Glossary of Terms COVID-19
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Mathematical Model of the Role of Asymptomatic Infection in Outbreaks of Some Emerging Pathogens
Tropical Medicine and Infectious Disease Article Mathematical Model of the Role of Asymptomatic Infection in Outbreaks of Some Emerging Pathogens Nourridine Siewe 1,* , Bradford Greening, Jr. 2 and Nina H. Fefferman 3 1 School of Mathematical Sciences, Rochester Institute of Technology, College of Sciences, 1 Lomb Memorial Dr, Rochester, NY 14623, USA 2 Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA; [email protected] 3 Department of Ecology and Evolutionary Biology, College of Sciences, The University of Tennessee, 447 Hesler, 569 Dabney Hall, 1416 Circle Dr, Knoxville, TN 37996-1610, USA; [email protected] * Correspondence: [email protected] Received: 1 October 2020; Accepted: 1 December 2020; Published: 9 December 2020 Abstract: Preparation for outbreaks of emerging infectious diseases is often predicated on beliefs that we will be able to understand the epidemiological nature of an outbreak early into its inception. However, since many rare emerging diseases exhibit different epidemiological behaviors from outbreak to outbreak, early and accurate estimation of the epidemiological situation may not be straightforward in all cases. Previous studies have proposed considering the role of active asymptomatic infections co-emerging and co-circulating as part of the process of emergence of a novel pathogen. Thus far, consideration of the role of asymptomatic infections in emerging disease dynamics have usually avoided considering some important sets of influences. In this paper, we present and analyze a mathematical model to explore the hypothetical scenario that some (re)emerging diseases may actually be able to maintain stable, endemic circulation successfully in an entirely asymptomatic state. -
Endo, Backward Contact Tracing, WOR, 2020.Pdf
Wellcome Open Research 2020, 5:239 Last updated: 03 NOV 2020 RESEARCH ARTICLE Implication of backward contact tracing in the presence of overdispersed transmission in COVID-19 outbreaks [version 1; peer review: 2 approved] Akira Endo 1-3, Centre for the Mathematical Modelling of Infectious Diseases COVID-19 Working Group, Quentin J. Leclerc 1,3, Gwenan M. Knight 1,3, Graham F. Medley 3,4, Katherine E. Atkins 1,3,5, Sebastian Funk 1,3, Adam J. Kucharski1,3 1Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK 2The Alan Turing Institute, London, NW1 2DB, UK 3Centre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK 4Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK 5Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH16 4UX, UK v1 First published: 13 Oct 2020, 5:239 Open Peer Review https://doi.org/10.12688/wellcomeopenres.16344.1 Latest published: 13 Oct 2020, 5:239 https://doi.org/10.12688/wellcomeopenres.16344.1 Reviewer Status Abstract Invited Reviewers Introduction: Contact tracing has the potential to control outbreaks without the need for stringent physical distancing policies, e.g. civil 1 2 lockdowns. Unlike forward contact tracing, backward contact tracing identifies the source of newly detected cases. This approach is version 1 particularly valuable when there is high individual-level variation in 13 Oct 2020 report report the number of secondary transmissions (overdispersion). Methods: By using a simple branching process model, we explored 1. -
A Synopsis of the Joint Environment and Human Health Programme in the UK Michael N Moore*1 and Pamela D Kempton2
Environmental Health BioMed Central Introduction Open Access A synopsis of the Joint Environment and Human Health Programme in the UK Michael N Moore*1 and Pamela D Kempton2 Address: 1Plymouth Marine Laboratory, Prospect Place, the Hoe, Plymouth, PL1 3DH, UK and 2Natural Environment Research Council, Polaris House, North Star Avenue, Swindon, SN2 1EU, UK Email: Michael N Moore* - [email protected]; Pamela D Kempton - [email protected] * Corresponding author from Joint Environment and Human Health Programme: Annual Science Day Conference and Workshop Birmingham, UK. 24-25 February 2009 Published: 21 December 2009 Environmental Health 2009, 8(Suppl 1):S1 doi:10.1186/1476-069X-8-S1-S1 <supplement>Sciences Research <title> Council <p>Proceedings (BBSRC), Engineering of the Joint and Environment Physical Sciences and Human Research Health Council Programme: (EPSRC) Annual and Health Science Protection Day Conference Agency (HPAand Work).