The Historical Origin of the Chinese Taoist and Tai Chi
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Genetic Variants and Clinical Significance of Pediatric Acute Lymphoblastic Leukemia
296 Original Article Page 1 of 11 Genetic variants and clinical significance of pediatric acute lymphoblastic leukemia Hong-Hong Zhang1,2#, Hong-Sheng Wang1,2#, Xiao-Wen Qian1,2, Cui-Qing Fan2, Jun Li1,2, Hui Miao1,2, Xiao-Hua Zhu1,2, Yi Yu1,2, Jian-Hua Meng1,2, Ping Cao1,2, Jun Le1,2, Jun-Ye Jiang1,2, Wen-Jing Jiang1,2, Ping Wang1,2, Xiao-Wen Zhai1,2 1Department of Hematology and Oncology, 2Department of Pediatrics, Children’s Hospital of Fudan University, Shanghai 201102, China Contributions: (I) Conception and design: HH Zhang, HS Wang; (II) Administrative support: XW Zhai; (III) Provision of study materials or patients: XW Qian, J Li, WJ Jiang, P Wang; (IV) Collection and assembly of data: H Miao, XH Zhu, JY Jiang, CQ Fan, J Le; (V) Data analysis and interpretation: Y Yu, JH Meng, P Cao, HH Zhang, HS Wang; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. #These authors contributed equally to this work. Correspondence to: Xiao-Wen Zhai. Department of Hematology and Oncology, Children’s Hospital of Fudan University, 399 Wanyuan Road, Shanghai 201102, China. Email: [email protected]. Background: Acute lymphoblastic leukemia (ALL), the most common childhood malignancy, is characterized by molecular aberrations. Recently, genetic profiling has been fully investigated on ALL; however, the interaction between its genetic alterations and clinical features is still unclear. Therefore, we investigated the effects of genetic variants on ALL phenotypes and clinical outcomes. Methods: Targeted exome sequencing technology was used to detect molecular profiling of 140 Chinese pediatric patients with ALL. -
Ras Pathway Mutation Feature in the Same Individuals at Diagnosis and Relapse of Childhood Acute Lymphoblastic Leukemia
12 Original Article Ras pathway mutation feature in the same individuals at diagnosis and relapse of childhood acute lymphoblastic leukemia Hong-Hong Zhang1#, Hong-Sheng Wang1#, Xiao-Wen Qian1, Xiao-Hua Zhu1, Hui Miao1, Yi Yu1, Jian-Hua Meng1, Jun Le1, Jun-Ye Jiang1, Ping Cao1, Wen-Jing Jiang1, Ping Wang1, Yang Fu1, Jun Li1, Mao-Xiang Qian2, Xiao-Wen Zhai1 1Department of Hematology, 2Institute of Pediatrics, Children’s hospital of Fudan University, Shanghai 201102, China Contributions: (I) Conception and design: HH Zhang, HS Wang; (II) Administrative support: XW Zhai; (III) Provision of study materials or patients: XW Qian, XH Zhu, H Miao, Y Yu; (IV) Collection and assembly of data: JH Meng, J Le, Y Fu, JY Jiang, WJ Jiang, MX Qian; (V) Data analysis and interpretation: P Cao, P Wang, J Li, HH Zhang, HS Wang, XW Zhai; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. #These authors contributed equally to this work. Correspondence to: Xiao-Wen Zhai. Department of Hematology, Children’s hospital of Fudan University, No. 399 Wanyuan Road, Shanghai 201102, China. Email: [email protected]. Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children, while relapse and refractory ALL remains a leading cause of death in children. However, paired ALL samples of initial diagnosis and relapse subjected to next-generation sequencing (NGS) could construct clonal lineage changes, and help to explore the key issues in the evolutionary process of tumor clones. Therefore, we aim to analyze gene alterations during the initial diagnosis and relapse of ALL patients and to explore the underlying mechanism. -
Tongguang Zhai ————————————————————————————————
Tongguang Zhai ———————————————————————————————— Tel no: (859) 257-4958 (office) Postal address: 163B F. Paul Anderson Tower (859) 396-0924 (home) Department of Chemical & Materials Engineering E-mail: [email protected] University of Kentucky Lexington, Kentucky 40506, USA Academic Degrees D.Phil. (Ph.D.), 9/1994 B.Sc., 7/1983 University of Oxford, England University of Science and Technology Beijing, China Research Interests • Fatigue life prediction: identification of fatigue weak-link density and strength distribution, quantification of fatigue crack initiation and resistance to fatigue crack growth due to crack deflection at grain boundaries, • Optimum alloy design through micro- and macro-texture control, • Failure analysis, Materials characterisation, processing and modelling, etc. Education