Anti-CPSF6 monoclonal antibody, clone FQS23909 (DCABH-6140) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to CPSF6

Antigen Description Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3- processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.

Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human CPSF6 aa 1-100 (Cysteine residue). The exact sequence is proprietary.Database link: Q16630

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Rat, Human

Clone FQS23909

Purity Tissue culture supernatant

Conjugate Unconjugated

Applications ICC/IF, Flow Cyt, IP, IHC-P, WB

Positive Control HeLa, 293T, Jurkat and K562 cell lysates; Human breast and Human colon carcinoma tissues; HeLa cells; Jurkat cells; K562 cell lysate.

Format Liquid

Size 100 μl

Buffer pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 0.05% BSA, 49% PBS, 50% Glycerol

Preservative 0.01% Sodium Azide

Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved INFORMATION

Gene Name CPSF6 cleavage and polyadenylation specific factor 6, 68kDa [ Homo sapiens ]

Official Symbol CPSF6

Synonyms CPSF6; cleavage and polyadenylation specific factor 6, 68kDa; cleavage and polyadenylation specific factor 6, 68kD subunit; cleavage and polyadenylation specificity factor subunit 6; CFIM; CFIM68; HPBRII 4; HPBRII 7; protein HPBRII-4/7; CPSF 68 kDa subuni

Entrez Gene ID 11052

Protein Refseq NP_008938

UniProt ID Q16630

Chromosome Location 12q15

Pathway mRNA surveillance pathway, organism-specific biosystem; mRNA surveillance pathway, conserved biosystem;

Function contributes_to RNA binding; mRNA binding; nucleotide binding; protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved