Academic Introduction to Professor Huangxian Ju April 30, 2020

Huangxian Ju, male, born on Nov.10, 1964 in Jiangsu, married, is a Changjiang Scholar Professor of chemistry, and Director of State Key Laboratory of Analytical Chemistry for Life Science in Nanjing University

Open Researcher and Contributor Identifier (ORCID): 0000-0002-6741-5302

Address: Department of Chemistry, Nanjing University, Nanjing 210023, P.R.China; E-mail: [email protected]; Tel: 86-25-89683593 (O); Fax: 86-25-89683593. Website: http://sklac.nju.edu.cn/hxju & English edition at http://sklac.nju.edu.cn/hxju/english/english.htm

Summery of Research Works in Huangxain Ju’s Group in 1997-2016： This group is focusing their research on bioanalysis by signal amplification for interface behavior study and signal extraction, molecular recognition and their interaction, detection and tracing of biomolecules. In 1997 this group as one of the earliest groups introduced nanotechnology to biosensing field, and then proposed a series of novel methods for studying the direct electrochemistry of proteins and preparing novel electrochemical biosensors, which have been extensively applied and cited. In 2000 this group combined for the first time PCR technology with electroanalytical chemistry and prepared several highly sensitive DNA biosensors. They then developed the electrochemical cytosensing field, presented the methods for exogenous effect study of cell viability and electrochemical antitumor drug sensitivity test, and proposed the first ECL biosensor based on quantum dots for the first application in bioanalysis in 2003-2005. In 2005-2008 they presented five strategies for chemiluminescent multiplex immunoassay. After 2007, they presented a new ECL mechanism based on the energy transfer of quantum dots for sensitive biosensing and proposed a creative method for fracture sampling on silicone/quartz capillary microchip, designed a method for facile synthesis of highly luminescent CdTe QDs in aqueous solution and tried to develop some protocols for in-situ monoring of cell surface carbohydrates. Since 2010, this group has designed a series of nanotheranostics for photodynamic therapy and real-time therapeutic monitoring of tumors, and signal amplification strategies with nanotechnologies and molecular biological technologies for sensitive detection of small biomolecules, proteins (tumor markers), genes (DNA and RNA), tumor cells and the carbohydrate sites on cell surfaces and for in situ analysis and function studies of intracellular functional species such as microRNA, carbohydrates, telomerase et al. by electrochemical, optical, mass spectrometric, and imaging analysis. The current research fields in this group include bioanalytical chemistry, biosensors and chips, nanobiotechnology and molecular diagnosis. The main contributions of this group can be summarized as follows: 1) Nanobiotechnology and nanoanalysis. Since this group as one of the earliest groups introduced nanotechnology to biosensing field in 1997, a series of signal amplification strategies based on functional nanomaterials have been designed for biosensing (Chem Soc. Rev. 2012, 41, 2122). Several novel nanocomposites, nanoparticles films, nanocage, conductive ormosil materials, functionalized ordered nanoporous silica and protein-nanoparticles architecture were prepared for preparation of novel biosensors (Anal. Chem. 2002, 74, 3579; Adv. Mater. 2004, 16, 1189; Adv. Mater. 2006, 18, 1838; Adv. Funct. Mater. 2007, 17, 585). These materials greatly improve the performance of biosensors for different biomolecules. Two facile methods for preparation of surface protein-imprinted nanowires and nanoparticles were developed for protein specific recognition (Adv. Funct. Mater. 2007, 17, 3223; Anal. Chem. 2009, 81, 9651). Recently, this group prepared several cell-specific nanoparticle for highly selective near- infrared photodynamic therapy against cancer (J. Am. Chem. Soc. 2013, 135, 18850; Angew. Chem. Int. Ed. 2014, 53, 9544; Chem. Sci. 2015, 6, 5969) and cell-subtype specific siRNA delivery (Nat. Commuun. 2016, 7, 13580). 2) Immunosensing and protein analysis. They widened the application of immunoassay by preparing a series of novel amperometric immunosensors and their arrays as well as an instrument for development of new immunoassay

and clinic diagnostic methods (Anal. Chem. 2003, 75, 5429; Clin. Chem. 2007, 53, 1495; Clin. Chem. 2008, 54, 1481; Adv. Funct. Mater. 2011, 21, 2938; Anal. Chem. 2013, 85, 6505; Anal. Chem. 2014, 86, 7494; Anal. Chem. 2016, 88, 9856). Especially, an electric field-driven strategy, two accelerating strategies for fast multiplexed detection of protein biomarkers (Anal. Chem. 2008, 80, 6072; Anal. Chem. 2009, 81, 4043), four new resolution strategies for chemiluminescent multiplex immunoassay and several relevant detection systems were presented for early screening of tumors (Anal. Chem. 2006, 78, 6999; Adv. Funct. Mater. 2008, 18, 3991; Anal. Chem. 2009, 81, 5484; Anal. Chem. 2012, 84, 2410, Anal. Chem. 2014, 86, 5573; Chem. Sci. 2015, 6, 2602). This group also developed for the first time the quantitative methods for MALDI-TOF mass spectrometric detection of peptide and protease activity (Anal. Chem. 2014, 86, 8275; Anal. Chem. 2015, 87, 4409) and designed a chip for mass spectroscopic patterning of caspase activities (Angew. Chem. Int. Ed. 2016, 55, 6667). 3) Cytosensing and in situ detection of functional biomolecules. Several novel protocols based on a surface- confined carbohydrate strategy (J. Am. Chem. Soc. 2008, 130, 7224), cytosensor array (Angew. Chem. Int. Ed. 2009, 48, 6465; Anal. Chem. 2010, 82, 5804; Anal. Chem. 2012, 84, 1452) and signal amplification strategies for convenient in situ evaluation of cell surface carbohydrate sites of interest and protein-specific glycosylation information were presented (Chem. Sci. 2015, 6, 3769; Chem. Sci. 2016, 7, 569; Angew. Chem. Int. Ed. 2016, 55, 5220). The representative work was reviewed as founding work for this field by Dr Strano from MIT (Acc. Chem. Res. 2014, 47, 979). A series of methods for monitoring of cell adhesion, exogenous effect study of cell viability and electrochemical antitumor drug sensitivity test were developed. A method for highly sensitive detection of circulating tumor cells was developed (Clin. Cancer Res. 2007, 13, 2992). The in situ detection methods for intracellular microRNA, telomerase, sialyltransferase activity and caspase family were proposed (Angew. Chem. Int. Ed. 2012, 51, 4607, J. Am. Chem. Soc. 2013, 135, 13282; J. Am. Chem. Soc. 2014, 136, 8205; Sci. Rep. 2015, 5, 10947; Chem. Sci. 2015, 6, 3365). 4) Bioanalysis based on electrochemiluminescence of quantum dots. Their works brought a new field in biosensing application of quantum dots. The first ECL sensor for H2O2 (Anal. Chem. 2004, 76, 6871) and the first ECL biosensor for glucose (Chem. Commun. 2007, 404) based on the intrinsic ECL emission of quantum dots were proposed. An electrogenerated precursor was firstly designed for facile synthesis of highly luminescent QDs in aqueous solution (Chem. Commun. 2008, 450), and several methods for ECL detection of biomolecules, including the first coreactant for extremely sensitive anodic ECL of QDs, were developed (Anal. Chem. 80, 5377-5382 (2008); Chem. Commun. 2010, 4, 404; Chem. Commun. 2013, 49, 2106; Anal. Chem. 2016, 88, 845). New mechnasims, inclusing intermediate annihilation (Anal. Chem. 2007, 79, 6690), the first ECL energy transfer mechanism (Anal. Chem. 2007, 21, 8055), surface unpassivation (Anal. Chem. 2010, 82, 3359), self-produced coreactant (Anal. Chem. 2010, 82, 7351), coreactant consumption (Anal. Chem. 2011, 83, 5214; Anal. Chem. 2013, 85, 5390), electron and energy transfer (Chem. Commun. 2013, 49, 2106), target-induced structure switching (Anal. Chem. 2014, 86, 8735) and ratiometric electrochemiluminescence (Anal. Chem. 2014, 86, 5158) for ECL biosensing and signal amplification have also been proposed. 5) Molecular biological amplification. Some electrochemical hybridization biosensors with detection limits down to 1.7×10-20 mol DNA were designed for detection of short-stranded HBV DNA by combining a PCR procedure at the beginning of this century. By introducing rolling circle amplification (Anal. Chem. 2010, 82, 3337; Anal. Chem. 2012, 84, 7166), target-induced repeated primer extension (Biosens. Bioelectron. 2012, 36, 12), hybridization chain reaction (Anal. Chem. 2013, 85, 11788), target DNA recycling amplification such as endonuclease- (Chem. Eur. J. 2012, 18, 13871; Chem. Commun. 2013, 49, 7561), exonuclease- (Chem. Commun. 2013, 49, 7561) and polymerase- based circular strand-replacement polymerization (Anal. Chem. 2012, 84, 4587; Biosens. Bioelectron. 2013, 39, 199), and assistant DNA recycling (Chem. Commun. 2013, 49, 4006) to amplify the electrochemical, optical and visual signals, this group has established a series methods for convenient and ultrasensitive detections of small biomolecules, proteins, DNA (Chem. Sci. 2015, 6, 4318), RNA and microRNA. This group summarized the functions and detection methods of microRNA (Chem. Rev. 2013, 113, 6207–6233).

Education: B.S. and M.S. in Analytical Chemistry at Nanjing University in July 1986 and July 1989 Ph.D. in Analytical Chemistry at Nanjing University in July 1992. Thesis: Investigation on the Theory and Application of Microelectrode Voltammetry. Supervisors: Professor Hongyuan Chen and Professor Hong Kao, Academicians.

Academic Titles: Professor and Doctoral Adviser from 1999, Associate Professor during 1993-1998 and Lecturer during 1992-1993 at Nanjing University. Fellow of the International Society of Electrochemistry (April 28th, 2015) Fellow of the Royal Society of Chemistry (Sept 25th, 2015) Executive Member in the International Union of Advanced Materials (IUAM) (Aug. 2011- Aug. 2013) Editorial Board Member of Scientific Reports (from May 2015); Editorial Board Member of Electroanalysis (from January 2010); Editorial Board Member of Analytical Letters (from September 2002); Associate Editor (2016- ), Executive Editor (2005-2006), Associate Editor (2003-2005), Asian Editor (2001-2003) and Editorial Board Member for SENSORS at www.mdpi.net/sensors Editorial Board Member of Science China: Chemistry (from October 2006 to 2019); Editorial Board Member of Chinese Journal of Chemistry (from October 2006); Editorial Board Member of Chinese Journal of Analytical Chemistry (from October 2006); Editorial Board Member of American Journal of Biomedical Science & Research (from Feb 2020); Editorial Board Member for Chemosensors at http://www.mdpi.com/journal/chemosensors Chief Editor of Frontiers in Analytical Chemistry (http://www.frontiersin.org) from Nov 8, 2012 Editor-in-Chief of Current Biomarkers from April 8, 2018 Editor-in-Chief of Journal of Sensors and Instrumentation (www.uscip.org) (from January 2012) Associate Editor of Journal of Integrated Omics. A Methodological Journal. www.jiomics.com, from Sept 2012 Associate Editor of Telomere and Telomerase (www.smartscitech.com, from Nov, 2014) Associate Editor of Journal of Analysis and Testing (Springer) June 27, 2016 Associate Editor of The Open Biomarkers Journal (Bentham Open) Aug 20, 2017 Editorial Board Member of Current Trends in Biotechnology Pharmacy (from October 2007); Editorial Board Member of American Journal of Biomedical Sciences (from April 2008); Regional Editor, Current Research Journal of Biological Sciences (from April 21, 2009); Editorial Board Member of World Journal of Gastrointestinal Oncology (2010-2015, 2016-2019); Editorial Board Member of World Journal of Critical Care Medicine (2010-2015, 2016-2019); Editorial Board Member of World Journal of Methodology (WJM) (2011-2015, 2016-2019); Editorial Board Member of World Journal of Clinical Pediatrics (WJCP) (from Feb 10, 2011-2020 Editorial Board Member of SRX Chemistry (from January 2010); Editorial Board member of Current Chemical Research (from January 2010) Editorial Board member of Research and Reports in Medicinal Chemistry (from July 2011) Honorary Editorial Board member of Nanobiosensors in Disease Diagnosis (from Sept 8 2011) Editorial Board member of Inter. J. Biotechnol. Biochem. (IJBB) (from May 10, 2012) Editorial Board member of Journal of Biochips & Tissue Chips (from May 2012) Editorial Board member of Advanced Electrochemistry (http://www.aspbs.com/adel/, from May 2012) Editorial Board member of Chemosensors www.mdpi.com/journal/chemosensors (from July 4, 2012) Editorial Board member of Journal of Tumor (from Dec 2013) Academic Editor of American Chemical Science Journal www.sciencedomain.org (from March 7, 2013) Editorial Board member of American Journal of Biosensors & Bioelectronics (from Feb 14, 2014) Editorial Board member of Austin J. Anal. Pharmac. Chem. (from May 9, 2014) Editorial Board member of Int. J. Med. Nano Res. (http://clinmedlibrary.com/) from Jan 15, 2015) Editorial Board member of Pharm. Anal. Chem. http://www.omicsonline.org/ from Aug 20, 2015 Editorial Board member of Dual Diagnosis: Open Access at dual-diagnosis.imedpub.com from Sept 1, 2015 Editorial Board member of Science Today, www.lognor.com from Nov 1, 2015 Editorial Board for Journal of Imaging Science (JIS) www.ommegaonline.org from June 29, 2016 Editorial Board member of Canadian J. Biotechnol., www.higherstudiescounseling.com from Sept. 10, 2016 Editorial Advisory Board of Current Bionanotechnology, www.benthamscience.com/journals/current- bionanotechnology/ from March 10, 2017 Editorial Advisory Board of Am J Nanotechnol Nanomed, http://www.scireslit.com/Nanotechnology Feb 2018 Editorial Board member of Accounts of Anal. Chem. Res. The Am Publishing house HOUSE June 19 2018

Editorial Board member of The Open Biomarkers Journal https://twitter.com/bentham_open Oct 25 2018 Editorial Board member of Oncology Research: Open Access https://app.getresponse.com/ Aug 27 2018 Editorial Board member of Gazette of Cancer Biology and Toxicology Nov 25 2019 Advisory board member, Sensors International Editorial Board Member of Acta Pharmaceutia Sinica (from March 2003); Editorial Board Member of Chinese Journal of Analytical Science (from 1999); Editorial Board Member of Chinese Journal of Analysis Laboratory (from October 2004); Editorial Board Member of Chemical Sensors (from October 2005); Editorial Board Member of Chinese Journal of Surgical Oncology (from January 2009) Editorial Board Member of Chinese Journal of Instrumental Analysis (from April 2010); Editorial Board Member of Chinese Journal of Inorganic and Analytical Chemistry (from Dec. 2010) Editorial Board Member of International Journal of Biotechnology & Biochemistry (IJBB) (Mar 2010) Honorary Editorial Board Member of Acta Pharmaceutica Sinica B (from June 2011) Director of Electroanalytical Chemistry Committee, Chinese Society of Instruments (from 2007); Director of Analytical Chemistry Committee, Chemistry Society of Jiangsu Province (from 2003); Vice Director of Analytical Chemistry Discipline, Chinese Chemical Society (from 2011); Vice Director of Organic Analysis Committee, Chinese Chemical Society (from 2011); Vice Chairman Member, Analytical Instruments Society, Chinese Society of Instruments (from 2018); Vice Director of Chemical Sensors Committee, Chinese Society of Instruments (from 2005); Member of Chemical Biology Committee, Chinese Chemical Society (from 2011); Vice Chairman Member of Jiangsu Province Association for Instrumental Analysis (from 2011); Vice Director of Young Academic Committee of Chinese Association for Instrumental Analysis (2003-2011); Vice Director of Biosensor-Biochip-Nanobiotechnology Committee, China Society of Bioengineering(from 2017); Vice Director of Committee of Analytical Pharmacology, Chinese Pharmacological Society (from 2017); Vice Chairman of the Strategic Alliance for Technological Innovation in the Bioassay Monitoring Industry, China Association for the Promotion of Industry-University-Research Cooperation Director of Mass Spectroscopy Committee, Chemistry Society of Jiangsu Province (from 2018); Adjunct Professor and Doctoral Adviser of Chongqing Medical University (from 2002); Adjunct Professor of Nanjing University of Technology (from 2008-2010); Adjunct Professor of Liaocheng University (from 2000-2002). Adjunct Professor of Hubei Normal University (2003-2008). Adjunct Professor of Hainan Medical University (from 2018) Adjunct Professor of Jinan University (from 2018)

Experience: 1) Director of State Key Laboratory of Analytical Chemistry for Life Science from 2011 2) Vice director of Modern Analytical Center of Nanjing University, from July, 2008 3) Director of Key Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China) from February, 2009, and vice director of this laboratory from September, 2008 4) Director of Analytical Chemistry Division, 1999-2005 5) Leader of a Creative Research Group of National Nature Science Foundation Committee (2006-2011) 6) Executive Chairman of the 11th Asian Conference on Analytical Sciences (2011); the 7th Sino- French Workshop on “Surface Electrochemistry of Molecules of Biological Interest & Biosensor Applications” (2011), the 2nd Symposium of Asian Analytical Chemistry Network (2011), Chairman of the 5th Nanjing University –Hokkaido University Joint Symposium---Progress in Advanced Chemistry (2009); Executive Chairman of International Symposium on Sensor Sciences, May 28-June 2, 2004 7) Executive Chairman of the 7th National Conference on Chemical Biology (2011), the Ninth National Conference on Electroanalytical Chemistry (2005); the 7th National Youth Conference on Instrumental Analysis (2002) 8) Member of Advisory Panel of 1st Regional Electrochemistry Meeting of South-East Asia (REMSEA 2008) (Singapore, 2008) 9) Member of Scientific Advisory Board of 2003 International Symposium on Sensor Sciences (Paris, 2003) 10) Guest Professor, Institute of Biochemistry and Biology, University of Potsdam (Germany), June - July 2000

11) Guest Scientist, Institute of Chemical and Biosensors, University of Muenster (Germany), July - August 2000 12) Visiting Professor, National University of Ireland, Galway (Ireland), Nov. - Dec. 1999 13) Postdoctoral researcher, Montreal University (Canada), Jan.1996 - July 1997 14) As a Tin Ka Ping Foundation-HKBU Mainland China Visiting Scholar to visit Hong Kong Baptist University, September, 24-28, 2010 Research Projects and Funds: A) Currently (1) As the leader of a key program in “Novel methods forin situ and in vivo analysis of functional biomolecules and cancer precision diagnosis and accurate therapy mediated by these molecules” supported by the NNSFC, 2016-2020 (3,000,000 Yuan) (2) As the leader of a National Major Research and Development Project of Scientific Instruments in “Microfluidic Device for Visual Screening of Specific Antibodies” supported by the NNSFC, 2019-2023 (7,800,000 Yuan) (3) As the leader of a topic of major project in “Precise Measurement of Tumor Markers and Their Molecular Mechanisms: Multimodal, Multilevel Measurement and Imaging of Tumor Markers” supported by the NNSFC, 2019-2023 (4,500,000 Yuan) (4) National Key Research and Development Program of China in “Study on the interaction between metabolic intermediates and sensory proteins and the structural changes of sensory proteins” supported by the Ministry of Science and Technology, 2019-2021 (1,400,000 Yuan) B) Previously (36) (3,000,000 Yuan) (35) “The application of organic electrochemical transistors as a state-of-the-art platform for label-free, ultrasensitive, high throughput and portable nucleic acid detection” supported by the NNSFC, 2014-2017 (800,000 Yuan) (34) Research Foundation for the Doctoral Program of Higher Education of China, supported by the Ministry of Education of China (20130091130005), 2015-2017 (400,000 Yuan) (33) “New electrochemical analytical methods and in situ and portable detection systems for heavy metals” supported by Ministry of Science and Technology, 2012-2016 (6,700,000 Yuan) (32) “Function and Application of Glycosyltransferase” supported by the project of the major research plan, NNSFC, 2015 (500,000 Yuan) (31) As a Chief Scientist of a National Basic Research Program of China: “Basic Research on Bionic Molecular Recognition and Its Application in Biomedicine” (No.2010CB732400), 2010-2014 (30,020,000 Yuan, 7,700,000 Yuan for Ju’s Group ) (30) As the head of the National Science Funds for Creative Research Groups in “New theory, methods, and technology of analytical chemistry in life sciences” supported by the NNSFC, 2006-2008， 2009-2011，2012-2014 (4,200,000，5,000,000，6,000,000 Yuan，respectively) (29) “Regulation and control of some sugar chain-mediated recognition processes in cells --- Highly selective detection and function of sugar chains in cells” supported by the project of the major research plan, NNSFC, 2012-2015 (1,350,000 Yuan) (28) “Highly selective detection of glycosyls and their interactions with small chemical molecules as well as signal transduction” supported by the NNSFC 2008 to 2010 as a major research plan (500,000 Yuan) (27) “Highly sensitive electrochemical biosensors for the detection of DNA hybridization” supported by the NNSFC for an international cooperation between NNSFC and DEST from 2008 to 2010, (90, 000 Yuan) (26) “New Platform for Clinic diagnosis, in situ screening and fast assay of tuberculosis based on DNA biosensing” supported by Ministry of Science and Technology from 2009 to 2010 (1,800,000 Yuan) (25) As the leader of a key program in “New methods and technology for molecular diagnoses” supported by the NNSFC, 2006-2009 (1,900,000 Yuan) (24) As one member of an 863 program in “Chips and devices for forensic poison detection” supported by the Ministry of Science and Technology of China, 2007-2009 (23) As the leader of the National Science Funds for Creative Research Groups in “New theory, methods, and technology of analytical chemistry in life sciences” supported by the NNSFC, 2006- 2008 (4,200,000 Yuan)

(22) “Novel methods of immunoassay and high throughput chip techniques” supported by the NNSFC for National Outstanding Young Scientists, 2004-2007 (21) As one member of an 863 program in “Detection chips and devices for illicit drugs” supported by the Ministry of Science and Technology of China, 2007-2008 (20) As the leader of a creative project supported by Nanjing University, 2007 (760,000 Yuan) (19) “Immune detection techniques of proteins on tumor cells” for Excellent Young Teachers from Chinese Ministry of Education from 2003 to 2005 (18) “Study on the clinic significance and novel detection techniques of immune expression on tumor cells” supported by NNSFC from 2003 to 2005 (17) “Genetic and immunoassay of virus for diagnoses of SARS and diseases” supported by both NNSFC and Nanjing University in 2003 (16) As one co-leader of a key program in molecular diagnoses and cure of breast cancer supported by Jiangsu Province, 2006-2008 (15) As one co-leader of a program in chip diagnosis technique supported by Jiangsu Province, 2006- 2008 (14) “Study on the novel techniques of online and chip immunoassay for multicomponents of tumor markers” supported by both Jiangsu Province and Cancer Hospital and Institute of Jiangsu Province from 2002 to 2005. (13) “Electrochemical biosensors” supported by the Specialized Research Fund for the Doctoral Program of Higher Education from Ministry of Education of China from 2001-2003 (12) “Development of novel electrochemical instruments” supported by Electroanalytical Instrument Company of Jiangsu from 2001 to 2004 (11) “Template recognition of nucleic acid and PCR amplification and their electrochemical gene devices for pathogen assays” supported by NNSFC from 2000 to 2002 (10) “PCR amplification and their electrochemical gene devices for pathogen assays” supported by the Opening Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry from 2001 to 2002 (9) “Electrochemical biosensors” supported by the Ministry of Education of China for Main Young Teachers from 1999-2001 (8) “Surface electrochemistry and pathogen gene electrochemical devices” supported by both Jiangsu Province and Nanjing city Government from 1999 to 2001, respectively (7) “Surface electrochemistry and electrochemical biosensors” supported by the State Key Laboratory in 1999-2001 and 2002-2003, respectively (6) “Development of electrochemical instruments” supported by Electroanalytical Instruments Company of Jiangsu from 2000-2004. (5) Two projects in bioelectrochemistry and biosensors supported by NNSFC and the State Education Committee of China from 1994 to 1996 and 1997 to 1999 (4) One international cooperation project between National University of Ireland and my group supported by NNSFC from 2001 to 2002. (3) One international cooperation project between Nantes University and my group supported by NNSFC in 2005. (2) Participating in one key project supported by the NNSFC from 2003-2004 (1) Have participated in five projects (including two important projects) in 1990-1996 and one key project from 1998 to 2002, supported by the NNSFC. Teaching and Postgraduates (1) My current group includes 4 professors and 2 associate professors, 2 research assistants, 1 postdocs, 35 doctoral students and 19 master students. (2) Have guided the works of 60 undergraduates, 51 postgraduates and 65 doctoral students, 14 postdoctoral researcher, and 10 visiting scholars (3) "Fundamental of Electroanalytical Chemistry", a course of postgraduate, 1997 – 2008 (4) "Analytical Biochemistry", a course of postgraduate, 2002 – now (5) "Modern Electrochemistry" a course of postgraduate in 1994-1995 and 1998 (6) "Experiments in Analytical Chemistry and Instrumental Analysis", 1992-1999 (7) “Chemistry and Life”, 2009-

Honors: 35) “Winner of National Fund for Outstanding Young Scholars”, awarded by NNSFC in 2003.

34) Changjiang Scholar Professor appointed by Education Ministry of China in 2007 33) China's First Leici Outstanding Achievement Award for Chemical Sensors in 2019 32) Taishan Scholar Professor appointed by Shandong Province China in 2017 31) ISE Fellows, appointed on April 28, 2015, RSC Fellows, appointed on Nov. 6, 2015 30) National Key Talents in The New Century in 2007 29) Chief Scientist of National Key Basic Research Program, appointed by MST in 2009 28) "Scientific and Technological Prize" from Chongqing City Government in 2017 27) "Scientific and Technological Prize" from Jiangsu Province Government in 2018. 26) "Scientific and Technological Prize" from Jiangsu Province Government in 2016. 25) "Scientific and Technological Prize" as a co-worker from Jiangsu Province Government in 2015. 24) "Scientific and Technological Prize" as a co-worker from Jiangsu Province Government in 2014. 23) "Scientific and Technological Prize" by Chinese Association for Instrumental Analysis in 2014. 22) "Natural Science Prize in Chinese Universities" by Education Ministry of China in 2013. 21) “Excellent Scientists” by Scientist Association of Jiangsu Province in 2012 20) “Person of the Year in 2010 Science Chinese” received in 2011 19) "Scientific and Technological Prize" as a co-worker from Jiangsu Province Government in 2010. 18) "Natural Science Prize in Chinese Universities" by Education Ministry of China in 2009. 17) "Scientific and Technological Progress Prize" from Jiangsu Province Government in 2009. 16) "Scientific and Technological Prize" by Chinese Association for Instrumental Analysis in 2009. 15) "Liang Shuquan Award for Basic Research in Anal. Chem." by Chinese Chemical Society in 2009. 14) "Outstanding Young Scientist Award", awarded by Jiangsu Province Government in 2001. 13) “Scientific and Technological Progress Prize” by Jiangsu Province Government in 2008. 12) “Scientific and Technological Prize” by Chinese Association for Instrumental Analysis in 2008. 11) “Award for New Techniques” by Board of Health of Jiangsu Province in 2008. 10) “Scientific and Technological Progress Prize” by Nanjing City Government in 2007 9) “Award for New Techniques” by Board of Health of Jiangsu Province in 2005 8) “Natural Science Award in Chinese Universities” by Education Ministry of China in 2000. 7) "Scientific and Technological Progress Prize" from Education Ministry of China in 1998. 6) "Scientific and Technological Progress Prize" from the State Education Committee in 1995. 5) “Journals Grants for International Authors” from The Royal Society of Chemistry, 1999. 4) "Young Chemists Award", awarded by Chinese Chemical Society in 1996 3) "1999’s, 1998’s and 1995’s Young Teacher Award for Scientific Researches", awarded by Nanjing University in 1999, 1998 and 1995, respectively. 2) "Young Teacher Ying Song Prize", awarded by Nanjing University in 1993. 1) "Guang Hua Prize", twice awarded by Nanjing University in 1990 and 1991.

Research Fields: Current research interests are in bioanalytical chemistry, molecular diagnosis, biosensors and chips, clinic immunoassay, celluar analytical chemistry, bionanotechnology, electroanalysis, luminescence analysis, mass spectroscopy, and capillary electrophoresis. Research fields include: 1) Analytical Biochemistry and Electroanalytical Chemistry: immunoassay, genetic detection, clinic detection techniques of tumor markers, voltammetric analysis, microdevices, lab-on-chip; fluorescent analysis, chemiluminescence, electrochemiluminescence, capillary electrophoresis, mass spectroscopy, bioconjugate chemistry; 2) Electrochemistry: mechanism of electrode process; self-assembled monolayers, bioelectrochemistry, microelectrodes and arrays, chemically modified electrodes, surface electrochemistry; applied electrochemistry; 3) Biosensors: biosensors, microbiosensors, immunosensors, cytosensors, multiplexed immunosensing; etc. 4) Nanotechnology: functional nanomaterials; molecularly imprinting; layer-by-layer assembly; nanocomposites; hybrid nanoparticles; nanocage; quantum dots; etc.