and Career 6/2007—Present Associate Professor Department of Chemical and Materials Engineering University of Kentucky, Lexington, KY 40506-0046, USA 8/2001—5/2007 Assistant Professor Department of Chemical and Materials Engineering University of Kentucky, Lexington, KY 40506-0046, USA 8/2000—6/2001 Postdoctoral Research Associate Light metals research center, Department of Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, USA 1/1995—7/2000 Research fellow Department of Materials, University of Oxford 10/1994—12/1994 Research Assistant Fraunhofer Institute for NDT (IzfP), University Building 37, 66123 Saarbrueken, Germany 10/1991—9/1994 D. Phil. student Department of Materials, University of Oxford Academic Awards and Honours ● NSF CAREER AWARD: 7/2007-6/2012 ● Visiting Professorship: University of Hong Kong (June, 2009), Sichuan University (June, 2005). ● Excellent Teacher Award by College of Engineering, University of Kentucky, 2002/2003. ● Buehler Technical Merit Paper Award, 4/1994, jointly by International Metallography Society and Materials Characterisation, Paper 48) in the publication list. -
Deanxit Relieves Symptoms in a Patient with Jackhammer Esophagus: a Case Report
Submit a Manuscript: http://www.f6publishing.com World J Gastrointest Endosc 2017 December 16; 9(12): 590-593 DOI: 10.4253/wjge.v9.i12.590 ISSN 1948-5190 (online) CASE REPORT Deanxit relieves symptoms in a patient with jackhammer esophagus: A case report Jin-Ying Li, Wen-Huan Zhang, Chun-Ling Huang, Dang Huang, Guo-Wen Zuo, Lie-Xin Liang Jin-Ying Li, Wen-Huan Zhang, Chun-Ling Huang, Dang Huang, Revised: October 25, 2017 Guo-Wen Zuo, Lie-Xin Liang, Department of Gastroenterology, Accepted: November 11, 2017 People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning Article in press: November 11, 2017 530021, Guangxi Zhuang Autonomous Region, China Published online: December 16, 2017 ORCID number: Jin-Ying Li (0000-0002-4101-1553); Wen- Huan Zhang (0000-0002-4362-7378); Chun-Ling Huang (0000- 0001-5512-173X); Dang Huang (0000-0003-2447-8319); Guo- Wen Zuo (0000-0002-3100-937X); Lie-Xin Liang (0000- Abstract 0002-2029-5059). Jackhammer (hypercontractile) esophagus presents with dysphagia and chest pain. Current treatments are Author contributions: Zuo GW designed the report; Li JY limited. We describe a 60-year-old man who presented collected references and prepared the manuscript, with the help with dysphagia, chest pain and heartburn for a period of Huang D; Zhang WH and Huang CL provided the figures; Zuo of 1 year. His workup showed Barrett’s esophagus on GW and Liang LX supervised the preparation of the manuscript. endoscopy and high-resolution manometry demonstrated Informed consent statement: The patient involved in this jackhammer esophagus with esophagogastric junction study gave his written informed consent authorizing use and outflow obstruction. -
Zhou Dynasty 1046 - 256 BC
Quinn Steven Professor Mustafa Tuna April 28, 2017 SES 373 Recipes through the Dynasties: How Chinese Food and Food Culture Changed over Time For this proJect, I selected various Dynasties and time periods throughout Chinese history that represent the most significant changes to Chinese cuisine due to socioeconomic, political, industrial, or cultural impacts and globalization. I selected the Zhou Dynasty, the Mongol Empire, the Song Dynasty, the Yuan Dynasty, the Ming Dynasty, the Qing Dynasty, and the Cultural Revolution because each has aspects that were completely uniQue during their time, but contributed to modern Chinese cuisine in a fundamental way. For each time period, I provided a brief introduction to the period, one or more recipes from that time period, and a brief narrative piece, or two in the case of the Song Dynasty, to give insight into how food may have appeared during that time period. Zhou Dynasty 1046 - 256 BC Period: The Zhou Dynasty, founded by the Ji family in 1046, was the era of bronze-making and also was the beginning of formal, ritualized dining in China with traditions, special cuisines and dishes, etiQuette, and hierarchy. In the kitchen, there was a hierarchy: the chief cook, the internal cooks, the external cooks, assistants, nutritionists, and wine officers, who altogether made up a cooking staff of more than 2,300 individuals. The chief cook was in charge of organizing the kitchen, food, and drinks for the Emperor, Empress, and crown prince, the internal cooks cooked their meals, and the assistants were responsible for food preparation, serving, and maintaining cooking fires. -
