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Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Eli Lilly Canada Not funded by BC Cancer Now marketed. (Verzenio®) Phone: 1-888-545-5972 Contact Patient Support program effective mid-July 2019 Abiraterone Janssen Ortho CAP approval Now marketed tel: 416-382-5078 or 416-805- See Patient Assistance Programs 4648 AGS-16C3F – SAP Astellas Pharma USA CAP approval (no cost) Health Canada Special Access Request Form A Phone 1-224-205-8279 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Genzyme • Contact Clnigen Group to open an account – (MABCAMPATH®) Phone: 905-267-3184 company will send a Cliniport registration form • Complete Cliniport Registration form with an email Distributed through the address for authorizing physician(s) MabCampath Distribution and pharmacist(s) placing the order via Cliniport Program and fax back to +44 1283 494341 which is managed by the • Once registered, company will send guidance on Clinigen Group using the Cliniport portal for ordering, tracking www.clinigengroup.com orders, reassigning vials, and closing out patients records Phone : +44 1283 494340 • Reports detailing all shipments and current status of Fax: +44 1283 494341 Campath can be downloaded through the Cliniport Email: portal customer.services@clinigengr oup.com Alpelisib Novartis Canada Not funded by BC Cancer Now marketed. (Piqray®) Contact Patient Support Program: Piqray PSP 1-877-516-5353 Hoffmann-La Roche Not currently funded by BC Cancer. Now marketed. (TECENTRIQ®) See Patient Assistance Programs

Amivantamab-vmjw Janssen (no cost) Health Canada Special Access Request Form A SAP Tel: 1-800-567-3331 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- [email protected] drogues/index-eng.php

8 Sep 2021 1/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures – SAP EMD Serono CAP approval Now marketed (Bavencio®) A Business of Merck KGaA, Darmstadt, Germany EMD Inc., Canada | 200-2695 North Sheridan Way | Mississauga, Ontario L5K 2N6 | Canada Phone: +1 905 919 0200 ext. 5534 | Mobile: +1 416-729- 3254 | Fax: +1 905 919 0299 www.emdserono.ca - Celgene: CAP approval Now marketed (VIDAZA®) 1-888-712-2353 ext 4807

Aztreonam - SAP Bristol-Myers For inpatients only: (AZACTAM®) 1-514-333-2037 Health Canada Special Access Request Form A http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Bazedoxifene – SAP Martina Vlahakis CAP approval (no cost) Health Canada Special Access Request Form A (CONBRIZA) Pfizer Canada http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Tel: 514-695-0500 or 877- drogues/index-eng.php 633-2001 GSK (no cost) Health Canada Special Access Request Form A – SAP (also known as Tel: +44 20 8047 4856 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- GSK2857916) drogues/index-eng.php – SAP Servier Canada CAP approval (no cost) Health Canada Special Access Request Form A (Beleodaq®) Tel: 450-978-0409 #4381 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php - SAP Valeant Pharmaceuticals CAP approval (cost) Health Canada Special Access Request Form A (TARGRETIN®) Phone: 1-800-361-4261 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Email: drogues/index-eng.php [email protected] m

8 Sep 2021 2/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Takeda Canada Not funded by BC Cancer Now marketed (ALUNBRIG®) 1-844-884-4968 Contact the Patient Assistance Program Tel: 844-884-4968 Buprenorphine – SAP Indivior (no cost) Pre-approval from company required. (Sublocade®) tel: 514-331-1114 Shipped to BC Cancer but transfer to outside pharmacy to dispense Health Canada Special Access Request Form A http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Ipsen Canada Not funded by BC Cancer Now marketed. Contact Ipsen Cares Patient Support (Cobometyx®) tel: 1-855-215-2218 Porgram (1-855-215-2288) for drug access.

