ORGANIC UVA/UVB FILTERS AND MICROFINE INORGANIC PIGMENTS FROM SYMRISE Symrise has an extensive portfolio of UV filters comprising UVB and UVA filters with the Neo Heliopoan® trade name along with inorganic pigments to protect against UV damage. Neo Heliopan® ORGANIC FILTERS

The Neo Heliopan® products are an extensive range of UV filters protecting against both UVB and UVA radiation. Some are mostly UVB absorbing, some are mostly UVA absorbing and some have broad band UVB and UVA absorbing properties. The following are currently present in our product portfolio:

Product / INCI name USAN Type of UV absorber appearance solubility Symrise Product# Neo Heliopan® AV Ethylhexyl Methoxycinnamate Octinoxate UVB liquid oil soluble 660523 Neo Heliopan® 303 Octocrylene UVB liquid oil soluble 600154 Neo Heliopan® OS Ethylhexyl Salicylate Octisalate UVB liquid oil soluble 131494 Neo Heliopan® HMS Homosalate UVB liquid oil soluble 182573 Neo Heliopan® E Isoamyl p-Methoxycinnamate UVB liquid oil soluble 1000 656083 Neo Heliopan® MBC Methylbenzylidene Camphor UVB solid oil soluble 600266 Neo Heliopan® Hydro Phenylbenzimidazole Sulfonic UVB solid water soluble 103089 Acid Neo Heliopan® BB Benzophenone-3 UVB and UVA solid oil soluble 116210 Neo Heliopan® AP Disodium Phenyl Dibenzimidazole Bisdisulizole Disodium UVA-II solid water soluble 106796 Tetrasulfonate Neo Heliopan® 357 Butyl Methoxydibenzoylmethane UVA-I solid oil soluble 622501

Neo Heliopan® MA Meradimate UVA-I liquid oil soluble 600096 INORGANIC PIGMENTS

> Zinc Oxide has a long history of use as a skin protectant and has been used in a wide range of dermatological and cosmetic preparations. In addition to its protecting, soothing, healing and antimicrobial properties, zinc oxide effectively scatters and absorbs UV radiation to provide broad band UV protection. It is commonly used in combination with organic UV filters to obtain an optimum level of protection.

> Symrise currently supplies 3 grades of Zinc Oxide, 2 of which are microfine inorganic pigments and the other is a submicron pigment with a primary particle size above 200nm. All of these 3 grades can be used in suncare formulations without incurring an unacceptable whitening effect upon the skin.

> Zinc Oxide Neutral Microfine zinc oxide which has a neutral pH and is USP > Zinc Oxide NDM Zinc Oxide neutral coated with Dimethicone and is USP > Zinc Oxide Pi Sub-micron Zinc Oxide USP LEGISLATION

The use of UV filters in suncare preparations is legislated differently in different parts of the world. In some countries and regions they are regulated as cosmetics via a positive listing as in the EU and Japan. In other countries they are legislated as over the counter drugs as in the USA, Canada and Australia. It is advised that the legal status of each UV filter be checked for each country the finished formulation will be sold in before formulation work starts. This is especially important if global formulations are required. The table below indicates what we believe the legal status of the Neo Heliopan® UV filters with regards to their allowed concentration limits at the time of going to press, since the legislation process in most countries is a dynamic process and these limits are subject to change. Please note that we take no legal responsibility as to the accuracy of this information, it is meant as a guide only. LEGISLATION

Allowed amount in % [1] Asean = Indonesia, Thailand, Malaysia, Vietnam, Cambodia, Laos, Brunai, Darussalam, Myanmar, Philippines, Singapore [2] Allowed to be used alone or in combination with Ethylhexl Methoxycinnamate, , Benzophenones 3 and 4, Ethylhexyl Salicylate, Homosalate and TEA Salicylate