Negotiation Philosophy in Chinese Characters
6 Ancient Wisdom for the Modern Negotiator: What Chinese Characters Have to Offer Negotiation Pedagogy Andrew Wei-Min Lee* Editors’ Note: In a project that from its inception has been devoted to second generation updates, it is instructive nonetheless to realize how much we have to learn from the past. We believe Lee’s chapter on Chinese characters and their implications for negotiation is groundbreaking. With luck, it will prove to be a harbinger of a whole variety of new ways of looking at our field that will emerge from our next round of discussion. Introduction To the non-Chinese speaker, Chinese characters can look like a cha- otic mess of dots, lines and circles. It is said that Chinese is the most difficult language in the world to learn, and since there is no alpha- bet, the struggling student has no choice but to learn every single Chinese character by sheer force of memory – and there are tens of thousands! I suggest a different perspective. While Chinese is perhaps not the easiest language to learn, there is a very definite logic and sys- tem to the formation of Chinese characters. Some of these characters date back almost eight thousand years – and embedded in their make-up is an extraordinary amount of cultural history and wisdom. * Andrew Wei-Min Lee is founder and president of the Leading Negotiation Institute, whose mission is to promote negotiation pedagogy in China. He also teaches negotiation at Peking University Law School. His email address is an- [email protected]. This article draws primarily upon the work of Feng Ying Yu, who has spent over three hundred hours poring over ancient Chinese texts to analyze and decipher the make-up of modern Chinese characters. -
The Analects of Confucius
The analecTs of confucius An Online Teaching Translation 2015 (Version 2.21) R. Eno © 2003, 2012, 2015 Robert Eno This online translation is made freely available for use in not for profit educational settings and for personal use. For other purposes, apart from fair use, copyright is not waived. Open access to this translation is provided, without charge, at http://hdl.handle.net/2022/23420 Also available as open access translations of the Four Books Mencius: An Online Teaching Translation http://hdl.handle.net/2022/23421 Mencius: Translation, Notes, and Commentary http://hdl.handle.net/2022/23423 The Great Learning and The Doctrine of the Mean: An Online Teaching Translation http://hdl.handle.net/2022/23422 The Great Learning and The Doctrine of the Mean: Translation, Notes, and Commentary http://hdl.handle.net/2022/23424 CONTENTS INTRODUCTION i MAPS x BOOK I 1 BOOK II 5 BOOK III 9 BOOK IV 14 BOOK V 18 BOOK VI 24 BOOK VII 30 BOOK VIII 36 BOOK IX 40 BOOK X 46 BOOK XI 52 BOOK XII 59 BOOK XIII 66 BOOK XIV 73 BOOK XV 82 BOOK XVI 89 BOOK XVII 94 BOOK XVIII 100 BOOK XIX 104 BOOK XX 109 Appendix 1: Major Disciples 112 Appendix 2: Glossary 116 Appendix 3: Analysis of Book VIII 122 Appendix 4: Manuscript Evidence 131 About the title page The title page illustration reproduces a leaf from a medieval hand copy of the Analects, dated 890 CE, recovered from an archaeological dig at Dunhuang, in the Western desert regions of China. The manuscript has been determined to be a school boy’s hand copy, complete with errors, and it reproduces not only the text (which appears in large characters), but also an early commentary (small, double-column characters). -
Official Colours of Chinese Regimes: a Panchronic Philological Study with Historical Accounts of China
TRAMES, 2012, 16(66/61), 3, 237–285 OFFICIAL COLOURS OF CHINESE REGIMES: A PANCHRONIC PHILOLOGICAL STUDY WITH HISTORICAL ACCOUNTS OF CHINA Jingyi Gao Institute of the Estonian Language, University of Tartu, and Tallinn University Abstract. The paper reports a panchronic philological study on the official colours of Chinese regimes. The historical accounts of the Chinese regimes are introduced. The official colours are summarised with philological references of archaic texts. Remarkably, it has been suggested that the official colours of the most ancient regimes should be the three primitive colours: (1) white-yellow, (2) black-grue yellow, and (3) red-yellow, instead of the simple colours. There were