Canakinumab Novartis Not funded by BC Cancer Contact the Patient Assistance Program (IDARIA®) EXPOSE – 1-844-279-7673 - SAP Novartis Canada CAP approval (no Cost) Health Canada Special Access Request Form A (Tabrecta®) Fax 1-416-262-4992 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Email drogues/index-eng.php [email protected] Pre-approval from drug company. om Carbidopa – SAP Merke-Frosst N/A Now marketed tel: 1-800-361-7031 x3212

Carfilzomib Not currently funded by BC Cancer Now marketed - (Kyprolis®) Contact the Victory Program (1-888-706-4717) for drug access and private infusion clinic Heritage Pharmaceuticals Inc Now marketed 732-429-1000 local 132

8 Sep 2021 3/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Carmustine Implant Eisai Limited CAP approval (cost) Health Canada Special Access Request Form A (GLIADEL® Wafers) - Company contact http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- SAP Alex Flint Medical Director drogues/index-eng.php Phone: 647-299-2983 or 905-361-7137 Email: [email protected]

Distributor – Idis/Clinigen [email protected] -SAP Astra Zeneca CAP approval (no cost) Pre-approval from company required. Tel: 1-800-565-5877 Email: Health Canada Special Access Request Form A sapcanadaastrazeneca@astr http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- azeneca.com drogues/index-eng.php Sanofi Not funded at BC Cancer Now marketed REACH Patient Support Program (Libtayo®) Tel: 1-855-572-6634 Fax: 1-844-342-4534 Recordarti (cost) Health Canada Special Access Request Form A Hydrochorine – SAP Tel: 647-255-8830 Alternative to mechlorethamine http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- (Legara®) drogues/index-eng.php Chloroprocaine - SAP Fresenius Kabi N/A Health Canada Special Access Request Form A (NESACAINE®) Tel: 905-238-1234 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- email: abascom@fresenius- drogues/index-eng.php kabi.ca , lyophilized Bristol-Myers Squibb Not currently marketed in Canada. powder, – SAP tel: 514-333-2287 Not currently available through SAP. (PLATINOL®) Sanofi Genzyme Canada Health Canada Special Access Request Form A SAP (Evoltra®) Tel: 1-800-265-7927 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- SAP supply from UK drogues/index-eng.php during back order Drug provided free of charge by company. period in Canada

8 Sep 2021 4/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Hospira No longer on back order. tel: 1-866-488-6088

Cytarabine liposome sigma-tau Rare dedication CAP approval (cost) Health Canada Special Access Request Form A injection - SAP Support Centre http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- (DEPOCYT®) US Discontinued by manufacturer (May drogues/index-eng.php tel: 1-888-276-2217 2018) fax: 1-866-489-1898

Daratumumab Janssen Not currently funced by BC Cancer Now Marketed (DARAZALEX®) (cost) See Patient Assistance Programs – liposomal - SAP Please see DaunoXome® - SAP DaunoXome® - SAP GALEN PHARMA (UK) CAP approval Health Canada Special Access Request Form A (liposomal Phone:02838334974 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- daunorubicin) Email: [email protected] drogues/index-eng.php

Decitabine – SAP Eisai CAP approval Health Canada Special Access Request Form A (DACOGEN®) Arlene Nugent http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- phone: 647-302-2947 drogues/index-eng.php email: [email protected]

Denileukin Diftiox - Ligand Pharmaceuticals CAP approval Health Canada Special Access Request Form A SAP 1-508-435-8484 x 353 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- (ONTAK®) drogues/index-eng.php Dexrazoxane Pfizer CAP approval No longer on back order (ZINECARD®) tel: 1-800-387-4974

8 Sep 2021 5/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Diazoxide – SAP Teva Pharmaceuticals CAP approval Health Canada Special Access Request Form A (Proglycem®) Sellerville, PA, USA 18960 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Phone : 305-575-6284 drogues/index-eng.php – SAP GSK (no cost) Health Canada Special Access Request Form A (also known as TSR- tel: +44 20 8047 4856 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- 042) drogues/index-eng.php – non- pegylated liposomal Please see MYOCET® Eltrombopag Glaxo See Patient Assistance Programs Not funded by BC Cancer. – SAP Pfizer Canada CAP approval (no cost) Health Canada Special Access Request Form A Tel: 514-426-7487 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php

Company pre-approval. Canada (no cost) Health Canada Special Access Request Form A SAP Tel: 1-833-944-6546 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Erwinase CGF Pharmatech (cost) Health Canada Special Access Request Form A l- - SAP 1-866-343-0344 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- (ERWINASE®) drogues/index-eng.php Etomidate – SAP Hospira Health Canada Special Access Request Form B (for (AMIDATE®) Tel: 514-905-2619 future use) http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php phosphate - Xedition CAP approval (cost) Health Canada Special Access Request Form A SAP Tel: 905-286-9111 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- (ETOPOPHOS®) drogues/index-eng.php

