PSI Scientific Report 2010
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Μ → Eγ and Matching at Mw
Eur. Phys. J. C (2016) 76:370 DOI 10.1140/epjc/s10052-016-4207-5 Regular Article - Theoretical Physics μ → eγ and matching at mW Sacha Davidson1,2,3,a 1 IPNL, CNRS/IN2P3, 4 rue E. Fermi, 69622 Villeurbanne Cedex, France 2 Université Lyon 1, Villeurbanne, France 3 Université de Lyon, 69622 Lyon, France Received: 18 March 2016 / Accepted: 14 June 2016 / Published online: 4 July 2016 © The Author(s) 2016. This article is published with open access at Springerlink.com Abstract Several experiments search for μ ↔ e flavour attempt to reconstruct the fundamental Lagrangian of New change, for instance in μ → e conversion, μ → eγ and Physics from the operator coefficients. This is probably not μ → eee¯ . This paper studies how to translate these experi- feasible, but could give interesting perspectives. A first step mental constraints from low energy to a New Physics scale in this “bottom-up” approach, explored in this paper, is to M mW . A basis of QCD × QED-invariant operators (as use Effective Field Theory (EFT) [31] to translate the exper- appropriate below mW ) is reviewed, then run to mW with imental bounds to the coefficients of effective operators at one-loop Renormalisation Group Equations (RGEs) of QCD the New Physics scale M > mW . and QED. At mW , these operators are matched onto SU(2)- The goal would be to start from experimental constraints invariant dimension-six operators, which can continue to run on μ–e flavour change, and obtain at M the best bound up with electroweak RGEs. As an example, the μ → eγ on each coefficient from each observable. -
NATO and Earth Scientists: an Ongoing Collaboration to Assess Geohazards and Contribute to Societal Security in Central Asia and the Caucasus
Article 193 by Alessandro Tibaldi1*, Andrey M. Korzhenkov2, Federico Pasquarè Mariotto3, Derek Rust4, and Nino Tsereteli5 NATO and earth scientists: an ongoing collaboration to assess geohazards and contribute to societal security in Central Asia and the Caucasus 1 Department of Earth and Environmental Sciences, University of Milano-Bicocca, P. della Scienza 4, 20126 Milan, Italy; *Corresponding author, E-mail: [email protected] 2 Laboratory of modelling of seismic processes, Institute of Communication and Information Technologies, Kyrgyz-Russian Slavic University, Kievskaya str. 44, Bishkek 720000, Kyrgyz Republic 3 Department of Theoretical and Applied Sciences, University of Insubria, Via Mazzini 5, 21100 Varese, Italy 4 School of Earth and Environmental Sciences, University of Portsmouth, Barnaby Building, Portsmouth PO1 2UP, UK 5 M. Nodia Institute of Geophysics, M. Javakhishvili Tbilisi State University, 1, Alexidze str. 0171 T, Georgia (Received: July 18, 2017; Revised accepted: February 26, 2018) https://doi.org/10.18814/epiiugs/2018/018011 Geological features and hazards have no geographical and political boundaries. The North Atlantic Treaty Introduction Organization (NATO) has been funding several interna- tional Earth Science research projects in Central Asia Several areas on Earth are subject to natural hazards that threaten and the Caucasus over the last ten years. The projects are human life, settlements and infrastructures. One of the natural haz- ards that may severely affect local areas and communities is an earth- aimed at improving the security of people and the safety quake, as seen, for instance, in the recent sequence of seismic events of infrastructures, and fostering peaceful scientific col- that struck the Caucasus: the 1988 earthquake in Spitak, Armenia laboration between scientists from NATO and non-NATO (Griffin et al., 1991), the 1991 and 2009 Racha (Georgia) earthquakes countries. -
Repositioning of the Global Epicentre of Non-Optimal Cholesterol
