIES ing patients are invited to join in POSTGRADUATE DIPLOMA affirming or re-affirming their commit- IN PALLIATIVE MEDICINE Catharina Nina Malan ment to ethical patient care. Mokhele Ntho *Bongiwe Mbambisa Sipamla Jean Sebastian Rolando

POSTGRADUATE DIPLOMA IN HEALTHCARE TECHNOLOGY POSTGRADUATE DIPLOMA DEGREE OF BACHELOR OF SCIENCE MANAGEMENT IN PAEDIATRIC RADIOLOGY IN CONSTRUCTION STUDIES

Sthandile Charity Khuzwayo *Tanyia Pillay Deepshika Beeknoo *Nqabisa Mahola Thareefa Mahed *Lungelo Manyathi Afzal Razack Mzuyanda Mbangata *(With distinction) Geoffrey Duncan POSTGRADUATE DIPLOMA Rendall IN PESTICIDE RISK MANAGEMENT *Dean Peter Stockwell DEGREE OF BACHELOR OF Ziyanda Zigayi *Tonny Harris Maulana SCIENCE IN ENGINEERING *Emmanuel Nkosinathi Zondo *Collen Mbereki *Lucky Yabe In Chemical Engineering: Keneuoe Letsela Lebogang Maishe Mahlare POSTGRADUATE DIPLOMA IN *Msawayo Bernard Pereira HEALTH MANAGEMENT

*Perpetual Chikobvu In Civil Engineering: Francois Pierre de Villiers *(With honours) Joanna Clare Boyle (With distinction) Jacques Donovan Theo *Mwamba Nalaluke Kanyonga Hendricks Chinju Pius (With distinction) Hlengiwe Admarah *(With honours) Richard Drummond Hlela Stewart Kelvin Arthur Johnson Bridget Nicolette Maclou (With distinction) Mariaan Malherbe In Electrical Engineering: (With distinction) Wena Marais Ntokozo Sonke Dlamini Pogisho Samuel Matthews Thabang Mabeta Keneilwe Cynthia Modise Rofhiwa Ndou Cheryl Nelson Nomkhosi Lungile Phakathi

14 In Electrical & Computer Engineering: Doctor Alex Mapane 4. FACULTY OF HEALTH SCIENCES Jason Andrew Esselaar Rimbilana Ribbon Masinge Buchule Mbobo Acting Dean: Professor S Kidson *Caitlin Alexandra Melidonis In Electro-Mechanical Engineering: Luyanda Mhlauli Lehlogonolo Makgotlane Phogole James Barlow Mills DEGREE OF BACHELOR OF Matete Kevin Thakaso Thulisa Mkatazo SCIENCE IN AUDIOLOGY *Thandani Mlambo Evelyn Tetelo Moabelo *Lwazi Knowledge Mnguni In Mechanical Engineering: Rylan James Morrison Nonkululeko Mtolo Kerry-Anne Airey Zimasa Mpemnyama Nkululeko Humphrey Cele Sibongiseni Mrwashu Steven Edward Dickinson Cameron Philip Nagel Ameerud-Deen Larney Mxolisi Ndlovu DEGREE OF BACHELOR Nabil Mohamed Nonkosazana Patricia Nkosi OF SCIENCE IN PHYSIOTHERAPY Titus Nampala Sinelizwi Nkwali Anga Ngalo Nuriyah Noordien Nasheetoh Gierdien Potjo Simon Nthama Pholile Gladness Ntshangase *Kushav Romalall Manuel Macangelo Ngombo Sebastiao Jonathan Dominique van Belle DEGREE OF BACHELOR OF SCIENCE DEGREE OF BACHELOR OF (with distinction in Mathematics and the IN MEDICINE (HONOURS) SCIENCE IN GEOMATICS degree with distinction) Shan Weeber In Infectious Diseases & Immunology: *Sebei Timothy Nchabeleng Nosipho Ntombani Zwane *(First class) Valmy Craffert *Jonathan Carey Rush Ata Thabo Mokoena

In Biology, Earth & Environmental Sciences: In Physiology: DEGREE OF BACHELOR OF SCIENCE Jaryd Robert Ernest Davies (First class) Jacob Robin Hoffman IN PROPERTY STUDIES *Siyawamkela Nicholas Sthunda

Marc Mitchell Duckitt *Nicholas Steven Kieswetter In Chemical, Molecular & Cellular Sciences: 5. FACULTY OF SCIENCE Steven James Human Andile Aubrey Khari Dean: Professor A Le Roex *Sidwell Maphangela 3. FACULTY OF SCIENCE Mzameni Shangase DEGREE OF BACHELOR Dean: Professor A Le Roex OF SCIENCE (HONOURS) In Information Technology: Nyameko Mateke In Mathematics: DEGREE OF BACHELOR OF SCIENCE Ts’Eliso Monaheng Brett le Roux Kabelo Rametse Faika Solomon Shabirah Abdullah Hamisi Ratshilele Ravhengani (First class) Michael Blyth Toms Denford Nyasha Banga Tiyani Cecilia Rikhotso Eve-Lyn Mary van Schoor Craig Xavier Basson Merciful Sundlana Rachel Begbie Jason John Bissict Talya Davidoff In Mathematical, Physical & Statistical Tessa Doe de Kock Sciences: Lua Bahhiyyih Dibble Serinah Bukreedan Efensio Eduardo Diogo Menako Sophia Jobo *Isaline Diane Goemaere Athi Rwexu Ragmah Hendricks Michell Anne House Zintle Sharon Kolo Thabo Elias Makgoale Phaswana Mokebe Malatjie Eliab Dikotse Malefahlo

15 6. FACULTY OF ENGINEERING DEGREE OF MASTER OF CITY DEGREE OF MASTER OF AND THE BUILT ENVIRONMENT AND REGIONAL PLANNING SCIENCE IN ENGINEERING

Dean: Professor F W Petersen Elias Jacobus Matthee In Chemical Engineering: A - Aishah Modack Hartmut Dietmar Ortfried Brodner Kudzai Changunda DEGREE OF BACHELOR OF *Mihajlo Dabic ARCHITECTURAL STUDIES Adrian Charles Fortuin (HONOURS) DEGREE OF MASTER *Matthew Raymond Hill OF ENGINEERING Michael Kapembwa *Mogammad Firaas Booley Thendo Madala *Sarah Louis Kuiper In Engineering Management: *Molladi Andrew Maseloane *Tanya Viljoen *Azothiwa Nxasana Kyle Moskovitz Caroline Muzawazi Moses Kumbirai Nduna In Radar & Electronic Defence: *Steve Marc Piaget DEGREE OF BACHELOR OF SCIENCE Saad Ibraheem Alhuwaimel Tawanda Stephen Sango (HONOURS) IN CONSTRUCTION Karthik Shekhar MANAGEMENT Rukaya Ghalib Stracey In Structural Engineering *Jacob Johannes Taute *Simon van Helsdingen & Structural Materials: Eustice Vries *Justine George Kessy *Obinna Kelvin Ukwa In Civil Engineering: DEGREE OF BACHELOR OF SCIENCE *Matteo Angelucci (HONOURS) IN MATERIALS SCIENCE In Transport Studies: Garth Edward Gademan Sivuyile Bebelele Nicholas Magera Kizito *Bridget Gcinaphi Sikhondze *Emmanuel Leo *Hundzukani Vukeya Mbongeni Hopewell Sabelo Nzuza Simon Jon Starck DEGREE OF MASTER Davina Carol Zietsman OF PHILOSOPHY DEGREE OF BACHELOR OF SCIENCE (HONOURS) IN PROPERTY STUDIES In Conservation of the Built Environment: In Electrical Engineering: Nicola Susan Darke John Iyanuoluwa Fadiran Moipone Gertrude Phakisi Brendan Robert Hart Abdul-Aziz Fish Yasmin Mayat Lanche Linden Grootboom Jacobus Philippus van Wyk *Lancelot Jenkin Josiah Chimnanu Jideani DEGREE OF BACHELOR OF Bruce Edward Johnson SCIENCE (HONOURS) In Engineering Education: *Allan Kweli IN QUANTITY SURVEYING Rene Toerien *Ndivhuwo Makondo Christina Matankiso Moerane *Anela Khuthazwa Maya Vusumuzi Moyo In Urban Infrastructure, Stephen Mugisa Design & Management: *Tshina Fa Mulumba *Danilo Alessandro Biccari Phillip Uwizeye Nkubito DEGREE OF MASTER OF *Jacqueline Maria James Shanly Rajan ARCHITECTURE (PROFESSIONAL) Rumbidzayi Dorothy Machiridza *Valentine Siyoi *Lithole Mohase Grant Richard Stowe *James David Goss Theodore Mark Schreuder David Andrew Wright *Jakob Sutter

In Energy Studies: *Jonathan Paul Dingle Olumide Oluwaseun Ogunmodimu

16 In Geomatics: 7. FACULTY OF HEALTH SCIENCES In Radiation Oncology: Patricia Duncan Kellie Rozelle Alleyne-Mike Cleotilda Nxumalo Acting Dean: Professor S Kidson *Moawia Mohammed Ali Elhassan *Khadiga Elfadil Ahmed Mohammed

In Materials Engineering: DEGREE OF MASTER OF FAMILY Khanyisa Prudence Mabunda MEDICINE AND PRIMARY CARE In Radiology: Velile Nicholine Vilane (With distinction in the dissertation) *(With distinction) Anthony Craig Smith Arthur Daire Paul Victor John Scholtz In Mechanical Engineering: Soraya Allies Bradley Denis Bock DEGREE OF MASTER OF MEDICINE James Angus Boonzaier DEGREE OF MASTER OF MEDICINE *Nicholas James Clinning In Anaesthesia: IN EMERGENCY MEDICINE Matthew James Davidson Alexandra Dresner Travis Foster Henchie Mohammed Alshehri Thomas Edward Knight *Moosa Kalla Wei-Chi Lee In Clinical Pharmacology: David Kababa Lwabona (With distinction in the dissertation) *Christiaan Jan Opperman Karen Cohen *Adam Ozinsky DEGREE OF MASTER *Justin Charles Pead OF PHILOSOPHY Michael Florian Rieger In Emergency Medicine: Bryn John Saunders *(With distinction in the dissertation) In Biokinetics: Cameron Wayne Sharp David Frans Maritz (With distinction in the dissertation) Bradley Mark Springer Ziyaad-Ahmad Parker

In Neurosurgery: In Sustainable Energy Engineering: (With distinction in the dissertation) Peter In Disability Studies: Bryce James McCall Kato Ssenyonga Shanaaz Majiet *Crispin Maeder Thompson

In Emergency Medicine: DEGREE OF MASTER OF SCIENCE IN In Nuclear Medicine: *Ignatius Le Roux Postma PROJECT MANAGEMENT Rachelle Elizabeth Steyn