8 Sep 2021 6/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Foscarnet - SAP Astra Zeneca (cost) For inpatients only: (FOSCAVIR®) 1-800-565-5877 x 6091 Health Canada Special Access Request Form A http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Astra Zeneca See Patient Assistance Programs Now marketed (FASLODEX®) Phone: 1-800-668-6000 GA 101 – SAP see Obintuzumab Glucarpidase - SAP McKesson Canada No CAP required (cost) Health Canada Special Access Request Form A (carboxypeptidase-G2 1-877-384-7425 Eligibility Criteria: http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- [CPDG2] Patients receiving High Dose drogues/index-eng.php VORAXAZE®) (HDMTX) Protocols i.e., This is an urgent Health Canada SAP approval: LYHDMRP; LYHDMTXR; • immediately fax completed form to the SAP and call UMOHDMTX; SAHDMTX, who develop ahead to the SAP call centre, 613-941-2108 MTX toxicity due to delayed elimination. • Confirm with SAP that request is urgent and inform Patients must have both of the them on the status of the patient. SAP can approve following conditions: request within 10 minutes providing all sections on • MTX level does not decrease to the form are complete. expected less than 5 x 10-2 • SAP faxes Letter of Approval (LOA) to McKesson. micromol/L range after 48 h, despite • McKesson delivers the drug within 24 h of receiving leucovorin rescue LOA • Deteriorating renal function If request is after hours: Dose: 50 units/kg IV; for MTX level • Physician calls directly to the SAP call centre, 613- greater than 100 micromol/L may give 941-2108 for authorization. second dose 48 h after first dose. See • SAP calls McKesson, and McKesson ships drug Cancer Drug Manual MTX monograph within 24 h for more dosing information.

NB: drug not on the BC Cancer Benefit Drug List. Hyaluronidase - SAP Amphastar Pharmaceuticals (cost) Health Canada Future Use Request Form B (AMPHADASE®) Inc http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Tel: 1-800-423-4136 drogues/index-eng.php

8 Sep 2021 7/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Ibritumomab - Servier Canada CAP approval (cost) Now marketed. Yttrium90 Tel: 1-800-663-0839 Nuclear Medicine Department to order. (Zevalin®) Iniparib - SAP sanofi-aventis CAP approval (no cost) • Requires pre-approval from company prior to SAP tel: 1-800-363-6364 or request 1-800-265-7927 • SAP form + company approval faxed to SAP email: Health Canada Special Access Request Form A Helene.Grassin@sanofi- http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- aventis.com drogues/index-eng.php Interferon Gamma - Intermune CAP approval Health Canada Special Access Request Form A SAP 1-415-466-2247 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- (ACTIMMUNE®) drogues/index-eng.php Ipatasertib – SAP Roche CAP approval (no cost) Health Canada Special Access Request Form A tel: 905-542-5826 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Itraconazole IV Janssen-Ortho Now marketed 1-800-387-8787 x 5245 – SAP Agios Not funded by BC Cancer (cost) Company’s pre-approval. tel:862-222-5542 Health Canada Special Access Request Form A http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php –SAP R-Pharm US CAP approval Health Canada Special Access Form A (IXEMPRA®) http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- If approved by the company, drogues/index-eng.php ixabepilone is provided at no cost Takeda Canada Not currently funded by BC Cancer. Now marketed. (NINLARO®) See Patient Assistance Programs

8 Sep 2021 8/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures (Lorbrena®) Pfizer Not funded by BC Cancer Now marketed Pfizer Liaison Patient Support Program Tel: 1-844-616-6888 Fax: 1-844-636-6888 Email: [email protected] LOXO 292 – SAP Eli Lilly CAP approval (no cost) Health Canada Special Access Request Form A () LOXO NPP Study team http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Tel: 1-888-406-9574 drogues/index-eng.php

Company pre-approval. Lurbinectedin – SAP Pharma Mar CAP approval (no cost) Health Canada Special Access Request Form A Madrid, Spain http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Tel: +34-91-846-6100 drogues/index-eng.php