Article Repositioning of the global epicentre of non-optimal cholesterol https://doi.org/10.1038/s41586-020-2338-1 NCD Risk Factor Collaboration (NCD-RisC)* Received: 18 October 2019 Accepted: 2 April 2020 High blood cholesterol is typically considered a feature of wealthy western 1,2 Published online: 3 June 2020 countries . However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering Open access medications at varying rates. These changes can have distinct effects on the levels of Check for updates high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiovascular risk— changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. -
Connecting Leading Candidates to the World's Finest Science Jobs, Events
Connecting leading candidates to the world’s finest science jobs, events and other career development resources Click on the to navigate the pages PROMOTE YOUR RECRUITMENT ORGANIZATION EVENTS FILL YOUR VACANCIES BRANDED CONTENT & PROMOTE YOUR EVENTS Our Audience & Reach NATIVE ADVERTISING Multichannel marketing Job listing packages Custom Advertorials Nature Events Guide Employer Profile & Index Profile MULTICHANNEL MARKETING Custom Podcasts & Webcasts EXHIBIT AT CAREER EVENTS Banners *optimized targeting* Case Studies Careers Live Emails London • New York • Singapore Print EDITORIAL FEATURES Spotlights and Career Guides REGIONAL RECRUITMENT Salary Survey, Graduate Survey, Scientist At Work photo competition 2019 OTHER CALENDAR ABOUT US RESOURCES EDITORIAL CALENDAR NATURE CAREERS SPECS Print Specs NATURE RESEARCH Banner Specs Third Party Email Specs Alerts Specs SPRINGER NATURE TERMS & CONDITIONS CONTACT US UK/ROW: +44 (0)20 7843 4961 US: +1 212 726 9270 [email protected] 2 | Nature Careers 2019 Media Options RECRUITMENT PROMOTIONS EVENTS CALENDAR ABOUT US OTHER RESOURCES RECRUITMENT FILL YOUR VACANCIES Our Audience & Reach Job listing packages MULTICHANNEL MARKETING Banners *optimized targeting* Email Print REGIONAL RECRUITMENT 3 | Recruitment | Nature Careers 2019 Media Options RECRUITMENT PROMOTIONS EVENTS CALENDAR ABOUT US OTHER RESOURCES OUR AUDIENCE & REACH Nature Careers Nature Careers is the global career resource, jobs board and events directory for scientists. It is brought to you by Springer Nature, a leading publisher -
Scalable Production of Biliverdin Ixα by Escherichia Coli Dong Chen1, Jason D Brown1, Yukie Kawasaki2, Jerry Bommer3 and Jon Y Takemoto1,2*
Chen et al. BMC Biotechnology 2012, 12:89 http://www.biomedcentral.com/1472-6750/12/89 RESEARCH ARTICLE Open Access Scalable production of biliverdin IXα by Escherichia coli Dong Chen1, Jason D Brown1, Yukie Kawasaki2, Jerry Bommer3 and Jon Y Takemoto1,2* Abstract Background: Biliverdin IXα is produced when heme undergoes reductive ring cleavage at the α-methene bridge catalyzed by heme oxygenase. It is subsequently reduced by biliverdin reductase to bilirubin IXα which is a potent endogenous antioxidant. Biliverdin IXα, through interaction with biliverdin reductase, also initiates signaling pathways leading to anti-inflammatory responses and suppression of cellular pro-inflammatory events. The use of biliverdin IXα as a cytoprotective therapeutic has been suggested, but its clinical development and use is currently limited by insufficient quantity, uncertain purity, and derivation from mammalian materials. To address these limitations, methods to produce, recover and purify biliverdin IXα from bacterial cultures of Escherichia coli were investigated and developed. Results: Recombinant E. coli strains BL21(HO1) and BL21(mHO1) expressing cyanobacterial heme oxygenase gene ho1 and a sequence modified version (mho1) optimized for E. coli expression, respectively, were constructed and shown to produce biliverdin IXα in batch and fed-batch bioreactor cultures. Strain BL21(mHO1) produced roughly twice the amount of biliverdin IXα than did strain BL21(HO1). Lactose either alone or in combination with glycerol supported consistent biliverdin IXα production by strain BL21(mHO1) (up to an average of 23. 5mg L-1 culture) in fed-batch mode and production by strain BL21 (HO1) in batch-mode was scalable to 100L bioreactor culture volumes. -
Personnel Law 2018