Warren James Calderwood In Gastroenterology (Medical): Tinashe Chizema In Ophthalmology: *Muhammad Naayil Rajabally Zieyaad Isaacs *Marius Anton Scheepers *Sabueng Naomi Mokoto Gcinulwazi Prince Qamata In Maternal & Child Health: Ziningi Patience Zwane In Orthopaedic Surgery: Elled Mwenyekonde *Ian Michael Koller

In Neonatology: DEGREE OF MASTER OF In Paediatrics: *Yaseen Joolay SCIENCE IN PROPERTY STUDIES *Juli Renate Switala *Abdallah Mbarak Al-Jaidi Yaser *Karla Mari Thomas Benjamin Laurence Day Mpho Ene Mokabiri In Nephrology (Adult): In Psychiatry: *(With distinction in the dissertation) Neil John Yorke Roger John de Andrade Merryn Elizabeth Young

In Paediatric Critical Care: In Public Health Medicine: *Saskia Coetzee Gina Leanne Bernhardt

17 In Paediatric Neurology: In Health Economics: In Paediatrics: *Hani Mohammed Saeed Alkhaldi Funeka Bango *Kate Helene Balme (With distinction) Jane Phiri

In Palliative Medicine: In Pharmacology: Linda Leonora Ganca Veronica Asibi Amlabu Florentina Ureche DEGREE OF MASTER OF Katya Govender *(With distinction) Suzanne Walter SCIENCE IN AUDIOLOGY

Nicola Leigh Keeton In Public Mental Health: DEGREE OF MASTER Tracy McClinton Appollis OF SCIENCE IN NURSING

DEGREE OF MASTER OF Karen Rose Giva In Sports Physiotherapy: SCIENCE IN MEDICINE (With distinction in the dissertation) Christopher Allan In Anatomy: Petra Maass DEGREE OF MASTER OF SCIENCE IN Kerri Ann van der Berg OCCUPATIONAL THERAPY

DEGREE OF MASTER OF Judith May Dirks PHILOSOPHY IN EMERGENCY In Bioinformatics: *Clare Lesley Hubbard MEDICINE *Elinambinina Rajaonarifara Inge Ute Steinhoff

In African Emergency Care: *(With distinction in the dissertation) In Biomedical Engineering: Shadi Mahmood Ebrahim Sammour *Mohammed Yagoub Ibrahim Esmail DEGREE OF MASTER OF *Nielen Christoff Venter SCIENCE IN PHYSIOTHERAPY (With distinction) Miné Cheri Zantow In Clinical Emergency Care: Ruth Elizabeth Siebritz Ian Lucas Howard Willem Stassen In Clinical Science & Immunology: *Andrew David Einhorn *Dunja Mrdjen 8. FACULTY OF SCIENCE DEGREE OF MASTER OF PUBLIC HEALTH In Exercise Science: Dean: Professor A Le Roex (With distinction) Veeraj Goyaram *(With distinction) Federico Andrade Regula Delphine Oliver Rivas DEGREE OF MASTER Joelaine Meryll Chetty OF PHILOSOPHY Valdiela Daries In Medical Biochemistry: (With distinction) Kristen Ann *Aqeela Imamdin In Archaeology: Daskilewicz (With distinction) Boris Vejen Krivochiev *Nicholas Alexander Zachariou *Ann Ford Green *Andani Errol Mulelu (With distinction in the dissertation) Tracy Lynn Kolbe-Alexander In Climate Change & Development: Gaolatlhe Mothoagae In Medical Microbiology: *Leslie Ann Ashburner Vedantha Singh (With distinction) Mischa Minne Kirsten Leigh Nortje In Clinical Research: Kirsty Margaret Robinson Gillian Ann Watermeyer In Medical Physics: Cabral Rosa Wicht *Freedom Mukumbiro Hliziyo

In Epidemiology: In Conservation Biology: *(With distinction) Avital Cassidy In Medicine: *Lea Adel Cohen Hlengani Thozama Mathema (With distinction) Shepherd Christine Wanjiku Njuguna Nhamoyebonde Kimberly Lauren Racow Shahra Sattar Phumelele Regina Trasada

18 In Environmental & In Climate Change & Development: In Ocean & Climate Dynamics: Geographical Science: Steven Alaba Arowolo *Joseph Odhiambo Amollo Michael Chad Fitt *Josiane Gravenor Kirsten Annette du Plessis *Jessica Sarah Kavonic *Francisco Gemo Albino Francisco *Chinedu Innocent Ohanyere Amy Harding-Goodman In Environmental Management: Neil Christopher Malan *John-Paul Richard Crowe *Tsinampoizina Marie Sophie *Benjamin Thomas Gaffney In Computer Science: Randriamahefasoa Samantha Louise Jenner (With distinction) Stefan Asanger Amy Weeber *Stephanie Reynolds Edmundo Bruno Filipe Chissungo *Sarah Elizabeth Yates *Martha Ndeyapeuomagano Kamkuemah (With distinction) Maletsabisa Molapo Lebeko Bernard Nkoebele Poulo In Operational Research: DEGREE OF MASTER OF SCIENCE Cecile Margaret Bezuidenhoudt (With distinction) Jon Matthew Calder In Applied Marine Science In Conservation Biology: (Oceanography): *Kimon de Greef Clousa Francisco Sarmento Chevane (With distinction) Katherine Jane In Physical Oceanography: *Jean Vincent Arnaud Nicolas Forsythe Madoda Brian Khumalo Aluwani Elijah Ramulifho (With distinction) Jessica Diane Greenston Craig Thomas Harding In Physics: In Applied Marine Science (Zoology): Vera Kasmin Liebau *Marius Maximian Hromnik *Dylan Thomas Irion Christine Frances Madden Jessica Louise le Roux Heinz Ortmann Kirsty Alexandra McQuaid Louise Moira Palframan In Zoology: Nurudean Norman Ssempa Koebraa Peters Alistair Wayne Fyfe Ralph Gareth Andrew Watson Carolyn Anna Victoria Sanguinetti *Robert Sebastian Mussgnug *Welly Qwabe *Andrew Peter Russell In Applied Mathematics: In Environmental & Nwamaka Mary-Immaculata Ukomadu (With distinction) Ivajlo Georgiev Donev Geographical Science: *Megan Elizabeth van Zyl *Oliver Silver Cowan (With distinction) Vanessa Monique In Archaeology: Lakay Kerryn Ashleigh Warren *(With distinction) Samantha Rae Lee Pan David Bernard Ogier

In Astrophysics & Space Science: *Hassan Bourhrous In Geology: *Rocco Coppejans Desmond Krummeck Eli Kunwiji Kasai *Getachew Mekonnen Mengistie Toky Herimandimby Randriamampandry In Mathematical Statistics: *Lucy Jane Campbell *Tinashe Daniel Chatora In Botany: Darryn Williams Michelle Claire Malan Rabelani Munyai Robyn Faye Powell In Molecular & Cell Biology: Simon Gareth Broadley Paul Kennedy In Chemistry: *Heinrich Richard Behr Lutete Peguy Khonde In Ocean & Atmosphere Science: Mandla Mabunda Nomkwezane Sanny Kobo (With distinction) Shankari Nair Richard Michael Payne (With distinction) Shakeela Sayed

19 9. FACULTY OF ENGINEERING AND Waldo Coetzee Daramy Vandi Von Kallon THE BUILT ENVIRONMENT Thesis Title: Development of a Thesis Title: Circulation rate modelling of computationally efficient bubble column tumbling mill charge using Positron Dean: Professor F W Petersen simulation approach by way of statistical Emission Particle Tracking (PEPT) bubble micro-flow modelling Daramy Kallon has a BEng(Hons) from the DEGREE OF DOCTOR Waldo Coetzee obtained a Chemical University of Sierra Leone, in Sierra Leone, OF PHILOSOPHY Engineering degree at the University of and an MScTE from the Islamic University Potchefstroom. At UCT he has conducted of Technology, in Bangladesh. He has In Chemical Engineering: postgraduate work in mathematical been studying at UCT in the Chemical Harish Appa modelling, which was upgraded from PhD Engineering Department and the Centre for Thesis Title: Numerical modelling of level. Minerals Research since August 2007. hydrodynamics, gas dispersion and mass Waldo Coetzee’s thesis tackles Daramy Kallon’s thesis transfer in an autoclave one of the identified major intellectual examines the frequency of tumbling charge challenges in fluid flow today, namely circulation (known as circulation rate), Harish Appa has a BSc and an MSc in modelling and simulating hydrodynamics a phenomenon not well understood in Mechanical Engineering from UCT. He in multiphase flow. The approach proposed grinding media mills. This circulation rate started his PhD in 2008 in the Department of starts with the flow structure in the vicinity is often assumed to be constant irrespective Chemical Engineering within the Minerals of a single bubble. Computational Fluid of the mill speeds. Using both qualitative to Metals Research Group, working in Dynamics is used to determine the velocity and quantitative approaches, he finds conjunction with the Centre for Research vector field in the vicinity of the bubble, evidence for the view that the tumbling in Computational and Applied Mechanics and simpler analytical solutions that apply charge circulation rate can have near linear and the Centre for Minerals Research. in the asymptote are used to capture the relationships with parameters typical to Harish Appa’s thesis examines majority of the flow structure even for tumbling mill operations. He develops a hydrodynamics, gas dispersion and mass regions between the asymptote. A linear mechanistic model of circulation rate using transfer in an autoclave. Autoclaves are combination of these analytical solutions experimental data derived from a nuclear widely used in mining industry leaching and a proposed statistical model is then imaging technique, Positron Emission circuits for the extraction of base metals. used to develop an extremely high accuracy Particle Track. He further develops a Leach kinetics may be limited by the gas- estimate of the bubble local flow structure scheme for visualising the distribution of liquid mass transfer which is controlled at a particular Reynolds number, which energy in the grinding environment using by hydrodynamics and gas dispersion summarises the velocity, bubble size, fluid continuum ideas. This scheme delineates in the autoclave. For his doctoral study, density and viscosity. The parameters are the energy in the grinding environment into Harish developed a Computational then cross-correlated with the Reynold’s aspects of breakage, heat and other energy Fluid Dynamics (CFD) model of a pilot- number such that the entire flow structure losses. scale autoclave and validated this with can be replicated via an algebraic function. experimental data, including detailed As such, the simulation which, when Supervisor: Dr I Govender fluid flow data obtained by Particle Image applying traditional techniques, would (Department of Physics) Velocimetry. The CFD model predicts fluid take up to an hour to complete, can be Co-supervisor: A/Professor AN Mainza flow, gas dispersion and mass transfer in concluded within micro-seconds. This (Chemical Engineering) the vessel. The model revealed atypical bubble-cell model is embedded into a flow behaviour which had an adverse effect macro-model which can then simulate on gas dispersion, resulting in poor mass large-scale multiphase flow in a fraction In Civil Engineering: transfer in the autoclave. The outcomes of of the time taken to simulate by other Kirsty Jane Carden this study are of fundamental interest to the means. It has further been shown that the Thesis Title: A measure of sustainability in mining industry as the CFD model may be model can be used to predict mass and heat the context of urban water management in used to develop more efficient industrial transfer coefficients, and also to optimise South Africa autoclaves. bubble column designs. Kirsty Carden has a BSc and an MSc Supervisor: Professor D Deglon Supervisor: Dr R Rawatlal (Applied Science in Civil Engineering) (Chemical Engineering) (Chemical Engineering) from UCT. She has been a member of the Co-supervisor: Professor C Meyer Urban Water Management group in the (Mechanical Engineering, Civil Engineering Department at UCT Stellenbosch University) since 2004, when she commenced her MSc studies. While completing her postgraduate studies she has contributed to, and helped to manage, a number of research projects. This included assistance with the supervision of several BSc(Eng) and MSc students. Kirsty Carden’s PhD research focuses on creating an understanding of