Group members: Current group includes 63 members: Dr. Huangxian Ju (Professor), Dr. Jianping Lei (Professor), Dr. Ying Liu (Professor), Dr. Jie Wu (Associate Professor), Dr. Lin Ding (Professor), Dr. Jun Zhou (Associate Professor), and Miss Ai Liu (7) Research assistants (2): Dr Yunlong Chen, Dr Weiwei Chen

Ph.D students (35): Xiaobo Zhang, Zhihao Zhong, Jielin Chen, Liangsheng Kong Nan Feng, Huipu Liu, Shijiong Wei, Guangming Li (8) Miss Yue Zhang, Lizhen Chen, Ningning Wang, Xiaoyan Zhou, Siqi Yu, Yuanjiao Yang, Hang Ao, Hongying Jia, Qian Yu, Qingqing Tan, Ying An (11) Co-advisor: Fang Wang, Yuanyuan Huang, Yuna Guo, Yulin He, Yiran Li, Cong Tang, Yanyun Fang, Rengan Lou, Guyu Wang, Yingfei Wang, Chen Yang, Minhao Fu, Yihong Zhong, Yunyan Yao, Hongxia Zhao, Shiyi Bi (16) Master students (19): Chengtao Chen (1) Miss Qiulin Ma, Linfei Xiong Hui Ding (3) Co-advisor: Jin Huang, Jin Tao, Xiaofeng Yu, Pengyun Dang, Yuyi Li, Yue Zhang, Yi Man, Zhengqing He, Hao Xiin, Zhongchao Jin, Pengfei Dong, Anwen Mao, Huifang Shi, Jinling Fu, Jiaojiao Wang (15) Previous 190 members: Visit Scholars (10): Mr. Jingan Ni, Songqin Liu, Jun Wang, Jin Zhang, Mrs Xilan Cai, Xiaoxing Xu, Shuizhen Zong, Changrong Zhao, Suxing Luo, Juan Wei Postdoc. & RA (14): Dr. Sichun Zhang, Vivek Babu Kandimalla, V.S.Tripathi, Hui Jiang, Cunwang Ge, Faten Divsar, Guangming Wen, Yinhua Yan, Lei Zhang, Changfeng Li, Kewei Ren, Akanda, Jayakumar, Jianshe Tang Ph.D students for Prof. Hongyuan Chen (4): Chenxin Cai, Dongmei Zhou, Huaisheng Wang, Miss Yi Xiao Ph.D students (65): Mr. Jiuhing Yu, Songqin Liu, Guanghua Zhu, Yongkang Ye, Daming Zhang, Zong Dai, Yong Cao, Guizhen Zhou; Jianguo Li, Jin Chen, Cheng Hao, Zhifeng Fu, Zhian Liu, Zhanjun Yang, Chun Zhai, Yadong Xue, Wenwen Tu, Wei Cheng, Haifeng Dong Guosong Lai, En Han, Shenyuan Deng, Rao Geng, Dajie Lin, Fenglei Gao, Jiangwei Tian, Xianjiu Liao, Quanbo Wang, Yunlong Chen, Kewei Ren, Lei Bao, Yongjie Xu, Yuehua Guo, Yaqiang Feng, Tingyuan Lang, Jingxing Guo (35) Miss Yafeng Zhuang, Wei Wei, Zhihui Dai, Jiehua Lin, Li Tan, Dan Du, Lina Wu, Shou Wu, Jie Wu, Ruizhuo Ouyang, Xiaoqing Zhang, Lin Ding, Xuan Liu, Jing Zhang, Ping Qu, Rongna Ma, Ruocan Qian, Chen Zong, Lin Cui, Dandan Li, Aisha Bibi, Junjie Hu, Xiaoyan Zhou (24) Co-advisor: Lei Zhang, Yang Zang, Pinghua Ling, Jintong Liu, Longyi Zhu, Siqiao Li (6) Master students (97) Mr. Yi Gong, Zong Dai, Xiaojun Lu, Yonglin Zhu, Jin Chen, Bin Li, Hongtao Zhao, Yadong Xue, Wenwen Tu, Wei Cheng, Hong Liu, Liang Guo, Shenyuan Deng, Xu Xu, Chuan Leng, Mr. Hanxu Ji, Yunlong Chen, Peng Wang, Jie Li, Wanyao Song, Mr Yawei Wang (21) Miss Ling Dong, Jiayin Gu, Baofeng Ye, Hua Yu, Lina Wu, Jing Chen, Jie Wu, Fengjuan Zhao, Lin Ding, Ying Liu, Fang Tan, Xuan Liu, Min Xu, Wei Qiang, Juan You, Yiying Liu, Linxiao Cheng, Jin Sheng, Chen Zong, Ruocan Qian, Chen Wang, Zhu Zhu, Yueting Liu, Junjie Hu, Miaoqi Li, Feng Sun, Peipei Xu, Jing Zhu, Yingying Xiong, Yingying Zhang (30) Co-advisor: Yuetian Yan, Sheng Tang, Yangyang Zhang, Wenchao Gao, Lei Zhang, Jie Li, Qiunan Xu, Liu Tong, Lisong Wang, Jie Xu, Wenjing Wang, Lin Liu, Yan Cheng, Xiaoping Yu, Yanqiu Ge, Yin Huang, Nan Xu, Yana Li, Li Jia, Qing Hao, Jintong Liu, Mengmeng Liu, Yujie Xie, Na Wu, Liwen Yan, Yuhang Ji, Qianhui Yang, Kaili Yang, Shizhe Fu, Jingjing Hui, Min Huo, Fengjiao Ma, Hong Shen, Qing Xiao, Yimei Feng, Yiran Liu, Xiao Meng, Tingting Yan, Shengbo Liu, Lu Liu, Peiwen Zhang, Haiying Gan, Xueqin Zhang, Lina Wu, Rong He, Juanjuan Li, Minhao Fu (46)

Patents: 1) A vaporous deposition method for preparation of titania sol-gel matrix, ZL 01 1 38059.4 (C23C 16/40), obtained on August 20, 2003 by Huangxian Ju and Jiuhong Yu, No. 119989 2) Preparation and application of a reagentless amperometric immunosensors, ZL 03 1 13053.4 (G01N 27/26), obtained on April 13, 2005 by Feng Yan, Zong Dai and Huangxian Ju，No. 203175 3) Synthesis of immunogen for anti-cruor raticide, ZL 2003 1 0106386.6 (C07K 14/705), obtained on Dec. 28, 2005 by Daming Zhang, Chaoqin Song and Huangxian Ju，No. 242209

4) A flow injection cell for chemiluminescent immunoassay based on silane cross-linkedchitosan membrane and its preparation method, ZL 2004 1 0041176.8, authorized on June 27, 2007 by Feng Yan, Jiehua Lin and Huangxian Ju, No. 332122 5) A method for in situ electrochemical immunoassay of surface antigen by on tumor cell, ZL 2004 1 0064732.3, authorized on April 25, 2007 by Huangxian Ju and Dan Du, No. 321223 6) A method for concentration detection of organophosphorous insecticide, ZL 2005 1 0038059.0 authorized on November 14, 2007 by Huangxian Ju, Vivek Babu Kandimalla and Jin Chen, No. 358336 7) A method of electrochemical immunoassay for cancer makers and a microvolume chip for immunoassay, ZL 2004 1 0041175.3, authorized on Dec 26, 2007 by Zong Dai, Feng Yan, Huangxian Ju, No. 366231 8) Analyzer for electrochemical primary diagnosis and screening of malignant tumor, ZL 2006 2 0073068.3 (new pattern of practical patent, China) authorized on November 14, 2007 by Huangxian Ju, No. 984049 9) Analyzer for electrochemical primary diagnosis and screening of malignant tumor, international application number: PCT/CN2007/001237, published number: WO/2007/124669 (http://www.wipo.int/pctdb/en/ia.jsp?ia=CN2007/001237) by Huangxian Ju. 10) An automated successive sampling device for quantitative liquid, ZL 2007 1 0024843.5 authorized on August 25, 2010 by Hongbin Pan, Huangxian Ju, Jie Wu, Feng Yan, Chun Zhai and Jianping Lei, No. 664670 11) Analyzer for electrochemical primary diagnosis and screening of malignant tumor, 2006 1 0040051.2 (invention patent, China), authorized on March 28, 2012, by Huangxian Ju, No. 927850 12) Multianalyte chemiluminescent immunosensing method and immunoassay system based on substrate zone- resolved technique, ZL 2006 1 0041334.9 (invention patent, China), authorized on Jan. 12, 2011, by Huangxian Ju and Zhifeng Fu, No. 728771 13) Automated channel-resolved chemiluminescent multianalyte immunoassay system and analytical method, ZL 2007 1 0021074.3 (invention patent, China), authorized on August 31, 2011, by Huangxian Ju and Zhifeng Fu., No. 832630 14) Analytical method of mercapto compounds based on electrochemiluminescence of quantum dots, ZL 2007 1 0021007.1 (invention patent, China) authorized on August 31, 2011, by Huangxian Ju and Hui Jiang, No. 832191 15) Synthesis of highly luminescent CdTe quantum dots with cathodic stripping of Te electrode, ZL 2007 1 0134534.3 (invention patent, China), authorized on Oct 9, 2011, by Cunwang Ge, Min Xu and Huangxian Ju, No. 860352 16) Design and fabrication of portable high-effective capillary electrophoresis microchip with fracture sampling, ZL 200710134527.3 (invention patent, China), authorized on Jan 4, 2012, by Huangxian Ju and Chun Zai, No. 891041 17) Automated sampling-resolution chemiluminescent multiplexed immunoassay system and analytical method, ZL 200810024426.5 (invention patent, China), authorized on Jan 8, 2014, by Feng Yan, Hong Liu and Huangxian Ju, No. 1332241 18) Rapid chemiluminescent immunoassay system and analytical method, ZL 200910029449.X (invention patent, China), authorized on May 14, 2014, by Hong Liu, Feng Yan and Huangxian Ju, No. 1404553 19) A quick visual method for detection of copper ion based on quantum photoelectric effect, 201210232537.1 (invention patent, China), applied on July 6, 2012 by Huangxian Ju, Peng Wang Jianping Lei 20) Highly sensitive disposable multiplexed chemiluminescent imaging immunosensors, ZL 201210249219.6 (invention patent, China), authorized on Sept 23, 2015, by Feng Yan, Chen Zong, Jie Wu and Huangxian Ju, No. 1800201 21) A kind of theranostic nanoparticles for breast cancer and its preparation, 201310222239.9 (invention patent, China), applied on June 6, 2013 by Ju Huangxian, Tian Jiangwei, Ding Lin, Yu Junsheng, Shen Zhen 22) A nanoprobe for in situ detection of intracellular telomerase activity and its preparation, ZL 201310256710.6 (invention patent, China), authorized on Nov 9, 2016, by Ju Huangxian, Ding Lin and Qian Ruocan, No. 2290692 23) Highly sensitive and selective electrochemical sensor for mercury cation, 201310513321.7 (invention patent, China), applied on October 28, 2013 by Ju Huangxian, Cui Lin, Wu Jie 24) Ratiometric electrochemical immunosensor based on labelled dual nucleotides, 201410058187.0 (invention patent, China), applied on Feb. 21, 2014 by Ju Huangxian, Yan Feng, Ren Kewei Wu Jie 25) Homogeneous chemiluminescence immunoassay method based on proximity effect, ZL 201410190726.6 (invention patent, China), authorized on Aug 7, 2018, by Ju Huangxian, Yan Feng, Chen Zong, Wu Jie

26) A nanoprobe for in situ imaging of intracellular telomerase activity and its preparation, 201410193997.7 (invention patent, China), applied on May 9, 2014 by Ju Huangxian, Ding Lin, Qian Ruocan 27) Ratiometric electrochemical immunosensor based on labelled dual nucleotides, 201410623931.7 (invention patent, China), applied on Nov. 10, 2014 by Ju Ju Huangxian,Yan Feng, Ren Kewei, Wu Jie 28) A high throughput photoelectric colorimetric method for detection of copper ion, 201710224147.2 (invention patent, China), applied on April 7, 2017 by Lei Jianping, Yang Qianhui, Hao Qing, Ju Huangxian 29) A homogeneous immunoassay based on target-induced cyclic DNAzyme formation, 201710234646.X (invention patent, China), applied on April 27, 2017 by Wu Jie, Ju Huangxian, Yang Kaili 30) A flexible 2D device for Raman quantifying and mapping and its preparation, 201410623931.7 (invention patent, China), applied on May 23, 2017 by Ju Huangxian, Guo Jingxing, Chen Yunlong 31) A nano-amplicon comparator for live cell microRNA imaging as well as its preparation method， 201710445317.X，Lin Ding, Huangxian Ju, Min Huo, June 9, 2017 32) A thermophilic tetramolecular G-quadruplex/hemin DNAzyme, 201710491309 .9, Jun Zhou, Huangxian Ju, Yuehua Guo, Jielin Chen, June 21, 2017 33) A method for preparation of thermoresponsive polymer arrays and it application in sample pretreatment, 201710512030.4, Ying Liu, Huangxian Ju, Xiao Men, June 28, 2017 34) A couple of micro-bubble probes for quantitative screening of gangliosides on cell surface and their preparation, 201711272434.7 Huangxian Ju, Yunlong Chen, Huipu Liu, Xingying Xiong, Dec 1, 2017 35) A chemiluminescence imaging method for protein based on DNA microarray, 201810429351.2, Jie Wu, Huangxian Ju, Qin Xiao, May 2, 2018

Monographs in English: 1) Xueji Zhang, Huangxian Ju, Joseph Wang (Editors), 《Electrochemical Sensors, Biosensors and Their Biomedical Applications》, Academic Press (Elsevier Inc.), November 2007 (English) 2) Huangxian Ju, Xueji Zhang, Joseph Wang (Authors), 《NanoBiosensing — Principles, Development and Application》, Springer, August 1, 2011 (English) 3) Huangxian Ju, Guosong Lai, Feng Yan (Authors), 《 Immunosensing for Detection of Protein Biomarkers》, Elsevier Inc., May 2017 (English) 4) Huangxian Ju, Bo Tang, Lin Ding (Authors), 《In Situ Analysis of Cellular Functional Molecules》, Royal Society of Chemistry, pp1-253, Jan 14, 2020 https://doi.org/10.1039/9781839160455 (English) 5) Huangxian Ju, 《Electrochemical Sensor》, World Scientific Publishing Co Pte Ltd, 2020 (English) Monographs in Chinese: 6) Huangxian Ju,《Electroanalytical Chemistry and Biosensing Technologies》, Science Press, Beijing, April, 2006 (Chinese) 鞠熀先著，《电分析化学与生物传感技术》，科学出版社，2006.4, 2007.2 第二次印刷 7) Huangxian Ju, Zongying Qiu, Shijia Ding,《Bioanalytical Chemistry》, Science Press, Beijing, 2007.3 (Chinese) 鞠熀先，邱宗荫，丁世家等著，《生物分析化学》，科学出版社，2007.3 8) 《Electrochemical Sensors, Biosensors and their Biomedical Applications》published in Chinese Version, Chemical Industry Press, Beijing, July 2009, 张学记, 鞠熀先, 约瑟夫.王主编，张书圣，李雪梅等译，《电化学与生物传感器--原理、设计及其在生物医学中的应用》, 化学工业出版社，2009.7 9) 《NanoBiosensing — Principles, Development and Application》published in Chinese Version, Science Press, Beijing, June, 2012, 鞠熀先, 张学记, 约瑟夫.王著，雷建平，吴洁，鞠熀先等译，《纳米生物传感--原理、发展及应用》, 科学出版社，2012.8 10) Qixun Dai, Yutao Zhao, Huangxian Ju, Zhenguo Sun, Guanxin Yao,《Scientific and Technological Creativity and Article Writing》, Mechanoindustry Press, Beijing, August, 2004 (Chinese) 戴起勋，赵玉涛编著，鞠熀先，孙振国，姚冠新主审，《科技创新与论文写作》，机械工业出版社，2004.8 11) Xilan Cai, Guoping Wu, Huangxian Ju, 《Experiments for Analysis of Poison and Mico-Evidence》, Nanjing University Press, Nanjing, September, 2009 (Chinese) 蔡锡兰, 吴国萍编著, 鞠熀先审校，《毒物及微量物证分析实验》，南京大学出版社，2009.9

12) Huangxian Ju, Haifeng Dong, Xueji Zhang,《Nucleic Acid Detection: Methods for analysis of DNA and microRNA》, Intellectual Property Press, Beijing, 2015 (Chinese) 鞠熀先，董海峰，张学记著，《核酸检测: DNA与microRNA分析方法》，知识产权出版社，2015

Chapters in Chinese Monographs: 1) Huangxian Ju, Dan Du, Chapter 6 Electrochemical Study of Tumor Cells, In: 《Single Cell Analysis》, Jieke Cheng (Ed), Science Press, Beijing, 2005, p110-p151 (Chinese) 鞠熀先，杜丹，第6章肿瘤细胞的电化学与免疫分析，《单细胞分析》，程介克等著，科学出版社, 2005, p110-p151 2) Huangxian Ju, Chapter 7.2 Electroanalytical Chemistry and Biosensing, In:《Advances in Chemistry Science》, Lihou Zhang (Ed.), Chemical Industry Press, Beijing, 2005, p317-p326 and p363-p364 (Chinese) 鞠熀先，第7.2节电分析化学与生物传感技术，《化学科学进展》，张礼和主编，化学工业出版社，2005, p317-p326 and p363-p364 3) Huangxian Ju, Jin Chen, Chapter 15 Immunosening, In: 《Life Analytical Chemistry》, Erkang Wang, Yi Chen (Eds), Science Press, Beijing, 2006, p350-p364 (Chinese) 鞠熀先，陈进，第15章免疫传感，《生命分析化学》，汪尔康，陈义主编，科学出版社, 2006, p350-p364 4) Huangxian Ju, Analytical methods in glycobiology and protein glycosylation study, In:《100000 Scientific Problems: Chemistry》, Hongyuan Chen (Eds), Science Press, Beijing, 2009, p441-p444 (Chinese) 鞠熀先，糖生物学与蛋白质糖基化研究中的分析方法，《10000个科学难题∙化学卷》，陈洪渊等主编，科学出版社, 2009, p441-p444 5) Huangxian Ju, Chaoyong Yang, Danke Xu, Junjie Zhu, Zhengping Li, Shusheng Zhang, et al., Chapter 10 Analytical chemistry for life science, In: 《Frontiers and Progress in Analytical Chemistry》, Hongyuan Chen, Qiankun Zhuang, Huwei Liu (Eds), Science Press, Beijing, 2012, p350-p400 (Chinese) 鞠熀先，杨朝勇，许丹科，朱俊杰，李正平，张书圣等，第10章生命分析化学，《分析化学学科前沿与展望》，庄乾坤，刘虎威，陈洪渊主编，科学出版社, 2012, p350-p400 6) Huangxian Ju, Lin Ding, Chapter 3 Analysis of the interaction between small organic molecules and biomacromolecules, In:《Frontiers and Progress in Chemical Biology》, Hualiang Jiang, Yongjun Chen, Peng Chen, Lihe Zhang (Eds), Science Press, Beijing, 2013, p76-p119 (Chinese) 鞠熀先，丁霖，第3 章有机小分子-生物大分子相互作用分析检测，《化学生物学前沿与展望》，蒋华良，陈拥军，陈鹏，张礼和主编，科学出版社, 2013, p76-p119 7) Huangxian Ju, Xiaohong Fang, Lin Ding, Xin Zhou, Mailing Liu， Chapter 2 Analytical methods in the study of chemical biology, In:《Developemet Strategy of China Disciplines  Chemical Biology》, Lihe Zhang et al (Eds), Science Press, Beijing, 2014 (Chinese) 鞠熀先，方晓红，丁霖，周欣，刘买利，第2章化学生物学研究中的分析检测方法，《中国学科发展战略化学生物学》，p44-p75，中国科学院编，科学出版社, 2015 8) Huangxian Ju, 1.2 生命分析化学发展展望，中国科学院《2017科学发展报告》，第一章：科学展望，p15-p33，2017 10) Huangxian Ju, 电化学分析仪器的发展回顾，中国仪器仪表学会分析仪器分会，《风雨四十年》， p203-p207，2019 11) Huangxian Ju, Chaoyong Yang, Guodong Ke, Chapter 10 Life analytical chemistry in clinic diagnosis , In:《Developemet Strategy of China Disciplines  Life Analytical Chemistry》鞠熀先，杨朝勇，柯国梁，第10章临床分子诊断中的生命分析化学，《生命分析化学学科发展战略研究》，科学出版社, p280-p331, 2019 Chapters in English Monographs: 12) Huangxian Ju, Hongtao Zhao，Elecirochemical biosensors for DNA analysis, In:《Encyclopedia of Bioscience：Biosensors and their applications》，Ed. by Frontiers in Bioscience, 2005, Vol. 10, 37-46, 13) Huangxian Ju, Zong Dai, Jin Chen ， Amperometric biosensors based on weak interactions and recognition between biomolecule，In:《Encyclopedia of SENSORS》, Craig A. Grimes (Ed), American Scientific Publishers, 2006, Vol 1, 119-144

14) Huangxian Ju, Zhihui Dai, Direct electron transfer and biosensing application of proteins immobilized on NaY zeolite and mesoporous molecular sieves matrices, In:《Trends in Electrochemistry Research》, Magdalena Nunez (Ed), Nova Science Publishers, Inc., 2007, 267-283 15) Huangxian Ju, Shuo Wu, Electrochemical Sensors and Biosensors Based on Nanoporous Silica, In: 《Handbook of Electrochemical Nanotechnology》, Yuehe Lin, H. S. Nalwa (Eds), American Scientific Publishers, 2009, Vol 2, 189-208 16) Jie Wu, Huangxian Ju*, 3.07 Clinical Immunoassays and Immunosensing In:《Comprehensive Sampling and Sample Preparation 》 , Volume 2, Janusz Pawliszyn (Ed), Elsevier INC., 2012, 143-167 doi:10.1016/B978-0-12-381373-2.10071-7 17) Jianping Lei, Huangxian Ju*, Porphyrin-based nanocomposites in biosensing In: 《 Handbook of Porphyrin Science》, Vol. 18, Karl M. Kadish, Kevin M. Smith, Roger Guilard (Eds), World Scientific Publishing Co., June 2012, Chapter 82, 170-212 18) Jianping Lei, Huangxian Ju*, Chapter 2, Signal amplification using nanomaterials for biosensing, In: 《Applications of Nanomaterials in Sensors and Diagnostics》, Adisorn Tuantranont (Ed), Springer Series on Chemical Snsors and Biosensors, 2013, 14, p17-p42, published online: 15 Feb, 2013, doi:10.1007/5346_2012_46 19) Huangxian Ju, Chapter 13, Biosensors based on electrochemiluminescence, In: 《Electrochemical biosensors》, Serge Cosnier (Ed), Pan Stanford Publishing, p337-p370, 2014.8.31 20) Huangxian Ju, Chapter 5, DNA assembly for electrochemical biosensing, In: 《Bioelectrochemistry: Design and application of Biomaterials》, Serge Cosnier (Ed), De Gruyter Publishing, p77-p100, 2019

Editorial, perface or book reviews: 1) Hongyuan Chen and Huangxian Ju, Preface for Publication of the Special Issue of I3S 2004, Sensors 5(4), 160, 2005, doi:10.3390/s5040160 2) Hongyuan Chen and Huangxian Ju, Preface for Nanobiosensing, Sci. China Chem. 54(8), 1155-1156 (2011), DOI: 10.1007/s11426-011-4365-0 3) Huangxian Ju*, Nuclear-uptake nanodrug delivery system for drug-resistant cancer therapy, Sci. China Chem. 58(3), 438 (2015), DOI: 10.1007/s11426-015-5349-2 4) Huangxian Ju, Weihong Tan, Lehui Lu, New researches of State Key Laboratories in Analytical Chemistry, Sci. China Chem. 59(7), 781 (2016), DOI: 10.1007/s11426-016-0256-7 5) Ying Liu, Huangxian Ju*, Ivan Pelant and Jan Valenta: Luminescence spectroscopy of semiconductors, Anal. Bioanal. Chem. 409(6), 1473-1474 (2017), DOI: 10.1007/s00216-016-0106-8 6) Huangxian Ju*, Special Topic: Nanobiosensing, J Anal. Testing DOI: 10.1007/s41664-017-0020-x

Citation: Up to March 30, 2020, 610 papers have been cited by SCI journals for 31186 times, including 29972 times by other authors, the average citation is 47.05, and the h-index is 92 (Google search: 35820 citation with h-index of 101 and i10 of 485). Publications: Annual number of papers published in different journals in English or Chinese Before 95- 99- 2005 2008 In Published Language 1994 98 03 2004 -06 2007 -09 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 review papers In English 7 23 51 31 47 35 43 29 33 36 38 37 42 36 24 43 42 30 9 627 (+9 In Chinese 20 12 11 8 6 2 4 2 1 2 3 1 1 1 1 75 In SCI Journals 6 29 56 34 47 36 44 30 34 36 39 37 43 36 24 43 43 30 9 647 (+9 Total 27 35 62 39 53 37 47 31 34 38 41 38 43 36 25 43 43 30 9 702 (+9 35.0 3 4 14 8 17 19 29 22 25 24 28 28 33 27 20 38 36 27 8 401 (+8 AC+ JACS + 9+1 6+2 2+1 8+2 5+2 4+2 86+21+3 Ang C+NC 1 2+1 1+1 1+1 6 8+2 9 3 6+1 9+2 +1+ 6+5 +1+ +2 1+1+1 +AM+CS 1 2 +1 +2 +2 +2 +14+AF5

List of Publications: Before Dec.1995: 1. Chen Hongyuan*, Ju Huangxian, Xun Yigang, Methylene blue/perfluorosulfonated ionomer modified microcylinder carbon fiber electrode and its application for the determination of hemoglobin, Anal. Chem. 66(24), 4538-4542(1994) 2. Ju Huangxian*, Zhou Jun, Cai Chenxin, Chen Hongyuan, The electrochemical behavior of methylene blue at a microcylinder carbon fiber electrode, Electroanalysis 7(12), 1165-1170(1995) 3. Zhou Jun, Wang Jingsong, Tai Zihou*, Ju Huangxian, Determination of kinetic parameters of 1,1-diacyl-ferrocene at a gold microdisk electrode, J. Electroanal. Chem. 381, 231-234(1995) 4. Cai Chenxin, Ju Huangxian*, Chen Hongyuan, Determination of lactate dehydrogenase by the electrochemical oxidation of NADH at a modified microband gold electrode, Anal. Lett. 28(5), 809-820(1995) 5. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, The effects of temperature and electrolyte on the redox potential of cytochrome C at a chemically modified microband gold electrode, Electrochim. Acta 40, 1109-1112(1995) 6. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, Catalytic oxidation of reduced nicotinamide adenine dinucleotide at a microband gold electrode modified with nickel hexacyanoferrate, Anal. Chim. Acta 310, 145-151(1995) 7. Cai Chenxin*, Ju Huangxian, Chen Hongyuan, Cobalt hexacyanoferrate modified microband gold electrode and its electrocatalytic activity for oxidation of NADH, J. Electroanal. Chem. 397, 185-190(1995) 8. Ju Huangxian*, Xun Yigang, Chen Hongyuan, Heterogeneous catalytic reaction at a methylene blue/Nafion® modified carbon fiber microcylinder electrode, J. Electroanal. Chem. 380, 283-285(1995) 9. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, Electrochemical characteristics and applications of thiophenol self- assembling monolayer modified gold electrode, Chin. Sci. Bull. 40(22), 1888-1893 (1995) 10. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, Electrochemical properties of polypyrrole-coated microelectrode array and the fabrication of polypyrrole-based microelectronic devices, Chem. Res. Chinese Univ, 11(2), 163- 169(1995) 11. Ju Huangxian, Chen Hongyuan*, Gao Hong, Investigation of microelectrodes IX: Study of the edge effects at a microdisk electrode, J. Electroanal. Chem. 361, 251-256(1993) 12. Ju Huangxian, Chen Hongyuan*, Gao Hong, Investigation on microelectrodes Part XVI. Study of the shielding effect at a microband-array electrode, J. Electroanal. Chem. 341, 35-46(1992) 13. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, Electrocatalysis of nickel hexacyanoferrate modified microband gold electrode for oxidation of reduced nicotinamide adenine dinucleotide, Chinese Chem. Lett. 6(6), 501- 504(1995) 14. Ju Huangxian*, Xun Yigang, Chen Hongyuan, Investigation on carbon fiber microelectrodes XIX. Heterogeneous catalytic reaction at methylene blue/Nafion modified microcylinder carbon fiber electrode and the determination of hemoglobin, Chinese Chem. Lett. 5(3), 249-252(1994) 15. Chen Hongyuan*, Cai Chenxin, Ju Huangxian, 4,6-Dimethyl-2-mercaptopyrimidine as new promoter for the voltammetric response of horse heart cytochrome C at a microband gold electrode, Chinese Chem. Lett. 5(11), 975-978(1994) 16. Ju Huangxian, Chen Hongyuan*, Gao Hong, Investigation on microelectrodes XⅡThe determination of the inverse current in the processes of steady-state or quasi-steady state, Chinese Chem. Lett. 3(6), 453-456(1992) 17. Chen Hong-yuan*, Fang Hui-qun, Ju Huang-xian, Li Hui-bin, Study on the determination of trace rhenium (VII) by the adsorption differential pulse polarography, Acta Chim. Sinica Eng. Ed. No.5, 412-421(1989) 18. Ju Huangxian*, Dong Ling, Chen Hongyuan, The study on the electrochemical behaviour of nile blue A modified carbon fiber microcylinder electrode, Chem. J. Chinese Universities 16(8),1200-1203(1995) 19. Ju Huangxian*, Ma Wei, Cai Chenxin, Chen Hongyuan, The electrochemistry of nicotinamide-adenine dinucleotide at a β-naphthochinonsulfonicum modified gold band electrode, Chem. J. Chinese Universities 16(11), 1680-1684(1995) 20. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, Fabrication and electrochemical characterization of inter-digitated array microband electrode, Chem. J. Chinese Universities 16(6), 854-858(1995) 21. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, Electrochemical behavior, application and immobilization of glucose oxidase at nanometer-sized ultramicroband gold electrode, Acta Chim. Sinica 53(3), 281-285(1995) 22. Cai Chenxin, Chen Hongyuan*, Ju Huangxian, Direct electrochemistry of cytochrome c at a microband gold electrode modified with 4,6-dimethy1-2-mercaptopyrimidine, Acta Chim. Sinica 53(3), 286-290(1995) 23. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, Electrochemical characteristics and applications of thiophenol self- assembling monolayer modified gold electrodes, Chin. Sci. Bull. 40(12), 1093-1096(1995)

24. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, Studies on the electrode process thermodynamics of cytochrome C at a microband gold electrode modified with 4,6-dimethy1-2-mercaptopyrimidine, Chem. J. Chinese Universities 16(1), 31-34(1995) 25. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, Electrocatalysis of poly-thionine modified microband gold electrode for oxidation of reduced nicotinamide adenine dinucleotide, Chem. J. Chinese Universities 16(3), 368- 372(1995) 26. Cai Chenxin, Ju Huangxian, Chen Hongyuan*, Fabrication and characterization of nanometer-sized gold electrode and its applications to heterogeneous catalytic reactoins, Fenxi Huaxue(Anal. Chem.) 23(1), 20-24(1995) 27. Ju Huangxian, Chen Hongyuan*, Investigation on carbon fiber microelectrodes XX. The electrochemical behaviours of toluidine blue at a carbon fiber microdisk electrode, Acta Chim. Sinica 52(11), 1118-1125(1994) 28. Ju Huangxian*, Xun Yigang, Chen Hongyuan, Investigation on carbon fiber microelectrodes (XVIII) The determination of hemoglobin at a methylene blue/Nafion modified carbon fiber microcylinder electrode, Chem. J. Chinese Universities 15(6), 827-831(1994) 29. Ju Huangxian*, Xun Yigang, Chen Hongyuan, Study on determination of hemoglobin with a carbon fiber microelectrode, Guowai Yixue, Clinic Biochemistry and Examination 15(2), 162-163(1994) 30. Ju Huangxian*, Chen Hongyuan, Yan Guifeng, Zhang Tingqing, Electroanalytical chemistry in clinical determination, Guowai Yixue, Clinic Biochemistry and Examination 15(2), 164-165(1994) 31. Ju Huangxian*, Chen Hongyuan, Kao Hong, Characteristics and applications of microelectrode array, Fenxi Huaxue (Anal. Chem.) 20(1), 107-113(1992) 32. Yan Guifeng*, Zhang Tingqing, Ju Huangxian, Chen Hongyuan, The application of electrochemistry biosensors in clinic determination, Chinese J. Clin. Lab. Sci. 10(2), 103-104(1992) 33. Ju Huangxian, Chen Hongyuan*, Gao Hong, Investigation on microelectrodes (X)-The steady-state differential voltammetry on microdisc electrode, Chem. J. Chinese Universities 13(5), 586-589(1992) 34. Ju Huangxian, Chen Hongyuan*, Gao Hong, Investigation on microelectrodes VII. Studay of mass transfer rate on microdisk electrode, Fenxi Huaxue(Anal. Chem.) 20(9), 997-1001(1992) 35. Ju Huangxian, Chen Hongyuan*, Gao Hong, Investigation on microelectrodes XV. Diffusion on microband and microband-array electrodes, Acta Chim. Sinica 50(9), 895-900(1992) 36. Ju Huangxian, Chen Hongyuan*, Gao Hong, Investigation on microelectrode Ⅷ. The retention effect of voltammogram at a microdisk electrode, Acta Chim. Sinica 50, 1010-1016(1992) 37. Ju Huangxian, Chen Hongyuan*, Gao Hong, investigation on carbon fiber microelectrode (XI) The determination of the thermodynamics and kinetics parameters by the temperature effect, Chem. J. Chinese Universities 13(11), 1374-1377(1992) 38. Ju Huangxian, Chen Hongyuan*, Investigation on microelectrodes III. The Study of the electrodeposition processes of Hg2+ on carbon fiber microelectrode, Acta Chim. Sinica 49, 694-699(1991) 39. Chen Hongyuan*, Ju Huangxian, Investigation on carbon fiber microelectrodes (V)--The kinetics of ferrocene and its derivatives on carbon fiber ultramicroelectrodes, Chem. J. Chinese Universities 12(11), 1459-1461(1991) 40. Chen Hongyuan*, Ju Huangxian, Investigation on microelectrodes VI. Studies of anodic stripping voltammetry at carbon fiber microelectrode, Bull. Analysis & Testing 10(2), 34-38(1991) 41. Ju Huangxian, Chen Hongyuan*, Progress in the study of carbon fiber microelectrode, Chemical Sensors 10(1), 1-6(1990) 42. Ju Huangxian, Chen Hongyuan*, Investigation on carbon fiber microelectrodes IV. Determination of trace Cu2+, Pb2+, In3+, Cu2+ and Zn2+ by ASV, Fenxi Huaxue(Anal. Chem.) 18(12), 1175-1176(1990) 43. Ju Huangxian, Chen Hongyuan*, Development of adsorption voltammetry, Trace Anal. (1-2),15-27(1990) + 44. Chen Hongyuan, Ju Huangxian*, Han Jilin, Effect of NH4 (NH3 ) on the electrode process of the system "Co(II)- DMG", Electroanal. Chem. 2(1), 34-40(1988) 45. Chen Hongyuan*, Ju Huangxian, Wu Chiping, The study of carbon fiber microelectrodes I. Fabrication, pretreatment and voltammetric characteristics, Chemical Sensors 8(4), 28-33 (1988) 46. Ju Huangxian, Chen Hongyuan*, Wu Chiping, The study of carbon fiber microelectrodes II. Surface characteristics and the modification with Nafion, Chemical Sensors 8(4), 34-39 (1988) 1996 - 1998: 47. Huangxian Ju*, Hongbin Sun, Hongyuan Chen, Properties of poly-β-aminoanthraquinone modified carbon fiber electrode as a basis for hemoglobin biosensors, Anal. Chim. Acta 327, 125-132(1996) 48. Huangxian Ju*, Ling Dong, Hongyuan Chen, Amperometric determination of lactate dehydrogenase based on a carbon fiber microcylinder electrode modified covalently with tolduidine blue O by acylation, Talanta 43, 1177- 1183(1996)

