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Table of Contents (PDF) January 4, 2011 u vol. 108 u no. 1 u 1–434 Cover image: Pictured is a single layer of mouse embryonic fibroblasts, with the mesh-like actin cytoskeleton shown in blue and the Abi1 protein, an actin cytoskeleton adaptor mol- ecule, shown in red. Regions of cell-to-cell contact are enriched with Abi1 protein, giving the fibroblasts a cobblestone-like appearance. Colleen Ring et al. find that Abi proteins regulate the actin cytoskeletal dynamics downstream of cell adhesion and matrix receptors, such as the α4 integrin. See the article by Ring et al. on pages 149–154. Image courtesy of Colleen Ring. From the Cover 149 Regulating cellular morphogenesis 109 Refining classical protein models 114 Revealing myosin hinges 120 Stretch activation in insect muscles 250 Neandertal mating behavior 5 Essential “ankle” in the myosin lever arm Olena Pylypenko and Anne M. Houdusse Contents See companion article on page 114 7 Steric blocking mechanism explains stretch activation in insect flight muscle THIS WEEK IN PNAS Kenneth C. Holmes See companion article on page 120 1 In This Issue PROFILE LETTERS (ONLINE ONLY) 9 Profile of Stephen P. Goff E1 Mild oxidative stress activates Nrf2 in astrocytes, which Greg Williams contributes to neuroprotective ischemic preconditioning See Inaugural Article on page 4071 in issue 11 Karen F. Bell, Bashayer Al-Mubarak, Jill H. Fowler, Paul S. of volume 106 Baxter, Kunal Gupta, Tadayuki Tsujita, Sudhir Chowdhry, Rickie Patani, Siddharthan Chandran, Karen Horsburgh, John D. Hayes, and Giles E. Hardingham E3 Reply to Bell et al.: Nrf2-dependent and -independent INAUGURAL ARTICLE mechanisms of astrocytic neuroprotection Renée E. Haskew-Layton, Thong C. Ma, and Rajiv R. Ratan 12 Completely phased genome sequencing through chromosome sorting Hong Yang, Xi Chen, and Wing Hung Wong COMMENTARIES 3 Ramachandran redux PHYSICAL SCIENCES Zhengshuang Shi and Neville R. Kallenbach See companion article on page 109 APPLIED MATHEMATICS 197 A network model for plant–pollinator community assembly Colin Campbell, Suann Yang, Réka Albert, Free online through the PNAS open access option. and Katriona Shea PNAS u January 4, 2011 u vol. 108 u no. 1 u iii–viii Downloaded by guest on October 2, 2021 APPLIED PHYSICAL SCIENCES 421 Children with autism are neither systematic nor 18 Quantitative and empirical demonstration of the optimal foragers Matthew effect in a study of career longevity Elizabeth Pellicano, Alastair D. Smith, Filipe Cristino, Alexander M. Petersen, Woo-Sung Jung, Bruce M. Hood, Josie Briscoe, and Iain D. Gilchrist Jae-Suk Yang, and H. Eugene Stanley 24 Pressure-induced superconductivity in topological SOCIAL SCIENCES parent compound Bi2Te3 J. L. Zhang, S. J. Zhang, H. M. Weng, W. Zhang, L. X. Yang, 18 Quantitative and empirical demonstration of the Q. Q. Liu, S. M. Feng, X. C. Wang, R. C. Yu, L. Z. Cao, Matthew effect in a study of career longevity L. Wang, W. G. Yang, H. Z. Liu, W. Y. Zhao, Alexander M. Petersen, Woo-Sung Jung, S. C. Zhang, X. Dai, Z. Fang, and C. Q. Jin Jae-Suk Yang, and H. Eugene Stanley 427 Derivation of Ca2+ signals from puff properties reveals that pathway function is robust against