20 sustainability in a South African urban The methodology applied in this study can In Energy Studies: water context using a systems approach. also be a useful decision making tool for Ernest Mazimpaka A framework for sustainability in the SA identification of preferences and isolating Thesis Title: Woodfuel in Rwanda: impact water sector was developed and this was customer segments in the water and on energy, poverty and the environment used to identify suitable indicators for the sanitation sector. assessment process – preferably linked to Ernest Mazimpaka has a BSc in Physics existing measurement initiatives in the SA Supervisor: A/Professor R Del Mistro from the National University of Rwanda water sector. This led to the development (Civil Engineering) and an MSc in Renewable Energy from the of a composite index, the “Sustainability University of Oldenburg in Germany. He Index for Integrated Urban Water has been studying at UCT, in the Energy Management” (SIUWM) which provides In Electrical Engineering: Research Centre, since 2006. a summary analysis of the factors that Nadarajan Moodley Ernest Mazimpaka’s thesis make for sustainability within the urban Thesis Title: Power transformer health examines how the current woodfuel water sector. The index can be used as an assessment derived from low energy and industry impacts on energy, poverty and advocacy tool to encourage institutional dissolved parameters forests in Rwanda. He analyses woodfuel and political support for improved delivery. production, demand, supply and use It was used to measure the current situation Nadarajan Moodley is a Professional and and looks at their legal and regulatory pertaining to the nine member cities of the Certificated Engineer with Bachelor of framework. He answers the question of South African Cities Network. Engineering, Bachelor of Commerce and how far policy instruments are supporting Master’s in Business Leadership degrees. sustainable management and whether Supervisor: A/Professor NP Armitage He has been studying at UCT on a part time they increase, or alleviate the pressure (Civil Engineering) basis while employed as a Chief Engineer on woodfuel resources. He finds that at Eskom in Cape Town. considering woodfuel consumption under Nadarajan Moodley’s thesis an only environment or energy perspective Dorothy Kobel examines the effects of low energy resulted in a narrowly environment Thesis Title: Quantifying the value of degradation of the cellulose and oil or energy solution that benefit the non-user benefits of improving water and insulation of power transformers. Using environment and woodfuel supply but sanitation in informal settlements both analytical and empirical techniques, deprive local people of their traditional he conceived a Low Energy Degradation benefits from woodfuel sales. The loss of Dorothy Kobel has a BSc in Civil Triangle to assess and track the degradation income creates a negative attitude towards Engineering from Makerere University in process at lower temperatures than usually the implementation of forest conservation Kampala and an MSc in Municipal Water considered, thus providing an early policies, thereby increasing deforestation. and Infrastructure from UNESCO-IHE detection of a change in transformer health Ernest Mazimpaka’s research recommends in Delft (The Netherlands). She has been from normal to a deteriorating state. The community-based woodfuel production part of the Urban Infrastructure Design Low Energy Degradation Triangle has and forest replenishment associations as and Management programme at UCT since been successfully applied to the generator sustainable management approaches to 2008. During this time she has contributed transformer fleet within Eskom, identifying mobilise community support for sustainable to a number of academic research projects several significant transformers needing forestry management and woodfuel and courses while completing her PhD intense monitoring. The analysis indicates production to benefit all stakeholders. research. that deterioration in several transformers Dorothy Kobel’s thesis commenced as a result of the effects of Supervisor: Dr G Prasad investigates the value among society of the geomagnetic storms initiated by solar (Energy Research Centre) benefits of improving water and sanitation flares. This method can be effectively used in informal settlements. She focuses on as an asset management tool, allowing the cities of Kampala and Cape Town, and for effective decision making to prevent applies a stated preference choice model sudden failures and reduce the downtimes to quantify the benefits that were felt by of the power stations. other members of society when water and sanitation services in informal settlements Supervisor: Professor CT Gaunt were improved. In both case studies, (Electrical Engineering) respondents’ willingness to pay is highest when the informal settlement is located near the respondents’ neighbourhood. The significant components of non-user value are found to be the value associated with the health benefits of reducing diarrhoea and the value associated with environmental benefits of reduced pollution of water courses. The findings of this research can be used to improve the appraisal outcome of informal settlement upgrade projects.

21 10. FACULTY OF DEGREE OF DOCTOR Adijat Omowumi Inyang HEALTH SCIENCES OF PHILOSOPHY Thesis Title: Design and evaluation of a novel meniscal prosthesis for the knee Acting Dean: Professor S Kidson In Biomedical Engineering: Daniel Alejandro Auger Adijat Inyang is a graduate of Obafemi Thesis title: 3D cine DENSE MRI: Awolowo University in Ile-Ife, Nigeria, DEGREE OF DOCTOR OF MEDICINE ventricular segmentation and myocardial having earned a BSc in Metallurgical strain analysis Engineering followed by an MSc in In Medicine: Materials Engineering. She has been Kevin Anthony Michael Daniel Auger graduated from the University studying at UCT, in the Department of Thesis Title: A study of defibrillation of the Witwatersrand with a BSc(Eng) Human Biology and the Medical Imaging waveform, vectors, and diagnostics in Biomedical Engineering in 2007, and Research Unit, since 2008. a BSc(Eng) in Electrical Engineering The meniscus performs vital biomechanical Kevin Anthony Michael has an MBChB in 2009. In 2009 he joined UCT, where functions in the knee joint but when it is from the University of KwaZulu Natal he has been doing research in Magnetic damaged treatment options are limited. (1993), and a Master of Philosophy in Resonance Imaging (MRI) in the MRC/ Adijat Inyang’s thesis addresses this Cardiology from the University of Cape UCT Medical Imaging Research Unit. problem by designing a novel meniscal Town (2007). He trained in internal Daniel Auger’s doctoral research prosthesis possessing mechanical and medicine and cardiology at King Edward focuses on the development of novel tribological properties that are comparable VIII Hospital in Durban (1996-2000) and software algorithms for the analysis and to the native meniscus. Since the natural Groote Schuur Hospital in Cape Town interpretation of data acquired using three- meniscus is composed of a collagen fibre- (2001-2004), respectively. He was admitted dimensional (3D) displacement encoding reinforced composite, she bases her design as a Fellow of the College of Physicians of with stimulated echos (DENSE), which on fibre-reinforced polymeric materials. South Africa in 2001, and was awarded the is an MRI method that is capable of non- Different combinations of composite Certificate in Cardiology of the Colleges of invasively quantifying the 3D motion and materials — silicone and polycarbonate Medicine of South Africa (2004). deformation (strain) of the entire beating urethane reinforced with nylon or Kevin Michael’s thesis that heart in a single scan. He presents a polyethylene fibres — are tested in tension addresses the improvement of implantable method to calculate the strain and quantify and compression. Thereafter a simulation cardioverter defibrillator devices in pigs motion in the right ventricle, achieving study, using finite element analysis of an and people. It shows that percutaneous previously unattainable spatial resolutions. anatomically-based meniscus, is conducted intra-pericardial delivery of defibrillation He also develops and implements a novel to examine the effects of fibre orientation. therapy is feasible and effective. The segmentation algorithm for the entire Finally, a custom-built injection moulding incidence and factors influencing the left ventricle by using properties inherent machine is used to manufacture meniscal burden of inappropriate defibrillation in the DENSE data, reducing the time prostheses which are tested on a friction therapies are evaluated. This work shows required to delineate a single data set by and wear machine that mimics the that defibrillation efficacy may be enhanced 10 fold. Finally, Daniel Auger provides walking cycle. Adijat Inyang shows that by the addition of a monophasic preshock strain mapping algorithms to measure and polycarbonate urethane in combination which may be a programmable option in quantify mechanical dyssynchrony in both with polyethylene fibres provides a good future devices. ventricles. These methods offer a fast and match for the natural meniscus. non-invasive technique for identifying Supervisor: Professor BM Mayosi the anatomical location and assessment of Supervisor: Professor CL Vaughan (Medicine) dysfunction. (Human Biology)

Supervisor: A/Professor EM Meintjes (MRC/UCT Medical Imaging Research In Cell Biology: Unit, Human Biology) Jade Pereira de Andrade Peres Co-supervisor: Dr BS Spottiswoode Thesis Title: The role and regulation of (Cardiovascular MR R&D, Siemens the T-box transcription factor, TBX3, in Healthcare, Chicago, Illinois USA) melanoma progression

Jade Peres obtained a BSc and a BSc(Med)(Hons) at the University of the Witwatersrand, and was awarded a distinction for her work in the subject of Human Anatomy. In 2007 she decided to leave her Alma Mater in order to pursue an MSc and later a PhD in cancer research in the Department of Human Biology at UCT. Jade Peres’s PhD focuses on exploring the role and regulation of the T-box transcription factor, TBX3, in