49. Huangxian Ju*, Ling Dong, Hongyuan Chen, Electrochemical behavior of toluidine blue O covalently modified microcylinder carbon fiber electrode and amperometric determination of hemoglobin in whole blood, Anal. Lett. 29(4), 587-599(1996) 50. Dongmei Zhou, Huangxian Ju, Hongyuan Chen*, Catalytic oxidation of dopamine at a microdisk platinum electrode modified by electrodeposition of nickle hexacyanoferrate and Nafion®, J. Electroanal. Chem. 408, 219- 223(1996) 51. Dong-mei Zhou, Hui-qun Fang, Hong-yuan Chen*, Huang-Xian Ju, Yun Wang, The electrochemical polymerization of methylene green and its electrocatalysis for the oxidation of NADH, Anal. Chim. Acta 329, 41-48(1996) 52. Hongyuan Chen*, Chenxin Cai, Huangxian Ju, Biomolecular sensor based on a polypyrrole-coated microelectrode array, Chin. Sci. Bull. 41(17), 1441-1445(1996) 53. Huangxian Ju, Donal Leech*, Electrochemistry of poly(vinylferrocene) formed by direct electrochemical reduction at a glassy carbon electrode, J. Chem. Soc., Faraday Trans. 93(7), 1371-1375(1997). 54. Huangxian Ju, Donal Leech*, [Os(bpy)2(PVI)10Cl]Cl polymer-modified carbon fiber electrodes for the electrocatalytic oxidation of NADH, Anal. Chim. Acta 345, 51-58(1997). 55. Dongmei Zhou, Huangxian Ju, Hongyuan Chen*, A miniaturized glucose biosensor based on the coimmobilization of glucose oxidase and ferrocene perchloride in Nafion at a microdisk platinum electrode, Sens. Actuat. B: Chem. 40, 89-94(1997). 56. Yuming Zhou*, Yuhua Ge, Shaohua Gou, Huangxian Ju, Juzheng Liu, Synthesis of a novel macrocyclic dinuclear iron (III) complex and its electrochemical behavior on an utramicrodisk platinum electrode, Trans. Metal Chem. 22, 347-349(1997) 57. Huangxian Ju, Donal Leech*, Host-guest interaction at a self-assembled monolayer/solution interface: An electrochemical analysis of the inclusion of 11-(ferrocenylcarbonyloxy)undecanethiol by cyclodextrins, Langmuir 14, 300-306(1998) 58. Huangxian Ju*, Dongmei Zhou, Yi Xiao, Hongyuan Chen, Amperometric biosensor for glucose based on a nanometer-sized microband gold electrode coimmobilized with glucose oxidase and poly-(o-phenylenediamide), Electroanalysis 10(8), 541-545(1998) 59. Jingan Ni, Huangxian Ju, Hongyuan Chen*, Donal Leech, [Os(bpy)2(PVI)10Cl]Cl polymer and Nafion dual-film modified graphite electrode for the amperometric determination of trace amounts of norepinephrine, Analyst 123(12), 2895-2898(1998). 60. Ji Bin, Tai Zihou*, Ju Huangxian, Li Chun, 微铂电极上1-酰基二茂铁动力学参数的测定, 无机化学学报 Determination of kinetic parameters of 1-acylferrocene at a platimum microelectrode, Chinese J. Inorg. Chem. 12(3), 260-266 (1996). 61. Hongyuan Chen*, Chenxin Cai, Huangxian Ju, 阵列微电极上分子器件的研究，科学通报 NADH sensors based on a polypyrrole-coated microelectrode array, Chin. Sci. Bull. 41(8), 711-714(1996)

62. Yuming Zhou*, Yuhua Ge, Shaohua Gou, Huangxian Ju, Juzheng Liu, Ni2L配合物的热稳定性和电化学研究，物理化学学报 The thermal stability and electrochemical behaviors of a novel macroyclic dinuclear nickel(IIIP )B complex, Chinese J. Phys. Chem. 13, 598-602 (1997) 1999-2002: 63. Jinan Ni, Huangxian Ju, Hongyuan Chen*, Donal Leech, Amperometric determination of epinephrine with an osmium complex and Nafion double-layer membrane modified electrode, Anal. Chim. Acta 378, 151-157(1999) 64. Huangxian Ju, Guifeng Yan, Feng Chen, Hongyuan Chen*, Enzyme-linked immunoassay of -1-fetoprotein in serum by differential pulse voltammetry, Electroanalysis 11(2), 124-128(1999) 65. Guifeng Yan, Huangxian Ju*, Zhichao Liang, Tingqing Zhang, Technical and clinical comparison of two fully automated methods for the immunoassay of CA 125 in serum, J. Immunol. Methods 225(1-2), 1-8(1999) 66. Huangxian Ju*, Donal Leech, Effect of electrolytes on the electrochemical behaviour of 11- (ferrocenylcarbonyloxy)undecanethiol SAMs on gold disk electrodes, Phys. Chem. Chem. Phys. 1(7), 1549- 1554(1999) 67. Yi Xiao, Huangxian Ju, Hongyuan Chen*, Hydrogen peroxide sensor based on horseradish peroxidase-labeled Au colloids immobilized on gold electrode surface by cysteamine monolayer, Anal. Chim. Acta 391(1), 73-82(1999) 68. Yi Xiao, Huangxian Ju, Hongyuan Chen*, A reagentless hydrogen peroxide sensor based on incorporation of horseradish peroxidase in poly(thionine) film on a monolayer modified electrode, Anal. Chim. Acta 391(3), 299- 306(1999). 69. Raluca Voicu, Tom Ellis*, Huangxian Ju, Donal Leech, Adsorption and desorption of electroactive self-assembled thiolate monolayers on gold, Langmuir 15, 8170-8177(1999)

70. Huangxian Ju*, Jinan Ni, Yi Gong, Hongyuan Chen, Donal Leech, Electrocatalytical oxidation and determination of dopamine at redox polymer/Nafion modified electrodes, Anal. Lett. 32(15), 2951-2964(1999) 71. Yi Xiao, Huangxian Ju, Hongyuan Chen*, Direct electrochemistry of horseradish peroxidase immobilized on a colloid /cysteamine-modified gold electrode, Anal. Biochem. 278, 22-28(2000) 72. Yong Yao, Huangxian Ju, Yibin Wu, Sijun Yang, Wenxia Tang*, Electrochemical study on the alkaline isomerization of cytochrome c and ligand-binding cytochrome c in the presence of pyridine and 2-methyl-pyridine, Chinese Inorg. Chem. Acta 16(2), 346-352(2000) (in English) 73. Huangxian Ju, Donal Leech*, Electrochemical study of a metallothionein modified gold disk electrode and its action on Hg2+ cations, J. Electroanal. Chem. 484, 150-156(2000) 74. Ming Qian, Shaohua Gou*, Huangxian Ju, W. Huang, Chunying Duan, Xiaozeng You, A mononuclear manganese 2 (III) complex of an asymmetric macrocyclic ligand with a ring contraction [MnHLB (ClOB 4B )]ClOB 4B B 2.5H2B O,B Trans. Metal Chem. 25, 584-588(2000) 75. Huangxian Ju*, Yi Gong, Hongqin Zhu, Electrolyte effects on electrochemical properties of osmium complex polymer modified electrodes, Anal. Sci. 17, 59-63(2001) 76. Rongxin Yuan, Rengen Xiong*, Zhenfeng Chen, Pei Zhang, Huangxian Ju, Zong Dai, Zijian Guo, Hoongkun Fun, Xiaozeng You* , Crystal structure of zinc(II) 2-sulfanilamidopyrimidine: a widely used topical burn drug, J. Chem. Soc., Dalton Trans. (Communication) 774-776(2001) 77. Huangxian Ju*, Chunze Shen, Electrocatalytic reduction and determination of dissolved oxygen at a poly(nile blue) modified electrode, Electroanalysis 13(8-9), 789-793(2001) 78. Ming Qian, Shaohua Gou*, Zhi Yu, Huangxian Ju, Yan Xu, Chunying Duan, Xiaozeng You, Synthesis, crystal structure and properties of a macrocyclic dinuclear manganese(II) complex with functional o-methylene-phenolic pendant arms, Inorg. Chim. Acta 317, 157-162(2001) 79. Zong Dai, Huangxian Ju*, Effect of chain length on the surface properties of ω-carboxy alkanethiol self-assembled monolayers, Phys. Chem. Chem. Phys. 3(17), 3769-3773(2001) 80. Wang Hui-Sheng, Huang-Xian Ju, Hong-Yuan Chen*, Votammetric behavior and detection of DNA at electrochemically pretreated glassy carbon electrode, Electroanalysis 13(13), 1105-1109(2001) 81. Jinan Ni, Huangxian Ju, Hongyuan Chen*, Donal Leech, 儿茶酚胺类神经递质在锇配位聚合物和 Nafion 双层膜修饰碳基电极上的电催化氧化及其痕量测定，高等学校化学学报 Electrocatalytic oxidation and trace determination of catecholamine neurotransmitters at osmium complex polymer and Nafion dual-layer membrane carbon-base electrode, Chem. J. of Chinese Universities 20(2), 224-226 (1999). (a SCI journal ) 82. Guifeng Yan, Huangxian Ju*, New techniques for fast clinic examinations based on amperometric immunosensors, 安培免疫传感器用于快速临床检测的新方法，国外医学临床生物化学与检验学分册 Guowai Yixue, Clinic Biochemistry and Examination 20(4), 172-174 (1999) 83. Gong Yi, Lei Ye, Ju Huangxian*, Chen Hongyuan, Electrocatalysis of osmium poly-vinylindole complex modified glassy carbon electrodes to epinephrine oxidation, 锇-聚乙烯吲哚配合物修饰玻碳电极对肾上腺素的电催化氧化, 高等学校化学学报 Chem. J. of Chinese Universities 21(2), 202-205 (2000) 84. Huangxian Ju*, Yi Xiao, Xiaojun Lu, Hongyuan Chen, Electrooxidative coupling of a toluidine blue O terminated self-assembled monolayer studied by electrochemistry and surface enhanced Raman spectroscopy, J. Electroanal. Chem. 518, 123-130 (2002) 85. Huangxian Ju*, Songqin Liu, Bixia Ge, Fred Lisdat, Frieder W. Scheller, Electrochemistry of cytochrome c immobilized on colloidal gold modified carbon paste electrodes and its electrocatalytic activity, Electroanalysis 14(2), 141-147 (2002) 86. Huangxian Ju*, Zong Dai, Donal Leech, Electrochemical determination of electroinactive guests of -cyclodextrin at a self-assembled monolayer interface, Science in China B. 45(1), 46-53 (2002) 87. Huangxian Ju*, Zong Dai, Donal Leech, Electrochemical determination of electroinactive guests of -cyclodextrin at a self-assembled monolayer interface, 自组装单层界面-环糊精非电活性客体的电化学测定, 中国科学B 辑 Science in China B (Chinese) 32(1), 40-45 (2002) 88. Huisheng Wang, Huangxian Ju, Hongyuan Chen*, Simultaneous determination of guanine and adenine in DNA using an electrochemically pretreated glassy carbon electrode, Anal. Chim. Acta 461, 243-250 (2002) 89. Liu Songqin, Huangxian Ju*, Renewable reagentless hydrogen peroxide sensor based on direct electron transfer of horseradish peroxidase immobilized on colloidal gold-modified electrode, Anal. Biochem. 307(1), 110-116 (2002) www.academicpress.com/ab 90 Jiuhong Yu, Huangxian Ju*, Preparation of porous titania sol-gel matrix for immobilization of horseradish peroxidase by a vapor deposition method, Anal. Chem. 74(14), 3579-3583 (2002)

91. Jiayin Gu, Xiaojun Lu, Huangxian Ju*, DNA sensor for recognition of native yeast DNA sequence with methylene blue as an electrochemical hybridization indicator, Electroanalysis 14(13), 949-954 (2002) 92. Mingliang Wang*, Junxiang Zhang, Juzheng Liu, Chunxiang Xu, Huang-Xian Ju, Intramolecular energy and charge transfer in 5-(9-anthryl)-3-(4-nitrophenyl)-1-phenyl-2-pyrazoline, J. of Luminescence, 99(1), 79-83 (2002) 93. Xue X, Wang XS, Xiong RG*, You XZ, Abrahams BF*, Che CM, Ju HX, A cluster rearrangement of an open cubane (Cu4B BrB 4B )B to a prismane (Cu6B BrB 6B )B in a copper(I)-olefin network, Angew. Chem. Int. Ed. 41 (16), 2944- 2946 (2002) 94. Sichun Zhang, Guojun Zhou, Huangxian Ju*, Flow-injection chemiluminescence sensor for the determination of gallic acid based by immobilizing luminol and periodate on anion exchange resin, J. of Chinese Chem., 20, 1049- 1054 (2002) 95. Ye Bao-Fen , Zhu Yong-Lin, Ju Huang-Xian* DNA与苯胺红T的相互作用与荧光定量检测，高等学校化学学报 Interaction between safranine T and yeast DNA and fluorescence-quantitative determination of DNA，Chem. J. Chinese Universities 23, 2253-2255 (2002) 96. Huisheng Wang, Huangxian Ju, Hongyuan Chen*, Adsorptive stripping voltammetric detection of sing-stranded DNA at electrochemically modified glassy carbon electrode, Electroanalysis 14(23), 1615-1620 (2002) 2003 97. Songqin Liu, Jiuhong Yu, Huangxian Ju*，Renewable phenol biosensor based on a tyrosinase-colloidal gold modified carbon paste electrode, J. Electroanal. Chem. 540, 61-67 (2003) 98. Sichun Zhang, Huangxian Ju*, -Cyclodextrin sensitized chemiluminescence of hemoglobin-hydrogen peroxide- carbonate and its analytical application, Anal. Chim. Acta 475(1-2), 163-170 (2003) 99 Yafeng Zhuang, Sichun Zhang, Junsheng Yu, Huangxian Ju*, Flow injection determination of papaverine based on its sensitizing effect on the chemiluminescence reaction of permanganate-sulfite, Anal. Bioanal. Chem. 375(2), 281-286 (2003) 100. Lu Xiaojun, Ju Huangxian*,脱氧核糖核酸电化学传感器的原理及其应用，分析化学 Electrochemical deoxyribonucleic acid biosensors and their applications，Chin J. Anal. Chem. 31, 110-115 (2003) 101. Songqin Liu, Dónal Leech, Huangxian Ju*, Application of colloidal gold in protein immobilization, electron transfer and biosensing, Anal. Lett. 36(1), 1-19 (2003) 102. Huangxian Ju*, Yongkang Ye, Jianhua Zhao, Yonglin Zhu, Hybridization biosensor using di(2,2’- bipyridine)osmium (III) as electrochemical indicator for detection of polymerase chain reaction product of hepatitis B virus DNA, Anal. Biochem. 313(2), 255 – 261 (2003) 103. Zhu Guanghua, Ju Huangxian*, Ye Baofen, A sensitive fluorescence quenching method for the determination of iron(Ⅱ) with 1,10-phenanthroline, Chin. J. Chem. 21(3), 301-304 (2003) 104. Baofeng Ye, Huangxian Ju*, Determination of yeast DNA based on its quenching the fluorescence emission of norfloxacin, Anal. Lett. 36(7), 1351-1364 (2003) 105. Guanghua Zhu, Huangxian Ju*, 仪器分析发展史在大学教学中的应用探讨, 大学化学 Application of the history of instrumental analysis in college teaching, University Chemistry 18(4), 30-32 (2003) 106. Sichun Zhang, Guojun Zhou, Huangxian Ju*, Chemiluminescence sensor for the determination of hydroxylamine by electrostatically immobilizing luminol and periodate, Chem. Research in Chinese University 19(2), 155-159 (2003) 107. Jiuhong Yu, Huangxian Ju*, Amperometric biosensor for hydrogen peroxide based on hemoglobin entrapped in titania sol-gel film, Anal. Chim. Acta 486(2), 209-216 (2003) 108. Yongkong Ye, Jianhua Zhao, Feng Yan, Yonglin. Zhu, Huangxian. Ju*,P P Electrochemical behavior and detection of hepatitis B virus DNA PCR production at gold electrode, Biosens. Bioelectron. 18, 1501-1508 (2003) 109. Songqin Liu, Huangxian Ju*, Reagentless glucose biosensor based on direct electron transfer of glucose oxidase immobilized on colloidal gold modified carbon paste electrode, Biosens. Bioelectron. 19, 177-183 (2003) 110. Li YX, Chen ZF*, Xiong RG*, Xue ZL, Ju HX*, You XZ, A mononuclear complex of norfloxacin with silver(I) and its properties, Inorg. Chem. Comm. 6, 819-822 (2003) 111. Cai Xilan, Wu Guoping, Zhang Damin, Ju Huangxian*, 傅里叶变换红外光谱和气相色谱--质谱法快速检测鼠药, 分析化学 Fast detection of raticides by Fourier transform infrared spectrometry and gas chromatography- mass spectrometry, Chin J. Anal. Chem. 31, 836-839 (2003) 112. Xiaoxing Xu, Songqin Liu, Bin Li, Huangxian Ju*, Disposable nitrite sensor based on hemoglobin-colloidal gold nanoparticle modified screen-printed electrode, Anal. Lett. 36(11), 2427-2442 (2003) 113. Yongkang Ye, Huangxian Ju*, DNA electrochemical behaviours, recognition and sensing by combining with PCR technique, Sensors 3, 128-145 (2003)

114. Guanghua Zhu, Yongzhen Hu, Hong Zheng, Huangxian Ju*, L-组氨酸分光光度法测定消毒剂中的邻苯二甲醛，分析科学学报 Spectrophotometric determination of o-phthalaldehyde by using L-histidine，Chin. J. Anal Sci 19(5), 478-479 (2003) 115. Yongkang Ye, Huangxian Ju*, DNA 浓度及序列检测的电化学传感器研究，分析科学学报 DNA electrochemical behaviors, recognition and detection on modified electrodes, Chin. J. Anal Sci 19(5), 494-496 (2003) 116. Zong Dai, Feng Yan, Jin Chen, Huangxian Ju*, Reagentless amperometric immunosensors based on direct electrochemistry of horseradish peroxidase for determination of carcinoma antigen-125, Anal. Chem. 75 (20), 5429-5434 (2003) 117. Songqin Liu, Huangxian Ju*, Electrocatalysis via direct electrochemistry of myoglobin immobilized on colloidal gold nanoparticles, Electroanalysis 15(18), 1488-1493 (2003) 118. Xiaoxing Xu, Songqin Liu, Huangxian Ju*, A novel hydrogen peroxide sensor via the direct electrochemistry of horseradish peroxidase immobilized on colloidal gold modified screen-printed electrode, Sensors 3, 350-360 (2003) 119. Jiuhong Yu, Songqin Liu, Huangxian Ju*, Glucose sensor for flow injection analysis of serum glucose based on immobilization of glucose oxidase in titania sol-gel membrane, Biosens. Bioelectron. 19(4), 401-409 (2003) 120. Jiuhong Yu, Songqin Liu, Huangxian Ju*, Mediator-free phenol sensor based on titania sol-gel encapsulation matrix for immobilization of tyrosinase by a vapor deposition method, Biosens. Bioelectron. 19(5), 509-514 (2003) 121. Dan Du, Feng Yan, Shengli Liu, Huangxian Ju*, Immunological assay for carbohydrate antigen 19-9 using an electrochemical immunosensor and antigen immobilization in titania sol–gel matrix, J. Immunol. Methods 283(1- 2), 67-75 (2003) 122. Wei Wei, Ju Huangxian*, Affinity capillary electrophoresis studies on the influence of alcohols on the interaction of β-cyclodextrin with non-steroidal anti-inflammatory drugs, Chromatographia 58(7/8), 449-453 (2003) 123. Songqin Liu, Huangxian Ju*, Nitrite reduction and detection at a carbon paste electrode containing hemoglobin and colloidal gold, Analyst 128(12), 1420–1424 (2003) 124. Shengli Liu, Jingmin Wang, Huangxian Ju, Guanghua Zhu, Dan Du, Chunfu Zhu, Hao Xu, Hai Huang, 潘生丁抑制平衡型核苷转运蛋白对5氟尿嘧啶在胰腺癌细胞内浓聚的影响, 中国药科大学学报 Effect of inhibiting equilibrative nucleoside transport proteins with dipyridamole on 5-FU Intracellular accumulation in pancreatic cancer cell, J. China Pharmaceutical Univ. 34(6), 544-548 (2003) 2004 125. Daming Zhang, Xuejun Shi, Zengping Yuan, Huangxian Ju*, Component analysis of illicit heroin with GC/MS and its application in source identification, J. Forensic Sci. 49(1), 81-86 (2004) 126. Sichun Zhang, Yafeng Zhuang, Huangxian Ju*, Flow-injection chemiluminescence determination of papaverine using cerium(IV)-sulfite system, Anal. Lett. 37(1) 143-155 (2004) 127. Jianhua Zhao, Feng Yan, Huangxian Ju*, Jinghai Tang, Jianhei Qin, Correlation between serum vascular endothelial growth factor and endostatin levels in patients with breast cancer, Cancer Lett. 204(1), 87-95 (2004) 128. Zhu Guanghua, Zheng Hong, Ju Huangxian*, 荧光偏振免疫分析技术的研究进展，分析化学 Development of fluorescence polarization immunoassay，Chin J. Anal. Chem. 32(1), 102-106 (2004) 129. Yong-Hua Li, Xi-Sen Wang, Hong Zhao, Rong-Xin Yuan*, Jing Zhang, Ren-Gen Xiong*, Xiao-Zeng You, Huang-Xian Ju, and Zi-Ling Xue, Three olefin copper(I) dimeric complexes with 2-, 3-, and 4-pyridylacrylic acid and their electrochemical properties, Inorg. Chem. 43, 712-715 (2004) 130. Zhihui Dai, Songqin Liu, Huangxian Ju*, Hongyuan Chen, Direct electron transfer and enzymatic activity of hemoglobin in a hexagonal mesoporous silica matrix, Biosens. Bioelectron. 19(8), 861-867 (2004) 131. Zhu Guanghua, Ju Huangxian*, Determination of naproxen with solid substrate room temperature phosphorimetry based on an orthogonal array design, Anal. Chim. Acta 506(2), 177-181 (2004) 132. Yafeng Zhuang, Xilan Cai, Junsheng Yu, Huangxian Ju*, Flow injection chemiluminescence analysis for highly sensitive determination of noscapine, JT . Photochem. Photobiol. A: Chem., 162(2-3), 457-462 (2004) 133. Songqin Liu, Zhihui Dai, Hongyuan Chen, Huangxian Ju*, Immobilization of hemoglobin on zironium dioxide nanoparticles for preparation of a novel hydrogen peroxide biosensor, Biosens. Bioelectron. 19(9) 963-969 (2004) 134. Jiehua Lin, Feng Yan, Huangxian Ju*, Noncompetitive enzyme immunoassay for carcinoembryonic antigen by flow injection chemiluminescence, Clin. Chim. Acta 341(1-2), 109-115 (2004) 135. Wei Wei, Xiaodong Yu, Huangxian Ju*, Simultaneous determination of several antalgic drugs based on their interactions with -cyclodextrin by capillary zone electrophoresis, J. Chromatogr. Sci. 42(3), 155-160 (2004)

136. Zhihui Dai, Songqin Liu, Huangxian Ju*, Direct electron transfer of cytochrome c immobilized on a NaY zeolite matrix and its application in biosensing, Electrochim Acta 49(13), 2139-2144 (2004) 137. Yun Shan, Yuming Zhou*, Yong Cao, Qunhua Xu, Huangxian Ju, Zonghan Wu, Preparation and infrared emissivity study of collagen-g-PMMA/In2B OB 3B B nanocomposite, Mater. Lett. 58, 1655–1660 (2004) 138. Xilan Cai, Daming Zhang, Huangxian Ju*, Guoping Wu, Xianping Liu, P PFast detection of fluoroacetamide in body fluid using gas chromatography-mass spectrometry after solid-phase microextraction, J. Chromatogr. B 802(2), 239-245 (2004) 139. Huangxian Ju*, Baofeng Ye, Jiayin Gu, Supermolecular interaction of ferrocenium with yeast DNA and application in electrochemical sensing for hybridization recoginition of yeast DNA, Sensors 4, 57-68 (2004) 140. Zong Dai, Feng Yan, Hua Yu, Xiaoya Hu, Huangxian Ju*, Novel amperometric immunosensor for rapid separation- free immunoassay of carcinoembryonic antigen, J. Immunol. Methods 287(1-2), 13-20(2004) 141. Jianping Lei, Huangxian Ju, Osamu Ikeda*, Supramolecular assembly of porphyrin bound DNA and its catalytic behavior for nitric oxide reduction, Electrochim. Acta 49(15), 2453-2460(2004) 142. Wei Wei, Zhijie Zhang, Huangxian Ju*, Study on interactions of several psychopharmaceutical drugs with - cyclodextrin by affinity capillary electrophoresis and their application in separation, Chromatographia 59, 513- 516(2004) P 143. Jianping Lei B ,PB Huangxian Ju, Osamu Ikeda*, Catalytic oxidation of nitric oxide and nitrite mediated by water- soluble high-valent iron porphyrin at an ITO electrode, J. Electroanal. Chem. 567(2), 331-338(2004) 144. Zhuang Yafeng, Yu Junsheng, Ju Huangxian*, Gao Feng, 仪器分析教学软件的设计与研制大学化学 Dsign and preparation of “instrumental analysis” teaching software, University Chemistry 19(3), 44-48 (2004) 145. Yuming Zhou*, Yun Shan, Yong Cao, Qunhua Xu, Huangxian Ju, Zonghan Wu, 胶原接枝改性用于制备红外低发射率涂层的研究, 高等学校化学学报 Studies on grafting modification of collagen and application to preparation of low IR emissivity coating, Chem. J. Chin. Univ. 25(5), 966-970 (2004) 146. Jiehua Lin, Feng Yan, Huangxian Ju*, Noncompetitive enzyme immunoassay for α-fetoprotein using flow injection chemiluminescence, Applied Biochem. Biotech. 117(2), 93-102 (2004) 147. Hua Yu, Feng Yan, Zong Dai, Huangxian Ju*, A disposable amperometric immunosensor for -1-fetoprotein based on enzyme-labeled antibody/chitosan-membrane-modified screen-printed carbon electrode, Anal. Biochem. 331(1), 98-105 (2004) 148. Zhihui Dai, Xiaoxing Xu, Huangxian Ju*, Direct electrochemistry and electrocatalysis of myoglobin immobilized on a hexagonal mesoporous silica matrix, Anal. Biochem. 332, 23-31(2004) 149. Xiaoxing Xu, Songqin Liu, Huangxian Ju*, Disposable biosensor based on a hemoglobin colloidal gold-modified screen-printed electrode for determination of hydrogen peroxide, IEEE Sensors Journal 4(4), 390- 394(2004) 150. Jiuhong Yu, Huangxian Ju*，Pure organic phase phenol biosensor based on tyrosinase entrapped in a vapor deposited titania Sol-Gel membrane, Electroanalysis 16(16), 1305-1310 (2004) 2+P 151. Yafeng Zhuang, Huangxian Ju*, Study on electrochemiluminesce of Ru(bpy3B )B P immobilized in a titania sol-gel membrane, Electroanalysis 16(17), 1401-1405 (2004) 152. Guanghua Zhu, Huangxian Ju*, Hong Zheng, Fluorescence spectroscopic determination of dipyridamole binding on pancreas-1 tumor cell membrane, Clin. Chim. Acta 348(1-2), 101-106(2004) 153. Vivek Babu Kandimalla, Huangxian Ju*, New horizons with a multi dimensional tool for applications in analytical chemistry – aptamer, Anal. Lett. 37(11), 2215–2233(2004) 154. Yong Cao, Yuming Zhou*, Yun Shan, Huangxian Ju*, Xuejia Xue, Zonghan Wu, (Ti,Sn)O2 solid solution self- aligned into “sandwich” array on grafted modification collagen matrix, Adv. Mater. 16(14), 1189-1192 (2004) 155. Jiehua Lin, Feng Yan, Xiaoya Hu, Huangxian Ju*, Chemiluminescent immunosensor for CA 19-9 based on antigen immobilization on a cross-linked chitosan membrane, J. Immunol. Methods 291(1-2), 165-174 (2004) 156. Hongtao Zhao, Huangxian Ju*, Biosensor for hepatitis B virus DNA PCR product and electrochemical study of the interaction of di(2,2’-bipyridine) osmium(III) with DNA, Electroanalysis 16(19), 1642-1646 (2004) 157. Hong Zheng, Huangxian Ju, Guanghua Zhu, 双嘧达莫对胰腺癌细胞内抗肿瘤药物 6-巯基嘌呤浓度的影响及 6-巯基嘌呤的荧光分光，分析试验室 Influence of dipyridamole on 6-thiopurine concentration in Pancreas-1 tumor cells and the fluorimetric determination of 6-thiopurine, Chin. J. Anal. Lab. 23(8), 1-4 (2004) 158. Cai Xilan, Liu Xianping, Zhang Damin, Ju Huangxian*, 体液中氟乙酰胺 SPE-GC/MS 检测, 中国法医科学杂志 Determination of fluoroacetylamine in body fluid using SPE-GC/MS technique, Chinese J. Forensic Sci. 19(4), 201-204 (2004) 159. Dai Zhi-Hui, Ju Huang-Xian*, 介孔分子筛上的蛋白质直接电化学, 物理化学学报 Direct electron transfer of protein immobilized on mesoporous molecular sieves matrix, Acta Phys. Chim. Sin. 20(10), 1262-1266 (2004)