Company approval. -L-Lysine Asta Medica Germany Health Canada Special Access Request Form A – SAP 011-4969-40012887 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Mechlorethamine 10 Recordati Rare Disease None (cost) Health Canada Special Access Request Form A mg vial –SAP (USA) http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- (MUSTARGEN®) 847-205-5503 drogues/index-eng.php Discontinued by manufacturer December 31, 2018. See alternative Chlormethine Hydrochloride - SAP Methadone IV For inpatient use only: Methadone IV is no longer available via SAP. Methadone buccal is the replacement. Methoxsalen – SAP Delasco CAP approval Health Canada Special Access Request Form A (8-MOP) 1-800-831-6273 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php * ordered by VGH radio-pharmacy and reimbursed by BC Cancer

8 Sep 2021 9/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Metyrosine Ono Pharmaceuticals Japan Not currently marketed in Canada. Not currently available through SAP. Marketed in Japan and USA. Midazolam – SAP Pfizer N/A Health Canada Special Access Request Form A http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Mifepristone – SAP Association of Reproductive CAP approval Health Canada Special Access Request Form A (MIFEPREX®) Health Professionals http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Or RU-486 tel: 202-466-3825 drogues/index-eng.php fax: 202-466-2826 Miltefostine – SAP Baxter Pharmaceuticals CAP approval Health Canada Special Access Request Form A (MILTEX®) 1-905-281-6691 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Mitomycin-SAP Teva GUBMITO Health Canada Special Access Request Form A -may be accessed via Company contact: http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- SAP during shortage Ky To drogues/index-eng.php of supply in Canada [email protected] Cell 647-680-2527 Mobocertinib – SAP Takeda Canada (no cost) Health Canada Special Access Request Form A (also known as TAK- Tel: 1-844-884-4968 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- 788) drogues/index-eng.php

8 Sep 2021 10/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Kyowa Hakko Kirin: CAP approval (no cost) Health Canada Special Access Request Form A (POTELIGEO®) - SAP http://www.kyowa- http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- kirin.com/index.html drogues/index-eng.php Contact: Doug Grant General Manager, Canada Kyowa Kirin 135 Route 202/206 Suite 6 Bedminster, NJ 07921 USA

Mobile: 908-801-0151 [email protected] m MYOCET® Sopherion Therapeutics, LLC CAP approval Now marketed (non-pegylated PO Box 477 liposomal doxorubicin) East Brunswick, NJ 08816- 0477 Phone: 203-494-8475 Fax: 610-524-8148 Email: [email protected]

In Canada: UPS Supply Chain solutions Phone: 1-800-664-1986 Nab-Sirolimus SAP Bionical-emas (no cost) Health Canada Special Access Request Form A Tel: 1-888-346-8672 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Patient.access@bionical- drogues/index-eng.php emas.com Nanoliposomal Shire Not currently funded by BC Cancer and Patient Assistance Program closed May 2019 Phone: 604-376-2839 new patients currently cannot have (Nal-IRI®) drug administered at BC Cancer (no cost)

8 Sep 2021 11/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Puma Biotech Not funded by BCCA Now marketed (Nerlynx®) tel:1-855-635-2372 Contact Patient Support program effective December 2019. Nimorazole – SAP Azanta CAP approval Health Canada Special Access Request Form A (NIMORAZOLE®) 1-647-968-9887 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Chia Chia Sun: drogues/index-eng.php Email: [email protected] - SAP • YM BIOSCIENCES 905- CAP approval Health Canada Special Access Request Form A 629-9761 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- • Calea (administers drug drogues/index-eng.php distribution) 888-865- 5372 • website www.nimotuzumab- access.com – SAP GSK CAP approval (no cost) Health Canada Special Access Request Form A (ZEJULA®) tel: 1-905-814-2159 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php

Company approval Nirogacestat – SAP SpringWorks therapeutics (no cost) Health Canada Special Access Request Form A [email protected] http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Hoffmann-La Roche CAP approval Now marketed (GAZYVA®) GlaxoSmithKline CAP approval Now marketed (ARZERRA®) Phone: 1-800-387-7374 In Canada, ofatumumab is available via compassionate Fax: 1-800-565-2935 request for patients who meet the approved indication: Email: [email protected] Ofatumumab is indicated for the treatment of patients with chronic lymphocytic (CLL) refractory to and alemtuzumab