22 melanoma progression where it was found is associated with reduced protective *Alykhan Vira to be overexpressed. She shows that TBX3 immune responses and impaired killing Thesis Title: Role of M3 muscarinic plays a pivotal role in melanoma formation effector functions of macrophages and receptor in regulation of immunity to and invasion and that silencing it could inflammatory dendritic cells. In summary, infectious pathogens inhibit the aggressive nature of this cancer. Ramona Hurdayal’s thesis shows that IL- Furthermore, she demonstrates that TBX3 4Rα-signalling on dendritic cells plays an Alykhan Vira has a BSc in Biochemistry is overexpressed in melanoma due to post- important role in host protection against and a BSc(Med)(Hons) in Infectious transcriptional regulation by the protein cutaneous Leishmaniasis. Diseases and Immunology from UCT. kinase B (AKT) signalling pathway, and In 2009 he was awarded a fellowship that TBX3 is an important mediator of Supervisor: Professor F Brombacher with the International Center for Genetic AKT-induced cell migration. Finally, she (ICGEB & Clinical Laboratory Sciences: Engineering and Biotechnology (ICGEB) identifies inhibitor of differentiation 1 Immunology) to complete a PhD in Immunology. (ID1) as a direct TBX3 target gene and Co-supervisor: Dr NE Nieuwenhuizen Alykhan Vira’s thesis focuses on elucidates the molecular mechanism by (Clinical Laboratory Sciences: a role for muscarinic receptors in immunity which TBX3 regulates this important Immunology) to infectious pathogens. Acetylcholine is player in melanoma cell migration and the first neurotransmitter discovered and invasion. This work identifies TBX3 signals via two types of receptors, nicotinic as an important prognostic marker and Jaisubash Jayakumar and muscarinic acetylcholine receptors. therapeutic target for melanoma, which has Thesis Title: The role of IL-4 receptor Although primarily known for its role in important implications for the treatment of alpha in chronic allergic airway disease nerve impulse transmission, increasing this highly intractable disease. (AAD) evidence suggests an important role for acetylcholine signaling in regulation of Supervisor: A/Professor S Prince Jaisubash Jayakumar has an MSc from the immune system. Nicotinic receptors (Human Biology) the Bharathiar University, India. He has have been shown to have a strong anti- Co-supervisor: Dr S Mowla been studying at UCT in the Division of inflammatory activity however the role (Human Biology) Immunology’s International Centre for for muscarinic receptor remains unknown. Genetic Engineering and Biotechnology Alykhan Vira’s research, using genetically since 2008. During this time he has engineered mice strains, shows that In Clinical Science & Immunology: presented his novel research findings at muscarinic receptors and particularly Ramona Hurdayal various local and international conferences. the M3 subtype, are required to enhance Thesis Title: Deletion of IL-4 receptor Jaisubash Jayakumar’s thesis immune response to and clearance of alpha on dendritic cells renders BALB/c examines the role of IL-4 receptor alpha, diverse pathogens such as the bacterium mice hypersusceptible to Leishmania the receptor for the cytokine IL-4 and Salmonella typhimurium and the parasitic major infection a molecule known to play a key role in nematode Nippostrongylus brasiliensis. understanding the development of allergic He also identifies CD4 T cells as the main Ramona Hurdayal completed a BSc in asthma. Using two cell-specific knockout immune cell type affected by muscarinic Biological Sciences, followed by Honours mice he investigates the cell specific receptor stimulation. Alykhan Vira’s in Molecular Biotechnology and Master’s in contributions of IL-4Rα signalling in studies suggest that drugs targeting the Biochemistry at the University of KwaZulu the development of Ovalbumin-induced M3 muscarinic receptor, some already in Natal. In 2009, she was awarded a DFG/ chronic allergic airway disease (AAD). In commercial use, may be used to modulate NRF-sponsored fellowship to pursue PhD the first study using IL-4Rα knockout mice the immune response for better outcomes. studies in the Division of Immunology, on CD4+T cells (LckcreIL-4Rα-/lox) he University of Cape Town. Her scientific demonstrates a protective effect where the Supervisor: Professor F Brombacher calibre is reflected in the publication of mice are protected against the development (ICGEB & Clinical Laboratory Sciences: three research papers in peer-reviewed of an allergic phenotype. On the contrary, Immunology) journals and one in revision. in the second study using IL-4Rα knockout Co-supervisor: Dr W Horsnell Ramona Hurdayal’s thesis mice on macrophages and neutrophils (Clinical Laboratory Sciences: investigates the role of IL-4Rα signaling (LysMcreIL-4Rα-/lox) he shows that IL- Immunology) on dendritic cells in a mouse model of 4Rα on IL-4/IL-13 induced alternatively cutaneous Leishmaniasis. Leishmaniasis is activated macrophages (AAM) is not a parasitic infection caused by protozoan essential for the development of AAD parasites of Leishmania species. In her where the mice develop an allergic disease. studies, a transgenic mouse model is The findings of Jaisubash Jayakumar’s established where the IL-4Rα chain was thesis add considerably to the body of deleted on dendritic cells. Following knowledge in understanding the role of infection with Leishmania major, she cytokines in allergic airway diseases. demonstrates that mice lacking IL-4Rα on dendritic cells are hypersusceptible to Supervisor: Professor F Brombacher infection leading to strikingly increased (Clinical Laboratory Sciences) parasite burdens in local and visceral organs. Co-supervisor: Dr N Nieuwenhuizen She further reports that hypersusceptibility (Clinical Laboratory Sciences)

23 In Exercise Science: In Medical Biochemistry: Rajesh Sarkar’s thesis focuses on *Timothy Robert Lindsay Marco Matejcic the association between the strain genotype Thesis Title: Influences on the nonlinear Thesis Title: Identification of genetic of Mycobacterium tuberculosis and in dynamics of human running stride time polymorphisms associated with vitro correlates of virulence, including series oesophageal squamous cell carcinoma growth phenotype and patterns of cytokine risk in South Africa induction in the macrophage model. In Timothy Lindsay has a BSc from Dalhousie addition, his work studies the relationship University and an MSc from University Marco Matejcic completed his schooling in between host genetic background and the of Victoria, both in Canada. He began Rome, and obtained a BSc in Biotechnology innate immune response to different strains studying at the UCT/MRC Research Unit from the University of Rome Tor Vergata. of M. tuberculosis. His findings show that for Exercise Science and Sports Medicine He continued at the same institution, and ‘modern’ clinical M. tuberculosis strains in 2008. During this time he conducted obtained his MSc(Med)(Hons) Medical from South Africa are phenotypically his PhD research and enjoyed running on Biotechnology. He has been studying at diverse with regard to in vitro growth and Table Mountain. (49/50 words) UCT since 2008. cytokine response and that some of these Timothy Lindsay’s thesis Oesophageal squamous cell carcinoma differences are lineage specific. These investigates the system control mechanisms (OSCC) is a complex disorder, determined studies support the notion that clinical exhibited in the timing of human running by the interaction between genetic factors strains of M. tuberculosis may differ in strides. He uses the measurement of the and environmental risk factors. In South virulence and that these differences may time between every stride in a running Africa, OSCC is a major malignancy be strain lineage-specific. He also obtained bout to study how tightly or loosely occurring with high incidence in the black preliminary evidence that host genetic the system is controlled under different and mixed ancestry populations. Marco background modulates the expression conditions. Here, the effects of running Matejcic’s thesis investigates the genetic of innate immune responses to different speed, treadmill running, and fatigue are polymorphisms in xenobiotic metabolizing strains of M. tuberculosis but that this investigated. The nonlinear dynamics of enzymes, with the aim of determining effect is less marked than the strain-related stride timing are quantified, which points to whether functional polymorphic variants effect. the level constraint on the locomotor control alleged to modulate the activation system. He finds increased constraint or detoxification of environmental Supervisor: Professor MP Nicol at higher running speeds, likely arising carcinogens are able to influence (Clinical Laboratory Sciences) from physiological stress. However, this susceptibility to oesophageal squamous Co-supervisor: Professor RJ Wilkinson constraint is also higher for fast treadmill cell carcinoma in these South African (Imperial College, London) running compared to fast overground populations. Part of his thesis is aimed running, likely indicating the influence of at discovering new susceptibility loci for a higher skill requirement in the former. OSCC in South Africans based on results In Medicine: Finally, the fatigue caused by strenuous from a previous genome wide association Mark Emmanuel Engel running intervals exerts a relatively minor study conducted on a Chinese population. Thesis Title: A study of determinants and influence upon system constraint. Analysis A set of black and mixed ancestry South prevalence of rheumatic heart disease in of stride timing demonstrates that control Africans were also genotyped on an Cape Town is normally balanced between stability immunochip platform to investigate the and flexibility, but under certain stressful involvement of immune-related genes in Mark Engel was born in Cape Town conditions, there emerges a regime of oesophageal carcinogenesis. and matriculated from South Peninsula tighter control. High School. He obtained his BSc(Med) Supervisor: Professor I Parker (Hons) in Human Genetics and an MPH in Supervisor: Professor T Noakes (International Centre for Genetic Epidemiology and Biostatistics at UCT. His (Human Biology) Engineering and Biotechnology (ICGEB) education and training were complemented Co-supervisor: Professor S McGregor and Division of Medical Biochemistry) by further postgraduate studies at Leicester (School of Health Promotion and Human University, the University of Ottawa and Performance, Eastern Michigan Harvard University. University) In Medical Microbiology: Mark Engel’s thesis focuses Rajesh Sarkar on rheumatic heart disease (RHD), Thesis Title: The innate immunity to which results from repeated episodes Mycobacterium tuberculosis is dependent of streptococcal throat infection (‘strep on strain lineage and on the host throat’) and acute rheumatic fever (ARF). population He measures, for the first time, the size of the genetic effect of ARF, thereby Rajesh Sarkar has a BSc in Microbiology justifying future large-scale genetic from the University of Pune and a MSc studies. Secondly, his research is the first in Biotechnology from the Bangalore to document the frequency of strep throat University, both in India. He has been in children attending primary health care studying at UCT, in the Division of Medical clinics in Cape Town. He subsequently Microbiology, Department of Clinical derives the first South African clinical Laboratory Science since 2007. prediction rule for ‘strep throat’ in the