inconsistent historical records on the official colours of the most ancient regimes because the composite colour categories had been split. It has solved the historical problem with the linguistic theory of composite colour categories. Besides, it is concluded how the official colours were determined: At first, the official colour might be naturally determined according to the substance of the ruling population. There might be three groups of people in the Far East. (1) The developed hunter gatherers with livestock preferred the white-yellow colour of milk. (2) The farmers preferred the red-yellow colour of sun and fire. (3) The herders preferred the black-grue-yellow colour of water bodies. Later, after the Han-Chinese consolidation, the official colour could be politically determined according to the main property of the five elements in Sino-metaphysics. The red colour has been predominate in China for many reasons. Keywords: colour symbolism, official colours, national colours, five elements, philology, Chinese history, Chinese language, etymology, basic colour terms DOI: 10.3176/tr.2012.3.03 1. -
Chen Gui and Other Works Attributed to Empress Wu Zetian
chen gui denis twitchett Chen gui and Other Works Attributed to Empress Wu Zetian ome quarter-century ago, studies by Antonino Forte and Richard S Guisso greatly advanced our understanding of the ways in which the empress Wu Zetian ࣳঞ֚ made deliberate and sophisticated use of Buddhist materials both before and after declaring herself ruler of a new Zhou ࡌʳdynasty in 690, in particular the text of Dayun jing Օႆᆖ in establishing her claim to be a legitimate sovereign.1 However, little attention has ever been given to the numerous political writings that had earlier been compiled in her name. These show that for some years before the demise of her husband emperor Gaozong in 683, she had been at considerable pains to establish her credentials as a potential ruler in more conventional terms, and had commissioned the writing of a large series of political writings designed to provide the ideologi- cal basis for both a new style of “Confucian” imperial rule and a new type of minister. All save two of these works were long ago lost in China, where none of her writings seems to have survived the Song, and most may not have survived the Tang. We are fortunate enough to possess that titled complete with its commentary, and also a fragmentary Chen gui copy of the work on music commissioned in her name, Yue shu yaolu ᑗ ᙕ,2 only thanks to their preservation in Japan. They had been ac- quired by an embassy to China, almost certainly that of 702–704, led టԳ (see the concluding section of thisضby Awata no ason Mahito ொ article) to the court of empress Wu, who was at that time sovereign of 1 See Antonino Forte, Political Propaganda and Ideology in China at the End of the Seventh Century (Naples: Istituto Universitario Orientale,1976); R. -
African Logistics Agents and Middlemen As Cultural Brokers in Guangzhou, In: Journal of Current Chinese Affairs, 44, 4, 117–144
Journal of Current Chinese Affairs China aktuell Topical Issue: Foreign Lives in a Globalising City: Africans in Guangzhou Guest Editor: Gordon Mathews Mathews, Gordon (2015), African Logistics Agents and Middlemen as Cultural Brokers in Guangzhou, in: Journal of Current Chinese Affairs, 44, 4, 117–144. URN: http://nbn-resolving.org/urn/resolver.pl?urn:nbn:de:gbv:18-4-9163 ISSN: 1868-4874 (online), ISSN: 1868-1026 (print) The online version of this article and the other articles can be found at: <www.CurrentChineseAffairs.org> Published by GIGA German Institute of Global and Area Studies, Institute of Asian Studies and Hamburg University Press. The Journal of Current Chinese Affairs is an Open Access publication. It may be read, copied and distributed free of charge according to the conditions of the Creative Commons Attribution-No Derivative Works 3.0 License. To subscribe to the print edition: <[email protected]> For an e-mail alert please register at: <www.CurrentChineseAffairs.org> The Journal of Current Chinese Affairs is part of the GIGA Journal Family, which also includes Africa Spectrum, Journal of Current Southeast Asian Affairs and Journal of Politics in Latin America: <www.giga-journal-family.org>. Journal of Current Chinese Affairs 4/2015: 117–144 African Logistics Agents and Middlemen as Cultural Brokers in Guangzhou Gordon MATHEWS Abstract: This article begins by asking how African traders learn to adjust to the foreign world of Guangzhou, China, and suggests that African logistics agents and middlemen serve as cultural brokers for these traders. After defining “cultural broker” and discussing why these brokers are not usually Chinese, it explores this role as played by ten logistics agents/middlemen from Kenya, Nigeria, Ghana and the Democratic Republic of the Congo. -
