2020 CA-1 TUTORIAL TEXTBOOK 14Th Edition
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Spring 2009 Student Journal
Volume 8 Number 1 Spring 2009 The International Student Journal of Nurse Anesthesia TOPICS IN THIS ISSUE MS & ECT Cardioprotection of Volatile Agents Hyperthermic Chemotherapy Intubating LMA Pierre Robin Syndrome Alpha Thalassemia Latex Allergy & Spina Bifida Distorted Upper Airway Volunteerism – Honduras INTERNATIONAL STUDENT JOURNAL OF NURSE ANESTHESIA Vol. 8 No. 1 Spring 2009 Editor - in - Chief Ronald L. Van Nest, CRNA, JD Associate Editors Vicki C. Coopmans, CRNA, PhD Julie A. Pearson, CRNA, PhD EDITORIAL BOARD & SECTION EDITORS Pediatrics Janet A. Dewan, CRNA, MS Northeastern University Obstetrics Greg Nezat, CRNA, PhD Navy Nurse Corps Anesthesia Program Research & Capstone Joseph E. Pellegrini, CRNA, University of Maryland PhD Regional / Pain Christopher Oudekerk, CRNA, Uniformed Services Universi- DNP ty of the Health Sciences Cardiovascular Michele Gold, CRNA, PhD University of Southern Cali- fornia Thoracic/ Fluid Balance Lori Ann Winner, CRNA, MSN University of Pennsylvania Unique Patient Syndromes Kathleen R. Wren, CRNA, PhD Florida Hospital College of Health Sciences Equipment Carrie C. Bowman Dalley, Georgetown University CRNA, MS Pharmacology Maria Magro, CRNA, MS, University of Pennsylvania MSN Pathophysiology JoAnn Platko, CRNA, MSN University of Scranton Special Surgical Techniques Russell Lynn, CRNA, MSN University of Pennsylvania 1 Airway & Respiration Michael Rieker, CRNA, DNP Wake Forest University Baptist Medical Center ,Nurse Anesthesia Program, Univer- sity of North Carolina at Greensboro Neurology & Neurosurgery -
Data Driven Investigation of Bispectral Index Algorithm
www.nature.com/scientificreports OPEN Data Driven Investigation of Bispectral Index Algorithm Hyung-Chul Lee, Ho-Geol Ryu, Yoonsang Park , Soo Bin Yoon, Seong Mi Yang, Hye-Won Oh & Chul-Woo Jung Received: 7 January 2019 Bispectral index (BIS), a useful marker of anaesthetic depth, is calculated by a statistical multivariate Accepted: 9 September 2019 model using nonlinear functions of electroencephalography-based subparameters. However, only Published: xx xx xxxx a portion of the proprietary algorithm has been identifed. We investigated the BIS algorithm using clinical big data and machine learning techniques. Retrospective data from 5,427 patients who underwent BIS monitoring during general anaesthesia were used, of which 80% and 20% were used as training datasets and test datasets, respectively. A histogram of data points was plotted to defne fve BIS ranges representing the depth of anaesthesia. Decision tree analysis was performed to determine the electroencephalography subparameters and their thresholds for classifying fve BIS ranges. Random sample consensus regression analyses were performed using the subparameters to derive multiple linear regression models of BIS calculation in fve BIS ranges. The performance of the decision tree and regression models was externally validated with positive predictive value and median absolute error, respectively. A four-level depth decision tree was built with four subparameters such as burst suppression ratio, power of electromyogram, 95% spectral edge frequency, and relative beta ratio. Positive predictive values were 100%, 80%, 80%, 85% and 89% in the order of increasing BIS in the fve BIS ranges. The average of median absolute errors of regression models was 4.1 as BIS value. -
Authors Conducted an E-Mail Survey of Anesthesiologists in the US in 2010
Appendix 2: Reference 1 Methods: Authors conducted an e-mail survey of Anesthesiologists in the US in 2010. Results: “Five thousand anesthesiologists were solicited; 615 (12.3%) responses were received. Twenty-four percent of respondents had installed an AIMS, while 13% were either installing a system now or had selected one, and an additional 13% were actively searching. Larger anesthesiology groups with large case loads, urban settings, and government affiliated or academic institutions were more likely to have adopted AIMS. Initial cost was the most frequently cited AIMS barrier. The most commonly cited benefit was more accurate clinical documentation (79%), while unanticipated need for ongoing information technology support (49%) and difficult integration of AIMS with an existing EMR (61%) were the most commonly cited problems.” [Trentman TL, Mueller JT, Ruskin KJ, Noble BN, Doyle CA. Adoption of anesthesia information management systems by US anesthesiologists. J Clin Monit Comput 2011;25:129–35.] Reference 2 Joint Commission Report. 