2018 BOARD OF THE SWISS FEDERAL INSTITUTES OF TECHNOLOGY ETH BOARD PAUL SCHERRER INSTITUT PERSONNEL LAW BOARD OF THE SWISS FEDERAL INSTITUTES OF TECHNOLOGY ETH BOARD PAUL SCHERRER INSTITUT PERSONNEL LAW Imprint Personnel Law can be obtained at ETH Domain ETH Board Published by Human Resources ETH Board CH-8092 Zurich CH-8092 Zurich www.ethrat.ch Conception / Editor ETH Swiss Federal Institute Martin Sommer / Elisabeth Boettcher of Technology Zurich ETH Board Human Resources CH-8092 Zurich www.ethz.ch Layout and Print Paul Scherrer Institute EPFL Ecublens Human Resources ETH Board, January 2018 CH-1015 Lausanne 16th edition: March 2018 www.epfl.ch Paul Scherrer Institute Human Resources Management CH-5232 Villligen PSI www.psi.ch WSL Swiss Federal Institute for Forest, Snow and Landscape Research Human Resources CH-8903 Birmensdorf www.wsl.ch Empa Swiss Federal Institute of Materials Science & Technology Human Resources CH-8600 Duebendorf www.empa.ch Eawag Swiss Federal Institute of Aquatic Science and Technology Human Resources CH-8600 Duebendorf www.eawag.ch Contents Ordinance of the ETH Board concerning personnel in the Swiss Federal Institutes of Technology Domain (Personnel Ordinance for the ETH Domain, ETH PO) General Provisions 2 Human resources policy 4 Employment relationship 9 Benefits 15 Duties 38 Breach of professional duties 41 Final provisions 43 Appendices 47 Swiss Federal Personnel Law (FPL) General Provisions 54 Commencement and termination of employment 58 Rights and obligations resulting from the employment relationship 60 Data processing 64 Measures of benefit to personnel 70 Occupational Pension Scheme 72 Participation and social partnership 77 Formes of Procedure 78 Implementing Provisions 80 Final Provisions 81 Framework Ordinance for the Swiss Federal Personnel Law (Framework Ordinance FPL) 84 Table of contents Personnel Ordinance for the ETH Domain Chapter 1: General Provisions 2 Art. -
On the Exotic Higgs Decays in Effective Field Theory
Eur. Phys. J. C (2016) 76:514 DOI 10.1140/epjc/s10052-016-4362-8 Regular Article - Theoretical Physics On the exotic Higgs decays in effective field theory Hermès Bélusca-Maïtoa, Adam Falkowskib Laboratoire de Physique Théorique, Université Paris-Sud, Bat. 210, 91405 Orsay, France Received: 22 April 2016 / Accepted: 9 September 2016 / Published online: 22 September 2016 © The Author(s) 2016. This article is published with open access at Springerlink.com Abstract We discuss exotic Higgs decays in an effec- in powers of 1/. The leading effects are expected from tive field theory where the Standard Model is extended by operators of dimension 6, as their coefficients are suppressed dimension-6 operators. We review and update the status of by 1/2. The first classification of dimension-6 operators two-body lepton- and quark-flavor-violating decays involv- was performed in Ref. [1]. For one generation of fermions, ing the Higgs boson. We also comment on the possibility of a complete non-redundant set (henceforth referred to as a observing three-body flavor-violating Higgs decays in this basis) was identified and explicitly written down in Ref. [2]. context. Reference [3] extended this to three generations of fermions, in which case a basis is characterized by 2499 independent parameters. Contents In this paper we are interested in the subset of these operators that lead to exotic decays of the 125 GeV Higgs 1 Introduction ..................... 1 boson. By “exotic” we mean decays that are forbidden in 2 Exotic Higgs couplings from dimension-6 Lagrangian 2 the SM or predicted to occur with an extremely suppressed 3 Two-body Higgs decays .............. -
The Swiss and Dutch Precision Industries
The Swiss and Dutch Precision Industries Opportunities for R&D- cooperation between Switzerland and the Netherlands Innovation Attaché Network The Swiss and Dutch Precision Industries Opportunities for R&D-cooperation between Switzerland and the Netherlands Colofon Ordered by Netherlands Innovation Attaché Network Author Freek Deunk Innovation intern Supervision Erik van den Akker Head Economic Department Eelco van der Eijk Innovation counselor Saskia Harthoorn Senior economic officer Anita van Rozen Senior economic officer Contact [email protected] / [email protected] Date Augustus 2014 Published at: www.innovatie.ch/publicaties