24 absence of laboratory confirmation. Johan Jacobus van der Watt In Paediatrics: Lastly, the screening of asymptomatic Thesis Title: HIV-associated sensory Sizulu Moyo schoolchildren provides the first estimate neuropathy in an African cohort; Thesis Title: Optimal tuberculosis case- of burden of RHD using echocardiography a longitudinal study of risk factors finding methodologies for field trials and the extent of carriage of the strep predisposing to antiretroviral induced of new tuberculosis vaccines in young bacterium. Mark Engel’s findings painful neuropathy children emphasise the need for primordial prevention of RHD through addressing Johan van der Watt obtained an MBChB Sizulu Moyo holds an MBChB, an MPH socioeconomic needs of communities, and from the University of Stellenbosch. and a DipClinResAdm. She worked at the importance of primary prevention in He has been studying at UCT, in the the South Africa tuberculosis Vaccine community clinics. Neurology Research Group, Department of Initiative, UCT between 2003 and 2011, Medicine, since 2009. During this time he and currently oversees a number of research Supervisor: Professor B Mayosi has recruited and examined patients from projects at the Health Systems Trust. (Medicine) Crossroads community clinic, performed Sizulu Moyo’s thesis explores genotyping analyses of a candidate locus methodologies for active tuberculosis in the Human Genetics laboratory and (TB) case-finding and case detection to Nasheeta Peer immunology assays on a nested cohort in inform case-finding strategies for clinical Thesis Title: Cardiovascular disease risk the Wilkinson laboratory at the Institute trials of TB vaccines conducted in young factors in the urban black population of of Infectious Disease and Molecular children in high TB burden settings. Her Cape Town Medicine. work demonstrates a high incidence of TB Johan van der Watt’s thesis in children throughout the first five years Nasheeta Peer has an MBChB from the examines the development of neuropathy of life suggesting that clinical trials of new University of Natal and an MBA and MPH in community-based HIV-infected subjects TB vaccines given at birth could increase from UCT. She first registered for her PhD as they commence anti-retroviral therapy. case accrual by extending follow-up for studies in 2009. He finds that painful neuropathy is a at least three years. She also highlights Nasheeta Peer’s thesis is set significant problem with a peak incidence that intensive TB case-finding strategies against a background in which non between 4 and 12 weeks. On the other maximise TB case detection, and that these communicable diseases are becoming a hand, asymptomatic neuropathy steadily strategies detect a mild chest radiographic major cause of morbidity and mortality in increases over the 24 week study period TB phenotype with a clinical hallmark low and middle income countries such as suggesting an alternative mechanism. of growth failure. Her comparison of the South Africa, despite the ongoing burdens Episodes of tuberculosis infections conventional tuberculin skin test (TST) of infectious diseases such tuberculosis and appear as an independent risk factor for and the new QuantiFERON assay shows HIV. Her thesis examines the prevalence neuropathy. He finds half the cohort is that in high TB burden settings where HIV of cardiovascular risk factors in adults vitamin B6 deficient. This is concerning incidence is low the TST is a useful adjunct living in the traditionally black African as isoniazid is an important component of test for detecting TB in young children. townships in Cape Town in 2008/9 and anti-tuberculosis treatment, and he finds Analysis of trial morbidity data shows compares these with the patterns observed slow acetylation status of isoniazid to be that better TB diagnostics are required to in the same communities almost 20 years prevalent, increasing B6 requirements. He differentiate TB from other pulmonary previously. She finds that overweight/ also shows that the early period after starting infections obesity (in women), smoking (in men), anti-retroviral therapy, is associated with diabetes, dyslipidaemia and hypertension increased immune dysregulation which Supervisor: Professor G Hussey are common – their prevalence had risen likely predisposes to neuronal oxidative (Clinical Laboratory Sciences) over time and were the highest reported injury. A cost-effective strategy requires Co-supervisors: A/Professor M Hatherill from subSaharan Africa. Of concern, she attention to micronutritional replacement (School of Child and Adolescent Health); also finds that the management of these prior to starting anti-retroviral therapy. Dr S Verver (Knowledge, Research and conditions is poor with suboptimal rates Policy, KNCV Tuberculosis Foundation, of awareness, treatment and control. Her Supervisor: Professor JM Heckmann The Netherlands thesis is an important contribution to our (Medicine) understanding of the extent of the changing Co-supervisors: Professor R Wilkinson disease pattern in a society undergoing the (Medicine); Professor C Dandara (Human epidemiological transition. Genetics)

Supervisor: Professor N S Levitt (Medicine) Co-supervisor: Professor K Steyn (Medicine)

25 In Pharmacology: In Physiology: Institute, Vrye University and Medical Emmanuel Chigutsa Julian David Pillay Centre, Netherlands) Thesis Title: Population pharmacokinetics Thesis Title: Steps that count! The use of and pharmacokinetic-pharmacodynamic pedometry for physical activity and health modeling of antitubercular drugs promotion in South Africa In Psychiatry: Dickens Howard Akena Emmanuel Chigutsa has a Bachelor of Julian Pillay completed an honours in Thesis title: Screening for depression Pharmacy Honours degree and a Master of Medical science at the University of among HIV-positive patients in a primary Philosophy (Pharmacogenetics), both from Durban-Westville, in Human Anatomy and health care setting in Uganda the University of Zimbabwe. He joined the Pharmacology. He obtained a master’s in UCT Division of Clinical Pharmacology in Public Health at the University of KwaZulu Dickens Akena has an MBChB and an 2009 as a PhD student. Natal. He enrolled for his PhD in 2007 in MMed in Psychiatry from Makerere Emmanuel Chigutsa’s thesis the UCT/MRC Research Unit for Exercise University in Uganda. He has been studying describes the blood concentration-time Science and Sports Medicine, Department at the Department of Psychiatry and Mental profiles for each of the four first line of Human Biology. health at UCT since January 2011 drugs in South African patients with Julian Pillay’s thesis investigates Dickens Akena’s thesis examines tuberculosis (TB). For the most important novel methodological issues related to the a number of aspects about screening for drug, rifampicin, he finds that many use of pedometers as a tool to objectively depression in HIV-positive patients. First, he South African patients have reduced drug measure physical activity volume and documents a high prevalence of depression concentrations due to an African-specific intensity (steps per unit time), and to form among HIV-positive patients. He then genetic makeup which compromises the the basis of a worksite intervention. He explores the availability and accuracy of body’s ability to get enough rifampicin firstly explores the relationship between depression screening instruments validated into the bloodstream (and ultimately the volume and intensity of steps and current in low and middle income countries lungs). He then finds that patients with public health recommendations for by conducting a systematic review. He lower rifampicin concentrations are more physical activity. He demonstrates that the further examines the accuracy of clinician likely to fail treatment than those with association between ambulatory physical administered screening instruments, and high drug concentrations. He develops a activity and important health outcomes demonstrates that these scales are accurate new semi-mechanistic model that enables is strengthened by the inclusion of not and should be routinely administered. quantitative analysis of data comprised only volume of steps, but of intensity. In A locally constructed visual screening of the time it takes for a TB-testing addition, he confirms that self-selected instrument for patients with low literacy machine to record a positive test result pace for ‘brisk’ walking is compatible with was then developed. This is the first of for specimens taken from TB patients. He moderate activity, and supports current its kind in this population and proves also evaluates the adequacy of the current messages that use the term ‘brisk’ walking to be accurate in detecting depression. ofloxacin dose for patients with multidrug as a reference for health-enhancing physical Subsequent assessment is then conducted resistant tuberculosis and finds that it is too activity. Through this series of formative on whether screening for depression could low. His recommendation is that ofloxacin studies, Julian Pillay focuses on intensity- lead to screen positive cases being initiated should be replaced by more potent drugs based steps, such that the outcomes of this into depression care. This shows that such as levofloxacin or moxifloxacin. research can be used to supplement and once patients have screened positive for Using clinical trial simulation, Emmanuel improve physical activity and exercise depression, they are likely to be initiated Chigutsa suggests the optimal study design prescription. The research has additionally into depression care. for clinical studies evaluating the efficacy provided more objective insight into the of antitubercular drugs. ambulatory physical activity patterns of Supervisor: Professor D Stein the South African employed population in (Psychiatry and Mental Health) Supervisor: (Professor H McIlleron) relation to fitness and health. Co-supervisor: Professor J Joska (Medicine, Division of Clinical (Psychiatry and Mental Health) Pharmacology Supervisor: Professor EV Lambert (UCT/ Co-supervisor: Professor C Kirkpatrick MRC Research Unit for Exercise Science (Faculty of Pharmacy and Pharmaceutical and Sports Medicine, Department of Anik Gevers Sciences, Monash University, Melbourne) Human Biology) Thesis Title: An exploration of the nature Co-supervisors: Dr T Kolbe-Alexander of contemporary adolescents’ intimate (UCT/MRC Research Unit for Exercise relationships Science and Sports Medicine, Department of Human Biology); Aník Gevers has a BA(Hons) from Professor D van Mechelen (Department of Grinnell College, Iowa, and an MA in Public and Occupational Health, EMGO clinical psychology from the University & Institute, Vrye University and Medical of Missouri-St Louis, both in the USA. Centre, Netherlands and Honourary While writing her thesis, she worked as a Professor, Faculty of Health Sciences, researcher at the UCT Division of Child University of Cape Town); and Adolescent Psychiatry and the MRC Professor K Proper (Department of Public Gender and Health Unit. and Occupational Health, EMGO & Aník Gevers’ thesis contributes

26 a nuanced understanding of contemporary pharmacological management of their Supervisor: Professor RI Ehrlich adolescents’ intimate relationships to pain. As part of the work, she develops and (Public Health and Family Medicine) inform the development of interventions tests a novel intervention programme using Co-supervisors: Professor G Hussey to prevent intimate partner violence exercise and education to manage pain in in (Vaccines for Africa, Institute of Infectious (IPV), promote sexual and reproductive amaXhosa women living with HIV/AIDS Diseases and Molecular Medicine); health, and promote equitable, enjoyable and having pain. This intervention is found Dr. S.Verver (KNCV Tuberculosis relationships during adolescence. Findings to significantly reduce pain severity and Foundation and CINIMA, Academic from a series of qualitative and quantitative pain interference in this population. This Medical Centre, The Netherlands) studies indicate that adolescent intimate thesis confirms that pain remains a problem relationships are fluid and unstructured, for people living with HIV/AIDS despite highly gendered, and greatly influenced the use of anti-retroviral treatment. Further, In Surgery: by peer relationships. Girls associate the work supports the premise that pain Sarah-Kate Sharp good relationships with having a mutual in PLWHA is biopsychosocial in nature Thesis Title: The in vivo characterisation main partnership with an older, educated and responds to exercise and education of a C-domain specific ACE inhibitor boyfriend in which there was good, open interventions communication, particularly about sexual Sarah-Kate Sharp completed her BSc and her and reproductive health. For boys, a mutual Supervisor: Professor DJ Stein MPhil cum laude in Animal Biotechnology main partnership and very little quarrelling (Psychiatry and Mental Health) at the University of Stellenbosch. She are associated with good relationships. Co-supervisor: Professor J Jelsma joined the Cardiovascular Research Unit Young adolescents report engaging in a (Health and Rehabilitation Sciences) at UCT as a Research Assistant in 2007, variety of sexual behaviours ranging from before choosing to pursue her doctoral kissing to sexual intercourse, with the degree full-time at the same institute in former more common than the latter and In Public Health: 2009. many reported no intercourse experience. Hassan Mahomed Sarah-Kate Sharp’s thesis The thesis highlights specific intervention Thesis title: The incidence of tuberculosis examines the specificity of a novel recommendations based on these findings. in adolescent in the context of proposed C-domain angiotensin-converting enzyme TB vaccine trials. (ACE) inhibitor in blood and the drug’s Supervisor: A/Professor C Mathews phamacokinetics and pharmacodynamics. (Psychiatry and Mental Health) Hassan Mahomed obtained an MBChB ACE inhibitors are extensively used in Co-supervisor: Professor R Jewkes and MMed in Public Health from UCT. the treatment of hypertension and heart (Gender and Health Research Unit, MRC) He was employed by the South African failure but as with most drugs there are Tuberculosis Vaccine Initiative (SATVI) associated side effects. The C-domain from 2004 to 2012, working on several specific inhibitor developed at UCT Romy Elizabeth Parker research projects including work related to has the potential for an improved side Thesis Title: Pain in HIV/AIDS: his PhD. effect profile. Sarah-Kate Sharp shows characteristics, contributing factors and Hassan Mahomed’s thesis that the drug retains its specificity in a the effects of a six-week peer-led exercise examines the occurrence of tuberculosis physiological scenario and has acceptable and education intervention amongst adolescents aged 12-18 years pharmocokinetics. The pharmacodynamic recruited from high schools in a rural assessment shows a satisfactory inhibition Romy Parker has a BSc(Physio) and town outside Cape Town. This is an age of ACE and also allows for a deeper BSc(Med)(Hons) in Exercise Science group in which research on tuberculosis understanding of the interaction of the (Physiology) from UCT. She obtained is lacking. He demonstrates that half of enzyme with its target pathway. Her thesis her MSc(Pain) from Queen Margaret these adolescents are latently infected is an important step towards translation of University in Edinburgh. She is a senior with tuberculosis and one in two hundred this potentially significant new compound lecturer in the Department of Health and develops active tuberculosis disease per for the treatment of cardiovascular disease. Rehabilitation Sciences and has been year. He also identifies demographic, working on her PhD with the Department socio-economic and tuberculosis exposure Supervisor: Dr N. Davies (Surgery) of Psychiatry and Mental Health since factors associated with the occurrence Co-supervisors: Professor E Sturrock 2007. While completing her PhD she has of latent tuberculosis infection as well as (Medical Biochemistry); A/Professor T successfully supervised ten master’s theses active disease. He finds that adolescents Franz (Surgery) focusing on pain. are willing to participate in tuberculosis Romy Parker’s thesis examines vaccine trials depending on the procedures the prevalence and characteristics of involved. His results provide new pain in people living with HIV/AIDS. information in the area of tuberculosis A systematic review and a quantitative research particularly on new tests for clinical study establish that pain is a tuberculosis infection called interferon significant problem in people living with gamma release assays. The results overall HIV/AIDS. She further determines that will be useful both for planning clinical pain in this population is undertreated trials of new tuberculosis vaccines in with only 1% of people living with HIV/ adolescents and for public health action to AIDS with pain receiving adequate control tuberculosis in this age group.