160. Vivek Babu Kandimalla, Huangxian Ju*, Molecular imprinting: a dynamic technique for diverse applications in analytical chemistry, Anal. Bioanal. Chem. 380(4), 587–605 (2004) 161. Zhijie Zhang, Yafeng Zhuang, Huangxian Ju*, 阿西美辛在高锰酸钾－亚硫酸钠体系中的流动注射化学发光分析，药学学报 Flow-injection chemiluminescent determination of acemetacin in KMnO4B -Na2SO3 system, Acta Pharm. Sinica 39(11), 925-928 (2004) 162. Shengli Liu, Jingmin Wang, Huangxian Ju, Guanghua Zhu, Dan Du, Chunfu Zhu, Hao Xu, Hai Wang, 用毛细管区带电泳方法测定胰腺癌单细胞内 5-氟尿嘧啶浓度 Determination of 5-Fluorouracil concentration in single pancreatic cancer cell based on capillary zone electrophoresis, 中国药理学通报 Chinese Pharmacological Bulletin 20(6), 717-718 (2004) 163. Guizheng Zou, Huangxian Ju*, Electrogenerated chemiluminescence from a CdSe nanocrystal film and its sensing application in aqueous solution, Anal. Chem. 76(23), 6871 - 6876 (2004) 2005 164. Huangxian Ju*, Hongtao Zhao, Electrochemical biosensors for DNA analysis, Front. Biosci. 10, 37-46 (2005) 165. Huangxian Ju*, Yongkang Ye, Yonglin Zhu, Interaction between nile blue and immobilized single- or double- stranded DNA and its application in electrochemical recognition, Electrochim. Acta 50(6), 1361-1367 (2005) 166. Jiehua Lin, Huangxian Ju*, Electrochemical and chemiluminescent immunosensors for tumor markers, Biosens. Bioelectron. 20(8), 1461-1470 (2005) 167. Baofeng Ye, Zhijie Zhang, Huangxian Ju*, Fluorescence study on the interaction between naproxen and Yeast DNA, Chin. J. Chem. 23(1), 58-62 (2005) 168. Li Tan, Yu Wang, Xiaoquan Liu, Huangxian Ju*, Jieshou Li, Simultaneous determination of L- and D-lactic acid in plasma by capillary electrophoresis, J. Chromatogr. B 814, 393-398 (2005) 169. Wei Wei, Huangxian Ju*, Application of dodecyldimethyl (2-hydroxy-3-sulfopropyl) ammonium in wall modification for capillary electrophoresis separation of proteins, Electrophoresis 26(3), 586-592 (2005) 170. Jing Chen, Dan Du, Feng Yan, Huangxian Ju*, Hongzhen Lian, Electrochemical antitumor drug sensitivity test for leukemia K562 cells at a carbon-nanotube-modified electrode, Chem. Eur. J. 11, 1467-1472 (2005) 171. Yafeng Zhuang, Damin Zhang, Huangxian Ju*, Sensitive determination of heroin based on electrogenerated chemiluminescence of tris(2,2’-bipyridyl)ruthenium(II) immobilized in zeolite Y modified carbon paste electrode, Analyst 130, 534-540 (2005) 172. Yong Cao, Yuming Zhou*, Yun Shan, Huangxian Ju*, Xuejia Xu, Preparation and characterization of grafted collagen confined in mesoporous silica, Chin. J. Inorg. Chem. 21(3), 331-336 (2005) 173. Guizheng Zou, Huangxian Ju*, Weiping Ding, Hongyuan Chen, Electrogenerated chemiluminescence of CdSe hollow spherical assemblies in aqueous system by immobilization in carbon paste, J. Electroanal. Chem. 579(1), 175-180 (2005) 174. Jianping Lei, Huangxian Ju, Osamu Ikeda*, A novel supramolecular assembly film of porphyrin bound DNA: characterization and catalytic behaviors towards nitric oxide, Sensors 5, 171-184 (2005) 175. Zhihui Dai, Huangxian Ju*, Hongyuan Chen, Mesoporous materials promoting direct electrochemistry and electrocatalysis of horseradish peroxide, Electroanalysis 17(10), 862-868 (2005) 176. Zong Dai, Jin Chen, Feng Yan, Huangxian Ju*, Electrochemical sensor for immunoassay of carcinoembryonic antigen based on thionine monolayer modified gold electrode, Cancer Detect. Prev. 29(3), 233-240 (2005) 177. Jin Chen, Feng Yan, Zong Dai, Huangxian Ju*, Reagentless amperometric immunosensor for human chorionic gonadotrophin based on direct electrochemistry of horseradish peroxidase, Biosens. Bioelectron. 21(2), 330- 336 (2005) 178. Dan Du, Shengli Liu, Jing Chen, Huangxian Ju*, Hongzhen Lian, Jianxin Li, Colloidal gold nanoparticle modified carbon paste interface for studies of tumor cell adhesion and viability, Biomaterials 26(33), 6487-6495 (2005) 179. Zhihui Dai, Xiaoxing Xu, Lina Wu, Huangxian Ju*, Detection of trace phenol based on mesoporous silica derived tyrosinase-peroxidase biosensor, Electroanalysis 17(17), 1571-1577(2005) 180. Hongtao Zhao, Zhijie Zhang, Huangxian Ju*, 基于长程电子传递的DNA直接电化学检测,Reagentless electrochemical detection of DNA PCR product based on charge transfer through DNA, 科学通报 Bull of Science 50(14), 1539-1541 (2005) 181. Dan Du, Jie Cai, Huangxian Ju*, Feng Yan, Jing Chen, Xiqun Jiang*, Hongyuan Chen, Construction of a biomimic zwitterionic interface for monitoring cell proliferation and apoptosis, Langmuir 21, 8394-8399(2005) 182. Dan Du, Huangxian Ju*, Xueji Zhang, Jing Chen, Jie Cai, Hongyuan Chen, Electrochemical immunoassay of membrane P-glycoprotein by immobilization of cells on gold nanoparticles modified on a methoxysilyl- terminated butyrylchitosan matrix, Biochemistry 44(34), 11539-11545(2005)

183. Hongtao Zhao, Zhijie Zhang, Huangxian Ju*, Direct electrochemical detection of PCR product based on charge transfer through DNA, Chin. Sci. Bull. 50(15), 1666-1668(2005) 184. Daming Zhang, Wei Sun, Zengping Yuan, Huangxian Ju*, Xuejun Shi, Chonghu Wang, Origin differentiation of a heroin sample and its acetylating agent with 13C isotope ratio mass spectrometry, Eur. J. Mass Spectrom. 11, 277-285 (2005) 185. Hongyuan Chen, Huangxian Ju, Preface for publication of the special issue of I3S 2004, SENSORS 5 (4-5): 160- 160 (2005) 186. Huangxian Ju, 电化学与化学发光免疫传感器与细胞膜受体原位免疫分析新方法, 化学传感器， Electrochemical and chemiluminescent immunosensors and novel immunoassay method for acceptors on living cell membrane, Chemical Sensors 25(2),14-16(2005) 187. Feng Yan, Jiannong Zhou, Jiehua Lin, Huangxian Ju*, Xiaoya Hu*, Flow injection immunoassay for carcinoembryonic antigen combined with time-resolved fluorometric detection, J. Immunol. Methods 305(2), 120-127 (2005) 188. Li Tan, Xiaoping Zhao, Xiaoquan Liu, Huangxian Ju*, Jieshou Li, Headspace liquid-phase microextraction of short-chain fatty acids in plasma and gas chromatography with flame ionization detection, Chromatographia 62(5/6) 305-309 (2005) 189. Yongkang Ye, Huangxian Ju*, Rapid detection of ssDNA or RNA using multi-walled carbon nanotubes modified screen-printed carbon electrode, Biosens. Bioelectron. 21(5), 735-741 (2005) 190. Yafeng Zhuang, Huangxian Ju*, Determination of reduced nicotinamide adenine dinucleotide based on immobilization of tris(2,2’-bipyridyl) ruthenium (II) in multiwall carbon nanotubes/Nafion composite membrane, Anal. Lett. 38 (13), 2077-2088 (2005) 191. Zhang Zhi-jie, Wang Feng-bin, Ju Huang-xian, 验证性实验教学中的创新意识培养，实验室研究与探索， Cultivation of creation consciousness in verification experimental teaching, Research and Exporation in Laboratory 24(12), 9-10, 17 (2005) 2006 192. Vivek Babu Kandimalla, Vijay Shyam Tripathi, Huangxian Ju*, A conductive ormosil encapsulated with ferrocene conjugate and multiwall carbon nanotubes for biosensing application, Biomaterials 27(7), 1167-1174 (2006) 193. Li’na Wu, Jin Chen, Dan Du, Huangxian Ju*, Electrochemical immunoassay for CA125 based on cellulose acetate stabilized antigen/colloidal gold nanoparticles membrane, Electrochim. Acta 51(7) 1208-1214 (2006) 194. Jin Chen, Jinhai Tang, Feng Yan, Huangxian Ju*, A gold nanoparticles/sol-gel composite architecture for encapsulation of immunoconjugate for reagentless electrochemical immunoassay, Biomaterials 27(10), 2313- 2321(2006) 195. Li Tan, Huangxian Ju*, Jieshou Li, 生物样品中短链脂肪酸的提取与测定，色谱, Extraction and determination of short-chain fatty acids in biological samples, Chin. J. Chromatogr. 24(1), 81-87 (2006) 196. V. S. Tripathi, Vivek Babu Kandimalla, Huangxian Ju*, Amperometric biosensor for hydrogen peroxide based on ferrocene-bovine serum albumin and multiwall carbon nanotube modified ormosil composite, Biosens. Bioelectron. 21(8), 1529-1535(2006) 197. Vivek Babu Kandimalla, Huangxian Ju*, Binding of acetylcholinesterase to multiwall carbon nanotube-cross- linked chitosan composite for flow-injection amperometric detection of an organophosphorous insecticide, Chem. Eur. J. 12(4), 1074-1080 (2006) 198. Tan Li, Ju Huangxian*, Li Jieshou, Zhou Min, Li Xiaoshuang, Liu Xiaoquan, 血清总磷脂脂肪酸组分的固相萃取-气相色谱法分析, 分析科学学报 Analysis of fatty acid of phospholipids in serum by solid phase extraction- gas chromatography，Chin. J. Anal. Sci. 22(2), 125-128 (2006) 199. Hongtao Zhao, Huangxian Ju*, Multilayer membranes for glucose biosensing via layer-by-layer assembly of multiwall carbon nanotubes and glucose oxidase, Anal. Biochem. 350(1), 138-144 (2006) 200. Vijay Shyam Tripathi, Vivek Babu Kandimalla, Huangxian Ju*, Preparation of ormosil and its applications in the immobilizing biomolecules, Sens. Actuat. B: Chem. 114(2), 1071-1082 (2006) 201. Jianguo Li, Qinyi Yan, Yunlong Gao, Huangxian Ju*, Electrogenerated chemiluminescence detection of amino acids based on precolumn derivatization coupled with capillary electrophoresis separation, Anal. Chem. 78, 2694-2699 (2006) 202. Jianguo Li, Fengjuan Zhao, Huangxian Ju*, Simultaneous electrochemiluminescence determination of sulpiride and tiapride by capillary electrophoresis with cyclodextrin additives, J. Chromatogr. B 835, 84-89 (2006) 203. Jin Chen, Feng Yan, Dan Du, Jie Wu, Huangxian Ju*, Electrochemical immunoassay of human chorionic gonadotrophin based on its immobilization in gold nanoparticles-chitosan membrane, Electroanalysis 18(7), 670- 676 (2006)

204. Vivek Babu Kandimalla, Vijay Shyam Tripathi, Huangxian Ju*, Immobilization of biomolecules in sol-gels: biological and analytical applications, Crit. Rev. Anal. Chem. 36 (2), 73-106 (2006) 205. Zhifeng Fu, Chen Hao, Xiaoqing Fei, Huangxian Ju*, Flow-injection chemiluminescent immunoassay for α- fetoprotein based on epoxysilane modified glass microbeads, J. Immunol. Methods 312(1-2 ), 61-67 (2006) 206. Yong Cao, Yuming Zhou, Yun Shan, Huangxian Ju*, Xuejia Xue, Triple-helix scaffolds of grafted collagen reinforced by Al2O3-ZrO2 nanoparticles, Adv. Mater. 18(14), 1838 – 1841 (2006) 207. Jianguo Li, Fengjuan Zhao, Huangxian Ju*, Simultaneous determination of psychoactive drugs in human urine by capillary electrophoresis with electrochemiluminescence detection, Anal. Chim. Acta 575(1), 57-61 (2006) 208. Shuo Wu, Hongtao Zhao, Huangxian Ju*, Chuanguo Shi, Jianwei Zhao, Electrodeposition of silver-DNA hybrid nanoparticles for electrochemical sensing of hydrogen peroxide and glucose, Electrochem. Commun. 8(8), 1197-1203 (2006) 209. Jie Wu, Jinhai Tang, Zong Dai, Feng Yan, Huangxian Ju*, Nabil El Murr, A disposable electrochemical immunosensor for flow injection immunoassay of carcinoembryonic antigen, Biosens. Bioelectron. 22(1), 102-108 (2006) 210. Jin Chen, Feng Yan, Fang Tan, Huangxian Ju*, Gold nanoparticles doped three-dimensional sol-gel matrix for amperometric human chorionic gonadotrophin immunosensor, Electroanalysis 18(17), 1696-1702 (2006) 211. Jianguo Li, Huangxian Ju*, Simultaneous determination of etamsylate, tramadol and lidocaine in human urine by capillary electrophoresis with electrochemiluminescence detection, Electrophoresis 27(17), 3467-2474 (2006) 212. Fang Tan, Feng Yan, Huangxian Ju*, A designer ormosil gel for preparation of sensitive immunosensor for carcinoembryonic antigen based on simple direct electron transfer, Electrochem. Commun. 8, 1835-1839 (2006) 213. Zhifeng Fu, Hong Liu, Huangxian Ju*, Flow-through multianalyte chemiluminescent immunosensing system with designed substrate zone-resolved technique for sequential detection of tumor markers, Anal. Chem. 78, 6999- 7005 (2006) 214. Shuizhen Zong, Yong Cao, Yuming Zhou, Huangxian Ju*, Zirconia nanoparticles enhanced grafted collagen tri- helix scaffolds for unmediated biosensing of hydrogen peroxide, Langmuir 22(21), 8915 – 8919 (2006) 215. Jiannong Zhou, Li Tan, Xuehao Wang, Huangxian Ju*, Effect of enteral nutrition formula on fat absorption and serum free fatty acid profiles in rat with short-bowel syndrome, Chin. J. Chem. 24, 1368-1374 (2006) 216. Zhifeng Fu, Jie Wu, Huangxian Ju*, 多组分免疫传感及其应用, 化学传感器 Multianalyte immunosensing and its application, Chemical Sensors 26(4), 1-11 (2006) 2007 37 papers 217. Feng Yan, Jing Chen, Huangxian Ju*, Immobilization and electrochemical behavior of gold nanoparticles modified leukemia K562 cells and application in drug sensitivity test, Electrochem. Commun. 9, 293-298 (2007) 218. Yong Cao, Yuming Zhou*, Yun Shan, Huangxian Ju*, Xuejia Xue, Preparation and characterization of grafted collagen-multiwalled carbon nanotubes composites, J. Nanosci. Nanotechnol. 7, 447–451 (2007) 219. Shuizhen Zong, Yong Cao, Yuming Zhou, Huangxian Ju*, Hydrogen peroxide biosensor based on hemoglobin modified zirconia nanoparticles-grafted collagen matrix, Anal. Chim. Acta 582, 361-366 (2007) 220. Hui Jiang, Huangxian Ju*, Enzyme-quantum dots architecture for highly sensitive electrochemiluminescence biosensing of oxidase substrates, Chem. Commun. 404–406 (2007) 221. Lina Wu, Xueji Zhang, Huangxian Ju*, Detection of NADH and ethanol based on catalytic activity of soluble carbon nanofiber with low overpotential, Anal. Chem. 79(2), 453-458 (2007) 222. Shuo Wu, Huangxian Ju*, Ying Liu, Conductive mesocellular silica-carbon nanocomposite foams for immobilization, direct electrochemistry, and biosensing of proteins, Adv. Funct. Mater. 17, 585-592 (2007) 223. Zong Dai, Simona Serban, Huangxian Ju, Nabil El Murr*, Layer-by-layer hydroxymethyl ferrocene modified sensor for one-step flow/stop-flow injection amperometric immunoassay of α-fetoprotein, Biosens. Bioelectron. 22(8) 1700-1706 (2007) 224. Shuizhen Zong, Yong Cao, Yuming Zhou, Huangxian Ju*, Reagentless biosensor for hydrogen peroxide based on immobilization of protein in zirconia nanoparticles enhanced grafted collagen matrix, Biosens. Bioelectron. 22(8) 1776-1782 (2007) 225. Lin Ding, Dan Du, Jie Wu, Huangxian Ju*, A disposable impedance sensor for electrochemical study and monitoring of adhesion and proliferation of K562 leukaemia cells, Electrochem. Commun. 9, 953-958 (2007) 226. Zhihui Dai*, Guofei Lu, Jianchun Bao, Xiaohua Huang, Huangxian Ju, Low potential detection of NADH at titanium-containing MCM-41 modified glassy carbon electrode, Electroanalysis 19(17), 604-607 (2007)

227. Shuizhen Zong, Yong Cao, Huangxian Ju*, Direct electron transfer of hemoglobin immobilized in multiwalled carbon nanotubes enhanced grafted collagen matrix for electrocatalytic detection of hydrogen peroxide, Electroanalysis 19(7-8), 841-846 (2007) 228. Lin Ding, Chen Hao, Yadong Xue, Huangxian Ju*, A bio-inspired support of gold nanoparticles-chitosan nanocomposites gel for immobilization and electrochemical study of K562 leukemia cells, Biomacromolecules 8(4), 1341-1346 (2007) 229. Ying Liu, Shuo Wu, Huangxian Ju*, Li Xu, Amperometric glucose biosensing of gold nanoparticles and carbon nanotube multilayer membranes, Electroanalysis 19(9), 986-992 (2007) 230. Lina Wu, Feng Yan, Huangxian Ju*, An amperometric immunosensor for separation-free immunoassay of CA125 based on its covalent immobilization coupled with thionine on carbon nanofiber, J. Immunol. Methods 322(1- 2), 12-19(2007) 231. Lina Wu, Xueji Zhang, Huangxian Ju*, Highly sensitive flow injection detection of hydrogen peroxide with high throughput using a carbon nanofiber-modified electrode, Analyst 132(5), 406 - 408 (2007) 232. Zhian Liu, Ming Jiang, Jianhua Zhao, Huangxian Ju*, Circulating tumor cells in perioperative esophageal cancer patients: quantitative assay system and potential clinical utility, Clin. Cancer Res. 13, 2992-2997 (2007) highlighted 233. Fang Tan, Feng Yan, Huangxian Ju*, Sensitive reagentless electrochemical immunosensor based on an ormosil sol-gel membrane for human chorionic gonadotrophin, Biosens. Bioelectron. 22, 2945-2951 (2007) 234. Chen Hao, Feng Yan, Lin Ding, Yadong Xue, Huangxian Ju*, A self-assembled monolayer based electrochemical immunosensor for detection of leukemia K562A cells, Electrochem. Commun. 9, 1359-1364 (2007) 235. Shuizhen Zong, Yong Cao, Huangxian Ju*, Amperometric biosensor for hydrogen peroxide based on myoglobin doped multiwalled carbon nanotube enhanced grafted collagen matrix, Anal. Lett. 40, 1556-1568 (2007) 236. Chen Hao, Lin Ding, Xueji Zhang, Huangxian Ju*, Biocompatible conductive architecture of carbon nanofiber- doped chitosan prepared with controllable electrodeposition for cytosensing, Anal. Chem. 79(12), 4442-4447 (2007), highlighted in AC 237. Zhihui Dai*, Guofei Lu, Jianchun Bao, Xiaohua Huang, Huangxian Ju, Detection of NADH and ethanol at titanium containing MCM-41 with low overpotential, Electroanalysis 19(15), 1591-1596 (2007) 238. Jianguo Li, Yuan Chun, Huangxian Ju*, Simultaneous electrochemiluminescence detection of anisodamine, atropine and scopolamine in Flos Daturae by capillary electrophoresis using -cyclodextrin as additive, Electroanalysis 19(15), 1569-1574 (2007) 239. Jie Wu ， Feng Yan, Jinhai Tang, Chun Zhai, Huangxian Ju*, A disposable multianalyte electrochemical immunosensor array for automated simultaneous determination of tumor markers, Clin. Chem. 53, 1495-1502 (2007) 240. Jie Wu, Zhifeng Fu, Feng Yan*, Huangxian Ju*, Biomedical and clinical applications of immunoassays and immunosensors for tumor markers, Trac-Trend. Anal. Chem. 26/7, 679-688 (2007) 241. Jianguo Li, Ying Liu, Huangxian Ju*, 季胺-辣根过氧化物酶-过氧化氢显色新体系及其在酶活性检测中的应用, A novel tetrabase-horseradish Peroxidase-H2O2 spectrophotometric system and its application to detection of enzyme activity, 化学学报 Acta Chim. Sinica 65(15), 1499-1503 (2007) 242. Jie Wu, Zhijie Zhang, Zhifeng Fu, Huangxian Ju*, A disposable two-throughput electrochemical immunosensor chip for simultaneous multianalyte determination of tumor markers, Biosens. Bioelectron. 23(1), 114-120 (2007) 243. Hui Jiang, Huangxian Ju*, Electrochemiluminescence sensors for scavengers of hydroxyl radical based on its annihilation in CdSe quantum dots film/peroxide system. Anal. Chem. 79(17), 6690-6696 (2007) 244. Lina Wu, Xueji Zhang, Huangxian Ju*, Amperometric glucose sensor based on catalytic reduction of dissolved oxygen at soluble carbon nanofiber, Biosens. Bioelectron. 23(4), 479-484 (2007) 245. Zhifeng Fu, Zhanjun Yang, Jinhai Tang, Hong Liu, Feng Yan*, Huangxian Ju*, Channel and substrate zone two- dimensional resolution for chemiluminescent multiplex immunoassay, Anal. Chem. 79(19), 7376-7382 (2007) 246. Ying Liu, Yilong Yan, Jianping Lei*, Fan Wu, Huangxian Ju*, Functional multiwalled carbon nanotube nanocomposite with iron picket-fence porphyrin and its electrocatalytic behavior, Electrochem. Commun. 9, 2564-2570 (2007) 247. Ruizhuo Ouyang, Jianping Lei, Huangxian Ju*, Yadong Xue, A molecularly imprinted copolymer designed for enantioselective recognition of glutamic acid, Adv. Funct. Mater. 17, 3223-3230 (2007) 248. Xuan Liu, Hui Jiang, Jianping Lei, Huangxian Ju*, Anodic electrochemiluminescence of CdTe quantum dots and its energy transfer for detection of catechol derivatives, Anal. Chem. 79(21), 8055-8060 (2007)

249. Zhifeng Fu, Hong Liu, Zhanjun Yang, Huangxian Ju*, Recent developments in multianalyte immunoassay, Current Trends Biotechnol. Pharm., 1(1), 1-17 (2007) 250. Yong Cao, Yuming Zhou*, Yun Shan, Huangxian Ju*, Xuejia Xue, Al2O3/SnO2 co-nanoparticle modified grafted collagen for improving thermal stability and infrared emissivity, Chin. J. Chem. 25(12), 1849-1853 (2007) 251. Lina Wu, Mike McIntosh, Xueji Zhang*, Huangxian Ju*, Amperometric sensor for ethanol based on one-step electropolymerization of thionine-carbon nanofiber nanocomposite containing alcohol oxidase. Talanta 74, 387- 393 (2007) 252. Chun Zhai, Chen Li, Wei Qiang, Jianping Lei, Xiaodong Yu, Huangxian Ju*, Amperometric detection of carbohydrates with a portable silicone/quartz capillary microchip by designed fracture sampling, Anal. Chem. 79, 9427-9432 (2007) 253. Feng Yan, Huangxian Ju*, 免疫分析与细胞检测新原理与新方法研究, 化学进展 Novel concepts and approach of immunoassay and cellular analysis, Progress in Chem. 19(12), 1852-1860 (2007) in Special Issue of Chemistry Biology 2008 25 papers 254. Cunwang Ge, Min Xu, Jing Liu, Jianping Lei, Huangxian Ju*, Facile synthesis and application of highly luminescent CdTe quantum dots with an electrogenerated precursor, Chem. Commun. 450-452 (2008) 255. Shuo Wu, Jie Wu, Yiying Liu, Huangxian Ju*, Conductive and highly catalytic nanocage for assembly and improving function of enzyme, Chem. Mater. 20(4), 1397-1403 (2008) 256. Ying Liu, Jianping Lei, Huangxian Ju*, Amperometric sensor for hydrogen peroxide based on electric wire composed of horseradish peroxidase and toluidine blue-multiwalled carbon nanotubes nanocomposite, Talanta 74(4), 965-970 (2008) 257. Zhifeng Fu, Feng Yan, Hong Liu, Zhanjun Yang, Huangxian Ju*, Channel-resolved multianalyte immunosensing system for flow-through chemiluminescent detection of α-fetoprotein and carcinoembryonic antigen, Biosens. Bioelectron. 23, 1063-1069 (2008) 258. Zhihui Dai*, Jianchun Bao, Xiaodi Yang, Huangxian Ju*, A bienzyme channeling glucose sensor with a wide concentration range based on co-entrapment of enzymes in SBA-15 mesopores, Biosens. Bioelectron. 23, 1070-1076 (2008) 259. Zhian Liu, Ming Jiang, Feng Yan, Lin Xu, Jianhua Zhao*, Huangxian Ju*, Multipoint quantification of multimarker genes in peripheral blood and micrometastasis characteristic in peri-operative esophageal cancer patients, Cancer Lett. 261(1), 46-54 (2008) 260. Shuo Wu, Yiying Liu, Jie Wu, Huangxian Ju*, Prussian blue nanoparticles doped nanocage for controllable immobilization and selective biosensing of enzyme, Electrochem. Commun. 10(3), 397-401 (2008) 261. Zhifeng Fu, Feng Yan,* Hong Liu, Jiehua Lin, Huangxian Ju*, A channel-resolved approach coupled with magnet- captured technique for multianalyte chemiluminescent immunoassay, Biosens. Bioelectron. 23(10), 1422-1428 (2008) 262. Wenwen Tu, Jianping Lei*, Huangxian Ju*, Noncovalent nanoassembly of porphyrin on single-walled carbon nanotubes for electrocatalytic reduction of nitric oxide and oxygen, Electrochem. Commun. 10, 766-769 (2008) 263. Wei Cheng, Lin Ding, Jianping Lei, Shijia Ding*, Huangxian Ju*, Effective cell capture with tetrapeptide- functionalized carbon nanotubes and dual signal amplification for cytosensing and evaluation of cell surface carbohydrate, Anal. Chem. 80, 3867-3872 (2008) 264. Lin Ding, Wei Cheng, Xiaojian Wang, Shijia Ding, Huangxian Ju*, Carbohydrate monolayer strategy for electrochemical assay of cell surface carbohydrate, J. Am. Chem. Soc. 130, 7224-7225 (2008) 265. Zhanjun Yang, Zhifeng Fu, Feng Yan*, Hong Liu, Huangxian Ju*, A chemiluminescent immunosensor based on antibody immobilized carboxylic resin beads coupled with micro-bubble accelerated immunoreaction for fast flow- injection immunoassay, Biosens. Bioelectron. 24, 35-40 (2008) 266. Xuan Liu, Huangxian Ju*, Coreactant enhanced anodic electrochemiluminescence of CdTe quantum dots at low potential for sensitive biosensing amplified by enzymatic cycle, Anal. Chem. 80(14), 5377-5382 (2008) 267. Hong Liu, Zhifeng Fu, Zhanjun Yang, Yan Feng*, Huangxian Ju*, Sampling-resolution strategy for one-way multiplexed immunoassay with sequential chemiluminescent detection, Anal. Chem. 80(14), 5654-5659 (2008) 268. Cunwang Ge, Ming Xu, Jinhuai Fang, Jianping Lei, Huangxian Ju*, Luminescent cadmium sulfide nanochains templated on unfixed deoxyribonucleic acid and their fractal alignment by droplet dewetting, J. Phys. Chem. C 112(29), 10602-10608 (2008) 269. Yuming Zhou*, Yun Shan, Yanqing Sun, Huangxian Ju, Adsorption of collagen to indium oxide nanoparticles and infrared emissivity study thereon, Mater. Res. Bull. 43(8-9), 2105-2112 (2008)

270. Jie Wu, Yuetian Yan, Feng Yan*, Huangxian Ju*, Electric field-driven strategy for multiplexed detection of protein biomarkers using a disposable reagentless electrochemical immunosensor array, Anal. Chem. 80(15), 6072-6077 (2008) 271. Jie Wu, Feng Yan*, Xiaoqing Zhang, Yuetian Yan, Jinhai, Tang, Huangxian Ju*, Disposable reagentless electrochemical immunosensor array based on a biopolymer/sol-gel membrane for simultaneous measurement of several tumor markers, Clin. Chem. 54(9), 1481-1488 (2008) 272. Lina Wu, Jianping Lei*, Xueji Zhang, Huangxian Ju*, Biofunctional nanocomposite of carbon nanofiber with water-soluble porphyrin for highly sensitive ethanol biosensing. Biosens. Bioelectron. 24, 644-649 (2008) 273. Xuan Liu, Lingxiao Cheng, Jianping Lei, Huangxian Ju*, Dopamine detection based on its quenching effect on the anodic electrochemiluminescence of CdSe quantum dots, Analyst 133, 1161-1163 (2008) cover paper 274. Peixi Yuan, Ying Zhuo, Yaqin Chai, Huangxian Ju*, Dendritic silver/silicon dioxide nanocomposite modified electrodes for electrochemical sensing of hydrogen peroxide, Electroanalysis 20(17), 1839-1844 (2008) 275. Ruizhuo Ouyang, Jianping Lei, Huangxian Ju*, Surface molecularly imprinted nanowire for protein specific recognition, Chem. Commun. 5761-5763 (2008) 276. Lin Ding, Dan Du, Xueji Zhang*, Huangxian Ju*, Trends in cell-based electrochemical biosensors, Curr. Med. Chem. 15(30), 3160-3170 (2008) 277. Zhanjun Yang, Zhuoying Xie, Hong Liu, Feng Yan*, Huangxian Ju*, Streptavidin-functionalized three- dimensional ordered nanoporous silica film for highly efficient chemiluminescent immunosensing, Adv. Funct. Mater. 18, 3991-3998 (2008) 278. Zhijie Zhang*, Fengbin Wang, Huangxian Ju, 创新教育氛围下的 TA 多元化培养方式探讨，大学化学 Discussion on the multitraining ways of teaching assistants under creative eduction, University Chemistry 23(6), 19-22 (2008) 279. Jianmin Xu, Honggang Zhang, Xiaoqing Fei, Huangxian Ju, Jie Zheng, Shengli Liu*, 干扰hENT1表达增加5-FU 在胰腺癌SW1990细胞内浓度, 中国药理学通报 Interfering hENT 1 expression raising 5-FU concentration in pancreatic cancer SW1990 cells, Chinese Pharmacological Bulletin 24(10), 1351-1355 (2008) 280. Honggang Zhang, Jianmin Xu, Xiaoqing Fei, Huangxian Ju, Shengli Liu*, 下调 hENT1 可抑制胰腺癌细胞株 Sw1990对吉西他滨的跨膜转运, 中国药科大学学报 Down-regulating hENT1 inhibits gemcitabine transport in pancreatic cancer cell line Sw1990, J. China Pharmac. Univ. 39(5), 457-462 (2008) 2009 20 papers 281. Wenwen Tu, Jianping Lei*, Huangxian Ju*, Functionalization of carbon nanotubes with water-insoluble porphyrin in ionic liquid: direct electrochemistry and highly sensitive amperometric biosensing for trichloroacetic acid, Chem. Eur. J. 15, 779-784 (2009) 282. Jing Zhang, Jianping Lei, Yiyin Liu, Jianwei Zhao*, Huangxian Ju*, Highly sensitive amperometric biosensors for phenols based on polyaniline-ionic liquid-carbon nanofiber composite, Biosens. Bioelectron. 24, 1858- 1863 (2009) 283. Juan You, Weiping Ding, Shijia Ding*, Huangxian Ju*, Direct electrochemistry of hemoglobin immobilized on colloidal gold-hydroxyapatite nanocomposite for electrocatalytic detection of hydrogen peroxide, Electroanalysis 21(2), 190-195 (2009) 284. Xuan Liu, Liang Guo, Lingxiao Cheng, Huangxian Ju*, Determination of nitrite based on its quenching effect on anodic electrochemiluminescence of CdSe quantum dots, Talanta 78, 691-694 (2009) 285. Lin Ding, Chen Hao, Xueji Zhang, Huangxian Ju*, Carbon nanofiber doped polypyrrole nanoscaffold for electrochemical monitoring of cell adhesion and proliferation, Electrochem. Commun. 11, 760-763(2009) 286. Zhihui Dai, Shaohua Liu, Jianchun Bao*, Huangxian Ju* (Jui HX), Nanostructured FeS as a mimic peroxidase for biocatalysis and biosensing, Chem. Eur. J. 15(17), 4321-4326 (2009) 287. Chuan Leng, Xiaoqing Zhang, Huangxian Ju*(Jue HX), 微流控芯片上的免疫分析方法 , 化学进展 Microfluidic chip-based immunoassay, Progress in Chem. 21(4), 687-695 (2009) 288. Chun Zhai, Wei Qiang, Jianping Lei, Huangxian Ju*, Highly resolved separation and sensitive amperometric detection of amino acids with an assembled microfluidic device, Electrophoresis 30, 1490-1496 (2009) 289. Hong Liu, Zhanjun Yang, Feng Yan*, Yueming Xu, Huangxian Ju*, Three-minute-long chemiluminescence immunoassay using dually accelerated immunoreaction by infrared heating and passive mixing, Anal. Chem. 81 (10), 4043-4047 (2009) 290. Feng Yan, Jie Wu, Fang Tan, Yuetian Yan, Huangxian Ju*, A rapid and simple method for ultrasensitive electrochemical immunoassay of protein by an electric field-driven strategy, Anal. Chim. Acta 644, 36-41 (2009) 291. Wenwen Tu, Jianping Lei,* Lin Ding, Huangxian Ju*, Sandwich nanohybrid of single-walled carbon nanohorns- TiO2-porphyrin for electrocatalysis and amperometric biosensing towards chloramphenicol, Chem. Commun.