Source of the cover picture: http://www.hcatopsectoren.nl/htsm.html -1- Summary Switzerland and the Netherlands are strong and innovative countries with a long history in precision engineering. To increase the cooperation between the countries, this report has reviewed the respective precision engineering industries in both countries. This report could therefore serve as an introduction and reference manual on the relevant R&D-landscape in both countries for those parties who want to cooperate. The report focusses on ‘Mechatronics and Manufacturing’, ‘Components and Circuits’ and ‘Nanotechnology’, and the application-areas ‘Health-tech’, ‘Advanced Instrumentation’ and ‘Semiconductor equipment’. Both countries have top universities and competitive high-tech industries in these fields. The R&D environments in both countries could well work together, as the “precision” of Switzerland may supplement the “creativity” of the Netherlands. Both countries are open and internationally oriented, which is a good start for cooperation, building and extending already existing connections. The role of the governments should be a facilitating one. On both sides research institutes and companies appreciate the network and introductions government bodies can give. -
Downloads Presented on the Abstract Page
bioRxiv preprint doi: https://doi.org/10.1101/2020.04.27.063578; this version posted April 28, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. A systematic examination of preprint platforms for use in the medical and biomedical sciences setting Jamie J Kirkham1*, Naomi Penfold2, Fiona Murphy3, Isabelle Boutron4, John PA Ioannidis5, Jessica K Polka2, David Moher6,7 1Centre for Biostatistics, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom. 2ASAPbio, San Francisco, CA, USA. 3Murphy Mitchell Consulting Ltd. 4Université de Paris, Centre of Research in Epidemiology and Statistics (CRESS), Inserm, Paris, F-75004 France. 5Meta-Research Innovation Center at Stanford (METRICS) and Departments of Medicine, of Epidemiology and Population Health, of Biomedical Data Science, and of Statistics, Stanford University, Stanford, CA, USA. 6Centre for Journalology, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada. 7School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada. *Corresponding Author: Professor Jamie Kirkham Centre for Biostatistics Faculty of Biology, Medicine and Health The University of Manchester Jean McFarlane Building Oxford Road Manchester, M13 9PL, UK Email: [email protected] Tel: +44 (0)161 275 1135 bioRxiv preprint doi: https://doi.org/10.1101/2020.04.27.063578; this version posted April 28, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. -
BSG 50Th Annual Conference, 7
BSG 2021 50th Annual Conference 7 - 9 July 2021 Hosted online by Lancaster University Ageing Past, Present and Future: Innovation and Change Conference Programme Image courtesy of Tom Morbey British50th Annual Society Conference of Gerontology / 7 - 9 July 2021 AnnualHosted online Conference by Lancaster 2017 University SEARCH DOCUMENT To search this document you can click the button above or bring up the Search window by pressing Ctrl-F (Windows) or Command+F (Mac). © Copyright Author 2 2britishgerontology.orgbritishgerontology.org Contents Welcome from the BSG President ........................... 4 Flagship Symposium ................................................. 19 Welcome from the Vice Chancellor, The Averil Osborn Symposium .............................. 20 Lancaster University ..................................................... 5 Sponsors and Exhibitors .......................................... 21 Welcome from the Conference Chair ..................... 5 BSG Emergening Researchers in Ageing ........... 22 Thanks ............................................................................... 7 Conference Ceremonies ........................................... 23 Conference Committee ................................................ 8 Social Events ................................................................ 23 About the Conference ............................................... 10 Join the BSG ................................................................. 27 Timetable at a Glance .............................................. -