</note>shop</p> </sponsor> </title> <note>Proceedings</note> <editor>Michael N Moore <url>http://www.biomedcentral.com/content/pdf/1476-069X-8-s1-info.pdf</url>and Pamela D Kempton</editor> <sponsor> <note>Publication of this supplement </sup wasplement> made possible with support from the Natural Environment Research Council (NERC), Environment Agency (EA), Department of the Environment & Rural Affairs (Defra), Ministry of Defence (MOD), Medical Research Council (MRC), The Wellcome Trust, Economic & Social Research Council (ESRC), Biotechnology and Biological This article is available from: http://www.ehjournal.net/content/8/S1/S1 © 2009 Moore and Kempton; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
The Impact on Health of Emissions to Air from Municipal Waste Incinerators
The Impact on Health of Emissions to Air from Municipal Waste Incinerators Advice from the Health Protection Agency RCE-13 The Impact on Health of Emissions to Air from Municipal Waste Incinerators Advice from the Health Protection Agency Documents of the Health Protection Agency Radiation, Chemical and Environmental Hazards February 2010 © Health Protection Agency 2010 Contents The Impact on Health of Emissions to Air from Municipal Waste Incinerators Advice from the Health Protection Agency 1 Summary 1 Introduction 3 Particles 4 Carcinogens 8 Dioxins 9 Epidemiological studies: municipal waste incinerators and cancer 11 Conclusions 11 References 12 Glossary 14 The Impact on Health of Emissions to Air from Municipal Waste Incinerators Advice from the Health Protection Agency Prepared by R L Maynard, H Walton, F Pollitt and R Fielder Summary The Health Protection Agency has reviewed research undertaken to examine the suggested links between emissions from municipal waste incinerators and effects on health. While it is not possible to rule out adverse health effects from modern, well regulated municipal waste incinerators with complete certainty, any potential damage to the health of those living close-by is likely to be very small, if detectable. This view is based on detailed assessments of the effects of air pollutants on health and on the fact that modern and well managed municipal waste incinerators make only a very small contribution to local concentrations of air pollutants. The Committee on Carcinogenicity of Chemicals in Food, Consumer Products and the Environment has reviewed recent data and has concluded that there is no need to change its previous advice, namely that any potential risk of cancer due to residency near to municipal waste incinerators is exceedingly low and probably not measurable by the most modern techniques. -
United Kingdom, the Netherlands and France) in Terms of Epidemiological Response and Preparedness for a Disaster Practicum Dissertation
Environment and health Comparison of three European countries (United Kingdom, the Netherlands and France) in terms of epidemiological response and preparedness for a disaster Practicum Dissertation Marta Sala Soler, Philippe Pirard, Yvon Motreff Summary List of acronyms 2 1. Introduction 4 2. Objective 5 3. Methods 6 3.1 Choice of the material 6 3.2 Bibliographic review 6 3.3 Exchange with other institutes 6 4. Results 7 4.1 Description of the respective epidemiological responses 7 4.2 Comparison points 21 5. Discussion 26 5.1 Health Risk Assessment 27 5.2 Biomonitoring 27 5.3 Community involvement 28 5.4 Epidemiological response 29 5.5 Health Reference Values 33 5.6 Information to population and stakeholders 34 6. Conclusion 35 Bibliography 38 Comparison of three European countries in terms of epidemiological response and preparedness for a disaster — French Institute for Public Health Surveillance Comparison of three European countries (United Kingdom, the Netherlands and France) in terms of epidemiological response and preparedness for a disaster Practicum Dissertation Marta Sala Soler, Philippe Pirard, Yvon Motreff This report was written and presented by Marta Sala Soler, to obtain a second year Master's degree of Public Health (MPH) of the French School of Public Health (EHESP), Rennes. It was part of an internship that took place from February to June 2010 at the French Institute for Public Health (InVS), within the Accidents and Physical Risks Unit of the Environmental Health department. At the InVS, participants to this work -