4227-4229 (2009) 292. Zhanjun Yang, Hong Liu, Chen Zong, Feng Yan*, Huangxian Ju*, Automated support-resolution strategy for a one-way chemiluminescent multiplex immunoassay, Anal. Chem. 81 (13), 5484-5489 (2009) hightlighted 293. Wei Cheng, Lin Ding, Shijia Ding, Yibing Yin, Huangxian Ju*, A simple electrochemical cytosensor array for dynamic analysis of carcinoma cell surface glycans, Angew. Chem. Int. Ed. 48(35), 6465-6468 (2009) (VIP) 294. Wei Qiang, Chun Zhai, Jianping Lei, Chaojin Song, Daming Zhang, Jin Sheng, Huangxian Ju*, Disposable microfluidic device with ultraviolet detection for highly resolved screening of illicit drugs, Analyst 134, 1834- 1839 (2009) 295. Shengyuan Deng, Guoqiang Jian, Jianping Lei*, Zheng Hu, Huangxian Ju*, A glucose biosensor based on direct electrochemistry of glucose oxidase immobilized on nitrogen-doped carbon nanotubes, Biosens. Bioelectron. 25, 373-377 (2009) 296. Liang Guo, Xuan Liu, Zheng Hu, Shengyuan Deng, Huangxian Ju*, Electrochemiluminescence of CdSe quantum dots composited with nitrogen-doped carbon nanotubes, Electroanalysis 21, 2495-2498 (2009) 297. Lin Ding, Wei Cheng, Xiaojian Wang, Yadong Xue, Jianping Lei, Yibing Yin, Huangxian Ju*, A label-free strategy for facile electrochemical analysis of dynamic glycan expression on living cells, Chem. Commun. 7161- 7163 (2009) 298. Feng Yan*, Zhian Liu, Jianhua Zhao, Huangxian Ju*, Dissemination profile of perioperative tumor cells in peripheral blood of colorectal cancer patients detected by multiple marker genes, Sci. China B 52(12), 2257- 2263 (2009) 299. Guosong Lai, Feng Yan, Huangxian Ju*, Dual signal amplification of glucose oxidase-functionalized nanocomposites as a trace label for ultrasensitive simultaneous multiplexed electrochemical detection of tumor markers, Anal. Chem. 81(23), 9730-9736 (2009) 300. Ping Qu, Jianping Lei, Ruizhuo Ouyang, Huangxian Ju*, Enantioseparation and amperometric detection of chiral compounds by in situ molecular imprinting on the microchannel wall, Anal. Chem. 81(23), 9651-9656 (2009) 2010 31 papers 301. Chun Zhai, Wei Qiang, Jin Sheng, Jianping Lei, Huangxian Ju*, Pretreatment-free fast ultraviolet detection of melamine in milk products with a disposable microfluidic device, J. Chromatogr. A 1217, 785-789 (2010) 302. Jing Zhang, Jianping Lei, Chuanlai Xu, Lin Ding, Huangxian Ju*, Carbon nanohorns sensitized electrochemical immunosensor for rapid detection of microcystin-LR, Anal. Chem. 82(3), 1117–1122 (2010) 303. Lin Ding, Quanjiang Ji, Ruocan Qian, Wei Cheng, Huangxian Ju*, Lectin-based nanoprobes functionalized with enzyme for highly sensitive electrochemical monitoring of dynamic carbohydrate expression on living cells, Anal. Chem. 82(4), 1292-1298 (2010) 304. Wenwen Tu, Jianping Lei*, Guoqiang Jian, Zheng Hu, Huangxian Ju*, Noncovalent assembly of Picket-fence porphyrins on nitrogen-doped carbon nanotubes for highly efficient catalysis and biosensing, Chem. Eur. J. 16, 4120-4126 (2010) 305. Haifeng Dong, Feng Yan*, Hanxu Ji, Danny K. Y. Wong*, Huangxian Ju*, Quantum-dot-functionalized poly(styrene-co-acrylic acid) microbeads: Step-wise self-assembly, characterization, and applications for sub- femtomolar electrochemical detection of DNA hybridization, Adv. Funct. Mater. 20, 1173-1179 (2010) 306. Wei Cheng, Feng Yan, Lin Ding, Huangxian Ju*, Yibin Yin*, Cascade signal amplification strategy for sub- attomolar protein detection by rolling circle amplification and quantum dots tagging, Anal. Chem. 82(8), 3337- 3342 (2010) 307. Lingxiao Cheng, Xuan Liu, Jianping Lei*, Huangxian Ju*, Low-potential electrochemiluminescent sensing based on surface unpassivation of CdTe quantum dots and competition of analyte cation to stabilizer, Anal. Chem. 82(8), 3359-3364 (2010) 308. En Han, Lin Ding, Hongzhen Lian, Huangxian Ju*, Cytosensing and dynamic monitoring of cell surface carbohydrate expression by electrochemiluminescence of quantum dots, Chem. Commun. 46, 5446-5448 (2010) 309. Ruizhuo Ouyang, Jianping Lei*, Huangxian Ju*, Artificial receptor-functionalized nanoshell: facile preparation, fast separation and specific protein recognition, Nanotechnology 21, 185502 (9pp) (2010) 310. Chun Zhai, Jin Sheng, Wei Qiang, Jianping Lei, Huangxian Ju*, Ultraviolet detection of amino acids based on their on-column conjugation with cupric cation using a disposable electrophoresis microdevice, Talanta 82, 67- 71 (2010) 311. Chuan Leng, Guosong Lai, Feng Yan*, Huangxian Ju*, Gold nanoparticle as an electrochemical label for inherently crosstalk-free multiplexed immunoassay on a disposable chip, Anal. Chim. Acta 666, 97-101 (2010) 312. Jianping Lei, Huangxian Ju*, Nanotubes in biosensing, WIREs Nanomed. Nanobiotechnol. 2(5), 496-509 (2010) 313. Wenwen Tu, Jianping Lei*, Siyuan Zhang, Huangxian Ju*, Characterization, direct electrochemistry, and

amperometric biosensing of graphene by noncovalent functionalization with picket-fence porphyrin, Chem. Eur. J. 16, 10771-10777 (2010) 314. Yiying Liu, Jianping Lei, Huangxian Ju*, CuO-doped mesoporous silica hybrid for rapid and sensitive amperometric detection of phenolic compounds, Electroanalysis 22(20), 2407-2412 (2010) 315. Xu Xu, Lin Ding, Yadong Xue, Huangxian Ju*, A simple fluorescent strategy for in situ evaluation of cell surface carbohydrate with a quantum dot-lectin nanoprobe, Analyst 135(8), 1906-1908 (2010) cover paper 316. Haifeng Dong, Wenchao Gao, Feng Yan*, Hanxu Ji, Huangxian Ju*, Fluorescence resonance energy transfer between quantum dots and graphene oxide for sensing biomolecules, Anal. Chem. 82(13), 5511-5517 (2010) 317. Lin Ding, Ruocan Qian, Yadong Xue, Wei Cheng, Huangxian Ju*, In situ scanometric assay of cell surface carbohydrate by glyconanoparticle-aggregation-regulated silver enhancement, Anal. Chem. 82(13), 5804-5809 (2010) hightlighted 318. Yadong Xue, Lin Ding, Jianping Lei, Huangxian Ju*, A simple electrochemical lectin-probe for in situ homogeneous cytosensing and facile evaluation of cell surface glycan, Biosens. Bioelectron. 26, 169-174 (2010) 319. Zhanjun Yang, Chen Zong, Feng Yan*, Huangxian Ju*, Automated chemiluminescent dual-analyte immunoassay based on resolved immunosensing channels, Talanta 82, 1462-1467 (2010) 320. Xuan Liu, Lingxiao Cheng, Jianping Lei, Hui Liu, Huangxian Ju*, Formation of surface traps on quantum dots by bidentate chelation and their application in low-potential electrochemiluminescent biosensing, Chem. Eur. J. 16, 10764 -10770 (2010) (VIP and inside cover) 321. Yadong Xue, Lin Ding, Jianping Lei, Feng Yan, Huangxian Ju*, In situ electrochemical imaging of membrane glycan expression on micropatterned adherent single cells, Anal. Chem. 82(17), 7112-7118 (2010) hightlighted 322. Ping Qu, Jianping Lei, Lei Zhang, Ruizhuo Ouyang, Huangxian Ju*, Molecularly imprinted magnetic nanoparticles as tunable stationary phase located in microfluidic channel for enantioseparation, J. Chromatogr. A 1217, 6115-6121 (2010) 323. Xuan Liu, Yangyang Zhang, Jianping Lei, YadongXue, Lingxiao Cheng, Huangxian Ju*, Quantum dots based electrochemiluminescent immunosensor by coupling enzymatic amplification with self-produced coreactant from oxygen reduction, Anal. Chem. 82(17), 7351-7356 (2010) hightlighted 324. Sheng Tang, Xizhang Wang, Jianping Lei*, Zheng Hu, Shengyuan Deng, Huangxian Ju*, Pt-dispersed flower-like carbon nanosheet aggregation for low-overpotential electrochemical biosensing, Biosens. Bioelectron. 26, 432-436 (2010) 325. Jing Zhang, Jianping Lei, Rong Pan, Yadong Xue, Huangxian Ju*, Highly sensitive electrocatalytic biosensing of hypoxanthine based on functionalization of graphene sheets with water-soluble conducting graft copolymer, Biosens. Bioelectron. 26, 371-376 (2010) 326. Wei Cheng, Lin Ding, Yunlong Chen, Feng Yan, Huangxian Ju*, Yibing Yin*, A facile scanometric strategy for ultrasensitive detection of protein using aptamer-initiated rolling circle amplification, Chem. Commun. 46, 6720-6722 (2010) 327. Jin Sheng, Jianping Lei, Huangxian Ju*, Chaojin Song, Daming Zhang, Rapid ultraviolet monitoring of multiple psychotropic drugs with a renewable microfluidic device, Anal. Chim. Acta 679, 1-6 (2010) as a featured article and cover paper 328. Yadong Xue, Jianping Lei, Xu Xu, Lin Ding, Chun Zai, Feng Yan, Huangxian Ju*, Real-time monitoring of cell viability by its nanoscale height change with oxygen as endogenous indicator, Chem. Commun. 46, 7388-7390 (2010) 329. Wenwen Tu, Yitong Dong, Jianping Lei*, Huangxian Ju*, Low-potential photoelectrochemical biosensing using porphyrin-functionalized TiO2 nanoparticles, Anal. Chem. 82(20), 8711-8716 (2010) 330. Hongfa Chang, Xianping Liu, Daming Zhang*, Huangxian Ju, 氟乙酰胺代谢产物氟离子检测芯片的研究, 中国法医学杂志 Study on chip determining of F- of the metabolizability of fluoroacetamide, Chinese Journal of Forensic Medicine 25(3), 175-177 (2010) 331. Shuizhen Zong, Rongjing Cui, Lei Fei, Weiwei Li, Huangxian Ju*, 肌红蛋白在氧化镍纳米粒子中的固定及新型生物传感器的制备, 分析化学 38(11), 1533-1537 (2010), Immobilization of myoglobin on NiO nanoparticles matrix for preparation of novel biosensor, Chin. J. Anal. Chem. 38(11), 1533-1537 (2010) 2011 34 papers 332. Jing Zhang, Jianping Lei, Rong Pan, Chuan Leng, Zheng Hu, Huangxian Ju*, In situ assembly of gold nanoparticles on nitrogen-doped carbon nanotubes for sensitive immunosensing of microcystin-LR, Chem. Commun. 47(2), 668-670 (2011)

333. En Han, Lin Ding, Shi Jin, Huangxian Ju*, Electrochemiluminescent biosensing of carbohydrate-functionalized CdS nanocomposites for in situ label-free analysis of cell surface carbohydrate, Biosens. Bioelectron. 26, 2500- 2505 (2011) 334. Yadong Xue, Lei Bao, Xirui Xiao, Lin Ding, Jianping Lei, Huangxian Ju*, Noncovalent functionalization of carbon nanotubes with lectin for label-free dynamic monitoring of cell-surface glycan expression, Anal. Biochem. 410(1), 92-97 (2011) 335. Ping Qu, Jianping Lei, Jin Sheng, Lei Zhang, Huangxian Ju*, Simultaneous multiple enantioseparation with a one- pot imprinted microfluidic channel by microchip capillary electrochromatography, Analyst 136(5), 920-926 (2011) 336. Wei Cheng, Yunlong Chen, Feng Yan, Lin Ding, Shijia Ding, Huangxian Ju*, Yibing Yin*, Ultrasensitive scanometric strategy for detection of matrix metalloproteinases using a histidine tagged peptide-Au nanoparticle probe, Chem. Commun. 47(10), 2877-2879 (2011) 337. Haifeng Dong, Lin Ding, Feng Yan*, Hanxu Ji, Huangxian Ju*, The use of polyethylenimine-grafted graphene nanoribbon for cellular delivery of locked nucleic acid modified molecular beacon for recognition of microRNA, Biomaterials 32, 3875-3882 (2011) 338. Jie Li, Wenwen Tu, Jianping Lei*, Sheng Tang, Huangxian Ju*, Porphyrin-functionalized gold nanoparticles for selective electrochemical detection of peroxyacetic acid, Electrochim. Acta 56, 3159-3163 (2011) 339. Lin Ding, Xirui Xiao, Yunlong Chen, Ruocan Qian, Lei Bao, Huangxian Ju*, Competition-based transfer of carbohydrate expression information from a cell-adhered surface to a secondary surface, Chem. Commun. 47, 3742-3744(2011) 340. Guosong Lai, Feng Yan, Jie Wu, Chuan Leng, Huangxian Ju*, Ultrasensitive multiplexed immunoassay with electrochemical stripping analysis of silver nanoparticles catalytically deposited by gold nanoparticles and enzymatic reaction, Anal. Chem. 83, 2726–2732 (2011) 341. Wenchao Gao, Haifeng Dong, Jianping Lei*, Hanxu Ji, Huangxian Ju*, Signal amplification of streptavidin- horseradish peroxidase functionalized carbon nanotubes for amperometric detection of attomolar DNA, Chem. Commun. 47, 5220-5222 (2011) 342. Guosong Lai, Jie Wu, Chuan Leng, Huangxian Ju*, Feng Yan*, Disposable immunosensor array for ultrasensitive detection of tumor markers using glucose oxidase-functionalized silica nanosphere tags, Biosens. Bioelectron. 26, 3782-3787 (2011) 343. Feng Yan*, Xuyan Tan, Yao Geng, Huangxian Ju, Yanfang Gao, Mingchen Zhu, Inhibition effect of siRNA- downregulated UHRF1 on breast cancer growth, Cancer Biother. Radio. 26(2), 183-189 (2011) 344. Shou-Qing Liu, Hua Li, Wei-Hui Sun, Xiao-Mei Wang, Zhi-Gang Chen, Jing-Juan Xu, Huang-Xian Ju, Hong- Yuan Chen, Photoinducedly electrochemical preparation of Prussian blue film and electrochemical modification of the film with cetyltrimethylammonium cation, Electrochim. Acta 56, 4007-4014 (2011) 345. Siyuan Zhang, Sheng Tang, Jianping Lei*, Haifeng Dong, Huangxian Ju*, Functionalization of graphene nanoribbons with porphyrin for electrocatalysis and amperometric biosensing, J. Electroanal. Chem. 656, 285- 288 (2011) 346. Yongjun Chen*, S. K. Lunsford, Yongcheng Song, Huangxian Ju, P. Falaras, V. Likodimos, A. G. Kontos, D. D. Dionysiou, Synthesis, characterization and electrochemical properties of mesoporous zirconia nanomaterials prepared by self-assembling sol-gel method with Tween 20 as a template, Chem. Eng. J. 170, 518-524 (2011) 347. Ping Qu, Lei Zhang, Jin Sheng, Jianping Lei, Huangxian Ju*, Convenient enantioseparation by monolithic imprinted capillary clamped in a chip with electrochemical detection, Electrophoresis 32, 1522–1529 (2011) 348. Shengyuan Deng, Jianping Lei, Lingxiao Cheng, Yangyang Zhang, Huangxian Ju*, Amplified electrochemiluminescence of quantum dots by electrochemically reduced graphene oxide for nanobiosensing of acetylcholine, Biosens. Bioelectron. 26, 4552-4558 (2011) 349. Dajie Lin, Jie Wu, Feng Yan, Shengyuan Deng, Huangxian Ju*, Ultrasensitive immunoassay of protein biomarker based on electrochemiluminescent quenching of quantum dots by hemin bio-bar-coded nanoparticle tags, Anal. Chem. 83, 5214-5221 (2011) 350. Huangxian Ju*, Sensitive biosensing strategy based on functional nanomaterials, Sci. China Chem 54(8), 1202– 1217 (2011) 351. Chuan Leng, Jie Wu, Qiunan Xu, Guosong Lai, Huangxian Ju*, Feng Yan*, A highly sensitive disposable immunosensor through direct electro-reduction of oxygen catalyzed by palladium nanoparticle decorated carbon nanotube label, Biosens. Bioelectron. 27, 71-76 (2011) 352. Guosong Lai, Jie Wu, Huangxian Ju*, Feng Yan*, Streptavidin-functionalized silver-nanoparticle-enriched carbon nanotube tag for ultrasensitive multiplexed detection of tumor markers, Adv. Funct. Mater. 21, 2938-2943 (2011) 353. Wenwen Tu, Jianping Lei*, Peng Wang, Huangxian Ju*, Photoelectrochemistry of free-base-porphyrin-

functionalized zinc oxide nanoparticles and their applications in biosensing, Chem. Eur. J. 17, 9440-9447 (2011) 354. Jianping Lei, Huangxian Ju*, Fundamentals and bioanalytical applications of functional quantum dots as electrogenerated emitters of chemiluminescence, Trends Anal. Chem. 30(8), 1351-1359 (2011) 355. Yangyang Zhang, Shengyuan Deng, Jianping Lei, Qiunan Xu, Huangxian Ju*, Carbon nanospheres enhanced electrochemiluminescence of CdS quantum dots for biosensing of hypoxanthine, Talanta 85, 2154-2158 (2011) 356. En Han, Lin Ding, Huangxian Ju*, Highly sensitive fluorescent analysis of dynamic glycan expression on living cells using glyconanoparticles and functionalized quantum dots, Anal. Chem. 83, 7006-7012 (2011) 357. Faten Divsar, Huangxian Ju*, Electrochemiluminescence detection of near single DNA molecules by using quantum dots-dendrimer nanocomposites for signal amplification, Chem. Commun. 47 (35), 9879-9881 (2011) 358. Chen Wang, Jie Wu, Chen Zong Huangxian Ju*, Feng Yan*, Highly sensitive rapid chemiluminescent immunoassay using the DNAzyme label for signal amplification, Analyst 136, 4295-4300 (2011) 359. Wenwen Tu, Jianping Lei*, Huangxian Ju*, 卟啉纳米组装与生物传感, 化学进展, Nanoassembly and biosensing of porphyrins, Prog. Chem. 23(10), 2113-2118 (2011) 360. Hanxu Ji, Haifeng Dong, Feng Yan, Jianping Lei, Ling Ding, Wenchao Gao, Huangxian Ju*, Visual scanometric detection of DNA through silver enhancement regulated by gold-nanoparticle aggregation with a molecular beacon as the trigger, Chem. Eur. J. 17(40), 11344–11349 (2011) 361. Jiang Yang, Shengyuan Deng, Jianping Lei, Huangxian Ju*, Sundaram Gunasekaran*, Electrochemical synthesis of reduced graphene sheet-AuPd alloy nanoparticle composites for enzymatic biosensing, Biosens. Bioelectron. 29(1), 159-166 (2011) 362. Zhanjun Yang, Chen Zong, Huangxian Ju*, Feng Yan*, Streptavidin-functionalized capillary immune microreactor for highly efficient chemiluminescent immunoassay, Anal. Chim. Acta 706, 143-148 (2011) 363. Xuan Liu, Zhentao Hou, Jianping Lei, Huangxian Ju*, Jingxuan Cai, Jianyi Shen, High electron transfer efficiency of titania dioxide nanotube for low potential electrochemiluminescent biosensing, Electroanalysis 23, 2629-2632 (2011) 364. Shengyuan Deng, Zhentao Hou, Jianping Lei, Dajie Lin, Zheng Hu, Feng Yan, Huangxian Ju*, Signal amplification by adsorption-induced catalytic reduction of dissolved oxygen on nitrogen-doped carbon nanotubes for electrochemiluminescent immunoassay, Chem. Commun. 47(44), 12107-12109 (2011) 365. Lin Ding, Huangxian Ju*, Biofunctionalization of nanoparticles for cytosensing and cell surface carbohydrate assay. J. Mater. Chem. 21(45), 18154-18173 (2011) Feature Article 2012 38 papers 366. Jin Sheng, Lei Zhang, Jianping Lei, Huangxian Ju*, Fabrication of tunable microreactor with enzyme modified magnetic nanoparticles for microfluidic electrochemical detection of glucose, Anal. Chim. Acta 709, 41-46 (2012) as a featured article and cover paper 367. Lingxiao Cheng, Shengyuan Deng, Jianping Lei*, Huangxian Ju*, Disposable electrochemiluminescent biosensor using bidentate-chelated CdTe quantum dots as emitters for sensitive detection of glucose, Analyst 137, 140- 144 (2012) 268. Shuo Wu*, Xiaoqin Lan, Feifei Huang, Zhengzi Luo, Huangxian Ju*, Changgong Meng, Chunying Duan, Selective electrochemical detection of cysteine in complex serum by graphene nanoribbon, Biosens. Bioelectron. 32(1), 293-296 (2012) 369. Wang Chen，Wu Jie，Zong Chen，Xu Jie，Huangxian Ju*, 化学发光免疫分析方法与应用进展, 分析化学, 40, 3-10 (2012). Chemiluminescent immunoassay and its applications, Chin. J. Anal. Chem. 40(1), 3-10 (2012) 370. Jianping Lei, Huangxian Ju*, Signal amplification using functional nanomaterials for biosensing, Chem. Soc. Rev. 41, 2122-2134 (2012) 371. En Han, Lin Ding, Ruocan Qian, Lei Bao, Huangxian Ju*, Sensitive chemiluminescent imaging for chemoselective analysis of glycan expression on living cells using a multifunctional nanoprobe, Anal. Chem. 84(3), 1452–1458 (2012) 372. Haifeng Dong, Zhu Zhu, Huangxian Ju*, Feng Yan*, Triplex signal amplification for electrochemical DNA biosensing by coupling probe-gold nanoparticles-graphene modified electrode with enzyme functionalized carbon sphere as tracer, Biosens. Bioelectron. 33, 228-232 (2012) 373. Guosong Lai, Lili Wang, Jie Wu, Huangxian Ju*, Feng Yan*, Electrochemical stripping analysis of nanogold label-induced silver deposition for ultrasensitive multiplexed detection of tumor markers, Anal. Chim. Acta 721, 1-6 (2012) featured article and cover paper 374. Qing Li, Wei Cheng, Decai Zhang, Tianxiao Yu, Yibin Yin, Huangxian Ju, Shijia Ding*, Rapid and sensitive strategy for salmonella detection using an InvA gene-based electrochemical DNA sensor, Int. J. Electrochem. Sci. 7, 844-856 (2012)

375. Patoommarn Wipawakarn, Huangxian Ju, Danny K. Y. Wong*, A label-free electrochemical DNA biosensor based on a Zr(IV)-coordinated DNA duplex immobilized on a carbon nanofibre/chitosan layer, Anal. Bioanal. Chem. 402, 2817-2826 (2012) 376. Chen Zong, Jie Wu, Chen Wang, Huangxian Ju*, Feng Yan*, Chemiluminescence imaging immunoassay of multiple tumor markers for cancer screening, Anal. Chem. 84(5), 2410–2415 (2012) 377. Ruocan Qian, Lin Ding, Lei Bao, Shujun He, Huangxian Ju*, In situ electrochemical assay of cell surface sialic acids featuring highly efficient chemoselective recognition and a dual-functionalized nanohorn probe, Chem. Commun. 48, 3848-3850(2012) 378. Qiunan Xu, Feng Yan, Jianping Lei*, Chuan Leng, Huangxian Ju*, Disposable electrochemical immunosensor by using carbon sphere/gold nanoparticle composites as labels for signal amplification, Chem. Eur. J. 18, 4994– 4998 (2012), as a VIP and cover paper 379. Jin Sheng, Ping Qu, Jianping Lei, Huangxian Ju*, Chaojin Song, Daming Zhang, Fast and high-performance screening of narcotic drugs on a microfluidic device by micellar electrokinetic capillary chromatography, Anal. Lett. 45(7), 652-664 (2012) 380. Haifeng Dong, Jianping Lei, Huangxian Ju*, Feng Zhi, Hua Wang, Wenjie Guo, Zhu Zhu, Feng Yan*, Target- cell-specific delivery, imaging, and detection of intracellular microRNA with a multifunctional SnO2 nanoprobe, Angew. Chem. Int. Ed. 51, 4607–4612 (2012) 381. Dajie Lin, Jie Wu, Min Wang, Feng Yan, Huangxian Ju*, Triple signal amplification of graphene film, polybead carried gold nanoparticles as tracing tag and silver deposition for ultrasensitive electrochemical immunosensing, Anal. Chem. 84(8), 3662–3668 (2012) 382. Caihui Luo, Yaning Lei, Li Yan, Tianxiao Yu, Qing Li, Decai Zhang, Shijia Ding*, Huangxian Ju*, A rapid and sensitive aptamer-based electrochemical biosensor for direct detection of Escherichia coli O111, Electroanalysis 24(5), 1186–1191 (2012) 383. Lei Zhang, Jianping Lei*, Jing Zhang, Lin Ding, Huangxian Ju, Amperometric detection of hypoxanthine and xanthine by enzymatic amplification using a gold nanoparticles-carbon nanohorn hybrid as the carrier, Analyst 137 (13), 3126–3131 (2012) 384. Wenwen Tu, Wenjing Wang, Jianping Lei,* Shengyuan Deng, Huangxian Ju*, Chemiluminescence excited photoelectrochemistry using graphene-quantum dots nanocomposite for biosensing, Chem. Commun. 48(52), 6535–6537 (2012) 385. Haifeng Dong, Jing Zhang, Huangxian Ju*, Huiting Lu, Shiyan Wang, Shi Jin, Kaihong Hao, Hongwu Du, Xueji Zhang*, Highly sensitive multiple microRNA detection based on fluorescence quenching of graphene oxide and isothermal strand-displacement polymerase reaction, Anal. Chem. 84, 4587–4593 (2012) 386 Tianxiao Yu, Wei Cheng, Qing Li, Caihui Luo, Li Yan, Decai Zhang, Yibing Yin, Shijia Ding*, Huangxian Ju*, Electrochemical immunosensor for competitive detection of neuron specific enolase using functional carbon nanotubes and gold nanoprobe, Talanta 93, 433-438 (2012) 387. Wei Cheng, Shijia Ding, Qing Li, Tianxiao Yu, Yibin Yin, Huangxian Ju*, Guosheng Ren*, A simple electrochemical aptasensor for ultrasensitive protein detection using cyclic target-induced primer extension, Biosens. Bioelectron. 36, 12-17 (2012) 388. Qing Hao, Peng Wang, Xiuyuan Ma, Mengqi Su, Jianping Lei*, Huangxian Ju*, Charge recombination suppression-based photoelectrochemical strategy for detection of dopamine, Electrochem. Commun. 21, 39- 41 (2012) 389. Hanxu Ji, Feng Yan, Jianping Lei, Huangxian Ju*, Ultrasensitive electrochemical detection of nucleic acids by template enhanced hybridization followed with rolling circle amplification, Anal. Chem. 84(16), 7166– 7171(2012) 390. Decai Zhang, Yurong Yan, Qing Li, Tianxiao Yu, Wei Cheng, Long Wang, Huangxian Ju, Shijia Ding*, Label- free and high-sensitive detection of Salmonella using a surface plasmon resonance DNA-based biosensor, J. Biotechnol. 160(3-4), 123-128 (2012) 391. Yu T. X., Li J. B., Liu Q. F., Cheng W., Zhang D. C., Ju H. X., Ding S. J., Electrochemical aptasensor based on Klenow fragment polymerase reaction for ultrasensitive detection of PDGF-BB，Int. J. Electrochem. Sci. 7(9), 8533-8542(2012) 392. Wenjing Wang, Lei Bao, Jianping Lei*, Wenwen Tu, Huangxian Ju*, Visible light induced photoelectrochemical biosensing based on oxygen-sensitive quantum dots, Anal. Chim. Acta 744, 33-38(2012) 393. Zhihui Dai, Huangxian Ju*, Bioanalysis based on nanoporous materials, TrAC Trends Anal. Chem. 39, 149- 162 (2012) 394. Lisong Wang, Chuan Leng, Sheng Tang, Jianping Lei*, Huangxian Ju*, Enzyme-free signal amplification for

electrochemical detection of Mycobacterium lipoarabinomannan antibody on a disposable chip, Biosens. Bioelectron. 38(1), 421-424(2012) 395. Zhu Zhu, Fenglei Gao, Jianping Lei, Haifeng Dong, Huangxian Ju*, A competitive strategy coupled with endonuclease-assistant target recycling for DNA detection using silver-nanoparticles-tagged carbon nanospheres as labels, Chem. Eur. J. 18, 13871-13876 (2012) 396. Jie Li, Jianping Lei*, Quanbo Wang, Peng Wang, Huangxian Ju*, Bionic catalysis of porphyrin for electrochemical detection of nucleic acids, Electrochim. Acta 83, 73-77 (2012) 397. Shengyuan Deng, Jianping Lei, Yin Huang, Xiaonan Yao, Lin Ding, Huangxian Ju*, Electrocatalytic reduction of coreactant by highly loaded dendrimer-encapsulated palladium nanoparticles for sensitive electrochemiluminescent immunoassay, Chem. Commun. 48 (73), 9159-9161(2012) 398. Fenglei Gao, Zhu Zhu, Jianping Lei, Huangxian Ju*, Raman spectroscopic detection of sub-picomolar DNA by coupling silver catalyzed silver deposition with circular strand-replacement polymerization on magnetic nanoparticles, Chem. Commun. 48 (86), 10603 – 10605 (2012) inside cover paper 399. Lei Zhang, Ping Qu, Jin Sheng, Jianping Lei*, Huangxian Ju*, Open tubular microreactor with enzyme functionalized microfluidic channel for amperometric detection of glucose, Chinese J. Chem. 30(9), 2145-2150 (2012) 400. Peng Wang, Xiuyuan Ma, Mengqi Su, Qing Hao, Jianping Lei*, Huangxian Ju*, Cathode photoelectrochemical sensing of copper (II) based on analyte-induced formation of exciton trapping, Chem. Commun. 48, 10216- 10218 (2012) 401. Huangxian Ju, Signal amplification for highly sensitive bioanalysis based on biosensors or biochips, an editorial article, J. Biochips Tiss Chips 2(3), 1000e114 (2012) 402. Haifeng Dong, Shi Jin, Huangxian Ju, Kaihong Hao, Li-Ping Xu, Huiting Lu, and Xueji Zhang*，Trace and label- free microRNA detection using oligonucleotide encapsulated silver nanoclusters as probes, Anal. Chem. 84(20), 8670–8674 (2012) 403. Yin Ding*, Huangxian Ju, Yuhua Zhu, Research on construction and management of large-scale instruments platform of state key laboratory, Experimental Technology and Management, 国家重点实验室大型仪器平台的建设与管理研究, 实验技术与管理 29(11), 210-212, 216 (2012) 2013 41 papers 404. Fenglei Gao, Zhu Zhu, Jianping Lei, Yao Geng, Huangxian Ju*, Sub-femtomolar electrochemical detection of DNA using surface circular strand-replacement polymerization and gold nanoparticle catalyzed silver deposition for signal amplification, Biosens. Bioelectron. 39, 199-203 (2013) 405. Shengyuan Deng, Huangxian Ju*, Electrogenerated chemiluminescence of nanomaterials for bioanalysis, Analyst 138 (1), 43 -61 (2013) 406. Haifeng Dong, Chen Wang, Yi Xiong, Huiting Lu, Huangxian Ju*, Xueji Zhang*, Highly sensitive and selective chemiluminescent imaging for DNA detection by ligation-mediated rolling circle amplified synthesis of DNAzyme, Biosens. Bioelectron. 41, 348-353 (2013) 407. Shengyuan Deng, Jianping Lei, Xiaonan Yao, Yin Huang, Dajie Lin, Huangxian Ju*, Synthesis and low-potential electrogenerated chemiluminescence of surface passivated phenol formaldehyde resin@CdS quantum dots, J. Mater. Chem. C 1, 299-306 (2013) 408. Yunlong Chen, Lin Ding*, Huangxian Ju*, In situ tracing of cell surface sialic acid by chemoselective recognition to unload gold nanocluster probe from density tunable dendrimeric array, Chem. Commun. 49(9), 862-864 (2013) inside cover paper 409. Quanbo Wang, Jianping Lei*, Shengyuan Deng, Lei Zhang, Huangxian Ju*, Graphene-supported ferric porphyrin as a peroxidase mimic for electrochemical DNA biosensing, Chem. Commun. 49(9), 916-918(2013) 410. Rongna Ma, Minghua Lu, Lin Ding, Huangxian Ju*, Zongwei Cai*, Surface-assisted laser desorption/ionization mass spectrometric detection of biomolecules by using functional single-walled carbon nanohorns as the matrix, Chem. Eur. J. 19, 102-108 (2013) as a VIP and frontispiece 411. Yao Geng, Yanfang Gao, Huangxian Ju*, Feng Yan*, Diagnostic and prognostic value of plasma and tissue ubiquitin-like, containing PHD and RING finger domains 1 in breast cancer patients, Cancer Sci. 104, 194-199 (2013) 412. Jin Zhang, Jianping Lei, Huangxian Ju*, Chaoying Wang, Yanhui Niu, An amperometric sensor for picloram based on its imprinting in composite membrane of o-aminothiophenol and Au nanoparticles, Scientia Sinica Chimica, 毒莠定印迹邻氨基苯硫酚/金纳米粒子复合膜安培传感器, 中国科学：化学 43(5), 585-591 (2013) 413. Changrong Zhao, Dajie Lin, Jie Wu, Lin Ding, Huangxian Ju*, Feng Yan*, Nanogold-enriched carbon nanohorn label for sensitive electrochemical detection of biomarker on a disposable immunosensor, Electroanalysis 25,