Springer Nature’S Hybrid Results of the DEAL- Journals, of Which 9,354 Were of the Research Article Type and 882 of the Non-Research Article Type
Advancing Open Access Publishing in 2020 10,236 publications were published in 2020 through the DEAL agreement in Springer Nature’s hybrid Results of the DEAL- journals, of which 9,354 were of the research article type and 882 of the non-research article type. Another 1,843 articles appeared in Springer Nature’s fully open access journals. Springer Nature Agreement 12079 ARTICLES Authors from 390 different German scientific institutions were involved in these publications. 2020 Authors retaining their rights Open access publishing across disciplines Springer Nature is the second By the end of 2020, 96% of authors According to the disciplines of Scopus, DEAL publications most relevant publisher for chose open access for publishing in in Springer Nature journals were distributed as follows in Elsevier German authors. Springer Nature’s hybrid journals. Their 2020: articles were published under a free Others Health sciences Springer license (CC-BY) without any access Nature In 2020, 18% of all scientific barriers and may thus be disseminated Life sciences articles from Germany were and re-used worldwide. The number Physical sciences Wiley published in Springer Nature of publications for which authors Social sciences + Humanities journals. opted out of open access continues to Other/Multidisciplinary decline. 0 500 1000 1500 2000 2500 3000 3500 4000 Publish and read Open access to key research While authors at over 900 institutions in Springer Nature journals are among the most frequently used publication venues of authors in Germany. Numerous of their Germany are automatically entitled to publish medical and, especially, clinical medicine titles are particularly relevant for German research. -
Coexistence of Phycoerythrin and a Chlorophyll A/B Antenna in a Marine Prokaryote (Prochlorophyta/Cyanobacteria/Phycobilins/Photosynthesis/Endosymbiosis) WOLFGANG R
Proc. Natl. Acad. Sci. USA Vol. 93, pp. 11126-11130, October 1996 Microbiology Coexistence of phycoerythrin and a chlorophyll a/b antenna in a marine prokaryote (Prochlorophyta/cyanobacteria/phycobilins/photosynthesis/endosymbiosis) WOLFGANG R. HESs*t, FREDEIRIC PARTENSKYt, GEORG W. M. VAN DER STAAYI, JOSE' M. GARCIA-FERNANDEZt, THOMAS BORNER*, AND DANIEL VAULOTt *Department of Biology, Humboldt-University, Chausseestrasse 117, D-10115 Berlin, Germany; and tStation Biologique de Roscoff, Centre National de la Recherche Scientifique Unite Propre de Recherche 9042 and Universite Pierre et Marie Curie, BP 74, F-29682 Roscoff Cedex, France Communicated by Hewson Swift, The University of Chicago, Chicago, IL, July 1Z 1996 (received for review June 7, 1996) ABSTRACT Prochlorococcus marinus CCMP 1375, a ubiq- tation maximum of the major chromophore bound by PE-III uitous and ecologically important marine prochlorophyte, corresponds to that of phycourobilin. was found to possess functional genes coding for the a and 1 subunits of a phycobiliprotein. The latter is similar to phy- coerythrins (PE) from marine Synechococcus cyanobacteria MATERIALS AND METHODS and bind a phycourobilin-like pigment as the major chro- Flow Cytometric Measurements. Sea water samples were mophore. However, differences in the sequences of the ca and collected at different depths during the France-Joint Global 13 chains compared with known PE subunits and the presence Ocean Flux Study OLIPAC cruise held in November 1994 of a single bilin attachment site on the a subunit designate it aboard the N.O. l'Atalante. Samples were analyzed immedi- as a novel PE type, which we propose naming PE-III. P. ately using a FACScan (Becton Dickinson) flow cytometer and marinus is the sole prokaryotic organism known so far that cell concentrations of Prochlorococcus and Synechococcus contains chlorophylls a and b as well as phycobilins.