Dr. John Harrison
Dr. John Harrison Dr. John Harrison is Director of the Public Health England (PHE), Centre for Radiation, Chemical and Environmental Hazards (CRCE) which has headquarters at Chilton, near Didcot in Oxfordshire. Dr. Harrison joined the National Radiological Protection Board (NRPB) in 1974 having gained a B.Sc. in Biochemistry at University College, Wales, and Ph.D. in Biochemistry at St. George's Hospital Medical School, University of London. His doctoral thesis dealt with the biological behaviour of indium and gallium radioisotopes and their use in radiopharmaceuticals. For many years, he was Head of the Radionuclide Effects Group of Radiation Effects Department within NRPB. More recently, he has been Head of Dose Assessments Department and later Deputy Director for Research in the same institute which has a broadened remit as the Centre for Radiation, Chemical and Environmental Hazards (CRCE), first within the Health Protection Agency (HPA) and now part of Public Health England (PHE). Dr. Harrison was a member of the UK Government Committee Examining Radiation Risks of Internal Emitters (CERRIE), which was set up to examine claims that radiation risks from internal emitters are being underestimated by orders of magnitude. He is coordinator of the EU FP7 SOLO project (full title: Epidemiological Studies of Exposed Southern Urals Populations). This project runs until 2015 and is concerned with establishing dose - response relationships for cancer and non-cancer disease induced by radionuclides and external radiation as a result of working at the Russian Mayak plutonium production plant or living near to the Techa River into which radioactive waste was discharged. He is also HPA representative on the Board of the Multidisciplinary European Low Dose Initiative Association (MELODI). -
The Failure of R0
Hindawi Publishing Corporation Computational and Mathematical Methods in Medicine Volume 2011, Article ID 527610, 17 pages doi:10.1155/2011/527610 Review Article The Failure of R0 Jing Li,1 Daniel Blakeley,2 and Robert J. Smith?3 1 Department of Mathematics, Pennsylvania State University, University Park, State College, PA 16802, USA 2 School of Mathematics and Statistics, University of Sheffield, Hicks Building, Hounsfield Road, Sheffield S3 7RH, UK 3 Department of Mathematics and Faculty of Medicine, The University of Ottawa, 585 King Edward Avenue, Ottawa ON, Canada K1N 6N5 Correspondence should be addressed to Robert J. Smith?, [email protected] Received 30 January 2011; Revised 18 May 2011; Accepted 18 May 2011 Academic Editor: Haitao Chu Copyright © 2011 Jing Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The basic reproductive ratio, R0, is one of the fundamental concepts in mathematical biology. It is a threshold parameter, intended to quantify the spread of disease by estimating the average number of secondary infections in a wholly susceptible population, giving an indication of the invasion strength of an epidemic: if R0 < 1, the disease dies out, whereas if R0 > 1, the disease persists. R0 has been widely used as a measure of disease strength to estimate the effectiveness of control measures and to form the backbone of disease-management policy. However, in almost every aspect that matters, R0 is flawed. Diseases can persist with R0 < 1, while diseases with R0 > 1 can die out. -
Acronym Buster