1044-1049 (2013), the Special Issue for the 80th birthday of Prof Erkang Wang 414. Chen Zong, Jie Wu, Jie Xu, Huangxian Ju*, Feng Yan*, Multilayer hemin/G-quadruplex wrapped gold nanoparticles as tag for ultrasensitive multiplex immunoassay by chemiluminescence imaging, Biosens. Bioelectron. 43, 372-378 (2013) 415. Shengyuan Deng, Jianping Lei, Ye Liu, Yin Huang, Huangxian Ju*, A ferrocenyl-terminated dendrimer as an efficient quencher via electron and energy transfer for cathodic electrochemiluminescent bioanalysis, Chem. Commun. 49(21), 2106-2108 (2013) inside cover paper 416. Decai Zhang, Yurong Yan, Wei Cheng, Wei Zhang, Yahui Li, Huangxian Ju, Shijia Ding*, Streptavidin-enhanced surface plasmon resonance biosensor for highly sensitive and specific detection of microRNA, Microchim. Acta 180(5-6), 397-403 (2013) 417. Dajie Lin, Jie Wu, Huangxian Ju*, Feng Yan*, Signal amplification for electrochemical immunosensing by in situ assembly of host-guest linked gold nanorod superstructure on immunocomplex, Biosens. Bioelectron. 45, 195- 200 (2013) 418. Jie Xu, Jie Wu*, Chen Zong, Huangxian Ju*, Feng Yan, Manganese porphyrin-dsDNA complex: A mimicking enzyme for highly efficient bioanalysis, Anal. Chem. 85(6), 3374-3379 (2013) 419. Fenglei Gao, Jianping Lei, Huangxian Ju*, Assistant DNA recycling with nicking endonuclease and molecular beacon for signal amplification using a target-complementary arched structure, Chem. Commun. 49, 4006-4008 (2013) 420. Huangxian Ju*, Grand challenges in analytical chemistry: Towards more bright eyes for scientific research, social events and human health, Fronti. Chem. 1, 5 (2013) 10.3389/fchem.2013.00005, published: 26 Mar 2013 421. Feng Zhi, Haifeng Dong, Xuefeng Jia, Wenjie Guo, Huiting Lu, Yilin Yang, Huangxian Ju*, Xueji Zhang*, Yiqiao Hu*, Functionalized graphene oxide mediated adriamycin delivery and miR-21 gene silencing to overcome tumor multidrug resistance in vitro, Plos One 8(3), e60034 (2013) 422. Shengyuan Deng, Lingxiao Cheng, Jianping Lei, Yan Cheng, Yin Huang, Huangxian Ju*, Label-free electrochemiluminescent detection of DNA by hybridization with a molecular beacon to form hemin/G-quadruplex architecture for signal inhibition, Nanoscale 5, 5435-5441 (2013) 423. Haifeng Dong, Jianping Lei, Lin Ding, Yongqiang Wen, Huangxian Ju*, Xueji Zhang*, MicroRNA: Function, detection, and bioanalysis, Chem. Rev. 113(8), 6207-6233 (2013) 424. Yao Geng, Dajie Lin, Lijia Shao, Feng Yan*, Huangxian Ju*, Cellular delivery of quantum dot-bound hybridization probe for detection of intracellular pre-microRNA using chitosan/poly(γ-glutamic acid) complex as a carrier, Plos One 8(6), e65540 (2013) dx.plos.org/10.1371/journal.pone.0065540 425. Shengyuan Deng, Jianping Lei, Yin Huang, Yan Cheng, Huangxian Ju*, Electrochemiluminescent quenching of quantum dots for ultrasensitive immunoassay through oxygen reduction catalyzed by nitrogen-doped graphene- supported hemin, Anal. Chem. 85(11), 5390-5396 (2013) 426. Caihui Luo, Hua Tang, Wei Cheng, Li Yan, Decai Zhang, Huangxian Ju, Shijia Ding*, A sensitive electrochemical DNA biosensor for specific detection of Enterobacteriaceae bacteria by exonuclease III-assisted signal amplification, Biosens. Bioelectron. 48, 132-137 (2013) 427. Jin Zhang, Jianping Lei, Huangxian Ju*, Chaoying Wang, Electrochemical sensor based on chlorohemin modified molecularly imprinted microgel for determination of 2,4-dichlorophenol, Anal. Chim. Acta 786, 16-21 (2013) 428. Fenglei Gao, Jianping Lei, Huangxian Ju*, Sensitive fluorescence detection of DNA using isothermal exponential amplification coupled quantum dots coated silica nanospheres as label, RSC Advances 3, 13163-13168 (2013) 429. Lisong Wang, Jianping Lei*, Rongna Ma, Huangxian Ju*, Host-guest interaction of adamantine with a β- cyclodextrin-functionalized AuPd bimetallic nanoprobe for ultrasensitive electrochemical immunoassay of small molecules, Anal. Chem. 85(13), 6505-6510 (2013) 430. Liu Tong, Jie Wu*, Jie Li, Huangxian Ju*, Feng Yan, Hybridization chain reaction engineered DNA nanopolylinker for amplified electrochemical sensing of biomarkers, Analyst 138(17), 4870-4876 (2013) 431. Fenglei Gao, Jianping Lei, Huangxian Ju*, Ultrasensitive fluorescence detection of bleomycin via exonuclease III- aided DNA recycling amplification, Chem. Commun. 49(68), 7561-7563 (2013) 432. Lin Liu, Jianping Lei*, Fenglei Gao, Huangxian Ju, A DNA machine for sensitive and homogeneous DNA detection via lambda exonuclease assisted amplification, Talanta 115, 819-822 (2013) 433. Lei Zhang, Yan Cheng, Jianping Lei*, Yueting Liu, Qing Hao, Huangxian Ju, Stepwise chemical reaction strategy for highly sensitive electrochemiluminescent detection of dopamine, Anal. Chem. 85(16), 8001-8007 (2013) 434. Peng Wang, Jianping Lei, Mengqi Su, Yueting Liu, Qing Hao, Huangxian Ju*, Highly efficient visual detection of trace copper(II) and protein by the quantum photoelectric effect, Anal. Chem. 85(18), 8735-8740 (2013) 435. Ruocan Qian, Lin Ding, Huangxian Ju*, Switchable fluorescent imaging of intracellular telomerase activity using telomerase-responsive mesoporous silica nanoparticle, J. Am. Chem. Soc. 135(36), 13282-13285 (2013)

436. Zhu Zhu, Jianping Lei, Lin Liu, Huangxian Ju*, Label-free electrochemical DNA sensing with a one-target- multitriggered hybridization chain reaction strategy, Analyst 138, 5995-6000 (2013) 437. Qiunan Xu, Lisong Wang, Jianping Lei*, Shengyuan Deng, Huangxian Ju*, Platinum nanodendrite functionalized graphene nanosheets as a non-enzymatic label for electrochemical immunosensing, J. Mater. Chem. B 1, 5347- 5352 (2013) 438. Yunlong Chen, Lin Ding, Tingting Liu, Huangxian Ju*, Arrayed profiling of multiple glycans on whole living cell surfaces, Anal. Chem. 85(22), 11153–11158 (2013) 439. Lei Zhang, Jianping Lei*, Lin Liu, Changfeng Li, Huangxian Ju, Self-assembled DNA hydrogel as switchable material for aptamer-based fluorescent detection of protein, Anal. Chem. 85(22), 11077-11082 (2013) 440. Fenglei Gao, Jianping Lei, Huangxian Ju*, Label-free surface-enhanced raman spectroscopy for sensitive DNA detection by DNA-mediated silver nanoparticle growth, Anal. Chem. 85(24), 11788-11793 (2013) 441. Quanbo Wang, Wei Wang, Jianping Lei, Nan Xu, Fenglei Gao, Huangxian Ju*，Fluorescence quenching of carbon nitride nanosheet through its interaction with DNA for versatile fluorescence sensing, Anal. Chem. 85(24), 12182-12188 (2013) 442. Jiangwei Tian, Lin Ding, Hai-Jun Xu, Zhen Shen, Huangxian Ju*, Li Jia, Lei Bao, Junsheng Yu*, Cell-specific and pH-activatable rubyrin-loaded nanoparticles for highly selective near-infrared photodynamic therapy against cancer, J. Am. Chem. Soc. 135(50), 18850-18858 (2013) 443. Yin Ding*, Yuhua Zhu, Jie Pang, Huangxian Ju, Exploration and practice on cultural construction of state key laboratory, Experimental Technology and Management, 国家重点实验室文化建设的探索与实践, 实验技术与管理 30(5), 181-184 (2013) 444. Xuelian Mao, Mingchen Zhu, Yao Geng, Jianwei Xu, Huangxian Ju, Feng Yan*, Correlation of ER, PR, C-erbB- 2, CD44V6 and Ki67 expression in breast cancer and their clinical significance, Prog. Modern Biomed., 乳腺癌组织中ER、PR、C-erbB-2、CD44V6、Ki67表达的相关分析及临床意义, 现代生物医学进展 13(35), 6822-6825 (2013) 2014 39 papers 445. Zhanjun Yang*, Jing Zhu, Hua Dai, Juan Li, Juan Shen, Xinan Jiao, Xiaoya Hu, Huangxian Ju*, Graphene oxide based ultrasensitive flow-through chemiluminescent immunoassay for sub-picogram level detection of chicken interferon-γ, Biosens. Bioelectron. 51, 356-361 (2014) 446. Yan Cheng, Jianping Lei*, Yunlong Chen, Huangxian Ju, Highly selective detection of microRNA based on distance-dependent electrochemiluminescence resonance energy transfer between CdTe nanocrystals and Au nanoclusters, Biosens. Bioelectron. 51, 431-436 (2014) 447. Dajie Lin, Jie Wu, Huangxian Ju*, Feng Yan*, Nanogold/mesoporous carbon foam-mediated silver enhancement for graphene-enhanced electrochemical immunosensing of carcinoembryonic antigen, Biosens. Bioelectron., 52, 153-158 (2014) 448. Rongna Ma, Junjie Hu, Zongwei Cai, Huangxian Ju*, Highly selective enrichment of phosphopeptides with high- index facets exposed octahedral tin dioxide nanoparticles for mass spectrometric analysis, Talanta 119, 452-457 (2014) 449. Jie Qin*, Sheng-Yuan Deng, Chen-Xi Qian, Tian-Yi Li, Huang-Xian Ju, Jing-Lin Zuo, Ionic iridium complex coordinated with tetrathiafulvalene-fused phenanthroline ligand: Synthesis, photophysical, electrochemical and electrochemiluminescence properties, J. Organomet. Chem. 750, 7-12 (2014) 450. Zhentao Cui, Dan Wu, Yong Zhang, Hongmin Ma, He Li, Bin Du, Qin Wei*, Huangxian Ju*, Ultrasensitive electrochemical immunosensors for multiplexed determination using mesoporous platinum nanoparticles as nonenzymatic labels, Anal. Chim. Acta 807, 44-50 (2014) 451. Lin Cui, Jie Wu, Jie Li, Yanqiu Ge, Huangxian Ju*, Electrochemical detection of Cu2+ through Ag nanoparticle assembly regulated by copper-catalyzed oxidation of cysteamine, Biosens. Bioelectron. 55, 272-277 (2014) 452. Yanqiu Ge, Jie Wu*, Huangxian Ju, Shuo Wu*, Ultrasensitive enzyme-free electrochemical immunosensor based on hybridization chain reaction triggered double strand DNA@Au nanoparticle tag, Talanta 120, 218-223 (2014) 453. Wenjing Wang, Qing Hao, Wei Wang, Lei Bao, Jianping Lei*, Quanbo Wang, Huangxian Ju, Quantum dot- functionalized porous ZnO nanosheets as a visible light induced photoelectrochemical platform for DNA detection, Nanoscale 6, 2710-2717 (2014) 454. Rongna Ma, Junjie Hu, Zongwei Cai, Huangxian Ju*, Facile synthesis of boronic acid-functionalized magnetic carbon nanotubes for highly specific enrichment of glycopeptides, Nanoscale 6, 3150-3156 (2014) 455. Yueting Liu, Quanbo Wang, Jianping Lei, Qing Hao, Wei Wang, Huangxian Ju*, Anodic electrochemiluminescence of graphitic-phase C3N4 nanosheets for sensitive biosensing, Talanta 122, 130-134 (2014)

456. Kewei Ren, Jie Wu, Feng Yan, Huangxian Ju*, Ratiometric electrochemical proximity assay for sensitive one- step protein detection, Sci. Rep. 4, 4360 (2014), DOI:10.1038/srep04360 457. Ruijie Yu, Jiaxi Song, Jia Wu, Dongmei Niu, Lijuan Ma, Chen Zong, Huangxian Ju*, Junjun Wang*, A sensitive chemiluminescence imaging immunoassay for simultaneous detection of serum oxidized lipoprotein (a) and low density lipoprotein, Clin. Chem. Lab. Med. 52, 869-877 (2014) 458. Rong Luo, Yahui Li, Xiaojuan Lin, Fang Dong, Wei Zhang, Li Yan, Wei Cheng, Huangxian Ju, Shijia Ding*, A colorimetric assay method for invA gene of Salmonella using DNAzyme probe self-assembled gold nanoparticles as single tag, Sens. Actuat. B 198, 87-93 (2014) 459. Jianping Lei, Ruocan Qian, Pinghua Ling, Lin Cui, Huangxian Ju*, Design and sensing applications of metal- organic framework composites, TrAC Trends Anal. Chem. 58, 71-78 (2014) 460. Xiaoping Yu, Yana Li, Jie Wu*, Huangxian Ju, Motor-based autonomous microsensor for motion and counting immunoassay of cancer biomarker, Anal. Chem. 86, 4501-4507 (2014) 461. Yan Cheng, Yin Huang, Jianping Lei*, Lei Zhang, Huangxian Ju, Design and biosensing of Mg2+-dependent DNAzyme-triggered ratiometric electrochemiluminescence, Anal. Chem. 86(10), 5158-5163 (2014) 462. Quanbo Wang, Nan Xu, Jianping Lei, Huangxian Ju*, Regulative peroxidase activity of DNA-linked hemin by graphene oxide for fluorescence DNA sensing, Chem. Commun. 50(51), 6714-6717 (2014) 463. Zhaogang Teng, Shouju Wang, Xiaodan Su, Guotao Chen, Ying Liu, Zhimin Luo, Wei Luo, Yuxia Tang, Huangxian Ju, Dongyuan Zhao, Guangming Lu*, Facile synthesis of yolk–shell structured inorganic–organic hybrid spheres with ordered radial mesochannels, Adv. Mater. 26(22), 3741-3747 (2014) 464. Chen Zong, Jie Wu, Mengmeng Liu, Linlin Yang, Lin Liu, Feng Yan, Huangxian Ju*, Proximity hybridization- triggered signal switch for homogeneous chemiluminescent bioanalysis, Anal. Chem. 86(11), 5573-5578 (2014) 465. Ruocan Qian, Lin Ding, Liwen Yan, Manfei Lin, Huangxian Ju*, A robust probe for lighting up intracellular telomerase via primer extension to open a nicked molecular beacon, J. Am. Chem. Soc. 136(23), 8205-8208 (2014) 466. Yao Geng, Jie Wu, Lijia Shao, Feng Yan*, Huangxian Ju*, Sensitive colorimetric biosensing for methylation analysis of p16/CDKN2 promoter with hyperbranched rolling circle ampliﬁcation, Biosens. Bioelectron. 61, 593-597 (2014) 467. Jiangwei Tian, Lin Ding, Huangxian Ju*, Yongchao Yang, Xilan Li, Zhen Shen, Zhi Zhu, Junsheng Yu*, Chaoyong James Yang*, A multifunctional nanomicelle for real-time targeted imaging and precise near-infrared cancer therapy, Angew. Chem. Int. Ed. 53(36), 9544-9549 (2014) 468. Junjie Hu, Rongna Ma, Fei Liu, Yunlong Chen, Huangxian Ju*, Mercaptophenylboronic acid modified gold nanoparticle@silica bubbles for buoyant separation and specific enrichment of glycopeptides, RSC Advances 4(55), 28856-28859 (2014) 469. Kewei Ren, Jie Wu, Yue Zhang, Feng Yan, Huangxian Ju*, Proximity hybridization regulated DNA biogate for sensitive electrochemical immunoassay, Anal. Chem. 86(15), 7494-7499 (2014) 470. Dan Zhu, Yurong Yan, Pinhua Lei, Bo Shen, Wei Cheng, Huangxian Ju, Shijia Ding*, A novel electrochemical sensing strategy for rapid and ultrasensitive detection of Salmonella by rolling circle amplification and DNA- AuNPs probe, Anal. Chim. Acta 846, 44-50 (2014) 471. Rongna Ma, Junjie Hu, Zongwei Cai, Huangxian Ju*, Dual quinone tagging for MALDI-TOF mass spectrometric quantitation of cysteine-containing peptide, Anal. Chem. 86(16), 8275-8280 (2014) 472. Yueting Liu, Jianping Lei, Yin Huang, Huangxian Ju*, “Off-on” electrochemiluminescence system for sensitive detection of ATP via target-induced structure switching, Anal. Chem. 86(17), 8735-8741 (2014) 473. Ruocan Qian, Lin Ding, Liwen Yan, Manfei Lin, Huangxian Ju*, Smart vesicle kit for in situ monitoring of intracellular telomerase activity using a telomerase-responsive probe, Anal. Chem. 86(17), 8642-8648 (2014) 474. Changrong Zhao, Jie Wu, Huangxian Ju*, Feng Yan*, Multiplexed electrochemical immunoassay using streptavidin/nanogold/carbon nanohorn as a signal tag to induce silver deposition, Anal. Chim. Acta 847, 37-43 (2014) 475. Xiaoping Yu, Jie Wu*, Huangxian Ju, The application of micro/nanomotor in biosensing, Chem. Prog. 微/纳米马达在生物传感中的应用, 化学进展 26(10), 1712-1719 (2014) 476. Yang Zang, Jianping Lei*, Qing Hao, Huangxian Ju, “Signal-on” photoelectrochemical sensing strategy based on target-dependent aptamer conformational conversion for selective detection of lead (II) ion, ACS Applied Mater. Interf. 6(18), 15991-15997 (2014) 477. Chen Zong, Jie Wu, Mengmeng Liu, Linlin Yang, Feng Yan, Huangxian Ju*, Chemiluminescence imaging for a protein assay via proximity-dependent DNAzyme formation, Anal. Chem. 86 (19), 9939-9944 (2014) 478. Lin Cui, Jie Wu, Huangxian Ju*, Nitrogen-doped porous carbon derived from metal-organic gel for

electrochemical analysis of heavy-metal ion, ACS Applied Mater. Interf. 6(18), 16210-16216 (2014) 479. Xianjiu Liao, Quanbo Wang, Huangxian Ju*, Simultaneous sensing of intracellular microRNAs with a multi- functionalized carbon nitride nanosheet probe, Chem. Commun. 50(88), 13604-13607 (2014) 480. Lin Liu, Qianhui Yang, Jianping Lei*, Nan Xu, Huangxian Ju, DNA-regulated silver nanoclusters for label-free ratiometric fluorescence detection of DNA, Chem. Commun. 50(88), 13698-13701 (2014) 481. Quanbo Wang, Nan Xu, Zhen Gui, Jianping Lei, Huangxian Ju*, Feng Yan*, Catalytic activity of a dual-hemin labelled oligonucleotide: Conformational dependence and fluorescent DNA sensing, Chem. Commun. 50(97), 15362-15365 (2014) 482. Yang Zang, Jianping Lei*, Lei Zhang, Huangxian Ju, In situ generation of electron acceptor for photoelectrochemical biosensing via hemin-mediated catalytic reaction, Anal. Chem. 86(24), 12362-12368 (2014) 2015 43 papers 483. Lin Cui, Jie Wu, Huangxian Ju*, Electrochemical sensing of heavy metal ions with inorganic, organic and biomaterials, Biosens. Bioelectron. 63, 276-286 (2015) 484. Changfeng Li, Jianxia Feng, Huangxian Ju*, Supramolecular interaction of labetalol with cucurbit[7]uril for its sensitive fluorescence detection, Analyst 140 (1), 230-235 (2015) 485. Nan Xu, Quanbo Wang, Jianping Lei*, Lin Liu, Huangxian Ju, Label-free triple-helix aptamer as sensing platform for "signal-on" fluorescent detection of thrombin, Talanta 132, 387–391 (2015) 486. Guangming Wen, Huangxian Ju*, Ultrasensitive photoelectrochemical immunoassay through tag induced exciton trapping, Talanta 134, 496–500 (2015) 487. Kewei Ren, Jie Wu, Feng Yan, Yue Zhang, Huangxian Ju*, Immunoreaction-triggered DNA assembly for one- step sensitive ratiometric electrochemical biosensing of protein biomarker, Biosens. Bioelectron. 66, 345-349 (2015) 488. Xianjiu Liao, Huangxian Ju*, In situ quantitation of intracellular microRNA in the whole cell cycle with a functionalized carbon nanosphere probe, Chem. Commun. 51, 2141-2144 (2015) 489. Bo Shen, Jianbo Li, Wei Cheng, Yurong Yan, Renkuan Tang, Yongguo Li, Huangxian Ju, Shijia Ding*, Electrochemical aptasensor for highly sensitive determination of cocaine using a supramolecular aptamer and rolling circle amplification, Microchim. Acta 182, 361-367 (2015) 490. Yin Huang, Jianping Lei*, Yan Cheng, Huangxian Ju, Target-assistant Zn2+-dependent DNAzyme for signal-on electrochemiluminescent biosensing, Electrochim. Acta 155, 341-347 (2015) 491. Kewei Ren, Jie Wu, Huangxian Ju*, Feng Yan*, Target-driven triple-binder assembly of MNAzyme for amplified electrochemical immunosensing of protein biomarker, Anal. Chem. 87(3), 1694-1700 (2015) 492. Pinghua Ling, Qing Hao, Jianping Lei*, Huangxian Ju, Porphyrin functionalized porous carbon derived from metal- organic framework as a biomimetic catalyst for electrochemical biosensing, J. Mater. Chem. B 3, 1335-1341 (2015) 493. Chen Zong, Jie Wu, Mengmeng Liu, Feng Yan, Huangxian Ju*, High-throughput imaging assay of multiple proteins via target-induced DNA assembly and cleavage, Chem. Sci. 6, 2602-2607 (2015) 494. Chenyang Tao, Yurong Yan, Hua Xiang, Dan Zhu, Wei Cheng, Huangxian Ju, Shijia Ding*, A new mode for highly sensitive and specific detection of DNA based on exonuclease III-assisted target recycling amplification and mismatched catalytic hairpin assembly, Chem. Commun. 51, 4220-4222 (2015) 495. Yana Li, Jie Wu*, Yuzhe Xie, Huangxian Ju, An efficient polymeric micromotor doped with Pt nanoparticle@carbon nanotubes for complex bio-media, Chem. Commun. 51, 6325-6328 (2015) 496. Jiangwei Tian, Lin Ding, Quanbo Wang, Yaoping Hu, Li Jia, Jun-Sheng Yu, Huangxian Ju*, Folate receptor- targeted and cathepsin B-activatable nanoprobe for in situ therapeutic monitoring of photosensitive cell death, Anal. Chem. 87, 3841-3848 (2015) 497. Pinghua Ling, Jianping Lei*, Lei Zhang, Huangxian Ju, Porphyrin-encapsulated metal-organic frameworks as mimetic catalysts for electrochemical DNA sensing via allosteric switch of hairpin DNA, Anal. Chem. 87, 3957- 3963 (2015) 498. Ye Zhang, Yurong Yan, Wenhong Chen, Wei Cheng, Shengqiang Li, Xiaojuan Ding, Dandan Li, Hong Wang, Huangxian Ju, Shijia Ding*, A simple electrochemical biosensor for highly sensitive and specific detection of microRNA based on mismatched catalytic hairpin assembly, Biosens. Bioelectron. 68, 343-349 (2015) 499. Shouju Wang, Zhaogang Teng, Peng Huang, Dingbin Liu, Ying Liu, Ying Tian, Jing Sun, Yanjun Li, Huangxian Ju, Xiaoyuan Chen, Guangming Lu*, Reversibly extracellular pH controlled cellular uptake and photothermal therapy by PEGylated mixed-charge gold nanostars, Small 11(15), 1801-1810 (2015) (inside front cover) 500. Guangming Wen, Peng Wang, Wenwen Tu, Janping Lei, Huangxian Ju*, Biosensing strategy based on photocurrent quenching of quantum dots via energy resonance absorption, Sci. China Chem. 58 (5), 879-884

(2015) (hot paper) 501. Junjie Hu, Fei Liu, Huangxian Ju*, Peptide code-on-a-microplate for protease activity analysis via MALDI-TOF mass spectrometric quantitation, Anal. Chem. 87(8), 4409-4414 (2015) 502. Lei Zhang, Jianping Lei*, Jintong Liu, Fengjiao Ma, Huangxian Ju*, In situ activation and monitoring of the evolution of the intracellular caspase family, Chem. Sci. 6, 3365-3372 (2015) 503. Pinghua Ling, Jianping Lei*, Huangxian Ju, Porphyrinic metal-organic framework as electrochemical probe for DNA sensing via triple-helix molecular switch, Biosens. Bioelectron. 71, 373-379 (2015) 504. Yang Zang, Jianping Lei*, Pinghua Ling, Huangxian Ju, Catalytic hairpin assembly-programmed porphyrin-DNA complex as photoelectrochemical initiator for DNA biosensing, Anal. Chem. 87(10), 5430-5436 (2015) 505. Xianjiu Liao, Quanbo Wang, Huangxian Ju*, A peptide nucleic acid-functionalized carbon nitride nanosheet as a probe for in situ monitoring of intracellular microRNA, Analyst 140, 4245-4252(2015) 506. Yunlong Chen, Lin Ding, Junqiang Xu, Wanyao Song, Min Yang, Junjie Hu, Huangxian Ju*, Micro-competition system for Raman quantification of multiple glycans on intact cell surface, Chem. Sci. 6, 3769-3774 (2015) 507. Yuehua Guo, Jie Wu, Huangxian Ju*, Target-driven DNA association to initiate cyclic assembly of hairpins for biosensing and logic gate operation, Chem. Sci. 6, 4318-4323 (2015) 508. Lei Bao, Lin Ding, Min Yang, Huangxian Ju*, Noninvasive imaging of sialyltransferase activity in living cells by chemoselective recognition, Sci. Rep. 5, 10947 (2015) 509. Haifeng Dong*, Wenhao Dai, Huangxian Ju, Huiting Lu, Shiyan Wang, Liping Xu, Shu-Feng Zhou, Yue Zhang*, Xueji Zhang*, Multifunctional poly(L-lactide)-polyethylene glycol-grafted graphene quantum dots for intracellular microRNA imaging and combined specific-gene-targeting agents delivery for improved therapeutics, ACS Applied Mater. Interf. 7(20), 11015-11023 (2015) 510. Yaqiang Feng, Quanbo Wang, Jianping Lei, Huangxian Ju*, Electrochemiluminescent DNA sensing using carbon nitride nanosheets as emitter for loading of hemin labeled single-stranded DNA, Biosens. Bioelectron. 73, 7- 12 (2015) 511. Lei Zhang, Jianping Lei*, Fengjiao Ma, Pinghua Ling, Jintong Liu, Huangxian Ju*, A porphyrin photosensitized metal-organic framework for cancer cell apoptosis and caspase responsive theranostics, Chem. Commun. 51, 10831-10834 (2015) 512. Yurong Yan, Bo Shen, Hong Wang, Xue Sun, Wei Cheng, Hua Zhao, Huangxian Ju, Shijia Ding*, A novel and versatile nanomachine for ultrasensitive and specific detection of microRNAs based on molecular beacon initiated strand displacement amplification coupled with catalytic hairpin assembly with DNAzyme formation, Analyst 140, 5469-5474 (2015) 513. Lin Cui, Jie Wu, Huangxian Ju*, Synthesis of bismuth-nanoparticle-enriched nanoporous carbon on graphene for efficient electrochemical analysis of heavy-metal ions, Chem. Eur. J. 21, 11525-11530 (2015) 514. Guosong Lai*, Haili Zhang, Aimin Yu*, Huangxian Ju, In situ deposition of Prussian blue on mesoporous carbon nanosphere for sensitive electrochemical immunoassay, Biosens. Bioelectron. 74, 660-665 (2015) 515. Lin Cui, Jie Wu, Miaoqi Li, Huangxian Ju*, Highly sensitive electrochemical detection of mercury (II) via single ion-induced three-way junction of DNA, Electrochem. Commun. 59, 77-80 (2015) 516. Jiangwei Tian, Jinfeng Zhou, Zhen Shen, Lin Ding, Jun-Sheng Yu, Huangxian Ju*, A pH-activatable and aniline- substituted photosensitizer for near-infrared cancer theranostics, Chem. Sci. 6, 5969-5977 (2015) 517. Lei Zhang, Jianping Lei*, Jintong Liu, Fengjiao Ma, Huangxian Ju*, Persistent luminescence nanoprobe for biosensing and lifetime imaging of cell apoptosis via time-resolved fluorescence resonance energy transfer, Biomaterials 67, 323-334 (2015) 518. Jintong Liu, Lei Zhang, Jianping Lei*, Huangxian Ju, MicroRNA-responsive cancer cell imaging and therapy with functionalized gold nanoprobe, ACS Applied Mater. Interf. 7(34), 19016-19023 (2015) 519. Quanbo Wang, Nan Xu, Zhen Gui, Jianping Lei, Huangxian Ju*, Feng Yan*, Strand displacement activated peroxidase activity of hemin for fluorescent DNA sensing, Analyst 140, 6532-6537 (2015) 520. Miaoqi Li, Jie Wu, Lin Cui, Huangxian Ju*, Selective and sensitive electrochemical determination of Pb2+ based on highly adsorptive WOx-ethylenediamine nanowires, J. Electroanal. Chem. 757, 23-28 (2015) 521. Ruocan Qian, Lin Ding, Liwen Yan, Huangxian Ju*, Fluorescence imaging for in situ detection of cell surface sialic acid by competitive binding of 3-(dansylamino)phenylboronic acid, Anal. Chim. Acta 894, 85-90 (2015) 522. Zhen Gui, Feng Yan*, Jinchang Li, Mengyuan Ge，Huangxian Ju, Applications of locked nucleic acid molecular beacons in molecular recognition and bioanalysis, Chem. Prog. 桂珍, 严枫*, 李金昌, 葛梦圆, 鞠熀先, 锁核酸分子信标在分子识别与生物分析中的应用, 化学进展 27(10),1448-1458 (2015) 523. Lin Cui, Jie Wu, Jie Li, Huangxian Ju*, Electrochemical sensor for lead cation sensitized with a DNA functionalized porphyrinic metal-organic framework, Anal. Chem. 87(20), 10635-10641 (2015)

524. Li Jia, Lin Ding, Jiangwei Tian, Lei Bao, Yaoping Hu, Huangxian Ju*, Jun-Sheng Yu*, Aptamer loaded MoS2 nanoplates as nanoprobes for detection of intracellular ATP and controllable photodynamic therapy, Nanoscale 7, 15953-15961 (2015) 525. Qing Hao, Jianping Lei*, Quanbo Wang, Yang Zang, Huangxian Ju, Carbon nitride nanosheets sensitized quantum dots as photocathode for photoelectrochemical biosensing, J. Electroanal. Chem. 759, 8-13 (2015) 2016 36 papers 526. Dandan Li, Wei Cheng, Yurong Yan, Ye Zhang, Yibing Yin, Huangxian Ju*, Shijia Ding*, A colorimetric biosensor for detection of attomolar microRNA with a functional nucleic acid-based amplification machine, Talanta 146, 470-476 (2016)