27 11. FACULTY OF SCIENCE In Applied Mathematics: Building on earlier developments, Mohamed Elshazli Sirelakhatim Alnadhief Alfedeel’s work shows how Dean: Professor A Le Roex Abdelwahab the Lemaitre model of spacetime can be Thesis Title: Topics in modified gravity used in creating a procedure to deduce the geometric information about spacetime DEGREE OF DOCTOR Mohamed Abdelwahab has a diploma from galaxy catalogues, especially future OF PHILOSOPHY from the African Institute of Mathematical catalogues that will be more complete. Science and an MSc in Applied The required observations are galaxy In Archaeology: Mathematics from UCT. Since 2007 he brightness, numbers of galaxies, and *Yonatan Sahle Chemere has been studying in the Astrophysics, redshift (that is, how fast galaxies are Thesis Title: Hominin technological Cosmology and Gravity Centre, which is moving away from us). A procedure, based behavior during the later middle located in the departments of Astronomy on the properties of the apparent horizon, Pleistocene in the gademotta formation, and Mathematics and Applied Mathematics. for detecting and correcting systematic main Ethiopian rift During this time he contributed to a major errors in the data is also improved upon. project on Dark Energy and the nature of The method is implemented as a computer Yonatan Sahle has a BEd in History the Gravitational Action. program and tested, providing a proof of from Alemaya University and an MA in Mohamed Abdelwahab’s thesis principle. Archaeology from Addis Ababa University, deals in detail with the cosmological both in Ethiopia. He has been studying at dynamics of an important class of modified Supervisor: A/Professor C Hellaby UCT, in the Archaeology Department, since theories of gravity. These theories provide (Mathematics & Applied Mathematics) 2009. He conducted fieldwork operations in a natural explanation for the late time Ethiopia and published several manuscripts acceleration of the universe, supported on previous ethnoarchaeological work by measurements of the luminosity of Carel Petrus Olivier while writing his thesis. type Ia Supernovae, without the need of Thesis Title: The direct scattering study of Yonatan Sahle’s thesis a Cosmological Constant or dynamical the parametrically driven nonlinear examines the origins of behaviours that Dark Energy. A key result in this thesis Schrödinger equation are characteristic of our species in the is the discovery of cosmic histories able Middle Pleistocene (279,000 years ago). to describe the complete evolution of the Carel Olivier completed his undergraduate He initiated several field explorations of universe from Inflation in the very early studies in Financial Mathematics at the the archaeological site of Gademotta in the Universe, to the present day acceleration, University of Pretoria. After working for Main Ethiopian Rift Valley. In addition to allowing also for an intermediate matter two years in the financial sector in the UK, analytical work on the stone artefacts, he dominated phase needed for large scale he returned to obtain his MSc degree in conducted a tephrostratigraphic analysis structure to form. The techniques developed Applied Mathematics at the University of of surrounding volcanic horizons. This in his thesis have provided the foundations Stellenbosch. He joined the Department of increases our knowledge of the age of for recent studies aimed at constraining Mathematics and Applied Mathematics at this important locality. He compares his modified gravity using data from the Sloan UCT to pursue his PhD degree in 2009. new data to several important eastern Digital Sky Survey. Carel Olivier’s thesis explores a African localities and provides a detailed novel approach to the analysis of solitons in understanding of the evolution of certain Supervisor: Professor P Dunsby nonintegrable systems. The direct scattering technological features. His thesis also (Mathematics and Applied Mathematics) theory is applied to oscillating solitons that identifies features of the fracture of pointed arise as attractors in the parametrically tools which provide the first direct evidence driven nonlinear Schrödinger equation. for projectile weaponry in the early Middle *Alnadhief Hamed Ahmed Alfedeel The relationship between the discrete Pleistocene. The results of this thesis have Thesis Title: The impact of inhomogeneity eigenvalues of the Zakharov-Shabat major implications for how archaeologists on the analysis of cosmological data scattering problem and the soliton’s infer the placement and timing of parameters in this nonintegrable system is populations that employed behaviours that Alnadhief Alfedeel has a BSc from revealed. Four different types of oscillating are unique to our species. Khartoum University, and a postgraduate soliton attractors are identified. Their diploma and MSc from UCT. He has been soliton content is used to gain insight into Supervisor: Dr. DR Braun (Archaeology) pursuing his PhD in Applied Mathematics the period-doubling route to temporal Co-supervisor: Professor JC Sealy at UCT since 2009, specialising in chaos and transition to the trivial attractor. (Archaeology) Cosmology. The role that solitons and radiation play in Alnadhief Alfedeel’s thesis the formation of spatio-temporal chaos is examines how to extract the geometry of also elucidated. spacetime from cosmological observations. The cosmos is so huge, and light takes so Supervisor: Dr NV Alexeeva long to get here, that our observations not (Mathematics and Applied Mathematics) only look out very far, but also very far back in time. Combining this with the curvature of spacetime embodied in Einstein’s theory creates a genuinely challenging exercise.

28 *Obinna Cosmas Umeh In Astronomy: In Botany: Thesis Title: The influence of structure Andry Fitiavana Rajoelimanana Mogamat Igshaan Samuels formation on the evolution of the universe Thesis title: Long-term properties of X-ray Thesis Title: Pastoral mobility in a binaries in the magellanic clouds variable and spatially constrained South Obinna Umeh was born and educated in African environment Nigeria, receiving his undergraduate degree Andry Rajoelimanana received a in Physics from the Federal University of BSc(Hons) in Astronomy from UCT, as Igshaan Samuels was born in Heideveld Technology. He then studied for an MSc part of the NASSP program. He has been and grew up in Mitchells Plain on the Cape in Astrophysics before moving to UCT to studying for his PhD in the Department Flats. He completed BSc, BSc(Hons) and obtain an MSc in String Theory as part of Astronomy since 2007. This has MSc degrees in Ecology at the University of the National Astrophysics and Space involved him in several observing runs of the Western Cape. Science Programme. He then undertook his with the SAAO’s telescopes at Sutherland Igshaan Samuels’s thesis PhD in Cosmology, funded by a prestigious (including SALT), some in conjunction investigates how a mobile pastoral system award from the Square Kilometre Array. with space-based observations. has changed over the last 350 years and Obinna Umeh’s thesis concerns Andry Rajoelimanana’s thesis how livestock herd mobility has adapted mathematically modelling the complex examines the long-term (decades), quasi- to a spatially constrained environment. His array of structure in the universe using periodic variations in X-ray emission research has shown that herd mobility is the Einstein’s General Theory of Relativity. from the most luminous X-ray sources in best livestock management tool to use in Einstein’s theory of gravity is thought the Magellanic Clouds. The majority of order to optimally utilize variable rangeland to govern the dynamics of the Universe these sources are neutron stars accreting resources. His work in the semi-arid region on the largest scales. Our large-scale matter from massive, early-type stars, of Namaqualand in South Africa serves as a cosmological models are coarse-grained designated “BeX” systems. These all have pilot study for how mobile pastoral systems representations of what exists, which have transient X-ray outbursts when the neutron around the world are likely to adapt to much less structure than there really is. star comes close to its companion within future changes. He shows that pastoral An important problem for cosmology is its highly eccentric orbit (typically tens of mobility has been affected significantly determining the influence the small-scale days). But in addition, virtually all BeX by historical legislation but that it has structure in the Universe has on its large- display “super-orbital” modulations with also managed to adapt to socio-economic scale dynamics and observations. Obinna periods of hundreds of days, which have and spatial constraints. Understanding Umeh has quantified this in a variety of been very difficult to study. Exploiting the how these spatially constrained systems ways, and has shown where there remain long-term monitoring archives generated have changed and are currently managed significant problems. In the later part of through the MACHO and OGLE projects could allow millions of people around the his thesis he has focused on gravitational at telescopes in Australia and Chile, Andry world to continue their pastoral livelihoods lensing and has completed for the first time Rajoelimanana uncovers a host of new without compromising the integrity of a monumental calculation which will allow periodicities in these objects, showing semi-arid ecosystems. accurate predictions of the brightening a relationship to the orbital period. of distant objects by the intervening dark Furthermore, he develops a model of how Supervisor: Professor H Hoffman matter distribution of structure in the BeX evolve with time to account, for the (Botany) Universe. Such predictions will play an first time, for their remarkable long-term Co-supervisor: Dr N Allsopp (Botany) important role in accurately determining properties. He also applies similar analysis the nature of Dark Energy from the next techniques to the “supersoft” X-ray sources generation of cosmological surveys such as in the Clouds that are likely progenitors of In Chemistry: the Square Kilometre Array. supernova explosions. Prinessa Chellan Thesis Title: The synthesis and study Supervisor: Professor C Clarkson Supervisor: Professor PA Charles (SAAO/ of multimetallic platinum group metal (Mathematics and Applied Mathematics) UCT: Astronomy, now at University of complexes as in vitro pharmacological Southampton, United Kingdom) agents Co-supervisor: Professor B Warner (Astronomy) Prinessa Chellan received her BSc(Hons) and MSc in Chemistry from UCT. She completed both her master’s and doctoral work within the Organometallic Research Group, and received a UCT Research Associateship in 2012 in recognition of her contribution to research. Prinessa Chellan’s thesis examines the preparation of new multinuclear platinum group metal complexes and their antiparasitic and antitumor activity in vitro. She wished to examine the effect of incorporation of one or more metal centre on cytotoxic