SUSTAINABILITY SCIENCE cell variability but sensitive for control Kevin Thurley and Martin Falcke 203 Socioeconomic legacy yields an invasion debt Franz Essl, Stefan Dullinger, Wolfgang Rabitsch, š CHEMISTRY Philip E. Hulme, Karl Hülber, Vojtech Jaro ík, Ingrid Kleinbauer, Fridolin Krausmann, Ingolf Kühn, 29 Photoinduced electron transfer from semiconductor Wolfgang Nentwig, Montserrat Vilà, Piero Genovesi, quantum dots to metal oxide nanoparticles Francesca Gherardi, Marie-Laure Desprez-Loustau, Kevin Tvrdy, Pavel A. Frantsuzov, and Prashant V. Kamat Alain Roques, and Petr Pyšek 61 Mechanism of inactivation of influenza viruses by immobilized hydrophobic polycations Bryan B. Hsu, Sze Yinn Wong, Paula T. Hammond, Jianzhu Chen, and Alexander M. Klibanov BIOLOGICAL SCIENCES ENGINEERING APPLIED BIOLOGICAL SCIENCES 35 Quantifying the biophysical characteristics of Plasmodium-falciparum-parasitized red blood 61 Mechanism of inactivation of influenza viruses by cells in microcirculation immobilized hydrophobic polycations D. A. Fedosov, B. Caswell, S. Suresh, and G. E. Karniadakis Bryan B. Hsu, Sze Yinn Wong, Paula T. Hammond, Jianzhu Chen, and Alexander M. Klibanov 67 Active scaffolds for on-demand drug and cell delivery Xuanhe Zhao, Jaeyun Kim, Christine A. Cezar, 67 Active scaffolds for on-demand drug and cell delivery Nathaniel Huebsch, Kangwon Lee, Kamal Bouhadir, Xuanhe Zhao, Jaeyun Kim, Christine A. Cezar, and David J. Mooney Nathaniel Huebsch, Kangwon Lee, Kamal Bouhadir, and David J. Mooney GEOPHYSICS 40 Nanodiamonds do not provide unique evidence for a Younger Dryas impact BIOCHEMISTRY H. Tian, D. Schryvers, and Ph. Claeys 73 Two RNA subunits and POT1a are components of Arabidopsis telomerase PHYSICS Catherine Cifuentes-Rojas, Kalpana Kannan, Lin Tseng, 45 Condensates in quantum chromodynamics and Dorothy E. Shippen and the cosmological constant Stanley J. Brodsky and Robert Shrock 79 pH-sensitivity of the ribosomal peptidyl transfer reaction dependent on the identity of the 51 Ferromagnetism in the upper branch of the Feshbach A-site aminoacyl-tRNA resonance and the hard-sphere Fermi gas Magnus Johansson, Ka-Weng Ieong, Stefan Trobro, Soon-Yong Chang, Mohit Randeria, and Nandini Trivedi Peter Strazewski, Johan Åqvist, Michael Y. Pavlov, and Måns Ehrenberg STATISTICS 12 Completely phased genome sequencing through 85 Myogenic transcriptional activation of MyoD mediated chromosome sorting by replication-independent histone deposition Hong Yang, Xi Chen, and Wing Hung Wong Jae-Hyun Yang, Yunkyoung Song, Ja-Hwan Seol, Jin Young Park, Yong-Jin Yang, Jeung-Whan Han, Hong-Duk Youn, and Eun-Jung Cho SOCIAL SCIENCES 91 Dual role of the receptor Tom20 in specificity and efficiency of protein import into mitochondria Hayashi Yamamoto, Nobuka Itoh, Shin Kawano, PSYCHOLOGICAL AND COGNITIVE SCIENCES Yoh-ichi Yatsukawa, Takaki Momose, Tadashi Makio, 55 How instructed knowledge modulates the neural Mayumi Matsunaga, Mihoko Yokota, Masatoshi Esaki, systems of reward learning Toshihiro Shodai, Daisuke Kohda, Alyson E. Aiken Hobbs, Jian Li, Mauricio R. Delgado, and Elizabeth A. Phelps Robert E. Jensen, and Toshiya Endo iv u www.pnas.org Downloaded by guest on October 2, 2021 97 Evolution in a family