527. Yang Zang, Jianping Lei*, Qing Hao, Huangxian Ju, CdS/MoS2 heterojunction-based photoelectrochemical DNA biosensor via enhanced chemiluminescence excitation, Biosens. Bioelectron. 77, 557-564 (2016) 528. Yin Huang, Jianping Lei*, Yan Cheng, Huangxian Ju, Ratiometric electrochemiluminescent strategy regulated by electrocatalysis of palladium nanocluster for immunosensing, Biosens. Bioelectron. 77, 733-739 (2016) 529. Yuehua Guo, Jie Wu, Jie Li, Huangxian Ju*, A plasmonic colorimetric strategy for biosensing through enzyme guided growth of silver nanoparticles on Au nanostars, Biosens. Bioelectron. 78, 267-273 (2016) 530. Jie Li, Jie Wu, Lin Cui, Mengmeng Liu, Feng Yan, Huangxian Ju*, Proximity hybridization-regulated electrochemical stripping of silver nanoparticles via nanogold induced deposition for immunoassay, Analyst 141, 131-136 (2016) 531. Yunlong Chen, Lin Ding, Wanyao Song, Min Yang, Huangxian Ju*, Protein-specific Raman imaging of glycosylation on single cells with zone-controllable SERS effect, Chem. Sci. 7, 569-574 (2016) 532. Qing Hao, Xiaonan Shan, Jianping Lei*, Yang Zang, Qianhui Yang, Huangxian Ju, A wavelength-resolved ratiometric photoelectrochemical technique: design and sensing applications, Chem. Sci. 7, 774-780 (2016) 533. Yaqiang Feng, Chunhui Dai, Jianping Lei, Huangxian Ju*, Yixiang Cheng*, Silole-containing polymer nanodot: An aqueous low-potential electrochemiluminescence emitter for biosensing, Anal. Chem. 88, 845-850 (2016) 534. P. Pedram, M. Mahani*, M. Torkzadeh-Mahani, Z. Hasani, Huangxian Ju, Cadmium sulfide quantum dots modified with the human transferrin protein siderophiline for targeted imaging of breast cancer cells, Microchim. Acta 183, 67-71 (2016) 535. Pinghua Ling, Jianping Lei*, Li Jia, Huangxian Ju, Platinum nanoparticles encapsulated metal−organic frameworks for the electrochemical detection of telomerase activity, Chem. Commun. 52, 1226-1229 (2016) 536. Jie Zhu, Xiaohe Huo, Xiaoqiang Liu*, Huangxian Ju*, Gold nanoparticles deposited polyaniline-TiO2 nanotube for surface plasmon resonance enhanced photoelectrochemical biosensing, ACS Applied Mater. Interf. 8, 341- 349 (2016) 537. Nan Xu, Jianping Lei*, Quanbo Wang, Qianhui Yang, Huangxian Ju, Dendritic DNA-porphyrin as mimetic enzyme for amplified fluorescent detection of DNA, Talanta 150, 661-665 (2016) 538. Lin Cui, Jie Wu, Huangxian Ju*, Label-free signal-on aptasensor for sensitive electrochemical detection of arsenite, Biosens. Bioelectron. 79, 861-865 (2016) 539. Dongquan Shi, Xingquan Xu, Yanqi Ye, Kai Song, Yixiang Cheng, Jin Di, Quanyin Hu, Jianxin Li, Huangxian Ju, Qing Jiang*, Zhen Gu*, Photo-cross-linked scaffold with kartogenin-encapsulated nanoparticles for cartilage regeneration, ACS Nano 10(1), 1292-1299 (2016) 540. Haifeng Dong, Songsong Tang, Yansong Hao, Haizhu Yu, Wenhao Dai, Guifeng Zhao, Yu Cao, Huiting Lu, Xueji Zhang*, Huangxian Ju, Fluorescent MoS2 quantum dots: Ultrasonic preparation, up-conversion and down- conversion bioimaging, and photodynamic therapy, ACS Applied Mater. Interf. 8(5), 3107-3114 (2016) 541. Yunlong Chen, Lin Ding, Wanyao Song, Min Yang, Huangxian Ju*, Liberation of protein-specific glycosylation information for glycan analysis by exonuclease III-aided recycling hybridization, Anal. Chem. 88, 2923-2928 (2016) 542. Jiangwei Tian, Yingping Luo, Liwei Huang, Yaqiang Feng, Huangxian Ju*, Bo-Yang Yu*, Pegylated folate and peptide-decorated graphene oxide nanovehicle for in vivo targeted delivery of anticancer drugs and therapeutic self-monitoring, Biosens. Bioelectron. 80(15), 519-524 (2016) 543. Aisha Bibi, Huangxian Ju*, Quantum dots assisted laser desorption/ionization mass spectrometric detection of carbohydrates: qualitative and quantitative analysis, J. Mass. Spectr. 51(4), 291-297 (2016) 544. Mengmeng Liu, Jie Wu*, Kaili Yang, Chen Zong, Jianping Lei, Huangxian Ju, Proximity hybridization-regulated chemiluminescence resonance energy transfer for homogeneous immunoassay, Talanta 154, 455-460 (2016) 545. Na Wu, Lei Bao, Lin Ding*, Huangxian Ju*, A single excitation-duplexed imaging strategy for profiling cell surface protein-specific glycoforms, Angew. Chem. Int. Ed. 55(17), 5220-5224 (2016) 546. Zhen Gui, Quanbo Wang, Jinchang Li, Mingchen Zhu, Lili Yu, Tang Xun, Feng Yan*, Huangxian Ju*, Direct detection of circulating free DNA extracted from serum samples of breast cancer using locked nucleic acid

molecular beacon, Talanta 154, 520-525 (2016) 547. Junjie Hu, Fei Liu, Huangxian Ju*, MALDI-MS patterning of caspase activities and its application in the assesement of drug resistance, Angew. Chem. Int. Ed. 55(23), 6667-6670 (2016) 548. Xiaohe Huo, Peipei Liu, Jie Zhu, Xiaoqiang Liu*, Huangxian Ju*, Electrochemical immunosensor constructed using TiO2 nanotubes as immobilization scaffold and tracing tag, Biosens. Bioelectron. 85, 698-706 (2016) 549. Dandan Li, Wei Cheng, Yujian Li, Yongjie Xu, Xinmin Li, Yibing Yin, Huangxian Ju*, Shijia Ding*, Catalytic hairpin assembly actuated DNA nanotweezer for logic gate building and sensitive enzyme-free biosensing of microRNAs, Anal. Chem. 88(15), 7500-7506(2016), 10.1021/acs.analchem.5b04844 550. Junjie Hu, Fei Liu, Nan Feng, Huangxian Ju*, Peptide codes for multiple protease activity assay via high-resolution mass spectrometric quantitation, Rapid Commun. Mass Spectr. 30, 196-201 (2016) 551. Yongjie Xu, Dandan Li, Wei Cheng, Rong Hu, Ye Sang, Yibing Yin, Shijia Ding*, Huangxian Ju*, Chemiluminescence imaging for microRNA detection based on cascade exponential isothermal amplification machinery, Anal. Chim. Acta 936, 229-235 (2016) 552. Guangming Wen, Huangxian Ju*, Enhanced photoelectrochemical proximity assay for highly selective protein detection in biological matrixes, Anal. Chem. 88, 8339-8345 (2016) 553. Liwen Yan, Jingjing Hui, Yiran Liu, Yuehua Guo, Lu Liu, Lin Ding*, Huangxian Ju, A cascade amplification approach for visualization of telomerase activity in living cells, Biosens. Bioelectron. 86, 1017-1023 (2016) 554. Wanyao Song, Lin Ding, Yunlong Chen, Huangxian Ju*, Plasmonic coupling of dual gold nanoprobes for SERS imaging of sialic acids on living cells, Chem. Commun. 52, 10640-10643 (2016) 555. Yongjie Xu, Xintong Bian, Ye Sang, Yujian Li, Dandan Li, Wei Cheng, Yibing Yin, Huangxian Ju, Shijia Ding*, Bis-three-way junction nanostructure and DNA machineries for ultrasensitive and specific detection of BCR/ABL fusion gene by chemiluminescence imaging, Sci. Rep. 6, 32370 (2016) doi:10.1038/srep32370 556. Aisha Bibi, Huangxian Ju*, Efficient enrichment of glycopeptides with sulfonic acid-functionalized mesoporous silica, Talanta 161, 681-685 (2016) 557. Md. Rajibul Akanda, Huangxian Ju*, A tyrosinase-responsive nonenzymatic redox cycling for amplified electrochemical immunosensing of protein, Anal. Chem. 88, 9856-9861 (2016) 558. Lei Bao, Lin Ding, Jingjing Hui, Huangxian Ju*, A light-up imaging protocol for neutral pH-enhanced fluorescence detection of lysosomal neuraminidase activity in living cells, Chem. Commun. 52, 12897-12900 (2016) 559. Pinghua Ling, Jianping Lei*, Huangxian Ju, Nanoscaled porphyrinic metal−organic frameworks for electrochemical detection of telomerase activity via telomerase triggered conformation switch, Anal. Chem. 88 (21), 10680-10686 (2016) 560. Yaqiang Feng, Feng Sun, Lizhen Chen, Jianping Lei, Huangxian Ju*, Ratiometric electrochemiluminescence detection of circulating tumor cells and cell-surface glycans, J. Electroanal. Chem. 781, 48–55 (2016) 561. Kewei Ren, Ying Liu, Jie Wu, Yue Zhang, Jing Zhu, MinYang, Huangxian Ju*, A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery, Nat. Commun. 7, 13580 (2016) 2017 25 papers 562. Yuzhe Xie, Shizhe Fu, Jie Wu*, Jianping Lei, Huangxian Ju, Motor-based microprobe powered by bio-assembled catalase for motion detection of DNA, Biosens. Bioelectron. 87, 31-37 (2017) 563. Liwei Huang, Yingping Luo, Xian Sun, Huangxian Ju, Jiangwei Tian*, Bo-Yang Yu*, An artemisinin-mediated ROS evolving and dual protease light-up nanocapsule for real-time imaging of lysosomal tumor cell death, Biosens. Bioelectron. 92, 724-732 (2017) 564. Jintong Liu, Lei Zhang, Jianping Lei*, Hong Shen, Huangxian Ju, Multifunctional metal−organic framework nanoprobe for cathepsin B-activated cancer cell imaging and chemo-photodynamic therapy, ACS Applied Mater. Interf. 9, 2150-2158 (2017) 565. Binto Simon, Xuexia Huang, Huangxian Ju, Guoxuan Sun, Min Yang*, Synthesis and characterization of photoaffinity labelling reagents towards the Hsp90 C-terminal domain, Org. Biomol. Chem. 15, 1597-1605 (2017) (cover paper) 566. Sheng Zhou, Wanli Lu, Liang Chen, Qiteng Ge, Dongyang Chen, Zhihong Xu, Dongquan Shi, Jin Dai, Jianxin Li, Huangxian Ju, Yi Cao, Jinzhong Qin, Shuai Chen, Huajian Teng, Qing Jiang*, AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice, Sci. Rep. 7, 43245 (2017) 567. Yingping Luo, Liwei Huang, Ye Yang, Xianfei Zhuang, Siyao Hu, Huangxian Ju, Bo-Yang Yu*, Jiangwei Tian*, A programmed nanoparticle with self-adapting for accurate cancer cell eradication and therapeutic self-reporting, Theranostics 7(5), 1245-1256 (2017) 568. Xiaoqiang Liu*, Xiaohe Huo, Peipei Liu, Yunfei Tang, Jun Xu, Huangxian Ju*, TiO2 nanowire arrays modified

with a simultaneous “etching, doping and deposition” technique for ultrasensitive amperometric immunosensing, Biosens. Bioelectron. 92, 171-178 (2017) 569. Huangxian Ju*, Signal amplification for highly sensitive immunosensing, J. Anal. Testing 1, 7 (2017) 570. Jielin Chen, Yuehua Guo, Jun Zhou*, Huangxian Ju*, The effect of adenine repeats on G-quadruplex/hemin peroxidase mimicking DNAzyme activity, Chem. Eur. J. 23, 4210-4215 (2017) 571. Yuehua Guo, Kaili Yang, Jiachen Sun, Jie Wu, Huangxian Ju*, A pH-responsive colorimetric strategy for DNA detection by acetylcholinesterase catalyzed hydrolysis and cascade amplification, Biosens. Bioelectron. 94, 651-656 (2017) 572. Yang Zang, Jianping Lei*, Huangxian Ju, Principles and applications of photoelectrochemical sensing strategies based on biofunctionalized nanostructures, Biosens. Bioelectron. 96, 8-16 (2017) 573. Lei Zhang, Fengjiao Ma, Jianping Lei*, Jintong Liu, Huangxian Ju*, Target-triggered cascade assembly of a catalytic network as an artificial enzyme for highly efficient sensing, Chem. Sci. 8, 4833-4839 (2017) 574. Yuhang Ji, Lei Zhang, Longyi Zhu, Jianping Lei*, Jie Wu, Huangxian Ju, Binding-induced DNA walker for signal amplification in highly selective electrochemical detection of protein, Biosens. Bioelectron. 96, 201-205 (2017) 575. Jun Zhou*, Samir Amrane, Frédéric Rosu, Gilmar F. Salgado, Yunqiang Bian, Hisae Tateishi-Karimata, Eric Largy, Dursun Nizam Korkut, Anne Bourdoncle, Daisuke Miyoshi, Jian Zhang, Huangxian Ju, Wei Wang*, Naoki Sugimoto, Valérie Gabelica, Jean-Louis Mergny*, Unexpected position-dependent effects of ribose G-quartets in G-quadruplexes, J. Am. Chem. Soc. 139, 7768-7779 (2017) 576. Jingjing Hui, Lei Bao, Siqiao Li, Yi Zhang, Yimei Feng, Lin Ding*, Huangxian Ju*, Localized chemical remodeling for live cell imaging of protein-specific glycoform, Angew. Chem. Int. Ed. 56, 8139-8143 (2017) 577. Shizhe Fu, Xueqing Zhang, Yuzhe Xie, Jie Wu*, Huangxian Ju, An efficient enzyme-powered micromotor device fabricated by cyclic alternate hybridization assembly for DNA detection, Nanoscale 9, 9026-9033 (2017) 2+ 578. Yaqiang Feng, Feng Sun, Ningning Wang, Jianping Lei, Huangxian Ju*, Ru(bpy)3 incorporated luminescent polymer dots: Double-enhanced electrochemiluminescence for detection of single-nucleotide polymorphism, Anal. Chem. 89, 7659-7666 (2017) 579. Jingxing Guo, Yunlong Chen, Yongjia Jiang, Huangxian Ju*, Polyadenine-modulated DNA conformation monitored by surface-enhanced Raman scattering (SERS) on multibranched gold nanoparticles and its sensing application, Chem. Eur. J. 23, 9332-9337 (2017) 580. Kosar shahsavar, Morteza Hosseini*, Ehsan shokri, Mohammad Reza Ganjali, and Huangxian Ju, A sensitive colorimetric aptasensor with a triple-helix molecular switch based on peroxidase-like activity of a DNAzyme for ATP detection, Anal. Methods 9, 4726-4731 (2017) 581. Peipei Liu, Xiaoqiang Liu*, Xiaohe Huo, Yunfei Tang, Jun Xu, Huangxian Ju*, TiO2–BiVO4 heterostructure to enhance photoelectrochemical efficiency for sensitive aptasensing, ACS Applied Mater. Interf. 9, 27185-27192 (2017) 582. Kaili Yang, Min Huo, Yuehua Guo, Yizhuo Yang, Jie Wu*, Lin Ding*, Huangxian Ju, Target-induced cyclic DNAzyme formation for colorimetric and chemiluminescence imaging assay of protein biomarkers, Analyst 142, 3740-3746 (2017) 583. Xiaoyan Zhou, Min Zhao, Xiaolei Duan, Bin Guo, Wei Cheng, Shijia Ding*, Huangxian Ju*, Collapse of DNA tetrahedron nanostructure for “off-on” fluorescence detection of DNA methyltransferase activity, ACS Applied Mater. Interf. 9(46), 40087-40093 (2017) 584. Qianhui Yang, Qing Hao, Jianping Lei*, Huangxian Ju*, Photoelectron-regulated redox reaction of polyaniline for visual detection of trace copper, Chin. Anal. Chem. 杨芊荟,郝青,雷建平*,鞠熀先*,光电子调控的聚苯胺氧化还原反应用于铜离子可视化检测, 分析化学 45(12), 1895-1902 (2017) 585. Yuehua Guo, Jielin Chen, Mingpan Cheng, David Monchaud, Jun Zhou*, Huangxian Ju*, A thermophilic tetramolecular G-quadruplex/hemin DNAzyme, Angew. Chem. Int. Ed. 56(52), 16636-16640 (2017) 586. Md. Rajibul Akanda, Huangxian Ju*, An integrated redox cycling for electrochemical enzymatic signal enhancement, Anal. Chem. 89(24), 13480-13486 (2017) 2018 43 papers 587. Feng Sun, Ziyu Wang, Yaqiang Feng, Yixiang Cheng, Huangxian Ju*, Yiwu Quan*, Electrochemiluminescent resonance energy transfer of polymer dots for aptasensing, Biosens. Bioelectron. 100, 28-34 (2018) 588. Huangxian Ju*, Functional nanomaterials and nanoprobes for amplified biosensing, Appl. Mater. Today 10, 51- 71 (2018) 589. Yunlong Chen, Huipu Liu, Yingying Xiong, Huangxian Ju*, Quantitative screening of cell-surface gangliosides by nondestructive extraction and hydrophobic collection, Angew. Chem. Int. Ed. 57(3), 785-789 (2018)

590. Yaqiang Feng, Ningning Wang, Huangxian Ju*, Highly efficient electrochemiluminescence of cyanovinylene- contained polymer dots in aqueous medium and its application in imaging analysis, Anal. Chem. 90(2), 1202- 1208 (2018) 591. Xiao Meng, Junjie Hu, Zhicong Chao, Ying Liu*, Huangxian Ju, Quan Cheng*, Thermoresponsive arrays patterned via photoclick chemistry: Smart MALDI plate for protein digest enrichment, desalting, and direct MS analysis, ACS Applied Mater. Interf. 10, 1324-1333 (2018) 592. Kewei Ren, Yifan Xu, Ying Liu*, Min Yang, Huangxian Ju*, A responsive “nano string light” for highly efficient mRNA imaging in living cells via accelerated DNA cascade reaction, ACS Nano 12(1), 263-271 (2018) 593. Yicheng Wei, Xiang Ren, Hongmin Ma, Xu Sun, Yong Zhang, Xuan Kuang, Tao Yan, Huangxian Ju, Dan Wu*, Qin Wei*, CoC2O4·2H2O derived Co3O4 nanorods array: a high-efficiency 1D electrocatalyst for alkaline oxygen evolution reaction, Chem. Commun. 54, 1533-1536 (2018) 594. Jayakumar Kumarasamy, María Belén Camarada, Dharuman Venkatraman*, Huangxian Ju, Ramendra Sundar Dey*, Yangping Wen*, One-step coelectrodeposition-assisted layer-by-layer assembly of gold nanoparticles and reduced graphene oxide and its self-healing three-dimensional nanohybrid for an ultrasensitive DNA sensor, Nanoscale 10, 1196-1206 (2018) 595. Ke Lu, Tianshu Shi, Lan Li, Kaijia Zhang, Xiaobo Zhu, Siyu Shen, Fei Yu, Huajian Teng, Xiang Gao, Huangxian Ju, Wei Wang, Qing Jiang*, Zhuangguguanjie formulation protects articular cartilage from degeneration in joint instability-induced murine knee osteoarthritis, Am. J. Transl. Res. 10(2), 411-421 (2018) 596. Longyi Zhu, Jun Zhou, Guohua Xu, Conggang Li, Pinghua Ling, Bin Liu*, Huangxian Ju*, Jianping Lei*, DNA quadruplexes as molecular scaffolds for controlled assembly of fluorogens with aggregation-induced emission, Chem. Sci. 9, 2559-2566 (2018) 597. Yue Zhang, Kewei Ren, Xiaobo Zhang, Zhicong Chao, Yuqin Yang, Deju Ye, Zhihui Dai, Ying Liu*, Huangxian Ju*, Photo-tearable tape close-wrapped upconversion nanocapsules for near-infrared modulated efficient siRNA delivery and therapy, Biomaterials 163, 55-66 (2018) 598. Yunlong Chen, Huipu Liu, Lin Ding, Huangxian Ju*, Functional dual-color indicator to achieve in situ visualization of intracellular glycosylation, Anal. Chem. 90, 3073-3078 (2018) 599. Qianhui Yang, Qing Hao, Jianping Lei*, Huangxian Ju, Portable photoelectrochemical device integrated with self- powered electrochromic tablet for visual analysis, Anal. Chem. 90, 3703-3707 (2018) 600. Yunlong Chen, Lin Ding, Huangxian Ju*, In situ cellular glycan analysis, Acc. Chem. Res. 51(4), 890-899 (2018) 601. Jing Zhu, Haiying Gan, Jie Wu, Huangxian Ju*, Molecular machine powered surface programatic chain reaction for highly sensitive electrochemical detection of protein, Anal. Chem. 90(8), 5503-5508 (2018) 602. Yawei Wang, Jingxing Guo, Yuehua Guo, Xiaobo Zhang,Huangxian Ju*, Enzymatically driven formation of palindromic DNA-Au nanoparticles for snowball assembly and colorimetric biosensing, Sens. Actuat. B Chem. 267, 328-335 (2018) 603. Jintong Liu, Ping Du, Hui Mao, Lei Zhang, Huangxian Ju*, Jianping Lei*, Dual-triggered oxygen self-supply black phosphorus nanosystem for enhanced photodynamic therapy, Biomaterials 172, 83-91 (2018)

604. Lizhen Chen, Ying Fu, Naixiang Wang, Anneng Yang, Yuanzhe Li, Jie Wu, Huangxian Ju*, Feng Yan*, Organic electrochemical transistors for the detection of cell surface glycans, ACS Applied Mater. Interf. 10(22), 18470- 18477 (2018) 605. Yasaman-Sadat Borghei, Morteza Hosseini*, Mohammad Reza Ganjali, Huangxian Ju, Colorimetric and energy transfer based fluorometric turn-on method for determination of microRNA using silver nanoclusters and gold nanoparticles, Microchim. Acta 185, 286-294 (2018) 606. Longyi Zhu, Qihui Liu, Bangyu Yang, Huangxian Ju, Jianping Lei*, Pixel counting of fluorescence spots triggered by DNA walkers for ultrasensitive quantification of nucleic acid, Anal. Chem. 90(11), 6357-6361 (2018) 607. Jin Dai, Sheng Zhou, Qiting Ge, Jinzhong Qin, Dongyang Chen, Zhihong Xu, Dongquan Shi, Jianxin Li, Huangxian Ju, Yi Cao, Minghao Zheng, ChaoJun Li, Xiang Gao, Huajian Teng, Qing Jiang*, Bi-directional regulation of cartilage metabolism by inhibiting BET proteins-- analysis of the effect of I-BET151 on human chondrocytes and murine joints, J. Orthop. Surg. Res. 13, 118 (2018) 608. Ke Lu, Tian-Shu Shi, Si-Yu Shen, Wan-Li Lu, Jing Wu, Kai-Jia Zhang, Xiao-Bo Zhu, Yong Shi, Xiang-Lin Liu, Fei Yu, Lan Li, Hua-jian Teng, Xiang Gao, Huangxian Ju, Wei Wang, Chao-Jun Li, Qing Jiang*, Bin Xue*, Egr1 deficiency disrupts dynamic equilibrium of chondrocyte extracellular matrix through PPARγ/RUNX2 signaling pathways, Am. J. Translat. Res. 10(6), 1620-1632 (2018)

609. Ningning Wang, Yaqiang Feng, Yawei Wang, Huangxian Ju*, Feng Yan*, Electrochemiluminescent imaging for multi-immunoassay sensitized by dual DNA amplification of polymer dot signal, Anal. Chem. 90, 7708-7714 (2018) 610. Jingxing Guo, Ying Liu, Yunlong Chen, Jianqi Li, Huangxian Ju*, A multifunctional SERS sticky note for real- time quorum sensing tracing and inactivation of bacterial biofilms, Chem. Sci. 9, 5906-5911 (2018) This article is part of the themed collection: 2018 Chemical Science HOT Article Collection 611. Md. Rajibul Akanda, Huangxian Ju*, Ferritin-Triggered Redox Cycling for highly sensitive electrochemical immunosensing of protein, Anal. Chem. 90, 8028-8034 (2018) 612. Yunfei Tang, Yun Chai, Xiaoqiang Liu*, Lele Li, Liwei Yang, Peipei Liu, Yanmei Zhou, Huangxian Ju*, Yunzhi Cheng, A photoelectrochemical aptasensor constructed with core-shell CuS-TiO2 heterostructure for detection of microcystin-LR, Biosens. Bioelectron. 117, 224-231 (2018) 613. Kumarasamy Jayakumar*, María Belén Camarada, Venkataraman Dharuman*, Rajendiran Rajesh, Rengarajan Venkatesan, Huangxian Ju, Mahalingam Maniraj, Abhishek Rai, Sudipta Roy Barman, Yangping Wen*, Layer- by-layer-assembled AuNPs-decorated first-generation poly (amidoamine) dendrimer with reduced graphene oxide core as highly sensitive biosensing platform with controllable 3D nanoarchitecture for rapid voltammetric analysis of ultratrace DNA hybridization, ACS Applied Mater. Interf. 10, 21541-21555 (2018) 614. Hong Shen, Jintong Liu, Jianping Lei*, Huangxian Ju, A core-shell nanoparticle-peptide@metal-organic framework as pH and enzyme dual-recognition switch for stepwise-responsive imaging in living cells, Chem. Commun. 54(66), 9155-9158 (2018) 615. Xiao-yan Zhou, Jian-hua Pan, Yong-neng Ma, Xiu-juan Peng, Hai-ping Wu, Qin Zhou, Shi-jia Ding*, Huang-xian Ju*, An ultrasensitive fluorescence sensing strategy for detection and in situ imaging of chronic myeloid leukemia- related BCR-ABL1 mRNA, Sens. Actuat. B Chem. 273, 1456-1462 (2018) 616. Jingxing Guo, Yunlong Chen, Jianqi Li, Jintong Liu, Huangxian Ju*, A self-calibrated 2D nanoarchitecture for label-free SERS quantitation and distribution imaging of target, Sens. Actuat. B Chem. 273, 211-219 (2018) 617. Qing Xiao, Jie Wu*, Pengyun Dang, Huangxian Ju, Multiplexed chemiluminescence imaging assay of protein biomarkers using DNA microarray with proximity binding-induced hybridization chain reaction amplification, Anal. Chim. Acta 1032, 130-137 (2018) 618. Siqiao Li, Yiran Liu, Lu Liu, Yimei Feng, Lin Ding*, Huangxian Ju*, A hierarchical coding strategy for live cell imaging of protein-specific glycoform, Angew. Chem. Int. Ed. 57, 12007-12011 (2018) 619. Ziyu Wang, Yaqiang Feng, Ningning Wang, Yixiang Cheng*, Yiwu Quan*, Huangxian Ju*, Donor-acceptor conjugated polymer dots for tunable electrochemiluminescence activated by aggregation-induced emission-active moieties, J. Phys. Chem. Lett. 9(18), 5296-5302 (2018) 620. Kumarasamy Jayakumar*, María Belén Camarada, Rajendiran Rajesh, Rengarajan Venkatesan, Huangxian Ju, Venkataraman Dharuman*, Yangping Wen*, Layer-by-layer assembled gold nanoparticles/lower-generation (Gn≤3) polyamidoamine dendrimers-grafted reduced graphene oxide nanohybrids with 3D fractal architecture for fast, ultra-trace, and lable-free electrochemical gene nanobiosensors, Biosens. Bioelectron. 120, 55-63 (2018) 621. Yifeng Zhang, Rui Xu, Qing Kang, Yong Zhang, Qin Wei*, Yaoguang Wang, Huangxian Ju, Ultrasensitive photoelectrochemical biosensing platform for detecting N-terminal pro-brain natriuretic peptide based on SnO2/SnS2/mpg-C3N4 amplified by PbS/SiO2, ACS Applied Mater. Interf. 10(37), 31080-31087 (2018) 622. Chen Zong, Jie Wu, Yang Zang, Huangxian Ju*, Resonance energy transfer and electron-hole annihilation induced chemiluminescence of quantum dots for amplified immunoassay, Chem. Commun. 54, 11861-11864 (2018) 623. Tingyuan Lang, Xiaojuan Ding, Liangsheng Kong, Xiaoyan Zhou, Zhiqi Zhang, Huangxian Ju*, Shijia Ding*, NFATC2 is a novel therapeutic target for colorectal cancer stem cells, OncoTargets and Therapy 11, 6911-6924 (2018) 624. Rui Xu, Dong Wei, Bin Du, Wei Cao, Dawei Fan, Yong Zhang*, Qin Wei, Huangxian Ju, A photoelectrochemical sensor for highly sensitive detection of amyloid beta based on sensitization of Mn:CdSe to Bi2WO6/CdS, Biosens. Bioelectron. 122, 37-42 (2018) 625. Yimei Feng, Yuna Guo, Yiran Li, Jing Tao, Lin Ding*, Jie Wu*, Huangxian Ju, Lectin-mediated in situ rolling circle amplification on exosomes for probing cancer-related glycan pattern, Anal. Chim. Acta 1039, 108-115 (2018) 626. Jielin Chen, Yingying Zhang, Mingpan Cheng, Yuehua Guo, Jiri Šponer, David Monchaud, Jean-Louis Mergny, Huangxian Ju*, Jun Zhou*, How proximal nucleobases regulate the catalytic activity of G-quadruplex/hemin DNAzymes, ACS Catalysis 8, 11352-11361 (2018) 627. Ke Lu, Fei Yu, Tianshu Shi, Siyu Shen, Lan Li, Yixuan Li, Jiaxuan Jiang, Xiang Gao, Huangxian Ju, Wei Wang, Huajian Teng, Qing Jiang*, Seasonal variance of serum biomarker levels in osteoarthritis patients: a cross-sectional study of 104 patients, Int. J. Clin. Exp. Med. Int. J. Clin. Exper. Med. 11(10), 10774-10780 (2018)