60 [Kohn L, Corrigan JM, Donaldson MS. To Err is Human: Building a Safer Health System. Report from the Committee on Quality of Health Care in America. Washington DC: The Joint Commission journal on quality improvement, 1999:227–34.] Reference 3 Excerpt: “The Department of Health and Human Services (DHHS) released two proposed regulations affecting HIT (www.healthit.hhs.gov). The first, a notice of proposed rule- making (NPRM), describes how hospitals, physicians, and other health care professionals can qualify for billions of dollars of extra Medicare and Medicaid payments through the meaningful use of electronic health records (EHRs). The second, an interim final regulation, describes the standards and certification criteria that those EHRs must meet for their users to collect the payments. -
Unesco – Eolss Sample Chapters
PHARMACOLOGY – Vol. II - Anesthetics - Amanda Baric and David Pescod. ANESTHETICS Amanda Baric and David Pescod. Department of Anesthesia and Perioperative medicine, The Northern Hospital, Melbourne, Australia. Keywords: Anesthesia, pharmacology, inhalational, neuromuscular blockade, induction agent, local anesthetic. Contents 1. Inhalation agents 1.1. Introduction 1.2. Pharmacokinetics and Pharmacodynamics 1.3. Specific Agents 1.3.1. Diethyl Ether (Ether) 1.3.2. Chloroform 1.3.3. Cyclopropane 1.3.4. Trichloroethylene 1.3.5. Halogenated Alkanes and Ethers 1.3.6. Nitrous Oxide. 1.3.7. Xenon 2. Neuromuscular blocking agents. 2.1. Introduction 2.2. Non-Depolarizing Muscle Relaxants 2.2.1. Tubocurarine (1935) 2.2.2. Metocurine (dimethyl tubocurarine chloride/bromide) 2.2.3. Alcuronium (1961) 2.2.4. Gallamine (1948) 2.2.5. Pancuronium (1968) 2.2.6. Vecuronium (1983) 2.2.7. Atracurium (1980s) 2.2.8. Cis-atracurium (1995) 2.2.9. Mivacurium (1993) 2.2.10. Rocuronium (1994) 2.2.11. SugammadexUNESCO (2003) – EOLSS 2.2.12. Rapacuronium 2.3. Reversal Drugs (Anticholinesterase) 2.4. DepolarizingSAMPLE Muscle Relaxants (Suxamethonium CHAPTERS or Succinylcholine) 3. Local anesthetics 3.1. Introduction 3.2. Pharmacokinetics and Pharmacodynamics 3.3. Toxicity 3.4. Specific Agents 3.4.1. Cocaine 3.4.2. Procaine 3.4.3 Chloroprocaine 3.4.4. Tetracaine (Amethocaine) ©Encyclopedia of Life Support Systems (EOLSS) PHARMACOLOGY – Vol. II - Anesthetics - Amanda Baric and David Pescod. 3.4.5. Lidocaine 3.4.6. Prilocaine 3.4.7. Mepivacaine 3.4.8. Bupivacaine 3.4.9. Ropivacaine 3.4.10. Eutectic Mixture of Local Anesthetics (EMLA) 4. Intravenous Induction Agents 4.1. -
Femoral and Sciatic Nerve Blocks for Total Knee Replacement in an Obese Patient with a Previous History of Failed Endotracheal Intubation −A Case Report−
Anesth Pain Med 2011; 6: 270~274 ■Case Report■ Femoral and sciatic nerve blocks for total knee replacement in an obese patient with a previous history of failed endotracheal intubation −A case report− Department of Anesthesiology and Pain Medicine, School of Medicine, Catholic University of Daegu, Daegu, Korea Jong Hae Kim, Woon Seok Roh, Jin Yong Jung, Seok Young Song, Jung Eun Kim, and Baek Jin Kim Peripheral nerve block has frequently been used as an alternative are situations in which spinal or epidural anesthesia cannot be to epidural analgesia for postoperative pain control in patients conducted, such as coagulation disturbances, sepsis, local undergoing total knee replacement. However, there are few reports infection, immune deficiency, severe spinal deformity, severe demonstrating that the combination of femoral and sciatic nerve blocks (FSNBs) can provide adequate analgesia and muscle decompensated hypovolemia and shock. Moreover, factors relaxation during total knee replacement. We experienced a case associated with technically difficult neuraxial blocks influence of successful FSNBs for a total knee replacement in a 66 year-old the anesthesiologist’s decision to perform the procedure [1]. In female patient who had a previous cancelled surgery due to a failed tracheal intubation followed by a difficult mask ventilation for 50 these cases, peripheral nerve block can provide a good solution minutes, 3 days before these blocks. FSNBs were performed with for operations on a lower extremity. The combination of 50 ml of 1.5% mepivacaine because she had conditions precluding femoral and sciatic nerve blocks (FSNBs) has frequently been neuraxial blocks including a long distance from the skin to the used for postoperative pain control after total knee replacement epidural space related to a high body mass index and nonpalpable lumbar spinous processes. -