29 activity. A series of cycloplatinated transformations that a molecule might In Computer Science: thiosemicarbazone complexes proved to undergo before interacting with the cancer Olutayo Kehinde Boyinbode be only moderately cytotoxic; as antitumor cell. His research demonstrates that the Thesis Title: Towards an interactive agents, complexation led to a decrease anticancer activity of these complexes is mobile lecturing model: a higher-level in activity. In contrast, she observed that a function of the structure and electronic engagement for enhancing learning functionalisation of two ligand systems, influence of the ligand system. These containing either 4-pyridyl ether or findings lay the foundation for the design Olutayo Boyinbode is a lecturer at the 4-pyridyl ester groups, with ruthenium, of new anticancer drugs. Federal University of Technology, Akure. rhodium and iridium to give di- and She has a BTech in Computer Science trinuclear complexes led to an enhancement Supervisor: A/Professor AT Hutton and from the Federal University of Technology, in antiparasitic activity. Further to this, the Professor JR Moss (deceased) (Chemistry) Akure and an MSc in Computer Science trinuclear analogues were more active than Co-supervisor: Dr GS Smith (Chemistry) from the University of Lagos, both in their dinuclear counterparts. The trinuclear Nigeria. She has been studying at UCT, complexes prepared from the 4-pyridyl in the Computer Science Department and ether ligands demonstrated antiplasmodial Gadzikano Munyuki the ICT4D Research group, since 2009. activities in the nanomolar range suggesting Thesis Title: Molecular mechanism She was one of the ten women who won that complexes of this type have potential of action of tyrocidine antimicrobial the prestigious 2011 LOREAL-UNESCO for further development as antimalarial peptides using NMR spectroscopy and Fellowship award for Women in Science in agents. She also synthesized four computational techniques Sub-Saharan Africa. mono- and multinuclear cyclopalladated Olutayo Boyinbode’s thesis thiosemicarbazone complexes. These Gadzikano Munyuki graduated with a addresses the problem of lack of complexes were investigated as catalyst BSc(Hons) in Applied Chemistry from interaction in face-to-face lectures for a precursors for the Suzuki-Miyaura cross- the National University of Science and new generation of students who ‘live’ with coupling reaction. One of the dinuclear Technology (Zimbabwe) in 2006. He mobile phones and ‘ear plugs’. Although complexes was found to be a robust briefly worked as a high school chemistry traditional lecturing approaches have catalyst; able to efficiently catalyze the teacher before taking up a job as a chemist proven to be effective ways of teaching in coupling of various aryl halides and aryl at Ziscosteel (Redcliff) in June 2007. higher education institutions, most of the boronic acids. Gadzikano moved to University of Cape 21st century students find lectures boring Town to pursue postgraduate studies in and a one-way channel from lecturer to Supervisor: Dr G S Smith (Chemistry) January 2008. students. The lack of engagement in face- Co-supervisor: Professor K Chibale Gadzikano Munyuki’s thesis to-face lectures is particularly problematic (Chemistry) examines the mechanism of action of for students whose mother tongue is not tyrocidine antimicrobial peptides produced English and who struggle to understand by Bacillus aneurinolyticus. The study was both the content of lectures and the *Hadley Steven Clayton carried out using different computational accent of lecturers. Olutayo Boyinbode Thesis Title: Synthesis, structural studies, techniques and experimental methods. The develops a mobile application that anticancer activity and computational results of the study show that there is more plays recorded lectures (from Opencast studies of osmium arene complexes. than one possible mechanisms through Matterhorn) and You Tube videos, and which tyrocidine peptides can destroy allows students to engage with the videos Hadley Clayton was born in Cape Town in bacterial cells. Tyrocidine peptides can in SMS lingo. The tool was evaluated at 1972 and obtained his BSc, BSc(Hons) and self-assemble and bind to the cell membrane UCT and Bindura University of Science MSc degrees in Chemistry at UCT. After surface before disintegrating its structure Education in Zimbabwe. She went on a brief career in the chemical industry leading to the death of the cell. The other to use the evaluation data to develop a he joined the staff of the Department of mechanism involves the formation of high- mobile lecturing framework to understand Chemistry at UNISA in 2000. ordered structures of tyrocidine peptides in students’ engagement with recorded Hadley Clayton’s doctoral the membrane region of the cell leading to lectures whereby removing the limitation research is motivated by the growing the formation of channels. The impartial of traditional lectures using mobile devices. interest in the development of new movememnt of cell particles into and transition metal-based anticancer drugs. out of the membrane through the formed Supervisor: Dr A Bagula His thesis investigates the relationship channels can eventually lead to cell death. (Computer Science) between the structures of complexes of This multipronged approach makes it very Co-supervisor: A/Professor D Ng’ambi osmium and their anticancer activity using difficult for bacteria to develop resistance. (Centre for Educational Technology) X-ray crystallography and computational The outcome of this research is important methods. The study reports on the structural as it can help in the development of new characterisation and anticancer screening and specific antibiotics. of a series of osmium complexes in an attempt to establish a relationship between Supervisor: Professor GE Jackson the 3-D structure of the molecule and its (Chemistry) biological activity. Computationally, he Co-supervisor: Dr G Venter (Chemistry) applies Density Functional Theory (DFT) calculations to investigate the possible

30 *Christopher Chepken Silvian Wanjiku Gitau Six Museum in Cape Town and an effort Thesis Title: Telecommuting in the Thesis Title: Designing Ummeli: a case to effort to preserve personal accounts developing world: a case of the day- for mediated design, a participatory of those who experienced apartheid- labour market approach to designing interactive systems era forced removals. She studies the for semi-literate users storytelling of two District Six ex- Christopher Chepken was born in Keiyo, residents, Joe Schaffers and Noor Ebrahim, in rural Kenya. He holds a BSc(Hons) Silvian Gitau has a BSc(Hons) from Africa ethnographically. Discourse analyses in Computer Science and an MSc in Nazarene University, Nairobi, and an MSc show their narratives are structured as a Applied Computer Science, both from the in Computer Science from UCT. She began series of clauses; incorporate storyteller- University of Nairobi. her PhD research in 2010. She currently audience interactions between clauses Christopher Chepken’s research works as a Senior User Experience where audiences asked the questions and was conceived from an Information and Researcher at Google, where her work the guides asked questions leading to Communication Technologies (ICT) for covers the research and design of Google exchange structure; and incorporate the Development (ICT4D) perspective with products in Emerging Markets. museum objects. These observations are the aim of finding out how and which ICT Silvian Gitau’s thesis explores embodied in the design and implementation interventions could be used to alleviate the role of the mobile technology, of a digital storytelling prototype in the the challenges faced by the job-seekers, specifically the Internet, in social economic form of a virtual environment containing the employers and the organisations development of semi-literate, under served two storyteller agents based on Joe making up the day-labour market. The users in South Africa. Working closely Schaffers and Noor Ebrahim. Quantitative day-labour market addressed is that of with a community of semi-literate users experiments show that simulated questions the casual labourers one sees waiting in Khayelitsha Cape Town, she developed and exchange structures increase user’s on the side of road, in Kenya, Namibia Ummeli. Ummeli is a suite of tools that interest and engagement in the narratives. and South Africa. A key challenge was allows users to build their curricula vitae; Exchange structures additionally increase excessive travel. As a result, the solutions browse and apply for employment and enjoyment of the narratives. Finally, Ilda presented were modelled around using ICT training opportunities; recommend and Ladeira deployed the prototype as an to reduce travel and so the problem could post jobs; receive employment tips and exhibit at the District Six Museum, where be classified as a form of telecommuting. connect to other job seekers, through their it proved highly popular with visitors. The research involved field work study feature phone. Ummeli was built by a from Nairobi, Cape Town and Windhoek, combination of insights drawn from lived- Supervisor: Professor G Marsden and was done in partnership with NGOs in experience, User Centered Design and (Computer Science) and the organizations that run the casual Participatory Design working at Learn to Co-supervisor: Dr L Green labour markets. The experiments involved Earn, an NGO based in Khayelitsha. It was (Social Anthropology) developing and evaluating mobile phone made into a product in October 2011 and and web-based software systems that launched in partnership with Vodacom and allowed for remote task execution in a the Praekelt Foundation. As of May 2013, In Environmental & Geographical resource limited environment such as in the it has nearly 200 000 users. Silvian Gitau’s Science: day-labour market and helped to alleviate research in this area has received a number Christopher David Jack some of their problems. The outcome of of awards. Thesis Title: A Lagrangian moisture Christopher Chepken’s study includes source attribution model and analysis of gaining knowledge about the day-labour Supervisor: Professor G Marsden southern Africa market, ICT-travel relationship and the (Computer Science) software systems adopted by the day- Co-supervisor: Dr J Donner Christopher Jack obtained a BSc in labour market organisations. (Microsoft Research) Computer Science followed by a BSc(Hons) degree in Atmospheric Science from UCT, Supervisor: Professor E Blake after which he joined the university’s (Computer Science) *Ilda Maria Ladeira Climate System Analysis Group (CSAG) Co-supervisor: Professor G Marsden Thesis Title: Simulating storyteller- as a research association. Subsequently, he (Computer Science) audience interactions in digital was appointed to the position of Scientific storytelling: questions, exchange Officer overseeing high performance structures & story objects computing. In 2009 he took leadership of the strategic development of the new Ilda Ladeira has been studying at UCT since UN-funded climate information portal in 1999, completing her BSc(Hons) and MSc CSAG. in Computer Science. Her postgraduate Christopher Jack’s thesis research has focused on understanding examines the question of the moisture and enhancing digital storytelling and the sources for the rainfall over southern Africa. preservation of South African narratives This critical question underpins issues of ranging from indigenous San folklore to climate variability and climate change, and personal Apartheid-era stories. adds to our understanding of the regional Ilda Ladeira’s thesis covers a climate dynamics. His thesis has two seven-year collaboration with the District major foci: the first is the development of