Acronym buster This A–Z is designed to help you translate the array of acronyms used in the pharmaceutical industry. ABHI Association of the British Healthcare Industries ACD Appraisal Consultation Document ADTC Area Drug and Therapeutics Committee (Scotland) AE Adverse Event ADR Adverse Drug Reaction AESGP Association of the European Self Medication Industry AGNSS Advisory Group for National Specialised Services AHSC Academic Health Science Centre ANSN Academic Health Science Network AL Adaptive Licensing AMRC Association of the Medical Research Charities AMS Academy of Medical Sciences APG American Pharmaceutical Group APPG All Party Parliamentary Group/All Party Pharmacy Group AQF Annual Quality Framework (health – Wales) AQP Any Qualified Provider WACG All Wales Cancer Drugs Group (supports the AWMSG) AWMSG All Wales Medicines Strategy Group (HTA body for Wales) AWPAG All Wales Prescribing Advisory Group (subgroup of AWMSG) BAEPD British Association of European Pharmaceutical Distributors BAPW British Association of Pharmaceutical Wholesalers BBSRC Biotechnology and Biological Sciences Research Council BGMA British Generic Manufacturers Association BHBIA British Healthcare Business Intelligence Association BIA BioIndustry Association BIG Bioindustrial Innovation and Growth Team (BIS subgroup) BIS Department for Business, Innovation & Skills BMA British Medical Association BNF British National Formulary BNFC British National Formulary for Children BIVDA British In Vitro Diagnostics Association BPG British Pharma Group CAMHS Child and -
UK Health Protection Agency
WHO International EMF Project IAC Meeting 06-07 June 2013 Report from Public Health England Public Health England is the new expert national public health agency which fulfils the English Secretary of State for Health’s statutory duty to protect health and address inequalities, and executes his power to promote the health and wellbeing of the nation. The radiation protection functions of the former Health Protection Agency (HPA) have moved to PHE and remain UK-wide in scope. PHE has operational autonomy. It has an Advisory Board with a non-executive Chairman and non-executive members. The Centre for Radiation, Chemical and Environmental Hazards is the focus of PHE’s expertise on ionising and non-ionising radiations. It undertakes research to advance knowledge about protection from the risks of these radiations; provides laboratory and technical services; runs training courses; provides expert information and has a significant advisory role in the UK. PHE has a new website (www.gov.uk/phe), which is part of a unified website that is being developed to bring together information and services from across UK Government organisations. PHE has taken responsibility for the web material previously available from HPA and has provided a link to it though “Health Protection A to Z” from the PHE homepage while a new repository for advisory material is developed. This report focuses first on recent scientific advice and related policy developments, then on research carried out at PHE and finally on the work of the independent Advisory Group on Non- ionising Radiation (AGNIR), which reports to PHE. 1 Formal advice and policy developments 1.1 Low frequency fields SAGE was a Government supported stakeholder group which has looked at the feasibility of options for reducing exposure to power frequency electric and magnetic fields as part of a precautionary policy. -
PERFECTION, WRETCHED, NORMAL, and NOWHERE: a REGIONAL GEOGRAPHY of AMERICAN TELEVISION SETTINGS by G. Scott Campbell Submitted T
PERFECTION, WRETCHED, NORMAL, AND NOWHERE: A REGIONAL GEOGRAPHY OF AMERICAN TELEVISION SETTINGS BY G. Scott Campbell Submitted to the graduate degree program in Geography and the Graduate Faculty of the University of Kansas in partial fulfillment of the requirements for the degree of Doctor of Philosophy. ______________________________ Chairperson Committee members* _____________________________* _____________________________* _____________________________* _____________________________* Date defended ___________________ The Dissertation Committee for G. Scott Campbell certifies that this is the approved version of the following dissertation: PERFECTION, WRETCHED, NORMAL, AND NOWHERE: A REGIONAL GEOGRAPHY OF AMERICAN TELEVISION SETTINGS Committee: Chairperson* Date approved: ii ABSTRACT Drawing inspiration from numerous place image studies in geography and other social sciences, this dissertation examines the senses of place and regional identity