Pharmacology – Inhalant Anesthetics
Pharmacology- Inhalant Anesthetics Lyon Lee DVM PhD DACVA Introduction • Maintenance of general anesthesia is primarily carried out using inhalation anesthetics, although intravenous anesthetics may be used for short procedures. • Inhalation anesthetics provide quicker changes of anesthetic depth than injectable anesthetics, and reversal of central nervous depression is more readily achieved, explaining for its popularity in prolonged anesthesia (less risk of overdosing, less accumulation and quicker recovery) (see table 1) Table 1. Comparison of inhalant and injectable anesthetics Inhalant Technique Injectable Technique Expensive Equipment Cheap (needles, syringes) Patent Airway and high O2 Not necessarily Better control of anesthetic depth Once given, suffer the consequences Ease of elimination (ventilation) Only through metabolism & Excretion Pollution No • Commonly administered inhalant anesthetics include volatile liquids such as isoflurane, halothane, sevoflurane and desflurane, and inorganic gas, nitrous oxide (N2O). Except N2O, these volatile anesthetics are chemically ‘halogenated hydrocarbons’ and all are closely related. • Physical characteristics of volatile anesthetics govern their clinical effects and practicality associated with their use. Table 2. Physical characteristics of some volatile anesthetic agents. (MAC is for man) Name partition coefficient. boiling point MAC % blood /gas oil/gas (deg=C) Nitrous oxide 0.47 1.4 -89 105 Cyclopropane 0.55 11.5 -34 9.2 Halothane 2.4 220 50.2 0.75 Methoxyflurane 11.0 950 104.7 0.2 Enflurane 1.9 98 56.5 1.68 Isoflurane 1.4 97 48.5 1.15 Sevoflurane 0.6 53 58.5 2.5 Desflurane 0.42 18.7 25 5.72 Diethyl ether 12 65 34.6 1.92 Chloroform 8 400 61.2 0.77 Trichloroethylene 9 714 86.7 0.23 • The volatile anesthetics are administered as vapors after their evaporization in devices known as vaporizers. -
Dexmedetomidine During Suprazygomatic Maxillary Nerve Block for Pediatric Cleft Palate Repair, Randomized Double-Blind Controlled Study Mohamed F
Korean J Pain 2020;33(1):81-89 https://doi.org/10.3344/kjp.2020.33.1.81 pISSN 2005-9159 eISSN 2093-0569 Original Article Dexmedetomidine during suprazygomatic maxillary nerve block for pediatric cleft palate repair, randomized double-blind controlled study Mohamed F. Mostafa1, Fatma A. Abdel Aal1, Ibrahim Hassan Ali1, Ahmed K. Ibrahim2, and Ragaa Herdan1 1Department of Anesthesia and Intensive Care, Faculty of Medicine, Assiut University, Assiut, Egypt 2Department of Public Health, Faculty of Medicine, Assiut University, Assiut, Egypt Received July 26, 2019 Revised December 3, 2019 Background: For children with cleft palates, surgeries at a young age are necessary Accepted December 3, 2019 to reduce feeding or phonation difficulties and reduce complications, especially respiratory tract infections and frequent sinusitis. We hypothesized that dexmedeto- Correspondence midine might prolong the postoperative analgesic duration when added to bupiva- Mohamed F. Mostafa caine during nerve blocks. Department of Anesthesia and Intensive Methods: Eighty patients of 1-5 years old were arbitrarily assigned to two equal Care, Assiut University Hospital, Faculty groups (forty patients each) to receive bilateral suprazygomatic maxillary nerve of Medicine, Assiut University, Assiut blocks. Group A received bilateral 0.2 mL/kg bupivacaine (0.125%; maximum vol- 71515, Egypt Tel: +20-1001123062 ume 4 mL/side). Group B received bilateral 0.2 mL/kg bupivacaine (0.125%) + 0.5 Fax: +20-88-2333327 μg/kg dexmedetomidine (maximum volume 4 mL/side). E-mail: [email protected] Results: The modified children’s hospital of Eastern Ontario pain scale score was significantly lower in group B children after 8 hours of follow-up postoperatively (P < 0.001). -
Moderate Sedation