8 Sep 2021 12/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Astra Zeneca Not currently funded by BC Cancer Now marketed - (LYNPARZA®) Contact the AstraZeneca Oncology Patient Support Program (1-877-280-6208) for drug access – SAP AstraZeneca Not currently funded by BC Cancer. Now marketed- (TAGRISSO®) Contact the AstraZeneca Oncology Patient Support Program (1-877-280-6208) for drug access Pfizer CAP approval (cost) Now marketed (IBRANCE®) Contact Patient Assistance Program for patients not eligible for BC Cancer funded indication. – SAP Novartis (no cost) Health Canada Special Access Request Form A email: http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- [email protected] drogues/index-eng.php tel: 1-800-363-8883 - Baxalta CAP approval (cost) Now marketed SAP(ONCASPAR®) tel: 905-816-7697 email: [email protected] – SAP Incyte Biosciences Canada (no cost) Health Canada Special Access Request Form A Tel: 1-403-612-7751 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- [email protected] drogues/index-eng.php

Pentamidine Pharmaceutical Partners of (cost) Now marketed Canada tel: 1-877-821-7724

Pentostatin – SAP Pfizer Canada (no cost) Health Canada Special Access Request Form A tel: 514-426-7487 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php

8 Sep 2021 13/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Polatuzumab – SAP Roche Canada CAP approval (no cost) Health Canada Special Access Request Form A tel: 416-457-8701 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php

Company pre-approval. Manufacturer: Aridad CAP approval Now marketed Supplier: Idis House Email: [email protected] - Idispharma CAP approval Now marketed (FOLOTYN®) UK tel: 44 1932 824 031 email: [email protected] – SAP Blue Print Medicines CAP approval (no cost) Health Canada Special Access Request Form A (Gavreto®) Fax 919-800-3983 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Email: drogues/index-eng.php medinfo@blueprintmedicines. com Pre-approval from drug company.

Ramucirumab Eli Lilly Not currently funded by BC Cancer Now marketed - (CYRAMZA®) Contact the ENCIRCLE Patient Support Program (1- 855-545-5922) for drug access and private infusion clinic REOLYSIN® - SAP Oncolytics Biotech CAP approval Health Canada Special Access Request Form A Phone: 403-670-7377 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Fax: 403-283-0858 drogues/index-eng.php RET inhibitor Ignyta CAP and SAP approval if patient will RXDX-105-01 trial – RET altered cancer patients who Contact Rupal Patel: receive treatment at BC Cancer have not received prior RET inhibition [email protected] Company willing to work with HC SAP or alternatively Phone: 853-332-0774 they offer a travel assistance program

8 Sep 2021 14/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Medison Not funded by BCCA Now marketed (Qinlock®) Contact Patient Support program: Tel: 1-647-293-3328 Email: [email protected] Celgene CAP approval Now marketed (ISTODAX®) Sacituzumab Gilead Sciences Canada CAP approval (no cost) Health Canada Special Access Request Form A Govitecan (Trodelvy®) http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- - SAP Company contact: drogues/index-eng.php Wendy Arnott Country Medical Director Gilead Sciences Canada, Inc. 6711 Mississauga Road, suite 600 Mississauga, ON L5N 2W3 O: 905-363-8091 [email protected] /GMCSF SANOFI CAP approval Health Canada Special Access Request Form A (LEUKINE®) - SAP 1-800-265-7927 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Selinexor - SAP Karyopharm Therapeutics CAP approval (no cost) Health Canada Special Access Request Form A tel: 1-917-485-1209 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Selitrectinib Bayer Not currently marketed in Canada. www.bayer.ca Not currently available through SAP. Sepercatinib Eli Lilly Not funded by BCCA Now marketed. (Loxo 292) AstraZeneca The manufacturer will not be providing access to this (AZD6244) product via SAP