628. Kewei Ren, Yue Zhang, Xiaobo Zhang, Ying Liu*, Min Yang, Huangxian Ju*, In situ siRNA assembly in living cells for gene therapy with microRNA triggered cascade reactions templated by nucleic acids, ACS Nano 12(11), 10797-10806 (2018) 629. Tingting Yan, Longyi Zhu, Huangxian Ju, Jianping Lei*, DNA-walker-induced allosteric switch for tandem signal amplification with palladium nanoparticles/metal-organic framework tags in electrochemical biosensing, Anal. Chem. 90, 14493-14499 (2018) 2019 43 papers 630. Yingying Zhang, Jielin Chen, Huangxian Ju*, Jun Zhou*, Thermal denaturation profile: a straightforward signature to characterize parallel G-quadruplexs, Biochimie 157, 22-25 (2019) 631. Jintong Liu, Ping Du, Tianrui Liu, Bernardino J. Córdova Wong, Weiping Wang, Huangxian Ju, Jianping Lei*, A black phosphorus/manganese dioxide nanoplatform: oxygen self-supply monitoring, photodynamic therapy enhancement and feedback, Biomaterials 192, 179-188 (2019) 632. Lei Zhang, Jun Zhou, Fengjiao Ma, Quanbo Wang, Hui Xu*, Huangxian Ju*, Jianping Lei*, Single-sided competitive axial coordination of G-quadruplex/hemin as molecular switch for imaging intracellular nitric oxide, Chem. Eur. J. 25, 490-494 (2019) 633. Yasamn Sadat Borghei, Morteza Hosseini*, Mohammad Reza Ganjali, Huangxian Ju*, A unique FRET approach toward detection of single base-pair mismatch DNA in BRCA1 gene, Mater. Sci. Engineering C 97, 406-411 (2019) 634. Sina Wang, Yuhang Ji, Haomin Fu, Huangxian Ju, Jianping Lei*, A rolling circle amplification-assistant DNA walker triggered by multiple DNAzyme cores for highly sensitive electrochemical biosensing, Analyst 144, 691- 697 (2019) 635. Xiaoyan Zhou, Yujian Li, Haiping Wu, Wei Huang, Huangxian Ju, Shijia Ding*, An amperometric immunosensor for sensitive detection of circulating tumor cells using tyramide signal amplification-based layer-by-layer deposited electroactive infinite coordination polymer, Biosens. Bioelectron. 130, 88-94 (2019) 636. Min Huo, Siqiao Li, Peiwen Zhang, Yimei Feng, Yiran Liu, Na Wu, Huangxian Ju, Lin Ding*, Nanoamplicon comparator for live-cell microRNA imaging, Anal. Chem. 91, 3374-3381 (2019) 637. Mohamad Mahani, Zhahra Mousapour, Faten Divsar Mohamad Mahani*, Huangxian Ju, A carbon dot and molecular beacon based fluorometric sensor for the cancer marker microRNA-21, Microchim. Acta 186(3), 132, 2019 638. Jianshe Tang, Weiwei Chen, Huanxian Ju*, Rapid detection of pesticide residue using a silver coated glass bead as nonplanar SERS substrate, Sens. Actuat. B 287, 576-583 (2019) 639. Yueyuan Li, Yaoguang Wang, Nuo Zhang, Dawei Fan, Lei Liu, Tao Yan, Xinglong Yang, Qin Wei*, Huangxian Ju, Magnetic electrode-based electrochemical immunosensor using amorphous bimetallic sulfides of CoSnSx as signal amplifier for the NT‒pro BNP detection, Biosens. Bioelectron. 131, 250-256 (2019) 640. Yanrong Qian, Jinhui Feng, Dawei Fan, Yong Zhang, Xuan Kuang, Huan Wang*, Qin Wei*, Huangxian Ju, A sandwich-type photoelectrochemical immunosensor for NT-pro BNP detection based on F-Bi2WO6/Ag2S and GO/PDA for signal amplification, Biosens. Bioelectron. 131, 299-306 (2019) 641. Jin Dai, Sheng Zhou, Qiting Ge, Jinzhong Qin, Jianxin Li, Huangxian Ju, Yi Cao, Minghao Zheng, ChaoJun Li, Xiang Gao, Huajian Teng*, Qing Jiang*, Recruitment of Brd3 and Brd4 to acetylated chromatin is essential for proinflammatory cytokine-induced matrix-degrading enzymes expression, J. Orthop. Surg. Res. 14, 59 (2019) 642. Juan-juan Li, Jie Wu, Zheng-qing He, Hua Pei, Qiang-feng Xia, Qiang Wu*, Huangxian Ju *, Fast detection of mycoplasma pneumoniae by interaction of tetramolecular G-quadruplexes with graphene oxide, Sens. Actuat. B 290, 41-46 (2019) 643. Jingwei Xue, Lei Yang, Huan Wang*, Tao Yan, Dawei Fan, Rui Feng, Bin Du, Qin Wei*, Huangxian Ju, Quench- type electrochemiluminescence immunosensor for detection of amyloid β-protein based on resonance energy transfer from luminol@SnS2-Pd to Cu doped WO3 nanoparticles, Biosens. Bioelectron. 133, 192-198 (2019) 644. Junjie Hu, Fei Liu, Nan Feng, Huangxian Ju*, Selenium-isotopic signature toward mass spectrometric identification and enzymatic activity assay with enhanced confidence, Anal. Chim. Acta 1064, 1-10 (2019) Cover paper 645. Xueqing Zhang, Chengtao Chen, Jie Wu*, Huangxian Ju, Bubble-propelled jellyfish-like micromotors for DNA sensing, ACS Applied Mater. Interf. 11(14), 13581-13588 (2019) 646. Jianshe Tang, Weiwei Chen, Huanxian Ju*, Sensitive surface-enhanced Raman scattering detection of atrazine based on aggregation of silver nanoparticles modified carbon quantum dots Talanta 201, 45-51 (2019) 647. Yiran Liu, Lu Liu, Siqiao Li, Guyu Wang, Huangxian Ju, Lin Ding*, Filter beacon: A gating-free architecture for protein-specific glycoform imaging on cell surface, Anal. Chem. 91, 6027-6034 (2019)

648. Chao Wang, Nuo Zhang, Yueyuan Li, Lei Yang, Dong Wei, Tao Yan, Huangxian Ju, Bin Du, Qin Wei*, Cobalt- based metal-organic frameworks as co-reaction accelerator for enhancing electrochemiluminescence behavior of N-(aminobutyl)-N-(ethylisoluminol) and ultrasensitive immunosensing of amyloid-β protein, Sens. Actuat. B 291, 319-328 (2019) 649. Shan-Shan Lai, Xiao Fu, Zi-Han Yu, En-Ze Jiang, Dan-Dan Zhao, De-Cai Yu, Yu-Dong Qiu, Xiang Gao, Huang- Xian Ju, Wei Wang, Qing Jiang, Min-Sheng Zhu, Chao-Jun Li, Bin Xue*, HSC-specific knockdown of GGPPS alleviated CCl4-induced chronic liver fibrosis through mediating RhoA/Rock pathway, Am. J. Transl. Res. 11(4), 2382-2392 (2019) (www.ajtr.org) 650. Haiying Gan, Jie Wu*, Huangxian Ju, Proximity hybridization-induced on particle DNA walker for ultrasensitive protein detection, Anal. Chim. Acta 1074, 142-149 (2019) 651. Jing Huang, Longyi Zhu, Huangxian Ju, Jianping Lei*, Telomerase triggered DNA walker with a superhairpin structure for human telomerase activity sensing, Anal. Chem. 91(11), 6981-6985 (2019) 652. Lei Yang, Dawei Fan, Yong Zhang, Caifeng Ding, Dan Wu, Qin Wei*, Huangxian Ju, Ferritin-based electrochemiluminescence nanosurface energy transfer system for procalcitonin detection using HWRGWVC heptapeptide for site-oriented antibody immobilization, Anal. Chem. 91(11), 7145-7152 (2019) 653. Chengtao Chen, Zhengqing He, Jie Wu*, Xueqing Zhang, Qianfeng Xia, Huangxian Ju*, Motion of enzyme powered microshell motors, Chem. - An Asian J. 14, 2491-2496 (2019) 654. Ningning Wang, Ziyu Wang, Lizhen Chen, Weiwei Chen, Yiwu Quan, Yixiang Cheng*, Huangxian Ju*, Dual resonance energy transfer-enhanced electrochemiluminescence of triple-component polymer dots for analysis of membrane proteins, Chem. Sci. 10, 6815-6820 (2019) 655. Liwei Yang, Xiaoqiang Liu*, Lele Li, Hejie Zheng, Si Zhang, Yunfei Tang, Huangxian Ju*, A visible light photoelectrochemical sandwich aptasensor for adenosine triphosphate based on MgIn2S4-TiO2 nanoarray heterojunction, Biosens. Bioelectron. 142, 111487 (2019) 656. Sheng Zhou, Yixuan Li, Lian Qiao, Yuxiang Ge, Xiaojing Huang, Xiang Gao, Huangxian Ju, Wei Wang, Junfeng Zhang, Jun Yan, Huajian Teng, Qing Jiang*, Inactivation of Lkb1 in postnatal chondrocytes leads to epiphyseal growth-plate abnormalities and promotes enchondroma-like formation, FASEB J. 33, 9476-9488 (2019) 657. Yingying Xiong, Yunlong Chen, Lin Ding, Xiaoqiang Liu, Huangxian Ju*, Fluorescent visual quantitation of cell- secreted sialoglycoconjugates by chemoselective recognition and hybridization chain reaction, Analyst 144, 4545- 4551 (2019) 658. Jingwei Xue, Lei Yang, Yue Jia, Yong Zhang, Dan Wu, Hongmin Ma, Lihua Hu*, Qin Wei*, Huangxian Ju, Dual- quenching electrochemiluminescence resonance energy transfer system from Ru-In2S3 to α-MoO3-Au based on protect of protein bioactivity for procalcitonin detection, Biosens. Bioelectron. 142, 11524 (2019) 659. Xiaobo Zhang, Weiwei Chen, Xiaoyu Xie, Yuyi Li, Desheng Chen, Zhicong Chao, Chenghui Liu, Haibo Ma, Ying Liu* Huangxian Ju*, Boosting luminance energy transfer efficiency in upconversion nanoparticles with an energy concentrated zone, Angew. Chem. Int. Ed. 58 (35), 12117-12122 (2019) 660. Chao Wang, Nuo Zhang, Dong Wei, Rui Feng, Dawei Fan, Lihua Hu*, Qin Wei*, Huangxian Ju, Double 2+ electrochemiluminescence quenching effects of Fe3O4@PDA-CuXO towards self-enhanced Ru(bpy)3 functionalized MOFs with hollow structure and it application to procalcitonin immunosensing, Biosens. Bioelectron. 142, 111551 (2019) 661. Lei Yang, Jingwei Xue, Yue Jia, Yong Zhang, Dan Wu, Hongmin Ma, Qin Wei*, Huangxian Ju, Construction of well-ordered electrochemiluminescence sensing interface using peptide-based specific antibody immobilizer and N-(aminobutyl)-N-(ethylisoluminol) functionalized ferritin as signal indicator for procalcitonin analysis Biosens. Bioelectron. 142, 11562 (2019) 662. Lina Wu, Yingfei Wang, Yue Zhang, Yuling He, Chao Wang, Zhenda Lu, Ying Liu*, Huangxian Ju, Fluorescence hydrogel array based on interfacial cation exchange amplification for highly sensitive microRNA detection, Anal. Chim. Acta 1080, 206-214 (2019) 663. Yanrong Qian, Jinhui Feng, Huan Wang, Dawei Fan, Na Jiang*, Qin Wei*, Huangxian Ju, Sandwich-type signal- off photoelectrochemical immunosensor based on dual suppression effect of PbS quantum dots/Co3O4 polyhedron as signal amplification for procalcitonin detection, Sens. Actuat. B 300, 127001 (2019) 664. Peiwen Zhang, Yiran Li, Xiaofei Yu, Huangxian Ju, Lin Ding*, Switchable enzymatic accessibility for precision cell-selective surface glycan remodeling, Chem. Eur. J. 25, 10505-10510 (2019) 665. Rui Xu, Rui Feng, Dong Wei, Tao Yan, Yong Zhang, Wei Cao, Qin Wei*, Huangxian Ju, A novel photoelectrochemical singal amplification assay for procalcitonin detection based on ZnxBi2S3+x sensitized NiTiO3 matrix, Sens. Actuat. B 301, 127099 (2019)

666. Jingxing Guo, Zhihao Zhong, Yumei Li, Ying Liu*, Ruiyong Wang*, Huangxian Ju*, A “three-in-one” SERS adhesive tape for rapid sampling, release and detection of wound infectious pathogens, ACS Applied Mater. Interf. 11, 36399-36408 (2019) 667. Yuling He, Shuwen Guo, Lina Wu, Pengwen Chen, Leyong Wang, Ying Liu*, Huangxian Ju*, Near-infrared boosted ROS responsive siRNA delivery and cancer therapy with sequentially peeled upconversion nano-onions, Biomaterials 225, 119501 (2019) 668. Jingwei Xue, Lei Yang, Yue Jia, Huan Wang, Nuo Zhang, Xiang Ren, Hongmin Ma,* Qin Wei, Huangxian Ju, Electrochemiluminescence double quenching system based on novel emitter GdPO4:Eu with low-excited positive potential for ultrasensitive procalcitonin detection, ACS Sensors 4, 2825-2831 (2019) 669. Lei Yang, Yue Jia, Dan Wu, Yong Zhang, Huangxian Ju, Yu Du, Hongmin Ma*, Qin Wei*, Synthesis and application of CeO2/SnS2 heterostructures as a highly-efficient coreaction accelerator in luminol-dissolved O2 system for ultrasensitive biomarkers immunoassay Anal. Chem. 71, 14066-14073 (2019) 670. Jielin Chen, Yingying Zhang, Mingpan Cheng, Jean-Louis Mergny, Qianmei Lin, Jun Zhou*, Huangxian Ju*, Highly active G-quadruplex/hemin DNAzyme for ultrasensitive determination of lead ion, Microchim. Acta 186, 786 (2019) 671. Yue Zhang, Yue Zhang, Guobin Song, Yuling He, Xiaobo Zhang, Ying Liu* Huangxian Ju*, A DNA-azobenzene nanopump fueled by upconversion luminance for controllable intracellular drug release Angew. Chem. Int. Ed. 58 (50), 18207-18211 (2019) 672. Yingying Xiong (熊莹莹), Yunlong Chen (陈云龙), Huangxian Ju (鞠熀先)*, Glycan analysis in cellular secretion (细胞分泌物中的聚糖分析), Acta Chim. Sinica (化学学报) 77(12), 1221-1229 (2019) 2020 24+6 673. Ziyu Wang, Ningning Wang, Hang Gao, Yiwu Quan*, Huangxian Ju*, Yixiang Cheng*, Amplified electrochemiluminescence signals promoted by AIE-active moiety of D-A type polymer dots or biosensing, Analyst 145, 233-239 (2020) 674. Tao Yan, Tingting Wu, Shiyan Wei, Haoqi Wang, Meng Sun, Liangguo Yan, Qin Wei*, Huangxian Ju, Photoelectrochemical competitive immunosensor for 17β-estradiol detection based on ZnIn2S4/NH2-MIL-125(Ti) amplified by PDA NS/Mn:ZnCdS Biosens. Bioelectron. 148, 111739 (2020) 675. Longyi Zhu, Yang Li, Yunjie Wen, Huangxian Ju, Jianping Lei*, Controlled assembly of AIEgens based on a super-quadruplex scaffold for detection of plasma membrane proteins, Anal. Chim. Acta 1094, 130-135 (2020) 676. Ying Hou, Zhaoxuan Liu, Lei Tong, Lu Zhao, Xuan Kuang*, Rui Kuang*, Huangxian Ju, One-step Electrodeposition of MOF@CCQDs/NiF Electrode for Chiral Recognition of Tyrosine Isomers, Dalton Transactions 49, 31-34 (2020) 677. Yueyuan Li, Yaoguang Wang, Xuejing Liu, Rui Feng, Nuo Zhang, Dawei Fan, Caifeng Ding, Qin Wei*, Huangxian Ju, Bifunctional Pd-decorated polysulfide nanoparticle of Co9S8 supported on graphene oxide: A new and dfficient label-free immunosensor for amyloid β-protein detection, Sens. Actuat. B 304, 127413 (2020) 678. Chao Wang, Lei Liu, Xuejing Liu, Yu Chen, Dawei Fan, Yong Zhang, Xuan Kuan, Xu Sun, Huangxian Ju, Qin Wei*, Highly-sensitive electrochemiluminescence biosensor for NT-proBNP using MoS2@Cu2S as signal- enhancer and multinary nanocrystals loaded in mesopo-rous UiO-66-NH2 as novel luminophore, Sens. Actuat. B 307, 127619 (2020) 679. Weiwei Chen, Xiaobo Zhang, Juanjuan Li, Lizhen Chen, Ningning Wang, Siqi Yu, Guangming Li, Huangxian Ju*, Colorimetric detection of nucleic acids through triplex-hybridization chain reaction and DNA controlled growth of platinum nanoparticles on graphene oxide, Anal. Chem. 92(3), 2714-2721 (2020) 680. Jiawei Wang, Mingpan Cheng, Jielin Chen, Huangxian Ju, David Monchaud, Jean-Louis Mergny, Jun Zhou*, An oxidatively damaged G-quadruplex/hemin DNAzyme, Chem. Commun. 56, 1839-1842 (2020) 681. Lu Liu, Siqiao Li, Anwen Mao, Geyu Wang, Yiran Liu, Huangxian Ju, Lin Ding*, A localized molecular automaton for in situ visualization of proteins with specific chemical modifications, Chem. Sci. 11, 1665-1671 (2020) 682. Xin Liu, Chunzhu Bao, Xinrong Shao, Yong Zhang, Nuo Zhang, Xu Sun, Dawei Fan*, Qin Wei, Huangxian Ju, A procalcitonin photoelectrochemical immunosensor: NCQDs and Sb2S3 co-sensitized hydrangea-shaped WO3 as matrix through a layer-by-layer assembly, New J. Chem. 44, 2452-2458 (2020) 683. Cui Song, Xiaojian Li, Lihua Hu*, Tengfei Shi, Dan Wu, Hongmin Ma, Yong Zhang, Dawei Fan, Qin Wei*, Huangxian Ju, Quench-type electrochemiluminescence immunosensor based on resonance energy transfer from carbon nanotubes and Au-nanoparticles-enhanced g-C3N4 to CuO@polydopamine for procalcitonin detection, ACS Applied Mater. Interf. 12, 8006-8015 (2020)

684. Yi Man, Jinbo Liu, Jie Wu, Li Yin, Hua Pei, Qiang Wu, Qianfeng Xia*, Huangxian Ju*, An anchored monopodial DNA walker triggered by proximity hybridization for amplified amperometric biosensing of nucleic acid and protein, Anal. Chim. Acta 1107, 48-54 (2020) 685. Hui Ding, Lei Yang, Hongying Jia, Dawei Fan, Yong Zhang, Xu Sun, Qin Wei, Huangxian Ju*, Label-free electrochemical immunosensor based on palladium nanoparticles functionalized MoS2/NiCo heterostructures for sensitive procalcitonin detection, Sens. Actuat. B 312, 127980 (2020) 686. Chunzhu Bao, Xin Liu, Xinrong Shao, Xiang Ren, Yong Zhang, Xu Sun, Dawei Fan*, Qin Wei, Huangxian Ju*, Cardiac troponin I photoelectrochemical sensor: {Mo368} as electrode donor for Bi2S3 and Au co-sensitized FeOOH composite, Biosens. Bioelectron. 157, 112157 (2020) 687. Nan Feng, Junjie Hu, Qiulin Ma, Huangxian Ju*, Mass spectrometric biosensing: Multiplex enzymes assays using single mass probe and fluorous affinity chip, Biosens. Bioelectron. 157, 112159 (2020) 688. Jingxing Guo, Ying Liu, Yuanjiao Yang, Yumei Li, Ruiyong Wang, Huangxian Ju*, A filter supported surface- enhanced Raman scattering “nose” for point-of-care monitoring of gaseous metabolites of bacteria, Anal. Chem. 92, 5055-5063 (2020) 689. Pengyun Dang, Xuan Liu, Huangxian Ju, Jie Wu*, Intensive and persistent chemiluminescence system based on nano/bio-enzymes with local tandem catalysis and surface diffusion, Anal. Chem. 92, 5517-5523 (2020) 690. Yanrong Qian, Jinhui Feng, Rui Xu, Dawei Fan, Yu Du*, Xiang Ren*, Qin Wei, Huangxian Ju, Zinc and molybdenum codoped BiVO4 nanoarray for photoelectrochemical diethylstilbestrol analysis based on the dual-competitive system of MHCF@SiO2 NCs, ACS Applied Mater. Interf. 12, 16662-16669 (2020) 691. Zhongchao Jin, Xiaorong Zhu, Ningning Wang, Yafei Li*, Huangxian Ju, Jianping Lei*, Electroactive metal−organic frameworks as emitters for self-enhanced electrochemiluminescence in aqueous medium, Angew. Chem. Int. Ed. 10.1002/anie.202002713 accepted on March 20, 2020 692. Yuna Guo, Jing Tao, Yiran Li, Yimei Feng, Huangxian Ju, Zhongfu Wang, Lin Ding*, Quantitative localized analysis reveals distinct exosomal protein-specific glycosignatures: Implications in cancer cell subtyping, exosome biogenesis and function, J. Am. Chem. Soc. 142, 7404-7412 (2020) 693. Yuyi Li, Xiaobo Zhang, Yue Zhang, Yue Zhang, Yuling He, Ying Liu*, Huangxian Ju, Activatable photodynamic therapy with therapeutic effect prediction based on a self-correction upconversion nanoprobe, ACS Applied Mater. Interf. 10.1021/acsami.0c03432 accepted on April 12, 2020 694. Jing Tao, Xiaofei Yu, Yuna Guo, Guyu Wang, Huangxian Ju, Lin Ding*, Proximity enzymatic glyco-remodeling enables direct and highly efficient lipid raft imaging on live cells, Anal. Chem. 10.1021/acs.analchem.0c00810, accepted on April 16, 2020 695. Yueyuan Li, Lei Liu, Dawei Fan, Yaoguang Wang, Dan Wu, Yu Du, Xiang Ren*, Qin Wei*, Huanxian Ju, Enzyme-free colorimetric immunoassay for procalcitonin based on MgFe2O4 sacrificial probe with the Prussian blue production, Sens. Actuat. B Chem. https://doi.org/SNB128163 accepted on April 20, 2020 696. Yingfei Wang, Yuyi Li, Yue Zhang, Kewei Ren, Huangxian Ju, Ying Liu*, Express and sensitive detection of multiple miRNAs via DNA cascade reactors functionalized photonic crystal array, Sci. China-Chem. 10.1007/s11426-020-9712-y online in April, 2020 697. Tao Yan*, Xue Zhang, Xiang Ren, Yizhong Lu, Jinkai Li, Meng Sun*, Liangguo Yan, Qin Wei, Huangxian Ju, Fabrication of N-GQDs and AgBiS2 dual-sensitized ZIFs-derived hollow ZnxCo3-xO4 dodecahedron for sensitive photoelectrochemical aptasensing of ampicillin, Sens. Actuat. B Chem. SNB-S-20-00377 submitted on Jan 15, revision required on Feb. 23, sent on April 8, 2020 698. Yu Du, Jingwei Xue, Xu Sun, Dan Wu, Xuejing Liu, Huangxian Ju, Lei Yang, Qin Wei*, Oxygen vacancy- enhanced electrochemiluminescence sensing strategy using luminol thermally encapsulated in apoferritin as a transducer for biomarker immuoassy, Anal. Chem. ac-2020-01053v submitted on March 10, resubmission revision required on March 17, sent as ac-2020-01238u on March 21, 2020 699. Zhengqing He, Jie Wu, Bin Qiao, Hua Pei, Qianfeng Xia, Qiang Wu*, Huangxian Ju*, Target catalyzed assembly of pyrene labelled hairpins for exponentially amplified biosensing, ACS Sensors se-2020-00115s submitted on Jan 16, revision required on March 9, sent on April 16, 2020 700. Yue Zhang, Yue Zhang, Xiaobo Zhang, Yuyi Li, Yuling He, Ying Liu*, Huangxian Ju, Photo zipper locked DNA nanomachine with internal standard for precise miRNA imaging in living cells, Chem. Sci. SC-EDG-01-2020- 000394 submitted on Jan 21, major revision required on Feb. 18, 2020 701. Haiping Wu, Min Zhao, Jia Li, Xiaoyan Zhou, Tiantian Yang, Dezhang Zhao, Ping Liu, Huangxian Ju, Wei Cheng, Shijia Ding*, A novel long-lasting chemiluminescence system based on the Dox-ABEI chimeric magnetic DNA hydrogel for ultrasensitive immunoassay, ACS Applied Mater. Interf. am-2020-02664y submitted on Feb. 12, resubmission required on March 5, sent before Sept 1, 2020

702. Liu Qu, Lei Yang, Xiang Ren, Huan Wang, Dawei Fan, Kun Xu, Yueyuan Li*, Qin Wei, Huangxian Ju, A signal- off electrochemical sensing platform based on Fe3S4-Pd and pineal mesoporous bioactive glass for Procalcitonin detection, Sens. Actuat. B SNB-D-20-01480 submitted on March 9, revision required on April 14, 2020

Papers in review or preparation for publication 1. Dawei Fan, Xin Liu, Xinrong Shao, Yong Zhang, Nuo Zhang, Xueying Wang, Qin Wei*, Huangxian Ju, A cardiac troponin I photoelectrochemical immunosensor: NCQDs and BiOI co-sensitized flower-like SnO2 as matrix through layer-by-layer assembly, Microchim. Acta MIAC-D-20-00006 submitted on Jan 2, 2020 2. Farukh Mansoor, Shanaz Jahan, Huangxian Ju, Shamsa Kanwal*, Ultrasonic-assisted synthesis of leather-derived luminescent graphene quantum dots: Photo-catalytic reduction and switch on-off probe to detect nitro-explosives, Microchim. Acta MIAC-D-20-00243 submitted on Feb 7, 2020 3. Xiaofei Yu, Yiran Li, Yuna Guo, Peiwen Zhang, Guyu Wang, Lei Li, Huangxian Ju, Lin Ding*, Thermally triggered, cell-specific enzymatic glyco-editing: In situ regulation of lectin recognition and immune response on target cells, Chem. Sci. SC-EDG-03-2020-001322 submitted on March 4, 2020 4. Ke Lu, Siyu Shen, Ouyang Luo, Yue, Lu, Tianshu Shi, Jing Wu, Qi Cheng, Lei Fenag, Xiang Gao, Huangxian Ju, Wei Wang, Yi Cao, Huajian Teng, Feng Zhu, Jian Huang, Di Chen, Xiang Lu*, Chaojun Li*, Qing Jiang*, Bin Xue*, PP2Acα impacts acute liver injury by determining the fate of apoptosis/necroptosis in hepatocytes via ASK/JNK pathway, Hepatology HEP-20-0554 submitted on March 13, 2020 5. Jingwei Xue, Lei Yang, Yu Du, Yong Ren, Xiang Ren, Hongmin Ma, Dan Wu, Huangxian Ju, Qin Wei*, Yueyuan Li*, Quenching electrochemiluminescence sensing platform for biomarker immunoassay based on aggregation- induced enhanced nanocrystals as electrochemiluminescence emitters, Sens. Actuat. B SNB-D-20-02110 submitted on April 3, 2020 6. Tao Yan*, Yixuan Feng, Xiang Ren, Jinkai Li, Yizhong Lu, Meng Sun, Rui Feng, Liangguo Yan, Qin Wei*, Huangxian Ju, Fabrication of carbon dots hybrid MIL-68 (In) derived In2O3-In2S3 hollow tubular heterojunction and their exceptional self-powered PEC aptasensing properties for ampicillin detecting, J. Materiomics submitted on April 3, 2020 7. Yue Jia, Shanghua Liu, Yu Du, Lei Yang, Lei Liu, Xuejing Liu, Xiang Ren*, Qin Wei*, Huangxian Ju, Intramolecular electrochemiluminescence of polypeptide-biomineralized gold nanoclusters for targeted detection of biomarkers, Anal. Chem. ac-2020-01519a submitted on April 9, 2020 8. Siqiao Li, Anwen Mao, Xiaojian Wang, Lu Liu, Huangxian Ju, Lin Ding*, Localized glyco-editing on live cells reveals protein-specific glycan functions, Angew. Chem. Int. Ed. 202005219 submitted on April 10, 2020 9. Si Zhang, Hejie Zheng, Xiaoqiang Liu*, Yanmei Zhou, Huangxian Ju*, Oxygen vacancies enhanced photoelectrochemical aptasensing of 2,3',5,5'–tetrachlorobiphenyl amplified with Ag3VO4 nanoparticle - TiO2 nanotube array heterostructure, Biosens. Bioelectron. BIOS-D-20-01278 submitted on April 14, 2020 10. Yueyuan Li, Yu Du, Lei Liu, Xuejing Liu, Nuo Zhang, Xiang Ren, Xueying Wang, Huan Wang*, Qin Wei, Huanxian Ju, Electrochemical and colorimetric dual-mode immunoassay for procalcitonin based on FeOOH-Au adsorbed methylene blue as a double-signal indicator, Sens. Actuat. B SNB-D-20-02478 submitted on April 23, 2020 11. Yue Zhang, Weiwei Chen, Yue Zhang, Xiaobo Zhang, Ying Liu*, Huangxian Ju*, Near-infrared photo-switched microRNA amplifier for precise photodynamic therapy of early-stage cancers, Angew. Chem. Int. Ed. 202006002 submitted on April 25, 2020 12. Xiaojian Li, Yu Du, Peng Xu, Yueyun Li, Xiang Ren, Hongmin Ma, Huan Wang, Qin Wei*, Huangxian Ju, Signal- off electrochemiluminescence immunosensor based on Mn-eumelanin coordination nanoparticles quenching PtCo- CuFe2O4-reduced graphene oxide enhanced luminol, Biosens. Bioelectron. BIOS-D-20-0 submitted on April 29, 2020 13. Xiaobo Zhang, Weiwei Chen, Rong He, Xiaoyu Xie, Haibo Ma, Ying Liu*, Huangxian Ju*, Relay station strategy for modulation of long-distance upconversion luminescence resonance energy transfer, PNAS 201915810 submitted on May 2, 2020 14. Jielin Chen, Jiawei Wang, Stephanie C. C. van der Lubbe, Mingpan Cheng, Dehui Qiu, David Monchaud, Jean- Louis Mergny, Célia Fonseca Guerra*, Jun Zhou*, Huangxian Ju*, A push-pull mechanism helps designing highly competent G-quadruplex-DNA catalysts PNAS 201915810 submitted on May 9, 2020

15. Bingdong Yan, Xiaoru Zhao, Yi Zhuang, Delun Chen, Yang Cao, Jinchun Tu*, Huangxian Ju*, Qiang Wu*, A efficient electron transfer photoelectrochemical biosensing platform constructed with metal-organic- semiconductor composites, Anal. Chim. Acta ACA-20-874 submitted on March 18, 2020

16. Huangxian Ju*, In situ analysis of cellular functional molecules Sci. China-Chem. submitted on Feb 26, 2020

1. Kumarasamy Jayakumar, María Belén Camarada, Huangxian Ju*, Selective atomic confined role of oxygen molecules as active sites for electrochemical conversion of CO2 into C2 hydrocarbons Nat. Energy submitted on Feb 26, 2019 2. Kumarasamy Jayakumar, Huangxian Ju*, Hierarchical bimetallic phosphide nano sheet enables highly efficient electrochemical CO2 reduction, Adv. Mater. submitted on March 5, 2019 3. Lizhen Chen, Naixiang Wang, Anneng Yang, Jie Wu, Feng Yan*, Huangxian Ju*, Organic electrochemical transistor for sensing sialic acid in serum samples, Sens. Actuat. B submitted on Oct. 20, 2019 4. Wenjuan Zhu, Xiang Ren, Dawei Fan, Xuan Kuang, Xu Sun, Yong Zhang, Hongmin Ma, Qin Wei*, Huangxian Ju, Remarkable quenching of Cys-CdS QDs electrochemiluminescence by Cu-apatite for insulin assay Biosens. Bioelectron. BIOS-D-19-03829 submitted on Nov 18, 2019

Tingyuan Lang, Jianwei Ge, Zhiqi Zhang, Jiangfeng Qiu, Xiaobo Zhang, Yue Zhang, Fang Wang, Jintong Liu, Lei Zhou, Huangxian Ju*, Shijia Ding*, Luteolin inhibits cancer stemness by targeting Hippo/YAP signalling pathway, submitted on April 18, 2018

1. 周俊 DNAzyme Chem. Rev. submitted in Sept, 2019 1. Lan Li, Kaijia Zhang, Tiankuo Wang, Jing Jin, Huangxian Ju, Wei Wang, Xiang Gao, Bin Xue, Yi Cao, Xingsong Wang; Qing Jiang*, A biomimetic supramolcular-polymer double network hydrogel for cartilage regeneration, Acta Biomater. AB-19-1681 submitted on July 19, 2019 2. Lan Li, Jianping Shi, Kaiwei Ma, Kaijia Zhang, Jing Jin, Fei Yu, Liya Zhu, Huangxian Ju, Wei Wang, Xiang Gao, Yi Cao*, Xingsong Wang*, Qing Jiang*, In situ repair of large segmental bone defects using direct 3D bioprinting technology in a swine model, Sci. Adv. aay1202 submitted on May 22, 2019

英文稿件作为专刊发表在《SCIENCE CHINA Chemistry》期刊上 2020 年 5 月，在《中国科学：化学》出版庆祝南京大学化学化工学院百年院庆的专刊，拟出版 15-20 篇英文稿件，其中 8 篇为特约综述文章。鉴于您在学术领域的深厚造诣，以及对我院科研工作的重要贡献，经黎书华院长和朱成建书记共同推荐，诚邀您撰写一篇综述文章，在该专刊发表。以下是一些细节： 1. 稿件用英文撰写。Perspective 也可以 1-2 个图 3 页 2. 截稿时间是 12 月 31 日，以便在明年 5 月院庆之际出版。截稿时间是 12 月 31 日，影响因子是 6.1，英文刊物《SCIENCE CHINA Chemistry》只接受 Article 和 Communications 的投稿，Review 采取邀请审核制，不接受自由投稿， dedication：Dedicated to the 100th anniversary of the School of Chemistry and Chemical Engineering, Nanjing University 685. Jingxing Guo, Yawei Wang, Yunqiang Bian, Xiaobo Zhang, Dehui Qiu, Qianmei Lin, Jean-Louis Mergny, Huangxian Ju*, Jun Zhou*, Conveniently probing the subtle structural distinction of G-quadruplexes coordinated with different cations by surface-enhanced Raman scattering, J. Raman Spectr. JRS-19-0327 submitted on Sept 28, major revision required on Nov 10, 2019