31 an innovative moisture transport model same season over central and northern Supervisor: Professor ME Meadows to track moisture trajectories in the Mozambique and Tanzania. This study (Environmental and Geographical atmosphere and evaluate the accumulation highlights the importance of including Science) and loss of moisture. The second is the all biomass burning emissions, from the Co-supervisor: Dr BM Chas application of the model to atmospheric aerosols directly released from fires to the (University of Montpellier II, France) data to understand the sources of moisture precursor gases, as different circulation for rainfall over the subcontinent, and the patterns are likely to be induced over all relation of these to the changing circulation seasons, regardless of how large the aerosol In Molecular & Cell Biology: patterns. His thesis gives new insight of emissions and/or concentrations are. Joni Frederick the processes, showing that the regional Thesis Title: Genetic characterization of land surface plays a larger role than Supervisor: Dr M Tadross Rhodococcus rhodochrous ATCC BAA- previously thought as a moisture source for (Environmental and Geographical 870 with emphasis on nitrile hydrolysing regional precipitation, and revealing how Science) enzymes the influence of the regional ocean changes Co-supervisor: Professor B Hewitson under different synoptic conditions. In (Environmental and Geographical Joni Frederick has a BSc(Hons) and an MSc addition, a previously unidentified high Science) from the University of the Witwatersrand level westerly moisture source is located, in Johannesburg. She conducted her PhD a source region that previous studies have research in the Electron Microscope Unit associated with dry conditions over the Lynne Julia Quick and the Department of Molecular and Cell interior. His work advances our knowledge Thesis Title: Late Quaternary Biology at UCT, in collaboration with the of regional atmospheric dynamics with palaeoenvironments of the southern Cape, Enzyme Technologies Group in the CSIR particular value to the understanding of South Africa: palynological evidence from Biosciences Unit. During this time she climate variability. three coastal wetlands contributed to a number of biocatalysis research projects. Supervisor: Professor B Hewitson Lynne Quick obtained her BSc, Joni Frederick’s thesis explores (Environmental and Geographical BSc(Hons) and MSc (with distinction) in the nitrile converting enzymes from a Science) Environmental & Geographical Science biotechnologically useful organism which from UCT, and went to on to develop her was isolated from soil in Johannesburg research into the past environments of with a view to using this activity in Genito Amos Maure parts of the Western Cape for her doctoral environmentally friendly biocatalytic Thesis Title: Effects of biomass-burning research. processes. The entire genome of the aerosol loading on southern African Lynne Quick’s thesis addresses organism is sequenced, assembled, climate the issue of how environments change annotated and mined for industrially useful over time and has interpreted important gene targets. Her study of Rhodococcus Genito Maure has a BSc(Hons) in Physics sedimentary records that span up to the last rhodochrous ATCC BAA-870 presents the from the Eduardo Mondlane University in 120,000 years in three coastal wetland sites first full sequence of an organism in this Mozambique and an MSc in Physics from in the region. The key form of evidence used class. In addition to offering more insight the University of Venda. He has been in the thesis is fossil pollen from flowering into Rhodococcus phylogeny, the sequence studying at UCT, in the Climate System plants preserved in organic deposits reveals a number of biotechnologically Analysis Group, since 2007. He was the that have accumulated intermittently in important protein targets. The nitrilase first Mozambican student to join the group. inter-dunal depressions. One of sites, at and nitrile hydratase enzymes are isolated, Apart from his PhD studies, he also lectures Vankervelsvlei near Knysna, provides and expression systems constructed for at the Department of Physics at his home the longest record yet recovered from the independent expression and purification for university in Maputo. region for vegetation change and provides a their further characterization studies. The Genito Maure’s thesis assesses glimpse into the environmental conditions nitrilase and nitrile hydratase expression the impact of biomass-burning aerosol that prevailed there during the last inter- systems facilitate their structural and loading on southern African climate glacial. Assessed in conjunction with plant mechanistic study, offering several future using complex climate models. He finds biomarker, sedimentological, geochemical possible enzyme modification strategies. that not only negative changes of surface and charcoal data, these pollen sequences temperature can be induced, as previous indicate distinct changes in late Pleistocene Supervisor: Professor BT Sewell studies have suggested, but positive changes and Holocene palaeoenvironments. (Molecular and Cell Biology) can also be induced by the inclusion of Correlations of these records with changes Co-supervisor: Professor D Brady sulphate aerosols nucleated from biomass in Antarctic sea ice presence and its (University of the Witwatersrand) burning sulphur dioxide, which implied influence on the latitudinal position and/ increased lower–level convergence over or intensity of the westerly wave belt is these regions, and, consequently, increased suggested as a feasible mechanism for the precipitation. The most significant impacts observed environmental changes during are an increase in daily precipitation, for these periods and significantly improves December–to–February, over the Atlantic our understanding of the dynamics of the Ocean (near the coast of Angola) and a climate and vegetation relationships in the prominent reduction found during the region.

32 In Physical Oceanography: scale. By using a careful analysis of consistent with the calculations performed Issufo Ferrao Mario Halo the temperature dependence of the within the framework of the Random Thesis Title: The Mozambique channel characteristic current-voltage behaviour Phase Approximation nuclear model. This eddies: characteristics and mechanisms of of the nanoparticle networks, he was able agreement of the new data with the model formation to establish the presence of thermally is also shown as able to reproduce the data activated charge transport with four from other vibrational structures in the rare Issufo Halo came to Cape Town from the different activation energies for electrical earth region, and is compelling evidence Eduardo Mondlane University in Maputo conduction in the novel material. Using against the idea that these nuclei can be in 2006. An opportunity to complete an extensive variable temperature and deformed into a tetrahedral shape. MSc in Oceanography at UCT enabled him variable field Hall effect measurements to stay in South Africa, where seven years and a rigorous analysis of the temperature Supervisor: Professor DG Aschman later he has now qualified with a PhD in dependence of the statistics of charge (Physics) ocean modelling. carriers and mobility data, the microscopic Co-supervisor: Dr RA Bark Issufo Halo’s thesis uses the features of the charge transport were (iThemba LABS) SWIM ocean model to investigate the resolved. Batsirai Magunje’s thesis not mesoscale circulation of the Mozambique only presents the first direct evidence of Channel. The evaluation of the results a hopping percolation mode of charge Yingwen Zhang has shown a good agreement between conduction, but also identifies the individual Thesis Title: Applications of QCD sum the model and observations. The model activation energies for transport according rules at finite temperature outputs have shown that both cyclonic and to their physical origin The understanding anticyclonic eddies are generated within of these unique transport features makes Yingwen Zhang has a BSc in Physics and a the Mozambique Channel. These eddies this novel material a strong candidate for BSc(Hons) and MSc in Theoretical Physics have been tracked using an eddy detection a variety of electronic devices which are from UCT. He was awarded a UCT algorithm. The algorithm has shown that already finding industrial and commercial Research Associateship in 2010. cyclonic eddies are more dominant than application. Beyond their application Yingwen Zhang’s research their anticyclonic counterparts and that to silicon, the models which Batsirai involves the study of Quantum they are generated in the north and then Magunje developed are also applicable to Chromodynamics at finite temperature and propagate southwestwards. The annual the description of the electronic behaviour density using the method of QCD Sum frequency of these eddies are consistent of a wide range of other conducting and Rules. Using this method, he was able to with the in-situ observations derived from semiconducting particle networks. analytically determine whether mesons, the Dutch LOCO mooring array at the a particle composed of a quark and an narrows of the channel. They are deep Supervisor: Professor DT Britton anti-quark, will still be present at high reaching and interact with the Mozambican (Physics) temperature and density. The result of his continental shelf. The eddy census have Co-supervisor: Professor M Härting studies show signs of presence of heavy suggested that cyclonic eddies dominate (Physics) quark mesons at very high temperatures over the anticyclones in the Mozambique whereas light quark mesons will disappear. Channel. An extension of the method to finite Maciej Andrzej Stankiewicz density for light quark mesons also show Supervisor: Dr Isabelle Ansorge Thesis Title: Physics of low and signs of disappearance at large densities. (Oceanography) intermediate spin states of atomic nuclei in This study is crucial in understanding the Co-supervisors: Dr P Penven the mass A ~ 160 region) conditions of the universe shortly after (Oceanography); Dr S Bernard the Big Bang, when the universe was still (Oceanography) Maciej Stankiewicz was born in Poland, very hot and dense. The results of his PhD and moved to South Africa in 1990. He thesis are important in connection with has been studying at UCT since 2000, current experiments at the Brookhaven In Physics: obtaining a BSc, BSc (Hons) and an MSc National Laboratory (USA), and at Batsirai Magunje in Physics. CERN (Switzerland), which recreate the Thesis Title: Charge transport in printed Maciej Stankiewicz’s thesis temperatures prevalent in the Universe at silicon nanoparticle networks involves the study of a very particular form such an early stage. of nuclear excitation. A set of experiments Batsirai Magunje holds a BSc(Hons) and have been performed at iThemba LABS Supervisor: Professor C A Dominguez an MSc from the University of Zimbabwe. to create several rare earth nuclei in their (Physics) He has been studying as a full-time student excited form, and by use of the AFRODITE Co-supervisor: Professor A Peshier at UCT since 2007 in the NanoSciences gamma-ray spectrometer, information (Physics) Innovation Centre in the Department of about the nuclear structure has been Physics. inferred from the collected gamma-rays. Batsirai Magunje’s thesis He identifies new structures in the nuclides provides a breakthrough in understanding 158Dy and 160Er, and finds a discrepancy the charge transport in printed silicon between the de-excitation modes of even- nanoparticle networks both at the and odd-spin vibrational structures. These macroscopic scale and at the microscopic experimental results are shown to be

33 In Zoology: Jessica Mary Shaw Megan Clair Laird Thesis Title: Power line collisions in the Thesis Title: Taxonomy, systematics and Karoo: conserving Ludwig’s Bustard biogeography of South African actiniaria and corallimorpharia Jessica Shaw has a BSc in Ecology with Honours in Wildlife Management from Megan Laird has a BSc from UCT, where the University of Edinburgh. She came she majored in Zoology and Ecology. to South Africa in 2008 to study for an In 2007 she obtained her BSc(Hons) in MSc in Conservation Biology at UCT. Zoology and then went on to study the During this degree, she became interested biodiversity and distribution patterns of in the conflicts between birds and power sea anemones around the South African infrastructure, and has worked with Eskom coastline, focusing specifically on the and conservation NGOs on the issue since discovery of new and previously unreported then. species. Jessica Shaw’s thesis investigates Megan Laird’s thesis reviews the the impacts of power line collisions on the systematics of Actiniaria, a group which regionally endemic Ludwig’s Bustard and has received little attention over the past other large birds of the Karoo. Combining 74 years. Her work includes descriptions road and aerial counts, power line surveys, of two species new to science and an satellite tracking and stable isotope analyses illustrated guide to all known species in the she confirms the high susceptibility of these region, allowing non-specialists to easily birds to such unnatural mortality. More identify sea anemones by means of a step than 40% of the South African population by step key. In addition, her thesis includes may die annually on power lines, which a biogeographic chapter which collates surprisingly Ludwig’s Bustard seems able decades of data collected from previously to currently sustain. Tracking this nomadic unidentified museum specimens, diver species reveals some familiarity with the photographic records and trawl data landscape which may reduce the probability providing insight into the endemicity, of collision, and previously unsuspected distribution and depth ranges of each fidelity to eastern sites in summer where species. During the course of the study, most juveniles apparently originate. She twelve new species records were recorded also establishes a large-scale experiment to for the region, 40 range extensions were test line marking devices, and recommends reported and three new species were that this mitigation measure should be discovered. implemented on all new power lines to stem the heavy toll taken by the expanding Supervisor: Professor C Griffiths power grid. (Zoology) Supervisor: A/ Professor P Ryan (Percy FitzPatrick Institute, Biological Sciences) Co-supervisor: Dr A Jenkins (Percy FitzPatrick Institute, Biological Sciences)

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