8 Sep 2021 15/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Soluvit – SAP Fresenius Canada N/A Health Canada Special Access Request Form A (used with Vitalipid – Benita Schueder http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- SAP) phone: 908-780-3011 drogues/index-eng.php email: bshueder@fresenius- kabi.ca (Odomzo®) SunPharma Canada Inc Not funded by BCCA Now marketed tel: 604 345 2740 Contact Controlled Distribution & Patient Assistance Program: [email protected] 1 844 266 2974 - SAP Amgen Canada CAP approval (no Cost) Health Canada Special Access Request Form A (AMG510) Tel: 604 363 4167 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Email: drogues/index-eng.php [email protected] Pre-approval from drug company. Streptozocin - SAP KEOCYT (cost) Health Canada Special Access Request Form A (ZANOSAR®) France http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- tel: +33 (0)1 42 31 07 10 drogues/index-eng.php email: [email protected] website: www.keocyt.com – SAP Pfizer CAP approval (no cost) Health Canada Special Access Request Form A tel: 1-514-426-7487 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Tazemetostat - SAP Epizyme CAP approval (no Cost) Health Canada Special Access Request Form A (EZH-701) Tel: 1-910-364-7803 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- Email: drogues/index-eng.php [email protected] Pre-approval from drug company. Telotristat Ipsen Not funded by BC Cancer Now marketed. Contact the Patient Assistance Program (Xermelo®) Tel: 1 855 215 2288 Fax: 1 844 686 0661

8 Sep 2021 16/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures – SAP EMD Serono (no cost) Health Canada Special Access Request Form A tel: 1-781-681-2857 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Methapharm Inc (cost) Now marketed (Tepadina®) tel: 1-800-287-7686 – SAP Geigene (no cost) Health Canada Special Access Request Form A (also known as BGB- Tel: 628-239-0631 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- A317) drogues/index-eng.php Pre-approval from company. Hoffmann La-Roche Limited CAP approval Now marketed (ACTEMRA®) tel: 905-542-5859 Toremifene – SAP Orion Pharma CAP approval (cost) Orion Pharma has closed SAP access to new patients (FARESTON®) Phone: +358-10-426-4416 Email: [email protected] TRC105 – SAP Tracon Pharmacuticals CAP approval (no cost) Health Canada Special Access Request Form A (known as tel : 858-251-3489 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- ) drogues/index-eng.php – SAP medac Germany CAP approval (cost) Health Canada Special Access Request Form A tel: +49 (0)4103 8006 – 577 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- email: [email protected] drogues/index-eng.php Trifluridine/tipiracil Taiho Pharma Canada Not funded by BC Cancer Now marketed. (LONSURF®) tel: 905-901-0525 Contact the Conexus Patient Support Program (1-833- 266-3987) for drug access. (TUKYSA®) Seattle Genetics Not funded by BC cancer Contact Patient Assistance Program tel 1-833-464-0728 or email [email protected]

8 Sep 2021 17/18 Drugs With Special Ordering Procedures (SAP Chart)

Drug Supplier BC Cancer Requirements Ordering Procedures Uridine Triacetate – Wellstat Therapeutics (no cost for the drug, cost for shipping) Emergency hotline: SAP Phone: 800-914-0071 800-914-0071 (VISTOGARD®) This number is monitored 24 hours a day, 7 days a Michael Bamat, PhD: week. It is critical that the hotline number be called as [email protected] soon as possible after the overdose occurs or after early-onset severe toxicity is recognized in order to expedite treatment.

Health Canada Special Access Request Form A http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php Paladin Labs – Canadian CAP If not available, could try SAP access (VALTAXIN® distributer Sulfate Inex Pharmaceutical CAP approval 1. Health Canada Special Access Request Form A Lipsomes Injection Corporation 604-419-3211 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- (VSLI) - SAP drogues/index-eng.php 2. Inex Pharmaceutical Corporation approval process Vistonuridine: see Uridine Triacetate Vitalipid – SAP Fresenius Canada N/A Health Canada Special Access Request Form A (used with Soluvit – Benita Schueder http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- SAP) phone: 908-780-3011 drogues/index-eng.php email: bshueder@fresenius- kabi.ca 714X – SAP Cerbe Health Canada Special Access Request Form A Tel: 1-819-564-7883 http://www.hc-sc.gc.ca/dhp-mps/acces/drugs- drogues/index-eng.php

CAP = BC Cancer Compassionate Access Program SAP = Health Canada’s Special Access Programme

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