MODERATE SEDATION A SELF STUDY GUIDE Part I Self Study Guide Part II ASA Practice Guidelines for Sedation And Analgesia by Non-Anesthesiologists Part III Sedation/Analgesia Policy 1 Introduction Diagnostic and surgical procedures are being performed in a variety of settings throughout the hospital. This self-study program has been developed to increase your awareness and reinforce your understanding of the use of moderate sedation. It includes indications/contraindications for moderate sedation, accepted medications administration guidelines, and monitoring requirements. Part I is dedicated to an overall review of the principles of moderate sedation, Part II includes the American Society of Anesthesiology’s Practice Guidelines For Sedation And Analgesia by Non- Anesthesiologist. Part 3 is a post-test. Completion of this self-study packet includes learning the following material, satisfactory completion of the post-test and returning the post-test to the Medical Staff Office. Completion of this self-study is required to qualify for privileges to administer Moderate Sedation at St. David’s Medical Center. Purpose The purpose of this self-study packet is to increase and reinforce your knowledge of responsibilities and guidelines associated with the care of individuals requiring moderate sedation. On completion of this self-study program, you should be able to: 1. Recognize indications and contraindication for moderate sedation. 2. State appropriate monitoring techniques and requirements for patients undergoing moderate sedation. 3. Identify medications frequently used for moderate sedation, administration guidelines, and potential complications/side-effects. 4. Evaluate and manage expected and unexpected outcomes of moderate sedation Part I Definition Conscious Sedation more accurately termed Sedation/Analgesia or Moderate Sedation describes a state that allows patients to tolerate unpleasant procedures while maintaining adequate cardiorespiratory function and the ability to respond purposefully to verbal commands and tactile stimulation. -
Northwest Arkansas Regional Ems Protocols
Regional Protocol PROTOCOL SECTION NORTHWEST ARKANSAS REGIONAL EMS PROTOCOLS 2019 REVISION 2019 a Regional Protocol PROTOCOL SECTION TABLE OF CONTENTS……………………………………………………………………………….b - e INTRODUCTORY STATEMENT………………......……………………………………………….........f PARTICIPATING AGENCIES………………………………………………………………………….…………..g 2019 DEPARTMENT MEDICAL DIRECTORS & SIGNATURE………………..…………………………........h SECTION ONE - PROTOCOLS GENERAL PROTOCOLS UNIVERSAL PATIENT CARE ................................................................................................................... 1 CHEMICAL EXPOSURE (HAZMAT) ......................................................................................................... 2 CHEMICAL SEDATION FOR VIOLENT PATIENT .................................................................................... 3 PAIN MANAGEMENT ............................................................................................................................... 4 SPINAL RESTRICTION ............................................................................................................................ 5 VASCULAR ACCESS ............................................................................................................................... 6 RESPIRATORY OXYGEN ADMINISTRATION……….…………………………………………………………..…………………..7 GENERAL AIRWAY MANAGEMENT………………….……………………………………..…………………….8 ADVANCED AIRWAY MANAGEMENT….……………………………………………………..…………………..9 PHARMACOLOGICAL ASSISTED INTUBATION (PAI)………………….……………………………………..10 ALLERGIC REACTION—ANAPHYLAXIS….……………………………………………………………………..11 -
The Use of Remifentanil As the Primary Agent for Analgesia in Parturients
The Use Of Remifentanil As The Primary Agent For Analgesia In Parturients Author: Bryan Clifford Anderson, DNAP, CRNA Learning Objectives for this Self Study: The Importance of Exploring Remifentanil as an Upon completion of this study, the CRNA will be able to: Option for Treating Labor Pain The use of remifentanil in the parturient as the primary analgesic is 1. Discuss the significance of remifentanil use as a primary analgesic significant for several reasons; the most salient of which is the basic human agent in parturients for whom neuraxial anesthesia is not an option. right to the management of pain. Pain, as defined by the International Association for the Study of Pain (IASP), is “an unpleasant sensory and 2. Identify clients in which neuraxial anesthesia might be contraindicated. emotional experience associated with actual or potential tissue damage.” 2 Labor is a cause of severe pain for many women and is a problem that should 3. Compare the efficacy of select medications in the control of pain be addressed and managed in accordance with the needs and wishes of the in paturients. individual patient. Interventions that alleviate or eliminate pain are not merely a matter of beneficence, but also form part of the duty to prevent harm.3 4. Appraise findings in current evidence to determine to what extent The variations in pain perception among women in labor creates an essential remifentamil is a viable option for pain management in parturient patients. component in the administration of anesthesia in the provision of patient- centered anesthesia care. One recent study identifies that the perception of 5. -