of chelatases facilitated by the DEVELOPMENTAL BIOLOGY introduction of active site asymmetry and protein 155 Reiterative AP2a activity controls sequential steps oligomerization in the neural crest gene regulatory network Célia V. Romão, Dimitrios Ladakis, Susana A. L. Lobo, Noémie de Crozé, Frédérique Maczkowiak, Maria A. Carrondo, Amanda A. Brindley, Evelyne and Anne H. Monsoro-Burq Deery, Pedro M. Matias, Richard W. Pickersgill, Lígia M. Saraiva, and Martin J. Warren 161 Transient retinoic acid signaling confers anterior- 103 Z-DNA-forming silencer in the first exon regulates posterior polarity to the inner ear human ADAM-12 gene expression Jinwoong Bok, Steven Raft, Kyoung-Ah Kong, Bimal K. Ray, Srijita Dhar, Arvind Shakya, Soo Kyung Koo, Ursula C. Dräger, and Doris K. Wu and Alpana Ray 167 Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning BIOPHYSICS AND COMPUTATIONAL BIOLOGY Jonah Cool, Tony J. DeFalco, and Blanche Capel 109 Redrawing the Ramachandran plot after inclusion of 173 Model of pediatric pituitary hormone deficiency hydrogen-bonding constraints separates the endocrine and neural functions Lauren L. Porter and George D. Rose of the LHX3 transcription factor in vivo See Commentary on page 3 Stephanie C. Colvin, Raleigh E. Malik, Aaron D. Showalter, Kyle W. Sloop, and Simon J. Rhodes 114 Visualizing key hinges and a potential major source of compliance in the lever arm of myosin Jerry H. Brown, V. S. Senthil Kumar, Elizabeth 179 Mouse telomerase reverse transcriptase (mTert) O’Neall-Hennessey, Ludmila Reshetnikova, expression marks slowly cycling intestinal stem cells Howard Robinson, Michelle Nguyen-McCarty, Robert K. Montgomery, Diana L. Carlone, Camilla A. Andrew G. Szent-Györgyi, and Carolyn Cohen Richmond, Loredana Farilla, Mariette E. G. Kranendonk, See Commentary on page 5 Daniel E. Henderson, Nana Yaa Baffour-Awuah, Dana M. Ambruzs, Laura K. Fogli, Selma Algra, 120 X-ray diffraction evidence for myosin-troponin and David T. Breault connections and tropomyosin movement during stretch activation of insect flight muscle 185 Neurogenin3 inhibits proliferation in endocrine Robert J. Perz-Edwards, Thomas C. Irving, Bruce A. J. progenitors by inducing Cdkn1a Baumann, David Gore, Daniel C. Hutchinson, Uroš Takeshi Miyatsuka, Yasuhiro Kosaka, Hail Kim, Kržic, Rebecca L. Porter, Andrew B. Ward, and Michael S. German and Michael K. Reedy See Commentary on page 7 191 Parathyroid hormone/parathyroid hormone-related protein receptor signaling is required for maintenance 126 Experimental support for the evolution of symmetric of the growth plate in postnatal life protein architecture from a simple peptide motif Takao Hirai, Andrei S. Chagin, Tatsuya Kobayashi, Jihun Lee and Michael Blaber Susan Mackem, and Henry M. Kronenberg CELL BIOLOGY 131 Lamin A variants that cause striated muscle disease are ECOLOGY defective in anchoring transmembrane actin-associated 197 A network model for plant–pollinator nuclear lines for nuclear movement community assembly Eric S. Folker, Cecilia Östlund, G. W. Gant Luxton, Colin Campbell, Suann Yang, Réka Albert, Howard J. Worman, and Gregg G. Gundersen and Katriona Shea 137 Intracellular
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