shaped by more than seven hundred American television series that aired from 1947 to 2007. Each state‘s relative share of these programs is described. The geographic themes, patterns, and images from these programs are analyzed, with an emphasis on identity in five American regions: the Mid-Atlantic, New England, the Midwest, the South, and the West. The dissertation concludes with a comparison of television‘s senses of place to those described in previous studies of regional identity. iii For Sue iv CONTENTS List of Tables vi Acknowledgments vii 1. Introduction 1 2. The Mid-Atlantic 28 3. New England 137 4. The Midwest, Part 1: The Great Lakes States 226 5. The Midwest, Part 2: The Trans-Mississippi Midwest 378 6. The South 450 7. The West 527 8. Conclusion 629 Bibliography 664 v LIST OF TABLES 1. Television and Population Shares 25 2. -
Poisonous Mushrooms
POISONOUS MUSHROOMS DR. SURANJANA SARKAR ASSISTANT PROFESSOR IN BOTANY, SURENDRANATH COLLEGE, KOLKATA Dr. Suranjana Sarkar, SNC INTRODUCTION It was difficult not to since eating wild mushrooms and mushroom poisoning seem to be closely related subjects. This is a rather important topic since mushrooms have apparently been gathered for eating throughout the world, for thousands of years, and it is also likely that during that time many people became ill or died when they inadvertently consumed poisonous mushrooms. Because some mushrooms were known to cause death when consumed, they were also known to be used by assassins. Dr. Suranjana Sarkar, SNC Used as Poison in Assassinations and Murders The most famous of all planned murders was that of Emperor Claudius by his fourth wife, Agrippina, The Younger (also his niece!). The story behind this assassination, as well as the political intrigue that was present during this period of the Roman Empire would have made a great mini series or soap opera. Claudius became emperor, in 41 A.D., following the assassination of his nephew Caligula, and married Agrippina, his fourth wife, after disposing of Messalina, his third wife, for adultery. Agrippina came into the marriage with Nero, a son from a previous marriage and wanted him to follow Claudius as emperor. Agrippina persuaded him to adopt her son so that Nero would be in line to become emperor. Once Nero was adopted, Agrippina plotted to kill Claudius, which involved a number of people. Although ClaudiusDr. Suranjana Sarkar,had SNCa son, Brittanicus, by Messalina, and should have succeeded him as emperor, Claudius shielded him from the responsibilities as heir to the throne and promoted Nero as his successor. -
The Health Protection Agency Bill
RESEARCH PAPER 04/47 The Health Protection 17 JUNE 2004 Agency Bill [HL] Bill 99 2003-04 The Health Protection Agency was established on 1 April 2003, as a Special Health Authority under the NHS Act 1977. The aim of the Health Protection Agency Bill is to establish the Agency as a non- departmental public body, incorporating the National Radiological Protection Board and thereby formally bring together all the elements of health protection and emergency planning to provide a comprehensive health protection system. The Health Protection Agency Bill would provide the Agency with a wider range of functions than those presently available to a Special Health Authority. Kate Haire SCIENCE AND ENVIRONMENT SECTION HOUSE OF COMMONS LIBRARY Recent Library Research Papers include: 04/31 Individual ministerial responsibilities – issues and examples 05.04.04 04/32 Unemployment by Constituency, March 2004 16.04.04 04/33 The Human Rights Clause in the EU's External Agreements 16.04.04 04/34 Age-Related Payments Bill [Bill 92 of 2003-04] 29.04.04 04/35 Economic Indicators [includes article: Offshoring] 04.05.04 04/36 The Energy Bill [HL] [Bill 93 of 2003-04] 06.05.04 04/37 The Nuclear Decommissioning Authority: Part 2 of the Energy Bill [HL] 06.05.04 [Bill 93 of 2003-04] 04/38 Election Timetables 04.05.04 04/39 Unemployment by Constituency, April 2004 12.05.04 04/40 Parliamentary pay and allowances 18.05.04 04/41 The Patents Bill [HL] [Bill 90 of 2003-04] 03.06.04 04/42 Social Indicators [includes article: Summer Olympic Games: Facts 07.06.04 and Figures