A Comparison of Wilson Risk Sum Score and Combination of Modified Mallampati Classification, Hyomental Distance Ratio, Ratio Of
Jebmh.com Original Research Article A Comparison of Wilson Risk Sum Score and Combination of Modified Mallampati Classification, Hyomental Distance Ratio, Ratio of Height to Sternomental and Thyromental Distances for Predicting Difficult Laryngoscopy in Indian Population Deepak Kumar1, Saurabh Bhargava2, Ravindra Singh Sisodiya3, Deepak Tiwari4 1Department of Anaesthesia, National Institute of Medical Sciences and Research Centre, Jaipur, Rajasthan, India. 2, 4 Department of Emergency Medicine, National Institute of Medical Sciences and Research Centre, Jaipur, Rajasthan, India. 3Department of Anaesthesia, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India. ABSTRACT BACKGROUND A few patients of apparently normal appearance unexpectedly present with great Corresponding Author: difficulties during intubation which may lead to potentially serious consequences. Dr. Deepak Tiwari, Thus, we worked on this area with the aim to determine the ability to predict 109 Avar Faculty Block, Nims University, Shobha Nagar, difficult visualisation of larynx using the following preoperative airway predictors: Delhi-Jaipur Highway, MMC (Modified Mallampati Classification), RHSMD (Ratio of Height to Sternomental Jaipur - 302013, Distance), RHTMD (Ratio of Height to Thyromental) and HMDR (Hyomental Rajasthan, India. Distance Ratio) and comparison of these with WRSS (Wilson Risk Sum Score), in E-mail: [email protected] isolation and in combination. DOI: 10.18410/jebmh/2020/620 METHODS A double-blind, prospective study was carried out on 300, ASA grade I or II How to Cite This Article: patients posted for elective surgery in supine position under general anaesthesia. Kumar D, Bhargava S, Sisodiya RS, et al. A comparison of Wilson risk sum score Different parameters were recorded in pre-op period and Cormack-Lehane grading and combination of modified Mallampati and difficulty of intubation was recorded at the time of intubation. -
The Bispectral Index Response to Tracheal Intubation Is Similar In
458 GENERAL ANESTHESIA The bispectral index response to tracheal intuba- tion is similar in normotensive and hypertensive patients [La réponse de l’index bispectral à l’intubation endotrachéale est similaire chez les patients normotendus et hypertendus] Masayasu Nakayama MD,* Hiromichi Ichinose MD,† Shuji Yamamoto MD,† Noriaki Kanaya MD,* Akiyoshi Namiki MD PhD* Purpose: To compare the hemodynamic and bispectral index (BIS) Conclusion : Les patients hypertendus ou non réagissent par la même responses to tracheal intubation in normotensive and hypertensive réaction d’éveil (mesurée par le BIS) à l’intubation endotrachéale mal- patients. gré l’augmentation de la réponse vasopressive chez les hypertendus. Method: Three minutes after induction of anesthesia with thiamy- lal and fentanyl, tracheal intubation was performed in 24 nor- motensive and 22 hypertensive patients. Heart rate (HR), mean arterial pressure (MAP), and BIS were measured every minute. HE bispectral index (BIS), obtained from Results: Tracheal intubation increased HR, MAP, and BIS in both bispectral analysis of the electroencephalo- normotensive and hypertensive patients. The increase in MAP was gram (EEG), reflects the hypnotic compo- significantly greater in hypertensive patients than in normotensive nent of anesthesia.1–3 Previous studies have patients, but there were no differences in HR or BIS in the two T shown that tracheal intubation is associated with groups of patients. increases in BIS as well as heart rate (HR) and blood Conclusion: Patients with and without hypertension exhibit the pressure.4–6 Therefore, intubation is likely to affect same arousal response (as measured by BIS) to tracheal intubation both the hypnotic and antinociceptive components of despite the enhanced vasopressor response in hypertensive anesthesia.