Learning Chinese
Learning Chinese Chinese is the native language of over a billion speakers, more Language Family people than any other language. It is spoken in China, Singapore, Sino-Tibetan Malaysia, and in many overseas Chinese communities. Dialect 4UBOEBSE.BOEBSJOJTCBTFEPO/PSUIFSO Writing Systems: Chinese dialects. Standard Mandarin is Simplified, Traditional, and Pinyin the language of business, education, and the media in all regions of China, and is tSimplified Chinese (e.g. 汉语) characters are widely used in the People’s widely understood in almost every corner Republic of China. They are based on and share most of their characters of the Chinese-speaking world. with traditional Chinese characters. t Traditional Chinese (e.g. 漢語) characters are in widespread use in Your Learning Options Taiwan, Hong Kong, Macau, and in many overseas Chinese communities. t3PTFUUB4UPOFPGGFSTZPVUIFDIPJDFPG Knowledge of traditional characters will also allow you to recognize many Simplified or Traditional characters characters in classical Chinese texts. for your course. Simplified Traditional tPinyin (e.g. hàn yǔ) is a method of writing Chinese using the Roman alphabet. Pinyin is a transliteration of characters into the Roman script and is used for teaching the language phonetically and for typing Chinese. t3PTFUUB4UPOFBMTPBMMPXTZPVUPMFBSOUP speak and understand spoken Chinese Language Tips without learning Chinese characters. t$IJOFTFJTXSJUUFOXJUIOPTQBDFTCFUXFFOXPSET If this is your objective, you can study your course in the pinyin script. t&BDIDIBSBDUFSJO$IJOFTFDPSSFTQPOETUPBTJOHMFTZMMBCMF tThe meaning of a Chinese syllable depends on the tone with which it is spoken. Chinese has four tones: t3PTFUUB4UPOFHJWFTZPVUIFBCJMJUZUP mā má mǎ mà view pinyin along with the characters. steady high 2 high rising 3 low falling-rising 4 falling You can use this feature as a t"UPOFNBZDIBOHFTMJHIUMZEFQFOEJOHPOUIFUPOFTPGJUTOFJHICPSJOH pronunciation guide for the characters you encounter in the course. -
The Rise of Agricultural Civilization in China: the Disparity Between Archeological Discovery and the Documentary Record and Its Explanation
SINO-PLATONIC PAPERS Number 175 December, 2006 The Rise of Agricultural Civilization in China: The Disparity between Archeological Discovery and the Documentary Record and Its Explanation by Zhou Jixu Center for East Asian Studies, University of Pennsylvania, Philadelphia, Pennsylvania Chinese Department, Sichuan Normal University, Chengdu, Sichuan Victor H. Mair, Editor Sino-Platonic Papers Department of East Asian Languages and Civilizations University of Pennsylvania Philadelphia, PA 19104-6305 USA [email protected] www.sino-platonic.org SINO-PLATONIC PAPERS is an occasional series edited by Victor H. Mair. The purpose of the series is to make available to specialists and the interested public the results of research that, because of its unconventional or controversial nature, might otherwise go unpublished. The editor actively encourages younger, not yet well established, scholars and independent authors to submit manuscripts for consideration. Contributions in any of the major scholarly languages of the world, including Romanized Modern Standard Mandarin (MSM) and Japanese, are acceptable. In special circumstances, papers written in one of the Sinitic topolects (fangyan) may be considered for publication. Although the chief focus of Sino-Platonic Papers is on the intercultural relations of China with other peoples, challenging and creative studies on a wide variety of philological subjects will be entertained. This series is not the place for safe, sober, and stodgy presentations. Sino-Platonic Papers prefers lively work that, while taking reasonable risks to advance the field, capitalizes on brilliant new insights into the development of civilization. The only style-sheet we honor is that of consistency. Where possible, we prefer the usages of the Journal of Asian Studies.